Insider Buys and Sells of Isis Pharmaceuticals (ISIS)

20.39 (1y: +112%)

Market Cap	2.16 B	P/E(ttm)
Enterprise Value	1.97 B	P/B	11.40

ISIS- NAS (USA)
Isis Pharmaceuticals

Currently 1/5

Business Predictability Rank: 1-Star
Back Testing Results:
Average gain of all 1-Star stocks: 1.1% per year.
% of Stocks that are in still loss if held for 10yrs: 45%.
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$20.39

2 Severe Warning Signs 3 Medium Warning Signs 1 Good Sign

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Total Records: 140 Page:1 2 3 4 5 6 7

Insider	Position	Date	Buy/Sell	Shares	Shares Owned Following This	Trade Price ($)	Cost ($1000)	Price Change Since Trade (%)	Details
BENNETT C FRANK	SVP, Antisense Research	2013-05-01	Sell	59,945	2,110	$22.38	1341.6	-8.89	Link
CROOKE STANLEY T	Chairman, CEO and President (Click for the stocks that their CEOs have bought)	2013-04-24	Sell	10,000	827,226	$22.12	221.2	-7.82	Link
HOUGEN ELIZABETH L	SVP, Finance & CFO	2013-04-24	Sell	10,417	300	$22.38	233.1	-8.89	Link
PARSHALL B LYNNE	COO, Secretary	2013-04-25	Sell	55,854	2,941	$22.29	1245	-8.52	Link
Geary Richard S	SVP, Development	2013-04-19	Sell	2,042	4,254	$20.8	42.5	-1.97	Link
HOUGEN ELIZABETH L	SVP, Finance & CFO	2013-04-22	Sell	17,656	300	$21.46	378.9	-4.99	Link
CROOKE STANLEY T	Chairman, CEO and President	2013-04-23	Sell	90,000	837,226	$21.03	1892.7	-3.04	Link
Monia Brett P	SVP, Antisense Drug Discovery	2013-04-22	Sell	19,500	5,695	$21.26	414.6	-4.09	Link
PARSHALL B LYNNE	COO, Secretary	2013-04-23	Sell	90,000	2,941	$21.03	1892.7	-3.04	Link
O'NEIL PATRICK R.	SVP, Legal & General Counsel	2013-04-23	Sell	42,320	1,324	$21.5	909.9	-5.16	Link
Geary Richard S	Sr VP, Development	2013-04-11	Sell	7,000	4,254	$19.52	136.6	4.46	Link
O'NEIL PATRICK R.	SVP, Legal and General Counsel	2013-04-12	Sell	5,460	1,324	$19.61	107.1	3.98	Link
O'NEIL PATRICK R.	SVP, Legal and General Counsel	2013-03-21	Sell	9,000	1,324	$19.26	173.3	5.87	Link
Geary Richard S	Sr VP, Development	2013-03-21	Sell	1,000	4,254	$19.5	19.5	4.56	Link
KLEIN JOSEPH III	Director	2013-03-20	Sell	42,776	0	$18	770	13.28	Link
KLEIN JOSEPH III	Director	2013-03-20	Sell	3,924	8,000	$18	70.6	13.28	Link
HOUGEN ELIZABETH L	SVP, Finance and CFO	2013-03-20	Sell	14,376	300	$18.13	260.6	12.47	Link
KLEIN JOSEPH III	Director	2013-03-13	Sell	20,800	0	$18.01	374.6	13.21	Link
Monia Brett P	SVP, Antisense Drug Discovery	2013-03-05	Sell	18,240	5,695	$16.86	307.5	20.94	Link
HOUGEN ELIZABETH L	SVP, Finance and CFO	2013-03-05	Sell	5,040	300	$16.86	85	20.94	Link

Total Records: 140 Page:1 2 3 4 5 6 7

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

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