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Key Ratios

New Key Statistics Module, Z-Score and F-Score
Market Cap $M3,630Revenue $M147Net Margin (%)-41.2Z-Score3.3
Enterprise Value $M3,232EPS $-0.6Operating Margin %-35.1F-Score4
P/E(ttm))0Cash Flow Per Share $-0.6Pre-tax Margin (%)-45.2Higher ROA y-yN
Price/Book9.510-y EBITDA Growth Rate %0Quick Ratio7.1Cash flow > EarningsY
Price/Sales26.65-y EBITDA Growth Rate %28.7Current Ratio7.2Lower Leverage y-yY
Price/Cash Flow0y-y EBITDA Growth Rate %0ROA % (ttm)-7.2Higher Current Ratio y-yY
Dividend Yield %0Insider Buy (3m)0ROE % (ttm)-16.0Less Shares Outstanding y-yN
Payout Ratio %0Shares Outstanding M118ROI % (ttm)-13.6Gross Margin Increase y-yN

Gurus Latest Trades with ISIS

Number of guru portfolios checked: 56.
TickerGuruDate Action
Impactdown Price Range
(Average)*
Current Price Change from Average Comment Current Shares
ISISRon Baron 2014-03-31 Buy 0.01%$38.56 - $59
($48.28)
$ 31.39-35%New holding, 45251 sh.45,251
ISISGeorge Soros 2014-03-31 Buy $38.56 - $59
($48.28)
$ 31.39-35%New holding, 5539 sh.5,539
ISISGeorge Soros 2011-06-30 Sold Out $8.54 - $9.38
($8.92)
$ 31.39252%Sold Out0
ISISGeorge Soros 2011-03-31 Buy $8.57 - $10.35
($9.21)
$ 31.39241%New holding, 22300 sh.22,300
ISISJean-Marie Eveillard 2010-12-31 Sold Out -0.01%$8.05 - $10.51
($9.48)
$ 31.39231%Sold Out0
ISISJean-Marie Eveillard 2010-09-30 Buy 0.01%$7.775 - $10.07
($8.76)
$ 31.39258%New holding, 100000 sh.100,000
ISISGeorge Soros 2010-09-30 Sold Out $7.775 - $10.07
($8.76)
$ 31.39258%Sold Out0
ISISGeorge Soros 2010-06-30 Buy $8.84 - $11.13
($9.93)
$ 31.39216%New holding, 16100 sh.16,100
ISISJean-Marie Eveillard 2010-03-31 Sold Out -0.01%$8.66 - $11.76
($10.31)
$ 31.39204%Sold Out0
ISISJean-Marie Eveillard 2009-12-31 Buy 0.01%$9.94 - $14.16
($11.94)
$ 31.39163%New holding, 50000 sh.50,000
ISISJean-Marie Eveillard 2007-12-31 Sold Out $15.4 - $17.69
($16.7)
$ 31.3988%Sold Out0
ISISJean-Marie Eveillard 2007-09-30 Buy $9.74 - $14.97
($12.1)
$ 31.39159%New holding, 25000 sh.25,000
Premium Real Time Picks are included for Premium Members only!!
*The price and date might not be the actual time and price at which the transactions were made. In the case of institutional owners, the date is stated as the last day of their fiscal quarter. The prices are estimates if no accurate information available. Foreign holdings may not be included.

ISIS is held by these Gurus:

Ticker Guru Name Portfolio Date* Current Shares % of Shares Outstanding % of Total Assets Managed Change from Last Holdings Holding History
ISIS George Soros 2014-03-315,53900New Buy
ISIS Ron Baron 2014-03-3145,2510.040.01New Buy
Premium Most recent portfolio changes are included for Premium Members only!


