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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Marvin S. Hausman,M.D.N/A2,389,9392.81%2005-01-11
Dr. Christopher M. Starr,PhDDirector706,0650.83%2015-05-19
Dr. Todd C. Zankel,PhDChief Scientific Officer651,8660.77%2012-09-04
Gosse B. Bruinsma,M.D.N/A535,5000.63%2004-12-17
Dr. William T. Comer,PhDN/A175,2560.21%2007-05-18
Louis G. CornacchiaN/A171,9330.2%2004-12-17
Mr. Steven B. RatoffN/A81,2080.1%2006-12-26
Dr. Suzanne L. BruhnDirector48,437less than 0.1%2015-09-09
Ms. Julie Anne SmithN/A37,950less than 0.1%2014-12-03
Thomas (Ted) E. DaleyChief Business Officer34,719less than 0.1%2015-06-18

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Bruhn Suzanne LouiseDirector2015-09-09Sell18,25848,437$12.47227.7-70.0148,437 (Direct)
Anderson RaymondDirector2015-09-02Sell4,9166,695$12.5161.5-70.16,695 (Direct)
Anderson RaymondDirector2015-08-31Sell8,0846,695$12.52101.2-70.136,695 (Direct)
Keltner LlewDirector2015-07-01Sell50,0006,695$16.05802.5-76.76,695 (Direct)
Daley Thomas EChief Business Officer2015-06-18Sell35,00034,719$15525-75.0734,719 (Direct)
Bruhn Suzanne LouiseDirector2015-06-10Sell30,0006,695$13.45403.5-72.196,695 (Direct)
Daley Thomas EChief Business Officer2015-05-20Sell10,00064,719$12120-68.8364,719 (Direct)
FRANKLIN RICHARD LDirector2015-05-04Sell10,0001,674$9.6196.1-61.081,674 (Direct)
FRANKLIN RICHARD LDirector2015-04-02Sell10,0001,674$10.37103.7-63.931,674 (Direct)
Anderson RaymondDirector2015-03-24Sell21,6191,674$12259.4-68.831,674 (Direct)
STARR CHRISTOPHER MDirector2015-03-23Sell20,033701,044$11.62232.8-67.81701,044 (Direct)
STARR CHRISTOPHER MDirector2015-03-16Sell30,021701,044$11.71351.5-68.06701,044 (Direct)
SAGER ERICHDirector2015-03-05Sell25,0004,005$10.71267.8-65.084,005 (Direct)
FRANKLIN RICHARD LDirector2015-03-02Sell10,0000$9.1891.8-59.26Link
STARR CHRISTOPHER MDirector2015-02-24Sell30,000701,044$9.52285.6-60.71701,044 (Direct)
STARR CHRISTOPHER MDirector2015-02-17Sell30,000701,044$9.37281.1-60.09701,044 (Direct)
FRANKLIN RICHARD LDirector2015-02-02Sell7,1090$9.265.4-59.35Link
STARR CHRISTOPHER MDirector2015-01-22Sell30,000699,370$9.45283.5-60.42699,370 (Direct)
STARR CHRISTOPHER MDirector2015-01-15Sell30,000699,370$9.73291.9-61.56699,370 (Direct)
STARR CHRISTOPHER MCEO
(Click for the stocks that their CEOs have bought)
2014-12-22Sell30,000699,370$9270-58.44699,370 (Direct)
STARR CHRISTOPHER MCEO2014-12-15Sell30,000699,370$8.15244.5-54.11699,370 (Direct)
STARR CHRISTOPHER MCEO2014-11-24Sell30,000699,370$9.97299.1-62.49699,370 (Direct)
STARR CHRISTOPHER MCEO2014-11-17Sell30,000699,370$9.91297.3-62.26699,370 (Direct)
