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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Randal W. Scott,PhDN/A1,185,1173.59%2012-07-10
Steven Shak,M.D.Chief Scientific Officer326,3830.99%2016-05-04
Joffre B. Baker,PhDN/A132,8460.4%2012-02-15
Dr. Fred E. Cohen,M.D.,D.Phil.N/A64,5200.2%2016-04-01
Kimberly J. PopovitsN/A58,7960.18%2016-02-15
G. Bradley ColeCOO34,9700.11%2016-05-16
Mr. James J. VaughnChief Commercial Officer31,255less than 0.1%2016-05-09
Mr. Frederic PlaN/A25,618less than 0.1%2016-02-15
Mr. Dean L. SchornoN/A24,524less than 0.1%2014-06-10
Brook H. ByersN/A23,951less than 0.1%2010-12-09

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Cole G BradleyCOO2016-05-16Sell5,00034,970$27.6138-3.6234,970 (Direct)
Febbo Phillip G.Chief Medical Officer2016-05-10Sell6,32415,013$27.2172-2.2115,013 (Direct)
Vaughn James JChief Commercial Officer2016-05-09Sell2,00031,255$2856-531,255 (Direct)
Shak StevenChief Scientific Officer2016-05-04Sell10,000326,383$25.43254.34.6326,383 (Direct)
Vaughn James JChief Commercial Officer2016-02-09Sell324,076$280.1-524,076 (Direct)
LIVINGSTON RANDALL SDirector2016-01-13Sell1,2506,149$32.1440.2-17.246,149 (Direct)
Cole G BradleyCOO2016-01-12Sell4,00027,428$31.69126.8-16.0627,428 (Direct)
Vaughn James JChief Commercial Officer2016-01-07Sell2,00024,076$33.6367.3-20.924,076 (Direct)
Cole G BradleyCOO2015-12-08Sell4,00027,428$29.26117-9.0927,428 (Direct)
Leber LauraChief Communication Officer2015-12-07Sell4,20012,959$29.33123.2-9.3112,959 (Direct)
Vaughn James JChief Commercial Officer2015-12-07Sell2,00024,076$29.3358.7-9.3124,076 (Direct)
Cole G BradleyCOO2015-11-10Sell4,00030,326$26.03104.12.1930,326 (Direct)
Cole G BradleyCOO2015-09-09Sell9,66430,326$25.352454.9330,326 (Direct)
Cole G BradleyCOO2015-07-07Sell4,00030,326$27.53110.1-3.3830,326 (Direct)
Cole G BradleyCOO2015-06-09Sell4,00030,326$26.241051.3730,326 (Direct)
Cole G BradleyCOO2015-05-12Sell4,00029,658$27.54110.2-3.4129,658 (Direct)
Popovits Kimberly JPresident and CEO
(Click for the stocks that their CEOs have bought)
2015-04-13Sell3,000203,001$31.2893.8-14.96Link
Cole G BradleyCOO2015-04-07Sell4,00029,658$30.44121.8-12.6129,658 (Direct)
Popovits Kimberly JPresident and CEO2015-03-12Sell3,000204,101$31.9195.7-16.64Link
Cole G BradleyCOO2015-03-10Sell4,00029,658$31.84127.4-16.4629,658 (Direct)
Popovits Kimberly JPresident and CEO2015-02-12Sell3,000204,601$29.8689.6-10.92Link
Cole G BradleyCOO2015-02-10Sell4,00021,645$31.37125.5-15.2121,645 (Direct)
LIVINGSTON RANDALL SDirector2015-02-02Sell1,0006,149$31.9331.9-16.696,149 (Direct)
Popovits Kimberly JPresident and CEO2015-01-12Sell3,000204,601$33.46100.4-20.5Link
Popovits Kimberly JPresident and CEO2014-12-11Sell3,000204,601$32.9999-19.37Link
Cole G BradleyCOO2014-12-08Sell4,33621,645$32.52141-18.221,645 (Direct)
Popovits Kimberly JPresident and CEO2014-11-12Sell4,300205,201$34.82149.7-23.61Link
Cole G BradleyCOO2014-11-10Sell4,00022,891$35.35141.4-24.7522,891 (Direct)
LIVINGSTON RANDALL SDirector2014-11-03Sell3,0006,149$36.24108.7-26.66,149 (Direct)
Popovits Kimberly JPresident and CEO2014-10-13Sell3,000205,201$30.7892.3-13.58Link
Cole G BradleyCOO2014-10-08Sell4,00022,891$28.77115.1-7.5422,891 (Direct)
Popovits Kimberly JPresident and CEO2014-09-11Sell3,000205,201$29.8289.5-10.8Link
Cole G BradleyCOO2014-09-08Sell4,70022,891$30.09141.4-11.622,891 (Direct)
Shak StevenEVP of R&D2014-08-14Sell13,348312,298$27.36365.2-2.78312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-08-12Sell3,000205,201$26.0778.22.03Link
Popovits Kimberly JPresident and CEO2014-07-14Sell3,000205,201$26.5979.80.04Link
Cole G BradleyCOO2014-07-08Sell2,30022,891$27.0562.2-1.6622,891 (Direct)
Shak StevenEVP of R&D2014-07-01Sell7,000312,298$27189-1.48312,298 (Direct)
Shak StevenEVP of R&D2014-06-12Sell7,000312,298$26.73187.1-0.49312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-06-12Sell3,000271,289$26.178.31.92Link
Schorno Dean LCFO2014-06-10Sell4,00030,673$27.62110.5-3.6924,524 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2014-06-09Sell2,33722,891$27.2963.8-2.5322,891 (Direct)
Popovits Kimberly JPresident and CEO2014-05-12Sell3,000270,579$26.5479.60.23Link
Schorno Dean LCFO2014-05-09Sell4,00029,963$25.09100.46.0223,814 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Shak StevenEVP of R&D2014-04-14Sell7,000311,588$26.25183.81.33311,588 (Direct)
Cole G BradleyCOO2014-04-08Sell3,00022,226$2781-1.4822,226 (Direct)
Shak StevenEVP of R&D2014-03-14Sell7,000311,588$28.36198.5-6.21311,588 (Direct)
Cole G BradleyCOO2014-03-10Sell3,00022,226$27.7683.3-4.1822,226 (Direct)
HIBBS KATHY LSVP & General Counsel2014-02-18Sell1,31215,787$27.8836.6-4.5915,787 (Direct)
Shak StevenEVP of R&D2014-02-14Sell7,000311,588$27.38191.7-2.85311,588 (Direct)
Cole G BradleyCOO2014-02-10Sell3,00024,789$2781-1.4824,789 (Direct)
Shak StevenEVP of R&D2014-01-15Sell7,000308,283$31.51220.6-15.58308,283 (Direct)
Popovits Kimberly JPresident and CEO2014-01-13Sell2,500261,190$3075-11.33Link
Cole G BradleyCOO2014-01-08Sell3,00018,369$28.1784.5-5.5718,369 (Direct)
Shak StevenEVP of R&D & CMO2013-12-17Sell14,000308,283$29.57414-10.04308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-12-12Sell2,5000$30.6876.7-13.3Link
Schorno Dean LCFO2013-12-09Sell3,00027,706$33.2599.8-2021,557 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-12-02Sell1,0006,149$34.9234.9-23.836,149 (Direct)
Popovits Kimberly JPresident and CEO2013-11-13Sell5,0000$34.58172.9-23.08Link
Schorno Dean LCFO2013-11-08Sell3,00027,585$33.36100.1-20.2621,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-11-06Sell2,86818,135$31.3890-15.2318,135 (Direct)
