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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Gregory I. Frost,PhDN/A3,641,3802.81%2013-12-11
Randal J. KirkN/A3,538,2532.73%2016-05-31
Dr. Jonathan E. Lim,M.D.N/A710,0000.55%2010-01-12
David A. RamsayN/A364,3200.28%2015-02-04
Kathryn E. FalbergN/A358,2530.28%2016-05-04
Dr. Robert L. Engler,M.D.N/A273,1760.21%2014-08-14
Connie L. MatsuiN/A223,2530.17%2016-05-04
Kenneth J. KelleyN/A188,2530.15%2016-05-04
Dr. John S. Patton,PhDN/A179,8760.14%2014-08-19
Dr. Helen Torley, MB.Ch.B.N/A127,4220.1%2016-06-30

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Stelzer LaurieCFO
(Click for the stocks that their CFOs have bought)
2015-08-20Buy10,00010,000$17.24172.4-45.36
10,000 (By trust)
Stelzer LaurieCFO
(Click for the stocks that their CFOs have bought)
2015-08-20Buy10,00010,000$17.24172.4-45.36
10,000 (By trust)
Kelley Kenneth JDirector2015-06-18Sell20,000198,051$21420-55.14198,051 (Direct)
Kelley Kenneth JDirector2015-03-05Sell40,000194,876$15.33613.2-38.55194,876 (Direct)
RAMSAY DAVID AVP and CFO
(Click for the stocks that their CFOs have bought)
2014-09-16Buy25,000323,492$8.9222.55.84323,492 (Direct)
Torley HelenPresident and CEO
(Click for the stocks that their CEOs have bought)
2014-09-16Buy50,00050,000$8.924465.6150,000 (Direct)
PATTON JOHN STUARTDirector2014-08-19Sell75,000179,876$9.96747-5.42179,876 (Direct)
Engler RobertDirector2014-08-14Sell35,000273,176$9.96348.6-5.42273,176 (Direct)
Engler RobertDirector2014-05-15Sell126,700233,176$7.56957.8524.6233,176 (Direct)
PATTON JOHN STUARTDirector2013-09-16Sell75,000155,000$9.13684.753.18155,000 (Direct)
Shepard H. MichaelVP, Chief Scientific Officer2013-08-19Sell10,00013,198$7.1171.132.4913,198 (Direct)
FALBERG KATHRYN EDirector2013-08-14Buy100,000280,000$6.8268238.12280,000 (Direct)
Engler RobertDirector2012-11-29Buy15,000165,000$5.5783.5569.12165,000 (Direct)
Shaffer James PVP & Chief Commercial Officer2012-11-14Buy20,00026,300$5.22104.480.4626,300 (Direct)
FALBERG KATHRYN EDirector2012-11-13Buy50,000160,000$5.21260.580.81160,000 (Direct)
Kelley Kenneth JDirector2012-08-27Buy20,000150,000$5.711465.26150,000 (Direct)
Frost Gregory IanCEO, President2012-08-13Buy2,0003,555,331$5.51171.273,555,331 (Direct)
KIRK RANDAL JDirector, 10% Owner2012-06-05Buy194,18919,929,503$7.381433.1127.643,450,000 (Direct)
331,395 (by JPK 2009)
331,394 (by MGK 2009)
3,977,445 (by Kapital Joe)
1,722,965 (by R.J. Kirk DOT)
293,000 (by JPK 2008)
293,000 (by MGK 2008)
293,000 (by ZSK 2008)
10,945 (by Lotus Capital)
1,436,186 (by Kirkfield)
135,000 (by Staff 2001)
1,326,320 (by NRM IV)
6,328,853 (by NRM V)
KIRK RANDAL JDirector, 10% Owner2012-05-17Buy1,071,49819,735,314$7.427950.5226.953,450,000 (Direct)
3,977,445 (by Kapital Joe)
234,300 (by JPK 2009)
234,300 (by MGK 2009)
1,722,965 (by R.J. Kirk DOT)
293,000 (by JPK 2008)
293,000 (by MGK 2008)
293,000 (by ZSK 2008)
10,945 (by Lotus Capital)
1,436,186 (by Kirkfield)
135,000 (by Staff 2001)
