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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Mr. William H. LewisN/A108,9660.37%2010-10-27
Mr. Marc D. BeerN/A78,6310.27%2014-08-28
Mr. Paul G. ThomasN/A36,9780.13%2012-01-03
Dr. Sol J. Barer,PhDN/A29,8900.1%2011-05-05
Dr. Antonio M. Gotto,Jr,M.D.,D.Phil.N/A13,916less than 0.1%2010-10-21
Mr. David I. ScheerN/A10,000less than 0.1%2015-12-01
Mr. Mark J. FitzpatrickN/A9,500less than 0.1%2014-08-19
Dr. William Andrews, M.D.N/A4,660less than 0.1%2015-03-29
Ms. Anne M. VanlentN/A4,000less than 0.1%2014-05-08
Ms. Mary WegerN/A3,038less than 0.1%2015-03-29

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Broadfin Healthcare Master Fun10% Owner2015-11-11Buy40,1004,010,291$10.96439.5-85.044,010,291 (Direct)
Fitzpatrick Mark J.CFO
(Click for the stocks that their CFOs have bought)
2014-08-19Buy1,1509,500$30.6435.2-94.659,500 (Direct)
Beer Marc DCEO
(Click for the stocks that their CEOs have bought)
2014-07-31Buy10,000325,862$33.65336.5-95.1379,400 (Direct)
183,245 (By revocable trust)
55,861 (By grantor retained annuity trust)
7,156 (By Roth IRA)
200 (By son)
Beer Marc DCEO2014-06-03Buy10,000315,862$30.12301.2-94.5669,400 (Direct)
183,245 (By revocable trust)
55,861 (By grantor retained annuity trust)
7,156 (By Roth IRA)
200 (By son)
Beer Marc DCEO2014-05-27Buy10,000305,862$31.59315.9-94.8159,400 (Direct)
183,245 (By revocable trust)
55,861 (By grantor retained annuity trust)
7,156 (By Roth IRA)
200 (By son)
Beer Marc DCEO2014-05-20Buy10,000289,462$30.53305.3-94.6343,000 (Direct)
183,245 (By revocable trust)
55,861 (By grantor retained annuity trust)
7,156 (By Roth IRA)
200 (By son)
Beer Marc DCEO2014-05-08Buy30,000279,462$35.311059.3-95.3633,000 (Direct)
183,245 (By revocable trust)
55,861 (By grantor retained annuity trust)
7,156 (By Roth IRA)
200 (By son)
VANLENT ANNEDirector2014-05-08Buy4,0004,000$33.78135.1-95.154,000 (Direct)
Fraser CraigPres., US/Int. Comm. & Manuf.2014-04-30Sell2,2500$43.5598-96.23Link
Fraser CraigPres., US/Int. Comm. & Manuf.2014-03-31Sell2,2500$46.2104-96.45Link
Sumeray MarkChief Medical Officer2014-03-14Sell2,0000$51.34102.7-96.81Link
Sumeray MarkChief Medical Officer2014-02-14Sell2,0000$63.49127-97.42Link
Fraser CraigPres., US/Int. Comm. & Manuf.2014-02-11Sell2,2500$67150.8-97.55Link
Fitzpatrick Mark J.CFO2014-02-10Sell7,5005,850$62.61469.6-97.385,850 (Direct)
Sumeray MarkChief Medical Officer2014-01-16Sell2,0000$58.63117.3-97.2Link
Fraser CraigPres., US/Int. Comm. & Manuf.2014-01-02Sell2,2500$71.11160-97.69Link
Sumeray MarkChief Medical Officer2014-01-02Sell1,0000$70.9370.9-97.69Link
Sumeray MarkChief Medical Officer2013-12-16Sell2,0000$66.34132.7-97.53Link
Sumeray MarkChief Medical Officer2013-12-02Sell3,0000$70.42211.3-97.67Link
Fraser CraigPres., US/Int. Comm. & Manuf.2013-12-02Sell2,2500$70.41158.4-97.67Link
