Switch to:

Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
James M. GowerN/A180,6760.2%2005-11-02
Dr. Donald G. Payan,M.D.EVP, Pres. Discovery&Research58,334less than 0.1%2015-06-10
Flynn James EN/A25,000less than 0.1%2010-11-03
Raul R. RodriguezN/A23,607less than 0.1%2004-08-31
Bradford S. GoodwinN/A10,000less than 0.1%2007-08-09
Dr. Robin D.G. Cooper,PhD,D.Sc.N/A9,000less than 0.1%2005-12-07
James H. WelchN/A3,757less than 0.1%2004-09-02
Dr. Walter H. Moos,PhDN/A2,222less than 0.1%2007-06-26
Dr. Elliott B. Grossbard,M.D.N/A2,000less than 0.1%2007-05-29
Dr. Jean Deleage,PhDN/A697less than 0.1%2005-11-02

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
PAYAN DONALD GEVP, Pres. Discovery&Research2015-06-10Sell41,66658,334$3.68153.3-30.9858,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2015-04-01Sell10,00058,334$3.7537.5-32.2758,334 (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$2.222.214.41575 (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$2.222.214.41575 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-09-03Sell20,00068,334$2.5651.2-0.7868,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-02-24Sell20,00088,334$3.7174.2-31.5488,334 (Direct)
BVF PARTNERS L P/IL10% Owner2013-11-19Sell484,6226,962,123$2.641279.4-3.79
6,962,123 (See Explanation of Responses)
BVF PARTNERS L P/IL10% Owner2013-06-07Buy32,7006,962,123$3.47113.5-26.8
6,962,123 (See Explanation of Responses)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2012-09-13Sell4,1511,103$10.4343.3-75.651,103 (Direct)
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-09-12Sell23,3020$10.67248.6-76.19Link
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-09-10Sell51,6980$10.54544.9-75.9Link
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-08-07Sell1,7000$10.6118-76.06Link
PAYAN DONALD GEVP, Pres. Discovery&Research2012-06-19Sell10,000108,334$8.787-70.8108,334 (Direct)
Flynn James E2011-05-26Buy650,0006,742,289$85200-68.2525,000 (Direct)
470,425 (Through Deerfield Special Situations Fund, L.P.)
762,700 (Through Deerfield Special Situations Fund International Limited)
2,279,997 (Through Deerfield Partners, L.P.)
3,204,167 (Through Deerfield International Limited)
Flynn James E2010-11-03Sell7,7116,092,289$7.5558.2-66.36Link
Goodwin Bradford SDirector2007-08-09Buy10,00010,000$9.9399.3-74.42
Grossbard Elliott BSr. VP Medical Development2007-05-29Buy2,0002,000$9.6819.4-73.76
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2005-12-07Buy1,0009,000$8.128.1-68.72Link
DELEAGE JEANDirector2005-07-27Sell171,99711,604$20.333496.7-87.51Link
DELEAGE JEANDirector2005-07-25Sell6,40017,707$20.37130.4-87.53Link
DELEAGE JEANDirector2005-07-21Sell58617,934$20.7512.2-87.76Link
DELEAGE JEANDirector2005-07-20Sell148,04317,955$20.753071.9-87.76Link
VANCE DOLLYVP Intel. Prop.& Gen.Counsel2005-05-10Sell15,0004,385$19.71295.7-87.11Link
VANCE DOLLYVP Intel. Prop.& Gen.Counsel2005-03-30Buy1,0004,385$15.9916-84.12Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2005-02-08Buy5008,000$18.789.4-86.47Link
