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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Harvey J. Berger,M.D.N/A1,732,1110.9%2015-12-31
Jay R. LamarcheN/A552,2050.29%2016-02-01
Edward M. FitzgeraldExecutive VP320,3670.17%2016-03-19
David L. BersteinSVP, Chief IP Counsel262,1150.14%2016-03-19
Dr. Timothy P. Clackson,PhDPresident, R&D, CSO228,7720.12%2016-08-22
Dr. Daniel M. Bollag,PhDSr. VP, Reg. Affairs & Quality166,788less than 0.1%2016-04-29
Mr. Frank HaluskaSVP, Clinical R&D, CMO158,711less than 0.1%2016-04-29
Maria E. CantorSVP, Corporate Affairs144,667less than 0.1%2016-04-29
Dr. John D. Iuliucci,PhDN/A132,742less than 0.1%2009-10-01
Dr. Athanase Lavidas,PhDDirector131,631less than 0.1%2016-06-13

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
CLACKSON TIMOTHY PPresident, R&D, CSO2016-08-22Sell19,436228,772$10.47203.49-2.1228,772 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-08-12Sell25,000248,208$10.5262.5-2.38248,208 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-07-22Sell18,286248,208$8.11148.326.39248,208 (Direct)
Cole Hugh MSVP, Chief Business Officer2016-06-28Sell6,01229,916$7.0542.3845.3929,916 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-06-22Sell23,999264,742$7.28174.7140.8264,742 (Direct)
LAVIDAS ATHANESEDirector2016-06-15Sell76,250131,631$8.21626.0124.85131,631 (Direct)
Radaelli MassimoDirector2016-06-14Sell108,569105,500$8.25895.6924.24105,500 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-05-23Sell17,762288,741$8.08143.5226.86288,741 (Direct)
Panayiotopoulos ParisPresident and CEO
(Click for the stocks that their CEOs have bought)
2016-05-12Buy26,99061,099$7.4120038.3361,099 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-05-02Sell11,700306,503$7.1383.4243.76306,503 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-04-22Sell21,409294,803$7.37157.7839.08294,803 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-03-22Sell23,834316,212$6.58156.8355.78316,212 (Direct)
BERSTEIN DAVID LSVP, Chief IP Counsel2016-03-21Sell2,375262,115$6.4715.3758.42262,115 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2016-03-21Sell4,000155,088$6.4725.8858.42155,088 (Direct)
FITZGERALD EDWARD MExecutive VP2016-03-21Sell5,417320,367$6.4735.0558.42320,367 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2016-03-21Sell3,575147,011$6.4723.1358.42147,011 (Direct)
Duvall Martin JEVP, CCO2016-03-19Sell4,00093,039$6.4725.8858.4293,039 (Direct)
Cantor Maria ESVP, Corporate Affairs2016-03-19Sell3,575135,667$6.4623.0958.67135,667 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-03-19Sell5,417340,046$6.4735.0558.42340,046 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2016-03-03Sell9,625314,951$6.1258.9167.48314,951 (Direct)
BERSTEIN DAVID LSVP, Chief IP Counsel2016-03-03Sell9,625259,740$6.1258.9167.48259,740 (Direct)
Duvall Martin JEVP, CCO2016-03-03Sell9,62589,039$6.1258.9167.4889,039 (Direct)
Cantor Maria ESVP, Corporate Affairs2016-03-03Sell9,625132,742$6.1258.9167.48132,742 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-03-03Sell34,672334,630$6.03209.0769.98334,630 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2016-03-03Sell9,625151,088$6.1158.8167.76151,088 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2016-03-03Sell10,588144,086$6.1164.6967.76144,086 (Direct)
Panayiotopoulos ParisPresident and CEO2016-02-01Buy61,09961,099$4.91300108.7661,099 (Direct)