1,326,320 (by NRM IV)
6,328,853 (by NRM V)
Kelley Kenneth JDirector2012-05-14Buy20,000130,000$7.49149.825.77130,000 (Direct)
KIRK RANDAL JDirector, 10% Owner2012-02-10Buy1,360,00018,643,816$10.6114429.6-11.223,430,000 (Direct)
2,905,947 (by Kapital Joe)
234,300 (by JPK 2009)
234,300 (by MGK 2009)
1,722,965 (by R.J. Kirk DOT)
293,000 (by JPK 2008)
293,000 (by MGK 2008)
293,000 (by ZSK 2008)
10,945 (by Lotus Capital)
1,436,186 (by Kirkfield)
135,000 (by Staff 2001)
1,326,320 (by NRM IV)
6,328,853 (by NRM V)
KIRK RANDAL JDirector, 10% Owner2011-11-23Buy277,72317,283,816$8.032230.1217.313,430,000 (Direct)
1,915,947 (by Kapital Joe)
1,722,965 (by R.J. Kirk DOT)
49,300 (by JPK 2009)
49,300 (by MGK 2009)
293,000 (by JPK 2008)
293,000 (by MGK 2008)
293,000 (by ZSK 2008)
10,945 (by Lotus Capital)
1,436,186 (by Kirkfield)
135,000 (by Staff 2001)
1,326,320 (by NRM IV)
6,328,853 (by NRM V)
KIRK RANDAL JDirector, 10% Owner2011-11-16Buy638,22417,006,093$8.175214.2915.33,430,000 (Direct)
1,638,224 (by Kapital Joe)
1,722,965 (by R.J. Kirk DOT)
49,300 (by JPK 2009)
49,300 (by MGK 2009)
293,000 (by JPK 2008)
293,000 (by MGK 2008)
293,000 (by ZSK 2008)
10,945 (by Lotus Capital)
1,436,186 (by Kirkfield)
135,000 (by Staff 2001)
1,326,320 (by NRM IV)
6,328,853 (by NRM V)
Engler RobertDirector2011-11-14Buy5,000130,000$8.1540.7515.58130,000 (Direct)
KIRK RANDAL JDirector, 10% Owner2011-08-10Buy1,000,00016,367,869$5.95595058.323,430,000 (Direct)
1,000,000 (by Kapital Joe)
1,722,965 (by R.J. Kirk DOT)
49,300 (by JPK 2009)
49,300 (by MGK 2009)
293,000 (by JPK 2008)
293,000 (by MGK 2008)
293,000 (by ZSK 2008)
10,945 (by Lotus Capital)
1,436,186 (by Kirkfield)
135,000 (by Staff 2001)
1,326,320 (by NRM IV)
6,328,853 (by NRM V)
GUSTAFSON KURT AVice President and CFO2011-08-09Buy8,0008,000$5.8847.0460.28,000 (Direct)
Frost Gregory IanCEO, President2011-08-09Buy6,0003,536,866$5.8435.0461.33,536,866 (Direct)
Engler RobertDirector2008-12-16Buy10,00065,000$4.3843.8115.07
KIRK RANDAL JDirector, 10% Owner2008-06-23Buy28,4631,299,886$5.55157.9769.73
KIRK RANDAL JDirector, 10% Owner2008-06-23Buy713,2321,271,423$5.824151.0161.86
KIRK RANDAL JDirector, 10% Owner2008-06-20Buy235,400558,191$5.891386.5159.93
KIRK RANDAL JDirector, 10% Owner2008-06-18Buy104,627322,791$5.84611.0261.3
KIRK RANDAL JDirector, 10% Owner2008-06-13Buy218,164218,164$5.361169.3675.75
Frost Gregory IanVP and Chief Scientific Off., Director2008-03-20Sell230,0003,530,866$6.061393.855.45
Lim Jonathan EPresident, CEO, Director2008-03-20Sell250,000680,000$6.06151555.45
KIRK RANDAL JDirector, 10% Owner2008-03-20Buy1,264,6576,328,853$6.097701.7654.68
LITTLE ROBERT JVP, Chief Commercial Officer2008-03-20Buy9,00013,000$5.9753.7357.79
KIRK RANDAL JDirector, 10% Owner2008-03-19Buy1,094,1965,064,196$5.576094.6769.12
KIRK RANDAL JDirector, 10% Owner2008-03-19Buy1,094,1965,064,196$5.576094.6769.12
RAMSAY DAVID ASecretary, CFO2008-03-18Buy4,400411,410$4.620.24104.78
