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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Robert S. LangerN/A950,0221.38%2008-08-08
Alan L. CraneDirector613,8200.89%2010-04-14
Genesh Venkataraman Kaundinya, PhDSenior V.P., Research387,1050.56%2015-11-20
Dr. Ram Sasisekharan,PhDDirector340,2740.49%2010-07-23
Steven B. BruggerCOO264,9180.38%2010-10-28
Craig A. WheelerPresident200,8440.29%2015-11-20
Dr. John L. Zabriskie,PhDN/A149,5980.22%2004-06-25
Richard P. SheaSVP, CFO142,5110.21%2015-11-20
Bruce A. LeicherSVP & General Counsel116,0820.17%2015-11-20
John Bishop,PhDSenior VP, Pharmaceutical Scie93,5200.14%2015-11-20

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Franken MichaelPresident, Biosimilars Busines2015-12-11Sell52037,968$15.848.2-25.6937,968 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-11-23Sell54893,520$17.779.7-33.7693,520 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-11-20Sell227387,105$17.754-33.69387,105 (Direct)
Roach James M.Senior VP, Development and Chi2015-11-20Sell36090,441$17.756.4-33.6990,441 (Direct)
WHEELER CRAIG APresident2015-11-20Sell1,766528,158$17.8631.5-34.1200,844 (Direct)
177,314 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-11-20Sell227142,511$17.754-33.69142,511 (Direct)
Leicher BruceSVP & General Counsel2015-11-20Sell328116,082$17.755.8-33.69116,082 (Direct)
Leicher BruceSVP & General Counsel2015-11-19Sell603116,410$18.1711-35.22116,410 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-11-19Sell397387,332$18.177.2-35.22387,332 (Direct)
Roach James M.Senior VP, Development and Chi2015-11-19Sell60390,801$18.1711-35.2290,801 (Direct)
WHEELER CRAIG APresident2015-11-19Sell2,061529,924$18.0537.2-34.79202,610 (Direct)
177,314 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-11-19Sell397142,738$18.177.2-35.22142,738 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-11-19Sell65094,068$18.1211.8-35.0494,068 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-11-17Sell216387,729$17.653.8-33.31387,729 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-11-17Sell145143,135$17.652.6-33.31143,135 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-11-17Sell31294,718$17.655.5-33.3194,718 (Direct)
WHEELER CRAIG APresident2015-11-17Sell1,766531,985$17.731.3-33.5204,671 (Direct)
177,314 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Roach James M.Senior VP, Development and Chi2015-11-17Sell31291,404$17.655.5-33.3191,404 (Direct)
Leicher BruceSVP & General Counsel2015-11-17Sell387117,013$17.656.8-33.31117,013 (Direct)
WHEELER CRAIG APresident2015-11-05Sell51,667533,751$18930-34.61206,437 (Direct)
177,314 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Franken MichaelPresident, Biosimilars Busines2015-09-11Sell51338,488$18.929.7-37.7938,488 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-08-21Sell54995,030$21.8812-46.2195,030 (Direct)
Leicher BruceSVP & General Counsel2015-08-20Sell330117,400$22.27.3-46.98117,400 (Direct)
Roach James M.Senior VP, Development and Chi2015-08-20Sell36391,716$22.28.1-46.9891,716 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-08-20Sell228387,945$22.25.1-46.98387,945 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-08-20Sell228143,280$22.25.1-46.98143,280 (Direct)
WHEELER CRAIG APresident2015-08-20Sell1,766543,751$22.2839.3-47.17212,719 (Direct)
181,032 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Leicher BruceSVP & General Counsel2015-08-19Sell601117,730$2213.2-46.5117,730 (Direct)
WHEELER CRAIG APresident2015-08-19Sell2,061545,517$22.0245.4-46.55214,485 (Direct)
181,032 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-08-19Sell396143,508$228.7-46.5143,508 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-08-19Sell396388,173$228.7-46.5388,173 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-08-19Sell57395,579$2212.6-46.595,579 (Direct)
Roach James M.Senior VP, Development and Chi2015-08-19Sell7,01192,079$22.09154.9-46.7292,079 (Direct)
Roach James M.Senior VP, Development and Chi2015-08-18Sell6,81299,090$21.8148.5-46.0199,090 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-08-18Sell3,22896,152$21.7970.3-45.9896,152 (Direct)
WHEELER CRAIG APresident2015-08-17Sell1,766547,578$21.7738.4-45.93216,546 (Direct)
181,032 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-08-17Sell144143,904$21.673.1-45.69143,904 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-08-17Sell216388,569$21.674.7-45.69388,569 (Direct)
Leicher BruceSVP & General Counsel2015-08-17Sell386118,331$21.678.4-45.69118,331 (Direct)
Franken MichaelPresident, Biosimilars Busines2015-08-10Sell20,00039,001$22.36447.2-47.3639,001 (Direct)
Stoner ElizabethDirector2015-07-15Sell4,57013,240$22.35102.1-47.3413,240 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-06-19Sell21,27499,380$25.5542.5-53.8499,380 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-06-18Sell36,31399,380$23.58856.3-50.0899,380 (Direct)
Roach James M.Senior VP, Development and Chi2015-06-18Sell25,000105,902$23.7592.5-50.34105,902 (Direct)
Leicher BruceSVP & General Counsel2015-06-18Sell20,000117,817$23460-48.83117,817 (Direct)
WHEELER CRAIG APresident2015-06-18Sell155,000549,344$24.23751-51.36218,312 (Direct)
181,032 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Franken MichaelPresident, Biosimilars Busines2015-06-11Sell51239,001$22.3711.5-47.3839,001 (Direct)
WHEELER CRAIG APresident2015-06-04Sell103,333579,344$222273.3-46.5218,312 (Direct)
211,032 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Leicher BruceSVP & General Counsel2015-06-01Sell40,000117,817$21840-43.95117,817 (Direct)
Roach James M.Senior VP, Development and Chi2015-06-01Sell25,000105,902$21.7542.5-45.76105,902 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-05-26Sell254110,380$19.85-40.56110,380 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-05-20Sell227144,048$19.684.5-40.19144,048 (Direct)
Leicher BruceSVP & General Counsel2015-05-20Sell227117,817$19.684.5-40.19117,817 (Direct)
Roach James M.Senior VP, Development and Chi2015-05-20Sell360105,902$19.687.1-40.19105,902 (Direct)
WHEELER CRAIG APresident2015-05-20Sell1,766599,344$19.6834.8-40.19224,594 (Direct)
224,750 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Bishop John ESenior VP, Pharmaceutical Scie2015-05-20Sell227110,634$19.684.5-40.19110,634 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-05-20Sell227388,785$19.684.5-40.19388,785 (Direct)
Leicher BruceSVP & General Counsel2015-05-19Sell426118,044$19.638.4-40.04118,044 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-05-19Sell624110,861$19.6312.2-40.04110,861 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-05-19Sell406389,012$19.638-40.04389,012 (Direct)
Roach James M.Senior VP, Development and Chi2015-05-19Sell617106,262$19.6312.1-40.04106,262 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-05-19Sell406144,275$19.638-40.04144,275 (Direct)
WHEELER CRAIG APresident2015-05-19Sell2,061601,110$19.6740.5-40.16226,360 (Direct)
224,750 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Leicher BruceSVP & General Counsel2015-05-15Sell267118,470$19.965.3-41.03118,470 (Direct)
