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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Randal W. Scott,PhDN/A1,185,1173.59%2012-07-10
Steven Shak,M.D.N/A326,3830.99%2016-02-15
Joffre B. Baker,PhDN/A132,8460.4%2012-02-15
Dr. Fred E. Cohen,M.D.,D.Phil.N/A64,5200.2%2016-04-01
Kimberly J. PopovitsN/A58,7960.18%2016-02-15
G. Bradley ColeCOO34,9700.11%2016-02-15
Mr. James J. VaughnChief Commercial Officer31,255less than 0.1%2016-02-15
Mr. Frederic PlaN/A25,618less than 0.1%2016-02-15
Mr. Dean L. SchornoN/A24,524less than 0.1%2014-06-10
Brook H. ByersN/A23,951less than 0.1%2010-12-09

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Vaughn James JChief Commercial Officer2016-02-09Sell324,076$280.1-2.7524,076 (Direct)
LIVINGSTON RANDALL SDirector2016-01-13Sell1,2506,149$32.1440.2-15.286,149 (Direct)
Cole G BradleyCOO2016-01-12Sell4,00027,428$31.69126.8-14.0727,428 (Direct)
Vaughn James JChief Commercial Officer2016-01-07Sell2,00024,076$33.6367.3-19.0324,076 (Direct)
Cole G BradleyCOO2015-12-08Sell4,00027,428$29.26117-6.9427,428 (Direct)
Leber LauraChief Communication Officer2015-12-07Sell4,20012,959$29.33123.2-7.1612,959 (Direct)
Vaughn James JChief Commercial Officer2015-12-07Sell2,00024,076$29.3358.7-7.1624,076 (Direct)
Cole G BradleyCOO2015-11-10Sell4,00030,326$26.03104.14.6130,326 (Direct)
Cole G BradleyCOO2015-09-09Sell9,66430,326$25.352457.4230,326 (Direct)
Cole G BradleyCOO2015-07-07Sell4,00030,326$27.53110.1-1.0930,326 (Direct)
Cole G BradleyCOO2015-06-09Sell4,00030,326$26.241053.7730,326 (Direct)
Cole G BradleyCOO2015-05-12Sell4,00029,658$27.54110.2-1.1329,658 (Direct)
Popovits Kimberly JPresident and CEO
(Click for the stocks that their CEOs have bought)
2015-04-13Sell3,000203,001$31.2893.8-12.95Link
Cole G BradleyCOO2015-04-07Sell4,00029,658$30.44121.8-10.5529,658 (Direct)
Popovits Kimberly JPresident and CEO2015-03-12Sell3,000204,101$31.9195.7-14.67Link
Cole G BradleyCOO2015-03-10Sell4,00029,658$31.84127.4-14.4829,658 (Direct)
Popovits Kimberly JPresident and CEO2015-02-12Sell3,000204,601$29.8689.6-8.81Link
Cole G BradleyCOO2015-02-10Sell4,00021,645$31.37125.5-13.221,645 (Direct)
LIVINGSTON RANDALL SDirector2015-02-02Sell1,0006,149$31.9331.9-14.726,149 (Direct)
Popovits Kimberly JPresident and CEO2015-01-12Sell3,000204,601$33.46100.4-18.62Link
Popovits Kimberly JPresident and CEO2014-12-11Sell3,000204,601$32.9999-17.46Link
Cole G BradleyCOO2014-12-08Sell4,33621,645$32.52141-16.2721,645 (Direct)
Popovits Kimberly JPresident and CEO2014-11-12Sell4,300205,201$34.82149.7-21.8Link
Cole G BradleyCOO2014-11-10Sell4,00022,891$35.35141.4-22.9722,891 (Direct)
LIVINGSTON RANDALL SDirector2014-11-03Sell3,0006,149$36.24108.7-24.866,149 (Direct)
Popovits Kimberly JPresident and CEO2014-10-13Sell3,000205,201$30.7892.3-11.53Link
Cole G BradleyCOO2014-10-08Sell4,00022,891$28.77115.1-5.3522,891 (Direct)
Popovits Kimberly JPresident and CEO2014-09-11Sell3,000205,201$29.8289.5-8.69Link
Cole G BradleyCOO2014-09-08Sell4,70022,891$30.09141.4-9.522,891 (Direct)
Shak StevenEVP of R&D2014-08-14Sell13,348312,298$27.36365.2-0.48312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-08-12Sell3,000205,201$26.0778.24.45Link
Popovits Kimberly JPresident and CEO2014-07-14Sell3,000205,201$26.5979.82.41Link
Cole G BradleyCOO2014-07-08Sell2,30022,891$27.0562.20.6722,891 (Direct)
Shak StevenEVP of R&D2014-07-01Sell7,000312,298$271890.85312,298 (Direct)
Shak StevenEVP of R&D2014-06-12Sell7,000312,298$26.73187.11.87312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-06-12Sell3,000271,289$26.178.34.33Link
Schorno Dean LCFO2014-06-10Sell4,00030,673$27.62110.5-1.4124,524 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2014-06-09Sell2,33722,891$27.2963.8-0.2222,891 (Direct)
Popovits Kimberly JPresident and CEO2014-05-12Sell3,000270,579$26.5479.62.6Link
Schorno Dean LCFO2014-05-09Sell4,00029,963$25.09100.48.5323,814 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Shak StevenEVP of R&D2014-04-14Sell7,000311,588$26.25183.83.73311,588 (Direct)
Cole G BradleyCOO2014-04-08Sell3,00022,226$27810.8522,226 (Direct)
Shak StevenEVP of R&D2014-03-14Sell7,000311,588$28.36198.5-3.98311,588 (Direct)
Cole G BradleyCOO2014-03-10Sell3,00022,226$27.7683.3-1.9122,226 (Direct)
HIBBS KATHY LSVP & General Counsel2014-02-18Sell1,31215,787$27.8836.6-2.3315,787 (Direct)
Shak StevenEVP of R&D2014-02-14Sell7,000311,588$27.38191.7-0.55311,588 (Direct)
Cole G BradleyCOO2014-02-10Sell3,00024,789$27810.8524,789 (Direct)
Shak StevenEVP of R&D2014-01-15Sell7,000308,283$31.51220.6-13.58308,283 (Direct)
Popovits Kimberly JPresident and CEO2014-01-13Sell2,500261,190$3075-9.23Link
Cole G BradleyCOO2014-01-08Sell3,00018,369$28.1784.5-3.3418,369 (Direct)
Shak StevenEVP of R&D & CMO2013-12-17Sell14,000308,283$29.57414-7.91308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-12-12Sell2,5000$30.6876.7-11.25Link
Schorno Dean LCFO2013-12-09Sell3,00027,706$33.2599.8-18.1121,557 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-12-02Sell1,0006,149$34.9234.9-22.026,149 (Direct)
Popovits Kimberly JPresident and CEO2013-11-13Sell5,0000$34.58172.9-21.26Link
Schorno Dean LCFO2013-11-08Sell3,00027,585$33.36100.1-18.3821,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-11-06Sell2,86818,135$31.3890-13.2218,135 (Direct)
Shak StevenEVP of R&D & CMO2013-10-15Sell5,000308,283$29.67148.4-8.22308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-10-10Sell2,5000$3075-9.23Link
