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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Remi BarbierN/A4,369,7319.47%2014-07-14
Sanford R. RobertsonN/A438,3620.95%2014-03-21
Nadav Friedmann,M.D.N/A359,8930.78%2014-11-18
Peter S. RoddyN/A103,0930.22%2014-07-14
Grant L. Schoenhard,PhDN/A78,5510.17%2014-07-11
Michael J. O'Donnell,Esq.N/A32,118less than 0.1%2014-03-21
Robert Z. Gussin,PhDN/A27,360less than 0.1%2014-05-27

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
ROBERTSON SANFORDDirector2013-11-06Buy50,000369,727$3.73186.5-29.22369,727 (Direct)
FRIEDMANN NADAVCOO2011-10-18Sell25,000259,255$4.44111-40.54259,255 (Direct)
FRIEDMANN NADAVCOO2011-10-04Sell25,000284,255$4.81120.25-45.11284,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-10-04Sell382,0004,263,076$4.591753.38-42.484,263,076 (Direct)
FRIEDMANN NADAVCOO2011-09-15Sell25,000309,255$4.89122.25-46.01309,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-08-08Sell44,4174,645,076$4.2186.55-37.144,645,076 (Direct)
BARBIER REMICEO, Chairman of the Board, 10% Owner
(Click for the stocks that their CEOs have bought)
2011-08-08Buy5,0005,948,053$4.2221.1-37.445,948,053 (Direct)
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-10-04Sell50,0005,929,587$6.2310-57.42Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-07Sell28,5975,979,587$5.69162.72-53.6Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-02Sell21,4036,008,184$5.81124.35-54.56Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-09Sell19,4696,029,587$5.64109.81-53.19Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-04Sell22,3916,049,056$5.71127.85-53.77Link
SCHOENHARD GRANTChief Scientific Officer2010-07-16Sell1,50048,157$5.548.31-52.35Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-07Sell27,2436,071,447$5.35145.75-50.65Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-02Sell22,7576,098,690$5.42123.34-51.29Link
SCHOENHARD GRANTChief Scientific Officer2010-06-16Sell1,50048,187$5.458.18-51.56Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-06-03Sell50,0006,121,447$5.53276.5-52.26Link
SCHOENHARD GRANTChief Scientific Officer2010-05-27Sell10,97948,187$5.7463.02-54.01Link
SCHOENHARD GRANTChief Scientific Officer2010-05-19Sell2,48648,187$5.7714.34-54.25Link
SCHOENHARD GRANTChief Scientific Officer2010-05-18Sell13,03548,187$5.7775.21-54.25Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-06Sell6,5766,171,447$5.6136.89-52.94Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-05Sell43,4246,178,023$5.91256.64-55.33Link
FRIEDMANN NADAVCOO2010-05-04Sell15,000275,951$5.9589.25-55.63Link
SCHOENHARD GRANTChief Scientific Officer2010-04-16Sell26,50048,187$6.29166.69-58.03Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-04-07Sell5,8006,221,447$6.2336.13-57.62Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-04-06Sell32,2006,227,247$6.25201.25-57.76Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-04-01Sell12,0006,259,447$6.1673.92-57.14Link
FRIEDMANN NADAVCOO2010-04-01Sell15,000287,195$6.1792.55-57.21Link
SCHOENHARD GRANTChief Scientific Officer2010-03-16Sell35,00048,187$6.13214.55-56.93Link
O DONNELL MICHAEL JDirector2010-03-11Sell25,0005,775$6.14153.5-57Link
BARBIER REMICEO and Chair of Board, 10% Owner2010-03-03Sell5,4436,271,447$6.1333.37-56.93Link
BARBIER REMICEO and Chair of the Board, 10% Owner2010-03-02Sell44,5576,276,890$6.07270.46-56.51Link
BARBIER REMICEO, President, Chairman of Bd, 10% Owner2010-02-02Sell50,0006,350,247$5.32266-50.38Link