Duvall Martin JEVP, CCO2016-02-01Sell14,66779,414$4.8170.55113.179,414 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2016-02-01Sell14,667350,052$4.8170.55113.1350,052 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2016-02-01Sell14,667141,463$4.8170.55113.1141,463 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2016-02-01Sell16,133135,424$4.8177.6113.1135,424 (Direct)
BERSTEIN DAVID LSVP, Chief IP Counsel2016-02-01Sell14,667250,115$4.8170.55113.1250,115 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2016-02-01Sell14,667305,326$4.8170.55113.1305,326 (Direct)
Cantor Maria ESVP, Corporate Affairs2016-02-01Sell16,133123,117$4.8277.76112.66123,117 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2015-09-28Sell5,000126,797$6.4632.358.67126,797 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2015-09-28Sell5,000126,797$6.4632.358.67126,797 (Direct)
Duvall Martin JEVP, CCO2015-09-28Sell5,00064,748$6.4632.358.6764,748 (Direct)
Cantor Maria ESVP, Corporate Affairs2015-09-28Sell5,000109,917$6.4732.3558.42109,917 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2015-09-28Sell8,750289,231$6.4656.5358.67289,231 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2015-09-28Sell5,500122,224$6.4635.5358.67122,224 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2015-09-28Sell8,750334,086$6.4656.5358.67334,086 (Direct)
BERSTEIN DAVID LSVP, Chief IP Counsel2015-09-28Sell5,000240,449$6.4632.358.67240,449 (Direct)
BERSTEIN DAVID LSVP, Chief IP Counsel2015-09-28Sell5,000235,449$6.4632.358.67235,449 (Direct)
Cantor Maria ESVP, Corporate Affairs2015-09-01Sell2,696104,917$9.1124.5612.51104,917 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2015-08-28Sell32,858280,481$10328.582.5280,481 (Direct)
Cantor Maria ESVP, Corporate Affairs2015-08-28Sell1,268107,613$1012.682.5107,613 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2015-07-16Sell7,000325,336$8.5459.7820.02325,336 (Direct)
Duvall Martin JEVP, CCO2015-07-16Sell1,40059,748$8.5411.9620.0259,748 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2015-07-16Sell7,000313,339$8.5459.7820.02313,339 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2015-07-16Sell4,000121,797$8.5434.1620.02121,797 (Direct)
Cantor Maria ESVP, Corporate Affairs2015-07-16Sell4,000108,881$8.5434.1620.02108,881 (Direct)
BERSTEIN DAVID LSVP, Chief IP Counsel2015-07-16Sell4,000230,449$8.5434.1620.02230,449 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2015-07-16Sell4,400117,724$8.5437.5820.02117,724 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2015-05-01Sell60,000305,852$8.852816.48305,852 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2015-04-23Sell123,766316,548$9.51175.787.89316,548 (Direct)
BERSTEIN DAVID LSVP, Chief IP Counsel2015-03-23Sell4,375159,907$8.7238.1517.55159,907 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2015-03-23Sell7,000117,797$8.7261.0417.55117,797 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2015-03-23Sell9,584305,209$8.7283.5717.55305,209 (Direct)
Duvall Martin JEVP, CCO2015-03-23Sell4,83454,950$8.842.5416.4854,950 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2015-03-23Sell6,875114,124$8.7159.8817.68114,124 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2015-03-23Sell32,741440,314$8.88290.7415.43440,314 (Direct)
BERSTEIN DAVID LSVP, Chief IP Counsel2015-03-23Sell4,375226,449$8.7238.1517.55226,449 (Direct)
Cantor Maria ESVP, Corporate Affairs and HR2015-03-23Sell16,954104,881$8.86150.2115.69104,881 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2015-03-16Sell34,425110,797$8.62296.7418.91110,797 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2015-02-20Sell49,035428,232$8392.2828.13428,232 (Direct)
BERGER HARVEY J M DChairman & CEO2015-02-12Buy25,0003,608,936$6.83170.7550.071,250,654 (Direct)