Roach James M.Senior VP, Development and Chi2015-05-15Sell311106,879$19.966.2-41.03106,879 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-05-15Sell145144,681$19.962.9-41.03144,681 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-05-15Sell215389,418$19.964.3-41.03389,418 (Direct)
WHEELER CRAIG APresident2015-05-15Sell1,766603,171$19.9235.2-40.91228,421 (Direct)
224,750 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
CLARKE JOHN KDirector2015-05-12Sell38,40069,123$19.96766.5-41.0369,123 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-05-11Sell33,625111,485$20.7696-43.14111,485 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-05-06Sell493111,485$19.059.4-38.22111,485 (Direct)
WHEELER CRAIG APresident2015-04-23Sell51,667604,937$201033.3-41.15258,629 (Direct)
196,308 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-04-23Sell34,000389,633$19.95678.3-41389,633 (Direct)
WHEELER CRAIG APresident2015-04-20Sell6,269614,937$18.75117.5-37.23258,629 (Direct)
206,308 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Leicher BruceSVP & General Counsel2015-04-17Sell52,910118,737$19.521032.8-39.7118,737 (Direct)
Roach James M.Senior VP, Development and Chi2015-04-16Sell50,000107,190$18.7935-37.06107,190 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-03-16Sell23,093157,791$15.1348.7-22.05157,791 (Direct)
Franken MichaelPresident, Biosimilars Busines2015-03-11Sell51239,513$14.717.5-19.9939,513 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-03-05Sell23,364180,884$14.9348.1-21.01180,884 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-02-25Sell64124,943$13.20.8-10.83124,943 (Direct)
WHEELER CRAIG APresident2015-02-24Sell2,110671,308$13.5228.5-12.94337,769 (Direct)
183,539 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Bishop John ESenior VP, Pharmaceutical Scie2015-02-24Sell340125,007$13.324.5-11.64125,007 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-02-24Sell192204,248$13.562.6-13.2204,248 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-02-24Sell211436,598$13.562.9-13.2436,598 (Direct)
Leicher BruceSVP & General Counsel2015-02-24Sell192144,612$13.562.6-13.2144,612 (Direct)
Roach James M.Senior VP, Development and Chi2015-02-24Sell391120,155$13.245.2-11.1120,155 (Direct)
Leicher BruceSVP & General Counsel2015-02-20Sell1,891144,804$12.9724.5-9.25144,804 (Direct)
Roach James M.Senior VP, Development and Chi2015-02-20Sell1,913120,546$12.9724.8-9.25120,546 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-02-20Sell1,768125,347$12.9722.9-9.25125,347 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-02-20Sell1,812436,809$12.9723.5-9.25436,809 (Direct)
WHEELER CRAIG APresident2015-02-20Sell9,563673,418$13.49129-12.75339,879 (Direct)
183,539 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-02-20Sell1,812204,440$12.9723.5-9.25204,440 (Direct)
Leicher BruceSVP & General Counsel2015-02-18Sell312146,695$11.913.7-1.18146,695 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2015-02-18Sell169206,252$11.912-1.18206,252 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2015-02-18Sell252127,115$11.913-1.18127,115 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2015-02-18Sell252438,621$11.913-1.18438,621 (Direct)
Roach James M.Senior VP, Development and Chi2015-02-18Sell252122,459$11.913-1.18122,459 (Direct)
WHEELER CRAIG APresident2015-02-18Sell1,688682,981$11.9120.1-1.18349,442 (Direct)
183,539 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Shapiro Bennett MDirector2014-12-15Sell5,80010,834$12.1970.7-3.4510,834 (Direct)
Franken MichaelPresident, Biosimilars Busines2014-12-11Sell2,04722,953$12.2925.2-4.2322,953 (Direct)
Shapiro Bennett MDirector2014-12-01Sell9,90310,834$12118.8-1.9210,834 (Direct)
Shapiro Bennett MDirector2014-11-28Sell1,89710,834$1222.8-1.9210,834 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-11-26Sell64108,505$11.60.71.47108,505 (Direct)
WHEELER CRAIG APresident2014-11-25Sell2,210614,669$11.5925.61.55281,130 (Direct)
183,539 (Craig Wheeler Revocable Trust)
150,000 (Craig A. Wheeler 2014 Irrevocable Trust)
Bishop John ESenior VP, Pharmaceutical Scie2014-11-25Sell346108,569$11.6241.29108,569 (Direct)
Roach James M.Senior VP, Development and Chi2014-11-25Sell391101,963$11.64.51.47101,963 (Direct)
Leicher BruceSVP & General Counsel2014-11-25Sell192126,998$11.672.20.86126,998 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-11-25Sell211393,125$11.672.50.86393,125 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-11-25Sell192177,751$11.672.20.86177,751 (Direct)
Leicher BruceSVP & General Counsel2014-11-20Sell228127,190$11.132.55.75127,190 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-11-20Sell228108,915$11.132.55.75108,915 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-11-20Sell228393,336$11.132.55.75393,336 (Direct)
Roach James M.Senior VP, Development and Chi2014-11-20Sell250102,354$11.132.85.75102,354 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-11-20Sell228177,943$11.132.55.75177,943 (Direct)
WHEELER CRAIG APresident2014-11-20Sell1,768616,879$11.119.66.04364,773 (Direct)
252,106 (Craig Wheeler revocable trust)
Roach James M.Senior VP, Development and Chi2014-11-17Sell217102,604$10.642.310.62102,604 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-11-17Sell217109,143$10.642.310.62109,143 (Direct)
Leicher BruceSVP & General Counsel2014-11-17Sell269127,418$10.642.910.62127,418 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-11-17Sell217393,564$10.642.310.62393,564 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-11-17Sell146178,171$10.641.610.62178,171 (Direct)
WHEELER CRAIG APresident2014-11-17Sell1,768618,647$10.5818.711.25366,541 (Direct)
252,106 (Craig Wheeler revocable trust)
Shapiro Bennett MDirector2014-10-03Sell3,72310,834$1244.7-1.9210,834 (Direct)
HUTT PETER BARTONDirector2014-09-12Sell3,6406,725$11.4241.63.066,725 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-08-27Sell64109,360$120.8-1.92109,360 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-08-25Sell346109,424$11.4542.79109,424 (Direct)
WHEELER CRAIG APresident2014-08-25Sell2,209620,415$11.4525.32.79368,309 (Direct)
252,106 (Craig Wheeler revocable trust)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-08-25Sell211393,781$11.452.42.79393,781 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-08-25Sell192178,317$11.452.22.79178,317 (Direct)
Roach James M.Senior VP, Development and Chi2014-08-25Sell391102,821$11.384.43.43102,821 (Direct)
Leicher BruceSVP & General Counsel2014-08-25Sell192127,687$11.452.22.79127,687 (Direct)
Leicher BruceSVP & General Counsel2014-08-20Sell228127,879$11.542.61.99127,879 (Direct)
WHEELER CRAIG APresident2014-08-20Sell1,768622,624$11.5420.41.99370,518 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2014-08-20Sell228109,770$11.542.61.99109,770 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-08-20Sell228393,992$11.542.61.99393,992 (Direct)
Roach James M.Senior VP, Development and Chi2014-08-20Sell250103,212$11.542.91.99103,212 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-08-20Sell228178,509$11.542.61.99178,509 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-08-18Sell145178,737$11.841.7-0.59178,737 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-08-15Sell217109,998$11.752.50.17109,998 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-08-15Sell217394,220$11.752.50.17394,220 (Direct)
