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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Joseph S. PodolskiCEO77,4220.32%2016-01-06
Louis Ploth,JrN/A41,0170.17%2008-10-07
Ms. Katherine A. AndersonCFO23,8750.1%2016-01-27
Dr. Ronald Wiehle,PhDN/A22,016less than 0.1%2007-01-04
Daniel F. CainDirector11,000less than 0.1%2014-01-10
Van As Andre Md, PhdN/A10,000less than 0.1%2007-01-11
Dr. Joachim F. WernickeN/A10,000less than 0.1%2016-01-25
Dr. Michael WyllieN/A9,359less than 0.1%2012-10-29
Dr. John C. Reed,M.D.,PhDN/A3,846less than 0.1%2008-10-02
Nola E. Masterson,PhDDirector3,355less than 0.1%2012-09-12

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
PODOLSKI JOSEPHPresident and CEO
(Click for the stocks that their CEOs have bought)
2016-01-07Buy11,67777,422$1.1813.8-12.7177,422 (Direct)
Anderson KatherineCFO2014-11-12Buy3,50011,875$9.4132.9-89.0511,875 (Direct)
PODOLSKI JOSEPHPresident and CEO2014-11-12Buy4,70065,745$9.4244.3-89.0765,745 (Direct)
Masterson Nola EDirector2014-09-15Buy2003,305$14.342.9-92.82
3,305 (By Science Futures LLC)
PODOLSKI JOSEPHPresident and CEO2014-08-14Buy2,10061,045$13.9129.2-92.661,045 (Direct)
Anderson KatherineCFO2014-08-14Buy2,0008,375$13.8527.7-92.568,375 (Direct)
CAIN DANIEL FDirector2013-11-12Buy5001,000$14.977.5-93.121,000 (Direct)
PODOLSKI JOSEPHPresident and CEO2013-10-25Buy3,00058,945$18.0354.1-94.2958,945 (Direct)
Anderson KatherineCFO2013-10-25Buy1,0006,375$17.917.9-94.256,375 (Direct)
Anderson KatherineCFO2013-10-10Buy1,0005,375$23.7723.8-95.675,375 (Direct)
Anderson KatherineCFO2013-02-01Buy1,0004,375$11.8911.9-91.344,375 (Direct)
PERCEPTIVE ADVISORS LLC10% Owner2012-05-14Buy59,5002,862,560$7.38439.1-86.04
2,862,560 (See Footnotes(F1,F2))
PERCEPTIVE ADVISORS LLC10% Owner2012-05-11Buy170,0002,803,060$6.351079.5-83.78
2,803,060 (See Footnotes(F1,F2))
PERCEPTIVE ADVISORS LLC10% Owner2012-05-10Buy325,0002,633,060$4.821566.5-78.63
2,633,060 (See Footnotes(F1,F2))
Anderson KatherineCFO2012-04-13Buy3,0003,375$3.8611.6-73.323,375 (Direct)
PODOLSKI JOSEPHPresident and CEO2012-03-05Buy5,00055,945$3.9920-74.1955,945 (Direct)
PERCEPTIVE ADVISORS LLC10% Owner2011-08-19Buy725,6002,308,060$5.433940-81.03
2,308,060 (See Footnotes(F1,F2,F3))
PERCEPTIVE ADVISORS LLC10% Owner2011-08-12Buy8001,582,460$7.56-86.27
1,582,460 (See Footnotes(F1,F2,F3))
PERCEPTIVE ADVISORS LLC10% Owner2011-08-09Buy23,6003,159,520$7.5177-86.27
1,577,860 (See Footnotes(F1,F2,F3))
1,581,660 (See footnotes(F1,F2,F3))
PERCEPTIVE ADVISORS LLC10% Owner2011-03-16Buy86,5000$5.21450.7-80.23Link
PERCEPTIVE ADVISORS LLC10% Owner2011-03-07Buy30,0000$6.47194.1-84.08Link
PERCEPTIVE ADVISORS LLC10% Owner2011-03-01Buy50,0001,441,560$4.62231-77.71
1,441,560 (See Footnotes(F1,F2))
PERCEPTIVE ADVISORS LLC10% Owner2011-02-28Buy88,2730$4.46393.7-76.91Link
PERCEPTIVE ADVISORS LLC10% Owner2011-02-25Buy158,9220$4.4699.3-76.59Link
Masterson Nola EDirector2010-07-07Buy1,2502,750$0.30.4-14.17Link
Masterson Nola EDirector2010-06-24Buy1,2501,500$0.410.5-37.2Link
PODOLSKI JOSEPHPresident and CEO2010-06-22Buy8,12570,891$0.443.6-41.48Link
Efficacy Capital, Ltd.10% Owner2009-12-21Sell39,201638,058$0.6726.3-61.57Link
Efficacy Capital, Ltd.10% Owner2009-12-15Sell96,525677,259$0.6865.6-62.13Link
Efficacy Capital, Ltd.10% Owner2009-12-02Sell135,250773,784$0.794.7-63.21Link
Efficacy Capital, Ltd.10% Owner2009-11-23Sell164,000909,034$0.72118.1-64.24Link
PODOLSKI JOSEPHCEO2009-03-05Buy1,00029,820$6.416.4-95.98
Harder Jeffrey RDirector2008-11-18Buy100100$9.791-97.37
Efficacy Capital, Ltd.10% Owner2008-10-31Buy2,8251,073,034$7.7621.9-96.68
Lappe MarkDirector, 10% Owner2008-10-31Buy2,8251,073,034$7.7621.9-96.68