Frost Gregory IanVP and Chief Scientific Off., Director2007-12-20Sell9,1373,149,606$763.9634.57
Lim Jonathan EPresident, CEO, Director2007-11-30Sell20,000700,000$8.24164.814.32
Frost Gregory IanVP and Chief Scientific Off., Director2007-11-21Sell10,0003,109,606$7.6276.223.62
Frost Gregory IanVP and Chief Scientific Off., Director2007-11-20Sell1,9003,109,606$8.0415.2817.16
Frost Gregory IanVP and Chief Scientific Off., Director2007-11-20Sell9,8003,111,506$7.8476.8320.15
Lim Jonathan EPresident, CEO, Director2007-10-31Sell25,000700,000$9.03225.754.32
Frost Gregory IanVP and Chief Scientific Off., Director2007-10-25Sell15,0003,069,606$9.03135.454.32
Frost Gregory IanVP and Chief Scientific Off., Director2007-10-24Sell15,0003,069,606$8.98134.74.9
PATTON JOHN STUARTDirector2007-10-16Sell15,00015,000$9.04135.64.2
PATTON JOHN STUARTDirector2007-10-09Sell15,00030,000$8.69130.358.4
PATTON JOHN STUARTDirector2007-10-02Sell15,00045,000$8.9133.55.84
Lim Jonathan EPresident, CEO, Director2007-09-28Sell25,000673,310$8.78219.57.29
Frost Gregory IanVP and Chief Scientific Off., Director2007-09-27Sell15,0003,019,606$8.9133.55.84
Frost Gregory IanVP and Chief Scientific Off., Director2007-09-26Sell15,0003,019,606$9.06135.93.97
PATTON JOHN STUARTDirector2007-09-25Sell15,00060,000$8.94134.15.37
KIRK RANDAL JDirector, 10% Owner2007-09-19Buy38,5743,970,000$8.95345.245.25
PATTON JOHN STUARTDirector2007-09-18Sell17,47175,000$8.93156.025.49
KIRK RANDAL JDirector, 10% Owner2007-09-17Buy431,4263,931,426$8.693749.098.4
Lim Jonathan EPresident, CEO, Director2007-08-31Sell12,800673,310$8.82112.96.8
Lim Jonathan EPresident, CEO, Director2007-08-31Sell12,200686,110$8.57104.559.92
Frost Gregory IanVP and Chief Scientific Off., Director2007-08-30Sell15,0003,019,606$8.45126.7511.48
Frost Gregory IanVP and Chief Scientific Off., Director2007-08-29Sell15,0003,019,606$8.28124.213.77
Frost Gregory IanVP and Chief Scientific Off., Director2007-08-02Sell12,6012,969,606$8.01100.9317.6
Frost Gregory IanVP and Chief Scientific Off., Director2007-08-02Sell18,7002,980,906$8.03150.1617.31
Frost Gregory IanVP and Chief Scientific Off., Director2007-08-02Sell18,7002,980,906$8.03150.1617.31
Lim Jonathan EPresident, CEO, Director2007-07-31Sell20,000673,310$8.216414.88
RAMSAY DAVID ASecretary, CFO2007-07-16Sell10,000371,410$9.8998.9-4.75
PATTON JOHN STUARTDirector2007-07-10Sell20,00092,471$9.78195.6-3.68
Frost Gregory IanVP & Chief Scientific Ofcr, Director2007-07-06Sell25,0002,929,606$9.82245.5-4.07
Frost Gregory IanVP & Chief Scientific Ofcr, Director2007-07-05Sell15,0002,929,606$9.62144.3-2.08
Lim Jonathan EPresident, CEO, Director2007-06-29Sell8,199673,310$9.5978.63-1.77
Lim Jonathan EPresident, CEO, Director2007-06-29Sell16,801681,509$9.43158.43-0.11
PATTON JOHN STUARTDirector2007-06-26Sell8,200112,471$8.9873.644.9
PATTON JOHN STUARTDirector2007-06-26Sell11,800120,671$8.66102.198.78
PATTON JOHN STUARTDirector2007-06-19Sell20,000132,471$10.25205-8.1
Thornton Steven TDirector2007-06-15Sell10,00015,000$10.02100.2-5.99
