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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Remi BarbierN/A4,369,7319.55%2014-07-14
Sanford R. RobertsonN/A438,3620.96%2014-03-21
Nadav Friedmann,M.D.N/A359,8930.79%2014-11-18
Peter S. RoddyN/A103,0930.23%2014-07-14
Grant L. Schoenhard,PhDN/A78,5510.17%2014-07-11
Michael J. O'Donnell,Esq.N/A32,118less than 0.1%2014-03-21
Robert Z. Gussin,PhDN/A27,360less than 0.1%2014-05-27

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
ROBERTSON SANFORDDirector2013-11-06Buy50,000369,727$3.73186.5-35.12369,727 (Direct)
FRIEDMANN NADAVCOO2011-10-18Sell25,000259,255$4.44111-45.5259,255 (Direct)
FRIEDMANN NADAVCOO2011-10-04Sell25,000284,255$4.81120.3-49.69284,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-10-04Sell382,0004,263,076$4.591753.4-47.284,263,076 (Direct)
FRIEDMANN NADAVCOO2011-09-15Sell25,000309,255$4.89122.3-50.51309,255 (Direct)
Sabretooth Master Fund, L.P.10% Owner2011-08-08Sell44,4174,645,076$4.2186.6-42.384,645,076 (Direct)
BARBIER REMICEO, Chairman of the Board, 10% Owner
(Click for the stocks that their CEOs have bought)
2011-08-08Buy5,0005,948,053$4.2221.1-42.655,948,053 (Direct)
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-10-04Sell50,0005,929,587$6.2310-60.97Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-07Sell28,5975,979,587$5.69162.7-57.47Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-09-02Sell21,4036,008,184$5.81124.4-58.35Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-09Sell19,4696,029,587$5.64109.8-57.09Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-08-04Sell22,3916,049,056$5.71127.9-57.62Link
SCHOENHARD GRANTChief Scientific Officer2010-07-16Sell1,50048,157$5.548.3-56.32Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-07Sell27,2436,071,447$5.35145.8-54.77Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-07-02Sell22,7576,098,690$5.42123.3-55.35Link
SCHOENHARD GRANTChief Scientific Officer2010-06-16Sell1,50048,187$5.458.2-55.6Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-06-03Sell50,0006,121,447$5.53276.5-56.24Link
SCHOENHARD GRANTChief Scientific Officer2010-05-27Sell10,97948,187$5.7463-57.84Link
SCHOENHARD GRANTChief Scientific Officer2010-05-19Sell2,48648,187$5.7714.3-58.06Link
SCHOENHARD GRANTChief Scientific Officer2010-05-18Sell13,03548,187$5.7775.2-58.06Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-06Sell6,5766,171,447$5.6136.9-56.86Link
BARBIER REMICEO and Chairman of BOD, 10% Owner2010-05-05Sell43,4246,178,023$5.91256.6-59.05Link
FRIEDMANN NADAVCOO2010-05-04Sell15,000275,951$5.9589.3-59.33Link
SCHOENHARD GRANTChief Scientific Officer2010-04-16Sell26,50048,187$6.29166.7-61.53Link
BARBIER REMICEO and Chairman of Board, 10% Owner2010-04-07Sell5,8006,221,447$6.2336.1-61.16Link
BARBIER REMICEO & Chairman of the Board, 10% Owner2010-04-06Sell32,2006,227,247$6.25201.3-61.28Link
BARBIER REMICEO and Chairman of the Board, 10% Owner2010-04-01Sell12,0006,259,447$6.1673.9-60.71Link
FRIEDMANN NADAVCOO2010-04-01Sell15,000287,195$6.1792.6-60.78Link
SCHOENHARD GRANTChief Scientific Officer2010-03-16Sell35,00048,187$6.13214.6-60.52Link
O DONNELL MICHAEL JDirector2010-03-11Sell25,0005,775$6.14153.5-60.59Link
BARBIER REMICEO and Chair of Board, 10% Owner2010-03-03Sell5,4436,271,447$6.1333.4-60.52Link
BARBIER REMICEO and Chair of the Board, 10% Owner2010-03-02Sell44,5576,276,890$6.07270.5-60.13Link
BARBIER REMICEO, President, Chairman of Bd, 10% Owner2010-02-02Sell50,0006,350,247$5.32266-54.51Link
