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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Julia G. Levy, PhDN/A445,4800.84%2004-11-19
Mr. Robert L ButchofskyN/A168,8470.32%2012-03-20
Mr. Jeffrey A. MecklerN/A107,0000.2%2015-06-29
Dr. Geoffrey F. Cox,PhDN/A78,5000.15%2015-06-29
Mr. Jason M. AryehDirector74,0000.14%2015-12-29
Dr. John W. Kozarich,PhDN/A57,0000.11%2015-06-29
Dr. Stephen L. Sabba,M.D.N/A37,000less than 0.1%2015-06-29
Mr. John C. Thomas,JrN/A37,000less than 0.1%2015-06-29
Cameron NelsonN/A35,000less than 0.1%2009-11-06
Dr. George J. VuturoN/A26,813less than 0.1%2004-11-19

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
STONEPINE CAPITAL, L.P.10% Owner2016-09-15Buy133,4965,778,496$1.55206.9221.295,778,496 (Direct)
Aryeh JasonDirector2015-12-29Buy18,400535,478$2.546-24.874,000 (Direct)
461,478 (By JALAA Equities, LP)
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2015-06-16Sell8,865,0360$3.4730761.67-45.82
0 (See Footnote)
Axial Capital Master, L.P.10% Owner2015-06-16Sell7,563,0530$3.4726243.79-45.82Link
Aryeh JasonDirector2015-06-16Buy288,000467,078$3.47999.36-45.82179,078 (Direct)
288,000 (By JALAA Equities, LP)
KOZARICH JOHN WDirector2014-12-22Buy10,00022,000$3.5935.9-47.6322,000 (Direct)
Meckler Jeffrey ADirector2014-12-18Buy20,00072,000$3.672-47.7872,000 (Direct)
NB Public Equity K/S10% Owner2014-07-11Sell1,000,0006,447,626$5.85800-67.596,447,626 (Direct)
Axial Capital Master, L.P.10% Owner2013-07-01Sell288,8907,563,053$4.391268.23-57.187,563,053 (Direct)
Meckler Jeffrey ADirector2013-06-28Buy30,00050,000$4.36130.8-56.8850,000 (Direct)
Jagpal SukhiCFO
(Click for the stocks that their CFOs have bought)
2013-05-14Sell10,0001,200$7.9579.5-76.351,200 (Direct)
Jagpal, SukhiSenior Officer2013-05-14Sell9,9000$8.0779.89-76.7
Jagpal, SukhiSenior Officer2013-05-14Sell1000$8.080.81-76.73
KOZARICH JOHN WDirector2013-05-13Buy10,00010,000$7.9779.7-76.4110,000 (Direct)
Kozarich, John W.Director2013-05-13Buy3,8190$7.9630.4-76.38
Kozarich, John W.Director2013-05-13Buy2000$7.971.59-76.41
Kozarich, John W.Director2013-05-13Buy2,0000$7.9615.92-76.38
Kozarich, John W.Director2013-05-13Buy3,9810$7.9831.77-76.44
Meckler Jeffrey ADirector2013-05-03Buy20,00020,000$7.96159.2-76.3820,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2013-05-03Sell90,00020,000$7.85706.5-76.0520,000 (Direct)
Janes, Lana ElizabethSenior Officer2013-05-03Sell5500$8.014.41-76.53
Janes, Lana ElizabethSenior Officer2013-05-03Sell34,4500$000
Janes, Lana ElizabethSenior Officer2013-05-03Sell40,0000$000
Lussow, AlexanderSenior Officer2013-05-03Sell20,0000$7.53150.6-75.03
Lussow, AlexanderSenior Officer2013-05-03Sell5,4100$7.942.74-76.2
Lussow, AlexanderSenior Officer2013-05-03Sell4,0900$7.9132.35-76.23
Lussow, AlexanderSenior Officer2013-05-03Sell3000$7.922.38-76.26
Lussow, AlexanderSenior Officer2013-05-03Sell54,0000$7.95429.3-76.35
Lussow, AlexanderSenior Officer2013-05-03Sell7000$7.955.57-76.35
Lussow, AlexanderSenior Officer2013-05-03Sell3000$7.952.39-76.35
Lussow, AlexanderSenior Officer2013-05-03Sell2000$7.961.59-76.38
Lussow, AlexanderSenior Officer2013-05-03Sell5,0000$7.9839.9-76.44
