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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Duliege Anne-MarieChief Medical Officer2017-01-03Sell5,0005,000$2.4112.0514.945,000 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2016-08-30Sell5,30353,031$421.21-30.75
53,031 (By Family Trust)
PAYAN DONALD GEVP, Pres. Discovery&Research2015-06-10Sell41,66658,334$3.68153.33-24.7358,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2015-04-01Sell10,00058,334$3.7537.5-26.1358,334 (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$2.222.2224.77575 (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$2.222.2224.77575 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-09-03Sell20,00068,334$2.5651.28.268,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-02-24Sell20,00088,334$3.7174.2-25.3488,334 (Direct)
BVF PARTNERS L P/IL10% Owner2013-11-19Sell484,6226,962,123$2.641279.44.92
6,962,123 (See Explanation of Responses)
BVF PARTNERS L P/IL10% Owner2013-06-07Buy32,7006,962,123$3.47113.47-20.17
6,962,123 (See Explanation of Responses)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2012-09-13Sell4,1511,103$10.4343.29-73.441,103 (Direct)
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-09-12Sell23,3020$10.67248.63-74.04Link
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-09-10Sell51,6980$10.54544.9-73.72Link
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-08-07Sell1,7000$10.6118.04-73.89Link
PAYAN DONALD GEVP, Pres. Discovery&Research2012-06-19Sell10,000108,334$8.787-68.16108,334 (Direct)
Flynn James E2011-05-26Buy650,0006,742,289$85200-65.3825,000 (Direct)
470,425 (Through Deerfield Special Situations Fund, L.P.)
762,700 (Through Deerfield Special Situations Fund International Limited)
2,279,997 (Through Deerfield Partners, L.P.)
3,204,167 (Through Deerfield International Limited)
Flynn James E2010-11-03Sell7,7116,092,289$7.5558.22-63.31Link
Goodwin Bradford SDirector2007-08-09Buy10,00010,000$9.9399.3-72.1
Grossbard Elliott BSr. VP Medical Development2007-05-29Buy2,0002,000$9.6819.36-71.38
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2005-12-07Buy1,0009,000$8.128.12-65.89Link
DELEAGE JEANDirector2005-07-27Sell171,99711,604$20.333496.7-86.37Link
DELEAGE JEANDirector2005-07-25Sell6,40017,707$20.37130.37-86.4Link
DELEAGE JEANDirector2005-07-21Sell58617,934$20.7512.16-86.65Link
DELEAGE JEANDirector2005-07-20Sell148,04317,955$20.753071.89-86.65Link
VANCE DOLLYVP Intel. Prop.& Gen.Counsel2005-05-10Sell15,0004,385$19.71295.65-85.95Link
VANCE DOLLYVP Intel. Prop.& Gen.Counsel2005-03-30Buy1,0004,385$15.9915.99-82.68Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2005-02-08Buy5008,000$18.789.39-85.25Link
FRAZIER ALAN DDirector2005-01-25Sell2,33210,905$19.144.54-85.5Link
HENNER DENNISDirector2005-01-05Sell17,2530$23.26401.3-88.09Link
HENNER DENNISDirector2004-11-23Sell868,05517,253$23.4920390.61-88.21Link
SIMON NICHOLAS J IIIDirector2004-11-23Sell868,0550$23.4920390.61-88.21Link
DELEAGE JEANDirector2004-11-05Sell126,05023,207$26.113291.17-89.39Link
DELEAGE JEANDirector2004-10-21Sell177,60027,680$25.054448.88-88.94Link
DELEAGE JEANDirector2004-10-19Sell46,35033,981$26.291218.54-89.46Link
DELEAGE JEANDirector2004-09-30Sell25,6250$24.79635.24-88.83Link
SIMON NICHOLAS J IIIDirector2004-09-17Sell14,9560$32.33483.53-91.43Link
WELCH JAMES HCFO, VP & Secretary
(Click for the stocks that their CFOs have bought)
2004-09-02Sell10,0003,757$20.23202.3-86.31Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-09-01Sell85,0271,687,072$20.751764.31-86.65Link
HENNER DENNISDirector, 10% Owner2004-09-01Sell85,0271,688,641$20.751764.31-86.65Link
EVNIN LUKE10% Owner2004-09-01Sell85,8531,687,072$20.741780.59-86.64Link
MPM BIOVENTURES III QP LP10% Owner2004-09-01Sell85,8531,687,072$20.741780.59-86.64Link