BARBIER REMICEO, Chairman of Board, 10% Owner2010-01-06Sell50,0006,372,475$5.39269.5-55.1Link
FRIEDMANN NADAVCOO2009-11-16Sell15,000302,258$575-51.6Link
BARBIER REMICEO,, 10% Owner2009-11-05Sell50,0006,472,475$4.83241.5-49.9Link
BARBIER REMICEO, 10% Owner2009-10-02Sell20,0006,552,475$5.1102-52.55Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-09-29Sell3,076,9153,230,204$4.9815323-51.41Link
BARBIER REMICEO, 10% Owner2009-09-11Sell23,2006,599,275$5.23121.3-53.73Link
RODDY PETER SCFO2009-08-31Sell40,00054,783$5.08203.2-52.36Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-08-07Sell1,663,0006,307,119$3.966585.5-38.89Link
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-14Sell90,7787,970,119$4.23384-42.79
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.4-47.16
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-07-07Sell368,0008,060,897$4.581685.4-47.16
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-15Sell195,9215,810,453$5.07993.3-52.27
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-15Sell285,7038,428,897$5.071448.5-52.27
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-06-10Sell310,5216,006,374$5.271636.4-54.08
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-06-10Sell461,2748,714,600$5.272430.9-54.08
BARBIER REMIPresident and CEO, 10% Owner2009-06-05Sell50,0006,644,075$5.26263-53.99
BARBIER REMICEO and Chairman of the Board, 10% Owner2009-05-16Sell26,8006,572,475$5.23140.2-53.73Link
RODDY PETER SVice President & CFO2009-05-01Buy3,37454,783$3.7712.7-35.81
FRIEDMANN NADAVCOO2009-05-01Buy3,374317,258$3.7712.7-35.81
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-04-06Sell900,0009,175,874$4.153735-41.69
BLACK BEAR OFFSHORE MASTER FUN10% Owner2009-04-06Sell621,8606,316,895$4.152580.7-41.69
EASTBOURNE CAPITAL MANAGEMENT10% Owner2009-03-02Sell1,000,00010,075,874$3.583580-32.4
BARBIER REMIPresident and CEO, Director, 10% Owner2009-02-03Sell50,0006,694,075$6.46323-62.54
BARBIER REMIPresident and CEO, Director, 10% Owner2009-01-05Sell50,0006,744,075$6.13306.5-60.52
BARBIER REMIPresident and CEO, Director, 10% Owner2008-12-02Sell50,0006,794,075$8.58429-71.79
BARBIER REMIPresident and CEO, Director, 10% Owner2008-11-04Sell50,0006,844,075$8.81440.5-72.53
BARBIER REMIPresident and CEO, Director, 10% Owner2008-10-02Sell50,0006,896,575$9.76488-75.2
BARBIER REMIPresident and CEO, Director, 10% Owner2008-09-03Sell50,0006,850,200$9.41470.5-74.28
BARBIER REMIPresident and CEO, Director, 10% Owner2008-08-04Sell50,0006,775,200$8.34417-70.98
BARBIER REMIPresident and CEO, Director, 10% Owner2008-07-02Sell50,0006,825,200$7.71385.5-68.61
BARBIER REMIPresident and CEO, Director, 10% Owner2008-06-03Sell50,0006,875,200$8.04402-69.9
BARBIER REMIPresident and CEO, Director, 10% Owner2008-05-02Sell50,0006,925,200$7.38369-67.21
RODDY PETER SVice President and CFO2008-05-01Buy3,26825,709$6.320.6-61.59
FRIEDMANN NADAVChief Operating & Med. Officer, Director2008-05-01Buy3,267208,572$6.320.6-61.59
BARBIER REMIPresident and CEO, Director, 10% Owner2008-04-02Sell50,0006,975,200$8.59429.5-71.83
BARBIER REMIPresident and CEO, Director, 10% Owner2008-03-04Sell50,0007,041,200$8.16408-70.34
EASTBOURNE CAPITAL MANAGEMENT10% Owner2008-02-29Buy174,70011,075,874$9.111591.5-73.44
BARBIER REMIPresident and CEO, Director, 10% Owner2008-02-04Sell50,0007,091,200$8.88444-72.75
BARBIER REMIPresident and CEO, Director, 10% Owner2008-01-03Sell50,0007,141,200$10.19509.5-76.25
