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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Remi BarbierN/A4,369,7319.47%2014-07-14
Sanford R. RobertsonN/A438,3620.95%2014-03-21
Nadav Friedmann,M.D.N/A359,8930.78%2014-11-18
Peter S. RoddyN/A103,0930.22%2014-07-14
Grant L. Schoenhard,PhDN/A78,5510.17%2014-07-11
Michael J. O'Donnell,Esq.N/A32,118less than 0.1%2014-03-21
Robert Z. Gussin,PhDN/A27,360less than 0.1%2014-05-27

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
ROBERTSON SANFORDDirector2013-11-06Buy50,000369,727$3.73186.5-26.81369,727 (Direct)
FRIEDMANN NADAVCOO2011-10-18Sell25,000259,255$4.44111-38.51259,255 (Direct)
FRIEDMANN NADAVCOO2011-10-04Sell25,000284,255$4.81120.25-43.24284,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-10-04Sell382,0004,263,076$4.591753.38-40.524,263,076 (Direct)
FRIEDMANN NADAVCOO2011-09-15Sell25,000309,255$4.89122.25-44.17309,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-08-08Sell44,4174,645,076$4.2186.55-354,645,076 (Direct)
BARBIER REMICEO, Chairman of the Board, 10% Owner
(Click for the stocks that their CEOs have bought)
2011-08-08Buy5,0005,948,053$4.2221.1-35.315,948,053 (Direct)
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-10-04Sell50,0005,929,587$6.2310-55.97Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-07Sell28,5975,979,587$5.69162.72-52.02Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-02Sell21,4036,008,184$5.81124.35-53.01Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-09Sell19,4696,029,587$5.64109.81-51.6Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-04Sell22,3916,049,056$5.71127.85-52.19Link
SCHOENHARD GRANTChief Scientific Officer2010-07-16Sell1,50048,157$5.548.31-50.72Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-07Sell27,2436,071,447$5.35145.75-48.97Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-02Sell22,7576,098,690$5.42123.34-49.63Link
SCHOENHARD GRANTChief Scientific Officer2010-06-16Sell1,50048,187$5.458.18-49.91Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-06-03Sell50,0006,121,447$5.53276.5-50.63Link
SCHOENHARD GRANTChief Scientific Officer2010-05-27Sell10,97948,187$5.7463.02-52.44Link
SCHOENHARD GRANTChief Scientific Officer2010-05-19Sell2,48648,187$5.7714.34-52.69Link
SCHOENHARD GRANTChief Scientific Officer2010-05-18Sell13,03548,187$5.7775.21-52.69Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-06Sell6,5766,171,447$5.6136.89-51.34Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-05Sell43,4246,178,023$5.91256.64-53.81Link
FRIEDMANN NADAVCOO2010-05-04Sell15,000275,951$5.9589.25-54.12Link
SCHOENHARD GRANTChief Scientific Officer2010-04-16Sell26,50048,187$6.29166.69-56.6Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-04-07Sell5,8006,221,447$6.2336.13-56.18Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-04-06Sell32,2006,227,247$6.25201.25-56.32Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-04-01Sell12,0006,259,447$6.1673.92-55.68Link
FRIEDMANN NADAVCOO2010-04-01Sell15,000287,195$6.1792.55-55.75Link
SCHOENHARD GRANTChief Scientific Officer2010-03-16Sell35,00048,187$6.13214.55-55.46Link
O DONNELL MICHAEL JDirector2010-03-11Sell25,0005,775$6.14153.5-55.54Link
BARBIER REMICEO and Chair of Board, 10% Owner2010-03-03Sell5,4436,271,447$6.1333.37-55.46Link
BARBIER REMICEO and Chair of the Board, 10% Owner2010-03-02Sell44,5576,276,890$6.07270.46-55.02Link
BARBIER REMICEO, President, Chairman of Bd, 10% Owner2010-02-02Sell50,0006,350,247$5.32266-48.68Link
