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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Jack KhattarN/A444,1240.9%2016-03-29
Dr. M. James Barrett,PhDDirector97,3550.2%2016-03-16
Charles W. Newhall,IIIN/A92,2980.19%2016-03-01
Jones W. BryanN/A67,9800.14%2015-03-30
Padmanabh P. BhattSr. VP of IP, CSO57,3060.12%2016-04-11
Tami Tillotson MartinN/A50,6250.1%2012-12-12
William NuergeN/A23,750less than 0.1%2016-03-01
Dr. John M. Siebert,PhDN/A19,563less than 0.1%2016-03-01
Gregory S. PatrickVP, CFO8,081less than 0.1%2016-03-01
Mr. Victor VaughnN/A7,024less than 0.1%2016-03-01

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Bhatt Padmanabh P.Sr. VP of IP, CSO2016-04-11Sell30,76257,306$16.49507.3-3.5857,306 (Direct)
Bhatt Padmanabh P.Sr. VP of IP, CSO2015-12-09Sell14,23888,068$14.9212.16.7188,068 (Direct)
BARRETT M JAMESDirector2015-12-08Sell212,970230,710$14.563100.89.2115,355 (Direct)
0 (See Note 5)
57,678 (See Note 1)
33,360 (See Note 2)
24,317 (See Note 3)
BARRETT M JAMESDirector2015-11-25Sell16,1793,968,483$16.35264.5-2.7573,929 (Direct)
3,820,625 (See Note 2)
36,965 (See Note 3)
21,380 (See Note 4)
15,584 (See Note 5)
BARRETT M JAMESDirector2015-11-18Sell93,0003,968,483$16.611544.7-4.2773,929 (Direct)
0 (See Note 6)
3,820,625 (See Note 1)
36,965 (See Note 2)
21,380 (See Note 3)
15,584 (See Note 4)
BARRETT M JAMESDirector2015-11-16Sell119,6504,061,483$16.241943.1-2.0973,929 (Direct)
93,000 (See Note 6)
3,820,625 (See Note 1)
36,965 (See Note 2)
21,380 (See Note 3)
15,584 (See Note 4)
Bhatt Padmanabh P.Sr. VP of IP, CSO2015-11-04Sell5,000102,306$19.999.5-20.1102,306 (Direct)
Schwabe Stefan K.F.Executive Vice President R&D2015-07-28Sell2,3500$21.249.8-25Link
PATRICK GREGORY SVP, CFO
(Click for the stocks that their CFOs have bought)
2015-07-16Sell6,2177,344$20124.3-20.57,344 (Direct)
Schwabe Stefan K.F.Executive Vice President R&D2015-07-13Sell1,950844$19.2337.5-17.32844 (Direct)
Schwabe Stefan K.F.Executive Vice President R&D2015-07-13Sell1,9502,350$19.2337.5-17.322,350 (Direct)
SANDELL SCOTT D10% Owner2015-06-17Sell136,5977,641,250$16.52253.9-3.64
0 (See Note 2)
0 (See Note 3)
7,641,250 (See Note 1)
BASKETT FOREST10% Owner2015-06-17Sell111,8817,641,250$16.391833.7-2.99
0 (See Note 2)
7,641,250 (See Note 1)
BARRIS PETER J10% Owner2015-06-17Sell111,8817,716,055$16.391833.7-2.99
0 (See Note 4)
7,641,250 (See Note 1)
59,849 (See Note 2)
14,956 (See Note 3)
BARRETT M JAMESDirector, 10% Owner2015-06-17Sell111,8817,706,298$16.391833.7-2.9932,524 (Direct)
0 (See Note 5)
7,641,250 (See Note 1)
16,262 (See Note 2)
9,406 (See Note 3)
6,856 (See Note 4)
BARRETT M JAMESDirector, 10% Owner2015-06-16Sell55,1058,739,179$16.85928.5-5.6432,524 (Direct)
7,641,250 (See Note 2)
921,000 (See Note 4)
16,262 (See Note 8)
9,406 (See Note 10)
6,856 (See Note 12)
111,881 (See Note 14)
BARRIS PETER J10% Owner2015-06-16Sell55,1057,827,936$16.85928.5-5.64
7,641,250 (See Note 2)
0 (See Note 4)
59,849 (See Note 7)
14,956 (See Note 9)
111,881 (See Note 11)
BASKETT FOREST10% Owner2015-06-16Sell111,4647,753,131$16.851878.2-5.64
7,641,250 (See Note 2)
0 (See Note 4)