Cole G BradleyCOO2013-10-09Sell2,50018,135$29.9574.9-9.0818,135 (Direct)
Shak StevenEVP of R&D & CMO2013-09-18Sell5,000313,283$33.73168.7-19.27313,283 (Direct)
Popovits Kimberly JPresident and CEO2013-09-12Sell2,5000$34.3185.8-20.64Link
Cole G BradleyCOO2013-09-09Sell2,50018,135$32.5381.3-16.2918,135 (Direct)
Schorno Dean LCFO2013-09-06Sell4,00027,585$32.9131.6-17.2321,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-09-03Sell1,0006,149$31.4931.5-13.536,149 (Direct)
Shak StevenEVP of R&D & CMO2013-08-14Sell5,000318,283$32.98164.9-17.43318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-08-12Sell2,5000$33.0382.6-17.56Link
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-17.8621,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-17.8621,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-08-07Sell2,50019,135$33.6684.2-19.119,135 (Direct)
Shak StevenEVP of R&D & CMO2013-07-23Sell5,000318,283$35.33176.7-22.93318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-07-12Sell5,0000$34.61173.1-21.32Link
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.2-19.4617,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.2-19.4617,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-07-08Sell2,50013,135$33.3383.3-18.313,135 (Direct)
Shak StevenEVP of R&D & CMO2013-06-18Sell5,000323,283$33.52167.6-18.76323,283 (Direct)
Popovits Kimberly JPresident and CEO2013-06-12Sell5,0000$35.68178.4-23.68Link
Schorno Dean LCFO2013-06-10Sell4,00023,985$35.88143.5-24.1117,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER FELIXDirector, 10% Owner2013-06-05Buy381,43213,288,253$36.1613792.6-24.7
1,730,777 (See Footnote)
11,241,654 (See Footnotes(F7,F14,F15))
301,215 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-06-05Sell2,50013,135$36.4791.2-25.3413,135 (Direct)
BAKER FELIXDirector, 10% Owner2013-06-03Buy179,58312,906,821$36.716592.5-25.82
1,690,226 (See Footnote)
10,909,066 (See Footnotes(F7,F14,F15))
292,922 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-06-03Sell1,0006,149$36.436.4-25.196,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-29Buy121,26612,727,238$36.894473.5-26.19
1,671,081 (See Footnote)
10,752,532 (See Footnotes(F7,F14,F15))
289,018 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-05-24Buy79,41714,257,273$36.932932.9-26.27
1,651,301 (See Footnote)
10,646,920 (See Footnotes(F7,F17,F18))
286,384 (See Footnotes(F9,F17,F18))
1,658,061 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-22Sell1,0007,087$37.4837.5-27.357,087 (Direct)
Shak StevenEVP of R&D & CMO2013-05-21Sell5,000327,380$37.19186-26.78327,380 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-16Buy71,43912,526,555$36.452604-25.29
1,649,473 (See Footnote)
10,577,816 (See Footnotes(F7,F14,F15))
284,659 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-05-15Sell1,3376,149$35.8347.9-246,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-14Buy240,42614,093,759$34.348256.2-20.7
1,638,643 (See Footnote)
10,515,769 (See Footnotes(F7,F17,F18))
283,112 (See Footnotes(F9,F17,F18))
1,641,628 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-13Sell1,2507,087$34.4243-20.897,087 (Direct)
Popovits Kimberly JPresident and CEO2013-05-13Sell5,0000$34.7173.5-21.53Link
Schorno Dean LCFO2013-05-09Sell4,00023,241$36.02144.1-24.417,092 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-05-08Sell2,50012,540$35.9990-24.3412,540 (Direct)
Popovits Kimberly JPresident and CEO2013-04-23Sell2,5000$3075-9.23Link
Cole G BradleyCOO2013-04-03Sell2,50012,540$27.7969.5-2.0212,540 (Direct)
Cole G BradleyCOO2013-03-06Sell2,50012,540$28.5771.4-4.6912,540 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-21Buy49,08512,211,834$27.781363.6-1.98
1,614,513 (See Footnote)
10,306,239 (See Footnotes(F7,F14,F15))
277,189 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
HIBBS KATHY LSVP & General Counsel2013-02-20Sell2,7167,087$28.1376.4-3.27,087 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-14Buy52,00012,162,749$28.481481-4.39
1,609,152 (See Footnote)
10,263,580 (See Footnotes(F7,F14,F15))
276,124 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
MYERS WOODROW A JRDirector2013-02-14Sell41,2502,891$28.41171.5-4.122,891 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-11Buy116,36012,110,749$28.153275.5-3.27
1,603,265 (See Footnote)
10,218,600 (See Footnotes(F7,F14,F15))
274,991 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-02-06Sell2,50014,085$28.0370.1-2.8514,085 (Direct)
LIVINGSTON RANDALL SDirector2013-01-28Sell2,0006,149$28.7757.5-5.356,149 (Direct)
Schorno Dean LCFO2013-01-09Sell2,62523,504$2873.5-2.7517,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-01-09Sell2,50014,085$27.8869.7-2.3314,085 (Direct)
Shak StevenEVP of R&D & CMO2012-12-18Sell5,000333,768$27.74138.7-1.84333,768 (Direct)
Popovits Kimberly JPresident and CEO2012-12-13Sell5,0000$27.79139-2.02Link
Schorno Dean LCFO2012-12-11Sell3,00023,504$2884-2.7517,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2012-11-26Sell2,0006,149$27.8455.7-2.196,149 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-21Buy229,30012,263,857$26.836152.11.49288 (Direct)
271,800 (See Footnote)
1,589,551 (See Footnotes(F5,F14,F15))
10,117,174 (See Footnotes(F7,F14,F15))
271,806 (See Footnotes(F9,F14,F15))
13,238 (See Footnote(F9,F14,F15))
COLELLA SAMUEL DDirector2012-11-20Sell30,61636,437$26.89823.31.2636,437 (Direct)
0 (Versant Venture Capital I, L.P.)
