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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Donald J. SantelN/A348,5351.66%2015-05-01
Mr. Jeffrey S. FarrowN/A144,4020.69%2015-05-01
Dr. Bruce F. Scharschmidt, M.D.SVP & Chief Medical Officer104,4580.5%2015-05-01
Ms. Christine A. NashSVP & Chief Commercial Officer96,0900.46%2015-05-01
Ashley C. GouldN/A22,5760.11%2015-02-09
Natalie C. HollesN/A18,452less than 0.1%2015-02-09
Dr. James I. HealyDirector14,472less than 0.1%2014-06-04
Dr. Gaurav Aggarwal, M.D.Director5,000less than 0.1%2012-07-31
Theodore R. SchroederN/A3,700less than 0.1%2014-08-13
Mr. Jake R. NunnN/A2,617less than 0.1%2014-06-05

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Nash Christine ASVP & Chief Commercial Officer2015-03-17Sell10,00019,003$37.56375.622.4419,003 (Direct)
Nash Christine ASVP & Chief Commercial Officer2015-03-10Sell9,90019,003$29.63293.355.2119,003 (Direct)
Nash Christine ASVP & Chief Commercial Officer2015-03-10Sell10,00019,003$35.08350.831.119,003 (Direct)
Scharschmidt Bruce FrederickSVP & Chief Medical Officer2015-02-27Sell29,800151,171$29.89890.753.8697,471 (Direct)
29,252 (By The Bruce Frederick Scharschimdt and Peggy Sue)
24,448 (Crawford Family Trust dated October 9, 2001)
Nash Christine ASVP & Chief Commercial Officer2015-01-20Sell5,00028,903$24.82124.185.2928,903 (Direct)
Scharschmidt Bruce FrederickSVP & Chief Medical Officer2014-07-02Sell200132,197$285.664.2594,631 (Direct)
37,566 (By The Bruce Frederick Scharschmidt and Peggy Sue Crawford Family Trust dated October 9, 2001)
KOLLURI KRISHNA KITTU10% Owner2014-06-06Sell1202,384,221$27.193.369.14
2,384,221 (See Note 2)
0 (See Note 4)
0 (See Note 7)
0 (See Note 9)
0 (See Note 11)
BARRIS PETER J10% Owner2014-06-06Sell1,1342,384,511$26.930.570.97
0 (See Note 2)
2,384,221 (See Note 3)
222 (See Note 4)
68 (See Note 5)
BASKETT FOREST10% Owner2014-06-06Sell1,3772,384,221$26.93770.97
0 (See Note 2)
0 (See Note 4)
2,384,221 (See Note 5)
BARRETT M JAMES10% Owner2014-06-06Sell1,4302,384,221$26.8838.471.09
0 (See Note 3)
0 (See Note 5)
2,384,221 (See Note 6)
DRANT RYAN D10% Owner2014-06-06Sell1,1342,384,517$26.930.570.97266 (Direct)
0 (See Note 2)
2,384,221 (See Note 3)
30 (See Note 4)
SANDELL SCOTT D10% Owner2014-06-06Sell1,4302,384,221$5.547.9730.14
0 (See Note 2)
0 (See Note 4)
2,384,221 (See Note 5)
HEALY JAMESDirector2014-06-04Sell417,7471,953,946$27.711571.666.0314,472 (Direct)
1,939,474 (See footnote)
SOFINNOVA VENTURE PARTNERS VII10% Owner2014-06-04Sell417,7471,939,474$27.711571.666.031,939,474 (Direct)
Nash Christine ASVP & Chief Commercial Officer2014-03-06Sell5,10014,998$29.05148.258.3114,998 (Direct)
HEALY JAMESDirector, 10% Owner2014-03-04Sell23,62511,855$30.02709.253.211,855 (Direct)
0 (See footnote)
Nash Christine ASVP & Chief Commercial Officer2014-01-14Sell10,0005,098$24.09240.990.915,098 (Direct)
Highland Management Partners V10% Owner2013-09-20Sell5,7544,014,414$25.84148.777.98
1,235,364 (See Footnotes(F1,F5))
299,348 (See Footnotes(F2,F5))
435,946 (See Footnotes(F3,F5))
38,699 (See Footnotes(F4,F5))
1,232,721 (See Footnotes(F1,F6))
298,707 (See Footnotes(F2,F6))
435,013 (See Footnotes(F3,F6))
38,616 (See Footnotes(F4,F6))
Highland Management Partners V10% Owner2013-09-18Sell15,5444,027,392$26404.176.88
1,239,805 (See Footnotes(F1,F5))
300,425 (See Footnotes(F2,F5))
437,513 (See Footnotes(F3,F5))
38,838 (See Footnotes(F4,F5))
1,236,258 (See Footnotes(F1,F6))
299,565 (See Footnotes(F2,F6))
436,261 (See Footnotes(F3,F6))
38,727 (See Footnotes(F4,F6))
Highland Management Partners V10% Owner2013-09-16Sell8,3004,058,910$26.29218.274.93
1,249,626 (See Footnotes(F1,F5))
302,805 (See Footnotes(F2,F5))
440,979 (See Footnotes(F3,F5))
39,145 (See Footnotes(F4,F5))
1,245,814 (See Footnotes(F1,F6))
301,881 (See Footnotes(F2,F6))
439,634 (See Footnotes(F3,F6))
39,026 (See Footnotes(F4,F6))

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

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