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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Marvin S. Hausman,M.D.N/A2,389,9392.81%2005-01-11
Dr. Christopher M. Starr,PhDDirector706,0650.83%2015-05-19
Dr. Todd C. Zankel,PhDChief Scientific Officer651,8660.77%2012-09-04
Gosse B. Bruinsma,M.D.N/A535,5000.63%2004-12-17
Dr. William T. Comer,PhDN/A175,2560.21%2007-05-18
Louis G. CornacchiaN/A171,9330.2%2004-12-17
Mr. Steven B. RatoffN/A81,2080.1%2006-12-26
Dr. Suzanne L. BruhnDirector48,437less than 0.1%2015-09-09
Ms. Julie Anne SmithN/A37,950less than 0.1%2014-12-03
Thomas (Ted) E. DaleyChief Business Officer34,719less than 0.1%2015-06-18

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Bruhn Suzanne LouiseDirector2015-09-09Sell18,25848,437$12.47227.7-69.1348,437 (Direct)
Anderson RaymondDirector2015-09-02Sell4,9166,695$12.5161.5-69.226,695 (Direct)
Anderson RaymondDirector2015-08-31Sell8,0846,695$12.52101.2-69.256,695 (Direct)
Keltner LlewDirector2015-07-01Sell50,0006,695$16.05802.5-76.016,695 (Direct)
Daley Thomas EChief Business Officer2015-06-18Sell35,00034,719$15525-74.3334,719 (Direct)
Bruhn Suzanne LouiseDirector2015-06-10Sell30,0006,695$13.45403.5-71.386,695 (Direct)
Daley Thomas EChief Business Officer2015-05-20Sell10,00064,719$12120-67.9264,719 (Direct)
FRANKLIN RICHARD LDirector2015-05-04Sell10,0001,674$9.6196.1-59.941,674 (Direct)
FRANKLIN RICHARD LDirector2015-04-02Sell10,0001,674$10.37103.7-62.871,674 (Direct)
Anderson RaymondDirector2015-03-24Sell21,6191,674$12259.4-67.921,674 (Direct)
STARR CHRISTOPHER MDirector2015-03-23Sell20,033701,044$11.62232.8-66.87701,044 (Direct)
STARR CHRISTOPHER MDirector2015-03-16Sell30,021701,044$11.71351.5-67.12701,044 (Direct)
SAGER ERICHDirector2015-03-05Sell25,0004,005$10.71267.8-64.054,005 (Direct)
FRANKLIN RICHARD LDirector2015-03-02Sell10,0000$9.1891.8-58.06Link
STARR CHRISTOPHER MDirector2015-02-24Sell30,000701,044$9.52285.6-59.56701,044 (Direct)
STARR CHRISTOPHER MDirector2015-02-17Sell30,000701,044$9.37281.1-58.91701,044 (Direct)
FRANKLIN RICHARD LDirector2015-02-02Sell7,1090$9.265.4-58.15Link
STARR CHRISTOPHER MDirector2015-01-22Sell30,000699,370$9.45283.5-59.26699,370 (Direct)
STARR CHRISTOPHER MDirector2015-01-15Sell30,000699,370$9.73291.9-60.43699,370 (Direct)
STARR CHRISTOPHER MCEO
(Click for the stocks that their CEOs have bought)
2014-12-22Sell30,000699,370$9270-57.22699,370 (Direct)
STARR CHRISTOPHER MCEO2014-12-15Sell30,000699,370$8.15244.5-52.76699,370 (Direct)
STARR CHRISTOPHER MCEO2014-11-24Sell30,000699,370$9.97299.1-61.38699,370 (Direct)
STARR CHRISTOPHER MCEO2014-11-17Sell30,000699,370$9.91297.3-61.15699,370 (Direct)