0 (Versant Side Fund I, L.P.)
0 (Versant Affiliates Fund I-A, L.P.)
0 (Versant Affiliates Fund I-B, L.P.)
Shak StevenEVP of R&D & CMO2012-11-20Sell5,000338,768$26.94134.71.08338,768 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-14Buy103,16713,526$27.322818.5-0.33288 (Direct)
13,238 (See Footnote)
Popovits Kimberly JPresident and CEO2012-11-14Sell5,0000$27.24136.2-0.04Link
BAKER FELIXDirector, 10% Owner2012-11-13Buy823,77213,526$27.8122909.1-2.09288 (Direct)
13,238 (See Footnote)
Schorno Dean LCFO2012-11-12Sell3,00023,504$2884-2.7517,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-11-08Sell2,50014,085$28.6271.6-4.8614,085 (Direct)
Popovits Kimberly JPresident and CEO2012-10-16Sell10,0000$33.08330.8-17.68Link
Shak StevenEVP of R&D & CMO2012-10-16Sell5,000343,768$35.25176.3-22.75343,768 (Direct)
Schorno Dean LCFO2012-10-12Sell3,00023,504$33.79101.4-19.4117,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
HIBBS KATHY LSVP & General Counsel2012-10-11Sell1,25011,367$33.7842.2-19.3911,367 (Direct)
Cole G BradleyCOO2012-10-09Sell2,50014,085$34.887-21.7514,085 (Direct)
Shak StevenEVP of R&D & CMO2012-09-18Sell5,000348,768$33.76168.8-19.34348,768 (Direct)
Popovits Kimberly JPresident and CEO2012-09-13Sell5,0000$31.69158.5-14.07Link
Cole G BradleyCOO2012-09-06Sell2,50014,085$35.0187.5-22.2214,085 (Direct)
MYERS WOODROW A JRDirector2012-08-21Sell16,5002,236$35.2580.8-22.642,236 (Direct)
Shak StevenEVP of R&D & CMO2012-08-20Sell5,000353,768$34.99175-22.18353,768 (Direct)
Popovits Kimberly JPresident and CEO2012-08-13Sell10,0000$34.72347.2-21.57Link
Cole G BradleyCOO2012-08-08Sell2,50014,085$30.4976.2-10.6914,085 (Direct)
LIVINGSTON RANDALL SDirector2012-07-26Sell2,0006,149$35.971.8-24.156,149 (Direct)
Shak StevenChief Medical Officer2012-07-24Sell5,000358,768$34.24171.2-20.47358,768 (Direct)
Popovits Kimberly JPresident and CEO2012-07-13Sell7,1000$34.76246.8-21.66Link
Scott Randal WCEO, InVitae Corporation*2012-07-11Sell30,0000$35.391061.7-23.06Link
Cole G BradleyCOO2012-07-05Sell2,50014,085$35.9589.9-24.2614,085 (Direct)
Shak StevenChief Medical Officer2012-06-25Sell5,000363,768$33.25166.3-18.11363,768 (Direct)
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-18.38Link
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-18.38Link
Scott Randal WCEO, InVitae Corporation*2012-06-12Sell30,0000$33.541006.2-18.81Link
Cole G BradleyCOO2012-06-06Sell2,50013,507$33.9784.9-19.8413,507 (Direct)
Shak StevenChief Medical Officer2012-05-24Sell5,000367,849$33.8169-19.44367,849 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-22Buy167,4061,488,539$32.265400.5-15.59
1,488,539 (See Footnote)
COLELLA SAMUEL DDirector2012-05-18Sell26,294664,113$33.03868.5-17.5626,891 (Direct)
582,174 (Versant Venture Capital I, L.P.)
11,210 (Versant Side Fund I, L.P.)
13,222 (Colella Family Partners, L.P.)
10,414 (Versant Affiliates Fund I-A, L.P.)
20,202 (Versant Affiliates Fund I-B, L.P.)