Shapiro Bennett MDirector2014-08-15Sell3,7229,557$1244.7-1.929,557 (Direct)
Roach James M.Senior VP, Development and Chi2014-08-15Sell217103,462$11.752.50.17103,462 (Direct)
WHEELER CRAIG APresident2014-08-15Sell1,768624,392$11.7520.80.17372,286 (Direct)
252,106 (Craig Wheeler revocable trust)
Leicher BruceSVP & General Counsel2014-08-15Sell268128,107$11.753.10.17128,107 (Direct)
Shapiro Bennett MDirector2014-08-13Sell3,7218,279$1244.7-1.928,279 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-05-27Sell64110,215$12.240.8-3.84110,215 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-05-23Sell192178,882$12.092.3-2.65178,882 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-05-23Sell346110,279$12.094.2-2.65110,279 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-05-23Sell211394,437$12.092.6-2.65394,437 (Direct)
Roach James M.Senior VP, Development and Chi2014-05-23Sell391103,679$11.914.7-1.18103,679 (Direct)
Leicher BruceSVP & General Counsel2014-05-23Sell192127,582$12.092.3-2.65127,582 (Direct)
WHEELER CRAIG APresident2014-05-23Sell2,110626,160$12.0625.4-2.4374,054 (Direct)
252,106 (Craig Wheeler revocable trust)
Leicher BruceSVP & General Counsel2014-05-20Sell227127,774$12.082.7-2.57127,774 (Direct)
Roach James M.Senior VP, Development and Chi2014-05-20Sell250104,070$12.083-2.57104,070 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-05-20Sell227394,648$12.082.7-2.57394,648 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-05-20Sell227110,625$12.082.7-2.57110,625 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-05-20Sell227179,074$12.082.7-2.57179,074 (Direct)
WHEELER CRAIG APresident2014-05-20Sell1,688628,270$12.0820.4-2.57376,164 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2014-05-15Sell217110,852$11.092.46.13110,852 (Direct)
Leicher BruceSVP & General Counsel2014-05-15Sell269128,001$11.0936.13128,001 (Direct)
Roach James M.Senior VP, Development and Chi2014-05-15Sell217104,320$11.092.46.13104,320 (Direct)
WHEELER CRAIG APresident2014-05-15Sell1,687629,958$11.0918.76.13377,852 (Direct)
252,106 (Craig Wheeler revocable trust)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-05-15Sell217394,875$11.092.46.13394,875 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-05-15Sell146179,301$11.091.66.13179,301 (Direct)
Roach James M.Senior VP, Development and Chi2014-04-15Sell485104,537$10.765.29.39104,537 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-03-04Sell64111,069$14.410.9-18.32111,069 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-02-27Sell211111,133$17.493.7-32.7111,133 (Direct)
Leicher BruceSVP & General Counsel2014-02-25Sell192128,270$17.473.4-32.63128,270 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-02-25Sell211363,892$17.473.7-32.63363,892 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-02-25Sell192179,447$17.473.4-32.63179,447 (Direct)
Roach James M.Senior VP, Development and Chi2014-02-25Sell192105,022$17.473.4-32.63105,022 (Direct)
WHEELER CRAIG APresident2014-02-25Sell2,109631,645$17.4736.8-32.63379,539 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2014-02-25Sell277111,344$17.474.8-32.63111,344 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-02-24Sell1,038111,621$17.6718.3-33.39111,621 (Direct)
Leicher BruceSVP & General Counsel2014-02-21Sell904128,462$17.716-33.5128,462 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-02-21Sell904179,639$17.716-33.5179,639 (Direct)
Roach James M.Senior VP, Development and Chi2014-02-21Sell995105,214$17.717.6-33.5105,214 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-02-21Sell904364,103$17.716-33.5364,103 (Direct)
WHEELER CRAIG APresident2014-02-20Sell6,750633,754$17.68119.3-33.43381,648 (Direct)
252,106 (Craig Wheeler revocable trust)
Roach James M.Senior VP, Development and Chi2014-02-19Sell414106,209$17.917.4-34.28106,209 (Direct)
Leicher BruceSVP & General Counsel2014-02-19Sell465129,366$17.928.3-34.32129,366 (Direct)
WHEELER CRAIG APresident2014-02-19Sell3,797640,504$17.968-34.25388,398 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2014-02-19Sell433112,659$17.867.7-34.1112,659 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2014-02-19Sell342167,743$17.96.1-34.25167,743 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-02-19Sell434365,007$17.917.8-34.28365,007 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2014-02-12Sell33,000346,129$17.96592.7-34.47346,129 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2014-01-09Sell27,15993,780$19.5529.6-39.6493,780 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2013-11-26Sell6493,780$18.091.2-34.9493,780 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-11-25Sell33,211391,129$18.02598.5-34.68391,129 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2013-11-25Sell34393,844$17.776.1-33.7693,844 (Direct)
Roach James M.Senior VP, Development and Chi2013-11-25Sell19286,345$17.773.4-33.7686,345 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-11-25Sell277148,773$17.774.9-33.76148,773 (Direct)
WHEELER CRAIG APresident2013-11-25Sell2,215574,301$17.7739.4-33.76322,195 (Direct)
252,106 (Craig Wheeler revocable trust)
Leicher BruceSVP & General Counsel2013-11-25Sell13,492108,975$18242.9-34.61108,975 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2013-11-19Sell21794,187$17.173.7-31.4594,187 (Direct)
WHEELER CRAIG APresident2013-11-19Sell2,215576,516$17.1738-31.45324,410 (Direct)
252,106 (Craig Wheeler revocable trust)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-11-19Sell217424,340$17.173.7-31.45424,340 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-11-19Sell284149,050$17.174.9-31.45149,050 (Direct)
Roach James M.Senior VP, Development and Chi2013-11-19Sell19786,537$17.173.4-31.4586,537 (Direct)
Leicher BruceSVP & General Counsel2013-11-19Sell197109,167$17.173.4-31.45109,167 (Direct)
Leicher BruceSVP & General Counsel2013-11-18Sell266109,364$17.194.6-31.53109,364 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2013-11-18Sell21494,404$17.193.7-31.5394,404 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-11-15Sell210149,334$16.883.5-30.27149,334 (Direct)
Roach James M.Senior VP, Development and Chi2013-11-15Sell21786,734$16.883.7-30.2786,734 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-11-15Sell217424,557$16.883.7-30.27424,557 (Direct)
WHEELER CRAIG APresident2013-11-15Sell1,772578,731$16.8829.9-30.27326,625 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2013-10-11Sell5,24794,618$15.4681.1-23.8794,618 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2013-08-27Sell6499,865$151-21.5399,865 (Direct)
Leicher BruceSVP & General Counsel2013-08-27Sell190109,630$152.9-21.53109,630 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-08-23Sell277149,544$14.94.1-21.01149,544 (Direct)
WHEELER CRAIG APresident2013-08-23Sell2,109580,503$14.931.4-21.01328,397 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2013-08-23Sell34499,929$14.95.1-21.0199,929 (Direct)
Roach James M.Senior VP, Development and Chi2013-08-23Sell19286,951$14.92.9-21.0186,951 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-08-23Sell212424,774$14.93.2-21.01424,774 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-08-20Sell284149,821$14.474.1-18.66149,821 (Direct)
