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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Remi BarbierN/A4,369,7319.47%2014-07-14
Sanford R. RobertsonN/A438,3620.95%2014-03-21
Nadav Friedmann,M.D.N/A359,8930.78%2014-11-18
Peter S. RoddyN/A103,0930.22%2014-07-14
Grant L. Schoenhard,PhDN/A78,5510.17%2014-07-11
Michael J. O'Donnell,Esq.N/A32,118less than 0.1%2014-03-21
Robert Z. Gussin,PhDN/A27,360less than 0.1%2014-05-27

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
ROBERTSON SANFORDDirector2013-11-06Buy50,000369,727$3.73186.5-37.8369,727 (Direct)
FRIEDMANN NADAVCOO2011-10-18Sell25,000259,255$4.44111-47.75259,255 (Direct)
FRIEDMANN NADAVCOO2011-10-04Sell25,000284,255$4.81120.3-51.77284,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-10-04Sell382,0004,263,076$4.591753.4-49.464,263,076 (Direct)
FRIEDMANN NADAVCOO2011-09-15Sell25,000309,255$4.89122.3-52.56309,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-08-08Sell44,4174,645,076$4.2186.6-44.764,645,076 (Direct)
BARBIER REMICEO, Chairman of the Board, 10% Owner
(Click for the stocks that their CEOs have bought)
2011-08-08Buy5,0005,948,053$4.2221.1-45.025,948,053 (Direct)
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-10-04Sell50,0005,929,587$6.2310-62.58Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-07Sell28,5975,979,587$5.69162.7-59.23Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-02Sell21,4036,008,184$5.81124.4-60.07Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-09Sell19,4696,029,587$5.64109.8-58.87Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-04Sell22,3916,049,056$5.71127.9-59.37Link
SCHOENHARD GRANTChief Scientific Officer2010-07-16Sell1,50048,157$5.548.3-58.12Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-07Sell27,2436,071,447$5.35145.8-56.64Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-02Sell22,7576,098,690$5.42123.3-57.2Link
SCHOENHARD GRANTChief Scientific Officer2010-06-16Sell1,50048,187$5.458.2-57.43Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-06-03Sell50,0006,121,447$5.53276.5-58.05Link
SCHOENHARD GRANTChief Scientific Officer2010-05-27Sell10,97948,187$5.7463-59.58Link
SCHOENHARD GRANTChief Scientific Officer2010-05-19Sell2,48648,187$5.7714.3-59.79Link
SCHOENHARD GRANTChief Scientific Officer2010-05-18Sell13,03548,187$5.7775.2-59.79Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-06Sell6,5766,171,447$5.6136.9-58.65Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-05Sell43,4246,178,023$5.91256.6-60.74Link
FRIEDMANN NADAVCOO2010-05-04Sell15,000275,951$5.9589.3-61.01Link
SCHOENHARD GRANTChief Scientific Officer2010-04-16Sell26,50048,187$6.29166.7-63.12Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-04-07Sell5,8006,221,447$6.2336.1-62.76Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-04-06Sell32,2006,227,247$6.25201.3-62.88Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-04-01Sell12,0006,259,447$6.1673.9-62.34Link
FRIEDMANN NADAVCOO2010-04-01Sell15,000287,195$6.1792.6-62.4Link
SCHOENHARD GRANTChief Scientific Officer2010-03-16Sell35,00048,187$6.13214.6-62.15Link
O DONNELL MICHAEL JDirector2010-03-11Sell25,0005,775$6.14153.5-62.21Link
BARBIER REMICEO and Chair of Board, 10% Owner2010-03-03Sell5,4436,271,447$6.1333.4-62.15Link
BARBIER REMICEO and Chair of the Board, 10% Owner2010-03-02Sell44,5576,276,890$6.07270.5-61.78Link
BARBIER REMICEO, President, Chairman of Bd, 10% Owner2010-02-02Sell50,0006,350,247$5.32266-56.39Link
