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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Duliege Anne-MarieChief Medical Officer2017-01-03Sell5,0005,000$2.4112.054.155,000 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2016-08-30Sell5,30353,031$421.21-37.25
53,031 (By Family Trust)
PAYAN DONALD GEVP, Pres. Discovery&Research2015-06-10Sell41,66658,334$3.68153.33-31.7958,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2015-04-01Sell10,00058,334$3.7537.5-33.0758,334 (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$2.222.2213.06575 (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$2.222.2213.06575 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-09-03Sell20,00068,334$2.5651.2-1.9568,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-02-24Sell20,00088,334$3.7174.2-32.3588,334 (Direct)
BVF PARTNERS L P/IL10% Owner2013-11-19Sell484,6226,962,123$2.641279.4-4.92
6,962,123 (See Explanation of Responses)
BVF PARTNERS L P/IL10% Owner2013-06-07Buy32,7006,962,123$3.47113.47-27.67
6,962,123 (See Explanation of Responses)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2012-09-13Sell4,1511,103$10.4343.29-75.931,103 (Direct)
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-09-12Sell23,3020$10.67248.63-76.48Link
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-09-10Sell51,6980$10.54544.9-76.19Link
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-08-07Sell1,7000$10.6118.04-76.34Link
PAYAN DONALD GEVP, Pres. Discovery&Research2012-06-19Sell10,000108,334$8.787-71.15108,334 (Direct)
Flynn James E2011-05-26Buy650,0006,742,289$85200-68.6325,000 (Direct)
470,425 (Through Deerfield Special Situations Fund, L.P.)
762,700 (Through Deerfield Special Situations Fund International Limited)
2,279,997 (Through Deerfield Partners, L.P.)
3,204,167 (Through Deerfield International Limited)
Flynn James E2010-11-03Sell7,7116,092,289$7.5558.22-66.75Link
Goodwin Bradford SDirector2007-08-09Buy10,00010,000$9.9399.3-74.72
Grossbard Elliott BSr. VP Medical Development2007-05-29Buy2,0002,000$9.6819.36-74.07
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2005-12-07Buy1,0009,000$8.128.12-69.09Link
DELEAGE JEANDirector2005-07-27Sell171,99711,604$20.333496.7-87.65Link
DELEAGE JEANDirector2005-07-25Sell6,40017,707$20.37130.37-87.68Link
DELEAGE JEANDirector2005-07-21Sell58617,934$20.7512.16-87.9Link
DELEAGE JEANDirector2005-07-20Sell148,04317,955$20.753071.89-87.9Link
VANCE DOLLYVP Intel. Prop.& Gen.Counsel2005-05-10Sell15,0004,385$19.71295.65-87.27Link
VANCE DOLLYVP Intel. Prop.& Gen.Counsel2005-03-30Buy1,0004,385$15.9915.99-84.3Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2005-02-08Buy5008,000$18.789.39-86.63Link
FRAZIER ALAN DDirector2005-01-25Sell2,33210,905$19.144.54-86.86Link
HENNER DENNISDirector2005-01-05Sell17,2530$23.26401.3-89.21Link
HENNER DENNISDirector2004-11-23Sell868,05517,253$23.4920390.61-89.31Link
SIMON NICHOLAS J IIIDirector2004-11-23Sell868,0550$23.4920390.61-89.31Link
DELEAGE JEANDirector2004-11-05Sell126,05023,207$26.113291.17-90.39Link
DELEAGE JEANDirector2004-10-21Sell177,60027,680$25.054448.88-89.98Link
DELEAGE JEANDirector2004-10-19Sell46,35033,981$26.291218.54-90.45Link
DELEAGE JEANDirector2004-09-30Sell25,6250$24.79635.24-89.87Link
SIMON NICHOLAS J IIIDirector2004-09-17Sell14,9560$32.33483.53-92.24Link
WELCH JAMES HCFO, VP & Secretary
(Click for the stocks that their CFOs have bought)
2004-09-02Sell10,0003,757$20.23202.3-87.59Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-09-01Sell85,0271,687,072$20.751764.31-87.9Link
HENNER DENNISDirector, 10% Owner2004-09-01Sell85,0271,688,641$20.751764.31-87.9Link
EVNIN LUKE10% Owner2004-09-01Sell85,8531,687,072$20.741780.59-87.9Link
MPM BIOVENTURES III QP LP10% Owner2004-09-01Sell85,8531,687,072$20.741780.59-87.9Link