Sumeray MarkChief Medical Officer2013-11-15Sell2,0000$76.09152.2-97.84Link
Fitzpatrick Mark J.CFO2013-11-11Sell7,5005,850$79.04592.8-97.935,850 (Direct)
Carter Martha J.Chief Regulatory Officer & SVP2013-11-01Sell5,0001,500$82.81414.1-98.021,500 (Direct)
Sumeray MarkChief Medical Officer2013-11-01Sell3,5000$83.28291.5-98.03Link
Fraser CraigPres., US/Int. Comm. & Manuf.2013-11-01Sell2,2500$83.23187.3-98.03Link
Beer Marc DCEO2013-10-30Sell40,000203,082$87.793511.6-98.13195,726 (Direct)
7,156 (By Roth IRA)
200 (By son)
SMITH SANDFORD DDirector2013-10-29Sell2,5020$95237.7-98.27Link
Sumeray MarkChief Medical Officer2013-10-15Sell2,0000$80.33160.7-97.96Link
Fraser CraigPres., US/Int. Comm. & Manuf.2013-10-07Sell20,0000$93.161863.2-98.24Link
Sumeray MarkChief Medical Officer2013-10-07Sell3,5000$93.17326.1-98.24Link
Sumeray MarkChief Medical Officer2013-09-16Sell2,0000$89.77179.5-98.17Link
PERCEPTIVE ADVISORS LLC10% Owner2013-09-05Sell750,00012,743,704$89.266900-98.16
3,473,426 (See Footnotes(F1,F2,F6))
3,573,426 (See Footnotes(F1,F3,F6))
2,873,426 (See Footnotes(F1,F4,F6))
2,823,426 (See Footnotes(F1,F5,F6))
Scheer DavidDirector2013-08-21Sell20,000650,154$84.581691.6-98.0610,000 (Direct)
640,154 (See Footnote)
Sumeray MarkChief Medical Officer2013-08-16Sell2,0000$88.71177.4-98.15Link
Beer Marc DCEO2013-08-15Sell60,000206,417$88.545312.4-98.15199,061 (Direct)
7,156 (By Roth IRA)
200 (By son)
Fitzpatrick Mark J.CFO2013-08-14Sell7,500500$93.44700.8-98.24500 (Direct)
SMITH SANDFORD DDirector2013-08-12Sell10,0000$92.32923.2-98.22Link
Sumeray MarkChief Medical Officer2013-07-15Sell2,0000$78.77157.5-97.92Link
Sumeray MarkChief Medical Officer2013-06-17Sell6,0000$65.27391.6-97.49Link
Sumeray MarkChief Medical Officer2013-05-15Sell6,0000$47.32283.9-96.53Link
Sumeray MarkChief Medical Officer2013-04-22Sell6,0000$40.74244.4-95.97Link
PERCEPTIVE ADVISORS LLC10% Owner2013-02-01Buy50,0003,373,426$27.791389.5-94.1
3,373,426 (See Footnotes(F1,F2,F3))
Carter Martha J.Chief Regulatory Officer & SVP2013-01-23Buy5001,500$27.8113.9-94.11,500 (Direct)
PERCEPTIVE ADVISORS LLC10% Owner2013-01-18Buy50,0003,323,426$27.621381-94.06
3,323,426 (See Footnotes(F1,F2,F3))
PERCEPTIVE ADVISORS LLC10% Owner2013-01-17Buy50,0006,521,852$26.731336.5-93.86
3,248,426 (See Footnotes(F1,F2,F4))
3,273,426 (See Footnotes(F1,F3,F4))
PERCEPTIVE ADVISORS LLC10% Owner2013-01-11Buy475,0006,296,852$27.0712858.3-93.94
3,073,426 (See Footnotes(F1,F2,F3))
3,223,426 (See Footnotes(F1,F3))
PERCEPTIVE ADVISORS LLC10% Owner2012-12-04Buy20,0002,615,293$21.27425.4-92.29
2,615,293 (See Footnotes(F1,F2))
PERCEPTIVE ADVISORS LLC10% Owner2012-11-29Buy30,0002,595,293$22.71681.3-92.78
2,595,293 (SEE FOOTNOTES(F1,F2))
PERCEPTIVE ADVISORS LLC10% Owner2012-11-28Buy150,0002,565,293$21.253187.5-92.28
2,565,293 (SEE FOOTNOTES(F1,F2))
ALTA BIOPHARMA PARTNERS III LP10% Owner2012-10-16Sell200,7332,336,387$18.333679.4-91.052,280,197 (Direct)
