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|Insider||Position||Date||Buy/Sell||Shares||Shares Owned Following This||Trade Price ($)||Cost ($1000)||Price Change
Since Trade (%)
|SANDELL SCOTT D||10% Owner||2013-12-05||Sell||1,000||4,563,512||$5.13||5.1||8.58||Link|
|BARRIS PETER J||10% Owner||2013-12-05||Sell||1,000||4,563,512||$5.13||5.1||8.58||Link|
|BARRETT M JAMES||10% Owner||2013-12-05||Sell||16,000||4,563,512||$5.37||85.9||3.72||Link|
|BARRETT M JAMES||10% Owner||2013-11-21||Sell||5,333||4,564,512||$5.16||27.5||7.95||Link|
|BARRIS PETER J||10% Owner||2013-11-21||Sell||5,333||4,564,512||$5.16||27.5||7.95||Link|
|SANDELL SCOTT D||10% Owner||2013-11-21||Sell||5,333||4,564,512||$5.16||27.5||7.95||Link|
|BROWN JULIA R||Director||2013-05-10||Buy||6,000||6,000||$5.09||30.5||9.43||Link|
|HILL STEPHEN A||President and CEO|
(Click for the stocks that their CEOs have bought)
|HILL STEPHEN A||President and CEO||2013-03-11||Buy||20,000||20,000||$4.43||88.6||25.73||Link|
|BVF PARTNERS L P/IL||10% Owner||2012-11-16||Buy||595,000||349,482||$4||2380||39.25||Link|
|BVF PARTNERS L P/IL||10% Owner||2012-11-16||Buy||1,290,212||349,482||$4.06||5238.3||37.19||Link|
|BVF PARTNERS L P/IL||10% Owner||2012-11-08||Buy||72,429||1,052,258||$4.03||291.9||38.21||Link|
|BVF PARTNERS L P/IL||10% Owner||2012-11-02||Buy||139,700||1,026,058||$4.05||565.8||37.53||Link|
|Richard John P||Director||2012-06-08||Buy||7,500||12,833||$4.16||31.2||33.89||Link|
|Richard John P||Director||2011-07-01||Sell||2,500||5,333||$21.02||52.6||-73.5||Link|
|Musso Alan A||SVP, CFO & Treasurer||2011-06-07||Sell||30,875||2,799||$21.8||673.1||-74.45||Link|
|BROWN JULIA R||Director||2011-05-13||Sell||9,100||0||$23.38||212.8||-76.18||Link|
|Caldwell William S||SVP - Drug Discovery and Dev.||2011-03-31||Sell||2,655||9,735||$26.37||70||-78.88||Link|
Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.
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