BARBIER REMICEO, Chairman of Board, 10% Owner2010-01-06Sell50,0006,372,475$5.39269.5-51.02Link
FRIEDMANN NADAVCOO2009-11-16Sell15,000302,258$575-47.2Link
BARBIER REMICEO,, 10% Owner2009-11-05Sell50,0006,472,475$4.83241.5-45.34Link
BARBIER REMICEO, 10% Owner2009-10-02Sell20,0006,552,475$5.1102-48.24Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-09-29Sell3,076,9153,230,204$4.9815323.04-46.99Link
BARBIER REMICEO, 10% Owner2009-09-11Sell23,2006,599,275$5.23121.34-49.52Link
RODDY PETER SCFO2009-08-31Sell40,00054,783$5.08203.2-48.03Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-08-07Sell1,663,0006,307,119$3.966585.48-33.33Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-14Sell90,7787,970,119$4.23383.99-37.59
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.44-42.36
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.44-42.36
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-15Sell195,9215,810,453$5.07993.32-47.93
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-15Sell285,7038,428,897$5.071448.51-47.93
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-10Sell310,5216,006,374$5.271636.45-49.91
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-10Sell461,2748,714,600$5.272430.91-49.91
BARBIER REMIPresident and CEO, 10% Owner2009-06-05Sell50,0006,644,075$5.26263-49.81
BARBIER REMICEO and Chairman of the Board, 10% Owner2009-05-16Sell26,8006,572,475$5.23140.16-49.52Link
RODDY PETER SVice President & CFO2009-05-01Buy3,37454,783$3.7712.72-29.97
FRIEDMANN NADAVCOO2009-05-01Buy3,374317,258$3.7712.72-29.97
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-04-06Sell900,0009,175,874$4.153735-36.39
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-04-06Sell621,8606,316,895$4.152580.72-36.39
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-03-02Sell1,000,00010,075,874$3.583580-26.26
BARBIER REMIPresident and CEO, Director, 10% Owner2009-02-03Sell50,0006,694,075$6.46323-59.13
BARBIER REMIPresident and CEO, Director, 10% Owner2009-01-05Sell50,0006,744,075$6.13306.5-56.93
BARBIER REMIPresident and CEO, Director, 10% Owner2008-12-02Sell50,0006,794,075$8.58429-69.23
BARBIER REMIPresident and CEO, Director, 10% Owner2008-11-04Sell50,0006,844,075$8.81440.5-70.03
BARBIER REMIPresident and CEO, Director, 10% Owner2008-10-02Sell50,0006,896,575$9.76488-72.95
BARBIER REMIPresident and CEO, Director, 10% Owner2008-09-03Sell50,0006,850,200$9.41470.5-71.94
BARBIER REMIPresident and CEO, Director, 10% Owner2008-08-04Sell50,0006,775,200$8.34417-68.35
BARBIER REMIPresident and CEO, Director, 10% Owner2008-07-02Sell50,0006,825,200$7.71385.5-65.76
BARBIER REMIPresident and CEO, Director, 10% Owner2008-06-03Sell50,0006,875,200$8.04402-67.16
BARBIER REMIPresident and CEO, Director, 10% Owner2008-05-02Sell50,0006,925,200$7.38369-64.23
RODDY PETER SVice President and CFO2008-05-01Buy3,26825,709$6.320.59-58.1
FRIEDMANN NADAVChief Operating & Med. Officer, Director2008-05-01Buy3,267208,572$6.320.58-58.1
BARBIER REMIPresident and CEO, Director, 10% Owner2008-04-02Sell50,0006,975,200$8.59429.5-69.27
BARBIER REMIPresident and CEO, Director, 10% Owner2008-03-04Sell50,0007,041,200$8.16408-67.65
EASTBOURNE CAPITAL MANAGEMENT10% Owner2008-02-29Buy174,70011,075,874$9.111591.52-71.02
BARBIER REMIPresident and CEO, Director, 10% Owner2008-02-04Sell50,0007,091,200$8.88444-70.27
BARBIER REMIPresident and CEO, Director, 10% Owner2008-01-03Sell50,0007,141,200$10.19509.5-74.09