1,864,286 (Ocean Capital Partners, Llc)
248,745 (Daughter)
245,251 (Wife)
Cantor Maria ESVP, Corporate Affairs and HR2015-02-02Sell16,134100,129$6.33102.1361.93100,129 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2015-02-02Sell14,667137,722$6.3392.8461.93137,722 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2015-02-02Sell14,667428,232$6.3392.8461.93428,232 (Direct)
Duvall Martin JEVP, CCO2015-02-02Sell14,66750,117$6.3392.8461.9350,117 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2015-02-02Sell14,667295,627$6.3392.8461.93295,627 (Direct)
BERSTEIN DAVID LSVP, Chief IP Counsel2015-02-02Sell14,667222,074$6.3392.8461.93222,074 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2015-02-02Sell16,134108,499$6.33102.1361.93108,499 (Direct)
BERGER HARVEY J M DChairman & CEO2015-01-23Buy25,0003,496,846$6.17154.2566.131,163,564 (Direct)
1,839,286 (Ocean Capital Partners, Llc)
248,745 (Daughter)
245,251 (Wife)
Schlesinger Sarah J.Director2015-01-14Buy2,60028,100$6.6117.1955.0712,500 (Direct)
15,600 (Spouse)
BERGER HARVEY J M DChairman & CEO2014-12-18Buy25,0003,471,846$6.35158.7561.421,163,564 (Direct)
1,814,286 (Ocean Capital Partners, Llc)
248,745 (Daughter)
245,251 (Wife)
Schlesinger Sarah J.Director2014-12-17Buy2,60025,500$6.0915.8368.3112,500 (Direct)
13,000 (Spouse)
Cantor Maria ESVP, Corporate Affairs and HR2014-11-24Sell1,74986,929$712.2446.4386,929 (Direct)
BERGER HARVEY J M DChairman & CEO2014-11-20Buy25,0003,446,846$6.15153.7566.671,163,564 (Direct)
1,789,286 (Ocean Capital Partners, Llc)
248,745 (Daughter)
245,251 (Wife)
Schlesinger Sarah J.Director2014-11-12Buy2,60022,900$6.2616.2863.7412,500 (Direct)
10,400 (Spouse)
BERGER HARVEY J M DChairman & CEO2014-10-16Buy25,0003,421,846$5.2413195.611,163,564 (Direct)
1,764,286 (Ocean Capital Partners, Llc)
248,745 (Daughter)
245,251 (Wife)
Schlesinger Sarah J.Director2014-10-15Buy2,60020,300$5.0513.13102.9712,500 (Direct)
7,800 (Spouse)
Schlesinger Sarah J.Director2014-09-10Buy5,20017,700$5.7329.878.8812,500 (Direct)
5,200 (Spouse)
BERGER HARVEY J M DChairman & CEO2014-09-03Buy25,0003,396,846$6.27156.7563.481,163,564 (Direct)
1,739,286 (Ocean Capital Partners, Llc)
248,745 (Daughter)
245,251 (Wife)
BERGER HARVEY J M DChairman & CEO2014-09-03Buy25,0001,739,286$6.27156.7563.48
1,739,286 (Ocean Capital Partners, Llc)
FITZGERALD EDWARD MExecutive VP, CFO2014-09-02Sell50,000280,960$6.2231164.79280,960 (Direct)
Cantor Maria ESVP, Corporate Affairs and HR2014-09-02Sell2,69688,678$6.2116.7465.0688,678 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2014-09-02Sell56,650123,055$6.22352.3664.79123,055 (Direct)
DENNER ALEXANDER JDirector2014-08-15Buy850,00012,850,000$5.834955.575.81
7,798,665 (Sarissa Capital Domestic Fund LP)
5,051,335 (Sarissa Capital Offshore Master Fund LP)
Cantor Maria ESVP, Corporate Affairs and HR2014-06-02Sell3,71384,461$6.925.6248.5584,461 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2014-04-02Sell3,400104,296$8.2127.9124.85104,296 (Direct)
BERSTEIN DAVID LSVP, GC and Chief IP Officer2014-04-02Sell2,400230,642$8.2219.7324.7230,642 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2014-04-02Sell2,400148,063$8.2219.7324.7148,063 (Direct)
Cantor Maria ESVP, Corporate Affairs and HR2014-04-02Sell4,25088,174$8.2134.8924.8588,174 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2014-04-02Sell6,500403,028$8.2153.3724.85403,028 (Direct)
Cantor Maria ESVP, Corporate Affairs and HR2014-03-21Sell3,66782,379$7.8928.9329.9182,379 (Direct)