BARBIER REMICEO, Chairman of Board, 10% Owner2010-01-06Sell50,0006,372,475$5.39269.5-49.35Link
FRIEDMANN NADAVCOO2009-11-16Sell15,000302,258$575-45.4Link
BARBIER REMICEO,, 10% Owner2009-11-05Sell50,0006,472,475$4.83241.5-43.48Link
BARBIER REMICEO, 10% Owner2009-10-02Sell20,0006,552,475$5.1102-46.47Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-09-29Sell3,076,9153,230,204$4.9815323.04-45.18Link
BARBIER REMICEO, 10% Owner2009-09-11Sell23,2006,599,275$5.23121.34-47.8Link
RODDY PETER SCFO2009-08-31Sell40,00054,783$5.08203.2-46.26Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-08-07Sell1,663,0006,307,119$3.966585.48-31.06Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-14Sell90,7787,970,119$4.23383.99-35.46
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.44-40.39
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.44-40.39
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-15Sell195,9215,810,453$5.07993.32-46.15
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-15Sell285,7038,428,897$5.071448.51-46.15
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-10Sell310,5216,006,374$5.271636.45-48.2
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-10Sell461,2748,714,600$5.272430.91-48.2
BARBIER REMIPresident and CEO, 10% Owner2009-06-05Sell50,0006,644,075$5.26263-48.1
BARBIER REMICEO and Chairman of the Board, 10% Owner2009-05-16Sell26,8006,572,475$5.23140.16-47.8Link
RODDY PETER SVice President & CFO2009-05-01Buy3,37454,783$3.7712.72-27.59
FRIEDMANN NADAVCOO2009-05-01Buy3,374317,258$3.7712.72-27.59
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-04-06Sell900,0009,175,874$4.153735-34.22
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-04-06Sell621,8606,316,895$4.152580.72-34.22
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-03-02Sell1,000,00010,075,874$3.583580-23.74
BARBIER REMIPresident and CEO, Director, 10% Owner2009-02-03Sell50,0006,694,075$6.46323-57.74
BARBIER REMIPresident and CEO, Director, 10% Owner2009-01-05Sell50,0006,744,075$6.13306.5-55.46
BARBIER REMIPresident and CEO, Director, 10% Owner2008-12-02Sell50,0006,794,075$8.58429-68.18
BARBIER REMIPresident and CEO, Director, 10% Owner2008-11-04Sell50,0006,844,075$8.81440.5-69.01
BARBIER REMIPresident and CEO, Director, 10% Owner2008-10-02Sell50,0006,896,575$9.76488-72.03
BARBIER REMIPresident and CEO, Director, 10% Owner2008-09-03Sell50,0006,850,200$9.41470.5-70.99
BARBIER REMIPresident and CEO, Director, 10% Owner2008-08-04Sell50,0006,775,200$8.34417-67.27
BARBIER REMIPresident and CEO, Director, 10% Owner2008-07-02Sell50,0006,825,200$7.71385.5-64.59
BARBIER REMIPresident and CEO, Director, 10% Owner2008-06-03Sell50,0006,875,200$8.04402-66.04
BARBIER REMIPresident and CEO, Director, 10% Owner2008-05-02Sell50,0006,925,200$7.38369-63.01
RODDY PETER SVice President and CFO2008-05-01Buy3,26825,709$6.320.59-56.67
FRIEDMANN NADAVChief Operating & Med. Officer, Director2008-05-01Buy3,267208,572$6.320.58-56.67
BARBIER REMIPresident and CEO, Director, 10% Owner2008-04-02Sell50,0006,975,200$8.59429.5-68.22
BARBIER REMIPresident and CEO, Director, 10% Owner2008-03-04Sell50,0007,041,200$8.16408-66.54
EASTBOURNE CAPITAL MANAGEMENT10% Owner2008-02-29Buy174,70011,075,874$9.111591.52-70.03
BARBIER REMIPresident and CEO, Director, 10% Owner2008-02-04Sell50,0007,091,200$8.88444-69.26
BARBIER REMIPresident and CEO, Director, 10% Owner2008-01-03Sell50,0007,141,200$10.19509.5-73.21