WHEELER CRAIG APresident2013-08-20Sell2,109582,612$14.4730.5-18.66330,506 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2013-08-20Sell217100,273$14.473.1-18.66100,273 (Direct)
Leicher BruceSVP & General Counsel2013-08-20Sell197109,820$14.472.9-18.66109,820 (Direct)
Roach James M.Senior VP, Development and Chi2013-08-20Sell19787,143$14.472.9-18.6687,143 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-08-20Sell217424,986$14.473.1-18.66424,986 (Direct)
Leicher BruceSVP & General Counsel2013-08-15Sell270110,017$15.434.2-23.72110,017 (Direct)
Roach James M.Senior VP, Development and Chi2013-08-15Sell21887,340$15.433.4-23.7287,340 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-08-15Sell218425,203$15.433.4-23.72425,203 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2013-08-15Sell218100,490$15.433.4-23.72100,490 (Direct)
WHEELER CRAIG APresident2013-08-15Sell1,688584,721$15.4326-23.72332,615 (Direct)
252,106 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-08-15Sell211150,105$15.433.3-23.72150,105 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-07-26Sell30,000150,316$16.61498.3-29.14150,316 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-06-27Sell10,522150,316$14.61153.7-19.44150,316 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-06-19Sell21,550150,316$14.61314.8-19.44150,316 (Direct)
Leicher BruceSVP & General Counsel2013-05-23Sell195109,588$13.032.5-9.67109,588 (Direct)
WHEELER CRAIG APresident2013-05-23Sell2,109586,409$13.0327.5-9.67334,303 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2013-05-23Sell246100,708$13.033.2-9.67100,708 (Direct)
Roach James M.Senior VP, Development and Chi2013-05-23Sell19587,558$13.032.5-9.6787,558 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-05-23Sell195150,316$13.032.5-9.67150,316 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-05-23Sell214425,421$13.032.8-9.67425,421 (Direct)
WHEELER CRAIG APresident2013-05-21Sell2,109588,518$12.8327.1-8.26336,412 (Direct)
252,106 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-05-21Sell197150,511$12.832.5-8.26150,511 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-05-21Sell217425,635$12.832.8-8.26425,635 (Direct)
Leicher BruceSVP & General Counsel2013-05-21Sell197109,783$12.832.5-8.26109,783 (Direct)
Roach James M.Senior VP, Development and Chi2013-05-21Sell19787,753$12.832.5-8.2687,753 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2013-05-21Sell250100,954$12.833.2-8.26100,954 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-05-16Sell146150,708$13.311.9-11.57150,708 (Direct)
Leicher BruceSVP & General Counsel2013-05-15Sell269109,980$13.333.6-11.7109,980 (Direct)
WHEELER CRAIG APresident2013-05-15Sell1,687590,627$13.3322.5-11.7338,521 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2013-05-15Sell250101,204$13.333.3-11.7101,204 (Direct)
Roach James M.Senior VP, Development and Chi2013-05-15Sell21787,950$13.332.9-11.787,950 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-05-15Sell217425,852$13.332.9-11.7425,852 (Direct)
Fanucci MarshaDirector2013-03-15Sell29,4009,000$14.15416-16.829,000 (Direct)
Stoner ElizabethDirector2013-03-05Sell2,04011,143$1428.6-15.9311,143 (Direct)
WHEELER CRAIG APresident2013-02-26Sell4,218592,314$12.5152.8-5.92340,208 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2013-02-26Sell473101,454$12.55.9-5.84101,454 (Direct)
Leicher BruceSVP & General Counsel2013-02-26Sell153110,249$12.581.9-6.44110,249 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-02-26Sell391426,069$12.54.9-5.84426,069 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-02-26Sell362150,854$12.54.5-5.84150,854 (Direct)
Roach James M.Senior VP, Development and Chi2013-02-26Sell38188,167$12.514.8-5.9288,167 (Direct)
Leicher BruceSVP & General Counsel2013-02-25Sell189110,402$12.432.3-5.31110,402 (Direct)
Leicher BruceSVP & General Counsel2013-02-20Sell188110,591$12.622.4-6.74110,591 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2013-02-20Sell239101,927$12.623-6.74101,927 (Direct)
Roach James M.Senior VP, Development and Chi2013-02-20Sell18888,548$12.622.4-6.7488,548 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2013-02-20Sell731151,216$12.629.2-6.74151,216 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-02-20Sell207426,460$12.622.6-6.74426,460 (Direct)
WHEELER CRAIG APresident2013-02-20Sell2,109596,532$12.6226.6-6.74344,426 (Direct)
252,106 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2013-02-15Sell97091,166$12.2611.9-491,166 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2013-02-15Sell838415,667$12.2610.3-4415,667 (Direct)
Roach James M.Senior VP, Development and Chi2013-02-15Sell83876,636$12.2610.3-476,636 (Direct)
WHEELER CRAIG APresident2013-02-15Sell6,750538,641$12.1682.1-3.21286,535 (Direct)
252,106 (Craig Wheeler revocable trust)
Leicher BruceSVP & General Counsel2013-02-15Sell1,04099,779$12.2612.8-499,779 (Direct)
Leicher BruceSVP & General Counsel2012-11-27Sell324100,144$10.563.411.46100,144 (Direct)
WHEELER CRAIG APresident2012-11-27Sell2,109545,391$10.5322.211.78293,285 (Direct)
252,106 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-11-27Sell362140,947$10.563.811.46140,947 (Direct)
Roach James M.Senior VP, Development and Chi2012-11-27Sell38077,474$10.55411.5677,474 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2012-11-27Sell389409,305$10.564.111.46409,305 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-11-27Sell47292,136$10.56511.4692,136 (Direct)
WHEELER CRAIG APresident2012-11-26Sell2,109547,500$10.5822.311.25295,394 (Direct)
252,106 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-11-21Sell197141,309$10.742.19.59141,309 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2012-11-20Sell211409,694$10.962.37.39409,694 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-11-20Sell24492,608$10.962.77.3992,608 (Direct)
WHEELER CRAIG APresident2012-11-20Sell2,109549,609$10.9623.17.39297,503 (Direct)
252,106 (Craig Wheeler revocable trust)
Roach James M.Senior VP, Development and Chi2012-11-20Sell19377,854$10.962.17.3977,854 (Direct)
Leicher BruceSVP & General Counsel2012-11-20Sell193100,468$10.962.17.39100,468 (Direct)
Stoner ElizabethDirector2012-10-01Sell1,0009,849$14.5314.5-199,849 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-08-29Sell2,39792,852$14.5734.9-19.2292,852 (Direct)
Leicher BruceSVP & General Counsel2012-08-28Sell135100,661$14.351.9-17.98100,661 (Direct)
WHEELER CRAIG APresident2012-08-28Sell2,109551,718$14.2130-17.17299,612 (Direct)
252,106 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-08-28Sell173141,506$14.352.5-17.98141,506 (Direct)
Roach James M.Senior VP, Development and Chi2012-08-28Sell19278,047$14.352.8-17.9878,047 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2012-08-28Sell182409,905$14.352.6-17.98409,905 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-08-28Sell23295,249$14.353.3-17.9895,249 (Direct)
Roach James M.Senior VP, Development and Chi2012-08-23Sell18778,239$13.642.6-13.7178,239 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2012-08-23Sell206410,087$13.642.8-13.71410,087 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-08-23Sell23895,481$13.643.2-13.7195,481 (Direct)
Leicher BruceSVP & General Counsel2012-08-23Sell187100,796$13.642.6-13.71100,796 (Direct)
WHEELER CRAIG APresident2012-08-23Sell2,109553,827$13.5728.6-13.26301,721 (Direct)