Meckler, JeffreyDirector2013-05-03Buy1,3570$7.9910.84-76.47
Meckler, JeffreyDirector2013-05-03Buy2000$7.991.6-76.47
Meckler, JeffreyDirector2013-05-03Buy2000$7.981.6-76.44
Meckler, JeffreyDirector2013-05-03Buy3000$7.972.39-76.41
Meckler, JeffreyDirector2013-05-03Buy3,6000$7.9728.69-76.41
Meckler, JeffreyDirector2013-05-03Buy5,1430$7.9640.94-76.38
Meckler, JeffreyDirector2013-05-03Buy9,0000$7.9571.55-76.35
Meckler, JeffreyDirector2013-05-03Buy1000$7.940.79-76.32
Meckler, JeffreyDirector2013-05-03Buy1000$7.950.79-76.34
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-12-28Sell230,00020,000$7.521729.6-7520,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-12-12Sell5,00020,000$8.0240.1-76.5620,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-11-28Sell5,00020,000$7.8839.4-76.1420,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-11-20Sell5,00020,000$7.8139.05-75.9320,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-11-01Sell5,00020,000$7.5237.6-7520,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-10-22Sell5,00020,000$7.7238.6-75.6520,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-10-05Sell5,00020,000$7.7238.6-75.6520,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-09-18Sell5,00020,000$7.5737.85-75.1720,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-09-05Sell5,00020,000$7.5537.75-75.120,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-08-20Sell5,00020,000$7.6738.35-75.4920,000 (Direct)
LUPINI LINDASenior VP, HR & Org. Dev.2012-08-13Sell77,00715,000$7.58583.71-75.215,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-08-08Sell5,00020,000$7.9239.6-76.2620,000 (Direct)
LUPINI LINDASenior VP, HR & Org. Dev.2012-08-08Sell22,99315,000$7.85180.5-76.0515,000 (Direct)
Jagpal SukhiInterim CFO
(Click for the stocks that their CFOs have bought)
2012-08-03Sell67,0001,200$8.19548.73-77.051,200 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-07-24Sell5,00020,000$8.2841.4-77.2920,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-07-09Sell5,00020,000$7.5337.65-75.0320,000 (Direct)
CLARKE C BOYDFormer Director2012-07-09Sell75,4500$7.62574.93-75.33
0 (See Footnote)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-06-21Sell5,00020,000$7.6538.25-75.4220,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2012-06-15Sell5,00020,000$7.4737.35-74.8320,000 (Direct)
NB Public Equity K/S10% Owner2012-05-16Buy50,0007,447,626$6.67333.5-71.817,447,626 (Direct)
CLARKE C BOYDDirector2012-05-15Buy2,45075,450$6.5616.07-71.3475,450 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2011-11-29Sell30,00020,000$6.8204-72.3520,000 (Direct)
Lussow Alexander RSr. VP, Bus. Dev. & Comm. Op.2011-11-23Buy10,00020,000$6.8468.4-72.5120,000 (Direct)
LUPINI LINDASenior VP, HR & Org. Dev.2011-11-21Buy5,00015,000$7.0635.3-73.3715,000 (Direct)
NB Public Equity K/S10% Owner2011-08-31Sell129,9877,397,626$7.26943.71-74.17,397,626 (Direct)
Axial Capital Master, L.P.10% Owner2011-08-30Buy2,489,6127,851,943$6.9517302.8-72.957,851,943 (Direct)
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2011-08-30Buy2,000,0008,865,036$7.2514500-74.07
8,865,036 (See Footnote)
NB Public Equity K/S10% Owner2011-08-29Sell200,0007,527,613$7.081416-73.457,527,613 (Direct)