BARBIER REMIPresident and CEO, Director, 10% Owner2007-12-04Sell50,0007,191,200$10.26513-74.27
BARBIER REMIPresident and CEO, Director, 10% Owner2007-11-02Sell50,0007,241,200$10.91545.5-75.8
BARBIER REMIPresident and CEO2007-10-02Sell50,0007,291,200$9.7485-72.78
BARBIER REMIPresident and CEO2007-09-05Sell50,0007,341,200$9.53476.5-72.3
BARBIER REMIPresident and CEO2007-08-02Sell50,0007,391,200$8.45422.5-68.76
BARBIER REMIPresident and CEO2007-07-03Sell50,0001,441,200$8.91445.5-70.37
BARBIER REMIPresident and CEO2007-07-03Sell50,0007,441,200$8.91445.5-70.37
RODDY PETER SVice President and CFO2007-06-11Sell10,00021,415$8.1781.7-67.69
BARBIER REMIPresident and CEO2007-06-04Sell50,0007,491,200$8.39419.5-68.53
BARBIER REMIPresident and CEO2007-05-02Sell50,0007,541,200$8.2410-67.8
RODDY PETER SCFO2007-04-10Sell10,00016,757$7.9779.7-66.88
BARBIER REMIPresident and CEO2007-04-03Sell50,0007,591,200$7.89394.5-66.54
RODDY PETER SChief Financial Officer2007-03-12Sell10,00016,757$7.3973.9-64.28
BARBIER REMIPresident and CEO2007-03-02Sell50,0007,641,200$7.67383.5-65.58
FRIEDMANN NADAVChief Operating & Med. Officer2007-02-28Sell4,000150,596$7.8531.4-66.37
BARBIER REMIPresident and CEO2007-02-16Sell50,0007,705,200$8.41420.5-68.61
RODDY PETER SChief Financial Officer2007-02-12Sell10,00016,757$8.5485.4-69.09
FRIEDMANN NADAVChief Operating & Med. Officer2007-01-31Sell4,000154,596$8.935.6-70.34
RODDY PETER SChief Financial Officer2007-01-10Sell10,00016,757$8.686-69.3
FRIEDMANN NADAVChief Operating & Med. Officer2006-12-29Sell4,000158,596$9.1336.52-71.08
RODDY PETER SChief Financial Officer2006-12-11Sell10,00016,757$8.5585.5-69.12
BARBIER REMIPresident and CEO2006-12-04Sell35,0007,755,200$8.55299.25-69.12
FRIEDMANN NADAVChief Operating & Med. Officer2006-11-30Sell4,000162,596$8.5934.36-69.27
RODDY PETER SChief Financial Officer2006-11-10Sell10,00020,757$8.0180.1-67.04
BARBIER REMIPresident and CEO2006-11-06Sell35,0007,790,200$8.28289.8-68.12
FRIEDMANN NADAVOperating & Med. Officer2006-10-31Sell4,000165,275$8.3233.28-68.27
RODDY PETER SChief Financial Officer2006-10-10Sell10,00016,155$8.4184.1-68.61
BARBIER REMIPresident and CEO2006-10-09Sell35,0007,825,200$8.56299.6-69.16
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-19Buy2,9005,666,732$7.8822.85-66.5Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-14Buy7005,663,832$7.885.52-66.5Link
RODDY PETER SCFO2006-09-11Sell10,00016,155$7.8678.6-66.41Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-11Buy4,0645,663,132$7.8832.02-66.5Link
BARBIER REMIPresident and CEO, 10% Owner2006-09-05Sell35,0007,860,200$8.39293.65-68.53Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-08-31Sell4,000173,275$8.3733.48-68.46Link
RODDY PETER SCFO2006-08-10Sell10,00016,155$8.8388.3-70.1Link
BARBIER REMIPresident & CEO, 10% Owner2006-08-07Sell35,0007,895,200$8.56299.6-69.16Link
RODDY PETER SCFO2006-07-10Sell10,00016,155$8.3383.3-68.31Link
BARBIER REMIPresident and CEO, 10% Owner2006-07-03Sell35,0007,930,200$8.38293.3-68.5Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-19Buy81,4005,659,068$7.79634.11-66.11Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-16Buy114,3005,577,668$7.86898.4-66.41Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-14Buy26,3005,463,368$7.93208.56-66.71Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-13Buy72,5175,437,068$8.01580.86-67.04Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-12Buy2,0005,364,551$8.0416.08-67.16Link
