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Key Ratios

New Key Statistics Module, Z-Score and F-Score
Market Cap $M3,988Revenue $M147Net Margin (%)-41.2Z-Score4.2
Enterprise Value $M3,414EPS $-0.6Operating Margin %-35.1F-Score6
P/E(ttm))0Cash Flow Per Share $-0.6Pre-tax Margin (%)-45.2Higher ROA y-yY
Price/Book10.410-y EBITDA Growth Rate %0Quick Ratio6.8Cash flow > EarningsY
Price/Sales25.55-y EBITDA Growth Rate %28.7Current Ratio7.7Lower Leverage y-yY
Price/Cash Flow0y-y EBITDA Growth Rate %0ROA % (ttm)-7.2Higher Current Ratio y-yY
Dividend Yield %0Insider Buy (3m)0ROE % (ttm)-16.0Less Shares Outstanding y-yN
Payout Ratio %0Shares Outstanding M115ROI % (ttm)-13.6Gross Margin Increase y-yN

Gurus Latest Trades with ISIS

Number of guru portfolios checked: 54.
TickerGuruDate Action
Impactdown Price Range
Current Price Change from Average Comment Current Shares
ISISGeorge Soros 2011-06-30 Sold Out $8.54 - $9.38
$ 34.01281%Sold Out0
ISISGeorge Soros 2011-03-31 Buy $8.57 - $10.35
$ 34.01269%New holding, 22300 sh.22,300
ISISJean-Marie Eveillard 2010-12-31 Sold Out -0.01%$8.05 - $10.51
$ 34.01259%Sold Out0
ISISJean-Marie Eveillard 2010-09-30 Buy 0.01%$7.775 - $10.07
$ 34.01288%New holding, 100000 sh.100,000
ISISGeorge Soros 2010-09-30 Sold Out $7.775 - $10.07
$ 34.01288%Sold Out0
ISISGeorge Soros 2010-06-30 Buy $8.84 - $11.13
$ 34.01242%New holding, 16100 sh.16,100
ISISJean-Marie Eveillard 2010-03-31 Sold Out -0.01%$8.66 - $11.76
$ 34.01230%Sold Out0
ISISJean-Marie Eveillard 2009-12-31 Buy 0.01%$9.94 - $14.16
$ 34.01185%New holding, 50000 sh.50,000
ISISJean-Marie Eveillard 2007-12-31 Sold Out $15.4 - $17.69
$ 34.01104%Sold Out0
ISISJean-Marie Eveillard 2007-09-30 Buy $9.74 - $14.97
$ 34.01181%New holding, 25000 sh.25,000
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*The price and date might not be the actual time and price at which the transactions were made. In the case of institutional owners, the date is stated as the last day of their fiscal quarter. The prices are estimates if no accurate information available. Foreign holdings may not be included.

ISIS is held by these Gurus:

Premium Most recent portfolio changes are included for Premium Members only!

ISIS: Insider Buys/Sells

Click Here for All Insider Trades.
InsiderPosition Date Trades Shares Trade Price ($) Change (%) Details
CROOKE STANLEY TChairman, President and CEO 2014-04-02Sell8,800$43.65-20.44 view
O'NEIL PATRICK R.SVP, Legal and General Counsel 2014-04-01Sell1,500$44.4-21.78 view
O'NEIL PATRICK R.SVP, Legal & General Counsel 2014-03-03Sell1,500$50-30.54 view
O'NEIL PATRICK R.SVP, Legal & General Counsel 2014-02-03Sell1,500$50.45-31.16 view
WENDER JOSEPH HDirector 2014-02-03Sell4,700$48.78-28.8 view
PARSHALL B LYNNECOO 2014-01-30Sell89,510$49.49-29.82 view
KLEIN JOSEPH IIIDirector 2014-01-24Sell10,313$48.66-28.63 view
WENDER JOSEPH HDirector 2014-01-22Sell10,000$50.98-31.88 view
Geary Richard SSVP, Development 2014-01-22Sell22,200$50.05-30.61 view
Monia Brett PSVP, Antisense Drug Discovery 2014-01-16Sell821$47.08-26.23 view

Press Releases about ISIS :

    Quarterly/Annual Reports about ISIS:

    News about ISIS:

    Articles On GuruFocus.com
    Weekly CEO Sells Highlight: Keynote Systems Inc., Isis Pharmaceuticals, Coleman Cable Inc. Jul 01 2013 
    Isis Pharmaceuticals Inc. (ISIS) Director, COO B Lynne Parshall sells 17,200 Shares Dec 29 2010 
    Isis Pharmaceuticals Inc. (ISIS) Chairman, President, CEO Stanley T Crooke sells 32,000 Shares Dec 29 2010 
    Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) Nov 05 2010 
    Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) May 07 2010 
    Guru Stocks at 52-Week Low: The Dun & Bradstreet Corp, FTI Consulting Inc, Terra Nitrogen Company L. Mar 07 2010 
    Guru Stocks at 52-Week Low: Dun & Bradstreet Corp, GameStop Corp, Dean Foods Company, SunPower Corp, Feb 21 2010 
    Weekly Guru Bargains Highlights: Weatherford International, MetroPCS Communications, Isis Pharmaceut Feb 13 2010 
    Weekly Guru Bargain Highlights: Sohu.com Inc, Isis Pharmaceuticals Inc, Netease.com Inc, Barclays PL Feb 06 2010 
    Weekly Guru Bargains Highlights: Isis Pharmaceuticals Inc, MetroPCS Communications Inc, American Int Jan 09 2010 

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