Shak StevenEVP of R&D & CMO2013-10-15Sell5,000308,283$29.67148.4-10.35308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-10-10Sell2,5000$3075-11.33Link
Cole G BradleyCOO2013-10-09Sell2,50018,135$29.9574.9-11.1918,135 (Direct)
Shak StevenEVP of R&D & CMO2013-09-18Sell5,000313,283$33.73168.7-21.14313,283 (Direct)
Popovits Kimberly JPresident and CEO2013-09-12Sell2,5000$34.3185.8-22.47Link
Cole G BradleyCOO2013-09-09Sell2,50018,135$32.5381.3-18.2318,135 (Direct)
Schorno Dean LCFO2013-09-06Sell4,00027,585$32.9131.6-19.1521,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-09-03Sell1,0006,149$31.4931.5-15.536,149 (Direct)
Shak StevenEVP of R&D & CMO2013-08-14Sell5,000318,283$32.98164.9-19.35318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-08-12Sell2,5000$33.0382.6-19.47Link
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-19.7621,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-19.7621,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-08-07Sell2,50019,135$33.6684.2-20.9719,135 (Direct)
Shak StevenEVP of R&D & CMO2013-07-23Sell5,000318,283$35.33176.7-24.71318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-07-12Sell5,0000$34.61173.1-23.14Link
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.2-21.3317,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.2-21.3317,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-07-08Sell2,50013,135$33.3383.3-20.1913,135 (Direct)
Shak StevenEVP of R&D & CMO2013-06-18Sell5,000323,283$33.52167.6-20.64323,283 (Direct)
Popovits Kimberly JPresident and CEO2013-06-12Sell5,0000$35.68178.4-25.45Link
Schorno Dean LCFO2013-06-10Sell4,00023,985$35.88143.5-25.8617,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER FELIXDirector, 10% Owner2013-06-05Buy381,43213,288,253$36.1613792.6-26.44
1,730,777 (See Footnote)
11,241,654 (See Footnotes(F7,F14,F15))
301,215 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-06-05Sell2,50013,135$36.4791.2-27.0613,135 (Direct)
BAKER FELIXDirector, 10% Owner2013-06-03Buy179,58312,906,821$36.716592.5-27.54
1,690,226 (See Footnote)
10,909,066 (See Footnotes(F7,F14,F15))
292,922 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-06-03Sell1,0006,149$36.436.4-26.926,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-29Buy121,26612,727,238$36.894473.5-27.89
1,671,081 (See Footnote)
10,752,532 (See Footnotes(F7,F14,F15))
289,018 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-05-24Buy79,41714,257,273$36.932932.9-27.97
1,651,301 (See Footnote)
10,646,920 (See Footnotes(F7,F17,F18))
286,384 (See Footnotes(F9,F17,F18))
1,658,061 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-22Sell1,0007,087$37.4837.5-29.037,087 (Direct)
Shak StevenEVP of R&D & CMO2013-05-21Sell5,000327,380$37.19186-28.48327,380 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-16Buy71,43912,526,555$36.452604-27.02
1,649,473 (See Footnote)
10,577,816 (See Footnotes(F7,F14,F15))
284,659 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-05-15Sell1,3376,149$35.8347.9-25.766,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-14Buy240,42614,093,759$34.348256.2-22.54
1,638,643 (See Footnote)
10,515,769 (See Footnotes(F7,F17,F18))
283,112 (See Footnotes(F9,F17,F18))
1,641,628 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-13Sell1,2507,087$34.4243-22.727,087 (Direct)
Popovits Kimberly JPresident and CEO2013-05-13Sell5,0000$34.7173.5-23.34Link
Schorno Dean LCFO2013-05-09Sell4,00023,241$36.02144.1-26.1517,092 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-05-08Sell2,50012,540$35.9990-26.0912,540 (Direct)
Popovits Kimberly JPresident and CEO2013-04-23Sell2,5000$3075-11.33Link
Cole G BradleyCOO2013-04-03Sell2,50012,540$27.7969.5-4.2812,540 (Direct)
Cole G BradleyCOO2013-03-06Sell2,50012,540$28.5771.4-6.912,540 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-21Buy49,08512,211,834$27.781363.6-4.25
1,614,513 (See Footnote)
10,306,239 (See Footnotes(F7,F14,F15))
277,189 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
HIBBS KATHY LSVP & General Counsel2013-02-20Sell2,7167,087$28.1376.4-5.447,087 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-14Buy52,00012,162,749$28.481481-6.6
1,609,152 (See Footnote)
10,263,580 (See Footnotes(F7,F14,F15))
276,124 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
MYERS WOODROW A JRDirector2013-02-14Sell41,2502,891$28.41171.5-6.342,891 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-11Buy116,36012,110,749$28.153275.5-5.51
1,603,265 (See Footnote)
10,218,600 (See Footnotes(F7,F14,F15))
274,991 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-02-06Sell2,50014,085$28.0370.1-5.114,085 (Direct)
LIVINGSTON RANDALL SDirector2013-01-28Sell2,0006,149$28.7757.5-7.546,149 (Direct)
Schorno Dean LCFO2013-01-09Sell2,62523,504$2873.5-517,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-01-09Sell2,50014,085$27.8869.7-4.5914,085 (Direct)
Shak StevenEVP of R&D & CMO2012-12-18Sell5,000333,768$27.74138.7-4.11333,768 (Direct)
Popovits Kimberly JPresident and CEO2012-12-13Sell5,0000$27.79139-4.28Link
Schorno Dean LCFO2012-12-11Sell3,00023,504$2884-517,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2012-11-26Sell2,0006,149$27.8455.7-4.456,149 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-21Buy229,30012,263,857$26.836152.1-0.86288 (Direct)
271,800 (See Footnote)
1,589,551 (See Footnotes(F5,F14,F15))
10,117,174 (See Footnotes(F7,F14,F15))
271,806 (See Footnotes(F9,F14,F15))
13,238 (See Footnote(F9,F14,F15))
COLELLA SAMUEL DDirector2012-11-20Sell30,61636,437$26.89823.3-1.0836,437 (Direct)
0 (Versant Venture Capital I, L.P.)