BARBIER REMIPresident and CEO, Director, 10% Owner2007-12-04Sell50,0007,191,200$10.26513-73.39
BARBIER REMIPresident and CEO, Director, 10% Owner2007-11-02Sell50,0007,241,200$10.91545.5-74.98
BARBIER REMIPresident and CEO2007-10-02Sell50,0007,291,200$9.7485-71.86
BARBIER REMIPresident and CEO2007-09-05Sell50,0007,341,200$9.53476.5-71.35
BARBIER REMIPresident and CEO2007-08-02Sell50,0007,391,200$8.45422.5-67.69
BARBIER REMIPresident and CEO2007-07-03Sell50,0001,441,200$8.91445.5-69.36
BARBIER REMIPresident and CEO2007-07-03Sell50,0007,441,200$8.91445.5-69.36
RODDY PETER SVice President and CFO2007-06-11Sell10,00021,415$8.1781.7-66.59
BARBIER REMIPresident and CEO2007-06-04Sell50,0007,491,200$8.39419.5-67.46
BARBIER REMIPresident and CEO2007-05-02Sell50,0007,541,200$8.2410-66.71
RODDY PETER SCFO2007-04-10Sell10,00016,757$7.9779.7-65.75
BARBIER REMIPresident and CEO2007-04-03Sell50,0007,591,200$7.89394.5-65.4
RODDY PETER SChief Financial Officer2007-03-12Sell10,00016,757$7.3973.9-63.06
BARBIER REMIPresident and CEO2007-03-02Sell50,0007,641,200$7.67383.5-64.41
FRIEDMANN NADAVChief Operating & Med. Officer2007-02-28Sell4,000150,596$7.8531.4-65.22
BARBIER REMIPresident and CEO2007-02-16Sell50,0007,705,200$8.41420.5-67.54
RODDY PETER SChief Financial Officer2007-02-12Sell10,00016,757$8.5485.4-68.03
FRIEDMANN NADAVChief Operating & Med. Officer2007-01-31Sell4,000154,596$8.935.6-69.33
RODDY PETER SChief Financial Officer2007-01-10Sell10,00016,757$8.686-68.26
FRIEDMANN NADAVChief Operating & Med. Officer2006-12-29Sell4,000158,596$9.1336.52-70.1
RODDY PETER SChief Financial Officer2006-12-11Sell10,00016,757$8.5585.5-68.07
BARBIER REMIPresident and CEO2006-12-04Sell35,0007,755,200$8.55299.25-68.07
FRIEDMANN NADAVChief Operating & Med. Officer2006-11-30Sell4,000162,596$8.5934.36-68.22
RODDY PETER SChief Financial Officer2006-11-10Sell10,00020,757$8.0180.1-65.92
BARBIER REMIPresident and CEO2006-11-06Sell35,0007,790,200$8.28289.8-67.03
FRIEDMANN NADAVOperating & Med. Officer2006-10-31Sell4,000165,275$8.3233.28-67.19
RODDY PETER SChief Financial Officer2006-10-10Sell10,00016,155$8.4184.1-67.54
BARBIER REMIPresident and CEO2006-10-09Sell35,0007,825,200$8.56299.6-68.11
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-19Buy2,9005,666,732$7.8822.85-65.36Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-14Buy7005,663,832$7.885.52-65.36Link
RODDY PETER SCFO2006-09-11Sell10,00016,155$7.8678.6-65.27Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-11Buy4,0645,663,132$7.8832.02-65.36Link
BARBIER REMIPresident and CEO, 10% Owner2006-09-05Sell35,0007,860,200$8.39293.65-67.46Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-08-31Sell4,000173,275$8.3733.48-67.38Link
RODDY PETER SCFO2006-08-10Sell10,00016,155$8.8388.3-69.08Link
BARBIER REMIPresident & CEO, 10% Owner2006-08-07Sell35,0007,895,200$8.56299.6-68.11Link
RODDY PETER SCFO2006-07-10Sell10,00016,155$8.3383.3-67.23Link
BARBIER REMIPresident and CEO, 10% Owner2006-07-03Sell35,0007,930,200$8.38293.3-67.42Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-19Buy81,4005,659,068$7.79634.11-64.96Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-16Buy114,3005,577,668$7.86898.4-65.27Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-14Buy26,3005,463,368$7.93208.56-65.57Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-13Buy72,5175,437,068$8.01580.86-65.92Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-12Buy2,0005,364,551$8.0416.08-66.04Link