CLARKE C BOYDDirector2011-06-17Buy4,00073,000$6.7527-72.1573,000 (Direct)
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-11-11Buy72,1006,865,036$5.72412.41-67.13Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-11-08Buy4,3006,792,936$5.624.08-66.43Link
BUTCHOFSKY ROBERTPresident and CEO
(Click for the stocks that their CEOs have bought)
2010-11-05Buy3,000169,897$5.6216.86-66.55Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-11-03Buy2,6006,788,636$5.614.56-66.43Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-11-02Buy171,0006,786,036$5.69972.99-66.96Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-09-01Buy65,8246,615,036$5.75378.49-67.3Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-08-30Buy107,4006,549,212$5.72614.33-67.13Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-08-11Buy100,0006,441,812$5.7570-67.02Link
CLARKE C BOYDDirector2010-08-02Buy3,00069,000$5.7517.25-67.3Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-07-30Buy37,2266,341,812$5.72212.93-67.13Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-07-06Buy109,1576,304,586$5.79632.02-67.53Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-07-02Buy419,2006,195,429$5.742406.21-67.25Link
BUTCHOFSKY ROBERTPresident and CEO2010-06-21Buy5,000166,897$5.7528.75-67.3Link
AXIAL CAPITAL MANAGEMENT, LLC10% Owner2010-06-08Buy300,0005,776,229$6.21860-69.68Link
Panigrahi DipakSVP, R&D and CMO2010-05-07Buy500500$5.712.86-67.08Link
NB Public Equity K/S10% Owner2010-03-16Buy40,8967,727,613$4.99204.07-62.32Link
NB Public Equity K/S10% Owner2010-03-15Buy219,6897,686,717$4.951087.46-62.02Link
NB Public Equity K/S10% Owner2010-03-11Buy130,1787,467,028$4.87633.97-61.4Link
NB Public Equity K/S10% Owner2010-03-10Buy80,2867,336,850$4.82386.98-61Link
Nelson CameronVP, Finance and CFO2009-11-06Buy10,00035,000$3.5835.8-47.49Link
BUTCHOFSKY ROBERTPresident and CEO2009-11-03Buy10,000160,497$3.434-44.71Link
CLARKE C BOYDDirector2009-11-03Buy5,00066,000$3.3916.95-44.54Link
NB Public Equity K/S10% Owner2009-10-21Sell2,000,0007,256,564$3.26400-41.25Link
NB Public Equity K/S10% Owner2009-10-19Sell263,8019,256,564$3.971047.29-52.64Link
Massey Ian JDirector2009-05-14Buy14,49023,440$2.0830.14-9.62
CARTER BRUCE L ADirector2009-05-14Buy20,00020,000$2.0741.4-9.18
CROSSGROVE PETER ADirector2009-05-13Buy10,00042,000$2.1721.7-13.36
CLARKE C BOYDDirector2009-05-12Buy10,00061,000$2.2122.1-14.93
NB Public Equity K/S10% Owner2009-04-09Buy5009,520,365$1.90.95-1.05
NB Public Equity K/S10% Owner2009-04-08Buy336,2939,519,865$1.86625.51.08
NB Public Equity K/S10% Owner2009-04-06Buy312,2059,183,572$1.79558.855.03
NB Public Equity K/S10% Owner2009-04-01Buy239,7618,871,367$1.77424.386.21
NB Public Equity K/S10% Owner2009-03-31Buy419,6288,631,606$1.76738.556.82
NB Public Equity K/S10% Owner2009-03-30Buy433,0188,211,978$1.74753.458.05
NB Public Equity K/S10% Owner2009-03-25Buy320,2547,778,960$1.76563.656.82
NB Public Equity K/S10% Owner2009-03-20Buy11,1937,458,706$1.6918.9211.24
Hao YongVice President, Development2009-03-11Buy6,5916,591$1.419.2933.33
SIMONS JAMES H2009-03-10Sell72,48522,400$1.4910826.17
SIMONS JAMES H2009-03-09Buy31,268377,900$1.4745.9627.89