ISIS: Insider Buys/Sells

Click Here for All Insider Trades.
InsiderPosition Date Trades Shares Trade Price ($) Change (%) Details
ISIS PHARMACEUTICALS INCDirector, 10% Owner 2014-07-18Sell13,500$6.66363.51view
ISIS PHARMACEUTICALS INCDirector, 10% Owner 2014-07-11Sell8,050$6.73358.69view
ISIS PHARMACEUTICALS INC10% Owner 2014-07-03Sell4,300$8.07282.53view
Geary Richard SSVP, Development 2014-07-02Sell164$35.95-14.13view
CROOKE STANLEY TChairman and CEO 2014-07-01Sell17,500$35.57-13.21view
O'NEIL PATRICK R.SVP, Legal & General Counsel 2014-07-01Sell1,500$35.33-12.62view
ISIS PHARMACEUTICALS INC10% Owner 2014-06-27Sell7,600$7.88291.75view
BENNETT C FRANKSVP, Antisense Research 2014-06-23Sell11,200$36.78-16.07view
O'NEIL PATRICK R.SVP, Legal and General Counsel 2014-06-19Sell700$35.35-12.67view
CROOKE STANLEY TChairman, President and CEO 2014-06-19Sell11,000$35.1-12.05view

Press Releases about ISIS :

    Quarterly/Annual Reports about ISIS:

    News about ISIS:

    Articles On GuruFocus.com
    Weekly CEO Sells Highlight: Keynote Systems Inc., Isis Pharmaceuticals, Coleman Cable Inc. Jul 01 2013 
    Isis Pharmaceuticals Inc. (ISIS) Director, COO B Lynne Parshall sells 17,200 Shares Dec 29 2010 
    Isis Pharmaceuticals Inc. (ISIS) Chairman, President, CEO Stanley T Crooke sells 32,000 Shares Dec 29 2010 
    Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) Nov 05 2010 
    Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) May 07 2010 
    Guru Stocks at 52-Week Low: The Dun & Bradstreet Corp, FTI Consulting Inc, Terra Nitrogen Company L. Mar 07 2010 
    Guru Stocks at 52-Week Low: Dun & Bradstreet Corp, GameStop Corp, Dean Foods Company, SunPower Corp, Feb 21 2010 
    Weekly Guru Bargains Highlights: Weatherford International, MetroPCS Communications, Isis Pharmaceut Feb 13 2010 
    Weekly Guru Bargain Highlights: Sohu.com Inc, Isis Pharmaceuticals Inc, Netease.com Inc, Barclays PL Feb 06 2010 
    Weekly Guru Bargains Highlights: Isis Pharmaceuticals Inc, MetroPCS Communications Inc, American Int Jan 09 2010 

    More From Our Partners
    Isis Pharma Initiates Phase II Study on ISIS-APO(a) - Analyst Blog Jul 21 2014 - ZACKS

    More From Other Websites
    Nasdaq stocks posting largest percentage increases Jul 24 2014
    Isis Pharma Initiates Phase II Study on ISIS-APO(a) Jul 21 2014
    Isis Pharmaceuticals Initiates Phase 2 Study of ISIS-APO(a) Rx in Patients with High Lp(a) Jul 17 2014
    Isis Pharmaceuticals Initiates Phase 2 Study of ISIS-APO(a) Rx in Patients with High Lp(a) Jul 17 2014
    Isis Pharmaceuticals Earns $1 Million from GSK for Advancing ISIS-TTR Rx Jul 16 2014
    Isis Pharmaceuticals Earns $1 Million from GSK for Advancing ISIS-TTR Rx Jul 16 2014
    What happens when free-speech engines like Twitter and Facebook become megaphones for violence? Jul 15 2014
    Cramer's Lightning Round - BioMarin Deserves To Be Higher (7/14/14) Jul 15 2014
    Markets Edge Higher; Alcoa Profit Beats Street View Jul 09 2014
    One sign mobile payments aren’t working? Militant groups have better brand recognition Jul 07 2014
    Isis Pharmaceuticals Earns $1 Million From GSK for Advancing Hepatitis B Virus Program Jul 02 2014
    Isis Pharmaceuticals Earns $1 Million From GSK for Advancing Hepatitis B Virus Program Jul 02 2014
    Isis - Addressing Some Of The Bull Arguments To My Short Thesis Jul 01 2014
    Isis: Long-Term Kynamro Adverse Events May Apply To Entire ISIS 2.0 Pipeline Jun 26 2014
    Isis Pharma Gets $1M Milestone Payment from Glaxo Jun 25 2014

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