BARBIER REMIPresident and CEO, Director, 10% Owner2007-12-04Sell50,0007,191,200$10.26513-76.41
BARBIER REMIPresident and CEO, Director, 10% Owner2007-11-02Sell50,0007,241,200$10.91545.5-77.82
BARBIER REMIPresident and CEO2007-10-02Sell50,0007,291,200$9.7485-75.05
BARBIER REMIPresident and CEO2007-09-05Sell50,0007,341,200$9.53476.5-74.61
BARBIER REMIPresident and CEO2007-08-02Sell50,0007,391,200$8.45422.5-71.36
BARBIER REMIPresident and CEO2007-07-03Sell50,0001,441,200$8.91445.5-72.84
BARBIER REMIPresident and CEO2007-07-03Sell50,0007,441,200$8.91445.5-72.84
RODDY PETER SVice President and CFO2007-06-11Sell10,00021,415$8.1781.7-70.38
BARBIER REMIPresident and CEO2007-06-04Sell50,0007,491,200$8.39419.5-71.16
BARBIER REMIPresident and CEO2007-05-02Sell50,0007,541,200$8.2410-70.49
RODDY PETER SCFO2007-04-10Sell10,00016,757$7.9779.7-69.64
BARBIER REMIPresident and CEO2007-04-03Sell50,0007,591,200$7.89394.5-69.33
RODDY PETER SChief Financial Officer2007-03-12Sell10,00016,757$7.3973.9-67.25
BARBIER REMIPresident and CEO2007-03-02Sell50,0007,641,200$7.67383.5-68.45
FRIEDMANN NADAVChief Operating & Med. Officer2007-02-28Sell4,000150,596$7.8531.4-69.17
BARBIER REMIPresident and CEO2007-02-16Sell50,0007,705,200$8.41420.5-71.22
RODDY PETER SChief Financial Officer2007-02-12Sell10,00016,757$8.5485.4-71.66
FRIEDMANN NADAVChief Operating & Med. Officer2007-01-31Sell4,000154,596$8.935.6-72.81
RODDY PETER SChief Financial Officer2007-01-10Sell10,00016,757$8.686-71.86
FRIEDMANN NADAVChief Operating & Med. Officer2006-12-29Sell4,000158,596$9.1336.5-73.49
RODDY PETER SChief Financial Officer2006-12-11Sell10,00016,757$8.5585.5-71.7
BARBIER REMIPresident and CEO2006-12-04Sell35,0007,755,200$8.55299.3-71.7
FRIEDMANN NADAVChief Operating & Med. Officer2006-11-30Sell4,000162,596$8.5934.4-71.83
RODDY PETER SChief Financial Officer2006-11-10Sell10,00020,757$8.0180.1-69.79
BARBIER REMIPresident and CEO2006-11-06Sell35,0007,790,200$8.28289.8-70.77
FRIEDMANN NADAVOperating & Med. Officer2006-10-31Sell4,000165,275$8.3233.3-70.91
RODDY PETER SChief Financial Officer2006-10-10Sell10,00016,155$8.4184.1-71.22
BARBIER REMIPresident and CEO2006-10-09Sell35,0007,825,200$8.56299.6-71.73
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-19Buy2,9005,666,732$7.8822.9-69.29Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-14Buy7005,663,832$7.885.5-69.29Link
RODDY PETER SCFO2006-09-11Sell10,00016,155$7.8678.6-69.21Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-09-11Buy4,0645,663,132$7.8832-69.29Link
BARBIER REMIPresident and CEO, 10% Owner2006-09-05Sell35,0007,860,200$8.39293.7-71.16Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-08-31Sell4,000173,275$8.3733.5-71.09Link
RODDY PETER SCFO2006-08-10Sell10,00016,155$8.8388.3-72.59Link
BARBIER REMIPresident & CEO, 10% Owner2006-08-07Sell35,0007,895,200$8.56299.6-71.73Link
RODDY PETER SCFO2006-07-10Sell10,00016,155$8.3383.3-70.95Link
BARBIER REMIPresident and CEO, 10% Owner2006-07-03Sell35,0007,930,200$8.38293.3-71.12Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-19Buy81,4005,659,068$7.79634.1-68.93Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-16Buy114,3005,577,668$7.86898.4-69.21Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-14Buy26,3005,463,368$7.93208.6-69.48Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-13Buy72,5175,437,068$8.01580.9-69.79Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-12Buy2,0005,364,551$8.0416.1-69.9Link