252,106 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-08-23Sell380141,679$13.645.2-13.71141,679 (Direct)
WHEELER CRAIG APresident2012-08-21Sell2,109555,936$13.6328.7-13.65303,830 (Direct)
252,106 (Craig Wheeler revocable trust)
Roach James M.Senior VP, Development and Chi2012-08-21Sell19378,426$13.782.7-14.5978,426 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2012-08-21Sell211410,293$13.782.9-14.59410,293 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-08-21Sell24495,719$13.783.4-14.5995,719 (Direct)
Leicher BruceSVP & General Counsel2012-08-21Sell696100,983$13.789.6-14.59100,983 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-08-10Sell7,48595,963$13.58101.6-13.3395,963 (Direct)
Stoner ElizabethDirector2012-08-01Sell1,0109,182$14.2114.4-17.179,182 (Direct)
Shapiro Bennett MDirector2012-07-10Sell1,6007,000$14.1222.6-16.647,000 (Direct)
Shapiro Bennett MDirector2012-06-11Sell4007,000$14.845.9-20.697,000 (Direct)
Stoner ElizabethDirector2012-06-04Sell1,0208,526$1414.3-15.938,526 (Direct)
Leicher BruceSVP & General Counsel2012-05-29Sell135101,081$13.931.9-15.51101,081 (Direct)
WHEELER CRAIG APresident2012-05-29Sell2,110558,045$13.7929.1-14.65331,719 (Direct)
226,326 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2012-05-29Sell233103,448$13.933.2-15.51103,448 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2012-05-29Sell182410,504$13.932.5-15.51410,504 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-05-29Sell17395,331$13.932.4-15.5195,331 (Direct)
Roach James M.Senior VP, Development and Chi2012-05-29Sell19278,619$13.932.7-15.5178,619 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-05-23Sell240103,681$13.93.3-15.32103,681 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2012-05-23Sell208410,686$13.92.9-15.32410,686 (Direct)
Roach James M.Senior VP, Development and Chi2012-05-23Sell18978,811$13.92.6-15.3278,811 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-05-23Sell18995,504$13.92.6-15.3295,504 (Direct)
WHEELER CRAIG APresident2012-05-23Sell2,109560,155$13.9829.5-15.81333,829 (Direct)
226,326 (Craig Wheeler revocable trust)
Leicher BruceSVP & General Counsel2012-05-23Sell189101,216$13.92.6-15.32101,216 (Direct)
Leicher BruceSVP & General Counsel2012-05-22Sell693101,405$14.249.9-17.35101,405 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-05-21Sell19295,693$13.872.7-15.1495,693 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-05-21Sell243103,921$13.873.4-15.14103,921 (Direct)
Roach James M.Senior VP, Development and Chi2012-05-21Sell19279,000$13.872.7-15.1479,000 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2012-05-21Sell211410,894$13.872.9-15.14410,894 (Direct)
WHEELER CRAIG APresident2012-05-21Sell2,110562,264$14.1529.9-16.82335,938 (Direct)
226,326 (Craig Wheeler revocable trust)
Shapiro Bennett MDirector2012-05-10Sell2,0007,000$13.9427.9-15.577,000 (Direct)
Roach James M.Senior VP, Development and Chi2012-04-19Sell15,00079,192$15.1226.5-22.0579,192 (Direct)
Shapiro Bennett MDirector2012-04-10Sell2,0007,000$15.3930.8-23.527,000 (Direct)
Shapiro Bennett MDirector2012-03-12Sell2,0007,000$15.0330.1-21.697,000 (Direct)
Leicher BruceSVP & General Counsel2012-02-28Sell135102,098$14.92-21.01102,098 (Direct)
WHEELER CRAIG APresident2012-02-28Sell2,109564,374$1531.6-21.53322,580 (Direct)
241,794 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-02-28Sell17395,885$14.92.6-21.0195,885 (Direct)
Roach James M.Senior VP, Development and Chi2012-02-28Sell19179,192$14.92.8-21.0179,192 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-02-28Sell284104,164$14.94.2-21.01104,164 (Direct)
Kaundinya Ganesh VenkataramanSenior V.P., Research2012-02-28Sell182411,105$14.92.7-21.01411,105 (Direct)
Leicher BruceSVP & General Counsel2012-02-24Sell708102,233$15.7111.1-25.08102,233 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2012-02-24Sell1,103104,448$15.7117.3-25.08104,448 (Direct)
Roach James M.Senior VP, Development and Chi2012-02-24Sell70879,383$15.7111.1-25.0879,383 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-02-24Sell70896,058$15.7111.1-25.0896,058 (Direct)
Venkataraman GaneshSenior V.P., Research2012-02-24Sell779411,287$15.7112.2-25.08411,287 (Direct)
WHEELER CRAIG APresident2012-02-23Sell12,657566,483$15.39194.8-23.52324,689 (Direct)
241,794 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2012-02-23Sell604105,551$15.149.1-22.26105,551 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2012-02-23Sell40996,766$15.146.2-22.2696,766 (Direct)
Venkataraman GaneshSenior V.P., Research2012-02-23Sell313412,066$15.134.7-22.21412,066 (Direct)
Roach James M.Senior VP, Development and Chi2012-02-22Sell19180,091$15.112.9-22.180,091 (Direct)
Leicher BruceSVP & General Counsel2012-02-22Sell692102,941$15.1110.5-22.1102,941 (Direct)
Shapiro Bennett MDirector2012-02-10Sell2,0007,000$15.4130.8-23.627,000 (Direct)
Shapiro Bennett MDirector2012-01-11Sell2,0007,000$19.3938.8-39.37,000 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-12-15Sell42695,682$15.926.8-26.0795,682 (Direct)
Shapiro Bennett MDirector2011-12-12Sell2,0007,000$15.4130.8-23.627,000 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-11-28Sell39290,175$14.975.9-21.3890,175 (Direct)
Leicher BruceSVP & General Counsel2011-11-28Sell13590,106$14.972-21.3890,106 (Direct)
Venkataraman GaneshSenior V.P., Research2011-11-28Sell285401,906$14.974.3-21.38401,906 (Direct)
WHEELER CRAIG APresident2011-11-28Sell4,220519,140$14.8762.8-20.85300,548 (Direct)
218,592 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2011-11-28Sell59396,108$14.978.9-21.3896,108 (Direct)
Roach James M.Senior VP, Development and Chi2011-11-28Sell19269,809$14.972.9-21.3869,809 (Direct)
Leicher BruceSVP & General Counsel2011-11-22Sell69490,241$14.8910.3-20.9590,241 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-11-22Sell2,49896,701$14.8837.2-20.996,701 (Direct)
Venkataraman GaneshSenior V.P., Research2011-11-21Sell212402,403$15.013.2-21.59402,403 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-11-21Sell19390,567$15.012.9-21.5990,567 (Direct)
Roach James M.Senior VP, Development and Chi2011-11-21Sell19370,001$15.012.9-21.5970,001 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-11-21Sell29996,701$15.014.5-21.5996,701 (Direct)
WHEELER CRAIG APresident2011-11-21Sell2,110523,360$14.8731.4-20.85304,768 (Direct)
218,592 (Craig Wheeler revocable trust)
Shapiro Bennett MDirector2011-11-10Sell2,0007,000$14.6329.3-19.557,000 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-09-15Sell42697,000$17.387.4-32.2897,000 (Direct)
Shapiro Bennett MDirector2011-09-12Sell2,0007,000$16.132.2-26.897,000 (Direct)
Stoner ElizabethDirector2011-09-01Sell1,3207,880$16.9422.4-30.527,880 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-08-26Sell17490,760$16.072.8-26.7690,760 (Direct)
Leicher BruceSVP & General Counsel2011-08-26Sell13690,935$16.072.2-26.7690,935 (Direct)
Venkataraman GaneshSenior V.P., Research2011-08-26Sell183402,403$16.072.9-26.76402,403 (Direct)
WHEELER CRAIG APresident2011-08-26Sell2,109525,470$16.2834.3-27.7355,861 (Direct)
169,609 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2011-08-26Sell28697,426$16.084.6-26.897,426 (Direct)
Roach James M.Senior VP, Development and Chi2011-08-26Sell19370,194$16.073.1-26.7670,194 (Direct)