BERSTEIN DAVID LSVP, GC and Chief IP Officer2014-03-21Sell1,600227,042$7.8912.6229.91227,042 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2014-03-21Sell2,40099,196$7.8918.9429.9199,196 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2014-03-21Sell2,400144,463$7.8918.9429.91144,463 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2014-03-21Sell6,667394,377$7.8952.629.91394,377 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2013-12-19Sell3,600135,399$5.1518.5499.03135,399 (Direct)
Cantor Maria ESVP, Corporate Affairs2013-12-19Sell6,37574,274$5.1432.7799.4274,274 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2013-12-19Sell5,10091,157$5.1426.2199.4291,157 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2013-12-19Sell4,500221,398$5.1423.1399.42221,398 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2013-12-19Sell9,750380,319$5.1450.1299.42380,319 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2013-09-06Sell8,449370,451$22185.88-53.41370,451 (Direct)
BERGER HARVEY J M DChairman & CEO2013-08-14Sell118,7593,226,041$18.342178.04-44.111,242,759 (Direct)
0 (Trust)
248,745 (Daughter)
1,714,286 (Ocean Capital Partners, Llc)
20,251 (Wife)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2013-07-18Sell6,400129,978$19.79126.66-48.21129,978 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2013-07-18Sell8,000216,898$19.79158.32-48.21216,898 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2013-07-18Sell6,40083,507$19.79126.66-48.2183,507 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2013-07-18Sell6,40067,282$19.79126.66-48.2167,282 (Direct)
0 (Wife)
Keane Raymond TSVP General Counsel & CCO2013-07-18Sell8,00062,096$19.79158.32-48.2162,096 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2013-07-18Sell14,000378,900$19.79277.06-48.21378,900 (Direct)
Cantor Maria ESVP, Corporate Affairs2013-07-18Sell8,00067,724$19.79158.32-48.2167,724 (Direct)
BERGER HARVEY J M DChairman & CEO2013-07-17Sell199,4003,345,000$19.843956.1-48.341,355,861 (Direct)
5,857 (Trust)
248,745 (Daughter)
1,714,286 (Ocean Capital Partners, Llc)
20,251 (Wife)
BERGER HARVEY J M DChairman & CEO2013-06-19Sell11,2003,505,576$18201.6-43.061,511,037 (Direct)
11,257 (Trust)
248,745 (Daughter)
1,714,286 (Ocean Capital Partners, Llc)
20,251 (Wife)
BERGER HARVEY J M DChairman & CEO2013-05-15Sell92,4983,516,776$18.11674.21-43.371,516,837 (Direct)
16,657 (Trust)
248,745 (Daughter)
1,714,286 (Ocean Capital Partners, Llc)
20,251 (Wife)
BERGER HARVEY J M DChairman & CEO2013-04-17Sell105,4003,672,860$18.011898.25-43.091,667,521 (Direct)
22,057 (Trust)
248,745 (Daughter)
1,714,286 (Ocean Capital Partners, Llc)
20,251 (Wife)
Keane Raymond TSVP General Counsel & CCO2013-04-02Sell2,58354,096$18.0546.62-43.2154,096 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2013-04-02Sell3,40073,907$18.0461.34-43.1873,907 (Direct)
Cantor Maria ESVP, Corporate Affairs2013-04-02Sell4,25062,275$18.0476.67-43.1862,275 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2013-04-02Sell6,500363,705$18.04117.26-43.18363,705 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2013-04-02Sell2,40057,682$18.0443.3-43.1857,682 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2013-04-02Sell5,200199,355$18.0493.81-43.18199,355 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2013-04-02Sell2,400208,898$18.0543.32-43.21208,898 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2013-04-02Sell2,400117,871$18.0543.32-43.21117,871 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2013-03-26Sell12,933191,555$18.75242.49-45.33191,555 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2013-03-25Sell19,167357,205$18.87361.68-45.68357,205 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2013-03-25Sell5,33368,807$18.88100.69-45.7168,807 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2013-03-25Sell10,533205,298$18.87198.76-45.68205,298 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2013-03-25Sell12,933114,271$18.87244.05-45.68114,271 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2013-03-25Sell8,13354,082$18.87153.47-45.6854,082 (Direct)