56,190 (See footnote)
Carter Martha J.Chief Regulatory Officer2012-03-30Buy1,0001,000$14.0314-88.311,000 (Direct)
Beer Marc DCEO2012-03-29Buy1,000205,417$13.7413.7-88.06198,061 (Direct)
7,156 (by Roth IRA)
200 (by son)
Fitzpatrick Mark J.CFO2012-03-23Buy5000$14.157.1-88.41Link
Beer Marc DCEO2012-03-22Buy1,000204,417$13.9614-88.25197,061 (Direct)
7,156 (by Roth IRA)
200 (By son)
ADVENT INTERNATIONAL CORP/MAMember of Group > 10%2012-03-09Sell100,0002,457,879$15.871587-89.67
2,457,879 (See Footnote)
ADVENT INTERNATIONAL LLCMember of Group > 10%2012-03-09Sell98,8972,430,765$15.871569.5-89.67
2,430,765 (See Footnote)
ADVENT HEALTHCARE & LIFE SCIENMember of Group > 10%2012-03-09Sell40,077985,052$15.87636-89.67985,052 (Direct)
Advent Healthcare & Life ScienMember of Group > 10%2012-03-09Sell58,8201,445,713$15.87933.5-89.671,445,713 (Direct)
AHLS III GP LIMITED PARTNERSHIMember of Group > 10%2012-03-09Sell98,8972,430,765$15.871569.5-89.67
2,430,765 (See Footnote)
Advent Partners HLS III LimiteMember of Group > 10%2012-03-09Sell1,10327,114$15.8717.5-89.6727,114 (Direct)
ADVENT INTERNATIONAL CORP/MAMember of Group > 10%2012-01-31Sell75,0002,557,879$17.141285.5-90.43
2,557,879 (See Footnote)
Advent Healthcare & Life ScienMember of Group > 10%2012-01-31Sell44,1141,504,533$17.14756.1-90.431,504,533 (Direct)
ADVENT HEALTHCARE & LIFE SCIENMember of Group > 10%2012-01-31Sell30,0581,025,129$17.14515.2-90.431,025,129 (Direct)
AHLS III GP LIMITED PARTNERSHIMember of Group > 10%2012-01-31Sell74,1722,529,662$17.141271.3-90.43
2,529,662 (See Footnote)
Advent Partners HLS III LimiteMember of Group > 10%2012-01-31Sell82828,217$17.1414.2-90.4328,217 (Direct)
ADVENT INTERNATIONAL LLCMember of Group > 10%2012-01-31Sell74,1722,529,662$17.141271.3-90.43
2,529,662 (See Footnote)
Index Venture Associates III L10% Owner2012-01-30Sell50,0002,081,827$17.08854-90.4
2,081,827 (See footnote)
Advent Partners HLS III LimiteMember of Group > 10%2011-12-09Sell22429,045$16.893.8-90.2929,045 (Direct)
Advent Healthcare & Life ScienMember of Group > 10%2011-12-09Sell11,9181,548,647$16.89201.3-90.291,548,647 (Direct)
ADVENT HEALTHCARE & LIFE SCIENMember of Group > 10%2011-12-09Sell8,1211,055,187$16.89137.2-90.291,055,187 (Direct)
AHLS III GP LIMITED PARTNERSHIMember of Group > 10%2011-12-09Sell20,0392,603,834$16.89338.5-90.29
2,603,834 (See Footnote)
ADVENT INTERNATIONAL LLCMember of Group > 10%2011-12-09Sell20,0392,603,834$16.89338.5-90.29
2,603,834 (See Footnote)
ADVENT INTERNATIONAL CORP/MAMember of Group > 10%2011-12-09Sell20,2632,632,879$16.89342.2-90.29
2,632,879 (See Footnote)
Advent Partners HLS III LimiteMember of Group > 10%2011-12-06Sell6129,269$16.961-90.3329,269 (Direct)
Advent Healthcare & Life ScienMember of Group > 10%2011-12-06Sell3,2741,560,565$16.9655.5-90.331,560,565 (Direct)
