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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Remi BarbierN/A4,369,7319.47%2014-07-14
Sanford R. RobertsonN/A438,3620.95%2014-03-21
Nadav Friedmann,M.D.N/A359,8930.78%2014-11-18
Peter S. RoddyN/A103,0930.22%2014-07-14
Grant L. Schoenhard,PhDN/A78,5510.17%2014-07-11
Michael J. O'Donnell,Esq.N/A32,118less than 0.1%2014-03-21
Robert Z. Gussin,PhDN/A27,360less than 0.1%2014-05-27

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
ROBERTSON SANFORDDirector2013-11-06Buy50,000369,727$3.73186.5-36.46369,727 (Direct)
FRIEDMANN NADAVCOO2011-10-18Sell25,000259,255$4.44111-46.62259,255 (Direct)
FRIEDMANN NADAVCOO2011-10-04Sell25,000284,255$4.81120.25-50.73284,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-10-04Sell382,0004,263,076$4.591753.38-48.374,263,076 (Direct)
FRIEDMANN NADAVCOO2011-09-15Sell25,000309,255$4.89122.25-51.53309,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-08-08Sell44,4174,645,076$4.2186.55-43.574,645,076 (Direct)
BARBIER REMICEO, Chairman of the Board, 10% Owner
(Click for the stocks that their CEOs have bought)
2011-08-08Buy5,0005,948,053$4.2221.1-43.845,948,053 (Direct)
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-10-04Sell50,0005,929,587$6.2310-61.77Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-07Sell28,5975,979,587$5.69162.72-58.35Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-02Sell21,4036,008,184$5.81124.35-59.21Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-09Sell19,4696,029,587$5.64109.81-57.98Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-04Sell22,3916,049,056$5.71127.85-58.49Link
SCHOENHARD GRANTChief Scientific Officer2010-07-16Sell1,50048,157$5.548.31-57.22Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-07Sell27,2436,071,447$5.35145.75-55.7Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-02Sell22,7576,098,690$5.42123.34-56.27Link
SCHOENHARD GRANTChief Scientific Officer2010-06-16Sell1,50048,187$5.458.18-56.51Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-06-03Sell50,0006,121,447$5.53276.5-57.14Link
SCHOENHARD GRANTChief Scientific Officer2010-05-27Sell10,97948,187$5.7463.02-58.71Link
SCHOENHARD GRANTChief Scientific Officer2010-05-19Sell2,48648,187$5.7714.34-58.93Link
SCHOENHARD GRANTChief Scientific Officer2010-05-18Sell13,03548,187$5.7775.21-58.93Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-06Sell6,5766,171,447$5.6136.89-57.75Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-05Sell43,4246,178,023$5.91256.64-59.9Link
FRIEDMANN NADAVCOO2010-05-04Sell15,000275,951$5.9589.25-60.17Link
SCHOENHARD GRANTChief Scientific Officer2010-04-16Sell26,50048,187$6.29166.69-62.32Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-04-07Sell5,8006,221,447$6.2336.13-61.96Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-04-06Sell32,2006,227,247$6.25201.25-62.08Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-04-01Sell12,0006,259,447$6.1673.92-61.53Link
FRIEDMANN NADAVCOO2010-04-01Sell15,000287,195$6.1792.55-61.59Link
SCHOENHARD GRANTChief Scientific Officer2010-03-16Sell35,00048,187$6.13214.55-61.34Link
O DONNELL MICHAEL JDirector2010-03-11Sell25,0005,775$6.14153.5-61.4Link
BARBIER REMICEO and Chair of Board, 10% Owner2010-03-03Sell5,4436,271,447$6.1333.37-61.34Link
BARBIER REMICEO and Chair of the Board, 10% Owner2010-03-02Sell44,5576,276,890$6.07270.46-60.96Link
BARBIER REMICEO, President, Chairman of Bd, 10% Owner2010-02-02Sell50,0006,350,247$5.32266-55.45Link