0 (Versant Side Fund I, L.P.)
0 (Versant Affiliates Fund I-A, L.P.)
0 (Versant Affiliates Fund I-B, L.P.)
Shak StevenEVP of R&D & CMO2012-11-20Sell5,000338,768$26.94134.7-1.26338,768 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-14Buy103,16713,526$27.322818.5-2.64288 (Direct)
13,238 (See Footnote)
Popovits Kimberly JPresident and CEO2012-11-14Sell5,0000$27.24136.2-2.35Link
BAKER FELIXDirector, 10% Owner2012-11-13Buy823,77213,526$27.8122909.1-4.35288 (Direct)
13,238 (See Footnote)
Schorno Dean LCFO2012-11-12Sell3,00023,504$2884-517,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-11-08Sell2,50014,085$28.6271.6-7.0614,085 (Direct)
Popovits Kimberly JPresident and CEO2012-10-16Sell10,0000$33.08330.8-19.59Link
Shak StevenEVP of R&D & CMO2012-10-16Sell5,000343,768$35.25176.3-24.54343,768 (Direct)
Schorno Dean LCFO2012-10-12Sell3,00023,504$33.79101.4-21.2817,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
HIBBS KATHY LSVP & General Counsel2012-10-11Sell1,25011,367$33.7842.2-21.2611,367 (Direct)
Cole G BradleyCOO2012-10-09Sell2,50014,085$34.887-23.5614,085 (Direct)
Shak StevenEVP of R&D & CMO2012-09-18Sell5,000348,768$33.76168.8-21.21348,768 (Direct)
Popovits Kimberly JPresident and CEO2012-09-13Sell5,0000$31.69158.5-16.06Link
Cole G BradleyCOO2012-09-06Sell2,50014,085$35.0187.5-24.0214,085 (Direct)
MYERS WOODROW A JRDirector2012-08-21Sell16,5002,236$35.2580.8-24.432,236 (Direct)
Shak StevenEVP of R&D & CMO2012-08-20Sell5,000353,768$34.99175-23.98353,768 (Direct)
Popovits Kimberly JPresident and CEO2012-08-13Sell10,0000$34.72347.2-23.39Link
Cole G BradleyCOO2012-08-08Sell2,50014,085$30.4976.2-12.7614,085 (Direct)
LIVINGSTON RANDALL SDirector2012-07-26Sell2,0006,149$35.971.8-25.916,149 (Direct)
Shak StevenChief Medical Officer2012-07-24Sell5,000358,768$34.24171.2-22.31358,768 (Direct)
Popovits Kimberly JPresident and CEO2012-07-13Sell7,1000$34.76246.8-23.48Link
Scott Randal WCEO, InVitae Corporation*2012-07-11Sell30,0000$35.391061.7-24.84Link
Cole G BradleyCOO2012-07-05Sell2,50014,085$35.9589.9-26.0114,085 (Direct)
Shak StevenChief Medical Officer2012-06-25Sell5,000363,768$33.25166.3-20363,768 (Direct)
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-20.26Link
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-20.26Link
Scott Randal WCEO, InVitae Corporation*2012-06-12Sell30,0000$33.541006.2-20.69Link
Cole G BradleyCOO2012-06-06Sell2,50013,507$33.9784.9-21.713,507 (Direct)
Shak StevenChief Medical Officer2012-05-24Sell5,000367,849$33.8169-21.3367,849 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-22Buy167,4061,488,539$32.265400.5-17.54
1,488,539 (See Footnote)
COLELLA SAMUEL DDirector2012-05-18Sell26,294664,113$33.03868.5-19.4726,891 (Direct)
582,174 (Versant Venture Capital I, L.P.)
11,210 (Versant Side Fund I, L.P.)
13,222 (Colella Family Partners, L.P.)
10,414 (Versant Affiliates Fund I-A, L.P.)
20,202 (Versant Affiliates Fund I-B, L.P.)