SAGER ERICHDirector2014-11-12Sell46,96627,331$10.35486.1-63.8627,331 (Direct)
STARR CHRISTOPHER MCEO2014-10-22Sell30,000699,370$10.25307.5-63.51699,370 (Direct)
STARR CHRISTOPHER MCEO2014-10-15Sell30,000699,370$10.04301.2-62.75699,370 (Direct)
STARR CHRISTOPHER MCEO2014-09-23Sell30,000699,370$10.21306.3-63.37699,370 (Direct)
STARR CHRISTOPHER MCEO2014-09-16Sell32,896699,370$10.6348.7-64.72699,370 (Direct)
Anderson RaymondDirector2014-09-10Sell10,0000$10.81108.1-65.4Link
SAGER ERICHDirector2014-08-25Sell10,00074,297$11.01110.1-66.0374,297 (Direct)
Anderson RaymondDirector2014-07-07Sell27,5000$11.21308.3-66.64Link
Keltner LlewDirector2014-07-07Sell10,0000$11.21112.1-66.64Link
Keltner LlewDirector2014-05-30Buy1000$8.370.8-55.32Link
Erbez GeorgiaCFO2014-05-13Buy16,10019,600$7.9127.2-52.6616,100 (Direct)
1,800 (Trustee for the benefit of Jake Phillip Erbez)
1,700 (Trustee for the benefit of Alexander D. Erbez)
SAMANT VIJAY BDirector2014-04-07Sell5,0000$8.5943-56.46Link
STARR CHRISTOPHER MCEO2014-03-17Sell19,316699,370$10.79208.4-65.34699,370 (Direct)
Walbert Timothy PDirector2014-03-13Sell5,5210$15.2284-75.43Link
Bruhn Suzanne LouiseDirector2014-03-13Sell2,7600$15.2142-75.41Link
Keltner LlewDirector2014-03-07Sell10,0000$15.73157.3-76.22Link
Anderson RaymondDirector2014-03-07Sell12,5000$15.72196.5-76.21Link
FRANKLIN RICHARD LDirector2014-03-03Sell10,7150$15.91170.5-76.49Link
STARR CHRISTOPHER MCEO2014-02-18Sell25,000699,370$15.26381.5-75.49699,370 (Direct)
SAGER ERICHDirector2014-02-18Sell10,00084,297$15.17151.7-75.3584,297 (Direct)
Bruhn Suzanne LouiseDirector2014-02-13Sell2,7600$14.9841.3-75.03Link
SAMANT VIJAY BDirector2014-02-07Sell5,0000$15.0475.2-75.13Link
STARR CHRISTOPHER MCEO2014-01-15Sell25,000699,370$15.42385.5-75.75699,370 (Direct)
Walbert Timothy PDirector2014-01-13Sell5,5200$15.0683.1-75.17Link
Bruhn Suzanne LouiseDirector2014-01-13Sell2,7600$15.0541.5-75.15Link
Daley Thomas EChief Business Officer2014-01-09Sell15,00039,906$14.17212.6-73.6139,906 (Direct)
Keltner LlewDirector2014-01-07Sell10,0000$13.25132.5-71.77Link
Anderson RaymondDirector2014-01-07Sell10,0000$13.25132.5-71.77Link
FRANKLIN RICHARD LDirector2014-01-02Sell10,7150$13.12140.6-71.49Link
Bruhn Suzanne LouiseDirector2013-12-16Sell2,7600$13.1936.4-71.65Link
STARR CHRISTOPHER MCEO2013-12-16Sell25,000699,370$13.36334-72.01699,370 (Direct)
SAMANT VIJAY BDirector2013-12-09Sell5,0000$13.8669.3-73.02Link
STARR CHRISTOPHER MCEO2013-11-15Sell25,000699,370$12.31307.8-69.62699,370 (Direct)
Walbert Timothy PDirector2013-11-13Sell5,5210$12.4468.7-69.94Link
Bruhn Suzanne LouiseDirector2013-11-13Sell2,7600$1335.9-71.23Link
Daley Thomas EChief Business Officer2013-11-11Sell15,00054,906$12.79191.9-70.7654,906 (Direct)
