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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Mr. David P. PerryPresident and CEO361,3060.82%2014-03-04
Mr. Paul L. BernsPresident and CEO252,2270.57%2016-01-04
Mr. Geoffrey M. ParkerExecutive Vice President & CFO94,8400.21%2015-03-23
Vincent IppolitoEVP & Chief Commercial Officer70,9850.16%2016-01-19
Paul H. KlingensteinDirector58,0010.13%2010-11-30
Dr. Lee T. Zane, M.D.,M.A.S.SVP and Chief Medical Officer39,081less than 0.1%2016-01-22
Dr. Anders D. Hove,M.D.Director33,886less than 0.1%2015-12-15
Sanjay ChandaSVP, Drug Development29,087less than 0.1%2015-03-04
Ryan T. SullivanSr. VP and General Counsel27,007less than 0.1%2016-01-04
Dr. Kirk R. Maples, PhDSVP, Program Management7,220less than 0.1%2015-06-01

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
IPPOLITO VINCENT PEVP & Chief Commercial Officer2016-01-19Sell20,00070,985$95.411908.2-23.5870,985 (Direct)
Zane LeeSVP and Chief Medical Officer2016-01-15Sell1,46627,281$89.57131.3-18.627,281 (Direct)
IPPOLITO VINCENT PEVP & Chief Commercial Officer2016-01-04Sell85570,985$112.2896-35.0670,985 (Direct)
Sullivan Ryan TSr. VP and General Counsel2016-01-04Sell73327,007$111.7881.9-34.7727,007 (Direct)
BERNS PAUL LPresident and CEO
(Click for the stocks that their CEOs have bought)
2016-01-04Sell2,533252,227$112.35284.6-35.1252,227 (Direct)
Zane LeeSVP and Chief Medical Officer2015-12-15Sell14,00028,747$113.171584.4-35.5728,747 (Direct)
BERNS PAUL LPresident and CEO2015-12-11Sell20,000254,760$117.262345.2-37.82254,760 (Direct)
Sullivan Ryan TSr. VP and General Counsel2015-12-10Sell10,00027,740$110.411104.1-33.9627,740 (Direct)
IPPOLITO VINCENT PEVP & Chief Commercial Officer2015-12-09Sell20,00071,840$107.92158-32.4371,840 (Direct)
BERNS PAUL LPresident and CEO2015-09-15Sell20,000254,760$139.832796.6-47.86254,760 (Direct)
Zane LeeSVP and Chief Medical Officer2015-09-15Sell14,00028,744$139.841957.8-47.8628,744 (Direct)
BERNS PAUL LPresident and CEO2015-08-13Sell20,000254,760$138.692773.8-47.43254,760 (Direct)
Zane LeeSVP and Chief Medical Officer2015-06-15Sell12,00028,156$69.05828.65.5928,156 (Direct)
Maples Kirk RSVP, Program Management2015-06-01Sell6007,220$70.3142.23.77,220 (Direct)
Plattner Jacob jSenior VP, Research2015-05-15Sell8,92022,860$63.73568.514.45,020 (Direct)
17,840 (See Footnote)
Rodriguez Carmen RSnr VP Reg Afrs & Qual. Assur.2015-05-14Sell61,9427,020$62.733885.616.237,020 (Direct)
Maples Kirk RSVP, Program Management2015-05-12Sell6,0607,820$61.07370.119.397,820 (Direct)
Maples Kirk RSVP, Program Management2015-05-01Sell6007,820$53.9532.435.147,820 (Direct)
Sullivan Ryan TSr. VP and General Counsel2015-04-29Sell3,12527,740$53.61167.53627,740 (Direct)
BERNS PAUL LPresident and CEO2015-04-27Sell50,000253,760$63.64318214.57253,760 (Direct)
Plattner Jacob jSenior VP, Research2015-04-15Sell8,92031,780$62.81560.316.085,020 (Direct)
26,760 (See Footnote)
Maples Kirk RSVP, Program Management2015-04-01Sell6008,420$57.0234.227.878,420 (Direct)
Parker Geoffrey M.Executive Vice President & CFO2015-03-23Buy3,000104,840$52.43157.339.0694,840 (Direct)
10,000 (See Footnote)
BERNS PAUL LPresident and CEO2015-03-19Sell37,500308,760$56.072102.630.03308,760 (Direct)
Plattner Jacob jSenior VP, Research2015-03-16Sell8,92040,700$55.649631.135,020 (Direct)
35,680 (See Footnote)
Zane LeeSVP and Chief Medical Officer2015-03-16Sell12,00028,156$56.44677.329.1828,156 (Direct)
Chanda SanjaySVP, Drug Development2015-03-04Sell5,00029,087$4522562.0229,087 (Direct)