BAKER JULIANDirector, 10% Owner2012-05-16Buy376,0591,488,539$33.8812740.9-19.63
1,488,539 (See Footnote)
Popovits Kimberly JPresident and CEO2012-05-16Sell10,0000$34.23342.3-20.45Link
Schorno Dean LCFO2012-05-15Sell1,00023,504$33.6933.7-19.1717,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER JULIANDirector, 10% Owner2012-05-11Buy114,8881,488,539$29.963442-9.11
1,488,539 (See Footnote)
Scott Randal WCEO, InVitae Corporation*2012-05-11Sell30,0000$30.22906.6-9.89Link
Cole G BradleyCOO2012-05-09Sell2,50013,507$28.8772.2-5.6813,507 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-08Buy195,70113,238$28.455567.7-4.29
13,238 (See Footnote)
LIVINGSTON RANDALL SDirector2012-04-26Sell2,0006,149$28.2156.4-3.476,149 (Direct)
Shak StevenChief Medical Officer2012-04-24Sell5,000372,849$27.93139.7-2.51372,849 (Direct)
Popovits Kimberly JPresident and CEO2012-04-23Sell5,0000$27.79139-2.02Link
Schorno Dean LCFO2012-04-16Sell1,00024,504$27.9828-2.6818,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation*2012-04-11Sell20,0000$28.59571.8-4.76Link
Cole G BradleyCOO2012-04-04Sell2,50013,507$30.2875.7-10.0713,507 (Direct)
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.4-9.47377,849 (Direct)
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.4-9.44Link
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.4-9.44Link
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.4-9.47377,849 (Direct)
Schorno Dean LCFO2012-03-15Sell1,00025,504$31.0831.1-12.3919,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation2012-03-13Sell30,0000$31.05931.5-12.3Link
Cole G BradleyCOO2012-03-08Sell2,50013,507$29.9474.9-9.0513,507 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-08Buy4,5081,484,977$30.11135.7-9.56
1,484,977 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-08Buy1,099227,840$30.1133.1-9.56
227,840 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-08Buy41,5848,255,421$30.111252.1-9.56
8,255,421 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-05Buy261,7618,213,837$29.817803.1-8.65
8,213,837 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-05Buy6,923226,741$29.81206.4-8.65
226,741 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-05Buy31,3321,480,469$29.81934-8.65
1,480,469 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-29Buy6,476219,818$29.06188.2-6.3
219,818 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-29Buy245,0317,952,076$29.067120.6-6.3
7,952,076 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-29Buy29,7561,449,137$29.06864.7-6.3
1,449,137 (Through Partnership)
Popovits Kimberly JPresident and CEO2012-02-24Sell10,0000$28.5285-4.46Link
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-23Buy114,5187,707,045$28.063213.4-2.96
7,707,045 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-23Buy3,022213,342$28.0684.8-2.96
213,342 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-23Buy13,3321,419,381$28.06374.1-2.96
1,419,381 (Through Partnership)
Shak StevenChief Medical Officer2012-02-23Sell5,000382,849$28.14140.7-3.23382,849 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-16Buy33,1851,406,049$29.34973.6-7.19
1,406,049 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-16Buy7,213210,320$29.37211.8-7.29
210,320 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-16Buy272,9097,592,527$29.378015.3-7.29
7,592,527 (Through Partnership)
Schorno Dean LCFO2012-02-15Sell75526,749$28.7621.7-5.3220,600 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2012-02-15Sell1,00026,504$28.7628.8-5.3220,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-10Buy417,9157,319,618$26.3611016.23.3
7,319,618 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-10Buy11,043203,107$26.36291.13.3
203,107 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-10Buy66,5831,372,864$26.361755.13.3
1,372,864 (Through Partnership)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.64.01Link
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.64.01Link
Cole G BradleyCOO2012-02-08Sell2,50014,450$26.4766.22.8714,450 (Direct)
LIVINGSTON RANDALL SDirector2012-01-26Sell2,0006,149$27.5155-1.026,149 (Direct)
Popovits Kimberly JPresident and CEO2012-01-25Sell5,0000$26.42132.13.07Link
Popovits Kimberly JPresident and CEO2012-01-24Sell5,0000$26.62133.12.29Link
Shak StevenChief Medical Officer2012-01-24Sell5,000382,778$26.74133.71.83382,778 (Direct)
Schorno Dean LCFO2012-01-17Sell1,00024,049$2828-2.7517,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-01-12Sell2,5007,750$27.5468.9-1.137,750 (Direct)
Scott Randal WExecutive Chairman2012-01-11Sell20,0000$27.46549.2-0.84Link
Shak StevenChief Medical Officer2011-12-22Sell5,000387,778$26.03130.24.61387,778 (Direct)
Scott Randal WExecutive Chairman2011-12-13Sell20,0000$27.29545.8-0.22Link
Cole G BradleyCOO2011-12-06Sell2,5007,750$28.5971.5-4.767,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-12-05Buy3,152192,064$28.1288.6-3.17
192,064 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-12-05Buy45,9771,306,281$27.661271.7-1.55
1,306,281 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-12-05Buy117,7516,901,703$28.123311.2-3.17
6,901,703 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-23Buy5,5311,260,304$25.91143.35.09
1,260,304 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-23Buy5,750188,912$25.94149.24.97
188,912 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-23Buy193,7396,783,952$25.915019.85.09
6,783,952 (Through Partnership)
Shak StevenChief Medical Officer2011-11-22Sell5,000392,778$26.07130.44.45392,778 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-16Buy64,5976,590,213$27.711790-1.73