0 (See Note 7)
111,881 (See Note 9)
SANDELL SCOTT D10% Owner2015-06-16Sell95,4377,777,847$16.921614.8-6.03
7,641,250 (See Note 2)
0 (See Note 4)
24,716 (See Note 7)
111,881 (See Note 9)
Schwabe Stefan K.F.Executive Vice President R&D2015-06-12Sell2,0512,794$18.2737.5-12.972,794 (Direct)
Schwabe Stefan K.F.Executive Vice President R&D2015-06-11Sell3,6314,845$16.3959.5-2.994,845 (Direct)
Bryan Jones W.VP of Business Development2015-03-30Sell6,71267,980$12.0280.732.2867,980 (Direct)
Bryan Jones W.VP of Business Development2015-03-24Sell1,90067,980$1222.832.567,980 (Direct)
Bhatt Padmanabh P.Sr. VP of IP; CSO2013-08-19Sell2,28551,806$8.2118.893.6751,806 (Direct)
BIGHAM MICHAELDirector2013-03-22Buy35,00035,000$5.41189.4193.9
5,000 (By Beatrice Emerson Bigham Trust U/A DTD 2/28/2001)
5,000 (By Cabot Forbes Bigham Trust U/A DTD 10/11/1996)
25,000 (By Michael F Bigham CRUT U/A DTD 11/23/1994)
SIEBERT JOHN MDirector2013-03-21Buy3,00015,188$5.516.5189.0915,188 (Direct)
Khattar Jack A.President, CEO
(Click for the stocks that their CEOs have bought)
2013-03-15Buy10,0001,537,058$6.1561.5158.54412,058 (Direct)
1,125,000 (By the KBT Trust)
PATRICK GREGORY SVP, CFO2013-03-14Buy5,0008,903$6.9534.8128.788,903 (Direct)
ORBIMED ADVISORS LLC10% Owner2013-02-13Sell302,1833,000,000$7.552281.5110.6
2,183,000 (See Footnotes(F3,F4,F6))
817,000 (See Footnotes(F3,F5,F6))
ORBIMED ADVISORS LLC10% Owner2012-12-18Sell297,8153,302,183$6.922060.9129.77
0 (See Footnotes(F3,F6))
2,402,600 (See Footnotes(F4,F6))
899,583 (See Footnotes(F5,F6))
SIEBERT JOHN MDirector2012-12-04Buy7,00010,000$8.145795.3310,000 (Direct)
PATRICK GREGORY SVP, CFO2012-05-04Buy3,0003,000$5152183,000 (Direct)
SIEBERT JOHN MDirector2012-05-04Buy3,0003,000$5152183,000 (Direct)
Hudson Frederick M.Director2012-05-04Buy5,0005,000$5252185,000 (Direct)
Khattar Jack A.President, CEO2012-05-04Buy5,0001,527,058$525218402,058 (Direct)
1,125,000 (By the KBT Trust)
Nuerge William A.Director2012-05-04Buy15,00023,750$57521823,750 (Direct)
SHEFFERY MICHAEL BDirector2012-05-04Buy1,100,0005,475,286$55500218
1,668,472 (By OrbiMed Private Investments II, LP)
899,583 (By OrbiMed Private Investments II (QP), LP)
206,816 (By UBS Juniper Crossover Fund, L.L.C.)
2,402,600 (by OrbiMed Private Investments II LP)
297,815 (By UBS Juniper Crossover Fund, L.L.C)
Martin Tami TillotsonVP of Regulatory Affairs2012-05-04Buy2,5002,500$512.52182,500 (Direct)
NEWHALL CHARLES W IIIDirector, 10% Owner2012-05-04Buy4,400,00010,641,250$522000218
10,641,250 (See Note 2)
BARRETT M JAMESDirector, 10% Owner2012-05-04Buy4,400,00010,641,250$522000218
10,641,250 (See Note 2)
NEW ENTERPRISE ASSOCIATES 11 L10% Owner2012-05-04Buy4,400,00010,641,250$52200021810,641,250 (Direct)
ORBIMED ADVISORS LLCDirector, 10% Owner2012-05-04Buy1,100,0003,599,998$55500218
2,402,600 (See Footnotes(F2,F3,F6))
899,583 (See Footnotes(F2,F4,F6))
297,815 (See Footnotes(F2,F5,F6))
Abingworth Management LTD10% Owner2012-05-04Buy1,100,0003,600,000$55500218
3,600,000 (See Notes)

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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