RODRIGUEZ RAUL REVP, COO2004-08-31Sell11,00023,607$20.85229.35-87.96Link
HENNER DENNISDirector, 10% Owner2004-08-20Sell32,4991,773,668$21.83709.45-88.5Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-20Sell33,4211,772,099$21.83729.58-88.5Link
EVNIN LUKE10% Owner2004-08-20Sell32,4991,772,925$21.83709.45-88.5Link
MPM BIOVENTURES III QP LP10% Owner2004-08-20Sell32,4991,772,925$21.83709.45-88.5Link
EVNIN LUKE10% Owner2004-08-18Sell18,9991,805,424$22.26422.92-88.72Link
HENNER DENNISDirector, 10% Owner2004-08-18Sell18,9991,806,167$22.26422.92-88.72Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-18Sell18,9991,805,520$22.26422.92-88.72Link
MPM BIOVENTURES III QP LP10% Owner2004-08-18Sell18,9991,805,424$22.26422.92-88.72Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-13Sell10,0001,824,519$22.3223-88.74Link
EVNIN LUKE10% Owner2004-08-13Sell10,0001,824,423$22.3223-88.74Link
MPM BIOVENTURES III QP LP10% Owner2004-08-13Sell10,0001,824,423$22.3223-88.74Link
HENNER DENNISDirector, 10% Owner2004-08-13Sell10,0001,825,166$22.3223-88.74Link
STEINMETZ MICHAEL10% Owner2004-08-02Sell1,9681,833,597$18.6836.76-86.56Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2004-07-16Buy2,5007,500$11.4628.65-78.1Link
EVNIN LUKE10% Owner2004-07-02Sell7,8471,833,597$14.88116.76-83.13Link
GALAKATOS NICHOLAS10% Owner2004-07-02Sell1,6521,833,597$15.3325.33-83.63Link
GADICKE ANSBERT10% Owner2004-07-02Sell2,4631,833,597$14.5935.94-82.8Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-28Sell2,8771,834,519$15.8345.54-84.14Link
HENNER DENNISDirector, 10% Owner2004-06-28Sell2,8771,835,166$15.8345.54-84.14Link
MPM BIOVENTURES III QP LP10% Owner2004-06-28Sell2,8771,849,800$15.8345.54-84.14Link
EVNIN LUKE10% Owner2004-06-28Sell2,8771,849,800$15.8345.54-84.14Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-83.97Link
MPM BIOVENTURES III QP LP10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-83.97Link
HENNER DENNISDirector, 10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-83.97Link
EVNIN LUKE10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-83.97Link
MPM BIOVENTURES III QP LP10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-83.82Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-83.82Link
HENNER DENNISDirector, 10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-83.82Link
EVNIN LUKE10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-83.82Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-02Sell2,0303,490,963$1836.54-86.06Link
MPM BIOVENTURES III QP LP10% Owner2004-06-02Sell2,0303,490,963$1836.54-86.06Link
HENNER DENNISDirector, 10% Owner2004-06-02Sell2,0303,490,963$1836.54-86.06Link
EVNIN LUKE10% Owner2004-06-02Sell2,0303,490,963$1836.54-86.06Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-86.02Link
MPM BIOVENTURES III QP LP10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-86.02Link
HENNER DENNISDirector, 10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-86.02Link
EVNIN LUKE10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-86.02Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-85.93Link
MPM BIOVENTURES III QP LP10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-85.93Link
HENNER DENNISDirector, 10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-85.93Link
EVNIN LUKE10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-85.93Link
EVNIN LUKE10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-85.53Link
HENNER DENNISDirector, 10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-85.53Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-85.53Link
MPM BIOVENTURES III QP LP10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-85.53Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2004-05-21Buy5,0005,000$16.6783.35-84.94Link