RODDY PETER SCFO2006-06-12Sell10,00016,155$8.1381.3-66.42Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-08Buy42,6005,362,551$8.15347.19-66.5Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-06Buy3,8005,319,951$8.1931.12-66.67Link
BARBIER REMIPresident and CEO, 10% Owner2006-06-05Sell35,0007,965,200$8.68303.8-68.55Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-25Buy3,0655,316,151$8.1925.1-66.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-24Buy37,4005,313,086$8.19306.31-66.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-22Buy21,7005,275,686$8.19177.72-66.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-19Buy1,4005,253,986$8.1911.47-66.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-18Buy20,9775,252,586$8.19171.8-66.67Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-17Buy83,7005,231,609$8.31695.55-67.15Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-16Buy34,0005,147,909$8.44286.96-67.65Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-12Buy16,6005,113,909$8.44140.1-67.65Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-11Buy54,9005,097,309$8.54468.85-68.03Link
RODDY PETER SCFO2006-05-10Sell10,00016,155$8.585-67.88Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-09Buy94,4005,042,409$8.54806.18-68.03Link
BARBIER REMIPresident and CEO, 10% Owner2006-05-08Sell35,0008,000,200$8.63302.05-68.37Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-05-01Buy4,154177,275$4.4318.4-38.37Link
RODDY PETER SCFO2006-05-01Buy2,18416,155$4.439.68-38.37Link
RODDY PETER SCFO2006-04-10Sell10,00013,971$9.2792.7-70.55Link
BARBIER REMIPresident and CEO, 10% Owner2006-04-03Sell35,0008,035,200$10.61371.35-74.27Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-03-15Sell25,000174,121$10.86271.5-74.86Link
RODDY PETER SCFO2006-03-10Sell10,00013,971$10.74107.4-74.58Link
BARBIER REMIPresident and CEO, 10% Owner2006-03-06Sell35,0008,070,200$10.56369.6-74.15Link
O DONNELL MICHAEL JDirector2006-02-23Sell19,05439,885$11.22213.79-75.67Link
BARBIER REMICEO, 10% Owner2006-02-07Sell2,0008,116,200$8.7817.56-68.91Link
BARBIER REMICEO, 10% Owner2006-02-07Sell33,0008,118,200$9.09299.97-69.97Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-30Buy32,5524,948,009$6.79221.03-59.79Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-29Buy31,0894,915,457$6.79211.09-59.79Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-20Buy45,8124,884,368$6.79311.06-59.79Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-16Buy4,0004,838,556$6.7827.12-59.73Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-15Buy29,8804,834,556$6.78202.59-59.73Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-09Buy4,4104,804,676$6.1327.03-55.46Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-08Buy12,9004,800,266$6.1379.08-55.46Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-04Buy38,4564,787,366$5.97229.58-54.27Link
RODDY PETER SVice President & CFO2005-11-01Buy1,44416,971$4.436.4-38.37Link
FRIEDMANN NADAVChief Operating & Medical Off.2005-11-01Buy4,121199,121$4.4318.26-38.37Link
FRIEDMANN NADAVCOO2005-10-28Buy25,000195,000$25036.5Link
FRIEDMANN NADAVCOO2005-10-10Buy15,000170,000$23036.5Link
FRIEDMANN NADAVCOO2005-10-05Buy10,000155,000$22036.5Link
RODDY PETER SCFO2004-10-29Buy2,99315,527$2.748.2-0.36Link
RODDY PETER SVice President & CFO2004-04-30Buy12,5340$2.7434.34-0.36Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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