FRAZIER ALAN DDirector2005-01-25Sell2,33210,905$19.144.5-86.7Link
HENNER DENNISDirector2005-01-05Sell17,2530$23.26401.3-89.08Link
HENNER DENNISDirector2004-11-23Sell868,05517,253$23.4920390.6-89.19Link
SIMON NICHOLAS J IIIDirector2004-11-23Sell868,0550$23.4920390.6-89.19Link
DELEAGE JEANDirector2004-11-05Sell126,05023,207$26.113291.2-90.27Link
DELEAGE JEANDirector2004-10-21Sell177,60027,680$25.054448.9-89.86Link
DELEAGE JEANDirector2004-10-19Sell46,35033,981$26.291218.5-90.34Link
DELEAGE JEANDirector2004-09-30Sell25,6250$24.79635.2-89.75Link
SIMON NICHOLAS J IIIDirector2004-09-17Sell14,9560$32.33483.5-92.14Link
WELCH JAMES HCFO, VP & Secretary
(Click for the stocks that their CFOs have bought)
2004-09-02Sell10,0003,757$20.23202.3-87.44Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-09-01Sell85,0271,687,072$20.751764.3-87.76Link
HENNER DENNISDirector, 10% Owner2004-09-01Sell85,0271,688,641$20.751764.3-87.76Link
EVNIN LUKE10% Owner2004-09-01Sell85,8531,687,072$20.741780.6-87.75Link
MPM BIOVENTURES III QP LP10% Owner2004-09-01Sell85,8531,687,072$20.741780.6-87.75Link
RODRIGUEZ RAUL REVP, COO2004-08-31Sell11,00023,607$20.85229.4-87.82Link
HENNER DENNISDirector, 10% Owner2004-08-20Sell32,4991,773,668$21.83709.5-88.36Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-20Sell33,4211,772,099$21.83729.6-88.36Link
EVNIN LUKE10% Owner2004-08-20Sell32,4991,772,925$21.83709.5-88.36Link
MPM BIOVENTURES III QP LP10% Owner2004-08-20Sell32,4991,772,925$21.83709.5-88.36Link
EVNIN LUKE10% Owner2004-08-18Sell18,9991,805,424$22.26422.9-88.59Link
HENNER DENNISDirector, 10% Owner2004-08-18Sell18,9991,806,167$22.26422.9-88.59Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-18Sell18,9991,805,520$22.26422.9-88.59Link
MPM BIOVENTURES III QP LP10% Owner2004-08-18Sell18,9991,805,424$22.26422.9-88.59Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-13Sell10,0001,824,519$22.3223-88.61Link
EVNIN LUKE10% Owner2004-08-13Sell10,0001,824,423$22.3223-88.61Link
MPM BIOVENTURES III QP LP10% Owner2004-08-13Sell10,0001,824,423$22.3223-88.61Link
HENNER DENNISDirector, 10% Owner2004-08-13Sell10,0001,825,166$22.3223-88.61Link
STEINMETZ MICHAEL10% Owner2004-08-02Sell1,9681,833,597$18.6836.8-86.4Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2004-07-16Buy2,5007,500$11.4628.7-77.84Link
EVNIN LUKE10% Owner2004-07-02Sell7,8471,833,597$14.88116.8-82.93Link
GALAKATOS NICHOLAS10% Owner2004-07-02Sell1,6521,833,597$15.3325.3-83.43Link
GADICKE ANSBERT10% Owner2004-07-02Sell2,4631,833,597$14.5935.9-82.59Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-28Sell2,8771,834,519$15.8345.5-83.95Link
HENNER DENNISDirector, 10% Owner2004-06-28Sell2,8771,835,166$15.8345.5-83.95Link
MPM BIOVENTURES III QP LP10% Owner2004-06-28Sell2,8771,849,800$15.8345.5-83.95Link
EVNIN LUKE10% Owner2004-06-28Sell2,8771,849,800$15.8345.5-83.95Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-25Sell124,3073,336,463$15.661946.6-83.78Link
MPM BIOVENTURES III QP LP10% Owner2004-06-25Sell124,3073,336,463$15.661946.6-83.78Link