WHEELER CRAIG APresident2011-08-23Sell2,109527,579$15.532.7-24.06357,970 (Direct)
169,609 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-08-23Sell21890,934$15.583.4-24.4590,934 (Direct)
Venkataraman GaneshSenior V.P., Research2011-08-23Sell102402,586$15.581.6-24.45402,586 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-08-23Sell2,80597,712$16.3445.8-27.9797,712 (Direct)
Leicher BruceSVP & General Counsel2011-08-22Sell69491,071$16.3511.3-28.0191,071 (Direct)
Venkataraman GaneshSenior V.P., Research2011-08-19Sell213402,688$15.673.3-24.89402,688 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-08-19Sell19491,152$15.673-24.8991,152 (Direct)
Roach James M.Senior VP, Development and Chi2011-08-19Sell19470,387$15.673-24.8970,387 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-08-19Sell30298,019$15.674.7-24.8998,019 (Direct)
WHEELER CRAIG APresident2011-08-19Sell2,109529,688$15.9733.7-26.3360,079 (Direct)
169,609 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-08-16Sell30491,346$17.115.2-31.2191,346 (Direct)
Shapiro Bennett MDirector2011-08-10Sell8007,000$16.0712.9-26.767,000 (Direct)
Shapiro Bennett MDirector2011-07-11Sell1,2007,000$20.5324.6-42.677,000 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-07-07Sell4,98798,321$20.92104.3-43.7498,321 (Direct)
Venkataraman GaneshSenior V.P., Research2011-07-05Sell15,900387,001$20.35323.6-42.16387,001 (Direct)
WHEELER CRAIG APresident2011-07-05Sell6,700531,797$20.15135-41.59364,766 (Direct)
167,031 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2011-06-15Sell42998,321$18.177.8-35.2298,321 (Direct)
Shapiro Bennett MDirector2011-06-10Sell2,0007,000$19.0338.1-38.157,000 (Direct)
WHEELER CRAIG APresident2011-06-08Sell14,200531,797$20.19286.7-41.7364,766 (Direct)
167,031 (Craig Wheeler revocable trust)
Venkataraman GaneshSenior V.P., Research2011-06-08Sell9,100402,901$20.36185.3-42.19402,901 (Direct)
Stoner ElizabethDirector2011-06-01Sell9006,700$20.1118.1-41.476,700 (Direct)
WHEELER CRAIG APresident2011-05-31Sell12,100536,397$20.16243.9-41.62364,766 (Direct)
171,631 (Craig Wheeler revocable trust)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-05-26Sell17291,019$19.23.3-38.791,019 (Direct)
Roach James M.Senior VP, Development and Chi2011-05-26Sell19170,581$19.23.7-38.770,581 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-05-26Sell28498,750$19.25.5-38.798,750 (Direct)
Venkataraman GaneshSenior V.P., Research2011-05-26Sell182412,001$19.23.5-38.7412,001 (Direct)
Leicher BruceSVP & General Counsel2011-05-26Sell13590,965$19.22.6-38.790,965 (Direct)
WHEELER CRAIG APresident2011-05-26Sell2,110541,797$19.240.5-38.7380,235 (Direct)
161,562 (Craig Wheeler revocable trust)
Bishop John ESenior VP, Pharmaceutical Scie2011-05-24Sell2,80599,034$18.3251.4-35.7599,034 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-05-24Sell21791,191$18.694.1-37.0391,191 (Direct)
Venkataraman GaneshSenior V.P., Research2011-05-24Sell102412,183$18.691.9-37.03412,183 (Direct)
WHEELER CRAIG APresident2011-05-24Sell2,110543,907$18.6939.4-37.03543,907 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-05-20Sell19491,408$18.553.6-36.5591,408 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-05-20Sell30199,341$18.555.6-36.5599,341 (Direct)
Venkataraman GaneshSenior V.P., Research2011-05-20Sell213412,285$18.554-36.55412,285 (Direct)
Roach James M.Senior VP, Development and Chi2011-05-20Sell19470,772$18.553.6-36.5570,772 (Direct)
Leicher BruceSVP & General Counsel2011-05-20Sell69591,100$18.5512.9-36.5591,100 (Direct)
WHEELER CRAIG APresident2011-05-19Sell2,109546,017$18.4238.8-36.1546,017 (Direct)
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-05-17Sell30191,602$18.785.7-37.3391,602 (Direct)
Shapiro Bennett MDirector2011-05-10Sell2,0007,000$19.1938.4-38.677,000 (Direct)
Bishop John ESenior VP, Pharmaceutical Scie2011-04-26Sell7,0340$18.86132.7-37.59Link
Shapiro Bennett MDirector2011-04-11Sell2,0000$15.2930.6-23.02Link
Bishop John ESenior VP, Pharmaceutical Scie2011-03-18Sell2,4970$14.8837.2-20.9Link
Bishop John ESenior VP, Pharmaceutical Scie2011-03-15Sell4360$13.946.1-15.57Link
Shapiro Bennett MDirector2011-03-10Sell2,0000$13.9928-15.87Link
Stoner ElizabethDirector2011-03-01Sell1,5600$13.521.1-12.81Link
Leicher BruceSVP & General Counsel2011-02-28Sell1350$13.851.9-15.02Link
WHEELER CRAIG APresident2011-02-28Sell2,1090$13.8229.1-14.83Link
Bishop John ESenior VP, Pharmaceutical Scie2011-02-28Sell2840$13.853.9-15.02Link
Roach James M.Senior VP, Development and Chi2011-02-28Sell1920$13.852.7-15.02Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-02-28Sell1730$13.852.4-15.02Link
Venkataraman GaneshSenior V.P., Research2011-02-28Sell1820$13.852.5-15.02Link
Leicher BruceSVP & General Counsel2011-02-23Sell1,2620$13.3716.9-11.97Link
WHEELER CRAIG APresident2011-02-23Sell10,5460$13.36140.9-11.9Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-02-23Sell9790$13.4113.1-12.23Link
Venkataraman GaneshSenior V.P., Research2011-02-23Sell9390$13.4312.6-12.36Link
Bishop John ESenior VP, Pharmaceutical Scie2011-02-23Sell1,4930$13.4120-12.23Link
Roach James M.Senior VP, Development and Chi2011-02-22Sell7610$13.4510.2-12.49Link
Stoner ElizabethDirector2011-02-16Sell8,3400$13.4111.8-12.16Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2011-02-16Sell3010$13.624.1-13.58Link
Shapiro Bennett MDirector2011-02-10Sell2,0000$13.5827.2-13.33Link
Bishop John ESenior VP, Pharmaceutical Scie2010-12-16Sell85246,657$14.6312.5-19.55Link
HUTT PETER BARTONDirector2010-12-14Sell126,4985,365$14.511835.5-18.88Link
Leicher BruceSVP & General Counsel2010-11-29Sell13538,144$15.222.1-22.67Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-11-29Sell17339,085$15.222.6-22.67Link
Roach James M.Senior VP, Development and Chi2010-11-29Sell19217,648$15.222.9-22.67Link
Bishop John ESenior VP, Pharmaceutical Scie2010-11-29Sell28547,509$15.224.3-22.67Link
Venkataraman GaneshSenior V.P., Research2010-11-29Sell182358,421$15.222.8-22.67Link
WHEELER CRAIG APresident2010-11-29Sell2,110338,281$15.3232.3-23.17Link
Venkataraman GaneshSenior V.P., Research2010-11-23Sell102358,603$15.21.6-22.57Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-11-23Sell21839,258$15.23.3-22.57Link
WHEELER CRAIG APresident2010-11-23Sell2,110340,391$15.0731.8-21.9Link
Bishop John ESenior VP, Pharmaceutical Scie2010-11-23Sell2,80747,794$15.3143-23.12Link
Leicher BruceSVP & General Counsel2010-11-22Sell50138,279$15.457.7-23.82Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-11-16Sell30339,476$15.824.8-25.6Link
Venkataraman GaneshSenior V.P., Research2010-09-17Sell15,000326,705$15.06225.9-21.85Link
Bishop John ESenior VP, Pharmaceutical Scie2010-09-16Sell85248,103$15.3113-23.12Link
WHEELER CRAIG APresident2010-08-27Sell2,109342,501$15.8533.4-25.74Link
Leicher BruceSVP & General Counsel2010-08-26Sell13538,780$16.572.2-28.97Link
Venkataraman GaneshSenior V.P., Research2010-08-26Sell182341,705$16.573-28.97Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-08-26Sell17239,779$16.572.9-28.97Link
Roach James M.Senior VP, Development and Chi2010-08-26Sell19217,840$16.573.2-28.97Link
Brugger Stephen BCOO2010-08-26Sell457209,188$16.577.6-28.97Link
Bishop John ESenior VP, Pharmaceutical Scie2010-08-26Sell28448,955$16.574.7-28.97Link