SAGER ERICHDirector2014-11-12Sell46,96627,331$10.35486.1-62.827,331 (Direct)
STARR CHRISTOPHER MCEO2014-10-22Sell30,000699,370$10.25307.5-62.44699,370 (Direct)
STARR CHRISTOPHER MCEO2014-10-15Sell30,000699,370$10.04301.2-61.65699,370 (Direct)
STARR CHRISTOPHER MCEO2014-09-23Sell30,000699,370$10.21306.3-62.29699,370 (Direct)
STARR CHRISTOPHER MCEO2014-09-16Sell32,896699,370$10.6348.7-63.68699,370 (Direct)
Anderson RaymondDirector2014-09-10Sell10,0000$10.81108.1-64.38Link
SAGER ERICHDirector2014-08-25Sell10,00074,297$11.01110.1-65.0374,297 (Direct)
Anderson RaymondDirector2014-07-07Sell27,5000$11.21308.3-65.66Link
Keltner LlewDirector2014-07-07Sell10,0000$11.21112.1-65.66Link
Keltner LlewDirector2014-05-30Buy1000$8.370.8-54Link
Erbez GeorgiaCFO2014-05-13Buy16,10019,600$7.9127.2-51.2716,100 (Direct)
1,800 (Trustee for the benefit of Jake Phillip Erbez)
1,700 (Trustee for the benefit of Alexander D. Erbez)
SAMANT VIJAY BDirector2014-04-07Sell5,0000$8.5943-55.18Link
STARR CHRISTOPHER MCEO2014-03-17Sell19,316699,370$10.79208.4-64.32699,370 (Direct)
Walbert Timothy PDirector2014-03-13Sell5,5210$15.2284-74.7Link
Bruhn Suzanne LouiseDirector2014-03-13Sell2,7600$15.2142-74.69Link
Keltner LlewDirector2014-03-07Sell10,0000$15.73157.3-75.52Link
Anderson RaymondDirector2014-03-07Sell12,5000$15.72196.5-75.51Link
FRANKLIN RICHARD LDirector2014-03-03Sell10,7150$15.91170.5-75.8Link
STARR CHRISTOPHER MCEO2014-02-18Sell25,000699,370$15.26381.5-74.77699,370 (Direct)
SAGER ERICHDirector2014-02-18Sell10,00084,297$15.17151.7-74.6284,297 (Direct)
Bruhn Suzanne LouiseDirector2014-02-13Sell2,7600$14.9841.3-74.3Link
SAMANT VIJAY BDirector2014-02-07Sell5,0000$15.0475.2-74.4Link
STARR CHRISTOPHER MCEO2014-01-15Sell25,000699,370$15.42385.5-75.03699,370 (Direct)
Walbert Timothy PDirector2014-01-13Sell5,5200$15.0683.1-74.44Link
Bruhn Suzanne LouiseDirector2014-01-13Sell2,7600$15.0541.5-74.42Link
Daley Thomas EChief Business Officer2014-01-09Sell15,00039,906$14.17212.6-72.8339,906 (Direct)
Keltner LlewDirector2014-01-07Sell10,0000$13.25132.5-70.94Link
Anderson RaymondDirector2014-01-07Sell10,0000$13.25132.5-70.94Link
FRANKLIN RICHARD LDirector2014-01-02Sell10,7150$13.12140.6-70.66Link
Bruhn Suzanne LouiseDirector2013-12-16Sell2,7600$13.1936.4-70.81Link
STARR CHRISTOPHER MCEO2013-12-16Sell25,000699,370$13.36334-71.18699,370 (Direct)
SAMANT VIJAY BDirector2013-12-09Sell5,0000$13.8669.3-72.22Link
STARR CHRISTOPHER MCEO2013-11-15Sell25,000699,370$12.31307.8-68.72699,370 (Direct)
Walbert Timothy PDirector2013-11-13Sell5,5210$12.4468.7-69.05Link
Bruhn Suzanne LouiseDirector2013-11-13Sell2,7600$1335.9-70.38Link
Daley Thomas EChief Business Officer2013-11-11Sell15,00054,906$12.79191.9-69.954,906 (Direct)