RODRIGUEZ RAUL REVP, COO2004-08-31Sell11,00023,607$20.85229.35-86.71Link
HENNER DENNISDirector, 10% Owner2004-08-20Sell32,4991,773,668$21.83709.45-87.31Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-20Sell33,4211,772,099$21.83729.58-87.31Link
EVNIN LUKE10% Owner2004-08-20Sell32,4991,772,925$21.83709.45-87.31Link
MPM BIOVENTURES III QP LP10% Owner2004-08-20Sell32,4991,772,925$21.83709.45-87.31Link
EVNIN LUKE10% Owner2004-08-18Sell18,9991,805,424$22.26422.92-87.56Link
HENNER DENNISDirector, 10% Owner2004-08-18Sell18,9991,806,167$22.26422.92-87.56Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-18Sell18,9991,805,520$22.26422.92-87.56Link
MPM BIOVENTURES III QP LP10% Owner2004-08-18Sell18,9991,805,424$22.26422.92-87.56Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-13Sell10,0001,824,519$22.3223-87.58Link
EVNIN LUKE10% Owner2004-08-13Sell10,0001,824,423$22.3223-87.58Link
MPM BIOVENTURES III QP LP10% Owner2004-08-13Sell10,0001,824,423$22.3223-87.58Link
HENNER DENNISDirector, 10% Owner2004-08-13Sell10,0001,825,166$22.3223-87.58Link
STEINMETZ MICHAEL10% Owner2004-08-02Sell1,9681,833,597$18.6836.76-85.17Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2004-07-16Buy2,5007,500$11.4628.65-75.83Link
EVNIN LUKE10% Owner2004-07-02Sell7,8471,833,597$14.88116.76-81.38Link
GALAKATOS NICHOLAS10% Owner2004-07-02Sell1,6521,833,597$15.3325.33-81.93Link
GADICKE ANSBERT10% Owner2004-07-02Sell2,4631,833,597$14.5935.94-81.01Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-28Sell2,8771,834,519$15.8345.54-82.5Link
HENNER DENNISDirector, 10% Owner2004-06-28Sell2,8771,835,166$15.8345.54-82.5Link
MPM BIOVENTURES III QP LP10% Owner2004-06-28Sell2,8771,849,800$15.8345.54-82.5Link
EVNIN LUKE10% Owner2004-06-28Sell2,8771,849,800$15.8345.54-82.5Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-82.31Link
MPM BIOVENTURES III QP LP10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-82.31Link
HENNER DENNISDirector, 10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-82.31Link
EVNIN LUKE10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-82.31Link
MPM BIOVENTURES III QP LP10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-82.14Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-82.14Link
HENNER DENNISDirector, 10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-82.14Link
EVNIN LUKE10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-82.14Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-02Sell2,0303,490,963$1836.54-84.61Link
MPM BIOVENTURES III QP LP10% Owner2004-06-02Sell2,0303,490,963$1836.54-84.61Link
HENNER DENNISDirector, 10% Owner2004-06-02Sell2,0303,490,963$1836.54-84.61Link
EVNIN LUKE10% Owner2004-06-02Sell2,0303,490,963$1836.54-84.61Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-84.58Link
MPM BIOVENTURES III QP LP10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-84.58Link
HENNER DENNISDirector, 10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-84.58Link
EVNIN LUKE10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-84.58Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-84.47Link
MPM BIOVENTURES III QP LP10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-84.47Link
HENNER DENNISDirector, 10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-84.47Link
EVNIN LUKE10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-84.47Link
EVNIN LUKE10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-84.03Link
HENNER DENNISDirector, 10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-84.03Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-84.03Link
MPM BIOVENTURES III QP LP10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-84.03Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2004-05-21Buy5,0005,000$16.6783.35-83.38Link
