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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Jack LiefN/A622,1890.26%2015-03-03
Dr. Dominic P. Behan,PhDN/A508,0000.21%2014-12-15
Dr. Derek T. Chalmers,PhDN/A370,6670.15%2004-06-11
Dr. Harry F. Hixson, JrN/A148,405less than 0.1%2015-06-12
Donald D. BelcherN/A134,257less than 0.1%2015-06-12
Steven W. Spector,J.D.N/A128,039less than 0.1%2015-03-17
Mr. Phillip M. SchneiderN/A94,257less than 0.1%2015-06-12
Scott H. BiceN/A89,157less than 0.1%2015-06-12
Dr. Christine A. White,M.D.Director85,529less than 0.1%2016-06-13
Randall E. WoodsN/A85,257less than 0.1%2015-06-12

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
White Christine AnnaDirector2016-06-13Sell18,72885,529$1.9937.27-15.5885,529 (Direct)
WOODS RANDALL EDirector2015-03-30Sell76,26845,112$4.49342.44-62.5845,112 (Direct)
SPECTOR STEVEN WEVP, General Counsel & Sec2015-03-17Sell70,000128,039$5350-66.4128,039 (Direct)
SPECTOR STEVEN WEVP, General Counsel & Sec2015-01-08Sell45,000128,039$6.26281.7-73.16128,039 (Direct)
SHANAHAN WILLIAM R JRSVP & Chief Medical Officer2015-01-07Sell50,00050,000$5.49274.5-69.450,000 (Direct)
LIEF JACKChairman, President and CEO
(Click for the stocks that their CEOs have bought)
2014-07-01Sell223,525361,039$5.851307.62-71.28361,039 (Direct)
BELCHER DONALD DDirector2014-06-27Sell2,47394,112$5.8514.47-71.2894,112 (Direct)
SPECTOR STEVEN WEVP, General Counsel & Sec2014-05-12Sell45,000102,187$7.05317.25-76.17102,187 (Direct)
BELCHER DONALD DDirector2014-05-06Sell4,17668,728$729.23-7668,728 (Direct)
HIXSON HARRY F JRDirector2014-04-22Sell36,90082,876$6.31232.84-73.3882,876 (Direct)
Nova Tina SusanDirector2014-04-14Sell35,00018,728$6.22217.7-72.9918,728 (Direct)
SHANAHAN WILLIAM R JRSVP & Chief Medical Officer2014-04-01Sell60,00035,000$6.37382.2-73.6335,000 (Direct)
BELCHER DONALD DDirector2014-04-01Sell1,90568,728$6.4512.29-73.9568,728 (Direct)
SPECTOR STEVEN WEVP, General Counsel & Sec2014-03-04Sell25,000101,794$7.01175.25-76.03101,794 (Direct)
LIEF JACKChairman, President and CEO2014-01-17Sell100,000583,704$7.81781-78.49583,704 (Direct)
BEHAN DOMINIC PEVP & Chief Scientific Officer2014-01-10Sell33,332483,000$6.25208.33-73.12483,000 (Direct)
BICE SCOTT HDirector2014-01-09Sell25,00023,628$6.1152.5-72.4623,628 (Direct)
BELCHER DONALD DDirector2014-01-09Sell30,00068,728$6.15184.5-72.6868,728 (Direct)
SPECTOR STEVEN WEVP, General Counsel & Sec2014-01-09Sell33,334101,794$6.1203.34-72.46101,794 (Direct)
SPECTOR STEVEN WEVP, General Counsel & Sec2013-11-12Sell20,00071,420$5.19103.8-67.6371,420 (Direct)
BEHAN DOMINIC PEVP & Chief Scientific Officer2013-09-10Sell200,000453,000$6.311262-73.38453,000 (Direct)
SPECTOR STEVEN WEVP, General Counsel & Sec2013-09-05Sell20,00071,046$6.54130.8-74.3171,046 (Direct)
Audet Craig MichaelSVP, Opn & Head Glob Reg Afrs2013-05-21Sell83,75015,000$8670-7915,000 (Direct)
HOFFMAN ROBERTSVP, Finance and CFO2013-04-01Sell71,25019,570$8.21584.96-79.5419,570 (Direct)
HOFFMAN ROBERTSVP, Finance and CFO2012-10-01Sell50,0003,382$8.32416-79.813,382 (Direct)