IPPOLITO VINCENT PEVP & Chief Commercial Officer2015-03-03Sell9,00070,603$43.88394.966.1670,603 (Direct)
Plattner Jacob jSenior VP, Research2015-03-02Sell6,87549,620$44.02302.665.635,020 (Direct)
44,600 (See Footnote)
Maples Kirk RSVP, Program Management2015-03-02Sell6009,020$43.9526.465.899,020 (Direct)
Plattner Jacob jSenior VP, Research2015-02-02Sell6,87551,475$37.35256.895.21
51,475 (See Footnote)
Maples Kirk RSVP, Program Management2015-02-02Sell6004,600$37.4122.494.894,600 (Direct)
Plattner Jacob jSenior VP, Research2015-01-02Sell6,87558,350$32.09220.6127.2
58,350 (See Footnote)
Maples Kirk RSVP, Program Management2015-01-02Sell6004,200$31.9619.2128.134,200 (Direct)
BERNS PAUL LPresident and CEO2014-12-26Sell25,000325,000$30.82770.5136.57325,000 (Direct)
Shapiro LucyDirector2014-12-12Sell289,68528,000$35.1110170.8107.66
28,000 (MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999)
Zane LeeSVP and Chief Medical Officer2014-12-11Sell4,9007,000$36.09176.8102.027,000 (Direct)
Maples Kirk RSVP, Program Management2014-12-09Sell60,0004,800$36.522191.299.644,800 (Direct)
Maples Kirk RSVP, Program Management2014-12-01Sell6004,800$33.3820118.424,800 (Direct)
Plattner Jacob jSenior VP, Research2014-12-01Sell6,87565,225$33.34229.2118.69
65,225 (See Footnote)
Chanda SanjaySVP, Drug Development2014-11-26Sell5,0003,995$35175108.313,995 (Direct)
Plattner Jacob jSenior VP, Research2014-11-03Sell6,87572,100$29.32201.6148.67
72,100 (See Footnote)
Maples Kirk RSVP, Program Management2014-11-03Sell6005,400$29.117.5150.555,400 (Direct)
Maples Kirk RSVP, Program Management2014-10-01Sell6006,000$23.8514.3205.76,000 (Direct)
Plattner Jacob jSenior VP, Research2014-10-01Sell6,87578,975$24.47168.2197.96
78,975 (See Footnote)
Hove Anders DDirector2014-09-26Sell20,0002,725,535$25500191.64
2,725,535 (By Funds)
Hove Anders DDirector2014-09-19Sell740,0002,745,535$24.8718403.8193.16
2,745,535 (By Funds)
Hove Anders DDirector2014-09-16Sell90,0003,485,535$24.992249.1191.76
3,485,535 (By Funds)
Chanda SanjaySVP, Drug Development2014-09-10Sell10,0003,995$24.25242.5200.663,995 (Direct)
Parker Geoffrey M.Executive Vice President & CFO2014-09-08Buy6,59097,000$21.82143.8234.1487,000 (Direct)
10,000 (See Footnote)
Plattner Jacob jSenior VP, Research2014-09-02Sell6,87585,850$23.34160.5212.38
85,850 (See Footnote)
Maples Kirk RSVP, Program Management2014-09-02Sell33,8796,600$23.3789.4212.926,600 (Direct)
LESCHLY MARKDirector2014-08-27Sell13,0670$22.5294224.04Link
Plattner Jacob jSenior VP, Research2014-08-13Sell6,87592,725$20137.5264.55
92,725 (See Footnote)
Maples Kirk RSVP, Program Management2014-08-13Sell3,9598,294$19.9679265.288,294 (Direct)
Maples Kirk RSVP, Program Management2014-06-04Sell1,6200$14.723.8395.99Link
Maples Kirk RSVP, Program Management2014-05-20Sell1,5001,620$14.1521.2415.271,620 (Direct)
Maples Kirk RSVP, Program Management2014-04-21Sell1,5003,120$15.623.4367.373,120 (Direct)
Parker Geoffrey M.Senior Vice President and CFO2014-03-24Buy5,00096,000$20.11100.6262.5686,000 (Direct)
10,000 (See Footnote)
Shapiro LucyDirector2014-03-21Sell80,000228,664$21.141691.2244.8936,248 (Direct)
192,416 (MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999)
Maples Kirk RSVP, Program Management2014-03-20Sell3,0004,620$22.3967.2225.644,620 (Direct)
Parker Geoffrey M.Senior Vice President and CFO2014-03-18Buy2,41096,000$22.654.5222.6186,000 (Direct)
10,000 (See Footnote)