FRAZIER ALAN DDirector2004-05-20Sell2,333949,280$17.6141.08-84.27Link
HENNER DENNISDirector, 10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-83.94Link
EVNIN LUKE10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-83.94Link
MPM BIOVENTURES III QP LP10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-83.94Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-83.94Link
DELEAGE JEANDirector, 10% Owner2004-05-07Sell3,10044,573$21.566.65-87.12Link
ALTA PARTNERS II INC10% Owner2004-05-07Sell3,10044,573$21.566.65-87.12Link
ALTA PARTNERS II INC10% Owner2004-05-03Sell95,20044,573$21.312028.71-87Link
DELEAGE JEANDirector, 10% Owner2004-05-03Sell95,20044,573$21.312028.71-87Link
DELEAGE JEANDirector, 10% Owner2004-04-30Sell8,40044,573$21.25178.5-86.96Link
ALTA PARTNERS II INC10% Owner2004-04-30Sell8,40044,573$21.25178.5-86.96Link
DELEAGE JEANDirector, 10% Owner2004-04-29Sell42,80044,573$21.25909.5-86.96Link
ALTA PARTNERS II INC10% Owner2004-04-29Sell42,80055,006$21.25909.5-86.96Link
DELEAGE JEANDirector, 10% Owner2004-04-27Sell8,90044,573$21.26189.21-86.97Link
ALTA PARTNERS II INC10% Owner2004-04-27Sell8,90055,962$21.26189.21-86.97Link
DELEAGE JEANDirector, 10% Owner2004-04-23Sell13,10044,573$21.32279.29-87.01Link
ALTA PARTNERS II INC10% Owner2004-04-23Sell13,10044,573$21.32279.29-87.01Link
ALTA PARTNERS II INC10% Owner2004-04-22Sell8,80056,454$21.26187.09-86.97Link
DELEAGE JEANDirector, 10% Owner2004-04-22Sell8,80056,454$21.26187.09-86.97Link
EVNIN LUKE10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-86.62Link
MPM BIOVENTURES III QP LP10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-86.62Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-86.62Link
HENNER DENNISDirector, 10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-86.62Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-86.1Link
EVNIN LUKE10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-86.1Link
MPM BIOVENTURES III QP LP10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-86.1Link
HENNER DENNISDirector, 10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-86.1Link
DELEAGE JEANDirector, 10% Owner2004-04-07Sell60,30044,573$211266.3-86.81Link
ALTA PARTNERS II INC10% Owner2004-04-07Sell60,30044,573$211266.3-86.81Link
DELEAGE JEANDirector, 10% Owner2004-04-06Sell10,90057,997$21.21231.19-86.94Link
ALTA PARTNERS II INC10% Owner2004-04-06Sell10,90044,573$21.21231.19-86.94Link
FRAZIER ALAN DDirector2004-04-05Sell2,5241,409,965$22.7657.45-87.83Link
ALTA PARTNERS II INC10% Owner2004-03-24Sell7,48744,573$20149.74-86.15Link
DELEAGE JEANDirector, 10% Owner2004-03-24Sell7,48744,573$20149.74-86.15Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-03-19Sell17,3344,150,571$20346.68-86.15Link
HENNER DENNISDirector, 10% Owner2004-03-19Sell17,3344,150,571$20346.68-86.15Link
MPM BIOVENTURES III QP LP10% Owner2004-03-19Sell17,3344,150,571$20346.68-86.15Link
EVNIN LUKE10% Owner2004-02-19Sell17,3344,150,571$20346.68-86.15Link
FRAZIER HEALTHCARE IV LP10% Owner2004-02-19Sell78,4361,223,647$18.81474.6-85.27Link
FRAZIER ALAN DDirector, 10% Owner2004-02-19Sell78,4361,706,726$18.81474.6-85.27Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-02-19Sell172,3734,167,905$203447.46-86.15Link
HENNER DENNISDirector, 10% Owner2004-02-19Sell172,3734,167,905$203447.46-86.15Link
MPM BIOVENTURES III QP LP10% Owner2004-02-19Sell172,3734,350,516$203447.46-86.15Link
MPM BIOEQUITIES MASTER FUND LP10% Owner2004-02-19Sell172,3734,350,516$203447.46-86.15Link
ALTA PARTNERS II INC10% Owner2004-02-19Sell111,69644,573$202233.92-86.15Link
DELEAGE JEANDirector, 10% Owner2004-02-19Sell111,69644,573$202233.92-86.15Link
DELEAGE JEANDirector, 10% Owner2004-02-19Sell111,69644,573$202233.92-86.15Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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