Keltner LlewDirector2013-11-07Sell10,0000$14.05140.5-72.6Link
Anderson RaymondDirector2013-11-07Sell15,0000$14.04210.6-72.58Link
FRANKLIN RICHARD LDirector2013-11-04Sell10,7150$14.88159.4-74.13Link
STARR CHRISTOPHER MCEO2013-10-15Sell25,000699,370$13.77344.3-72.04699,370 (Direct)
Bruhn Suzanne LouiseDirector2013-10-14Sell2,7600$13.5837.5-71.65Link
SAMANT VIJAY BDirector2013-10-07Sell5,0000$14.7673.8-73.92Link
STARR CHRISTOPHER MCEO2013-09-16Sell25,000699,370$14.21355.3-72.91699,370 (Direct)
SAGER ERICHDirector2013-09-16Sell17,000130,727$14.21241.6-72.91130,727 (Direct)
Walbert Timothy PDirector2013-09-13Sell5,5200$14.0777.7-72.64Link
Bruhn Suzanne LouiseDirector2013-09-13Sell2,7600$14.0738.8-72.64Link
FRANKLIN RICHARD LDirector2013-09-09Sell10,7150$14.24152.6-72.96Link
Anderson RaymondDirector2013-09-09Sell15,0000$14.24213.6-72.96Link
Daley Thomas EPresident, Raptor Therapeutics2013-09-09Sell25,00069,906$14.28357-73.0469,906 (Direct)
Erbez GeorgiaCFO2013-08-30Sell7,4000$13.4299.3-71.31Link
Hyperion Trading Segregated Po10% Owner2013-08-23Sell279,3005,954,700$12.313438.2-68.725,954,700 (Direct)
Hyperion Trading Segregated Po10% Owner2013-08-13Sell616,5366,234,000$7.444587-48.256,234,000 (Direct)
Hyperion Trading Segregated Po10% Owner2013-04-05Sell243,9616,700,536$5.771407.7-33.286,700,536 (Direct)
STARR CHRISTOPHER MCEO2012-12-31Sell10,088699,370$5.6857.3-32.22699,370 (Direct)
Hyperion Trading Segregated Po10% Owner2012-12-31Buy1,266,1856,442,685$5.56964-306,442,685 (Direct)
Anderson RaymondDirector2012-12-28Sell2,0000$5.511-30Link
Daley Thomas EPresident, Raptor Therapeutics2012-12-17Sell3,33384,906$5.4518.2-29.3684,906 (Direct)
SAGER ERICHDirector2012-12-17Sell14,908108,074$5.4180.7-28.84108,074 (Direct)
SAGER ERICHDirector2012-11-27Sell3,629111,998$518.1-23111,998 (Direct)
SAGER ERICHDirector2012-11-26Sell11,279115,627$556.4-23115,627 (Direct)
Keltner LlewDirector2012-11-26Sell9690$54.8-23Link
Daley Thomas EPresident, Raptor Therapeutics2012-10-15Sell3,33388,239$5.2217.4-26.2588,239 (Direct)
Anderson RaymondDirector2012-10-01Sell2,0000$5.5811.2-31Link
STARR CHRISTOPHER MCEO2012-09-28Sell10,085699,370$5.3954.4-28.57699,370 (Direct)
SAGER ERICHDirector2012-09-17Sell14,908219,757$5.4180.7-28.84219,757 (Direct)
Keltner LlewDirector2012-09-17Sell9670$5.495.3-29.87Link
Anderson RaymondDirector2012-09-12Sell2,0000$5.511-30Link
Zankel ToddChief Scientific Officer2012-09-04Sell842651,866$54.2-23651,866 (Direct)
SAGER ERICHDirector2012-08-31Sell7,700223,681$538.5-23223,681 (Direct)
Zankel ToddChief Scientific Officer2012-08-31Sell10,148652,708$550.7-23652,708 (Direct)