BAKER JULIANDirector, 10% Owner2012-05-16Buy376,0591,488,539$33.8812740.9-21.49
1,488,539 (See Footnote)
Popovits Kimberly JPresident and CEO2012-05-16Sell10,0000$34.23342.3-22.29Link
Schorno Dean LCFO2012-05-15Sell1,00023,504$33.6933.7-21.0417,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER JULIANDirector, 10% Owner2012-05-11Buy114,8881,488,539$29.963442-11.21
1,488,539 (See Footnote)
Scott Randal WCEO, InVitae Corporation*2012-05-11Sell30,0000$30.22906.6-11.98Link
Cole G BradleyCOO2012-05-09Sell2,50013,507$28.8772.2-7.8613,507 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-08Buy195,70113,238$28.455567.7-6.5
13,238 (See Footnote)
LIVINGSTON RANDALL SDirector2012-04-26Sell2,0006,149$28.2156.4-5.716,149 (Direct)
Shak StevenChief Medical Officer2012-04-24Sell5,000372,849$27.93139.7-4.76372,849 (Direct)
Popovits Kimberly JPresident and CEO2012-04-23Sell5,0000$27.79139-4.28Link
Schorno Dean LCFO2012-04-16Sell1,00024,504$27.9828-4.9318,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation*2012-04-11Sell20,0000$28.59571.8-6.96Link
Cole G BradleyCOO2012-04-04Sell2,50013,507$30.2875.7-12.1513,507 (Direct)
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.4-11.57377,849 (Direct)
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.4-11.54Link
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.4-11.54Link
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.4-11.57377,849 (Direct)
Schorno Dean LCFO2012-03-15Sell1,00025,504$31.0831.1-14.4119,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation2012-03-13Sell30,0000$31.05931.5-14.33Link
Cole G BradleyCOO2012-03-08Sell2,50013,507$29.9474.9-11.1613,507 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-08Buy4,5081,484,977$30.11135.7-11.66
1,484,977 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-08Buy1,099227,840$30.1133.1-11.66
227,840 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-08Buy41,5848,255,421$30.111252.1-11.66
8,255,421 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-05Buy261,7618,213,837$29.817803.1-10.77
8,213,837 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-05Buy6,923226,741$29.81206.4-10.77
226,741 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-05Buy31,3321,480,469$29.81934-10.77
1,480,469 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-29Buy6,476219,818$29.06188.2-8.47
219,818 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-29Buy245,0317,952,076$29.067120.6-8.47
7,952,076 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-29Buy29,7561,449,137$29.06864.7-8.47
1,449,137 (Through Partnership)
Popovits Kimberly JPresident and CEO2012-02-24Sell10,0000$28.5285-6.67Link
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-23Buy114,5187,707,045$28.063213.4-5.2
7,707,045 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-23Buy3,022213,342$28.0684.8-5.2
213,342 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-23Buy13,3321,419,381$28.06374.1-5.2
1,419,381 (Through Partnership)
Shak StevenChief Medical Officer2012-02-23Sell5,000382,849$28.14140.7-5.47382,849 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-16Buy33,1851,406,049$29.34973.6-9.34
1,406,049 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-16Buy7,213210,320$29.37211.8-9.43
210,320 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-16Buy272,9097,592,527$29.378015.3-9.43
7,592,527 (Through Partnership)
Schorno Dean LCFO2012-02-15Sell75526,749$28.7621.7-7.5120,600 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2012-02-15Sell1,00026,504$28.7628.8-7.5120,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-10Buy417,9157,319,618$26.3611016.20.91
7,319,618 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-10Buy11,043203,107$26.36291.10.91
203,107 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-10Buy66,5831,372,864$26.361755.10.91
1,372,864 (Through Partnership)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.61.6Link
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.61.6Link
Cole G BradleyCOO2012-02-08Sell2,50014,450$26.4766.20.4914,450 (Direct)
LIVINGSTON RANDALL SDirector2012-01-26Sell2,0006,149$27.5155-3.316,149 (Direct)
Popovits Kimberly JPresident and CEO2012-01-25Sell5,0000$26.42132.10.68Link
Popovits Kimberly JPresident and CEO2012-01-24Sell5,0000$26.62133.1-0.08Link
Shak StevenChief Medical Officer2012-01-24Sell5,000382,778$26.74133.7-0.52382,778 (Direct)
Schorno Dean LCFO2012-01-17Sell1,00024,049$2828-517,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-01-12Sell2,5007,750$27.5468.9-3.417,750 (Direct)
Scott Randal WExecutive Chairman2012-01-11Sell20,0000$27.46549.2-3.13Link
Shak StevenChief Medical Officer2011-12-22Sell5,000387,778$26.03130.22.19387,778 (Direct)
Scott Randal WExecutive Chairman2011-12-13Sell20,0000$27.29545.8-2.53Link
Cole G BradleyCOO2011-12-06Sell2,5007,750$28.5971.5-6.967,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-12-05Buy3,152192,064$28.1288.6-5.41
192,064 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-12-05Buy45,9771,306,281$27.661271.7-3.83
1,306,281 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-12-05Buy117,7516,901,703$28.123311.2-5.41
6,901,703 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-23Buy5,5311,260,304$25.91143.32.66
1,260,304 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-23Buy5,750188,912$25.94149.22.54
188,912 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-23Buy193,7396,783,952$25.915019.82.66
6,783,952 (Through Partnership)
Shak StevenChief Medical Officer2011-11-22Sell5,000392,778$26.07130.42.03392,778 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-16Buy64,5976,590,213$27.711790-4.01