6,590,213 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-16Buy2,550183,162$27.7170.7-1.73
183,162 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-16Buy4581,254,773$27.3512.5-0.44
1,254,773 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-14Buy10,106180,612$27.23275.20
180,612 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-14Buy249,3756,525,616$27.236790.50
6,525,616 (Through Partnership)
Scott Randal WExecutive Chairman2011-11-11Sell20,0000$27.24544.8-0.04Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-09Buy5421,254,315$26.7914.51.64
1,254,315 (Through Partnership)
Cole G BradleyCOO2011-11-08Sell2,5007,750$26.666.52.377,750 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-07Buy209,5126,276,241$25.945434.74.97
6,276,241 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-07Buy8,847170,506$25.94229.54.97
170,506 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-03Buy1201,253,773$24.482.911.23
1,253,773 (Through Partnership)
LIVINGSTON RANDALL SDirector2011-10-27Sell2,0006,149$22.0844.223.326,149 (Direct)
Shak StevenChief Medical Officer2011-10-24Sell5,000392,778$21.76108.825.14392,778 (Direct)
Scott Randal WExecutive Chairman2011-10-11Sell20,0000$22.83456.619.27Link
Cole G BradleyCOO2011-10-06Sell5,0007,750$22.31111.622.057,750 (Direct)
Scott Randal WExecutive Chairman2011-09-13Sell20,0000$20.81416.230.85Link
Cole G BradleyCOO2011-09-06Sell2,5007,750$22.0855.223.327,750 (Direct)
Shak StevenChief Medical Officer2011-08-24Sell5,000392,778$23.02115.118.29392,778 (Direct)
Scott Randal WExecutive Chairman2011-08-11Sell20,0000$24.44488.811.42Link
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.27.87,750 (Direct)
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.27.87,750 (Direct)
LIVINGSTON RANDALL SDirector2011-07-27Sell2,0006,149$26.4552.92.956,149 (Direct)
Shak StevenChief Medical Officer2011-07-25Sell5,000392,778$27.61138.1-1.38392,778 (Direct)
Scott Randal WExecutive Chairman2011-07-12Sell20,0001,503,444$27.36547.2-0.481,491,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Cole G BradleyCOO2011-07-06Sell5,0007,750$27.74138.7-1.847,750 (Direct)
Shak StevenChief Medical Officer2011-06-23Sell5,000392,778$27.12135.60.41392,778 (Direct)
Schorno Dean LCFO2011-06-15Sell1,00025,049$25.9125.95.0918,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-06-13Sell20,0001,523,444$25.69513.85.991,511,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-09Buy119194,415$26.193.13.97
194,415 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-06-09Buy4,388161,659$26.19114.93.97
161,659 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-09Buy203,6526,059,449$26.25335.73.93
6,059,449 (Through Partnership)
Cole G BradleyCOO2011-06-06Sell2,5007,750$26.1865.54.017,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-06-01Buy4,631157,271$27.34126.6-0.4
157,271 (Through Partnership)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-01Buy112194,296$27.353.1-0.44
194,296 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-01Buy181,6935,855,797$27.354969.3-0.44
5,855,797 (Through Partnership)
Shak StevenChief Medical Officer2011-05-25Sell5,000392,778$25.55127.86.58392,778 (Direct)
Schorno Dean LCFO2011-05-12Sell1,00026,049$26.4826.52.8319,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-05-11Sell20,0000$26.66533.22.14Link
Cole G BradleyCOO2011-05-09Sell2,5007,750$25.9364.85.017,750 (Direct)
LIVINGSTON RANDALL SDirector2011-04-27Sell2,0000$26.0452.14.57Link
Shak StevenChief Medical Officer2011-04-25Sell5,0000$25.38126.97.29Link
Popovits Kimberly JPresident and CEO2011-04-15Sell8,0000$25.49203.96.83Link
Schorno Dean LCFO2011-04-14Sell1,0000$25.3225.37.54Link
Scott Randal WExecutive Chairman2011-04-12Sell20,0000$25.96519.24.89Link
Cole G BradleyCOO2011-04-06Sell5,0000$26.91134.61.19Link
Shak StevenChief Medical Officer2011-03-24Sell5,0000$24.45122.311.37Link
Schorno Dean LCFO2011-03-15Sell1,0000$23.7923.814.46Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.312.1Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.312.1Link
Scott Randal WExecutive Chairman2011-03-11Sell20,0000$25.62512.46.28Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-10Buy70,8560$26.031844.44.61Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-08Buy9,6480$25.06241.88.66Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-08Buy349,5660$25.068760.18.66Link
Cole G BradleyCOO2011-03-08Sell2,5000$25.2363.17.93Link
COLELLA SAMUEL DDirector2011-03-03Sell34,3200$25.45873.46.99Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-02Buy160,3370$25.694119.15.99Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-02Buy4,4260$25.69113.75.99Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-02-25Buy158,3550$23.393703.916.42Link
14159 capital (GP), LLCDirector, 10% Owner2011-02-25Buy4,3700$23.39102.216.42Link
Shak StevenChief Medical Officer2011-02-24Sell5,0000$23.27116.417.02Link
Schorno Dean LCFO2011-02-15Sell1,0000$22.5122.520.97Link
Popovits Kimberly JPresident and CEO2011-02-15Sell8,0000$22.51180.120.97Link
Scott Randal WExecutive Chairman2011-02-11Sell20,0000$22.244422.66Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,000309,424$21.15169.228.75Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,0000$21.15169.228.75Link
Schorno Dean LCFO2011-01-13Sell1,27626,149$21.0626.929.3Link
Scott Randal WExecutive Chairman2011-01-11Sell20,0001,642,410$21.73434.625.31Link
Cole G BradleyCOO2011-01-06Sell5,0001,000$22.13110.723.05Link
Popovits Kimberly JPresident and CEO2010-12-16Sell8,000310,624$22.71181.719.9Link
Scott Randal WExecutive Chairman2010-12-13Sell20,0001,696,410$22.46449.221.24Link
