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Key Ratios

New Key Statistics Module, Z-Score and F-Score
Market Cap $M7,542Revenue $M214Net Margin (%)-18.2Z-Score7.1
Enterprise Value $M7,271EPS $-0.3Operating Margin %-22.3F-Score3
P/E(ttm))0Cash Flow Per Share $-0.6Pre-tax Margin (%)-25.4Higher ROA y-yY
Price/Book28.810-y EBITDA Growth Rate %0Quick Ratio7.2Cash flow > EarningsY
Price/Sales34.85-y EBITDA Growth Rate %7.4Current Ratio7.3Lower Leverage y-yN
Price/Cash Flow0y-y EBITDA Growth Rate %0ROA % (ttm)-4.6Higher Current Ratio y-yN
Dividend Yield %0Insider Buy (3m)0ROE % (ttm)-11.3Less Shares Outstanding y-yN
Payout Ratio %0Shares Outstanding M118ROI % (ttm)-13.6Gross Margin Increase y-yN

Gurus Latest Trades with ISIS

Number of guru portfolios checked: 84. (List those with share number changes of more than 20%, or impact to portfolio more than 0.1%)
TickerGuruDate Action
Impactdown Price Range
(Average)*
Current Price Change from Average Comment Current Shares
ISISRon Baron 2014-06-30 Sold Out -0.01%$22.98 - $43.33
($31.44)
$ 63.3750%Sold Out0
ISISRon Baron 2014-03-31 Buy 0.01%$38.56 - $59
($48.28)
$ 63.3724%New holding45,251
ISISJean-Marie Eveillard 2010-12-31 Sold Out -0.01%$8.05 - $10.51
($9.48)
$ 63.3785%Sold Out0
ISISJean-Marie Eveillard 2010-09-30 Buy 0.01%$7.775 - $10.07
($8.76)
$ 63.3786%New holding100,000
ISISJean-Marie Eveillard 2010-03-31 Sold Out -0.01%$8.66 - $11.76
($10.31)
$ 63.3784%Sold Out0
ISISJean-Marie Eveillard 2009-12-31 Buy 0.01%$9.94 - $14.16
($11.94)
$ 63.3781%New holding50,000
Premium Real Time Picks are included for Premium Members only!!
*The price and date might not be the actual time and price at which the transactions were made. In the case of institutional owners, the date is stated as the last day of their fiscal quarter. The prices are estimates if no accurate information available. Foreign holdings may not be included.

ISIS is held by these Gurus:

Premium Most recent portfolio changes are included for Premium Members only!


ISIS: Insider Buys/Sells

Click Here for All Insider Trades.
InsiderPosition Date Trades Shares Trade Price ($) Change (%) Details
BENNETT C FRANKSVP, Antisense Research 2015-03-24Sell15,000$70.61-10.25view
O'NEIL PATRICK R.SVP, Legal & General Counsel 2015-03-19Sell30,525$74.85-15.34view
Geary Richard SSVP, Development 2015-03-19Sell8,000$75-15.51view
HOUGEN ELIZABETH LSVP, Finance & CFO 2015-03-19Sell10,000$73.33-13.58view
WENDER JOSEPH HDirector 2015-03-18Sell12,500$71.41-11.26view
O'NEIL PATRICK R.SVP, Legal & General Counsel 2015-03-05Sell5,800$71.67-11.58view
WENDER JOSEPH HDirector 2015-03-05Sell12,500$71.61-11.51view
KLEIN JOSEPH IIIDirector 2015-03-05Sell7,000$70.95-10.68view
Geary Richard SSVP, Development 2015-03-05Sell18,095$71.15-10.93view
HOUGEN ELIZABETH LSVP, Finance & CFO 2015-03-05Sell28,094$71.57-11.46view

Press Releases about ISIS :

    Quarterly/Annual Reports about ISIS:

    News about ISIS:

    Articles On GuruFocus.com
    Value vs. Growth: Is Jim Cramer Right about ISIS Pharmaceuticals? Dec 14 2014 
    Weekly CEO Sells Highlight: Keynote Systems Inc., Isis Pharmaceuticals, Coleman Cable Inc. Jul 01 2013 
    Isis Pharmaceuticals Inc. (ISIS) Director, COO B Lynne Parshall sells 17,200 Shares Dec 30 2010 
    Isis Pharmaceuticals Inc. (ISIS) Chairman, President, CEO Stanley T Crooke sells 32,000 Shares Dec 30 2010 
    Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) Nov 05 2010 
    Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) May 07 2010 
    Guru Stocks at 52-Week Low: The Dun & Bradstreet Corp, FTI Consulting Inc, Terra Nitrogen Company L. Mar 08 2010 
    Guru Stocks at 52-Week Low: Dun & Bradstreet Corp, GameStop Corp, Dean Foods Company, SunPower Corp, Feb 21 2010 
    Weekly Guru Bargains Highlights: Weatherford International, MetroPCS Communications, Isis Pharmaceut Feb 14 2010 
    Weekly Guru Bargain Highlights: Sohu.com Inc, Isis Pharmaceuticals Inc, Netease.com Inc, Barclays PL Feb 06 2010 

    More From Other Websites
    'Mad Money' Lightning Round: Buy, Buy, Buy ConocoPhillips Mar 26 2015
    Lightning Round: It's the center of a blast zone Mar 25 2015
    Cramer Remix: The selloff was made for this stock Mar 25 2015
    Isis Pharmaceuticals Reports Phase I Data on Lipid Candidate - Analyst Blog Mar 24 2015
    Isis Pharmaceuticals (ISIS) Stock Falls Today After Antisense Drug Trial Data Mar 23 2015
    Isis Pharmaceuticals Reports Positive Phase 1 Data on Isis-ANGPTL3Rx Mar 23 2015
    Isis Pharmaceuticals Earns $9M for Advancing ISIS-SMN Rx in Infants With Spinal Muscular Atrophy Mar 23 2015
    Isis Pharmaceuticals Reports Positive Phase 1 Data on Isis-ANGPTL3Rx Mar 23 2015
    3 Reasons Isis Is Worth Every Penny Mar 20 2015
    Small-Cap Growth ETFs Restore Leadership Role Mar 19 2015
    Remarkable Biotech Runs Continue Mar 18 2015
    Lightning Round: The downgrade was wrong on this Mar 16 2015
    Could This Drug Make Isis Pharmaceuticals Soar? Mar 11 2015
    Can Isis Pharmaceuticals (ISIS) Run Higher on Strong Earnings Estimate Revisions? - Tale of the Tape Mar 10 2015
    Isis Pharmaceuticals Earns Milestone Payment from Biogen - Analyst Blog Mar 09 2015
    Isis Pharmaceuticals Earns $15 Million From GSK for Advancing ISIS-TTR Rx Mar 06 2015
    Can The Uptrend Continue for ISIS Pharmaceuticals (ISIS)? - Tale of the Tape Mar 06 2015
    Isis Pharmaceuticals Earns $9M for Advancing ISIS-SMN Rx in Infants With Spinal Muscular Atrophy Mar 06 2015
    10-K for Isis Pharmaceuticals, Inc. Mar 05 2015
    Expect More M&A Activity In Red-Hot Biotech Group Mar 05 2015

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