Keltner LlewDirector2013-11-07Sell10,0000$14.05140.5-73.38Link
Anderson RaymondDirector2013-11-07Sell15,0000$14.04210.6-73.36Link
FRANKLIN RICHARD LDirector2013-11-04Sell10,7150$14.88159.4-74.87Link
STARR CHRISTOPHER MCEO2013-10-15Sell25,000699,370$13.77344.3-72.84699,370 (Direct)
Bruhn Suzanne LouiseDirector2013-10-14Sell2,7600$13.5837.5-72.46Link
SAMANT VIJAY BDirector2013-10-07Sell5,0000$14.7673.8-74.66Link
STARR CHRISTOPHER MCEO2013-09-16Sell25,000699,370$14.21355.3-73.68699,370 (Direct)
SAGER ERICHDirector2013-09-16Sell17,000130,727$14.21241.6-73.68130,727 (Direct)
Walbert Timothy PDirector2013-09-13Sell5,5200$14.0777.7-73.42Link
Bruhn Suzanne LouiseDirector2013-09-13Sell2,7600$14.0738.8-73.42Link
FRANKLIN RICHARD LDirector2013-09-09Sell10,7150$14.24152.6-73.74Link
Anderson RaymondDirector2013-09-09Sell15,0000$14.24213.6-73.74Link
Daley Thomas EPresident, Raptor Therapeutics2013-09-09Sell25,00069,906$14.28357-73.8169,906 (Direct)
Erbez GeorgiaCFO2013-08-30Sell7,4000$13.4299.3-72.13Link
Hyperion Trading Segregated Po10% Owner2013-08-23Sell279,3005,954,700$12.313438.2-69.625,954,700 (Direct)
Hyperion Trading Segregated Po10% Owner2013-08-13Sell616,5366,234,000$7.444587-49.736,234,000 (Direct)
Hyperion Trading Segregated Po10% Owner2013-04-05Sell243,9616,700,536$5.771407.7-35.186,700,536 (Direct)
STARR CHRISTOPHER MCEO2012-12-31Sell10,088699,370$5.6857.3-34.15699,370 (Direct)
Hyperion Trading Segregated Po10% Owner2012-12-31Buy1,266,1856,442,685$5.56964-326,442,685 (Direct)
Anderson RaymondDirector2012-12-28Sell2,0000$5.511-32Link
Daley Thomas EPresident, Raptor Therapeutics2012-12-17Sell3,33384,906$5.4518.2-31.3884,906 (Direct)
SAGER ERICHDirector2012-12-17Sell14,908108,074$5.4180.7-30.87108,074 (Direct)
SAGER ERICHDirector2012-11-27Sell3,629111,998$518.1-25.2111,998 (Direct)
SAGER ERICHDirector2012-11-26Sell11,279115,627$556.4-25.2115,627 (Direct)
Keltner LlewDirector2012-11-26Sell9690$54.8-25.2Link
Daley Thomas EPresident, Raptor Therapeutics2012-10-15Sell3,33388,239$5.2217.4-28.3588,239 (Direct)
Anderson RaymondDirector2012-10-01Sell2,0000$5.5811.2-32.97Link
STARR CHRISTOPHER MCEO2012-09-28Sell10,085699,370$5.3954.4-30.61699,370 (Direct)
SAGER ERICHDirector2012-09-17Sell14,908219,757$5.4180.7-30.87219,757 (Direct)
Keltner LlewDirector2012-09-17Sell9670$5.495.3-31.88Link
Anderson RaymondDirector2012-09-12Sell2,0000$5.511-32Link
Zankel ToddChief Scientific Officer2012-09-04Sell842651,866$54.2-25.2651,866 (Direct)
SAGER ERICHDirector2012-08-31Sell7,700223,681$538.5-25.2223,681 (Direct)
Zankel ToddChief Scientific Officer2012-08-31Sell10,148652,708$550.7-25.2652,708 (Direct)
