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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Remi BarbierN/A4,369,7319.47%2014-07-14
Sanford R. RobertsonN/A438,3620.95%2014-03-21
Nadav Friedmann,M.D.N/A359,8930.78%2014-11-18
Peter S. RoddyN/A103,0930.22%2014-07-14
Grant L. Schoenhard,PhDN/A78,5510.17%2014-07-11
Michael J. O'Donnell,Esq.N/A32,118less than 0.1%2014-03-21
Robert Z. Gussin,PhDN/A27,360less than 0.1%2014-05-27

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
ROBERTSON SANFORDDirector2013-11-06Buy50,000369,727$3.73186.5-45.04369,727 (Direct)
FRIEDMANN NADAVCOO2011-10-18Sell25,000259,255$4.44111-53.83259,255 (Direct)
FRIEDMANN NADAVCOO2011-10-04Sell25,000284,255$4.81120.25-57.38284,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-10-04Sell382,0004,263,076$4.591753.38-55.344,263,076 (Direct)
FRIEDMANN NADAVCOO2011-09-15Sell25,000309,255$4.89122.25-58.08309,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-08-08Sell44,4174,645,076$4.2186.55-51.194,645,076 (Direct)
BARBIER REMICEO, Chairman of the Board, 10% Owner
(Click for the stocks that their CEOs have bought)
2011-08-08Buy5,0005,948,053$4.2221.1-51.425,948,053 (Direct)
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-10-04Sell50,0005,929,587$6.2310-66.94Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-07Sell28,5975,979,587$5.69162.72-63.97Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-02Sell21,4036,008,184$5.81124.35-64.72Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-09Sell19,4696,029,587$5.64109.81-63.65Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-04Sell22,3916,049,056$5.71127.85-64.1Link
SCHOENHARD GRANTChief Scientific Officer2010-07-16Sell1,50048,157$5.548.31-63Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-07Sell27,2436,071,447$5.35145.75-61.68Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-02Sell22,7576,098,690$5.42123.34-62.18Link
SCHOENHARD GRANTChief Scientific Officer2010-06-16Sell1,50048,187$5.458.18-62.39Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-06-03Sell50,0006,121,447$5.53276.5-62.93Link
SCHOENHARD GRANTChief Scientific Officer2010-05-27Sell10,97948,187$5.7463.02-64.29Link
SCHOENHARD GRANTChief Scientific Officer2010-05-19Sell2,48648,187$5.7714.34-64.47Link
SCHOENHARD GRANTChief Scientific Officer2010-05-18Sell13,03548,187$5.7775.21-64.47Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-06Sell6,5766,171,447$5.6136.89-63.46Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-05Sell43,4246,178,023$5.91256.64-65.31Link
FRIEDMANN NADAVCOO2010-05-04Sell15,000275,951$5.9589.25-65.55Link
SCHOENHARD GRANTChief Scientific Officer2010-04-16Sell26,50048,187$6.29166.69-67.41Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-04-07Sell5,8006,221,447$6.2336.13-67.09Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-04-06Sell32,2006,227,247$6.25201.25-67.2Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-04-01Sell12,0006,259,447$6.1673.92-66.72Link
FRIEDMANN NADAVCOO2010-04-01Sell15,000287,195$6.1792.55-66.77Link
SCHOENHARD GRANTChief Scientific Officer2010-03-16Sell35,00048,187$6.13214.55-66.56Link
O DONNELL MICHAEL JDirector2010-03-11Sell25,0005,775$6.14153.5-66.61Link
BARBIER REMICEO and Chair of Board, 10% Owner2010-03-03Sell5,4436,271,447$6.1333.37-66.56Link
BARBIER REMICEO and Chair of the Board, 10% Owner2010-03-02Sell44,5576,276,890$6.07270.46-66.23Link
BARBIER REMICEO, President, Chairman of Bd, 10% Owner2010-02-02Sell50,0006,350,247$5.32266-61.47Link