BARBIER REMICEO, Chairman of Board, 10% Owner2010-01-06Sell50,0006,372,475$5.39269.5-56.03Link
FRIEDMANN NADAVCOO2009-11-16Sell15,000302,258$575-52.6Link
BARBIER REMICEO,, 10% Owner2009-11-05Sell50,0006,472,475$4.83241.5-50.93Link
BARBIER REMICEO, 10% Owner2009-10-02Sell20,0006,552,475$5.1102-53.53Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-09-29Sell3,076,9153,230,204$4.9815323.04-52.41Link
BARBIER REMICEO, 10% Owner2009-09-11Sell23,2006,599,275$5.23121.34-54.68Link
RODDY PETER SCFO2009-08-31Sell40,00054,783$5.08203.2-53.35Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-08-07Sell1,663,0006,307,119$3.966585.48-40.15Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-14Sell90,7787,970,119$4.23383.99-43.97
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.44-48.25
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.44-48.25
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-15Sell195,9215,810,453$5.07993.32-53.25
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-15Sell285,7038,428,897$5.071448.51-53.25
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-10Sell310,5216,006,374$5.271636.45-55.03
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-10Sell461,2748,714,600$5.272430.91-55.03
BARBIER REMIPresident and CEO, 10% Owner2009-06-05Sell50,0006,644,075$5.26263-54.94
BARBIER REMICEO and Chairman of the Board, 10% Owner2009-05-16Sell26,8006,572,475$5.23140.16-54.68Link
RODDY PETER SVice President & CFO2009-05-01Buy3,37454,783$3.7712.72-37.14
FRIEDMANN NADAVCOO2009-05-01Buy3,374317,258$3.7712.72-37.14
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-04-06Sell900,0009,175,874$4.153735-42.89
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-04-06Sell621,8606,316,895$4.152580.72-42.89
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-03-02Sell1,000,00010,075,874$3.583580-33.8
BARBIER REMIPresident and CEO, Director, 10% Owner2009-02-03Sell50,0006,694,075$6.46323-63.31
BARBIER REMIPresident and CEO, Director, 10% Owner2009-01-05Sell50,0006,744,075$6.13306.5-61.34
BARBIER REMIPresident and CEO, Director, 10% Owner2008-12-02Sell50,0006,794,075$8.58429-72.38
BARBIER REMIPresident and CEO, Director, 10% Owner2008-11-04Sell50,0006,844,075$8.81440.5-73.1
BARBIER REMIPresident and CEO, Director, 10% Owner2008-10-02Sell50,0006,896,575$9.76488-75.72
BARBIER REMIPresident and CEO, Director, 10% Owner2008-09-03Sell50,0006,850,200$9.41470.5-74.81
BARBIER REMIPresident and CEO, Director, 10% Owner2008-08-04Sell50,0006,775,200$8.34417-71.58
BARBIER REMIPresident and CEO, Director, 10% Owner2008-07-02Sell50,0006,825,200$7.71385.5-69.26
BARBIER REMIPresident and CEO, Director, 10% Owner2008-06-03Sell50,0006,875,200$8.04402-70.52
BARBIER REMIPresident and CEO, Director, 10% Owner2008-05-02Sell50,0006,925,200$7.38369-67.89
RODDY PETER SVice President and CFO2008-05-01Buy3,26825,709$6.320.59-62.38
FRIEDMANN NADAVChief Operating & Med. Officer, Director2008-05-01Buy3,267208,572$6.320.58-62.38
BARBIER REMIPresident and CEO, Director, 10% Owner2008-04-02Sell50,0006,975,200$8.59429.5-72.41
BARBIER REMIPresident and CEO, Director, 10% Owner2008-03-04Sell50,0007,041,200$8.16408-70.96
EASTBOURNE CAPITAL MANAGEMENT10% Owner2008-02-29Buy174,70011,075,874$9.111591.52-73.98
BARBIER REMIPresident and CEO, Director, 10% Owner2008-02-04Sell50,0007,091,200$8.88444-73.31
BARBIER REMIPresident and CEO, Director, 10% Owner2008-01-03Sell50,0007,141,200$10.19509.5-76.74
