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Key Ratios

New Key Statistics Module, Z-Score and F-Score
Market Cap $M6,890Revenue $M214Net Margin (%)-9.8Altman Z-Score5.7
Enterprise Value $M6,657EPS $-0.3Operating Margin %-11.0Piotroski F-Score4
P/E(ttm)--Beneish M-Score-1.5Pre-tax Margin (%)-15.4Higher ROA y-yY
Price/Book24.310-y EBITDA Growth Rate %--Quick Ratio8.3Cash flow > EarningsY
Price/Sales26.65-y EBITDA Growth Rate %7.4Current Ratio8.3Lower Leverage y-yN
Price/Free Cash Flow--y-y EBITDA Growth Rate %--ROA % (ttm)-2.8Higher Current Ratio y-yY
Dividend Yield %--PEG--ROE % (ttm)-7.5Less Shares Outstanding y-yN
Payout Ratio %--Shares Outstanding M120ROIC % (ttm)-2,818.4Gross Margin Increase y-yN

Gurus Latest Trades with ISIS

Number of guru portfolios checked: 68.
TickerGuruDate Action
Impactdown Price Range
(Average)*
Current Price Change from Average Comment Current Shares
ISISJoel Greenblatt 2015-03-31 Reduce$58.83 - $77.08
($67.85)
$ 56.13-17%Reduce 9.75%7,892
ISISJoel Greenblatt 2014-12-31 Buy $36.46 - $65.09
($49.54)
$ 56.1313%New holding8,745
ISISRon Baron 2014-06-30 Sold Out -0.01%$22.98 - $43.33
($31.44)
$ 56.1379%Sold Out0
ISISGeorge Soros 2014-06-30 Sold Out $22.98 - $43.33
($31.44)
$ 56.1379%Sold Out0
ISISRon Baron 2014-03-31 Buy 0.01%$38.56 - $59
($48.28)
$ 56.1316%New holding45,251
ISISGeorge Soros 2014-03-31 Buy $38.56 - $59
($48.28)
$ 56.1316%New holding5,539
ISISGeorge Soros 2011-06-30 Sold Out $8.54 - $9.38
($8.92)
$ 56.13529%Sold Out0
ISISGeorge Soros 2011-03-31 Buy $8.57 - $10.35
($9.21)
$ 56.13509%New holding22,300
ISISFirst Eagle Investment 2010-12-31 Sold Out -0.01%$8.05 - $10.51
($9.48)
$ 56.13492%Sold Out0
ISISFirst Eagle Investment 2010-09-30 Buy 0.01%$7.775 - $10.07
($8.76)
$ 56.13541%New holding100,000
ISISGeorge Soros 2010-09-30 Sold Out $7.775 - $10.07
($8.76)
$ 56.13541%Sold Out0
ISISGeorge Soros 2010-06-30 Buy $8.84 - $11.13
($9.93)
$ 56.13465%New holding16,100
ISISFirst Eagle Investment 2010-03-31 Sold Out -0.01%$8.66 - $11.76
($10.31)
$ 56.13444%Sold Out0
ISISFirst Eagle Investment 2009-12-31 Buy 0.01%$9.94 - $14.16
($11.94)
$ 56.13370%New holding50,000
Premium Real Time Picks are included for Premium Members only!!
*The price and date might not be the actual time and price at which the transactions were made. In the case of institutional owners, the date is stated as the last day of their fiscal quarter. The prices are estimates if no accurate information available. Foreign holdings may not be included.

ISIS is held by these investors:

Premium Most recent portfolio changes are included for Premium Members only!


