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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
LEFKOFF KYLEDirector2017-03-31Sell45,00051,585$8.92401.4-1.236,585 (Direct)
45,000 (See footnote(F2,))
BAUM CHARLES MDirector2017-03-28Sell25,0005,000$9.27231.75-4.965,000 (Direct)
Redmile Group, LLC10% Owner2016-09-28Sell2,492,57816,658,072$6.3615852.838.52
16,658,072 (See Footnote(F2,))
Redmile Group, LLC10% Owner2016-09-15Sell400,00019,150,650$3.51400151.71
19,150,650 (See footnote(F5,))
Redmile Group, LLC10% Owner2016-09-15Buy400,00019,150,650$3.511404151
19,150,650 (See footnote(F5,))
Redmile Group, LLC10% Owner2016-01-20Buy300,00019,150,650$3.19957176.18
19,150,650 (See footnote)
Redmile Group, LLC10% Owner2016-01-12Buy75,00018,850,650$3.6270144.72
18,850,650 (See Footnote)
Redmile Group, LLC10% Owner2016-01-11Buy925,00018,775,650$3.673394.75140.05
18,775,650 (See footnote)
Redmile Group, LLC10% Owner2015-10-01Buy600,14017,850,650$4.582748.6492.36
17,850,650 (See footnote)
Redmile Group, LLC10% Owner2015-10-01Buy782,59218,033,102$4.583584.2792.36
18,033,102 (See footnote)
Redmile Group, LLC10% Owner2015-08-26Buy49,90017,250,510$5.48273.4560.77
17,250,510 (See footnote)
Redmile Group, LLC10% Owner2015-08-25Buy790,00017,200,610$5.384250.263.75
17,200,610 (See Footnote)
Redmile Group, LLC10% Owner2015-08-12Buy532,50032,616,220$5.883131.149.83
16,205,610 (See footnote)
16,410,610 (See Footnote)
Redmile Group, LLC10% Owner2015-08-10Buy1,048,99315,878,110$5.86084.1651.9
15,878,110 (See footnote)
BAUM CHARLES MDirector2015-05-08Sell25,0000$7.38184.519.38Link
LEFKOFF KYLEDirector2015-03-03Sell70,00048,585$856010.133,585 (Direct)
45,000 (See footnote)
Robbins Andrews RSVP, Commercial Operations2015-03-02Sell21,5760$8.251786.79Link
Squarer RonCEO
(Click for the stocks that their CEOs have bought)
2015-03-02Sell40,00012,927$8.253306.7912,927 (Direct)
MOORE JOHN RVP, General Counsel2013-11-29Sell11,66620$5.7967.5552.1620 (Direct)
MOORE JOHN RVP, General Counsel2013-11-13Sell20011,686$5.791.1652.1611,686 (Direct)
Ratcliffe LiamDirector2013-09-27Sell1,125,7280$66754.3746.83
0 (See footnote)
Ratcliffe LiamDirector2013-09-16Sell1,673,1721,125,728$6.0810172.8944.9
1,125,728 (See footnote)
Ratcliffe LiamDirector2013-09-06Sell577,2862,798,900$5.793342.4952.16
2,798,900 (See footnote)
MOORE JOHN RVP, General Counsel2013-08-02Sell75,38411,886$7.02529.225.511,886 (Direct)
MOORE JOHN RVP, General Counsel2013-07-23Sell5,00016,645$6.532.535.5416,645 (Direct)
MOORE JOHN RVP, General Counsel2012-10-08Sell28,54711,886$5.69162.4354.8311,886 (Direct)
0 (Held by spouse)
CARRUTHERS MICHAELCFO2012-02-10Sell1,54594,570$2.654.09232.4594,570 (Direct)
CARRUTHERS MICHAELCFO2012-01-12Sell1,99496,115$2.064.11327.6796,115 (Direct)
CARRUTHERS MICHAELCFO2011-12-12Sell1,74396,295$2.354.1274.8996,295 (Direct)
BVF PARTNERS L P/IL10% Owner2011-12-05Buy183,8535,938,900$2.11387.93317.54
4,893,000 (See Explanation of Responses)
1,045,900 (See Explanation of Respones)
CARRUTHERS MICHAELCFO2011-11-11Sell1,65698,038$2.474.09256.6898,038 (Direct)
CARRUTHERS MICHAELCFO2011-10-12Sell1,97799,694$2.084.11323.5699,694 (Direct)
CARRUTHERS MICHAELCFO2011-09-12Sell2,03476,978$2.024.11336.1476,978 (Direct)