BARBIER REMIPresident and CEO, Director, 10% Owner2007-12-04Sell50,0007,191,200$10.26513-76.9
BARBIER REMIPresident and CEO, Director, 10% Owner2007-11-02Sell50,0007,241,200$10.91545.5-78.28
BARBIER REMIPresident and CEO2007-10-02Sell50,0007,291,200$9.7485-75.57
BARBIER REMIPresident and CEO2007-09-05Sell50,0007,341,200$9.53476.5-75.13
BARBIER REMIPresident and CEO2007-08-02Sell50,0007,391,200$8.45422.5-71.95
BARBIER REMIPresident and CEO2007-07-03Sell50,0001,441,200$8.91445.5-73.4
BARBIER REMIPresident and CEO2007-07-03Sell50,0007,441,200$8.91445.5-73.4
RODDY PETER SVice President and CFO2007-06-11Sell10,00021,415$8.1781.7-70.99
BARBIER REMIPresident and CEO2007-06-04Sell50,0007,491,200$8.39419.5-71.75
BARBIER REMIPresident and CEO2007-05-02Sell50,0007,541,200$8.2410-71.1
RODDY PETER SCFO2007-04-10Sell10,00016,757$7.9779.7-70.26
BARBIER REMIPresident and CEO2007-04-03Sell50,0007,591,200$7.89394.5-69.96
RODDY PETER SChief Financial Officer2007-03-12Sell10,00016,757$7.3973.9-67.93
BARBIER REMIPresident and CEO2007-03-02Sell50,0007,641,200$7.67383.5-69.1
FRIEDMANN NADAVChief Operating & Med. Officer2007-02-28Sell4,000150,596$7.8531.4-69.81
BARBIER REMIPresident and CEO2007-02-16Sell50,0007,705,200$8.41420.5-71.82
RODDY PETER SChief Financial Officer2007-02-12Sell10,00016,757$8.5485.4-72.25
FRIEDMANN NADAVChief Operating & Med. Officer2007-01-31Sell4,000154,596$8.935.6-73.37
RODDY PETER SChief Financial Officer2007-01-10Sell10,00016,757$8.686-72.44
FRIEDMANN NADAVChief Operating & Med. Officer2006-12-29Sell4,000158,596$9.1336.52-74.04
RODDY PETER SChief Financial Officer2006-12-11Sell10,00016,757$8.5585.5-72.28
BARBIER REMIPresident and CEO2006-12-04Sell35,0007,755,200$8.55299.25-72.28
FRIEDMANN NADAVChief Operating & Med. Officer2006-11-30Sell4,000162,596$8.5934.36-72.41
RODDY PETER SChief Financial Officer2006-11-10Sell10,00020,757$8.0180.1-70.41
BARBIER REMIPresident and CEO2006-11-06Sell35,0007,790,200$8.28289.8-71.38
FRIEDMANN NADAVOperating & Med. Officer2006-10-31Sell4,000165,275$8.3233.28-71.51
RODDY PETER SChief Financial Officer2006-10-10Sell10,00016,155$8.4184.1-71.82
BARBIER REMIPresident and CEO2006-10-09Sell35,0007,825,200$8.56299.6-72.31
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-19Buy2,9005,666,732$7.8822.85-69.92Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-14Buy7005,663,832$7.885.52-69.92Link
RODDY PETER SCFO2006-09-11Sell10,00016,155$7.8678.6-69.85Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-11Buy4,0645,663,132$7.8832.02-69.92Link
BARBIER REMIPresident and CEO, 10% Owner2006-09-05Sell35,0007,860,200$8.39293.65-71.75Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-08-31Sell4,000173,275$8.3733.48-71.68Link
RODDY PETER SCFO2006-08-10Sell10,00016,155$8.8388.3-73.16Link
BARBIER REMIPresident & CEO, 10% Owner2006-08-07Sell35,0007,895,200$8.56299.6-72.31Link
RODDY PETER SCFO2006-07-10Sell10,00016,155$8.3383.3-71.55Link
BARBIER REMIPresident and CEO, 10% Owner2006-07-03Sell35,0007,930,200$8.38293.3-71.72Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-19Buy81,4005,659,068$7.79634.11-69.58Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-16Buy114,3005,577,668$7.86898.4-69.85Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-14Buy26,3005,463,368$7.93208.56-70.11Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-13Buy72,5175,437,068$8.01580.86-70.41Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-12Buy2,0005,364,551$8.0416.08-70.52Link