6,590,213 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-16Buy2,550183,162$27.7170.7-4.01
183,162 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-16Buy4581,254,773$27.3512.5-2.74
1,254,773 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-14Buy10,106180,612$27.23275.2-2.31
180,612 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-14Buy249,3756,525,616$27.236790.5-2.31
6,525,616 (Through Partnership)
Scott Randal WExecutive Chairman2011-11-11Sell20,0000$27.24544.8-2.35Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-09Buy5421,254,315$26.7914.5-0.71
1,254,315 (Through Partnership)
Cole G BradleyCOO2011-11-08Sell2,5007,750$26.666.507,750 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-07Buy209,5126,276,241$25.945434.72.54
6,276,241 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-07Buy8,847170,506$25.94229.52.54
170,506 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-03Buy1201,253,773$24.482.98.66
1,253,773 (Through Partnership)
LIVINGSTON RANDALL SDirector2011-10-27Sell2,0006,149$22.0844.220.476,149 (Direct)
Shak StevenChief Medical Officer2011-10-24Sell5,000392,778$21.76108.822.24392,778 (Direct)
Scott Randal WExecutive Chairman2011-10-11Sell20,0000$22.83456.616.51Link
Cole G BradleyCOO2011-10-06Sell5,0007,750$22.31111.619.237,750 (Direct)
Scott Randal WExecutive Chairman2011-09-13Sell20,0000$20.81416.227.82Link
Cole G BradleyCOO2011-09-06Sell2,5007,750$22.0855.220.477,750 (Direct)
Shak StevenChief Medical Officer2011-08-24Sell5,000392,778$23.02115.115.55392,778 (Direct)
Scott Randal WExecutive Chairman2011-08-11Sell20,0000$24.44488.88.84Link
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.25.37,750 (Direct)
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.25.37,750 (Direct)
LIVINGSTON RANDALL SDirector2011-07-27Sell2,0006,149$26.4552.90.576,149 (Direct)
Shak StevenChief Medical Officer2011-07-25Sell5,000392,778$27.61138.1-3.66392,778 (Direct)
Scott Randal WExecutive Chairman2011-07-12Sell20,0001,503,444$27.36547.2-2.781,491,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Cole G BradleyCOO2011-07-06Sell5,0007,750$27.74138.7-4.117,750 (Direct)
Shak StevenChief Medical Officer2011-06-23Sell5,000392,778$27.12135.6-1.92392,778 (Direct)
Schorno Dean LCFO2011-06-15Sell1,00025,049$25.9125.92.6618,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-06-13Sell20,0001,523,444$25.69513.83.541,511,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-09Buy119194,415$26.193.11.57
194,415 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-06-09Buy4,388161,659$26.19114.91.57
161,659 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-09Buy203,6526,059,449$26.25335.71.53
6,059,449 (Through Partnership)
Cole G BradleyCOO2011-06-06Sell2,5007,750$26.1865.51.67,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-06-01Buy4,631157,271$27.34126.6-2.71
157,271 (Through Partnership)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-01Buy112194,296$27.353.1-2.74
194,296 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-01Buy181,6935,855,797$27.354969.3-2.74
5,855,797 (Through Partnership)
Shak StevenChief Medical Officer2011-05-25Sell5,000392,778$25.55127.84.11392,778 (Direct)
Schorno Dean LCFO2011-05-12Sell1,00026,049$26.4826.50.4519,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-05-11Sell20,0000$26.66533.2-0.23Link
Cole G BradleyCOO2011-05-09Sell2,5007,750$25.9364.82.587,750 (Direct)
LIVINGSTON RANDALL SDirector2011-04-27Sell2,0000$26.0452.12.15Link
Shak StevenChief Medical Officer2011-04-25Sell5,0000$25.38126.94.81Link
Popovits Kimberly JPresident and CEO2011-04-15Sell8,0000$25.49203.94.35Link
Schorno Dean LCFO2011-04-14Sell1,0000$25.3225.35.06Link
Scott Randal WExecutive Chairman2011-04-12Sell20,0000$25.96519.22.47Link
Cole G BradleyCOO2011-04-06Sell5,0000$26.91134.6-1.15Link
Shak StevenChief Medical Officer2011-03-24Sell5,0000$24.45122.38.79Link
Schorno Dean LCFO2011-03-15Sell1,0000$23.7923.811.81Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.39.51Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.39.51Link
Scott Randal WExecutive Chairman2011-03-11Sell20,0000$25.62512.43.83Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-10Buy70,8560$26.031844.42.19Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-08Buy9,6480$25.06241.86.15Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-08Buy349,5660$25.068760.16.15Link
Cole G BradleyCOO2011-03-08Sell2,5000$25.2363.15.43Link
COLELLA SAMUEL DDirector2011-03-03Sell34,3200$25.45873.44.52Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-02Buy160,3370$25.694119.13.54Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-02Buy4,4260$25.69113.73.54Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-02-25Buy158,3550$23.393703.913.72Link
14159 capital (GP), LLCDirector, 10% Owner2011-02-25Buy4,3700$23.39102.213.72Link
Shak StevenChief Medical Officer2011-02-24Sell5,0000$23.27116.414.31Link
Schorno Dean LCFO2011-02-15Sell1,0000$22.5122.518.17Link
Popovits Kimberly JPresident and CEO2011-02-15Sell8,0000$22.51180.118.17Link
Scott Randal WExecutive Chairman2011-02-11Sell20,0000$22.244419.82Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,000309,424$21.15169.225.77Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,0000$21.15169.225.77Link
Schorno Dean LCFO2011-01-13Sell1,27626,149$21.0626.926.31Link
Scott Randal WExecutive Chairman2011-01-11Sell20,0001,642,410$21.73434.622.41Link
Cole G BradleyCOO2011-01-06Sell5,0001,000$22.13110.720.2Link
Popovits Kimberly JPresident and CEO2010-12-16Sell8,000310,624$22.71181.717.13Link
Scott Randal WExecutive Chairman2010-12-13Sell20,0001,696,410$22.46449.218.43Link