HOFFMAN ROBERTSVP, Finance and CFO2012-07-05Sell10,0002,763$11110-84.732,763 (Direct)
SPECTOR STEVEN WEVP, General Counsel & Sec2012-07-03Sell156,66539,588$9.991565.08-83.1839,588 (Direct)
Bielasz Jennifer KathleenSr.Dir. of Acct. & Cont. (PAO)2012-03-29Sell10,8004,830$3.0332.72-44.554,800 (Direct)
30 (By son)
Bielasz Jennifer KathleenSr.Dir. of Acct. & Cont. (PAO)2012-02-01Buy308,755$1.90.06-11.588,725 (Direct)
30 (By son)
White Christine AnnaDirector2009-05-14Buy20,00020,000$2.6753.4-37.08
HIXSON HARRY F JRDirector2009-05-14Buy60,00090,000$2.67160.2-37.08
WOODS RANDALL EDirector2009-05-14Buy1,0001,000$2.752.75-38.91
BICE SCOTT HDirector2009-05-14Buy3,8004,900$2.6710.15-37.08
BELCHER DONALD DDirector2009-05-14Buy35,00050,000$2.6291.7-35.88
LAFORCE JAMESDirector2009-05-14Buy3,50013,500$2.749.59-38.69
HOFFMAN ROBERTVP, Finance and CFO2008-09-02Sell10,00057,254$6.1661.6-72.73
HIXSON HARRY F JRDirector2008-06-10Buy20,00030,000$4.6993.8-64.18
SCHNEIDER PHILLIP MDirector2008-05-21Buy10,00010,000$5.0450.4-66.67
BELCHER DONALD DDirector2008-05-13Buy10,00015,000$5.1851.8-67.57
LAFORCE JAMESDirector2008-05-13Buy10,00010,000$5.1851.8-67.57
2007-10-19Sell25,0003,238,908$10.51262.75-84.02
SPECTOR STEVEN WSVP, General Counsel & Sec2007-10-01Sell10,00053,852$11110-84.73
SCOTTI LOUIS JVP, Marketing and Business Dev2007-09-26Sell5,00027,324$11.5957.95-85.5
BEHAN DOMINIC PSVP & Chief Scientific Officer2007-03-15Sell58,552317,500$11.2655.78-85
SCOTTI LOUIS JVP, Marketing and Business Dev2007-03-14Sell5,00031,757$11.3256.6-85.16
SCOTTI LOUIS JVP, Marketing and Business Dev2006-08-01Sell10,00036,757$10.37103.7-83.8Link
HOFFMAN ROBERTVP, Finance and CFO2006-07-31Sell7,50066,714$10.4678.45-83.94Link
AJIT-SIMH K AVP, Quality Systems2006-03-06Sell10,0001,179$19.38193.8-91.33Link
BICE SCOTT HDirector2005-09-26Buy1,1001,100$8.989.88-81.29Link
HIXSON HARRY F JRDirector2005-09-21Buy10,00010,000$8.9689.6-81.25Link
BVF PARTNERS L P/IL2004-07-08Sell828,088994,851$5.14223.25-67.06Link
BVF PARTNERS L P/IL2004-07-01Sell95,0001,395,351$5.42514.9-69Link
BVF PARTNERS L P/IL2004-06-29Sell71,0001,441,351$5.31377.01-68.36Link
BVF PARTNERS L P/IL2004-06-28Sell54,0002,955,702$5.31286.74-68.36Link
BVF PARTNERS L P/IL2004-06-18Sell6,0001,502,351$5.5233.12-69.57Link
BVF PARTNERS L P/IL2004-06-16Sell104,0001,505,351$5.4561.6-68.89Link
BELCHER DONALD DDirector2004-03-23Buy5,0005,000$6.331.5-73.33Link
SCOTTI LOUIS JVP, Marketing and Business Dev2004-03-22Sell15,00046,757$6.496-73.75Link
BVF PARTNERS L P/IL2004-01-21Sell144,5002,492,328$6867-72Link
BVF PARTNERS L P/IL2004-01-14Sell95,0002,592,328$6.05574.75-72.23Link
BVF PARTNERS L P/IL2004-01-09Sell24,0002,668,328$6.3151.2-73.33Link
BVF PARTNERS L P/IL2003-12-31Sell1,187,0002,687,328$6.27359.4-72.9Link
BVF PARTNERS L P/IL2003-10-17Sell2,911,0003,636,328$7.6922385.59-78.15Link
LAMPERT MARK NDirector, 10% Owner2003-10-17Sell2,911,0004,520,212$7.6922385.59-78.15Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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