BARBIER REMICEO, Chairman of Board, 10% Owner2010-01-06Sell50,0006,372,475$5.39269.5-56.96Link
FRIEDMANN NADAVCOO2009-11-16Sell15,000302,258$575-53.6Link
BARBIER REMICEO,, 10% Owner2009-11-05Sell50,0006,472,475$4.83241.5-51.97Link
BARBIER REMICEO, 10% Owner2009-10-02Sell20,0006,552,475$5.1102-54.51Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-09-29Sell3,076,9153,230,204$4.9815323-53.41Link
BARBIER REMICEO, 10% Owner2009-09-11Sell23,2006,599,275$5.23121.3-55.64Link
RODDY PETER SCFO2009-08-31Sell40,00054,783$5.08203.2-54.33Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-08-07Sell1,663,0006,307,119$3.966585.5-41.41Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-14Sell90,7787,970,119$4.23384-45.15
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.4-49.34
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.4-49.34
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-15Sell195,9215,810,453$5.07993.3-54.24
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-15Sell285,7038,428,897$5.071448.5-54.24
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-10Sell310,5216,006,374$5.271636.4-55.98
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-10Sell461,2748,714,600$5.272430.9-55.98
BARBIER REMIPresident and CEO, 10% Owner2009-06-05Sell50,0006,644,075$5.26263-55.89
BARBIER REMICEO and Chairman of the Board, 10% Owner2009-05-16Sell26,8006,572,475$5.23140.2-55.64Link
RODDY PETER SVice President & CFO2009-05-01Buy3,37454,783$3.7712.7-38.46
FRIEDMANN NADAVCOO2009-05-01Buy3,374317,258$3.7712.7-38.46
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-04-06Sell900,0009,175,874$4.153735-44.1
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-04-06Sell621,8606,316,895$4.152580.7-44.1
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-03-02Sell1,000,00010,075,874$3.583580-35.2
BARBIER REMIPresident and CEO, Director, 10% Owner2009-02-03Sell50,0006,694,075$6.46323-64.09
BARBIER REMIPresident and CEO, Director, 10% Owner2009-01-05Sell50,0006,744,075$6.13306.5-62.15
BARBIER REMIPresident and CEO, Director, 10% Owner2008-12-02Sell50,0006,794,075$8.58429-72.96
BARBIER REMIPresident and CEO, Director, 10% Owner2008-11-04Sell50,0006,844,075$8.81440.5-73.67
BARBIER REMIPresident and CEO, Director, 10% Owner2008-10-02Sell50,0006,896,575$9.76488-76.23
BARBIER REMIPresident and CEO, Director, 10% Owner2008-09-03Sell50,0006,850,200$9.41470.5-75.35
BARBIER REMIPresident and CEO, Director, 10% Owner2008-08-04Sell50,0006,775,200$8.34417-72.18
BARBIER REMIPresident and CEO, Director, 10% Owner2008-07-02Sell50,0006,825,200$7.71385.5-69.91
BARBIER REMIPresident and CEO, Director, 10% Owner2008-06-03Sell50,0006,875,200$8.04402-71.14
BARBIER REMIPresident and CEO, Director, 10% Owner2008-05-02Sell50,0006,925,200$7.38369-68.56
RODDY PETER SVice President and CFO2008-05-01Buy3,26825,709$6.320.6-63.17
FRIEDMANN NADAVChief Operating & Med. Officer, Director2008-05-01Buy3,267208,572$6.320.6-63.17
BARBIER REMIPresident and CEO, Director, 10% Owner2008-04-02Sell50,0006,975,200$8.59429.5-72.99
BARBIER REMIPresident and CEO, Director, 10% Owner2008-03-04Sell50,0007,041,200$8.16408-71.57
EASTBOURNE CAPITAL MANAGEMENT10% Owner2008-02-29Buy174,70011,075,874$9.111591.5-74.53
BARBIER REMIPresident and CEO, Director, 10% Owner2008-02-04Sell50,0007,091,200$8.88444-73.87
BARBIER REMIPresident and CEO, Director, 10% Owner2008-01-03Sell50,0007,141,200$10.19509.5-77.23