Cole G BradleyCOO & CFO2010-12-13Sell2,5001,000$22.6456.620.27Link
Popovits Kimberly JPresident and CEO2010-11-16Sell8,000310,624$17.514055.6Link
Cole G BradleyCOO & CFO2010-11-11Sell2,5001,000$18.0445.150.94Link
Scott Randal WExecutive Chairman2010-11-11Sell20,0001,666,410$18.27365.449.04Link
Scott Randal WExecutive Chairman2010-10-12Sell20,0001,686,410$13.9527995.2Link
Popovits Kimberly JPresident and CEO2010-09-15Sell7,734310,624$15.1116.880.33Link
Scott Randal WExecutive Chairman2010-09-13Sell20,0001,706,410$14.87297.483.12Link
Cole G BradleyCOO & CFO2010-09-13Sell2,5001,000$15.0137.581.41Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-09Buy145134,196$14.812.183.86Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-09Buy5,2614,934,990$14.8177.983.86Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-02Buy65,4664,929,729$14.46946.688.31Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-02Buy1,807134,051$14.4626.188.31Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-30Buy3,415132,244$14.3749.189.49Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-30Buy123,7114,864,263$14.371777.789.49Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-23Buy150,4694,740,552$14.522184.887.53Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-23Buy4,153128,829$14.5260.387.53Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-18Buy530124,676$14.997.981.65Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-18Buy19,1874,590,083$14.99287.681.65Link
Popovits Kimberly JPresident and CEO2010-08-17Sell8,000288,116$15.07120.680.69Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-13Buy2,924124,146$14.8543.483.37Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-13Buy105,9104,570,896$14.851572.883.37Link
Cole G BradleyCOO & CFO2010-08-12Sell2,5001,000$1537.581.53Link
Scott Randal WExecutive Chairman2010-08-11Sell20,0001,726,410$14.71294.285.11Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-10Buy164,2424,464,986$14.612399.686.38Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-10Buy4,533121,222$14.6166.286.38Link
Baker JoffreChief Scientific Officer2010-08-09Sell4,629163,088$14.7568.384.61Link
Scott Randal WExecutive Chairman2010-07-13Sell20,0001,746,410$12.81256.2112.57Link
Baker JoffreChief Scientific Officer2010-07-07Sell4,629167,717$13.0560.4108.66Link
Scott Randal WExecutive Chairman2010-06-11Sell20,0001,766,410$14.1528392.44Link
Baker JoffreChief Scientific Officer2010-06-10Sell4,629172,346$14.056593.81Link
Popovits Kimberly JPresident and CEO2010-05-17Sell8,000310,624$15.78126.272.56Link
Cole G BradleyCOO & CFO2010-05-12Sell2,5001,000$15.8739.771.58Link
Scott Randal WExecutive Chairman2010-05-11Sell20,0001,776,410$15.61312.274.44Link
Baker JoffreChief Scientific Officer2010-05-10Sell4,629176,975$15.5171.875.56Link
Scott Randal WExecutive Chairman2010-04-13Sell20,0001,796,410$16.87337.461.41Link
Cole G BradleyCOO & CFO2010-04-12Sell5,0001,000$16.984.561.12Link
Baker JoffreChief Scientific Officer2010-04-12Sell4,629181,604$16.8878.161.32Link
Popovits Kimberly JPresident and CEO2010-03-16Sell20,000288,116$19.4538940Link
Scott Randal WExecutive Chairman2010-03-11Sell20,0001,800,646$19.338641.09Link
Cole G BradleyCOO & CFO2010-03-11Sell2,5001,000$19.3948.540.43Link
COLELLA SAMUEL DDirector2010-03-10Sell106,70085,050$19.452075.340Link
Baker JoffreChief Scientific Officer2010-03-08Sell4,629150,120$19.8391.837.32Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-19Buy3,645116,689$17.0562.159.71Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-19Buy132,0704,300,744$17.052251.859.71Link
Scott Randal WExecutive Chairman2010-02-11Sell20,0001,830,646$17.23344.658.04Link
Cole G BradleyCOO & CFO2010-02-11Sell2,5001,000$17.5143.855.51Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-10Buy9,437113,044$17.01160.560.08Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-10Buy341,8544,168,674$17.015814.960.08Link
Baker JoffreChief Scientific Officer2010-02-09Sell4,629145,491$17.1479.358.87Link
Cole G BradleyCOO & CFO2010-01-12Sell5,0001,000$17.2586.357.86Link
Baker JoffreChief Scientific Officer2010-01-11Sell4,629150,120$17.4780.955.87Link
Shak StevenChief Medical Officer2009-12-21Sell5,000388,278$20.12100.635.34Link
Popovits Kimberly JPresident and CEO2009-12-15Sell5,000313,506$20.3910233.55Link
Cole G BradleyCOO & CFO2009-12-14Sell2,0001,000$20.4240.833.35Link
Scott Randal WExecutive Chairman2009-12-11Sell12,0001,880,646$20.24242.934.54Link
Baker JoffreChief Scientific Officer2009-12-08Sell4,629154,749$20.2693.834.4Link
Popovits Kimberly JPresident and CEO2009-11-17Sell20,000318,506$19.21384.241.75Link
Cole G BradleyCOO & CFO2009-11-12Sell6653,000$20.0413.335.88Link
Scott Randal WExecutive Chairman2009-11-11Sell12,0001,892,646$19.99239.936.22Link
Baker JoffreChief Scientific Officer2009-11-10Sell4,629159,378$2092.636.15Link
Shak StevenChief Medical Officer2009-10-20Sell5,000393,278$20.65103.331.86Link
Popovits Kimberly JPresident and CEO2009-10-15Sell5,000338,506$20.42102.133.35Link
Scott Randal WExecutive Chairman2009-10-13Sell12,0001,904,646$20.66247.931.8Link
Baker JoffreChief Scientific Officer2009-10-07Sell4,629164,007$21.179828.63Link
Shak StevenChief Medical Officer2009-09-22Sell5,000398,278$21.13105.728.87Link
Popovits Kimberly JPresident and CEO2009-09-15Sell5,000343,506$20.73103.731.36Link
Scott Randal WExecutive Chairman2009-09-11Sell12,0001,916,646$20.6724831.74Link
Baker JoffreChief Scientific Officer2009-09-04Sell4,629168,636$20.1293.135.34Link