PERRY DAVID PPresident and CEO2014-03-05Sell65,000361,306$20.221314.3260.58361,306 (Direct)
Maples Kirk RSVP, Program Management2014-02-20Sell3,0007,620$19.3358277.197,620 (Direct)
PERRY DAVID PPresident and CEO2014-02-05Sell15,000426,306$17255328.88426,306 (Direct)
Maples Kirk RSVP, Program Management2014-01-21Sell3,0009,620$20.2760.8259.699,620 (Direct)
PERRY DAVID PPresident and CEO2014-01-09Sell65,000441,306$16.321060.8346.75441,306 (Direct)
Maples Kirk RSVP, Program Management2013-12-20Sell3,00012,620$16.7350.2335.812,620 (Direct)
PERRY DAVID PPresident and CEO2013-12-09Sell40,328506,306$16.23654.5349.23506,306 (Direct)
Parker Geoffrey M.Senior Vice President and CFO2013-11-26Buy10,000251,000$13.4134444.185,000 (Direct)
156,000 (See footnote)
10,000 (Delaware Charter Guarantee & Trust Company, Trustee FBO Mr. Geoffrey Monroe Parker IRA)
Parker Geoffrey M.Senior Vice President and CFO2013-11-25Buy10,000241,000$12.85128.5467.3985,000 (Direct)
146,000 (See footnote)
10,000 (Delaware Charter Guarantee & Trust Company, Trustee FBO Mr. Geoffrey Monroe Parker IRA)
VENROCK ASSOCIATES IV L P10% Owner2013-11-15Sell150,0000$14.062109418.56Link
Hove Anders DDirector, 10% Owner2013-11-15Sell150,0000$14.062109418.56Link
Maples Kirk RSVP, Program Management2013-08-14Sell1,0520$9.7110.2650.88Link
Parker Geoffrey M.Senior Vice President and CFO2013-08-13Buy50,000151,000$8.34417774.225,000 (Direct)
136,000 (See footnote)
10,000 (Delaware Charter Guarantee & Trust Company, Trustee FBO Mr. Geoffrey Monroe Parker IRA)
Parker Geoffrey M.Senior Vice President and CFO2013-06-19Buy23,046100,000$5.2119.81302.124,000 (Direct)
86,000 (See footnote)
10,000 (Delaware Charter Guarantee & Trust Company, Trustee FBO Mr. Geoffrey Monroe Parker IRA)
Parker Geoffrey M.Senior Vice President and CFO2013-06-18Buy20,00076,954$5.22104.41296.744,000 (Direct)
10,000 (Delaware Charter Guarantee & Trust Company, Trustee FBO Mr. Geoffrey Monroe Parker IRA)
62,954 (See footnote)
Maples Kirk RSVP, Program Management2013-06-14Sell5,60052$5.3930.21252.6952 (Direct)
Shapiro LucyDirector2013-04-19Sell25,000308,664$8.02200.5809.136,248 (Direct)
272,416 (MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999)
Shapiro LucyDirector2013-03-22Sell20,000333,664$6.91138.2955.1436,248 (Direct)
297,416 (MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999)
Maples Kirk RSVP, Program Management2012-11-26Sell3,0004,652$5.2215.71296.744,652 (Direct)
Maples Kirk RSVP, Program Management2012-11-01Sell3,0007,652$5.8117.41154.917,652 (Direct)
Shapiro LucyDirector2012-10-05Sell30,000353,664$6.67200.1993.136,248 (Direct)
317,416 (MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999)
Shapiro LucyDirector2012-10-01Sell20,000383,664$6.57131.41009.7436,248 (Direct)
347,416 (MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999)
Shapiro LucyDirector2012-09-26Sell10,000403,664$6.5865.81008.0536,248 (Direct)
367,416 (MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999)
Shapiro LucyDirector2012-09-24Sell20,000413,664$6.33126.61051.8236,248 (Direct)
377,416 (MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999)
Maples Kirk RSVP, Program Management2012-09-24Sell3,00010,652$6.5519.71013.1310,652 (Direct)
VENROCK ASSOCIATES V LP10% Owner2012-09-20Sell19,2730$6.3121.41057.3Link
VENROCK ASSOCIATES IV L P10% Owner2012-09-20Sell19,2730$6.3121.41057.3Link
Hove Anders DDirector, 10% Owner2012-09-20Sell19,2730$6.3121.41057.3Link
VENROCK ASSOCIATES V LP10% Owner2012-09-14Sell35,0000$6.51227.91019.97Link