SAGER ERICHDirector2012-08-29Sell3,284223,681$5.0116.5-25.35223,681 (Direct)
Zankel ToddChief Scientific Officer2012-08-29Sell10,136659,214$5.0150.8-25.35659,214 (Direct)
Tsuchimoto Kim RCFO2012-08-29Sell3,510582$517.6-25.2582 (Direct)
Zankel ToddChief Scientific Officer2012-08-27Sell287669,350$51.4-25.2669,350 (Direct)
Daley Thomas EPresident, Raptor Therapeutics2012-08-27Sell3,33391,572$516.7-25.291,572 (Direct)
SAGER ERICHDirector2012-08-27Sell3,808223,681$519-25.2223,681 (Direct)
Tsuchimoto Kim RCFO2012-08-27Sell49582$50.2-25.2582 (Direct)
SAGER ERICHDirector2012-08-01Sell116227,489$50.6-25.2227,489 (Direct)
Keltner LlewDirector2012-08-01Sell9670$54.8-25.2Link
STARR CHRISTOPHER MCEO2012-06-29Sell10,085699,370$5.656.5-33.21699,370 (Direct)
Tsuchimoto Kim RCFO2012-06-15Sell3,559582$5.7720.5-35.18582 (Direct)
Daley Thomas EPresident, Raptor Therapeutics2012-06-15Sell3,33394,905$5.7719.2-35.1894,905 (Direct)
Hyperion Trading Segregated Po10% Owner2012-06-13Sell2,406,5002,503,787$5.4413091.4-31.252,503,787 (Direct)
Anderson RaymondDirector2012-06-08Sell1,9650$5.510.8-32Link
Anderson RaymondDirector2012-06-07Sell350$5.50.2-32Link
Keltner LlewDirector2012-05-15Sell9670$5.495.3-31.88Link
SAGER ERICHDirector2012-05-15Sell14,908227,605$5.5482.6-32.49227,605 (Direct)
Zankel ToddChief Scientific Officer2012-05-01Sell21,413669,350$5.84125.1-35.96669,350 (Direct)
Daley Thomas EPresident, Raptor Therapeutics2012-04-16Sell3,33398,238$6.0520.2-38.1898,238 (Direct)
Tsuchimoto Kim RCFO2012-04-16Sell3,559582$6.0521.5-38.18582 (Direct)
STARR CHRISTOPHER MCEO2012-04-02Sell10,0851,082,673$6.7267.8-44.351,082,673 (Direct)
Anderson RaymondDirector2012-04-02Sell6,128388,747$6.7241.2-44.35388,747 (Direct)
SAGER ERICHDirector2012-04-02Sell14,911507,512$6.73100.4-44.43507,512 (Direct)
SAGER ERICHDirector2012-04-02Sell14,911231,529$6.73100.4-44.43231,529 (Direct)
STARR CHRISTOPHER MCEO2012-04-02Sell10,085699,370$6.7267.8-44.35699,370 (Direct)
Anderson RaymondDirector2012-04-02Sell6,1280$6.7241.2-44.35Link
Keltner LlewDirector2012-03-15Sell9670$6.996.8-46.49Link
Anderson RaymondDirector2012-02-28Sell6,1280$7.2944.7-48.7Link
Daley Thomas EPresident, Raptor Therapeutics2012-02-15Sell3,333101,571$7.7425.8-51.68101,571 (Direct)
Tsuchimoto Kim RCFO2012-02-15Sell3,559582$7.7427.5-51.68582 (Direct)
Keltner LlewDirector2012-02-15Sell9670$7.747.5-51.68Link
Zankel ToddChief Scientific Officer2012-02-09Sell21,415686,834$7.73165.5-51.62686,834 (Direct)
ALTA PARTNERS2009-09-08Sell42,209538$0.229.3-0.04Link
Alta Partners III, Inc.2009-09-08Sell42,209538$0.229.3-0.04Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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