HENNER DENNISDirector, 10% Owner2004-06-25Sell124,3073,336,463$15.661946.6-83.78Link
EVNIN LUKE10% Owner2004-06-25Sell124,3073,336,463$15.661946.6-83.78Link
MPM BIOVENTURES III QP LP10% Owner2004-06-23Sell30,1933,460,770$15.51468.3-83.62Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-23Sell30,1933,460,770$15.51468.3-83.62Link
HENNER DENNISDirector, 10% Owner2004-06-23Sell30,1933,460,770$15.51468.3-83.62Link
EVNIN LUKE10% Owner2004-06-23Sell30,1933,460,770$15.51468.3-83.62Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-02Sell2,0303,490,963$1836.5-85.89Link
MPM BIOVENTURES III QP LP10% Owner2004-06-02Sell2,0303,490,963$1836.5-85.89Link
HENNER DENNISDirector, 10% Owner2004-06-02Sell2,0303,490,963$1836.5-85.89Link
EVNIN LUKE10% Owner2004-06-02Sell2,0303,490,963$1836.5-85.89Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-01Sell13,9503,492,993$17.96250.5-85.86Link
MPM BIOVENTURES III QP LP10% Owner2004-06-01Sell13,9503,492,993$17.96250.5-85.86Link
HENNER DENNISDirector, 10% Owner2004-06-01Sell13,9503,492,993$17.96250.5-85.86Link
EVNIN LUKE10% Owner2004-06-01Sell13,9503,492,993$17.96250.5-85.86Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-27Sell26,0153,506,943$17.84464.1-85.76Link
MPM BIOVENTURES III QP LP10% Owner2004-05-27Sell26,0153,506,943$17.84464.1-85.76Link
HENNER DENNISDirector, 10% Owner2004-05-27Sell26,0153,506,943$17.84464.1-85.76Link
EVNIN LUKE10% Owner2004-05-27Sell26,0153,506,943$17.84464.1-85.76Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-24Sell3,3003,532,958$17.3557.3-85.36Link
MPM BIOVENTURES III QP LP10% Owner2004-05-24Sell3,3003,532,958$17.3557.3-85.36Link
EVNIN LUKE10% Owner2004-05-24Sell3,3003,532,958$17.3557.3-85.36Link
HENNER DENNISDirector, 10% Owner2004-05-24Sell3,3003,532,958$17.3557.3-85.36Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2004-05-21Buy5,0005,000$16.6783.4-84.76Link
FRAZIER ALAN DDirector2004-05-20Sell2,333949,280$17.6141.1-85.58Link
HENNER DENNISDirector, 10% Owner2004-05-20Sell139,3133,536,258$17.252403.1-85.28Link
EVNIN LUKE10% Owner2004-05-20Sell139,3133,536,258$17.252403.1-85.28Link
MPM BIOVENTURES III QP LP10% Owner2004-05-20Sell139,3133,536,258$17.252403.1-85.28Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-20Sell139,3133,536,258$17.252403.1-85.28Link
DELEAGE JEANDirector, 10% Owner2004-05-07Sell3,10044,573$21.566.7-88.19Link
ALTA PARTNERS II INC10% Owner2004-05-07Sell3,10044,573$21.566.7-88.19Link
ALTA PARTNERS II INC10% Owner2004-05-03Sell95,20044,573$21.312028.7-88.08Link
DELEAGE JEANDirector, 10% Owner2004-05-03Sell95,20044,573$21.312028.7-88.08Link
DELEAGE JEANDirector, 10% Owner2004-04-30Sell8,40044,573$21.25178.5-88.05Link
ALTA PARTNERS II INC10% Owner2004-04-30Sell8,40044,573$21.25178.5-88.05Link
DELEAGE JEANDirector, 10% Owner2004-04-29Sell42,80044,573$21.25909.5-88.05Link
ALTA PARTNERS II INC10% Owner2004-04-29Sell42,80055,006$21.25909.5-88.05Link
DELEAGE JEANDirector, 10% Owner2004-04-27Sell8,90044,573$21.26189.2-88.05Link