Keane Raymond TSVP General Counsel & CCO2013-03-25Sell13,16751,513$18.87248.46-45.6851,513 (Direct)
Cantor Maria ESVP, Corporate Affairs2013-03-22Sell3,66745,902$19.4571.32-47.345,902 (Direct)
Duvall Martin JSVP, Commercial Operations2013-03-22Sell5762,854$19.5311.25-47.522,854 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2013-03-22Sell6,667338,039$19.46129.74-47.33338,039 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2013-03-22Sell1,600189,498$19.4631.14-47.33189,498 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2013-03-22Sell2,40094,871$19.4646.7-47.3394,871 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2013-03-22Sell2,40060,807$19.4646.7-47.3360,807 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2013-03-22Sell2,40041,882$19.4646.7-47.3341,882 (Direct)
Keane Raymond TSVP General Counsel & CCO2013-03-22Sell2,33438,347$19.4645.42-47.3338,347 (Direct)
BERGER HARVEY J M DChairman & CEO2013-03-13Sell105,4003,686,828$22.052324.07-53.511,676,089 (Direct)
27,457 (Trust)
248,745 (Daughter)
1,714,286 (Ocean Capital Partners, Llc)
20,251 (Wife)
Cantor Maria ESVP, Corporate Affairs2013-03-12Sell2,10538,568$2246.31-53.4138,568 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2013-03-04Sell9,838331,372$21206.6-51.19331,372 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2013-01-02Sell25,000166,543$20.08502-48.95166,543 (Direct)
LAVIDAS ATHANESEDirector2012-12-21Sell10,50080,131$20.31213.26-49.5380,131 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2012-10-01Sell7,50085,519$25187.5-5985,519 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2012-10-01Sell25,000179,767$24.17604.25-57.59179,767 (Direct)
LAMARCHE JAY RDirector2012-10-01Sell10,000507,401$24.99249.9-58.98400,705 (Direct)
6,696 (Wife)
100,000 (By GRAT)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2012-09-19Sell7,50085,519$24180-57.2985,519 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-09-19Sell19,375181,856$24465-57.29181,856 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-09-11Sell19,375189,856$23445.63-55.43189,856 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2012-09-11Sell7,50085,519$23172.5-55.4385,519 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-09-11Sell19,375189,856$23445.63-55.43189,856 (Direct)
Keane Raymond TSVP General Counsel & CCO2012-09-06Sell10,00031,500$22220-53.4131,500 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-09-06Sell19,375197,856$22426.25-53.41197,856 (Direct)
Keane Raymond TSVP General Counsel & CCO2012-09-04Sell7,78031,500$21163.38-51.1931,500 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-09-04Sell16,050205,856$21337.05-51.19205,856 (Direct)
LAMARCHE JAY RDirector2012-08-15Sell20,000525,589$20400-48.75518,893 (Direct)
6,696 (Wife)
Keane Raymond TSVP General Counsel & CCO2012-08-15Sell10,00039,280$20200-48.7539,280 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-08-15Sell36,843234,169$20736.86-48.75234,169 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-08-15Sell8,000213,856$20160-48.75213,856 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2012-07-30Sell28,60033,040$19543.4-46.0533,040 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-07-30Sell8,000221,856$19152-46.05221,856 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-07-30Sell23,234234,169$19441.45-46.05234,169 (Direct)