Cole G BradleyCOO & CFO2010-12-13Sell2,5001,000$22.6456.617.49Link
Popovits Kimberly JPresident and CEO2010-11-16Sell8,000310,624$17.514052Link
Cole G BradleyCOO & CFO2010-11-11Sell2,5001,000$18.0445.147.45Link
Scott Randal WExecutive Chairman2010-11-11Sell20,0001,666,410$18.27365.445.59Link
Scott Randal WExecutive Chairman2010-10-12Sell20,0001,686,410$13.9527990.68Link
Popovits Kimberly JPresident and CEO2010-09-15Sell7,734310,624$15.1116.876.16Link
Scott Randal WExecutive Chairman2010-09-13Sell20,0001,706,410$14.87297.478.88Link
Cole G BradleyCOO & CFO2010-09-13Sell2,5001,000$15.0137.577.22Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-09Buy145134,196$14.812.179.61Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-09Buy5,2614,934,990$14.8177.979.61Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-02Buy65,4664,929,729$14.46946.683.96Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-02Buy1,807134,051$14.4626.183.96Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-30Buy3,415132,244$14.3749.185.11Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-30Buy123,7114,864,263$14.371777.785.11Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-23Buy150,4694,740,552$14.522184.883.2Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-23Buy4,153128,829$14.5260.383.2Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-18Buy530124,676$14.997.977.45Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-18Buy19,1874,590,083$14.99287.677.45Link
Popovits Kimberly JPresident and CEO2010-08-17Sell8,000288,116$15.07120.676.51Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-13Buy2,924124,146$14.8543.479.12Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-13Buy105,9104,570,896$14.851572.879.12Link
Cole G BradleyCOO & CFO2010-08-12Sell2,5001,000$1537.577.33Link
Scott Randal WExecutive Chairman2010-08-11Sell20,0001,726,410$14.71294.280.83Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-10Buy164,2424,464,986$14.612399.682.07Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-10Buy4,533121,222$14.6166.282.07Link
Baker JoffreChief Scientific Officer2010-08-09Sell4,629163,088$14.7568.380.34Link
Scott Randal WExecutive Chairman2010-07-13Sell20,0001,746,410$12.81256.2107.65Link
Baker JoffreChief Scientific Officer2010-07-07Sell4,629167,717$13.0560.4103.83Link
Scott Randal WExecutive Chairman2010-06-11Sell20,0001,766,410$14.1528387.99Link
Baker JoffreChief Scientific Officer2010-06-10Sell4,629172,346$14.056589.32Link
Popovits Kimberly JPresident and CEO2010-05-17Sell8,000310,624$15.78126.268.57Link
Cole G BradleyCOO & CFO2010-05-12Sell2,5001,000$15.8739.767.61Link
Scott Randal WExecutive Chairman2010-05-11Sell20,0001,776,410$15.61312.270.4Link
Baker JoffreChief Scientific Officer2010-05-10Sell4,629176,975$15.5171.871.5Link
Scott Randal WExecutive Chairman2010-04-13Sell20,0001,796,410$16.87337.457.68Link
Cole G BradleyCOO & CFO2010-04-12Sell5,0001,000$16.984.557.4Link
Baker JoffreChief Scientific Officer2010-04-12Sell4,629181,604$16.8878.157.58Link
Popovits Kimberly JPresident and CEO2010-03-16Sell20,000288,116$19.4538936.76Link
Scott Randal WExecutive Chairman2010-03-11Sell20,0001,800,646$19.338637.82Link
Cole G BradleyCOO & CFO2010-03-11Sell2,5001,000$19.3948.537.18Link
COLELLA SAMUEL DDirector2010-03-10Sell106,70085,050$19.452075.336.76Link
Baker JoffreChief Scientific Officer2010-03-08Sell4,629150,120$19.8391.834.14Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-19Buy3,645116,689$17.0562.156.01Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-19Buy132,0704,300,744$17.052251.856.01Link
Scott Randal WExecutive Chairman2010-02-11Sell20,0001,830,646$17.23344.654.38Link
Cole G BradleyCOO & CFO2010-02-11Sell2,5001,000$17.5143.851.91Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-10Buy9,437113,044$17.01160.556.38Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-10Buy341,8544,168,674$17.015814.956.38Link
Baker JoffreChief Scientific Officer2010-02-09Sell4,629145,491$17.1479.355.19Link
Cole G BradleyCOO & CFO2010-01-12Sell5,0001,000$17.2586.354.2Link
Baker JoffreChief Scientific Officer2010-01-11Sell4,629150,120$17.4780.952.26Link
Shak StevenChief Medical Officer2009-12-21Sell5,000388,278$20.12100.632.21Link
Popovits Kimberly JPresident and CEO2009-12-15Sell5,000313,506$20.3910230.46Link
Cole G BradleyCOO & CFO2009-12-14Sell2,0001,000$20.4240.830.26Link
Scott Randal WExecutive Chairman2009-12-11Sell12,0001,880,646$20.24242.931.42Link
Baker JoffreChief Scientific Officer2009-12-08Sell4,629154,749$20.2693.831.29Link
Popovits Kimberly JPresident and CEO2009-11-17Sell20,000318,506$19.21384.238.47Link
Cole G BradleyCOO & CFO2009-11-12Sell6653,000$20.0413.332.73Link
Scott Randal WExecutive Chairman2009-11-11Sell12,0001,892,646$19.99239.933.07Link
Baker JoffreChief Scientific Officer2009-11-10Sell4,629159,378$2092.633Link
Shak StevenChief Medical Officer2009-10-20Sell5,000393,278$20.65103.328.81Link
Popovits Kimberly JPresident and CEO2009-10-15Sell5,000338,506$20.42102.130.26Link
Scott Randal WExecutive Chairman2009-10-13Sell12,0001,904,646$20.66247.928.75Link
Baker JoffreChief Scientific Officer2009-10-07Sell4,629164,007$21.179825.65Link
Shak StevenChief Medical Officer2009-09-22Sell5,000398,278$21.13105.725.89Link
Popovits Kimberly JPresident and CEO2009-09-15Sell5,000343,506$20.73103.728.32Link
Scott Randal WExecutive Chairman2009-09-11Sell12,0001,916,646$20.6724828.69Link
Baker JoffreChief Scientific Officer2009-09-04Sell4,629168,636$20.1293.132.21Link
