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Key Ratios

New Key Statistics Module, Z-Score and F-Score
Market Cap $M4,573Revenue $M147Net Margin (%)-61.0Z-Score4.8
Enterprise Value $M4,216EPS $-0.6Operating Margin %-54.1F-Score2
P/E(ttm))0Cash Flow Per Share $-0.6Pre-tax Margin (%)-65.1Higher ROA y-yN
Price/Book12.210-y EBITDA Growth Rate %0Quick Ratio6.9Cash flow > EarningsY
Price/Sales29.55-y EBITDA Growth Rate %28.7Current Ratio7.0Lower Leverage y-yY
Price/Cash Flow0y-y EBITDA Growth Rate %0ROA % (ttm)-11.3Higher Current Ratio y-yN
Dividend Yield %0Insider Buy (3m)0ROE % (ttm)-25.1Less Shares Outstanding y-yN
Payout Ratio %0Shares Outstanding M118ROI % (ttm)-13.6Gross Margin Increase y-yN

Gurus Latest Trades with ISIS

Number of guru portfolios checked: 56. (List those with share number changes of more than 20%, or impact to portfolio more than 0.1%)
TickerGuruDate Action
Impactdown Price Range
Current Price Change from Average Comment Current Shares
ISISGeorge Soros 2014-06-30 Sold Out $22.98 - $43.33
$ 38.0621%Sold Out0
ISISRon Baron 2014-06-30 Sold Out -0.01%$22.98 - $43.33
$ 38.0621%Sold Out0
ISISRon Baron 2014-03-31 Buy 0.01%$38.56 - $59
$ 38.06-21%New holding, 45251 sh.45,251
ISISGeorge Soros 2014-03-31 Buy $38.56 - $59
$ 38.06-21%New holding, 5539 sh.5,539
ISISGeorge Soros 2011-06-30 Sold Out $8.54 - $9.38
$ 38.06327%Sold Out0
ISISGeorge Soros 2011-03-31 Buy $8.57 - $10.35
$ 38.06313%New holding, 22300 sh.22,300
ISISJean-Marie Eveillard 2010-12-31 Sold Out -0.01%$8.05 - $10.51
$ 38.06302%Sold Out0
ISISJean-Marie Eveillard 2010-09-30 Buy 0.01%$7.775 - $10.07
$ 38.06334%New holding, 100000 sh.100,000
ISISGeorge Soros 2010-09-30 Sold Out $7.775 - $10.07
$ 38.06334%Sold Out0
ISISGeorge Soros 2010-06-30 Buy $8.84 - $11.13
$ 38.06283%New holding, 16100 sh.16,100
ISISJean-Marie Eveillard 2010-03-31 Sold Out -0.01%$8.66 - $11.76
$ 38.06269%Sold Out0
ISISJean-Marie Eveillard 2009-12-31 Buy 0.01%$9.94 - $14.16
$ 38.06219%New holding, 50000 sh.50,000
ISISJean-Marie Eveillard 2007-12-31 Sold Out $15.4 - $17.69
$ 38.06128%Sold Out0
ISISJean-Marie Eveillard 2007-09-30 Buy $9.74 - $14.97
$ 38.06214%New holding, 25000 sh.25,000
Premium Real Time Picks are included for Premium Members only!!
*The price and date might not be the actual time and price at which the transactions were made. In the case of institutional owners, the date is stated as the last day of their fiscal quarter. The prices are estimates if no accurate information available. Foreign holdings may not be included.

ISIS is held by these Gurus:

Ticker Guru Name Portfolio Date* Current Shares % of Shares Outstanding % of Total Assets Managed Change from Last Holdings Holding History
ISIS Ron Baron 2014-06-30000Sold Out
ISIS George Soros 2014-06-30000Sold Out
Premium Most recent portfolio changes are included for Premium Members only!

ISIS: Insider Buys/Sells

Click Here for All Insider Trades.
InsiderPosition Date Trades Shares Trade Price ($) Change (%) Details
ISIS PHARMACEUTICALS INCDirector, 10% Owner 2014-09-12Sell8,900$7.85438.98view
ISIS PHARMACEUTICALS INCDirector, 10% Owner 2014-09-05Sell10,050$7.07498.44view
O'NEIL PATRICK R.SVP, Legal and General Counsel 2014-09-02Sell1,500$40.444.62view
PARSHALL B LYNNECOO 2014-09-02Sell11,071$40.245.14view
ISIS PHARMACEUTICALS INCDirector, 10% Owner 2014-08-29Sell5,000$7504.43view
BENNETT C FRANKSVP, Antisense Research 2014-08-27Sell5,000$40.534.39view
Monia Brett PSVP, Antisense Drug Discovery 2014-08-26Sell27,344$38.1410.93view
ISIS PHARMACEUTICALS INCDirector, 10% Owner 2014-08-22Sell10,750$6.89514.08view
ISIS PHARMACEUTICALS INCDirector, 10% Owner 2014-08-15Sell5,450$7.01503.57view
CROOKE STANLEY TChairman, President and CEO 2014-08-13Sell17,100$35.4519.35view

Press Releases about ISIS :

    Quarterly/Annual Reports about ISIS:

    News about ISIS:

    Articles On GuruFocus.com
    Weekly CEO Sells Highlight: Keynote Systems Inc., Isis Pharmaceuticals, Coleman Cable Inc. Jul 01 2013 
    Isis Pharmaceuticals Inc. (ISIS) Director, COO B Lynne Parshall sells 17,200 Shares Dec 29 2010 
    Isis Pharmaceuticals Inc. (ISIS) Chairman, President, CEO Stanley T Crooke sells 32,000 Shares Dec 29 2010 
    Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) Nov 05 2010 
    Isis Pharmaceuticals Inc. Reports Operating Results (10-Q) May 07 2010 
    Guru Stocks at 52-Week Low: The Dun & Bradstreet Corp, FTI Consulting Inc, Terra Nitrogen Company L. Mar 07 2010 
    Guru Stocks at 52-Week Low: Dun & Bradstreet Corp, GameStop Corp, Dean Foods Company, SunPower Corp, Feb 21 2010 
    Weekly Guru Bargains Highlights: Weatherford International, MetroPCS Communications, Isis Pharmaceut Feb 13 2010 
    Weekly Guru Bargain Highlights: Sohu.com Inc, Isis Pharmaceuticals Inc, Netease.com Inc, Barclays PL Feb 06 2010 
    Weekly Guru Bargains Highlights: Isis Pharmaceuticals Inc, MetroPCS Communications Inc, American Int Jan 09 2010 

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    Isis Pharmaceuticals Starts Phase III Study on ISIS-APOCIIIRx Aug 29 2014
    3 Health Care Stocks Pushing The Sector Higher Aug 28 2014
    Isis Pharmaceuticals Initiates Phase 3 Study of ISIS-APOCIII Rx in Patients with FCS Aug 28 2014
    Companies With ?ISIS? Name Get Unwanted Attention Aug 27 2014
    Isis Pharmaceuticals Finally Breaks Out Aug 27 2014
    Should you buy ISIS? No, not that one Aug 27 2014
    Isis Pharmaceuticals, Inc. (ISIS) Surges: Stock Moves 10.8% Higher Aug 27 2014
    [video] Stock Pops & Drops: ISIS, DSW, TSL, SAFM Aug 26 2014
    Winners & Losers From Tuesday, August 26 Aug 26 2014

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