RODDY PETER SCFO2006-06-12Sell10,00016,155$8.1381.3-67.53Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-08Buy42,6005,362,551$8.15347.19-67.61Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-06Buy3,8005,319,951$8.1931.12-67.77Link
BARBIER REMIPresident and CEO, 10% Owner2006-06-05Sell35,0007,965,200$8.68303.8-69.59Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-25Buy3,0655,316,151$8.1925.1-67.77Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-24Buy37,4005,313,086$8.19306.31-67.77Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-22Buy21,7005,275,686$8.19177.72-67.77Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-19Buy1,4005,253,986$8.1911.47-67.77Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-18Buy20,9775,252,586$8.19171.8-67.77Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-17Buy83,7005,231,609$8.31695.55-68.23Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-16Buy34,0005,147,909$8.44286.96-68.72Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-12Buy16,6005,113,909$8.44140.1-68.72Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-11Buy54,9005,097,309$8.54468.85-69.09Link
RODDY PETER SCFO2006-05-10Sell10,00016,155$8.585-68.94Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-09Buy94,4005,042,409$8.54806.18-69.09Link
BARBIER REMIPresident and CEO, 10% Owner2006-05-08Sell35,0008,000,200$8.63302.05-69.41Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-05-01Buy4,154177,275$4.4318.4-40.41Link
RODDY PETER SCFO2006-05-01Buy2,18416,155$4.439.68-40.41Link
RODDY PETER SCFO2006-04-10Sell10,00013,971$9.2792.7-71.52Link
BARBIER REMIPresident and CEO, 10% Owner2006-04-03Sell35,0008,035,200$10.61371.35-75.12Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-03-15Sell25,000174,121$10.86271.5-75.69Link
RODDY PETER SCFO2006-03-10Sell10,00013,971$10.74107.4-75.42Link
BARBIER REMIPresident and CEO, 10% Owner2006-03-06Sell35,0008,070,200$10.56369.6-75Link
O DONNELL MICHAEL JDirector2006-02-23Sell19,05439,885$11.22213.79-76.47Link
BARBIER REMICEO, 10% Owner2006-02-07Sell2,0008,116,200$8.7817.56-69.93Link
BARBIER REMICEO, 10% Owner2006-02-07Sell33,0008,118,200$9.09299.97-70.96Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-30Buy32,5524,948,009$6.79221.03-61.12Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-29Buy31,0894,915,457$6.79211.09-61.12Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-20Buy45,8124,884,368$6.79311.06-61.12Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-16Buy4,0004,838,556$6.7827.12-61.06Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-15Buy29,8804,834,556$6.78202.59-61.06Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-09Buy4,4104,804,676$6.1327.03-56.93Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-08Buy12,9004,800,266$6.1379.08-56.93Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-04Buy38,4564,787,366$5.97229.58-55.78Link
RODDY PETER SVice President & CFO2005-11-01Buy1,44416,971$4.436.4-40.41Link
FRIEDMANN NADAVChief Operating & Medical Off.2005-11-01Buy4,121199,121$4.4318.26-40.41Link
FRIEDMANN NADAVCOO2005-10-28Buy25,000195,000$25032Link
FRIEDMANN NADAVCOO2005-10-10Buy15,000170,000$23032Link
FRIEDMANN NADAVCOO2005-10-05Buy10,000155,000$22032Link
RODDY PETER SCFO2004-10-29Buy2,99315,527$2.748.2-3.65Link
RODDY PETER SVice President & CFO2004-04-30Buy12,5340$2.7434.34-3.65Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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