CLARKE C BOYDDirector2009-03-04Buy10,00051,000$1.6116.116.77
SIMONS JAMES H2009-03-02Sell60,257144,283$1.72103.649.3
SIMONS JAMES H2009-02-27Buy13,500372,600$1.7423.498.05
LUPINI LINDASenior VP, HR & Org. Dev.2009-02-25Buy9,50010,000$1.7616.726.82
CLARKE C BOYDDirector2009-02-23Buy4,00041,000$1.726.889.3
SIMONS JAMES H2009-02-19Sell112,126108,662$1.98222.01-5.05
NB Public Equity K/S10% Owner2009-02-18Buy184,9817,447,513$1.9351.46-1.05
SIMONS JAMES H2009-02-18Buy17,360364,300$2.2138.37-14.93
NB Public Equity K/S10% Owner2009-02-11Sell22,4956,912,505$2.3252.19-18.97
NB Public Equity K/S10% Owner2009-02-11Buy381,7716,917,845$2.3878.07-18.26
NB Public Equity K/S10% Owner2009-02-11Buy27,8356,917,845$2.3264.58-18.97
NB Public Equity K/S10% Owner2009-02-10Buy344,6877,262,532$2.29789.33-17.9
SIMONS JAMES H2009-02-10Sell76,988197,388$2.26173.99-16.81
SIMONS JAMES H2009-02-10Buy31,858205,588$2.3273.91-18.97
CROSSGROVE PETER ADirector2008-11-04Buy10,00032,000$2.5625.6-26.56
CLARKE C BOYDDirector2008-10-30Buy10,00037,000$2.4624.6-23.58
BUTCHOFSKY ROBERTPresident and CEO, Director2008-10-30Buy15,00090,497$2.4236.3-22.31
MENDELSON ALAN CDirector2007-10-30Buy5,00016,000$4.6923.45-59.91
WOOD JACKDirector2007-10-30Buy21,50025,000$4.69100.84-59.91
Nelson CameronVP, Finance & CFO2007-10-26Buy6,00012,000$4.4826.88-58.04
CLARKE C BOYDDirector2007-10-26Buy14,00027,000$4.4962.86-58.13
BUTCHOFSKY ROBERTPresident & CEO, Director2007-10-26Buy39,84774,847$4.57182.1-58.86
HAYES THERESEVP - Invst. Rel. & Corp. Comm2007-10-26Buy5,0005,400$4.4422.2-57.66
VIETOR RICHARD RDirector2007-10-26Buy5,0005,448$4.5322.65-58.5
CROSSGROVE PETER ADirector2007-10-26Buy20,00022,000$4.5190.2-58.31
MENDELSON ALAN CDirector2007-10-26Buy5,00011,000$4.5922.95-59.04
Massey Ian JDirector2007-10-26Buy8,9508,950$4.4439.74-57.66
Nelson CameronVP, Finance & CFO2007-05-10Buy2,0006,000$7.7115.42-75.62
BUTCHOFSKY ROBERTPresident & CEO2007-05-10Buy10,00035,000$7.474-74.59
CLARKE C BOYDDirector2007-05-07Buy10,00013,000$7.3873.8-74.53
Wattier Daniel JVP, Marketing & Sales2007-05-03Buy2,5002,500$7.2218.05-73.96
MENDELSON ALAN CDirector2007-05-03Buy2,0006,000$7.2314.46-74
SCOTT E DUFFDirector2007-01-04Sell30,0000$9.88296.4-80.97
Nelson CameronCFO2006-03-10Buy4,0004,000$7.1828.72-73.82Link
BUTCHOFSKY ROBERTPresident & CEO2006-03-10Buy13,50025,000$7.3198.69-74.28Link
MENDELSON ALAN CDirector2005-08-01Buy1,0004,000$8.538.53-77.96Link
BUTCHOFSKY ROBERTVP Marketing & Sales Planning2005-08-01Sell7,10016,400$8.6961.7-78.37Link
DUNCAN MICHAEL RManager - Atrix Operations2005-05-27Buy240955$10.312.47-81.77Link
AZAB MOHAMMADExec VP-R&D, CMO2005-05-24Buy1,0001,200$10.2810.28-81.71Link
REDENBARGER JAMESVice President Operations2005-05-11Buy400400$11.384.55-83.48Link
HAYES THERESEVP-Invst. Rela. & Corp. Comm.2005-04-29Buy400400$10.524.21-82.13Link
HASTINGS PAUL JPresident & CEO2005-04-29Buy9009,500$10.779.69-82.54Link
MENDELSON ALAN CDirector2005-04-29Buy1,0003,000$10.3810.38-81.89Link
DUNCAN MICHAEL RManager - Atrix Operations2005-03-01Sell7,000715$13.9797.79-86.54Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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