WHEELER CRAIG APresident2010-08-24Sell47,109344,610$15.21716.5-22.62Link
Bishop John ESenior VP, Pharmaceutical Scie2010-08-24Sell31049,239$15.224.7-22.67Link
Brugger Stephen BCOO2010-08-24Sell134209,645$15.222-22.67Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-08-24Sell21939,951$15.223.3-22.67Link
Venkataraman GaneshSenior V.P., Research2010-08-24Sell103341,887$15.221.6-22.67Link
Bishop John ESenior VP, Pharmaceutical Scie2010-08-23Sell2,49849,549$16.0840.2-26.8Link
Leicher BruceSVP & General Counsel2010-08-20Sell50138,915$15.767.9-25.32Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-08-17Sell30140,170$16.545-28.84Link
WHEELER CRAIG APresident2010-08-09Sell36,922391,719$17.79656.8-33.84Link
Venkataraman GaneshSenior V.P., Research2010-08-06Sell22,300341,990$17.69394.5-33.47Link
Venkataraman GaneshSenior V.P., Research2010-08-05Sell17,700364,290$21.43379.3-45.08Link
Brugger Stephen BCOO2010-08-05Sell45,296209,779$20.46926.8-42.47Link
WHEELER CRAIG APresident2010-08-05Sell41,828428,641$21.18885.9-44.43Link
Venkataraman GaneshSenior V.P., Research2010-07-26Sell20,000381,990$24.25485-51.46Link
Sasisekharan RamDirector2010-07-26Sell33,930306,344$22.99780.1-48.8Link
Venkataraman GaneshSenior V.P., Research2010-07-23Sell40,000401,990$21.38855.2-44.95Link
Sasisekharan RamDirector2010-07-23Sell41,070340,274$21.17869.5-44.4Link
Bishop John ESenior VP, Pharmaceutical Scie2010-06-17Sell2,49849,549$14.8837.2-20.9Link
Bishop John ESenior VP, Pharmaceutical Scie2010-06-16Sell42949,549$13.695.9-14.02Link
Bishop John ESenior VP, Pharmaceutical Scie2010-06-15Sell42649,978$146-15.93Link
Leicher BruceSVP & General Counsel2010-05-26Sell13538,734$12.451.7-5.46Link
WHEELER CRAIG APresident2010-05-26Sell2,109470,469$12.6226.6-6.74Link
Brugger Stephen BCOO2010-05-26Sell457255,075$12.455.7-5.46Link
Bishop John ESenior VP, Pharmaceutical Scie2010-05-26Sell28450,404$12.453.5-5.46Link
Venkataraman GaneshSenior V.P., Research2010-05-26Sell182441,990$12.452.3-5.46Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-05-26Sell17340,471$12.452.2-5.46Link
Roach James M.Senior VP, Development and Chi2010-05-26Sell96818,032$14.2113.8-17.17Link
WHEELER CRAIG APresident2010-05-25Sell2,110472,578$11.9225.2-1.26Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-05-25Sell22240,644$11.562.61.82Link
Bishop John ESenior VP, Pharmaceutical Scie2010-05-25Sell31450,688$11.563.61.82Link
Brugger Stephen BCOO2010-05-25Sell136255,532$11.561.61.82Link
Venkataraman GaneshSenior V.P., Research2010-05-25Sell104442,172$11.561.21.82Link
Leicher BruceSVP & General Counsel2010-05-20Sell50938,869$12.666.4-7.03Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-05-18Sell30240,866$13.414-12.23Link
Bishop John ESenior VP, Pharmaceutical Scie2010-03-17Sell59251,002$14.598.6-19.33Link
Brugger Stephen BCOO2010-03-10Sell7,800255,668$15.13118-22.21Link
Brugger Stephen BCOO2010-03-09Sell32,200263,468$15.17488.5-22.41Link
Venkataraman GaneshSenior V.P., Research2010-03-09Sell32,462442,276$14.83481.4-20.63Link
Leicher BruceSVP & General Counsel2010-03-01Sell54339,378$14.658-19.66Link
Brugger Stephen BCOO2010-03-01Sell1,413295,668$14.6520.7-19.66Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-03-01Sell69841,168$14.6510.2-19.66Link
Venkataraman GaneshSenior V.P., Research2010-03-01Sell737474,738$14.6510.8-19.66Link
Bishop John ESenior VP, Pharmaceutical Scie2010-03-01Sell1,15351,594$14.6516.9-19.66Link
WHEELER CRAIG APresident2010-02-26Sell8,438474,688$14.67123.8-19.77Link
Leicher BruceSVP & General Counsel2010-02-23Sell50839,921$15.097.7-22Link
Brugger Stephen BCOO2010-02-23Sell102297,081$15.091.5-22Link
Venkataraman GaneshSenior V.P., Research2010-02-23Sell102475,475$15.091.5-22Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-02-23Sell21841,866$15.093.3-22Link
WHEELER CRAIG APresident2010-02-23Sell2,109483,126$15.0531.7-21.79Link
Bishop John ESenior VP, Pharmaceutical Scie2010-02-23Sell30252,747$15.094.6-22Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2010-02-17Sell33632,584$15.195.1-22.51Link
Sasisekharan RamDirector2010-01-22Sell25,000381,344$15.01375.3-21.59Link
Bishop John ESenior VP, Pharmaceutical Scie2009-12-15Sell30242,100$11.163.45.47Link
Bishop John ESenior VP, Pharmaceutical Scie2009-12-14Sell37542,402$11.094.26.13Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2009-11-24Sell21832,911$10.532.311.78Link
WHEELER CRAIG APresident2009-11-24Sell2,109410,235$10.5322.211.78Link
Venkataraman GaneshSenior V.P., Research2009-11-24Sell205465,136$10.182.115.62Link
Brugger Stephen BCOO2009-11-24Sell205279,858$10.182.115.62Link
Bishop John ESenior VP, Pharmaceutical Scie2009-11-23Sell27042,777$10.492.812.2Link
Leicher BruceSVP & General Counsel2009-11-19Sell1,56228,091$11.2917.64.25Link
Leicher BruceSVP & General Counsel2009-11-19Sell50129,152$11.255.64.62Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2009-11-16Sell30333,129$10.283.114.49Link
Bishop John ESenior VP, Pharmaceutical Scie2009-09-15Sell67343,047$10.38713.39Link
WHEELER CRAIG APresident2009-08-25Sell2,109412,344$9.8220.719.86Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2009-08-24Sell21833,432$9.822.119.86Link
Bishop John ESenior VP, Pharmaceutical Scie2009-08-24Sell27043,720$9.92.718.89Link
Leicher BruceSVP & General Counsel2009-08-19Sell1,99729,653$9.9719.918.05Link
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2009-08-17Sell30233,650$9.692.921.47Link
Bishop John ESenior VP, Pharmaceutical Scie2009-06-15Sell67743,990$9.086.129.63
WHEELER CRAIG APresident2009-05-26Sell2,109414,453$8.4117.739.95
Brugger Stephen BCOO2009-05-22Sell100280,089$8.520.938.15
Venkataraman GaneshSenior V.P., Research2009-05-22Sell100465,340$8.520.938.15
Bishop John ESenior VP, Pharmaceutical Scie2009-05-22Sell27044,667$8.712.435.13
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2009-05-22Sell21533,952$8.521.838.15
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2009-05-15Sell30234,167$9.42.825.21
Bishop John ESenior VP, Pharmaceutical Scie2009-03-20Sell25844,937$9.322.426.29
Bishop John ESenior VP, Pharmaceutical Scie2009-03-16Sell37545,195$8.333.141.3
WHEELER CRAIG APresident2009-02-24Sell8,438341,562$10.6189.510.93
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2009-02-23Sell85825,919$10.569.111.46
Venkataraman GaneshSenior V.P., Research2009-02-23Sell397456,415$10.564.211.46
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2009-02-17Sell36026,777$11.764.20.09
Venkataraman GaneshSenior V.P., Research2009-01-16Sell7,489456,812$1289.9-1.92
Venkataraman GaneshSenior V.P., Research2009-01-06Sell2,006464,301$1224.1-1.92
Venkataraman GaneshSenior V.P., Research2008-12-17Sell10,505466,307$12.02126.3-2.08
Bishop John ESenior VP, Pharmaceutical Scie2008-12-15Sell1,87536,675$10.5619.811.46
Shea Richard PSVP, CFO
(Click for the stocks that their CFOs have bought)
2008-11-19Sell37127,137$7.772.951.48
LANGER ROBERTDirector2008-08-08Sell20,000950,022$16.81336.2-29.98
Bishop John ESenior VP, Pharmaceutical Scie2008-08-06Sell28,50038,550$18513-34.61
Bishop John ESenior VP, Pharmaceutical Scie2008-06-16Sell37538,550$13.225-10.97
Bishop John ESenior VP, Pharmaceutical Scie2008-04-24Sell9,37538,925$13121.9-9.46
Bishop John ESenior VP, Pharmaceutical Scie2008-03-17Sell35738,925$9.213.327.8