ADVENT HEALTHCARE & LIFE SCIENMember of Group > 10%2011-12-06Sell2,2301,063,308$16.9637.8-90.331,063,308 (Direct)
AHLS III GP LIMITED PARTNERSHIMember of Group > 10%2011-12-06Sell5,5042,623,873$16.9693.3-90.33
2,623,873 (See Footnote)
ADVENT INTERNATIONAL LLCMember of Group > 10%2011-12-06Sell5,5042,623,873$16.9693.3-90.33
2,623,873 (See Footnote)
ADVENT INTERNATIONAL CORP/MAMember of Group > 10%2011-12-06Sell5,5652,653,142$16.9694.4-90.33
2,653,142 (See Footnote)
Beer Marc DCEO2011-09-01Buy6,754197,663$14.7599.6-88.88191,791 (Direct)
5,672 (Roth IRA)
200 (By son)
Beer Marc DCEO2011-08-01Buy6,330239,834$15.7499.6-89.58116,752 (Direct)
123,082 (Roth IRA)
Advent Partners HLS III LimiteMember of Group > 10%2011-07-29Sell5729,330$14.610.8-88.7729,330 (Direct)
Advent Healthcare & Life ScienMember of Group > 10%2011-07-29Sell3,0151,563,839$14.6144-88.771,563,839 (Direct)
ADVENT HEALTHCARE & LIFE SCIENMember of Group > 10%2011-07-29Sell2,0541,065,538$14.6130-88.771,065,538 (Direct)
AHLS III GP LIMITED PARTNERSHIMember of Group > 10%2011-07-29Sell5,0692,629,377$14.6174.1-88.77
2,629,377 (see footnote)
ADVENT INTERNATIONAL LLCMember of Group > 10%2011-07-29Sell5,0692,629,377$14.6174.1-88.77
2,629,377 (see footnote)
ADVENT INTERNATIONAL CORP/MAMember of Group > 10%2011-07-29Sell5,1262,658,707$14.6174.9-88.77
2,658,707 (see footnote)
Index Venture Associates III L10% Owner2011-07-29Sell36,7882,131,827$14.61537.5-88.77
2,131,827 (See footnote)
Ollier MicheleDirector, 10% Owner2011-07-29Sell36,7882,131,827$14.61537.5-88.77
2,131,827 (See footnote)
Advent Partners HLS III LimiteMember of Group > 10%2011-06-29Sell1,34929,387$14.6119.7-88.7729,387 (Direct)
Advent Healthcare & Life ScienMember of Group > 10%2011-06-29Sell71,9231,566,854$14.611050.8-88.771,566,854 (Direct)
ADVENT HEALTHCARE & LIFE SCIENMember of Group > 10%2011-06-29Sell49,0051,067,592$14.61716-88.771,067,592 (Direct)
AHLS III GP LIMITED PARTNERSHIMember of Group > 10%2011-06-29Sell120,9282,634,446$14.611766.8-88.77
2,634,446 (see footnote)
ADVENT INTERNATIONAL LLCMember of Group > 10%2011-06-29Sell120,9282,634,446$14.611766.8-88.77
2,634,446 (see footnote)
ADVENT INTERNATIONAL CORP/MAMember of Group > 10%2011-06-29Sell122,2772,663,833$14.611786.5-88.77
2,663,833 (see footnote)
Index Venture Associates III L10% Owner2011-06-29Sell877,7232,168,435$14.6112823.5-88.77
2,168,435 (See footnote)
Ollier MicheleDirector, 10% Owner2011-06-29Sell877,7232,168,435$14.6112823.5-88.77
2,168,435 (See footnote)
Beer Marc DCEO2011-06-01Buy5,332228,172$18.799.7-91.23111,420 (Direct)
116,752 (Roth IRA)
Beer Marc DCEO2011-04-04Buy5,9570$16.7399.7-90.2Link
Scheer DavidDirector2011-03-11Buy10,0000$15.26152.6-89.25Link
Beer Marc DCEO2010-12-15Buy200210,726$12.332.5-86.7Link
Kiley AlisonDirector, 10% Owner2010-10-27Buy315,7892,680,551$9.53000-82.74Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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