Keane Raymond TSVP General Counsel & CCO2012-07-30Sell10,00039,280$19190-46.0539,280 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2012-07-30Sell7,50085,519$19142.5-46.0585,519 (Direct)
Cantor Maria ESVP, Corporate Affairs2012-07-30Sell6,47832,848$19123.08-46.0532,848 (Direct)
Keane Raymond TSVP General Counsel & CCO2012-07-26Sell10,00049,280$18180-43.0649,280 (Direct)
LAVIDAS ATHANESEDirector2012-07-20Sell5,00090,631$1890-43.0690,631 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2012-07-02Sell25,000204,767$17.64441-41.89204,767 (Direct)
Cantor Maria ESVP, Corporate Affairs2012-06-25Sell1,76532,337$17.1130.2-40.0932,337 (Direct)
Bollag Daniel MSr. VP, Reg. Affairs & Quality2012-06-22Sell7,50085,095$17.5131.25-41.4385,095 (Direct)
LAVIDAS ATHANESEDirector2012-06-20Sell5,00095,631$17.4187.05-41.1395,631 (Direct)
Cantor Maria ESVP, Corporate Affairs2012-06-19Sell7,50034,102$18135-43.0634,102 (Direct)
LAVIDAS ATHANESEDirector2012-06-05Sell25,000100,631$16.05401.25-36.14100,631 (Direct)
LAVIDAS ATHANESEDirector2012-05-21Sell5,000100,631$16.5482.7-38.03100,631 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2012-05-16Sell22,13036,640$17.5387.28-41.4336,640 (Direct)
0 (Wife)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-05-02Sell20,000233,778$17340-39.71233,778 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2012-05-02Sell3,00049,781$1751-39.7149,781 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-05-02Sell19,375237,856$17329.38-39.71237,856 (Direct)
LAVIDAS ATHANESEDirector2012-04-20Sell10,000105,631$15.06150.6-31.94105,631 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-04-17Sell38,711233,778$14.86575.25-31.02233,778 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2012-04-17Sell40,000169,548$15600-31.67169,548 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2012-04-12Sell17,06258,770$15.39262.58-33.458,770 (Direct)
0 (Wife)
LAVIDAS ATHANESEDirector2012-04-09Sell15,000115,631$15.76236.4-34.96115,631 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-04-03Sell31,261272,489$16.31509.87-37.16272,489 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-04-03Sell2,400245,856$16.1938.86-36.69245,856 (Direct)
Keane Raymond TSVP General Counsel & CCO2012-04-03Sell2,06748,980$16.1933.46-36.6948,980 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2012-04-03Sell5,200167,880$16.1884.14-36.65167,880 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2012-04-03Sell4,25049,781$16.1868.77-36.6549,781 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2012-04-03Sell2,40075,832$16.1838.83-36.6575,832 (Direct)
0 (Wife)
DODION PIERRE FSVP, Corp. Dev. & Operations2012-04-02Sell10,66775,832$16.11171.85-36.3775,832 (Direct)
0 (Wife)
Cantor Maria ESVP, Corporate Affairs2012-03-27Sell24,00028,227$16.17388.08-36.6128,227 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-03-26Sell7,500290,750$16120-35.94290,750 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-03-26Sell11,375242,256$16182-35.94242,256 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2012-03-26Sell25,00072,232$16.5412.5-37.8872,232 (Direct)
0 (Wife)
Haluska FrankSVP, Clinical R&D, CMO2012-03-26Sell3,00045,531$1648-35.9445,531 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-03-26Sell34,075229,856$16.42559.51-37.58229,856 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2012-03-23Sell6,66745,531$15.41102.74-33.4845,531 (Direct)