Shak StevenChief Medical Officer2009-08-25Sell5,000403,278$20.77103.928.07Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-17Buy1,839103,607$19.9836.733.13Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-17Buy66,6303,826,820$19.981331.333.13Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-17Buy34194,184$19.980.733.13Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-17Buy11,6571,253,653$19.98232.933.13Link
Popovits Kimberly JPresident and CEO2009-08-17Sell5,000348,506$19.5397.736.2Link
Cole G BradleyCOO & CFO2009-08-13Sell5,0003,000$2010033Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-12Buy15,8771,241,996$19.49309.436.48Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-12Buy45194,150$19.50.936.41Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-12Buy90,7543,760,190$19.491768.836.48Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-12Buy2,508101,768$19.4948.936.48Link
Scott Randal WExecutive Chairman2009-08-11Sell12,0001,928,646$19.4223336.97Link
Baker JoffreChief Scientific Officer2009-08-10Sell4,629173,265$19.4890.236.55Link
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.166.15
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.166.15
Scott Randal WExecutive Chairman2009-06-11Sell6,0001,940,646$18.27109.645.59
Baker JoffreChief Scientific Officer2009-06-08Sell4,629182,523$17.6981.950.37
Shak StevenChief Medical Officer2009-05-26Sell5,000408,278$199540
14159 capital (GP), LLCDirector, 10% Owner2009-05-21Buy1,10899,260$17.9719.948.02
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-21Buy90194,161$17.971.648.02
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-21Buy39,7783,669,436$17.97714.848.02
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-21Buy25194,105$17.970.448.02
Popovits Kimberly JPresident and CEO2009-05-15Sell5,000353,506$20.12100.632.21
Scott Randal WExecutive Chairman2009-05-12Sell12,0001,946,646$19.46233.536.69
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-11Buy88194,080$19.551.736.06
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-11Buy312194,071$19.556.136.06
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-11Buy137,4663,629,658$19.552687.536.06
14159 capital (GP), LLCDirector, 10% Owner2009-05-11Buy3,82798,152$19.5574.836.06
Baker JoffreChief Scientific Officer2009-05-08Sell4,629187,152$19.7291.334.89
Scott Randal WExecutive Chairman2009-04-14Sell12,0001,958,646$25.47305.64.44
Baker JoffreChief Scientific Officer2009-04-01Sell4,629191,781$25.271175.26
Scott Randal WExecutive Chairman2009-03-11Sell12,0001,970,646$19.4232.837.11
Baker JoffreChief Scientific Officer2009-03-03Sell4,629196,410$19.1388.639.05
Cole G BradleyCOO & CFO2009-02-17Sell5,0003,000$21.52107.623.61
Baker JoffreChief Scientific Officer2009-02-12Sell4,62922,226$20.695.429.13
Baker JoffreChief Scientific Officer2009-02-12Sell4,629201,039$20.695.429.13
Scott Randal WExecutive Chairman, Director2009-02-11Sell12,0001,982,646$20.85250.227.58
Baker JoffreChief Scientific Officer2009-01-12Sell4,62926,855$19.4189.837.04
Shak StevenChief Medical Officer2008-12-22Sell100413,278$20.17231.88
Baker JoffreChief Scientific Officer2008-12-10Sell4,62931,484$19.2589.138.18
Baker JoffreChief Scientific Officer2008-12-10Sell4,629205,668$19.2589.138.18
Scott Randal WCEO, Director2008-12-09Sell12,0001,955,298$18.4220.844.57
Baker JoffreChief Scientific Officer2008-11-12Sell4,62936,113$19.879233.87
Baker JoffreChief Scientific Officer2008-11-12Sell4,629210,297$19.879233.87
Scott Randal WCEO, Director2008-11-11Sell12,0001,967,298$20.05240.632.67
Cole G BradleyEVP & CFO2008-11-10Sell10,0004,000$20.17201.731.88
Scott Randal WCEO, Director2008-10-14Sell12,0001,979,298$20.36244.330.65
Baker JoffreChief Scientific Officer2008-10-01Sell9,25840,742$22.51208.418.17
Shak StevenChief Medical Officer2008-09-24Sell5,000413,378$22.67113.417.34
Scott Randal WCEO, Director2008-09-16Sell12,0001,991,298$21.79261.522.07
Shak StevenChief Medical Officer2008-08-26Sell5,000418,378$22.93114.716.01
Baker JoffreChief Scientific Officer2008-08-26Sell4,629214,926$22.6910517.23
Cole G BradleyEVP & CFO2008-08-18Sell9,2984,000$23.67220.112.38
Popovits Kimberly JPresident and COO2008-08-15Sell25,000358,506$24.246069.74
Scott Randal WCEO, Director2008-08-12Sell12,0002,003,298$23.76285.111.95
Scott Randal WCEO, Director2008-07-15Sell12,0002,015,298$2125226.67
Baker JoffreChief Scientific Officer2008-07-01Sell4,629219,555$19.2689.238.11
Shak StevenChief Medical Officer2008-06-24Sell100423,378$20233
Scott Randal WCEO, Director2008-06-10Sell12,0002,027,298$19.9223933.53
Baker Brothers Life Sciences CDirector, 10% Owner2008-06-09Buy320,9833,492,192$19.916390.833.6
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-06-09Buy76,0151,226,119$19.911513.533.6
14159 capital (GP), LLCDirector, 10% Owner2008-06-09Buy10,29994,325$19.91205.133.6
Baker JoffreChief Scientific Officer2008-06-02Sell4,629228,813$17.9983.347.86
Scott Randal WCEO, Director2008-05-13Sell12,0002,039,298$18.7522541.87
Baker JoffreChief Scientific Officer2008-05-08Sell4,629233,442$19.2789.238.04
Scott Randal WCEO, Director2008-04-15Sell12,0002,051,298$17.22206.654.47
Scott Randal WCEO, Director2008-03-11Sell12,0002,063,298$18.84226.141.19
Baker JoffreChief Scientific Officer2008-03-05Sell4,629242,700$20.4894.829.88
Shak StevenChief Medical Officer2008-02-26Sell5,000423,478$20.23101.231.49
Cole G BradleyEVP & CFO2008-02-19Sell9,0008,298$22.58203.217.8
Scott Randal WCEO, Director2008-02-12Sell12,0002,075,298$23.01276.115.6
Baker JoffreChief Scientific Officer2008-02-11Sell4,629247,329$22.94106.215.95
Scott Randal WCEO, Director2008-01-15Sell12,0002,087,298$25.54306.54.15
Baker JoffreChief Scientific Officer2008-01-02Sell4,629251,958$22.66104.917.39