Efficacy Capital, Ltd.10% Owner2008-10-29Buy8,5731,070,209$6.9459.5-96.29
Lappe MarkDirector, 10% Owner2008-10-29Buy8,5731,070,209$6.9459.5-96.29
Efficacy Capital, Ltd.10% Owner2008-10-27Buy15,5341,061,636$6.72104.4-96.17
Lappe MarkDirector, 10% Owner2008-10-27Buy15,5341,061,636$6.72104.4-96.17
Harder Jeffrey RDirector2008-10-22Buy5002,625$6.473.2-96.02
Lappe MarkDirector, 10% Owner2008-10-17Buy7,5001,046,103$6.4248.2-95.99
Efficacy Capital, Ltd.10% Owner2008-10-17Buy7,5001,046,103$6.4248.2-95.99
Masterson Nola EDirector2008-10-14Buy100250$70.7-96.32
Efficacy Capital, Ltd.10% Owner2008-10-13Buy7,5751,038,603$6.5249.4-96.05
Lappe MarkDirector, 10% Owner2008-10-13Buy7,5751,038,603$6.5249.4-96.05
PLOTH LOUIS JRVP & CFO, Director2008-10-07Buy70010,254$7.155-96.4
PODOLSKI JOSEPHPresident and CEO, Director2008-10-07Buy1,10028,820$7.147.9-96.39
Efficacy Capital, Ltd.10% Owner2008-10-02Buy461,5391,031,028$6.53000-96.04
REED JOHN CDirector2008-10-02Buy6,2506,250$6.540.6-96.04
Lappe MarkDirector, 10% Owner2008-10-02Buy461,5391,031,028$6.53000-96.04
REED JOHN CDirector2008-10-02Buy962962$6.56.2-96.04
Harder Jeffrey RDirector2008-05-23Buy2502,125$9.142.3-97.18
FOURCROY JEAN L MD PHD MPHDirector2008-05-20Buy150150$9.341.4-97.24
PLOTH LOUIS JRVP & CFO, Director2008-04-22Buy1259,554$8.771.1-97.06
PODOLSKI JOSEPHPresident and CEO, Director2008-04-16Buy37527,720$8.863.3-97.09
PLOTH LOUIS JRVP & CFO, Director2008-04-16Buy5009,429$8.754.4-97.06
PODOLSKI JOSEPHPresident and CEO, Director2008-04-16Buy37527,720$8.863.3-97.09
Harder Jeffrey RDirector2008-04-15Buy2501,875$8.512.1-96.97
PODOLSKI JOSEPHPresident and CEO, Director2008-04-09Buy25027,345$92.3-97.14
Efficacy Capital, Ltd.10% Owner2008-03-27Sell75,514569,489$9.21695.5-97.2
Efficacy Capital, Ltd.10% Owner2008-03-12Buy12,500645,003$8.5106.3-96.97
Efficacy Capital, Ltd.10% Owner2008-03-10Buy18,625632,503$8.54159.1-96.98
Harder Jeffrey RDirector2008-03-03Buy1251,625$8.541.1-96.98
Efficacy Capital, Ltd.10% Owner2008-02-29Buy12,500613,878$8.3103.8-96.9
Harder Jeffrey RDirector2008-02-26Buy1251,500$8.81.1-97.07
Masterson Nola EDirector2008-02-04Buy125150$8.61.1-97.01
Harder Jeffrey RDirector2008-01-24Buy2501,375$8.92.2-97.11
Efficacy Capital, Ltd.10% Owner2008-01-07Buy8,625601,378$9.0377.9-97.15
Efficacy Capital, Ltd.10% Owner2007-12-31Buy31,025592,753$9.37290.7-97.25
PODOLSKI JOSEPHPresident and CEO, Director2007-12-31Buy25027,095$9.362.3-97.25
Efficacy Capital, Ltd.10% Owner2007-12-21Buy25,000561,728$9.45236.3-97.28
Efficacy Capital, Ltd.10% Owner2007-12-19Buy21,4000$9.82210.1-97.38
Efficacy Capital, Ltd.10% Owner2007-12-14Buy40,025515,328$9.51380.6-97.29
Efficacy Capital, Ltd.10% Owner2007-12-06Buy24,825475,303$8.05199.8-96.8
Efficacy Capital, Ltd.10% Owner2007-12-04Buy30,375450,478$8.06244.8-96.81
Efficacy Capital, Ltd.10% Owner2007-10-25Buy54,2500$12.44674.9-97.93
PODOLSKI JOSEPHPresident and CEO, Director2007-10-25Buy25026,845$12.663.2-97.97
van As Andre MD, PhDChief Medical Officer2007-01-11Buy5002,500$12.26.1-97.89
van As Andre MD, PhDChief Medical Officer2006-12-26Buy103103$11.851.2-97.83
van As Andre MD, PhDChief Medical Officer2006-12-19Buy5002,000$7.083.5-96.36
PLOTH LOUIS JRVP & CFO, Director2006-11-01Buy2318,412$7.951.8-96.76
PODOLSKI JOSEPHPresident and CEO, Director2006-10-27Buy50025,720$8.184.1-96.85
CAIN DANIEL FDirector2006-07-27Buy500500$8.344.2-96.91Link
Harder Jeffrey RDirector2006-07-06Buy2501,356$7.952-96.76Link
PODOLSKI JOSEPHPresident and CEO2006-05-05Buy25025,220$10.992.7-97.66Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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