RAMSAY DAVID ASecretary, CFO2007-06-14Sell10,000381,410$10.1101-6.73
PATTON JOHN STUARTDirector2007-06-12Sell20,000152,471$10.05201-6.27
Frost Gregory IanVP and Chief Scientific Off., Director2007-06-07Sell20,0002,887,365$10.47209.4-10.03
Frost Gregory IanVP and Chief Scientific Off., Director2007-06-07Sell20,0002,077,365$10.47209.4-10.03
Frost Gregory IanVP and Chief Scientific Off., Director2007-06-06Sell20,0002,887,365$10.57211.4-10.88
Frost Gregory IanVP and Chief Scientific Off., Director2007-06-06Sell20,0002,077,365$10.57211.4-10.88
Lim Jonathan EPresident, CEO, Director2007-05-31Sell5,900576,997$10.5962.48-11.05
Lim Jonathan EPresident, CEO, Director2007-05-31Sell19,100582,897$10.35197.69-8.99
KIRK RANDAL JDirector, 10% Owner2007-05-30Buy3,500,0003,500,000$9.17320952.73
PATTON JOHN STUARTDirector2007-05-29Sell20,000172,471$10.27205.4-8.28
Kelley Kenneth JDirector2007-05-25Sell22,50015,000$10.26230.85-8.19
PATTON JOHN STUARTDirector2007-05-23Sell15,000192,471$10.5157.5-10.29
PATTON JOHN STUARTDirector2007-05-22Sell20,000207,471$10.56211.2-10.8
Thornton Steven TDirector2007-05-21Sell30,00015,000$10.49314.7-10.2
Kelley Kenneth JDirector2007-05-18Sell15,00015,000$10.55158.25-10.71
Kelley Kenneth JDirector2007-05-07Sell12,50015,000$10.4130-9.42
Kelley Kenneth JDirector2007-04-30Sell25,00015,000$10.32258-8.72
Kelley Kenneth JDirector2007-04-23Sell25,00015,000$8.842216.56
PATTON JOHN STUARTDirector2007-04-18Sell25,000212,471$9.13228.253.18
Kelley Kenneth JDirector2007-04-16Sell25,00015,000$9.07226.753.86
PATTON JOHN STUARTDirector2007-04-11Sell25,000237,471$8.62215.59.28
Kelley Kenneth JDirector2007-04-09Sell25,00015,000$8.46211.511.35
PATTON JOHN STUARTDirector2007-04-04Sell25,000262,471$8.3620912.68
Kelley Kenneth JDirector2007-04-02Sell25,00015,000$8.05201.2517.02
PATTON JOHN STUARTDirector2007-03-28Sell25,000287,471$8.421012.14
PATTON JOHN STUARTDirector2007-03-28Sell25,0006,247$8.421012.14
Kelley Kenneth JDirector2007-03-27Sell50015,000$8.384.1912.41
Kelley Kenneth JDirector2007-03-27Sell24,50015,500$8.37205.0712.54
Thornton Steven TDirector2007-03-22Sell10,00030,000$8.4984.910.95
Yocum Richard CVP Clinical Development2007-03-22Sell29,85865,975$8.49253.4910.95
PATTON JOHN STUARTDirector2007-03-21Sell25,000312,471$8.59214.759.66
Kelley Kenneth JDirector2007-03-19Sell25,00015,000$8.7217.58.28
LITTLE ROBERT JVP, Chief Commercial Officer2007-03-19Buy4,0004,000$8.6534.68.9
LITTLE ROBERT JVP, Chief Commercial Officer2007-03-19Buy3,2003,200$8.6527.688.9
PATTON JOHN STUARTDirector2007-03-15Sell25,000337,471$8.01200.2517.6
Engler RobertDirector2007-03-15Sell25,00025,000$8.05201.2517.02
Kelley Kenneth JDirector2007-03-14Sell25,00015,000$7.9619918.34
KIRK RANDAL J10% Owner2007-03-14Buy76,280522,460$7.92604.1418.94
KIRK RANDAL J10% Owner2006-12-11Buy416,2001,262,000$5.672359.8566.14

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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