RODDY PETER SCFO2006-06-12Sell10,00016,155$8.1381.3-70.23Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-08Buy42,6005,362,551$8.15347.2-70.31Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-06-06Buy3,8005,319,951$8.1931.1-70.45Link
BARBIER REMIPresident and CEO, 10% Owner2006-06-05Sell35,0007,965,200$8.68303.8-72.12Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-25Buy3,0655,316,151$8.1925.1-70.45Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-24Buy37,4005,313,086$8.19306.3-70.45Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-22Buy21,7005,275,686$8.19177.7-70.45Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-19Buy1,4005,253,986$8.1911.5-70.45Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-18Buy20,9775,252,586$8.19171.8-70.45Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-17Buy83,7005,231,609$8.31695.5-70.88Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-16Buy34,0005,147,909$8.44287-71.33Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-12Buy16,6005,113,909$8.44140.1-71.33Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-11Buy54,9005,097,309$8.54468.8-71.66Link
RODDY PETER SCFO2006-05-10Sell10,00016,155$8.585-71.53Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2006-05-09Buy94,4005,042,409$8.54806.2-71.66Link
BARBIER REMIPresident and CEO, 10% Owner2006-05-08Sell35,0008,000,200$8.63302.1-71.96Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-05-01Buy4,154177,275$4.4318.4-45.37Link
RODDY PETER SCFO2006-05-01Buy2,18416,155$4.439.7-45.37Link
RODDY PETER SCFO2006-04-10Sell10,00013,971$9.2792.7-73.89Link
BARBIER REMIPresident and CEO, 10% Owner2006-04-03Sell35,0008,035,200$10.61371.4-77.19Link
FRIEDMANN NADAVChief Operating & Med. Officer2006-03-15Sell25,000174,121$10.86271.5-77.72Link
RODDY PETER SCFO2006-03-10Sell10,00013,971$10.74107.4-77.47Link
BARBIER REMIPresident and CEO, 10% Owner2006-03-06Sell35,0008,070,200$10.56369.6-77.08Link
O DONNELL MICHAEL JDirector2006-02-23Sell19,05439,885$11.22213.8-78.43Link
BARBIER REMICEO, 10% Owner2006-02-07Sell2,0008,116,200$8.7817.6-72.44Link
BARBIER REMICEO, 10% Owner2006-02-07Sell33,0008,118,200$9.09300-73.38Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-30Buy32,5524,948,009$6.79221-64.36Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-29Buy31,0894,915,457$6.79211.1-64.36Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-20Buy45,8124,884,368$6.79311.1-64.36Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-16Buy4,0004,838,556$6.7827.1-64.31Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-12-15Buy29,8804,834,556$6.78202.6-64.31Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-09Buy4,4104,804,676$6.1327-60.52Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-08Buy12,9004,800,266$6.1379.1-60.52Link
BLACK BEAR OFFSHORE MASTER FUN10% Owner2005-11-04Buy38,4564,787,366$5.97229.6-59.46Link
RODDY PETER SVice President & CFO2005-11-01Buy1,44416,971$4.436.4-45.37Link
FRIEDMANN NADAVChief Operating & Medical Off.2005-11-01Buy4,121199,121$4.4318.3-45.37Link
FRIEDMANN NADAVCOO2005-10-28Buy25,000195,000$25021Link
FRIEDMANN NADAVCOO2005-10-10Buy15,000170,000$23021Link
FRIEDMANN NADAVCOO2005-10-05Buy10,000155,000$22021Link
RODDY PETER SCFO2004-10-29Buy2,99315,527$2.748.2-11.68Link
RODDY PETER SVice President & CFO2004-04-30Buy12,5340$2.7434.3-11.68Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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