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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
John J. NicolsN/A901,3192.19%2016-06-13
Dr. Patrick Y. Yang, PhDN/A320,3400.78%2016-11-15
Mr. Douglas T. SheehyN/A247,6170.6%2016-03-05
Bernard KelleyDirector222,2630.54%2016-08-24
James LalondeN/A191,4730.46%2016-03-05
Thomas R. BaruchN/A179,2760.43%2016-06-15
Mr. Byron L. DorganN/A176,7760.43%2016-06-15
Gordon SangsterN/A126,2310.31%2016-08-18
Mr. Dennis P. WolfDirector123,3600.3%2016-08-26
Mr. David D. O'TooleN/A110,6870.27%2013-09-04

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Yang Patrick YDirector2016-11-15Buy10,000320,340$4.8348.3-3.73320,340 (Direct)
Vivo Ventures Fund VII, L.P.10% Owner2016-09-08Sell111,6005,294,825$4.25474.39.41
5,181,885 (By Vivo Ventures Fund VII, L.P.)
112,940 (By Vivo Ventures VII Affiliates Fund, L.P.)
WOLF DENNIS PDirector2016-08-29Sell18,000123,360$4.2275.9610.19123,360 (Direct)
KELLEY BERNARD JDirector2016-08-24Sell12,643222,263$4.2653.869.15222,263 (Direct)
Vivo Ventures Fund VII, L.P.10% Owner2016-08-16Sell86,8945,406,425$4.25369.39.41
5,291,104 (By Vivo Ventures Fund VI, L.P.)
115,321 (By Vivo Ventures VII Affiliates Fund, L.P.)
Vivo Ventures Fund VII, L.P.10% Owner2016-08-04Sell80,0005,493,319$4.22337.610.19
5,376,145 (By Vivo Ventures Fund VI, L.P.)
117,174 (By Vivo Ventures VII Affiliates Fund, L.P.)
Lalonde JamesSVP, R&D2015-11-11Sell9,441168,011$3.5233.2332.1168,011 (Direct)
Yang Patrick YDirector2015-09-11Buy10,000290,246$3.4734.734.01290,246 (Direct)
KELLEY BERNARD JDirector2015-09-10Sell5,200193,146$3.4517.9434.78193,146 (Direct)
Yang Patrick YDirector2015-08-24Buy10,000280,246$3.8438.421.09280,246 (Direct)
Yang Patrick YDirector2015-08-14Buy20,000270,246$3.9779.417.13270,246 (Direct)
WOLF DENNIS PDirector2015-06-15Sell35,416121,266$4.1145.2113.41121,266 (Direct)
Yang Patrick YDirector2014-11-18Buy20,000229,515$2.354797.87229,515 (Direct)
Yang Patrick YDirector2014-11-17Buy20,000209,515$2.3446.898.72209,515 (Direct)
CMEA VENTURES LIFE SCIENCES 20Director, 10% Owner2014-11-10Sell2,921,2250$2.376923.396.2
0 (See Footnote)
Yang Patrick YDirector2014-08-12Buy60,000189,515$2.22133.2109.46189,515 (Direct)
NICOLS JOHN JPresident & CEO
(Click for the stocks that their CEOs have bought)
2013-03-08Buy27,000911,000$2.4265.3492.15911,000 (Direct)
NICOLS JOHN JPresident & CEO2013-03-07Buy54,000884,000$2.22119.88109.46884,000 (Direct)
O'Toole David DSVP & CFO2013-03-04Buy10,000115,384$2.0220.2130.2115,384 (Direct)
O'Toole David DSVP & CFO2012-11-12Buy5,00060,000$2.211111.3660,000 (Direct)
Anton David L.SVP, BioIndustrials2012-09-14Sell3,80070,200$2.7610.4968.4870,200 (Direct)
Sheehy Douglas T.SVP, General Counsel & Sec.2012-09-14Sell3,80069,200$2.7610.4968.4869,200 (Direct)
O'Toole David DSVP & CFO2012-09-14Buy5,00055,000$2.7813.967.2755,000 (Direct)
SHAW ALANPresident and CEO2011-12-16Sell53,846277,000$5.28284.31-11.9375,000 (Direct)
202,000 (See Footnote)
SHAW ALANPresident and CEO2011-12-14Sell37,820330,846$5.27199.31-11.7675,000 (Direct)
255,846 (See Footnote)
SHAW ALANPresident and CEO2011-07-07Sell15,000368,666$10.13151.95-54.175,000 (Direct)
293,666 (See Footnote)
SHAW ALANPresident and CEO2011-06-02Sell15,000368,666$10.39155.85-55.2575,000 (Direct)
293,666 (See Footnote)
Lawson Robert JSVP and CFO2011-05-11Buy2,00044,000$9.519-51.0544,000 (Direct)
SHAW ALANPresident and CEO2011-05-02Sell15,0000$10.44156.6-55.46Link
SHAW ALANPresident and CEO2011-04-01Sell15,0000$12.07181.05-61.47Link
SHAW ALANPresident and CEO2011-03-01Sell15,0000$10.65159.75-56.34Link
SHAW ALANPresident and CEO2011-02-11Sell15,0000$10.46156.9-55.54Link
BARUCH THOMAS RDirector2010-08-27Buy2,5002,742,658$7.5518.88-38.41Link
Pasternack Bruce ADirector2010-08-24Buy10,00010,000$7.7877.8-40.23Link
SHAW ALANPresident and CEO2010-08-10Buy2,00096,132$816-41.88Link
Anton David L.SVP, Research and Development2010-08-10Buy2,0002,000$7.9915.98-41.8Link
Lawson Robert JSVP and CFO2010-08-10Buy2,0002,000$816-41.88Link
Sarret Joseph J.CBO, President Pharmaceuticals2010-08-10Buy2,00015,333$7.9915.98-41.8Link
Sheehy Douglas T.SVP, Gen Counsel and Sec.2010-08-10Buy1,0001,000$7.997.99-41.8Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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