ALTA PARTNERS II INC10% Owner2004-04-27Sell8,90055,962$21.26189.2-88.05Link
DELEAGE JEANDirector, 10% Owner2004-04-23Sell13,10044,573$21.32279.3-88.09Link
ALTA PARTNERS II INC10% Owner2004-04-23Sell13,10044,573$21.32279.3-88.09Link
ALTA PARTNERS II INC10% Owner2004-04-22Sell8,80056,454$21.26187.1-88.05Link
DELEAGE JEANDirector, 10% Owner2004-04-22Sell8,80056,454$21.26187.1-88.05Link
EVNIN LUKE10% Owner2004-04-21Sell158,6983,675,571$20.713286.6-87.74Link
MPM BIOVENTURES III QP LP10% Owner2004-04-21Sell158,6983,675,571$20.713286.6-87.74Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-04-21Sell158,6983,675,571$20.713286.6-87.74Link
HENNER DENNISDirector, 10% Owner2004-04-21Sell158,6983,675,571$20.713286.6-87.74Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-87.26Link
EVNIN LUKE10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-87.26Link
MPM BIOVENTURES III QP LP10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-87.26Link
HENNER DENNISDirector, 10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-87.26Link
DELEAGE JEANDirector, 10% Owner2004-04-07Sell60,30044,573$211266.3-87.9Link
ALTA PARTNERS II INC10% Owner2004-04-07Sell60,30044,573$211266.3-87.9Link
DELEAGE JEANDirector, 10% Owner2004-04-06Sell10,90057,997$21.21231.2-88.02Link
ALTA PARTNERS II INC10% Owner2004-04-06Sell10,90044,573$21.21231.2-88.02Link
FRAZIER ALAN DDirector2004-04-05Sell2,5241,409,965$22.7657.4-88.84Link
ALTA PARTNERS II INC10% Owner2004-03-24Sell7,48744,573$20149.7-87.3Link
DELEAGE JEANDirector, 10% Owner2004-03-24Sell7,48744,573$20149.7-87.3Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-03-19Sell17,3344,150,571$20346.7-87.3Link
HENNER DENNISDirector, 10% Owner2004-03-19Sell17,3344,150,571$20346.7-87.3Link
MPM BIOVENTURES III QP LP10% Owner2004-03-19Sell17,3344,150,571$20346.7-87.3Link
EVNIN LUKE10% Owner2004-02-19Sell17,3344,150,571$20346.7-87.3Link
FRAZIER HEALTHCARE IV LP10% Owner2004-02-19Sell78,4361,223,647$18.81474.6-86.49Link
FRAZIER ALAN DDirector, 10% Owner2004-02-19Sell78,4361,706,726$18.81474.6-86.49Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-02-19Sell172,3734,167,905$203447.5-87.3Link
HENNER DENNISDirector, 10% Owner2004-02-19Sell172,3734,167,905$203447.5-87.3Link
MPM BIOVENTURES III QP LP10% Owner2004-02-19Sell172,3734,350,516$203447.5-87.3Link
MPM BIOEQUITIES MASTER FUND LP10% Owner2004-02-19Sell172,3734,350,516$203447.5-87.3Link
ALTA PARTNERS II INC10% Owner2004-02-19Sell111,69644,573$202233.9-87.3Link
DELEAGE JEANDirector, 10% Owner2004-02-19Sell111,69644,573$202233.9-87.3Link
DELEAGE JEANDirector, 10% Owner2004-02-19Sell111,69644,573$202233.9-87.3Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

To find out why GuruFocus thinks data on insider trade are interesting, please read:
Also See GuruFocus Insider Trade Screener:

Get WordPress Plugins for easy affiliate links on Stock Tickers and Guru Names | Earn affiliate commissions by embedding GuruFocus Charts
GuruFocus Affiliate Program: Earn up to $400 per referral. ( Learn More)

GuruFocus Premium Plus Membership

FEEDBACK