FRAZIER ALAN DDirector2004-05-20Sell2,333949,280$17.6141.08-85.75Link
HENNER DENNISDirector, 10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-85.45Link
EVNIN LUKE10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-85.45Link
MPM BIOVENTURES III QP LP10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-85.45Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-85.45Link
DELEAGE JEANDirector, 10% Owner2004-05-07Sell3,10044,573$21.566.65-88.33Link
ALTA PARTNERS II INC10% Owner2004-05-07Sell3,10044,573$21.566.65-88.33Link
ALTA PARTNERS II INC10% Owner2004-05-03Sell95,20044,573$21.312028.71-88.22Link
DELEAGE JEANDirector, 10% Owner2004-05-03Sell95,20044,573$21.312028.71-88.22Link
DELEAGE JEANDirector, 10% Owner2004-04-30Sell8,40044,573$21.25178.5-88.19Link
ALTA PARTNERS II INC10% Owner2004-04-30Sell8,40044,573$21.25178.5-88.19Link
DELEAGE JEANDirector, 10% Owner2004-04-29Sell42,80044,573$21.25909.5-88.19Link
ALTA PARTNERS II INC10% Owner2004-04-29Sell42,80055,006$21.25909.5-88.19Link
DELEAGE JEANDirector, 10% Owner2004-04-27Sell8,90044,573$21.26189.21-88.19Link
ALTA PARTNERS II INC10% Owner2004-04-27Sell8,90055,962$21.26189.21-88.19Link
DELEAGE JEANDirector, 10% Owner2004-04-23Sell13,10044,573$21.32279.29-88.23Link
ALTA PARTNERS II INC10% Owner2004-04-23Sell13,10044,573$21.32279.29-88.23Link
ALTA PARTNERS II INC10% Owner2004-04-22Sell8,80056,454$21.26187.09-88.19Link
DELEAGE JEANDirector, 10% Owner2004-04-22Sell8,80056,454$21.26187.09-88.19Link
EVNIN LUKE10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-87.88Link
MPM BIOVENTURES III QP LP10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-87.88Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-87.88Link
HENNER DENNISDirector, 10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-87.88Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-87.41Link
EVNIN LUKE10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-87.41Link
MPM BIOVENTURES III QP LP10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-87.41Link
HENNER DENNISDirector, 10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-87.41Link
DELEAGE JEANDirector, 10% Owner2004-04-07Sell60,30044,573$211266.3-88.05Link
ALTA PARTNERS II INC10% Owner2004-04-07Sell60,30044,573$211266.3-88.05Link
DELEAGE JEANDirector, 10% Owner2004-04-06Sell10,90057,997$21.21231.19-88.17Link
ALTA PARTNERS II INC10% Owner2004-04-06Sell10,90044,573$21.21231.19-88.17Link
FRAZIER ALAN DDirector2004-04-05Sell2,5241,409,965$22.7657.45-88.97Link
ALTA PARTNERS II INC10% Owner2004-03-24Sell7,48744,573$20149.74-87.45Link
DELEAGE JEANDirector, 10% Owner2004-03-24Sell7,48744,573$20149.74-87.45Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-03-19Sell17,3344,150,571$20346.68-87.45Link
HENNER DENNISDirector, 10% Owner2004-03-19Sell17,3344,150,571$20346.68-87.45Link
MPM BIOVENTURES III QP LP10% Owner2004-03-19Sell17,3344,150,571$20346.68-87.45Link
EVNIN LUKE10% Owner2004-02-19Sell17,3344,150,571$20346.68-87.45Link
FRAZIER HEALTHCARE IV LP10% Owner2004-02-19Sell78,4361,223,647$18.81474.6-86.65Link
FRAZIER ALAN DDirector, 10% Owner2004-02-19Sell78,4361,706,726$18.81474.6-86.65Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-02-19Sell172,3734,167,905$203447.46-87.45Link
HENNER DENNISDirector, 10% Owner2004-02-19Sell172,3734,167,905$203447.46-87.45Link
MPM BIOVENTURES III QP LP10% Owner2004-02-19Sell172,3734,350,516$203447.46-87.45Link
MPM BIOEQUITIES MASTER FUND LP10% Owner2004-02-19Sell172,3734,350,516$203447.46-87.45Link
ALTA PARTNERS II INC10% Owner2004-02-19Sell111,69644,573$202233.92-87.45Link
DELEAGE JEANDirector, 10% Owner2004-02-19Sell111,69644,573$202233.92-87.45Link
DELEAGE JEANDirector, 10% Owner2004-02-19Sell111,69644,573$202233.92-87.45Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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