Shak StevenChief Medical Officer2009-08-25Sell5,000403,278$20.77103.931.1Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-17Buy1,839103,607$19.9836.736.29Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-17Buy66,6303,826,820$19.981331.336.29Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-17Buy34194,184$19.980.736.29Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-17Buy11,6571,253,653$19.98232.936.29Link
Popovits Kimberly JPresident and CEO2009-08-17Sell5,000348,506$19.5397.739.43Link
Cole G BradleyCOO & CFO2009-08-13Sell5,0003,000$2010036.15Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-12Buy15,8771,241,996$19.49309.439.71Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-12Buy45194,150$19.50.939.64Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-12Buy90,7543,760,190$19.491768.839.71Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-12Buy2,508101,768$19.4948.939.71Link
Scott Randal WExecutive Chairman2009-08-11Sell12,0001,928,646$19.4223340.22Link
Baker JoffreChief Scientific Officer2009-08-10Sell4,629173,265$19.4890.239.78Link
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.170.08
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.170.08
Scott Randal WExecutive Chairman2009-06-11Sell6,0001,940,646$18.27109.649.04
Baker JoffreChief Scientific Officer2009-06-08Sell4,629182,523$17.6981.953.93
Shak StevenChief Medical Officer2009-05-26Sell5,000408,278$199543.32
14159 capital (GP), LLCDirector, 10% Owner2009-05-21Buy1,10899,260$17.9719.951.53
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-21Buy90194,161$17.971.651.53
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-21Buy39,7783,669,436$17.97714.851.53
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-21Buy25194,105$17.970.451.53
Popovits Kimberly JPresident and CEO2009-05-15Sell5,000353,506$20.12100.635.34
Scott Randal WExecutive Chairman2009-05-12Sell12,0001,946,646$19.46233.539.93
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-11Buy88194,080$19.551.739.28
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-11Buy312194,071$19.556.139.28
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-11Buy137,4663,629,658$19.552687.539.28
14159 capital (GP), LLCDirector, 10% Owner2009-05-11Buy3,82798,152$19.5574.839.28
Baker JoffreChief Scientific Officer2009-05-08Sell4,629187,152$19.7291.338.08
Scott Randal WExecutive Chairman2009-04-14Sell12,0001,958,646$25.47305.66.91
Baker JoffreChief Scientific Officer2009-04-01Sell4,629191,781$25.271177.76
Scott Randal WExecutive Chairman2009-03-11Sell12,0001,970,646$19.4232.840.36
Baker JoffreChief Scientific Officer2009-03-03Sell4,629196,410$19.1388.642.34
Cole G BradleyCOO & CFO2009-02-17Sell5,0003,000$21.52107.626.53
Baker JoffreChief Scientific Officer2009-02-12Sell4,62922,226$20.695.432.18
Baker JoffreChief Scientific Officer2009-02-12Sell4,629201,039$20.695.432.18
Scott Randal WExecutive Chairman, Director2009-02-11Sell12,0001,982,646$20.85250.230.6
Baker JoffreChief Scientific Officer2009-01-12Sell4,62926,855$19.4189.840.29
Shak StevenChief Medical Officer2008-12-22Sell100413,278$20.17235
Baker JoffreChief Scientific Officer2008-12-10Sell4,62931,484$19.2589.141.45
Baker JoffreChief Scientific Officer2008-12-10Sell4,629205,668$19.2589.141.45
Scott Randal WCEO, Director2008-12-09Sell12,0001,955,298$18.4220.847.99
Baker JoffreChief Scientific Officer2008-11-12Sell4,62936,113$19.879237.04
Baker JoffreChief Scientific Officer2008-11-12Sell4,629210,297$19.879237.04
Scott Randal WCEO, Director2008-11-11Sell12,0001,967,298$20.05240.635.81
Cole G BradleyEVP & CFO2008-11-10Sell10,0004,000$20.17201.735
Scott Randal WCEO, Director2008-10-14Sell12,0001,979,298$20.36244.333.74
Baker JoffreChief Scientific Officer2008-10-01Sell9,25840,742$22.51208.420.97
Shak StevenChief Medical Officer2008-09-24Sell5,000413,378$22.67113.420.11
Scott Randal WCEO, Director2008-09-16Sell12,0001,991,298$21.79261.524.97
Shak StevenChief Medical Officer2008-08-26Sell5,000418,378$22.93114.718.75
Baker JoffreChief Scientific Officer2008-08-26Sell4,629214,926$22.6910520.01
Cole G BradleyEVP & CFO2008-08-18Sell9,2984,000$23.67220.115.04
Popovits Kimberly JPresident and COO2008-08-15Sell25,000358,506$24.2460612.33
Scott Randal WCEO, Director2008-08-12Sell12,0002,003,298$23.76285.114.6
Scott Randal WCEO, Director2008-07-15Sell12,0002,015,298$2125229.67
Baker JoffreChief Scientific Officer2008-07-01Sell4,629219,555$19.2689.241.38
Shak StevenChief Medical Officer2008-06-24Sell100423,378$20236.15
Scott Randal WCEO, Director2008-06-10Sell12,0002,027,298$19.9223936.7
Baker Brothers Life Sciences CDirector, 10% Owner2008-06-09Buy320,9833,492,192$19.916390.836.77
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-06-09Buy76,0151,226,119$19.911513.536.77
14159 capital (GP), LLCDirector, 10% Owner2008-06-09Buy10,29994,325$19.91205.136.77
Baker JoffreChief Scientific Officer2008-06-02Sell4,629228,813$17.9983.351.36
Scott Randal WCEO, Director2008-05-13Sell12,0002,039,298$18.7522545.23
Baker JoffreChief Scientific Officer2008-05-08Sell4,629233,442$19.2789.241.31
Scott Randal WCEO, Director2008-04-15Sell12,0002,051,298$17.22206.658.13
Scott Randal WCEO, Director2008-03-11Sell12,0002,063,298$18.84226.144.53
Baker JoffreChief Scientific Officer2008-03-05Sell4,629242,700$20.4894.832.96
Shak StevenChief Medical Officer2008-02-26Sell5,000423,478$20.23101.234.6
Cole G BradleyEVP & CFO2008-02-19Sell9,0008,298$22.58203.220.59
Scott Randal WCEO, Director2008-02-12Sell12,0002,075,298$23.01276.118.34
Baker JoffreChief Scientific Officer2008-02-11Sell4,629247,329$22.94106.218.7
Scott Randal WCEO, Director2008-01-15Sell12,0002,087,298$25.54306.56.62
Baker JoffreChief Scientific Officer2008-01-02Sell4,629251,958$22.66104.920.17