SAGER ERICHDirector2012-08-29Sell3,284223,681$5.0116.5-23.15223,681 (Direct)
Zankel ToddChief Scientific Officer2012-08-29Sell10,136659,214$5.0150.8-23.15659,214 (Direct)
Tsuchimoto Kim RCFO2012-08-29Sell3,510582$517.6-23582 (Direct)
Zankel ToddChief Scientific Officer2012-08-27Sell287669,350$51.4-23669,350 (Direct)
Daley Thomas EPresident, Raptor Therapeutics2012-08-27Sell3,33391,572$516.7-2391,572 (Direct)
SAGER ERICHDirector2012-08-27Sell3,808223,681$519-23223,681 (Direct)
Tsuchimoto Kim RCFO2012-08-27Sell49582$50.2-23582 (Direct)
SAGER ERICHDirector2012-08-01Sell116227,489$50.6-23227,489 (Direct)
Keltner LlewDirector2012-08-01Sell9670$54.8-23Link
STARR CHRISTOPHER MCEO2012-06-29Sell10,085699,370$5.656.5-31.25699,370 (Direct)
Tsuchimoto Kim RCFO2012-06-15Sell3,559582$5.7720.5-33.28582 (Direct)
Daley Thomas EPresident, Raptor Therapeutics2012-06-15Sell3,33394,905$5.7719.2-33.2894,905 (Direct)
Hyperion Trading Segregated Po10% Owner2012-06-13Sell2,406,5002,503,787$5.4413091.4-29.232,503,787 (Direct)
Anderson RaymondDirector2012-06-08Sell1,9650$5.510.8-30Link
Anderson RaymondDirector2012-06-07Sell350$5.50.2-30Link
Keltner LlewDirector2012-05-15Sell9670$5.495.3-29.87Link
SAGER ERICHDirector2012-05-15Sell14,908227,605$5.5482.6-30.51227,605 (Direct)
Zankel ToddChief Scientific Officer2012-05-01Sell21,413669,350$5.84125.1-34.08669,350 (Direct)
Daley Thomas EPresident, Raptor Therapeutics2012-04-16Sell3,33398,238$6.0520.2-36.3698,238 (Direct)
Tsuchimoto Kim RCFO2012-04-16Sell3,559582$6.0521.5-36.36582 (Direct)
STARR CHRISTOPHER MCEO2012-04-02Sell10,0851,082,673$6.7267.8-42.711,082,673 (Direct)
Anderson RaymondDirector2012-04-02Sell6,128388,747$6.7241.2-42.71388,747 (Direct)
SAGER ERICHDirector2012-04-02Sell14,911507,512$6.73100.4-42.79507,512 (Direct)
SAGER ERICHDirector2012-04-02Sell14,911231,529$6.73100.4-42.79231,529 (Direct)
STARR CHRISTOPHER MCEO2012-04-02Sell10,085699,370$6.7267.8-42.71699,370 (Direct)
Anderson RaymondDirector2012-04-02Sell6,1280$6.7241.2-42.71Link
Keltner LlewDirector2012-03-15Sell9670$6.996.8-44.92Link
Anderson RaymondDirector2012-02-28Sell6,1280$7.2944.7-47.19Link
Daley Thomas EPresident, Raptor Therapeutics2012-02-15Sell3,333101,571$7.7425.8-50.26101,571 (Direct)
Tsuchimoto Kim RCFO2012-02-15Sell3,559582$7.7427.5-50.26582 (Direct)
Keltner LlewDirector2012-02-15Sell9670$7.747.5-50.26Link
Zankel ToddChief Scientific Officer2012-02-09Sell21,415686,834$7.73165.5-50.19686,834 (Direct)
ALTA PARTNERS2009-09-08Sell42,209538$0.229.32.9Link
Alta Partners III, Inc.2009-09-08Sell42,209538$0.229.32.9Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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