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Top Direct Holders

HolderPositionShares% of Shares
Report Date
James M. GowerN/A180,6760.2%2005-11-02
Dr. Donald G. Payan,M.D.EVP, Pres. Discovery&Research58,334less than 0.1%2015-06-10
Flynn James E25,000less than 0.1%2010-11-03
Raul R. RodriguezEVP, COO23,607less than 0.1%2004-08-31
Bradford S. GoodwinN/A10,000less than 0.1%2007-08-09
Dr. Robin D.G. Cooper,PhD,D.Sc.Sr. V.P. Pharmaceutical Scs.9,000less than 0.1%2005-12-07
James H. WelchCFO, VP & Secretary3,757less than 0.1%2004-09-02
Dr. Walter H. Moos,PhDN/A2,222less than 0.1%2007-06-26
Dr. Elliott B. Grossbard,M.D.N/A2,000less than 0.1%2007-05-29
Dr. Jean Deleage,PhDDirector697less than 0.1%2005-11-02

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
PAYAN DONALD GEVP, Pres. Discovery&Research2015-06-10Sell41,66658,334$3.68153.3-10.658,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2015-04-01Sell10,00058,334$3.7537.5-12.2758,334 (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$ (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$ (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-09-03Sell20,00068,334$2.5651.228.5268,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-02-24Sell20,00088,334$3.7174.2-11.3288,334 (Direct)
BVF PARTNERS L P/IL10% Owner2013-11-19Sell484,6226,962,123$2.641279.424.62
6,962,123 (See Explanation of Responses)
BVF PARTNERS L P/IL10% Owner2013-06-07Buy32,7006,962,123$3.47113.5-5.19
6,962,123 (See Explanation of Responses)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2012-09-13Sell4,1511,103$10.4343.3-68.461,103 (Direct)
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
PAYAN DONALD GEVP, Pres. Discovery&Research2012-06-19Sell10,000108,334$8.787-62.18108,334 (Direct)
Flynn James E2011-05-26Buy650,0006,742,289$85200-58.8825,000 (Direct)
470,425 (Through Deerfield Special Situations Fund, L.P.)
762,700 (Through Deerfield Special Situations Fund International Limited)
2,279,997 (Through Deerfield Partners, L.P.)
3,204,167 (Through Deerfield International Limited)
Flynn James E2010-11-03Sell7,7116,092,289$7.5558.2-56.42Link
Goodwin Bradford SDirector2007-08-09Buy10,00010,000$9.9399.3-66.87
Grossbard Elliott BSr. VP Medical Development2007-05-29Buy2,0002,000$9.6819.4-66.01
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2005-12-07Buy1,0009,000$8.128.1-59.48Link
DELEAGE JEANDirector2005-07-27Sell171,99711,604$20.333496.7-83.82Link
DELEAGE JEANDirector2005-07-25Sell6,40017,707$20.37130.4-83.85Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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