CARUTHERS MARVIN HDirector2011-08-16Sell2,300446,934$2.144.92311.68177,763 (Direct)
269,040 (Held by GRAT)
131 (Held in Family LLC; disclaimed by Reporting Person)
CARRUTHERS MICHAELCFO2011-08-12Sell1,81079,012$2.264.09289.8279,012 (Direct)
LEFKOFF KYLEDirector2011-08-11Buy5,00049,585$2.2211.1296.8510,000 (Direct)
15,000 (In 401k Profit Sharing Plan)
24,585 (Held as custodian for UTMA for benefit of minor children)
CARRUTHERS MICHAELCFO2011-07-12Sell1,63880,822$2.54.1252.480,822 (Direct)
CONWAY ROBERTCEO2011-06-17Buy25,000656,196$2.1754.25305.99576,196 (Direct)
80,000 (Held by spouse as custodian for UTMA for benefit of minor children)
CARRUTHERS MICHAELCFO2011-06-10Sell1,72082,460$2.384.09270.1782,460 (Direct)
CONWAY ROBERTCEO2011-05-13Buy20,000631,196$2.8657.2208.04551,196 (Direct)
80,000 (Held by spouse as custodian for UTMA for benefit of minor children)
CARRUTHERS MICHAELCFO2011-05-12Sell1,48484,180$2.754.08220.3684,180 (Direct)
CARRUTHERS MICHAELCFO2011-04-12Sell1,3400$3.044.07189.8Link
MOORE JOHN RVP, General Counsel2011-04-05Sell3560$3.31.17166.97Link
CARRUTHERS MICHAELCFO2011-03-11Sell1,3100$3.114.07183.28Link
CARRUTHERS MICHAELCFO2011-02-11Sell1,4030$2.914.08202.75Link
CARRUTHERS MICHAELCFO2011-01-12Sell1,27289,717$3.24.07175.31Link
MOORE JOHN RVP, General Counsel2011-01-11Sell2,959356$3.39.76166.97Link
MOORE JOHN RVP, General Counsel2011-01-06Sell24,0393,315$3.2578.13171.08Link
CARRUTHERS MICHAELCFO2010-12-10Sell1,25689,650$3.244.07171.91Link
LEFKOFF KYLEDirector2010-11-18Sell10,00044,585$3.2732.7169.42Link
CARRUTHERS MICHAELCFO2010-11-12Sell1,22090,906$3.334.06164.56Link
CARRUTHERS MICHAELCFO2010-10-12Sell1,22592,126$3.324.07165.36Link
MOORE JOHN RVP, General Counsel2010-10-05Sell20,06727,354$3.2966.02167.78Link
CARRUTHERS MICHAELCFO2010-09-14Sell1,41570,353$2.884.08205.9Link
CARRUTHERS MICHAELCFO2010-08-23Sell1771,768$2.790.05215.77Link
MOORE JOHN RVP, General Counsel2010-08-03Sell6,31921,317$3.2520.54171.08Link
CARRUTHERS MICHAELCFO2010-07-23Sell1,30971,785$3.114.07183.28Link
CARRUTHERS MICHAELCFO2010-06-23Sell1,20873,094$3.374.07161.42Link
CARUTHERS MARVIN HDirector2010-06-08Sell1,650449,234$3.125.15182.37Link
CARRUTHERS MICHAELCFO2010-05-21Sell1,18374,302$3.444.07156.1Link
LEFKOFF KYLEDirector2010-05-07Buy4,00054,585$3.7114.84137.47Link
CARRUTHERS MICHAELCFO2010-04-23Sell1,07475,485$3.784.06133.07Link
CARRUTHERS MICHAELCFO2010-03-23Sell1,66176,559$2.464.09258.13Link
CARRUTHERS MICHAELCFO2010-02-23Sell1,70778,220$2.44.1267.08Link
CARRUTHERS MICHAELCFO2010-02-05Sell6,28679,927$2.4415.34261.07Link
CARRUTHERS MICHAELCFO2010-01-22Sell1,64486,213$2.494.09253.82Link
CARRUTHERS MICHAELCFO2010-01-06Sell5,68186,706$2.6915.28227.51Link
CARRUTHERS MICHAELCFO2009-12-23Sell1,53394,432$2.664.08231.2Link
CARRUTHERS MICHAELCFO2009-11-23Sell2,04593,920$2.014.11338.31Link
CARRUTHERS MICHAELCFO2009-10-23Sell2,04995,965$2.014.12338.31Link
CARRUTHERS MICHAELCFO2009-09-25Sell1,31579,308$2.773.64218.05Link
CARRUTHERS MICHAELCFO2009-08-24Sell88280,623$4.173.68111.27Link
CARRUTHERS MICHAELCFO2009-07-30Sell92580,738$3.953.65123.04Link
CARRUTHERS MICHAELCFO2009-06-22Sell1,17081,663$3.063.58187.91
CARRUTHERS MICHAELCFO2009-05-26Sell1,17082,833$3.133.66181.47
LEFKOFF KYLEDirector2008-11-13Buy3,0006,000$3.289.84168.6
