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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Kevin Koch, PhDPresident & CSO786,9170.55%2013-07-24
Mr. Robert E. ConwayCEO633,3860.45%2011-10-04
Dr. Anthony D. Piscopio,PhDVice President, Chemistry553,5270.39%2004-04-29
Dr.Professor Marvin H. Caruthers,PhDDirector177,7630.13%2011-06-30
Mr. R. Michael CarruthersN/A112,265less than 0.1%2013-07-24
Ron SquarerCEO108,166less than 0.1%2015-04-01
Dr. Victor Sandor, M.D.N/A42,768less than 0.1%2015-04-01
Mr. John R. MooreVP, General Counsel42,259less than 0.1%2015-04-01
Andrews R. RobbinsSVP, Commercial Operations39,375less than 0.1%2015-03-02
Dr. Nicholas A. SaccomanoN/A35,800less than 0.1%2015-04-01

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Redmile Group, LLC10% Owner2015-08-26Buy49,90017,250,510$5.48273.52.55
17,250,510 (See footnote)
Redmile Group, LLC10% Owner2015-08-25Buy790,00017,200,610$5.384250.24.46
17,200,610 (See Footnote)
Redmile Group, LLC10% Owner2015-08-12Buy532,50032,616,220$5.883131.1-4.42
16,205,610 (See footnote)
16,410,610 (See Footnote)
Redmile Group, LLC10% Owner2015-08-10Buy1,048,99315,878,110$5.86084.2-3.1
15,878,110 (See footnote)
BAUM CHARLES MDirector2015-05-08Sell25,0000$7.38184.5-23.85Link
LEFKOFF KYLEDirector2015-03-03Sell70,00048,585$8560-29.753,585 (Direct)
45,000 (See footnote)
Robbins Andrews RSVP, Commercial Operations2015-03-02Sell21,5760$8.25178-31.88Link
Squarer RonCEO
(Click for the stocks that their CEOs have bought)
2015-03-02Sell40,00012,927$8.25330-31.8812,927 (Direct)
MOORE JOHN RVP, General Counsel2013-11-29Sell11,66620$5.7967.5-2.9420 (Direct)
MOORE JOHN RVP, General Counsel2013-11-13Sell20011,686$5.791.2-2.9411,686 (Direct)
Ratcliffe LiamDirector2013-09-27Sell1,125,7280$66754.4-6.33
0 (See footnote)
Ratcliffe LiamDirector2013-09-16Sell1,673,1721,125,728$6.0810172.9-7.57
1,125,728 (See footnote)
Ratcliffe LiamDirector2013-09-06Sell577,2862,798,900$5.793342.5-2.94
2,798,900 (See footnote)
MOORE JOHN RVP, General Counsel2013-08-02Sell75,38411,886$7.02529.2-19.9411,886 (Direct)
MOORE JOHN RVP, General Counsel2013-07-23Sell5,00016,645$6.532.5-13.5416,645 (Direct)
MOORE JOHN RVP, General Counsel2012-10-08Sell28,54711,886$5.69162.4-1.2311,886 (Direct)
0 (Held by spouse)
CARRUTHERS MICHAELCFO2012-02-10Sell1,54594,570$2.654.1112.0894,570 (Direct)
CARRUTHERS MICHAELCFO2012-01-12Sell1,99496,115$2.064.1172.8296,115 (Direct)
CARRUTHERS MICHAELCFO2011-12-12Sell1,74396,295$2.354.1139.1596,295 (Direct)
BVF PARTNERS L P/IL10% Owner2011-12-05Buy183,8535,938,900$2.11387.9166.35
4,893,000 (See Explanation of Responses)
1,045,900 (See Explanation of Respones)

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

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