RODDY PETER SCFO2006-06-12Sell10,00016,155$8.1381.3-70.85Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-08Buy42,6005,362,551$8.15347.19-70.92Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-06Buy3,8005,319,951$8.1931.12-71.06Link
BARBIER REMIPresident and CEO, 10% Owner2006-06-05Sell35,0007,965,200$8.68303.8-72.7Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-25Buy3,0655,316,151$8.1925.1-71.06Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-24Buy37,4005,313,086$8.19306.31-71.06Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-22Buy21,7005,275,686$8.19177.72-71.06Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-19Buy1,4005,253,986$8.1911.47-71.06Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-18Buy20,9775,252,586$8.19171.8-71.06Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-17Buy83,7005,231,609$8.31695.55-71.48Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-16Buy34,0005,147,909$8.44286.96-71.92Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-12Buy16,6005,113,909$8.44140.1-71.92Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-11Buy54,9005,097,309$8.54468.85-72.25Link
RODDY PETER SCFO2006-05-10Sell10,00016,155$8.585-72.12Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-09Buy94,4005,042,409$8.54806.18-72.25Link
BARBIER REMIPresident and CEO, 10% Owner2006-05-08Sell35,0008,000,200$8.63302.05-72.54Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-05-01Buy4,154177,275$4.4318.4-46.5Link
RODDY PETER SCFO2006-05-01Buy2,18416,155$4.439.68-46.5Link
RODDY PETER SCFO2006-04-10Sell10,00013,971$9.2792.7-74.43Link
BARBIER REMIPresident and CEO, 10% Owner2006-04-03Sell35,0008,035,200$10.61371.35-77.66Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-03-15Sell25,000174,121$10.86271.5-78.18Link
RODDY PETER SCFO2006-03-10Sell10,00013,971$10.74107.4-77.93Link
BARBIER REMIPresident and CEO, 10% Owner2006-03-06Sell35,0008,070,200$10.56369.6-77.56Link
O DONNELL MICHAEL JDirector2006-02-23Sell19,05439,885$11.22213.79-78.88Link
BARBIER REMICEO, 10% Owner2006-02-07Sell2,0008,116,200$8.7817.56-73.01Link
BARBIER REMICEO, 10% Owner2006-02-07Sell33,0008,118,200$9.09299.97-73.93Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-30Buy32,5524,948,009$6.79221.03-65.1Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-29Buy31,0894,915,457$6.79211.09-65.1Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-20Buy45,8124,884,368$6.79311.06-65.1Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-16Buy4,0004,838,556$6.7827.12-65.04Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-15Buy29,8804,834,556$6.78202.59-65.04Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-09Buy4,4104,804,676$6.1327.03-61.34Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-08Buy12,9004,800,266$6.1379.08-61.34Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-04Buy38,4564,787,366$5.97229.58-60.3Link
RODDY PETER SVice President & CFO2005-11-01Buy1,44416,971$4.436.4-46.5Link
FRIEDMANN NADAVChief Operating & Medical Off.2005-11-01Buy4,121199,121$4.4318.26-46.5Link
FRIEDMANN NADAVCOO2005-10-28Buy25,000195,000$25018.5Link
FRIEDMANN NADAVCOO2005-10-10Buy15,000170,000$23018.5Link
FRIEDMANN NADAVCOO2005-10-05Buy10,000155,000$22018.5Link
RODDY PETER SCFO2004-10-29Buy2,99315,527$2.748.2-13.5Link
RODDY PETER SVice President & CFO2004-04-30Buy12,5340$2.7434.34-13.5Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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