LEFKOFF KYLEDirector2008-03-10Buy3,0003,000$5.3916.1763.45
WILLIAMS DOUGLAS EDirector2008-03-06Buy2,5002,500$6.1615.443.02
ZABRISKIE JOHN LDirector2008-03-05Buy30,00030,000$6.37191.138.3
CARRUTHERS MICHAELCFO2007-09-19Sell10,00040,812$13130-32.23
VAN LUNSEN GIL JDirector2007-08-09Sell12,0005,260$11.47137.64-23.19
KOCH KEVINPresident & CSO2007-02-05Sell20,000555,354$14.05281-37.3
KOCH KEVINPresident & CSO2007-01-19Sell26,900575,354$14376.6-37.07
MOORE JOHN RVP, General Counsel2006-11-20Sell27,2630$13.04355.51-32.44
CONWAY ROBERTCEO2006-11-15Sell50,000243,241$12.5625-29.52
CARRUTHERS MICHAELCFO2006-11-13Sell14,87030,449$11.98178.14-26.46
LEFKOFF KYLEDirector2006-11-09Sell51,0001,000$11.7596.7-24.7
CARRUTHERS MICHAELCFO2006-11-08Sell10,00045,319$10.85108.5-18.8
CONWAY ROBERTCEO2006-11-03Sell100,000193,241$10.011001-11.99
CARRUTHERS MICHAELCFO2006-10-27Sell5,00055,319$9.9549.75-11.46
CARRUTHERS MICHAELCFO2006-03-07Sell5,00060,449$9.4947.45-7.17Link
LEFKOFF KYLEDirector2006-02-21Sell11,00089,135$9.0299.22-2.33Link
KOCH KEVINPresident & CSO2006-02-17Sell20,000744,540$9.38187.6-6.08Link
MOORE JOHN RVP, General Counsel2006-02-17Sell4,4562,252$9.3841.8-6.08Link
CARRUTHERS MICHAELCFO2006-02-17Sell10,00065,449$8.7487.40.8Link
CARRUTHERS MICHAELCFO2006-02-13Sell8,90975,449$8.1672.77.97Link
CARRUTHERS MICHAELCHIEF FINANCIAL OFFICER2005-06-17Sell5,00084,243$6.1530.7543.25Link
CARRUTHERS MICHAELCHIEF FINANCIAL OFFICER2005-03-31Sell5,00084,072$6.9234.627.31Link
VAN LUNSEN GIL JDirector2005-03-24Buy1,3153,260$7.479.8217.94Link
PISCOPIO TONYVice President, Chemistry2004-04-29Sell5,000553,527$11.4757.35-23.19Link
PISCOPIO TONYVice President, Chemistry2004-04-28Sell5,000558,527$10.9554.75-19.54Link
PISCOPIO TONYVP/Dir of Chemistry2004-04-27Sell29,500563,527$6.7197.6531.49Link
PISCOPIO TONYVP Chem,Dir Proc. Chem2004-04-23Sell10,000593,027$9.0990.9-3.08Link
PISCOPIO TONYVice President, Chemistry2004-04-21Sell5,000603,027$9.1545.75-3.72Link
PISCOPIO TONYVice President, Chemistry2004-04-20Sell5,000608,027$945-2.11Link
PISCOPIO TONYVice President, Chemistry2004-04-19Sell5,000613,027$8.6443.21.97Link
PISCOPIO TONYVice President, Chemistry2004-04-16Sell5,000618,027$8.5842.92.68Link
PISCOPIO TONYVice President, Chemistry2004-04-15Sell5,000623,027$8.6843.41.5Link
PISCOPIO TONYVice President, Chemistry2004-04-14Sell5,000628,027$8.3441.75.64Link
PISCOPIO TONYVice President, Chemistry2004-04-13Sell5,000633,027$8.7543.750.69Link
PISCOPIO TONYVice President, Chemistry2004-04-12Sell5,000638,027$8.4642.34.14Link
PISCOPIO TONYVice President, Chemistry2004-04-08Sell5,000643,027$945-2.11Link
PISCOPIO TONYVice President, Chemistry2004-04-07Sell5,000648,027$9.145.5-3.19Link
PISCOPIO TONYVice President, Chemistry2004-04-06Sell5,000653,027$9.3546.75-5.78Link
PISCOPIO TONYVice President, Chemistry2004-04-05Sell5,000658,027$8.8644.3-0.56Link
PISCOPIO TONYVP of Chemistry2004-04-02Sell10,000663,027$8.9689.6-1.67Link
CARRUTHERS MICHAELCHIEF FINANCIAL OFFICER2004-02-26Sell14,00088,973$7.51105.1417.31Link
VAN LUNSEN GIL JDirector2003-11-10Buy5801,945$52.976.2Link
BVF PARTNERS L P/IL2003-11-05Sell3,865,0350$519325.1876.2Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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