Keane Raymond TSVP General Counsel & CCO2012-03-23Sell10,53345,880$15.41162.31-33.4845,880 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2012-03-23Sell24,90172,232$15.29380.74-32.9672,232 (Direct)
0 (Wife)
FITZGERALD EDWARD MExecutive VP, CFO2012-03-23Sell12,933160,080$15.41199.3-33.48160,080 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-03-23Sell15,333290,750$15.41236.28-33.48290,750 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-03-23Sell10,533242,256$15.41162.31-33.48242,256 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-03-20Sell18,800226,456$15.02282.38-31.76226,456 (Direct)
Keane Raymond TSVP General Counsel & CCO2012-03-20Sell8,40030,380$15.02126.17-31.7630,380 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2012-03-20Sell15,00038,865$15.02225.3-31.7638,865 (Direct)
FITZGERALD EDWARD MExecutive VP, CFO2012-03-20Sell31,200140,680$15.02468.62-31.76140,680 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2012-03-20Sell12,98076,800$15.01194.83-31.7176,800 (Direct)
0 (Wife)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-03-20Sell36,400267,750$15.02546.73-31.76267,750 (Direct)
Cantor Maria ESVP, Corporate Affairs2012-03-20Sell14,00028,277$15.02210.28-31.7628,277 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-02-28Sell11,375198,256$15.5176.31-33.87198,256 (Direct)
DODION PIERRE FSVP, Corp. Dev. & Operations2012-02-23Sell25,00030,780$15375-31.6730,780 (Direct)
0 (Wife)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-02-23Sell4,100198,256$1561.5-31.67198,256 (Direct)
Haluska FrankSVP, Clinical R&D, CMO2012-02-21Sell4,50023,865$14.5165.3-29.3623,865 (Direct)
BERSTEIN DAVID LSenior VP, Chief IP Officer2012-02-21Sell35,100202,356$14.5508.95-29.31202,356 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-02-14Sell76,436119,882$15.121155.71-32.21119,882 (Direct)
Keane Raymond TSVP General Counsel & CCO2012-02-14Sell12,50017,780$15.13189.13-32.2517,780 (Direct)
CLACKSON TIMOTHY PPresident, R&D, CSO2012-02-14Sell16,500121,650$15.5255.75-33.87121,650 (Direct)
LAMARCHE JAY RDirector2012-01-27Sell26,900525,589$15.05404.85-31.89518,893 (Direct)
6,696 (Wife)
LAMARCHE JAY RDirector2012-01-26Sell3,100534,130$15.0446.62-31.85527,434 (Direct)
6,696 (Wife)
LAMARCHE JAY RDirector2011-03-25Sell25,0000$7.01175.2546.22Link
LAMARCHE JAY RDirector2011-02-02Sell25,000552,599$6.4816258.18545,903 (Direct)
6,696 (Wife)
LAMARCHE JAY RDirector2011-01-11Sell25,000557,599$5.5137.586.36Link
LAMARCHE JAY RDirector2011-01-11Sell25,000550,903$5.51137.7586.03Link
LAMARCHE JAY RDirector2010-12-20Sell25,000582,599$5125105Link
Bollag Daniel MSr. VP, Reg. Affairs & Quality2010-10-26Buy3,0003,000$3.711.1177.03Link
CLACKSON TIMOTHY PPres., R & D., Chief Sci. Off.2010-10-26Buy10,000117,437$3.737177.03Link
Keane Raymond TSVP General Counsel & CCO2010-05-17Sell10,2560$4.0941.95150.61Link
DODION PIERRE FSenior VP, Chief Medical Off2010-05-12Sell19,2920$4.2982.76138.93Link
IULIUCCI JOHN DSenior VP, Development2009-10-01Sell70,000132,742$2.16151.2374.54Link
BERGER HARVEY J M DChairman & CEO2009-08-04Buy1,714,2861,714,286$1.753000485.71Link
DODION PIERRE FSenior VP, Chief Medical Off2009-08-04Buy5,7145,714$1.7510485.71Link
LAMARCHE JAY RDirector2006-02-15Sell26,077377,029$6.52170.0257.21Link
SOBEL BURTON EDirector2006-01-18Sell4,1470$6.526.9657.69Link
SOBEL BURTON EDirector2006-01-09Sell5,8534,147$6.538.0457.69Link
SOBEL BURTON EDirector2004-09-20Sell10,0000$6.1361.367.21Link
BERSTEIN DAVID LSenior VP Chief Patent Counsel2003-09-24Sell32,14312,182$722546.43Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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