VENROCK ASSOCIATES IV L P10% Owner2012-09-14Sell35,0000$6.51227.91019.97Link
Hove Anders DDirector, 10% Owner2012-09-14Sell35,0000$6.51227.91019.97Link
VENROCK ASSOCIATES V LP10% Owner2012-09-13Sell25,1770$6.59165.91006.37Link
VENROCK ASSOCIATES IV L P10% Owner2012-09-13Sell25,1770$6.59165.91006.37Link
Hove Anders DDirector, 10% Owner2012-09-13Sell25,1770$6.59165.91006.37Link
Maples Kirk RSVP, Program Management2012-08-27Sell3,00013,652$6.1718.51081.6913,652 (Direct)
Parker Geoffrey M.Senior Vice President and CFO2012-08-22Buy5,00055,954$6.19311077.8755,954 (Direct)
Maples Kirk RSVP, Program Management2012-07-30Sell3,00015,652$6.0318.11109.1215,652 (Direct)
Maples Kirk RSVP, Program Management2012-07-30Sell3,00015,652$6.0318.11109.1215,652 (Direct)
Maples Kirk RSVP, Program Management2012-06-25Sell3,00018,652$5.4416.31240.2618,652 (Direct)
Parker Geoffrey M.Senior Vice President and CFO2012-06-05Buy7,95449,954$4.8138.31415.849,954 (Direct)
Maples Kirk RSVP, Program Management2012-05-29Sell3,00021,652$5.34161265.3621,652 (Direct)
Maples Kirk RSVP, Program Management2012-04-23Sell3,00024,652$5.4616.41235.3524,652 (Direct)
Maples Kirk RSVP, Program Management2012-03-26Sell3,00027,652$6.4519.41030.3927,652 (Direct)
Parker Geoffrey M.Senior Vice President and CFO2012-03-20Buy10,00042,000$6.0860.81099.1842,000 (Direct)
Maples Kirk RSVP, Program Management2012-02-27Sell3,00033,652$5.917.71135.7633,652 (Direct)
Maples Kirk RSVP, Program Management2012-01-30Sell3,00031,652$7.1121.3925.4631,652 (Direct)
Maples Kirk RSVP, Program Management2012-01-10Sell3,00034,652$5.4816.41230.4734,652 (Direct)
Maples Kirk RS.V.P., Program Management2011-12-30Sell10,00037,652$6.1561.51085.5337,652 (Direct)
Maples Kirk RSVP Program Management2011-12-29Sell6,00047,652$6.1436.81087.4647,652 (Direct)
Maples Kirk RS.V.P., Program Management2011-11-28Sell4,00053,652$4.9119.61384.9353,652 (Direct)
Maples Kirk RSVP Program Management2011-10-31Sell4,00057,652$6.6526.6996.3957,652 (Direct)
Maples Kirk RS.V.P., Program Management2011-09-26Sell4,00061,652$5.2220.91296.7461,652 (Direct)
Maples Kirk RS.V.P., Program Management2011-08-29Sell4,00065,652$4.8219.31412.6665,652 (Direct)
Maples Kirk RSVP, Program Management2011-07-25Sell4,00069,652$6.1624.61083.669,652 (Direct)
Maples Kirk RSVP, Program Management2011-06-27Sell4,00073,652$6.425.61039.2273,652 (Direct)
Maples Kirk RSVP, Program Management2011-06-06Sell5,00077,652$6.0530.31105.1277,652 (Direct)
Maples Kirk RSVP, Program Management2011-06-01Sell5,00082,652$6301115.1782,652 (Direct)
Maples Kirk RSVP, Program Management2011-05-25Sell8,36887,652$6.251.91075.9787,652 (Direct)
Parker Geoffrey M.Sr. V.P. & CFO2011-05-24Buy10,00030,000$5.9559.51125.3830,000 (Direct)
Parker Geoffrey M.Senior Vice President and CFO2011-05-10Buy20,00020,000$6.17123.41081.6920,000 (Direct)
Aberdare Ventures II, L.P.10% Owner2010-11-30Buy300,0001,751,936$515001358.2Link
LESCHLY MARKDirector, 10% Owner2010-11-30Buy2,400,0005,621,423$5120001358.2Link
KLINGENSTEIN PAUL HDirector2010-11-30Buy300,0001,809,937$515001358.2Link
RHO VENTURES IV QP LP10% Owner2010-11-30Buy2,400,0005,621,423$5120001358.2Link
VENROCK ASSOCIATES IV L P10% Owner2010-11-30Buy600,0002,625,535$530001358.2Link
Hove Anders DDirector, 10% Owner2010-11-30Buy600,0004,625,535$530001358.2Link
GLAXOSMITHKLINE PLC10% Owner2010-11-24Buy1,000,0002,771,374$550001358.2Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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