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Top Direct Holders

HolderPositionShares% of Shares
Report Date
Dr. Carl Spana,PhDN/A2,011,0791.86%2016-09-07
Stephen T. WillsN/A1,842,0411.7%2016-09-07
Dr. John K.A. Prendergast,PhDN/A466,7670.43%2016-06-09
Trevor Hallam,PhDN/A384,0000.36%2010-03-26
Robert K. Deveer,JrN/A294,6850.27%2016-06-09
J. Stanley HullN/A265,6250.25%2016-06-09
Dr. Zola P. Horovitz,PhDN/A250,6660.23%2015-12-08
Dr. Alan W. Dunton,M.D.N/A195,6450.18%2016-06-09
Ms. Angela RossettiN/A140,6250.13%2016-06-09
Ms. Arlene M. MorrisN/A80,625less than 0.1%2016-06-09

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Hull Joseph StanleyDirector2015-12-04Buy2,50021,500$0.661.65-13.6421,500 (Direct)
Hull Joseph StanleyDirector2015-11-19Buy2,00019,000$0.651.3-12.3119,000 (Direct)
DEVEER ROBERT K JRDirector2015-10-02Buy10,000222,393$0.828.2-30.49222,393 (Direct)
BVF PARTNERS L P/IL10% Owner2014-02-27Sell293,8253,705,128$1.09320.27-47.71
772,480 (By Biotechnology Value Fund, L.P.)
438,127 (By Biotechnology Value Fund II, L.P.)
2,494,521 (By BVF Investments, L.L.C.)
BVF PARTNERS L P/IL10% Owner2014-02-26Sell540,1813,998,953$1.14615.81-50
831,868 (By Biotechnology Value Fund, L.P.)
471,737 (By Biotechnology Value Fund II, L.P.)
2,695,348 (By BVF Investments, L.L.C.)
BVF PARTNERS L P/IL10% Owner2014-02-19Sell305,9664,539,134$1.17357.98-51.28
936,288 (By Biotechnology Value Fund, L.P.)
530,923 (By Biotechnology Value Fund II, L.P.)
3,071,923 (By BVF Investments, L.L.C.)
DUNTON ALAN WDirector2013-03-19Buy1,0007,520$0.580.58-1.72
7,520 (By SEP IRA and Danerius LLC)
DUNTON ALAN WDirector2013-02-01Buy2,0006,520$0.591.18-3.39
6,520 (By SEP IRA and Danerius LLC)
TABER ROBERT IDirector2013-01-28Buy5,0005,500$0.592.95-3.39
5,500 (By SEP IRA)
(Click for the stocks that their CEOs have bought)
2012-12-31Buy10,000207,341$0.575.70207,341 (Direct)
WILLS STEPHEN TExecutive VP and CFO/COO2012-12-28Buy10,000193,942$0.565.61.79193,942 (Direct)
Hull Joseph StanleyDirector2012-12-24Buy2,0002,000$0.651.3-12.312,000 (Direct)
HOROVITZ ZOLA PDirector2012-12-24Buy10,00010,500$0.66-510,500 (Direct)
MOLINOFF PERRY BDirector2012-12-24Buy10,00011,000$0.616.1-6.5611,000 (Direct)
DEVEER ROBERT K JRDirector2012-12-14Buy21,96037,160$0.715.37-18.5715,100 (Direct)
22,060 (By spouse)
DUNTON ALAN WDirector2012-11-16Sell1,0004,520$0.680.68-16.18
4,520 (By Danerius LLC)
DUNTON ALAN WDirector2012-09-04Buy1,0005,520$0.580.58-1.72
5,520 (By Danerius LLC)
DUNTON ALAN WDirector2012-08-28Buy5204,520$0.560.291.79
4,520 (By Danerius LLC)
DUNTON ALAN WDirector2012-01-11Buy1,0004,000$0.430.4332.564,000 (Direct)
DUNTON ALAN WDirector2011-11-16Buy1,0003,000$0.50.5143,000 (Direct)
PROQUEST INVESTMENTS LP10% Owner2005-11-29Sell35,800580,397$39.21403.36-98.55Link
Hallam TrevorExec. VP - R&D2005-11-10Buy250250$20.25.05-97.18Link
WILLS STEPHEN TExec. VP & CFO2005-11-10Buy4002,850$20.18.04-97.16Link
SPANA CARLPresident & CEO2005-11-10Buy5004,267$20.310.15-97.19Link
PRENDERGAST JOHN K ADirector2005-05-25Buy4001,767$20.88.32-97.26Link
WILLS STEPHEN TExec. VP and CFO2005-05-25Buy4002,450$19.87.92-97.12Link
SPANA CARLPresident and CEO2005-05-25Buy5003,767$20.710.35-97.25Link
SPANA CARLPresident and CEO2004-11-11Buy6003,267$2615.6-97.81Link
WILLS STEPHEN TExec. Vice President and CFO2004-11-11Buy5002,050$25.812.9-97.79Link
SPANA CARLPresident and CEO2003-11-18Buy1,0002,667$27.527.5-97.93Link
WILLS STEPHEN TExecutive VP and CFO2003-11-18Buy7501,550$27.420.55-97.92Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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