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Top Direct Holders

HolderPositionShares% of Shares
Report Date
Dr. Dennis LiottaDirector100,000less than 0.1%2013-11-22
Nicholas J. Simon,IIIN/A51,515less than 0.1%2012-06-04
Dr. Jason S. Fisherman,M.D.Director40,000less than 0.1%2013-11-18
Kurt C. GravesDirector22,709less than 0.1%2012-06-11
Dr. John C. Pottage,Jr,M.D.SVP and Chief Medical Officer12,500less than 0.1%2006-10-25
Mr. Gary E. FrashierDirector5,000less than 0.1%2014-06-16
Gautam Shah,PhDEVP and Chief Compliance Ofc.3,125less than 0.1%2012-12-31
Mr. Christopher A. WhiteN/A2,242less than 0.1%2006-10-31
Dr. Elizabeth A. Olek, D.O.SVP and CMO2,000less than 0.1%2012-01-10

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Fenton Mary KayEVP and CFO
(Click for the stocks that their CFOs have bought)
Deshpande MilindPresident and CEO
(Click for the stocks that their CEOs have bought)
RA CAPITAL MANAGEMENT, LLC2014-09-30Sell1,332,014$10.213586.5-1.37Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-26Sell2,372,915$11.1726505.5-9.94Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-23Sell2,595,071$11.2929298.4-10.89Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-11Sell1,704,362$12.4521219.3-19.2Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-11Sell1,704,362$20356.334694504.2-99.95Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-09-02Sell835,293$11.639714.5-13.5Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-08-27Sell2,711,352$11.3330719.6-11.21Link
Truitt JosephEVP, Chief Commercial Officer2014-08-25Sell25,000$10.82270.5-7.02Link
RA CAPITAL MANAGEMENT, LLC10% Owner2014-08-18Sell4,235,000$9.5340359.65.56Link
Deshpande MilindPresident and CEO2014-08-18Sell216,624$102166.20.6Link
KISHBAUCH MICHAEL DDirector2014-08-15Sell495,812$9.44660.67.02Link
FRASHIER GARY EDirector2014-08-13Sell5,000$84025.75Link
RA CAPITAL MANAGEMENT, LLCSee Footnotes (1)(5)2014-06-20Sell880,000$8.4739219.76Link
FRASHIER GARY EDirector2014-06-16Sell55,000$844025.75Link
Truitt JosephEVP, Chief Commercial Officer2014-06-16Sell25,000$7.82195.528.64Link
QVT Associates GP LLC10% Owner2014-06-16Sell1,819,551$7.714010.530.65Link
FRASHIER GARY EDirector2014-06-16Sell55,000$844025.75Link
QVT Associates GP LLC10% Owner2014-06-11Sell128,649$7.66985.531.33Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

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