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Top Direct Holders

HolderPositionShares% of Shares
Report Date
Christopher F.O. GabrieliDirector155,4310.13%2004-05-14
Dr. Spencer R. Berthelsen,M.D.Director50,395less than 0.1%2014-07-01
Mr. Joseph H. WenderDirector37,217less than 0.1%2014-07-01
Dr. Stanley T. Crooke,M.D.,PhDChairman and CEO14,642less than 0.1%2015-01-27
Dr. Douglas L. Cole,PhDVice President9,616less than 0.1%2004-03-05
Ms. B. Lynne Parshall, J.D.COO & Secretary8,072less than 0.1%2015-01-15
Dr. Richard S. Geary,PhDSVP, Development7,570less than 0.1%2015-01-15
Holmlud Jon TN/A7,510less than 0.1%2004-01-01
Dr. C. Frank Bennett,PhDSVP, Antisense Research7,229less than 0.1%2015-01-15
Dr. Mark K. Wedel,M.D.,J.D.N/A6,603less than 0.1%2007-07-06

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
WENDER JOSEPH HDirector2015-03-02Sell7,00030,217$65.97461.88.78Link
WENDER JOSEPH HDirector2015-02-12Sell10,00037,217$62.15621.515.46Link
(Click for the stocks that their CEOs have bought)
CROOKE STANLEY TChairman and CEO2015-01-16Sell9,054725,391$67.96615.35.59Link
PARSHALL B LYNNECOO & Secretary2015-01-16Sell4,0938,072$67.96278.25.59Link
Monia Brett PSVP, Antisense Drug Discovery2015-01-16Sell1,5344,426$67.96104.35.59Link
HOUGEN ELIZABETH LSVP, Finance & CFO2015-01-16Sell1,2913,387$67.9687.75.59Link
O'NEIL PATRICK R.SVP, Legal & General Counsel2015-01-16Sell1,2916,174$67.9687.75.59Link
BENNETT C FRANKSVP, Antisense Research2015-01-16Sell1,5187,229$67.96103.25.59Link
Geary Richard SSVP, Development2015-01-16Sell1,5437,570$67.96104.95.59Link
Geary Richard SSVP, Development2015-01-12Sell5975,064$73.143.6-1.83Link
CROOKE STANLEY TChairman and CEO2015-01-09Sell11,000725,391$73.57809.3-2.46Link
CROOKE STANLEY TChairman and CEO2015-01-07Sell22,000725,391$67.041474.97.04Link
PARSHALL B LYNNECOO & Secretary2015-01-02Sell11,2004,417$62.12695.715.52Link
Monia Brett PSVP, Antisense Drug Discovery2015-01-02Sell761,935$62.754.814.36Link
O'NEIL PATRICK R.SVP, Legal & General Counsel2015-01-02Sell1,5004,082$62.1293.215.52Link
O'NEIL PATRICK R.SVP, Legal & General Counsel2014-12-01Sell1,5004,253$51.2176.840.13Link
ISIS PHARMACEUTICALS INC10% Owner2014-11-03Sell1,279,4115,516,305$15.9420393.8350.19Link
O'NEIL PATRICK R.SVP, Legal & General Counsel2014-11-03Sell1,5005,253$46.1769.355.43Link
PARSHALL B LYNNECOO & Secretary2014-10-30Sell11,07112,867$45.12499.559.04Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

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