BARBIER REMICEO, Chairman of Board, 10% Owner2010-01-06Sell50,0006,372,475$5.39269.5-61.97Link
FRIEDMANN NADAVCOO2009-11-16Sell15,000302,258$575-59Link
BARBIER REMICEO,, 10% Owner2009-11-05Sell50,0006,472,475$4.83241.5-57.56Link
BARBIER REMICEO, 10% Owner2009-10-02Sell20,0006,552,475$5.1102-59.8Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-09-29Sell3,076,9153,230,204$4.9815323.04-58.84Link
BARBIER REMICEO, 10% Owner2009-09-11Sell23,2006,599,275$5.23121.34-60.8Link
RODDY PETER SCFO2009-08-31Sell40,00054,783$5.08203.2-59.65Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-08-07Sell1,663,0006,307,119$3.966585.48-48.23Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-14Sell90,7787,970,119$4.23383.99-51.54
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.44-55.24
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.44-55.24
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-15Sell195,9215,810,453$5.07993.32-59.57
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-15Sell285,7038,428,897$5.071448.51-59.57
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-10Sell310,5216,006,374$5.271636.45-61.1
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-10Sell461,2748,714,600$5.272430.91-61.1
BARBIER REMIPresident and CEO, 10% Owner2009-06-05Sell50,0006,644,075$5.26263-61.03
BARBIER REMICEO and Chairman of the Board, 10% Owner2009-05-16Sell26,8006,572,475$5.23140.16-60.8Link
RODDY PETER SVice President & CFO2009-05-01Buy3,37454,783$3.7712.72-45.62
FRIEDMANN NADAVCOO2009-05-01Buy3,374317,258$3.7712.72-45.62
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-04-06Sell900,0009,175,874$4.153735-50.6
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-04-06Sell621,8606,316,895$4.152580.72-50.6
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-03-02Sell1,000,00010,075,874$3.583580-42.74
BARBIER REMIPresident and CEO, Director, 10% Owner2009-02-03Sell50,0006,694,075$6.46323-68.27
BARBIER REMIPresident and CEO, Director, 10% Owner2009-01-05Sell50,0006,744,075$6.13306.5-66.56
BARBIER REMIPresident and CEO, Director, 10% Owner2008-12-02Sell50,0006,794,075$8.58429-76.11
BARBIER REMIPresident and CEO, Director, 10% Owner2008-11-04Sell50,0006,844,075$8.81440.5-76.73
BARBIER REMIPresident and CEO, Director, 10% Owner2008-10-02Sell50,0006,896,575$9.76488-79
BARBIER REMIPresident and CEO, Director, 10% Owner2008-09-03Sell50,0006,850,200$9.41470.5-78.21
BARBIER REMIPresident and CEO, Director, 10% Owner2008-08-04Sell50,0006,775,200$8.34417-75.42
BARBIER REMIPresident and CEO, Director, 10% Owner2008-07-02Sell50,0006,825,200$7.71385.5-73.41
BARBIER REMIPresident and CEO, Director, 10% Owner2008-06-03Sell50,0006,875,200$8.04402-74.5
BARBIER REMIPresident and CEO, Director, 10% Owner2008-05-02Sell50,0006,925,200$7.38369-72.22
RODDY PETER SVice President and CFO2008-05-01Buy3,26825,709$6.320.59-67.46
FRIEDMANN NADAVChief Operating & Med. Officer, Director2008-05-01Buy3,267208,572$6.320.58-67.46
BARBIER REMIPresident and CEO, Director, 10% Owner2008-04-02Sell50,0006,975,200$8.59429.5-76.14
BARBIER REMIPresident and CEO, Director, 10% Owner2008-03-04Sell50,0007,041,200$8.16408-74.88
EASTBOURNE CAPITAL MANAGEMENT10% Owner2008-02-29Buy174,70011,075,874$9.111591.52-77.5
BARBIER REMIPresident and CEO, Director, 10% Owner2008-02-04Sell50,0007,091,200$8.88444-76.91
BARBIER REMIPresident and CEO, Director, 10% Owner2008-01-03Sell50,0007,141,200$10.19509.5-79.88