BARBIER REMIPresident and CEO, Director, 10% Owner2007-12-04Sell50,0007,191,200$10.26513-77.39
BARBIER REMIPresident and CEO, Director, 10% Owner2007-11-02Sell50,0007,241,200$10.91545.5-78.74
BARBIER REMIPresident and CEO2007-10-02Sell50,0007,291,200$9.7485-76.08
BARBIER REMIPresident and CEO2007-09-05Sell50,0007,341,200$9.53476.5-75.66
BARBIER REMIPresident and CEO2007-08-02Sell50,0007,391,200$8.45422.5-72.54
BARBIER REMIPresident and CEO2007-07-03Sell50,0001,441,200$8.91445.5-73.96
BARBIER REMIPresident and CEO2007-07-03Sell50,0007,441,200$8.91445.5-73.96
RODDY PETER SVice President and CFO2007-06-11Sell10,00021,415$8.1781.7-71.6
BARBIER REMIPresident and CEO2007-06-04Sell50,0007,491,200$8.39419.5-72.35
BARBIER REMIPresident and CEO2007-05-02Sell50,0007,541,200$8.2410-71.71
RODDY PETER SCFO2007-04-10Sell10,00016,757$7.9779.7-70.89
BARBIER REMIPresident and CEO2007-04-03Sell50,0007,591,200$7.89394.5-70.6
RODDY PETER SChief Financial Officer2007-03-12Sell10,00016,757$7.3973.9-68.61
BARBIER REMIPresident and CEO2007-03-02Sell50,0007,641,200$7.67383.5-69.75
FRIEDMANN NADAVChief Operating & Med. Officer2007-02-28Sell4,000150,596$7.8531.4-70.45
BARBIER REMIPresident and CEO2007-02-16Sell50,0007,705,200$8.41420.5-72.41
RODDY PETER SChief Financial Officer2007-02-12Sell10,00016,757$8.5485.4-72.83
FRIEDMANN NADAVChief Operating & Med. Officer2007-01-31Sell4,000154,596$8.935.6-73.93
RODDY PETER SChief Financial Officer2007-01-10Sell10,00016,757$8.686-73.02
FRIEDMANN NADAVChief Operating & Med. Officer2006-12-29Sell4,000158,596$9.1336.5-74.59
RODDY PETER SChief Financial Officer2006-12-11Sell10,00016,757$8.5585.5-72.87
BARBIER REMIPresident and CEO2006-12-04Sell35,0007,755,200$8.55299.3-72.87
FRIEDMANN NADAVChief Operating & Med. Officer2006-11-30Sell4,000162,596$8.5934.4-72.99
RODDY PETER SChief Financial Officer2006-11-10Sell10,00020,757$8.0180.1-71.04
BARBIER REMIPresident and CEO2006-11-06Sell35,0007,790,200$8.28289.8-71.98
FRIEDMANN NADAVOperating & Med. Officer2006-10-31Sell4,000165,275$8.3233.3-72.12
RODDY PETER SChief Financial Officer2006-10-10Sell10,00016,155$8.4184.1-72.41
BARBIER REMIPresident and CEO2006-10-09Sell35,0007,825,200$8.56299.6-72.9
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-19Buy2,9005,666,732$7.8822.9-70.56Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-14Buy7005,663,832$7.885.5-70.56Link
RODDY PETER SCFO2006-09-11Sell10,00016,155$7.8678.6-70.48Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-11Buy4,0645,663,132$7.8832-70.56Link
BARBIER REMIPresident and CEO, 10% Owner2006-09-05Sell35,0007,860,200$8.39293.7-72.35Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-08-31Sell4,000173,275$8.3733.5-72.28Link
RODDY PETER SCFO2006-08-10Sell10,00016,155$8.8388.3-73.73Link
BARBIER REMIPresident & CEO, 10% Owner2006-08-07Sell35,0007,895,200$8.56299.6-72.9Link
RODDY PETER SCFO2006-07-10Sell10,00016,155$8.3383.3-72.15Link
BARBIER REMIPresident and CEO, 10% Owner2006-07-03Sell35,0007,930,200$8.38293.3-72.32Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-19Buy81,4005,659,068$7.79634.1-70.22Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-16Buy114,3005,577,668$7.86898.4-70.48Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-14Buy26,3005,463,368$7.93208.6-70.74Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-13Buy72,5175,437,068$8.01580.9-71.04Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-12Buy2,0005,364,551$8.0416.1-71.14Link