Bishop John ESenior VP, Pharmaceutical Scie2007-12-17Sell1,50028,500$7.1810.863.93
Sasisekharan RamDirector2007-10-15Sell10,000406,344$12.57125.7-6.36
Sasisekharan RamDirector2007-09-17Sell10,000416,344$11.17111.75.37
Sasisekharan RamDirector2007-08-15Sell10,000402,344$10.48104.812.31
Sasisekharan RamDirector2007-07-16Sell10,000412,344$10.44104.412.74
Sasisekharan RamDirector2007-06-15Sell10,000422,344$12.12121.2-2.89
Sasisekharan RamDirector2007-05-15Sell10,000432,344$12.04120.4-2.24
Whoriskey Susan KV.P., Lic. & Bus. Dev.2007-04-17Sell6,66668,831$14.9199.4-21.06
Sasisekharan RamDirector2007-04-16Sell9,000442,344$14.62131.6-19.49
Sasisekharan RamDirector2007-03-15Sell10,000452,344$12.34123.4-4.62
Sasisekharan RamDirector2007-02-15Sell10,000462,344$14.05140.5-16.23
Lisa Carron ShmerlingV.P., Legal Affairs2007-02-08Sell11,2500$21236.3-43.95
Shapiro Bennett MDirector2007-01-17Sell9,0006,000$17.41156.7-32.4
Shapiro Bennett MDirector2007-01-17Sell9,0007,000$15135-21.53
Whoriskey Susan KV.P., Lic. & Bus. Dev.2007-01-16Sell6,66675,497$16.95113-30.56
Sasisekharan RamDirector2007-01-16Sell10,000472,344$17.67176.7-33.39
Crane Alan LDirector2007-01-10Sell49,700586,342$17.46867.8-32.59
Whoriskey Susan KV.P., Lic. & Bus. Dev.2006-12-19Sell6,66682,163$15.92106.1-26.07
Crane Alan LDirector2006-12-18Sell62,500636,342$16.461028.8-28.49
Shapiro Bennett MDirector2006-12-18Sell9,0005,000$16.74150.7-29.69
Sasisekharan RamDirector2006-12-15Sell10,000482,344$16.93169.3-30.48
Crane Alan LDirector2006-12-08Sell50,000698,842$17.59879.5-33.09
Whoriskey Susan KV.P., Lic. & Bus. Dev.2006-11-21Sell6,66688,829$17.46116.4-32.59
Shapiro Bennett MDirector2006-11-16Sell9,0004,000$16.64149.8-29.27
Crane Alan LDirector2006-11-16Sell61,200748,842$16.33999.4-27.92
Sasisekharan RamDirector2006-11-15Sell10,000492,344$16.07160.7-26.76
Crane Alan LDirector2006-11-08Sell50,000811,342$15.22761-22.67
Shapiro Bennett MDirector2006-10-18Sell9,0003,000$15.05135.5-21.79
Whoriskey Susan KV.P., Lic. & Bus. Dev.2006-10-17Sell6,66695,495$15.66104.4-24.84
Sasisekharan RamDirector2006-10-16Sell9,700502,644$15.24147.8-22.77
Sasisekharan RamDirector2006-10-16Sell300502,344$15.644.7-24.74
Crane Alan LDirector2006-10-13Sell30,2321,061,342$15453.5-21.53
Crane Alan LDirector2006-10-11Sell19,7861,091,574$15296.8-21.53
Crane Alan LDirector2006-10-11Sell20,0561,091,304$15300.8-21.53
Venkataraman GaneshSenior V.P., Research2006-10-03Sell10,000452,812$13.3133-11.5
Shapiro Bennett MDirector2006-09-20Sell9,0002,000$15135-21.53Link
Whoriskey Susan KV.P., Lic. & Bus. Dev.2006-09-19Sell6,666102,161$15.03100.2-21.69Link
Sasisekharan RamDirector2006-09-15Sell10,000512,344$15.2152-22.57Link
Venkataraman GaneshSenior V.P., Research2006-09-13Sell100,000462,812$15.051505-21.79Link
Crane Alan LC.E.O.2006-09-12Sell88,1741,111,360$15.011323.5-21.59Link
Crane Alan LC.E.O.2006-09-07Sell12,4021,161,360$15.35190.4-23.32Link
Crane Alan LC.E.O.2006-09-05Sell21,6001,161,360$15.9343.4-25.97Link
Venkataraman GaneshSenior V.P., Research2006-09-01Sell10,000562,812$15.95159.5-26.21Link
Crane Alan LPresident, C.E.O.2006-08-31Sell83,0001,161,360$16.411362-28.28Link
Shapiro Bennett MDirector2006-08-18Sell9,0001,000$15.04135.4-21.74Link
Sasisekharan RamDirector2006-08-15Sell10,000522,344$13.91139.1-15.38Link
Crane Alan LPresident, C.E.O.2006-08-09Sell29,7001,161,360$15.24452.6-22.77Link
Crane Alan LPresident, C.E.O.2006-08-08Sell20,3001,191,060$15.61316.9-24.6Link
Venkataraman GaneshSenior V.P., Research2006-08-03Sell2,500572,812$16.9342.3-30.48Link
Venkataraman GaneshSenior V.P., Research2006-08-02Sell7,500575,312$17.05127.9-30.97Link
Bishop John EVP Pharma Sciences & Manufact2006-07-25Sell1,5000$2030-41.15Link
Sasisekharan RamDirector2006-07-17Sell10,000532,344$11.71117.10.51Link
Venkataraman GaneshSenior V.P., Research2006-07-06Sell10,000582,812$12.73127.3-7.54Link
Sasisekharan RamDirector2006-06-15Sell10,000542,344$13.07130.7-9.95Link
Venkataraman GaneshSenior V.P., Research2006-06-05Sell4,000592,812$13.754.8-14.09Link
Venkataraman GaneshSenior V.P., Research2006-06-01Sell6,000596,812$14.0884.5-16.41Link
Whoriskey Susan KV.P., Lic. & Bus. Dev.2006-05-16Sell5,821108,496$14.584.4-18.83Link
Sasisekharan RamDirector2006-05-15Sell10,000552,344$14.52145.2-18.94Link
Venkataraman GaneshSenior VP, Research2006-05-03Sell30,000602,812$15.83474.9-25.65Link
Sasisekharan RamDirector2006-04-24Sell34,300562,344$16.44563.9-28.41Link
Sasisekharan RamDirector2006-04-21Sell88,600596,644$171506.2-30.76Link
Sasisekharan RamDirector2006-04-20Sell77,100685,244$16.771293-29.82Link
Brugger Stephen BSenior Vice President2006-02-17Sell29,97058,386$24.51734.6-51.98Link
Bishop John EVP Pharma Sciences & Manufact2006-02-17Sell21,8750$24.65539.2-52.25Link
Sasisekharan RamDirector2005-12-15Sell16,000762,344$25.2403.2-53.29Link
Venkataraman GaneshSenior V.P., Research2005-12-01Sell6,000500,312$22.08132.5-46.69Link
Sasisekharan RamDirector2005-11-15Sell16,000778,344$20.95335.2-43.82Link
Venkataraman GaneshSenior V.P., Research2005-11-01Sell6,000506,312$21.56129.4-45.41Link
Sasisekharan RamDirector2005-10-17Sell16,000794,344$26.06417-54.83Link
Venkataraman GaneshSenior V.P., Research2005-10-03Sell6,000512,312$28.79172.7-59.12Link
Sasisekharan RamDirector2005-09-15Sell15,800810,544$27.3431.3-56.89Link
Sasisekharan RamDirector2005-09-15Sell200810,344$27.965.6-57.9Link
Venkataraman GaneshSenior V.P., Research2005-09-01Sell6,000518,312$25.32151.9-53.52Link
Sasisekharan RamDirector2005-08-15Sell16,000826,344$22.33357.3-47.29Link
Venkataraman GaneshSenior V.P., Research2005-08-01Sell6,000524,312$25.39152.3-53.64Link
Sasisekharan RamDirector2005-07-15Sell16,000842,344$23.39374.2-49.68Link
Venkataraman GaneshSenior V.P., Research2005-07-01Sell6,000530,312$19.61117.7-39.98Link
Sasisekharan RamDirector2005-06-23Sell19,000858,344$20.65392.4-43Link
Venkataraman GaneshSenior V.P., Research2005-06-16Sell10,500536,312$17178.5-30.76Link
Sasisekharan RamDirector2005-06-16Sell54,000877,344$12.83692.8-8.26Link
Venkataraman GaneshSenior V.P., Research2005-06-01Sell6,000546,812$11.5369.22.08Link
Venkataraman GaneshSenior V.P., Research2005-05-26Sell10,000552,812$111107Link
Sasisekharan RamDirector2005-05-23Sell19,000931,344$1019017.7Link
Sasisekharan RamDirector2005-05-16Sell16,000950,344$9.5615323.12Link
Venkataraman GaneshSenior V.P., Research2005-05-09Sell10,500562,812$9.55100.323.25Link
Sasisekharan RamDirector2005-05-06Sell19,000966,344$8.6316436.38Link
Venkataraman GaneshSenior V.P., Research2005-05-04Sell9,600573,312$8.2879.542.15Link
Venkataraman GaneshSenior VP, Research2005-05-03Sell6,400582,912$7.7349.552.26Link
CLARKE JOHN KDirector2005-03-08Buy35,8002,242,586$8.5230538.15Link
CLARKE JOHN KDirector2005-03-01Buy36,5002,206,786$8.03293.146.58Link
POLARIS VENTURE MANAGEMENT CO 10% Owner2005-02-22Sell250,00072,923$7.02175567.66Link
POLARIS VENTURE MANAGEMENT CO 10% Owner2004-06-25Buy160,00076,648$6.5104081.08Link
Westphal Christoph HDirector2004-06-25Buy160,00076,648$6.5104081.08Link
CLARKE JOHN KDirector2004-06-25Buy69,0002,170,286$6.5448.581.08Link
ATLAS VENTURE FUND V LP10% Owner2004-06-21Buy244,00073,201$6.5158681.08Link
Barrett PeterDirector, 10% Owner2004-06-21Buy122,0002,134$6.579381.08Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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