BARBIER REMIPresident and CEO, Director, 10% Owner2007-12-04Sell50,0007,191,200$10.26513-80.02
BARBIER REMIPresident and CEO, Director, 10% Owner2007-11-02Sell50,0007,241,200$10.91545.5-81.21
BARBIER REMIPresident and CEO2007-10-02Sell50,0007,291,200$9.7485-78.87
BARBIER REMIPresident and CEO2007-09-05Sell50,0007,341,200$9.53476.5-78.49
BARBIER REMIPresident and CEO2007-08-02Sell50,0007,391,200$8.45422.5-75.74
BARBIER REMIPresident and CEO2007-07-03Sell50,0001,441,200$8.91445.5-76.99
BARBIER REMIPresident and CEO2007-07-03Sell50,0007,441,200$8.91445.5-76.99
RODDY PETER SVice President and CFO2007-06-11Sell10,00021,415$8.1781.7-74.91
BARBIER REMIPresident and CEO2007-06-04Sell50,0007,491,200$8.39419.5-75.57
BARBIER REMIPresident and CEO2007-05-02Sell50,0007,541,200$8.2410-75
RODDY PETER SCFO2007-04-10Sell10,00016,757$7.9779.7-74.28
BARBIER REMIPresident and CEO2007-04-03Sell50,0007,591,200$7.89394.5-74.02
RODDY PETER SChief Financial Officer2007-03-12Sell10,00016,757$7.3973.9-72.26
BARBIER REMIPresident and CEO2007-03-02Sell50,0007,641,200$7.67383.5-73.27
FRIEDMANN NADAVChief Operating & Med. Officer2007-02-28Sell4,000150,596$7.8531.4-73.89
BARBIER REMIPresident and CEO2007-02-16Sell50,0007,705,200$8.41420.5-75.62
RODDY PETER SChief Financial Officer2007-02-12Sell10,00016,757$8.5485.4-76
FRIEDMANN NADAVChief Operating & Med. Officer2007-01-31Sell4,000154,596$8.935.6-76.97
RODDY PETER SChief Financial Officer2007-01-10Sell10,00016,757$8.686-76.16
FRIEDMANN NADAVChief Operating & Med. Officer2006-12-29Sell4,000158,596$9.1336.52-77.55
RODDY PETER SChief Financial Officer2006-12-11Sell10,00016,757$8.5585.5-76.02
BARBIER REMIPresident and CEO2006-12-04Sell35,0007,755,200$8.55299.25-76.02
FRIEDMANN NADAVChief Operating & Med. Officer2006-11-30Sell4,000162,596$8.5934.36-76.14
RODDY PETER SChief Financial Officer2006-11-10Sell10,00020,757$8.0180.1-74.41
BARBIER REMIPresident and CEO2006-11-06Sell35,0007,790,200$8.28289.8-75.24
FRIEDMANN NADAVOperating & Med. Officer2006-10-31Sell4,000165,275$8.3233.28-75.36
RODDY PETER SChief Financial Officer2006-10-10Sell10,00016,155$8.4184.1-75.62
BARBIER REMIPresident and CEO2006-10-09Sell35,0007,825,200$8.56299.6-76.05
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-19Buy2,9005,666,732$7.8822.85-73.98Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-14Buy7005,663,832$7.885.52-73.98Link
RODDY PETER SCFO2006-09-11Sell10,00016,155$7.8678.6-73.92Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-11Buy4,0645,663,132$7.8832.02-73.98Link
BARBIER REMIPresident and CEO, 10% Owner2006-09-05Sell35,0007,860,200$8.39293.65-75.57Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-08-31Sell4,000173,275$8.3733.48-75.51Link
RODDY PETER SCFO2006-08-10Sell10,00016,155$8.8388.3-76.78Link
BARBIER REMIPresident & CEO, 10% Owner2006-08-07Sell35,0007,895,200$8.56299.6-76.05Link
RODDY PETER SCFO2006-07-10Sell10,00016,155$8.3383.3-75.39Link
BARBIER REMIPresident and CEO, 10% Owner2006-07-03Sell35,0007,930,200$8.38293.3-75.54Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-19Buy81,4005,659,068$7.79634.11-73.68Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-16Buy114,3005,577,668$7.86898.4-73.92Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-14Buy26,3005,463,368$7.93208.56-74.15Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-13Buy72,5175,437,068$8.01580.86-74.41Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-12Buy2,0005,364,551$8.0416.08-74.5Link