RODDY PETER SCFO2006-06-12Sell10,00016,155$8.1381.3-71.46Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-08Buy42,6005,362,551$8.15347.2-71.53Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-06Buy3,8005,319,951$8.1931.1-71.67Link
BARBIER REMIPresident and CEO, 10% Owner2006-06-05Sell35,0007,965,200$8.68303.8-73.27Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-25Buy3,0655,316,151$8.1925.1-71.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-24Buy37,4005,313,086$8.19306.3-71.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-22Buy21,7005,275,686$8.19177.7-71.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-19Buy1,4005,253,986$8.1911.5-71.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-18Buy20,9775,252,586$8.19171.8-71.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-17Buy83,7005,231,609$8.31695.5-72.08Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-16Buy34,0005,147,909$8.44287-72.51Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-12Buy16,6005,113,909$8.44140.1-72.51Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-11Buy54,9005,097,309$8.54468.8-72.83Link
RODDY PETER SCFO2006-05-10Sell10,00016,155$8.585-72.71Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-09Buy94,4005,042,409$8.54806.2-72.83Link
BARBIER REMIPresident and CEO, 10% Owner2006-05-08Sell35,0008,000,200$8.63302.1-73.12Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-05-01Buy4,154177,275$4.4318.4-47.63Link
RODDY PETER SCFO2006-05-01Buy2,18416,155$4.439.7-47.63Link
RODDY PETER SCFO2006-04-10Sell10,00013,971$9.2792.7-74.97Link
BARBIER REMIPresident and CEO, 10% Owner2006-04-03Sell35,0008,035,200$10.61371.4-78.13Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-03-15Sell25,000174,121$10.86271.5-78.64Link
RODDY PETER SCFO2006-03-10Sell10,00013,971$10.74107.4-78.4Link
BARBIER REMIPresident and CEO, 10% Owner2006-03-06Sell35,0008,070,200$10.56369.6-78.03Link
O DONNELL MICHAEL JDirector2006-02-23Sell19,05439,885$11.22213.8-79.32Link
BARBIER REMICEO, 10% Owner2006-02-07Sell2,0008,116,200$8.7817.6-73.58Link
BARBIER REMICEO, 10% Owner2006-02-07Sell33,0008,118,200$9.09300-74.48Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-30Buy32,5524,948,009$6.79221-65.83Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-29Buy31,0894,915,457$6.79211.1-65.83Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-20Buy45,8124,884,368$6.79311.1-65.83Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-16Buy4,0004,838,556$6.7827.1-65.78Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-15Buy29,8804,834,556$6.78202.6-65.78Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-09Buy4,4104,804,676$6.1327-62.15Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-08Buy12,9004,800,266$6.1379.1-62.15Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-04Buy38,4564,787,366$5.97229.6-61.14Link
RODDY PETER SVice President & CFO2005-11-01Buy1,44416,971$4.436.4-47.63Link
FRIEDMANN NADAVChief Operating & Medical Off.2005-11-01Buy4,121199,121$4.4318.3-47.63Link
FRIEDMANN NADAVCOO2005-10-28Buy25,000195,000$25016Link
FRIEDMANN NADAVCOO2005-10-10Buy15,000170,000$23016Link
FRIEDMANN NADAVCOO2005-10-05Buy10,000155,000$22016Link
RODDY PETER SCFO2004-10-29Buy2,99315,527$2.748.2-15.33Link
RODDY PETER SVice President & CFO2004-04-30Buy12,5340$2.7434.3-15.33Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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