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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Jack KhattarPresident, CEO438,5730.92%2015-03-19
Padmanabh P. BhattSr. VP of IP; CSO107,3060.22%2015-03-03
Jones W. BryanVP of Business Development67,9800.14%2015-03-30
Tami Tillotson MartinVP of Regulatory Affairs50,6250.11%2012-12-12
William NuergeDirector23,750less than 0.1%2015-03-03
Dr. John M. Siebert,PhDDirector19,563less than 0.1%2015-03-03
Gregory S. PatrickVP, CFO12,434less than 0.1%2015-03-03
Dr. Stefan K.F. Schwabe, M.D., Ph.D.N/A8,476less than 0.1%2015-03-03
Mr. Victor VaughnN/A6,287less than 0.1%2015-03-03
Frederick M. HudsonDirector5,000less than 0.1%2015-03-03

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Bryan Jones W.VP of Business Development2015-03-30Sell6,71267,980$12.0280.712.1567,980 (Direct)
Bryan Jones W.VP of Business Development2015-03-24Sell1,90067,980$1222.812.3367,980 (Direct)
Bhatt Padmanabh P.Sr. VP of IP; CSO2013-08-19Sell2,28551,806$8.2118.864.1951,806 (Direct)
BIGHAM MICHAELDirector2013-03-22Buy35,00035,000$5.41189.4149.17
5,000 (By Beatrice Emerson Bigham Trust U/A DTD 2/28/2001)
5,000 (By Cabot Forbes Bigham Trust U/A DTD 10/11/1996)
25,000 (By Michael F Bigham CRUT U/A DTD 11/23/1994)
SIEBERT JOHN MDirector2013-03-21Buy3,00015,188$5.516.5145.0915,188 (Direct)
Khattar Jack A.President, CEO
(Click for the stocks that their CEOs have bought)
2013-03-15Buy10,0001,537,058$6.1561.5119.19412,058 (Direct)
1,125,000 (By the KBT Trust)
PATRICK GREGORY SVP, CFO2013-03-14Buy5,0008,903$6.9534.893.968,903 (Direct)
ORBIMED ADVISORS LLC10% Owner2013-02-13Sell302,1833,000,000$7.552281.578.54
2,183,000 (See Footnotes(F3,F4,F6))
817,000 (See Footnotes(F3,F5,F6))
ORBIMED ADVISORS LLC10% Owner2012-12-18Sell297,8153,302,183$6.922060.994.8
0 (See Footnotes(F3,F6))
2,402,600 (See Footnotes(F4,F6))
899,583 (See Footnotes(F5,F6))
SIEBERT JOHN MDirector2012-12-04Buy7,00010,000$8.145765.610,000 (Direct)
PATRICK GREGORY SVP, CFO2012-05-04Buy3,0003,000$515169.63,000 (Direct)
SIEBERT JOHN MDirector2012-05-04Buy3,0003,000$515169.63,000 (Direct)
Hudson Frederick M.Director2012-05-04Buy5,0005,000$525169.65,000 (Direct)
Khattar Jack A.President, CEO2012-05-04Buy5,0001,527,058$525169.6402,058 (Direct)
1,125,000 (By the KBT Trust)
Nuerge William A.Director2012-05-04Buy15,00023,750$575169.623,750 (Direct)
SHEFFERY MICHAEL BDirector2012-05-04Buy1,100,0005,475,286$55500169.6
1,668,472 (By OrbiMed Private Investments II, LP)
899,583 (By OrbiMed Private Investments II (QP), LP)
206,816 (By UBS Juniper Crossover Fund, L.L.C.)
2,402,600 (by OrbiMed Private Investments II LP)
297,815 (By UBS Juniper Crossover Fund, L.L.C)
Martin Tami TillotsonVP of Regulatory Affairs2012-05-04Buy2,5002,500$512.5169.62,500 (Direct)
NEWHALL CHARLES W IIIDirector, 10% Owner2012-05-04Buy4,400,00010,641,250$522000169.6
10,641,250 (See Note 2)
BARRETT M JAMESDirector, 10% Owner2012-05-04Buy4,400,00010,641,250$522000169.6
10,641,250 (See Note 2)
NEW ENTERPRISE ASSOCIATES 11 L10% Owner2012-05-04Buy4,400,00010,641,250$522000169.610,641,250 (Direct)
ORBIMED ADVISORS LLCDirector, 10% Owner2012-05-04Buy1,100,0003,599,998$55500169.6
2,402,600 (See Footnotes(F2,F3,F6))
899,583 (See Footnotes(F2,F4,F6))
297,815 (See Footnotes(F2,F5,F6))
Abingworth Management LTD10% Owner2012-05-04Buy1,100,0003,600,000$55500169.6
3,600,000 (See Notes)

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

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