RODDY PETER SCFO2006-06-12Sell10,00016,155$8.1381.3-74.78Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-08Buy42,6005,362,551$8.15347.19-74.85Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-06Buy3,8005,319,951$8.1931.12-74.97Link
BARBIER REMIPresident and CEO, 10% Owner2006-06-05Sell35,0007,965,200$8.68303.8-76.38Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-25Buy3,0655,316,151$8.1925.1-74.97Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-24Buy37,4005,313,086$8.19306.31-74.97Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-22Buy21,7005,275,686$8.19177.72-74.97Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-19Buy1,4005,253,986$8.1911.47-74.97Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-18Buy20,9775,252,586$8.19171.8-74.97Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-17Buy83,7005,231,609$8.31695.55-75.33Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-16Buy34,0005,147,909$8.44286.96-75.71Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-12Buy16,6005,113,909$8.44140.1-75.71Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-11Buy54,9005,097,309$8.54468.85-76Link
RODDY PETER SCFO2006-05-10Sell10,00016,155$8.585-75.88Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-09Buy94,4005,042,409$8.54806.18-76Link
BARBIER REMIPresident and CEO, 10% Owner2006-05-08Sell35,0008,000,200$8.63302.05-76.25Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-05-01Buy4,154177,275$4.4318.4-53.72Link
RODDY PETER SCFO2006-05-01Buy2,18416,155$4.439.68-53.72Link
RODDY PETER SCFO2006-04-10Sell10,00013,971$9.2792.7-77.89Link
BARBIER REMIPresident and CEO, 10% Owner2006-04-03Sell35,0008,035,200$10.61371.35-80.68Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-03-15Sell25,000174,121$10.86271.5-81.12Link
RODDY PETER SCFO2006-03-10Sell10,00013,971$10.74107.4-80.91Link
BARBIER REMIPresident and CEO, 10% Owner2006-03-06Sell35,0008,070,200$10.56369.6-80.59Link
O DONNELL MICHAEL JDirector2006-02-23Sell19,05439,885$11.22213.79-81.73Link
BARBIER REMICEO, 10% Owner2006-02-07Sell2,0008,116,200$8.7817.56-76.65Link
BARBIER REMICEO, 10% Owner2006-02-07Sell33,0008,118,200$9.09299.97-77.45Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-30Buy32,5524,948,009$6.79221.03-69.81Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-29Buy31,0894,915,457$6.79211.09-69.81Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-20Buy45,8124,884,368$6.79311.06-69.81Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-16Buy4,0004,838,556$6.7827.12-69.76Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-15Buy29,8804,834,556$6.78202.59-69.76Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-09Buy4,4104,804,676$6.1327.03-66.56Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-08Buy12,9004,800,266$6.1379.08-66.56Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-04Buy38,4564,787,366$5.97229.58-65.66Link
RODDY PETER SVice President & CFO2005-11-01Buy1,44416,971$4.436.4-53.72Link
FRIEDMANN NADAVChief Operating & Medical Off.2005-11-01Buy4,121199,121$4.4318.26-53.72Link
FRIEDMANN NADAVCOO2005-10-28Buy25,000195,000$2502.5Link
FRIEDMANN NADAVCOO2005-10-10Buy15,000170,000$2302.5Link
FRIEDMANN NADAVCOO2005-10-05Buy10,000155,000$2202.5Link
RODDY PETER SCFO2004-10-29Buy2,99315,527$2.748.2-25.18Link
RODDY PETER SVice President & CFO2004-04-30Buy12,5340$2.7434.34-25.18Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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