Baker JoffreChief Scientific Officer2007-12-03Sell4,6290$23.1106.917.88
Popovits Kimberly JPresident and COO2007-11-27Sell6,655383,506$22146.423.77
Scott Randal WCEO, Director2007-11-09Sell12,0002,111,299$23.07276.818.03
Baker JoffreChief Scientific Officer2007-11-08Sell4,629265,845$23.21107.417.32
Scott Randal WCEO2007-10-09Sell12,0002,123,299$20.16241.935.07
Baker JoffreChief Scientific Officer2007-10-01Sell4,629270,474$19.8491.837.25
Scott Randal WCEO2007-09-11Sell12,0002,135,299$19.69236.338.29
Scott Randal WCEO, Director2007-09-11Sell12,0002,135,299$19.7236.438.22
Baker JoffreChief Scientific Officer2007-09-10Sell4,629275,103$19.5790.639.14
Goldberg Michael DDirector2007-08-23Buy5,3505,350$18.76100.445.15
Scott Randal WCEO2007-08-15Sell12,0002,147,299$19.91238.936.77
Baker JoffreChief Scientific Officer2007-08-08Sell4,629279,732$19.449040.07
Scott Randal WCEO2007-07-18Sell12,0002,159,299$21.18254.228.56
Baker JoffreChief Scientific Officer2007-07-02Sell4,629284,361$19.018843.24
Scott Randal WCEO2007-06-19Sell12,0002,171,299$19.16229.942.12
Baker JoffreChief Scientific Officer2007-06-01Sell4,629288,990$17.5681.355.07
Baker Bros. Capital (GP), LLCDirector2007-05-30Buy545193,992$16.328.966.85
Baker Biotech Capital (GP), LLDirector2007-05-30Buy81,1811,150,104$16.321324.966.85
Baker Brothers Life Sciences CDirector2007-05-30Buy214,0993,171,209$16.323494.166.85
14159 capital (GP), LLCDirector2007-05-30Buy6,80784,026$16.32111.166.85
14159 capital (GP), LLCDirector2007-05-24Buy16,26177,219$16.59269.864.14
Baker Brothers Life Sciences CDirector2007-05-24Buy511,5532,957,110$16.598486.764.14
Baker Biotech Capital (GP), LLDirector2007-05-24Buy193,9661,068,923$16.593217.964.14
Baker Bros. Capital (GP), LLCDirector2007-05-24Buy1,303193,447$16.5921.664.14
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.975.68
14159 capital (GP), LLCDirector2007-05-21Buy22,49160,958$15.5348.675.68
14159 capital (GP), LLCDirector2007-05-21Buy160,958$15.5075.68
Baker Brothers Life Sciences CDirector2007-05-21Buy707,4582,445,557$15.510965.675.68
Baker Biotech Capital (GP), LLDirector2007-05-21Buy268,248874,957$15.54157.875.68
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.975.68
Scott Randal WCEO2007-05-08Sell12,0002,183,299$16.62199.463.84
Baker JoffreChief Scientific Officer2007-05-08Sell4,629293,619$16.3175.566.95
Scott Randal WCEO2007-04-10Sell12,0002,195,299$17.27207.257.67
Baker JoffreChief Scientific Officer2007-04-02Sell4,629298,248$17.1679.458.68
Baker / Tisch Capital (GP), LLDirector2007-03-09Buy3,181193,759$18.2858.148.96
Baker Bros. Capital (GP), LLCDirector2007-03-09Buy376190,341$18.286.948.96
Baker Biotech Capital (GP), LLDirector2007-03-09Buy62,325606,709$18.281139.348.96
Baker Brothers Life Sciences CDirector2007-03-09Buy168,5601,738,099$18.283081.348.96
14159 capital (GP), LLCDirector2007-03-09Buy5,37538,467$18.2898.348.96
Scott Randal WCEO2007-03-06Sell12,0002,207,299$18.35220.248.39
Baker Bros. Capital (GP), LLCDirector2007-03-02Buy119189,965$18.092.250.53
14159 capital (GP), LLCDirector2007-03-02Buy1,70733,092$18.0930.950.53
Baker / Tisch Capital (GP), LLDirector2007-03-02Buy1,072190,578$18.119.450.44
Baker Biotech Capital (GP), LLDirector2007-03-02Buy19,795544,384$18.09358.150.53
Baker Brothers Life Sciences CDirector2007-03-02Buy53,5331,569,539$18.09968.450.53
Baker JoffreChief Scientific Officer2007-03-01Sell4,629302,877$18.1884.249.78
MYERS WOODROW A JRDirector2007-02-21Buy2,00012,000$19.6339.338.72
Baker Brothers Life Sciences CDirector2007-02-16Buy25,4121,516,006$18.54471.146.87
Baker Biotech Capital (GP), LLDirector2007-02-16Buy9,396524,589$18.54174.246.87
Baker / Tisch Capital (GP), LLDirector2007-02-16Buy525189,506$18.549.746.87
14159 capital (GP), LLCDirector2007-02-16Buy81131,385$18.541546.87
Baker Bros. Capital (GP), LLCDirector2007-02-16Buy56189,846$18.54146.87
Baker Bros. Capital (GP), LLCDirector2007-02-14Buy579189,790$18.2510.649.21
Baker / Tisch Capital (GP), LLDirector2007-02-14Buy5,346188,981$18.2597.649.21
Baker Biotech Capital (GP), LLDirector2007-02-14Buy95,783515,193$18.25174849.21
14159 capital (GP), LLCDirector2007-02-14Buy8,25630,574$18.25150.749.21
Baker Brothers Life Sciences CDirector2007-02-14Buy259,0441,490,594$18.254727.649.21
Scott Randal WCEO2007-02-13Sell12,0002,219,299$18.12217.450.28
Baker JoffreChief Scientific Officer2007-02-08Sell4,629307,506$18.9787.843.54
Baker / Tisch Capital (GP), LLDirector2006-12-06Buy642183,635$21.5813.926.18
Baker Brothers Life Sciences CDirector2006-12-06Buy34,1731,231,550$21.58737.526.18
14159 capital (GP), LLCDirector2006-12-06Buy1,12022,318$21.5824.226.18
Baker Biotech Capital (GP), LLDirector2006-12-06Buy12,237419,410$21.58264.126.18
MYERS WOODROW A JRDirector2006-12-05Buy10,00010,000$21.97219.723.94
Baker / Tisch Capital (GP), LLDirector2006-12-05Buy9,096182,993$20.6187.432.18
Baker Biotech Capital (GP), LLDirector2006-12-05Buy173,441407,173$20.63572.932.18
14159 capital (GP), LLCDirector2006-12-05Buy15,88021,198$20.6327.132.18
Baker Brothers Life Sciences CDirector2006-12-05Buy484,3331,197,377$20.69977.332.18
14159 capital (GP), LLCDirector2006-09-08Buy5,3185,318$14.0574.793.81Link
Baker Biotech Capital (GP), LLDirector2006-09-08Buy75,246233,732$14.051057.293.81Link
Baker Brothers Life Sciences CDirector2006-09-08Buy237,236713,044$14.053333.293.81Link
Baker Biotech Capital III (GP)10% Owner2005-10-04Buy136,316252,529$121635.8126.92Link
Baker Biotech Capital II (GP),10% Owner2005-10-04Buy38,684181,478$12464.2126.92Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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