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Top Direct Holders

HolderPositionShares% of Shares
Report Date
Dr. Dennis LiottaDirector100,0000.1%2013-11-22
Nicholas J. Simon,IIIN/A51,515less than 0.1%2012-06-04
Dr. Jason S. Fisherman,M.D.Director40,000less than 0.1%2013-11-18
Kurt C. GravesDirector22,709less than 0.1%2012-06-11
Dr. John C. Pottage,Jr,M.D.SVP and Chief Medical Officer12,500less than 0.1%2006-10-25
Mr. Gary E. FrashierDirector5,000less than 0.1%2014-06-16
Gautam Shah,PhDEVP and Chief Compliance Ofc.3,125less than 0.1%2012-12-31
Mr. Christopher A. WhiteN/A2,242less than 0.1%2006-10-31
Dr. Elizabeth A. Olek, D.O.SVP and CMO2,000less than 0.1%2012-01-10

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Fenton Mary KayEVP and CFO
(Click for the stocks that their CFOs have bought)
Deshpande MilindPresident and CEO
(Click for the stocks that their CEOs have bought)
RA CAPITAL MANAGEMENT, LLC2014-09-30Sell1,332,0147,811,000$10.213586.556.08Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-26Sell2,372,91510,229,209$11.1726505.542.52Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-23Sell2,595,07112,672,287$11.2929298.441.01Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-11Sell1,704,36214,695,762$12.4521219.327.87Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-11Sell1,704,36214,695,762$20356.334694504.2-99.92Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-02Sell835,29315,366,014$11.639714.536.89Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-08-27Sell2,711,35218,024,807$11.3330719.640.51Link
Truitt JosephEVP, Chief Commercial Officer2014-08-25Sell25,00025,000$10.82270.547.13Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-08-18Sell4,235,00021,805,285$9.5340359.667.05Link
Deshpande MilindPresident and CEO2014-08-18Sell216,624124,424$102166.259.2Link
KISHBAUCH MICHAEL DDirector2014-08-15Sell495,812158,000$9.44660.669.36Link
FRASHIER GARY EDirector2014-08-13Sell5,00010,000$84099Link
RA CAPITAL MANAGEMENT, LLCSee Footnotes (1)(5)2014-06-20Sell880,00022,486,007$8.4739289.52Link
FRASHIER GARY EDirector2014-06-16Sell55,0000$844099Link
Truitt JosephEVP, Chief Commercial Officer2014-06-16Sell25,0000$7.82195.5103.58Link
QVT Associates GP LLC10% Owner2014-06-16Sell1,819,5518,868,753$7.714010.5106.75Link
FRASHIER GARY EDirector2014-06-16Sell55,00040,000$844099Link
QVT Associates GP LLC10% Owner2014-06-11Sell128,64910,688,304$7.66985.5107.83Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

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