ISIS: Insider Buys/Sells

Click Here for All Insider Trades.
InsiderPosition Date Trades Shares Trade Price ($) Change (%) Details
Monia Brett PSVP, Antisense Drug Discovery 2015-07-02Sell198$56.3-0.3view
PARSHALL B LYNNECOO & Secretary 2015-07-01Sell6,218$57.56-2.48view
CROOKE STANLEY TChairman and CEO 2015-07-01Sell6,175$57.56-2.48view
Monia Brett PSVP, Antisense Drug Discovery 2015-06-08Sell7,600$66.22-15.24view
MUTO FREDERICK TDirector 2015-06-01Sell10,000$66.91-16.11view
PARSHALL B LYNNECOO & Secretary 2015-04-07Sell5,565$63.07-11view
CROOKE STANLEY TChairman and CEO 2015-04-07Sell22,377$63.07-11view
PARSHALL B LYNNECOO & Secretary 2015-04-01Sell5,377$61.93-9.37view
CROOKE STANLEY TChairman and CEO 2015-04-01Sell21,623$61.93-9.37view
BENNETT C FRANKSVP, Antisense Research 2015-03-24Sell15,000$70.61-20.51view

Quarterly/Annual Reports about ISIS:

News about ISIS:

Articles On GuruFocus.com
buffet May 31 2015 
buffet May 31 2015 
Bayer Enters Into Collaboration With Isis For Enhancing Its Drug Portfolio May 07 2015 
Analysts Provide Update for Biogen, PTC Therapeutics, GW Pharma, and Isis Pharma Apr 22 2015 
Value vs. Growth: Is Jim Cramer Right about ISIS Pharmaceuticals? Dec 13 2014 
Weekly CEO Sells Highlight: Keynote Systems Inc., Isis Pharmaceuticals, Coleman Cable Inc. Jul 01 2013 
Isis Pharmaceuticals Inc. (ISIS) Director, COO B Lynne Parshall sells 17,200 Shares Dec 29 2010 
Isis Pharmaceuticals Inc. (ISIS) Chairman, President, CEO Stanley T Crooke sells 32,000 Shares Dec 29 2010 
Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) Nov 05 2010 
Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) May 07 2010 

More From Other Websites
ISIS PHARMACEUTICALS INC Files SEC form 8-K, Amendments to Articles of Inc. or Bylaws; Change in... Jul 02 2015
Webcast Alert: Corporate Presentation at the 2015 Isis Pharmaceuticals Annual Stockholder Meeting Jun 30 2015
Webcast Alert: Corporate Presentation at the 2015 Isis Pharmaceuticals Annual Stockholder Meeting Jun 30 2015
ISIS Pharmaceuticals Promoted to the Large-Cap Russell 1000 Index Jun 29 2015
ISIS Pharmaceuticals Promoted to the Large-Cap Russell 1000 Index Jun 29 2015
Even More Data From Isis Pharmaceuticals Jun 25 2015
Isis Pharmaceuticals Up on Spinal Muscular Atrophy Data - Analyst Blog Jun 23 2015
ISIS Pharma Still Undervalued, Needham Says Jun 23 2015
Isis Pharmaceuticals Reports Data from ISIS-SMN Rx in Children with Spinal Muscular Atrophy Jun 22 2015
Isis Pharmaceuticals Reports Data from ISIS-SMN Rx in Children with Spinal Muscular Atrophy Jun 22 2015
ISIS PHARMACEUTICALS INC Files SEC form 8-K, Entry into a Material Definitive Agreement, Creation of... Jun 19 2015
Isis Pharmaceuticals' 3 Most Important Numbers Jun 16 2015
Isis Pharmaceuticals to Present a General Corporate Update at its 2015 Annual Meeting of... Jun 16 2015
Isis Pharmaceuticals to Present a General Corporate Update at its 2015 Annual Meeting of... Jun 16 2015
Isis Pharmaceuticals Up on Positive Data on ISIS-SMNRx - Analyst Blog Jun 12 2015
Edited Transcript of ISIS conference call or presentation 11-Jun-15 12:30pm GMT Jun 12 2015
Jim Cramer's Top Takeaways: Axovant Sciences, AmerisourceBergen, Isis Pharmaceuticals Jun 12 2015
Isis Reports Solid Phase 2 SMA Data Jun 11 2015
Edited Transcript of ISIS presentation 10-Jun-15 9:40pm GMT Jun 11 2015
Jim Cramer's 'Mad Money' Recap: The Beginning of the Bottom? Jun 11 2015

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