Baker JoffreChief Scientific Officer2007-12-03Sell4,6290$23.1106.915.15
Popovits Kimberly JPresident and COO2007-11-27Sell6,655383,506$22146.420.91
Scott Randal WCEO, Director2007-11-09Sell12,0002,111,299$23.07276.815.3
Baker JoffreChief Scientific Officer2007-11-08Sell4,629265,845$23.21107.414.61
Scott Randal WCEO2007-10-09Sell12,0002,123,299$20.16241.931.94
Baker JoffreChief Scientific Officer2007-10-01Sell4,629270,474$19.8491.834.07
Scott Randal WCEO2007-09-11Sell12,0002,135,299$19.69236.335.09
Scott Randal WCEO, Director2007-09-11Sell12,0002,135,299$19.7236.435.03
Baker JoffreChief Scientific Officer2007-09-10Sell4,629275,103$19.5790.635.92
Goldberg Michael DDirector2007-08-23Buy5,3505,350$18.76100.441.79
Scott Randal WCEO2007-08-15Sell12,0002,147,299$19.91238.933.6
Baker JoffreChief Scientific Officer2007-08-08Sell4,629279,732$19.449036.83
Scott Randal WCEO2007-07-18Sell12,0002,159,299$21.18254.225.59
Baker JoffreChief Scientific Officer2007-07-02Sell4,629284,361$19.018839.93
Scott Randal WCEO2007-06-19Sell12,0002,171,299$19.16229.938.83
Baker JoffreChief Scientific Officer2007-06-01Sell4,629288,990$17.5681.351.48
Baker Bros. Capital (GP), LLCDirector2007-05-30Buy545193,992$16.328.962.99
Baker Biotech Capital (GP), LLDirector2007-05-30Buy81,1811,150,104$16.321324.962.99
Baker Brothers Life Sciences CDirector2007-05-30Buy214,0993,171,209$16.323494.162.99
14159 capital (GP), LLCDirector2007-05-30Buy6,80784,026$16.32111.162.99
14159 capital (GP), LLCDirector2007-05-24Buy16,26177,219$16.59269.860.34
Baker Brothers Life Sciences CDirector2007-05-24Buy511,5532,957,110$16.598486.760.34
Baker Biotech Capital (GP), LLDirector2007-05-24Buy193,9661,068,923$16.593217.960.34
Baker Bros. Capital (GP), LLCDirector2007-05-24Buy1,303193,447$16.5921.660.34
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.971.61
14159 capital (GP), LLCDirector2007-05-21Buy22,49160,958$15.5348.671.61
14159 capital (GP), LLCDirector2007-05-21Buy160,958$15.5071.61
Baker Brothers Life Sciences CDirector2007-05-21Buy707,4582,445,557$15.510965.671.61
Baker Biotech Capital (GP), LLDirector2007-05-21Buy268,248874,957$15.54157.871.61
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.971.61
Scott Randal WCEO2007-05-08Sell12,0002,183,299$16.62199.460.05
Baker JoffreChief Scientific Officer2007-05-08Sell4,629293,619$16.3175.563.09
Scott Randal WCEO2007-04-10Sell12,0002,195,299$17.27207.254.02
Baker JoffreChief Scientific Officer2007-04-02Sell4,629298,248$17.1679.455.01
Baker / Tisch Capital (GP), LLDirector2007-03-09Buy3,181193,759$18.2858.145.51
Baker Bros. Capital (GP), LLCDirector2007-03-09Buy376190,341$18.286.945.51
Baker Biotech Capital (GP), LLDirector2007-03-09Buy62,325606,709$18.281139.345.51
Baker Brothers Life Sciences CDirector2007-03-09Buy168,5601,738,099$18.283081.345.51
14159 capital (GP), LLCDirector2007-03-09Buy5,37538,467$18.2898.345.51
Scott Randal WCEO2007-03-06Sell12,0002,207,299$18.35220.244.96
Baker Bros. Capital (GP), LLCDirector2007-03-02Buy119189,965$18.092.247.04
14159 capital (GP), LLCDirector2007-03-02Buy1,70733,092$18.0930.947.04
Baker / Tisch Capital (GP), LLDirector2007-03-02Buy1,072190,578$18.119.446.96
Baker Biotech Capital (GP), LLDirector2007-03-02Buy19,795544,384$18.09358.147.04
Baker Brothers Life Sciences CDirector2007-03-02Buy53,5331,569,539$18.09968.447.04
Baker JoffreChief Scientific Officer2007-03-01Sell4,629302,877$18.1884.246.31
MYERS WOODROW A JRDirector2007-02-21Buy2,00012,000$19.6339.335.51
Baker Brothers Life Sciences CDirector2007-02-16Buy25,4121,516,006$18.54471.143.47
Baker Biotech Capital (GP), LLDirector2007-02-16Buy9,396524,589$18.54174.243.47
Baker / Tisch Capital (GP), LLDirector2007-02-16Buy525189,506$18.549.743.47
14159 capital (GP), LLCDirector2007-02-16Buy81131,385$18.541543.47
Baker Bros. Capital (GP), LLCDirector2007-02-16Buy56189,846$18.54143.47
Baker Bros. Capital (GP), LLCDirector2007-02-14Buy579189,790$18.2510.645.75
Baker / Tisch Capital (GP), LLDirector2007-02-14Buy5,346188,981$18.2597.645.75
Baker Biotech Capital (GP), LLDirector2007-02-14Buy95,783515,193$18.25174845.75
14159 capital (GP), LLCDirector2007-02-14Buy8,25630,574$18.25150.745.75
Baker Brothers Life Sciences CDirector2007-02-14Buy259,0441,490,594$18.254727.645.75
Scott Randal WCEO2007-02-13Sell12,0002,219,299$18.12217.446.8
Baker JoffreChief Scientific Officer2007-02-08Sell4,629307,506$18.9787.840.22
Baker / Tisch Capital (GP), LLDirector2006-12-06Buy642183,635$21.5813.923.26
Baker Brothers Life Sciences CDirector2006-12-06Buy34,1731,231,550$21.58737.523.26
14159 capital (GP), LLCDirector2006-12-06Buy1,12022,318$21.5824.223.26
Baker Biotech Capital (GP), LLDirector2006-12-06Buy12,237419,410$21.58264.123.26
MYERS WOODROW A JRDirector2006-12-05Buy10,00010,000$21.97219.721.07
Baker / Tisch Capital (GP), LLDirector2006-12-05Buy9,096182,993$20.6187.429.13
Baker Biotech Capital (GP), LLDirector2006-12-05Buy173,441407,173$20.63572.929.13
14159 capital (GP), LLCDirector2006-12-05Buy15,88021,198$20.6327.129.13
Baker Brothers Life Sciences CDirector2006-12-05Buy484,3331,197,377$20.69977.329.13
14159 capital (GP), LLCDirector2006-09-08Buy5,3185,318$14.0574.789.32Link
Baker Biotech Capital (GP), LLDirector2006-09-08Buy75,246233,732$14.051057.289.32Link
Baker Brothers Life Sciences CDirector2006-09-08Buy237,236713,044$14.053333.289.32Link
Baker Biotech Capital III (GP)10% Owner2005-10-04Buy136,316252,529$121635.8121.67Link
Baker Biotech Capital II (GP),10% Owner2005-10-04Buy38,684181,478$12464.2121.67Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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