Switch to:

Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Clay B. Siegall,PhDPresident and CEO638,8350.45%2016-11-07
Todd E. SimpsonCFO209,4450.15%2016-08-27
Franklin M. BergerN/A204,7200.14%2014-02-21
Dr. Vaughn B. Himes,PhDEVP, Proc Svcs & Tech Ops135,3790.1%2016-08-31
Dr. Marc E. Lippman,M.D.Director131,350less than 0.1%2016-11-07
Jonathan G. DrachmanCMO & EVP, R & D109,837less than 0.1%2016-11-09
Dr. Felix J. Baker,PhDDirector, 10% Owner107,504less than 0.1%2016-11-07
Eric L. DobmeierCOO87,767less than 0.1%2016-09-14
Christopher S. BoernerN/A72,358less than 0.1%2014-08-24
Tim J. CarrollN/A62,861less than 0.1%2005-05-03

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
DRACHMAN JONATHAN GCMO & EVP, R & D2016-11-09Sell7,751109,837$66.75517.38-0.07109,837 (Direct)
BAKER FELIXDirector, 10% Owner2016-11-08Buy382,50040,992,596$59.3622705.212.37107,504 (Direct)
40,885,092 (See footnote(,,,))
SIEGALL CLAY BPresident and CEO
(Click for the stocks that their CEOs have bought)
2016-11-07Sell14,465638,835$58.43845.1914.15638,835 (Direct)
LIPPMAN MARC EDirector2016-11-07Sell1,000131,350$57.7557.7515.5131,350 (Direct)
BAKER FELIXDirector, 10% Owner2016-11-03Buy198,43345,482,921$56.4311197.5718.2107,504 (Direct)
4,835,170 (See footnote(,,,))
40,540,247 (See Footnote(,,,))
BAKER FELIXDirector, 10% Owner2016-11-03Buy1,030,62945,194,447$56.1357849.2118.83107,504 (Direct)
4,725,543 (See footnote(,,,))
40,361,400 (See Footnote(,,,))
DRACHMAN JONATHAN GCMO & EVP, R & D2016-11-01Sell3,418109,837$51.74176.8528.91109,837 (Direct)
SIEGALL CLAY BPresident and CEO2016-10-06Sell14,465638,835$54.41787.0422.59638,835 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2016-09-22Sell2,249113,255$56.75127.6317.53113,255 (Direct)
DOBMEIER ERICCOO2016-09-14Sell22,91887,767$54.041238.4923.4387,767 (Direct)
BAKER FELIXDirector, 10% Owner2016-09-13Buy447,31144,233,991$50.7122683.1431.53107,504 (Direct)
4,693,991 (See footnote(,,,))
39,432,496 (See Footnote(,,,))
SIEGALL CLAY BPresident and CEO2016-09-08Sell31,269638,835$50.081565.9533.19638,835 (Direct)
0 (by Trust)
BAKER FELIXDirector, 10% Owner2016-09-08Buy414,01643,696,884$48.4320050.7937.72107,504 (Direct)
4,559,012 (See footnote(,,,))
39,030,368 (See Footnote(,,,))
SIEGALL CLAY BPresident and CEO2016-09-06Sell11,653644,983$45.4529.0546.92617,038 (Direct)
27,945 (by Trust)
Cline Darren SEVP, Commercial2016-09-06Sell5,39751,576$46.01248.3244.9751,576 (Direct)
DOBMEIER ERICCOO2016-08-23Sell12,58958,767$48604.2738.9658,767 (Direct)
Cline Darren SEVP, Commercial2016-08-22Sell1,77440,973$46.5982.6543.1640,973 (Direct)
DOBMEIER ERICCOO2016-08-22Sell5,41167,525$46.59252.143.1667,525 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2016-08-22Sell3,99184,255$46.59185.9443.1684,255 (Direct)
HIMES VAUGHN BEVP, Proc Svcs & Tech Ops2016-08-22Sell3,991108,779$46.59185.9443.16108,779 (Direct)
SIEGALL CLAY BPresident and CEO2016-08-22Sell23,381560,679$46.591089.3243.16532,734 (Direct)
27,945 (by Trust)
SIMPSON TODD ECFO2016-08-22Sell3,991191,445$46.59185.9443.16191,445 (Direct)
SIEGALL CLAY BPresident and CEO2016-08-08Sell11,660584,060$47.19550.2441.34556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-07-27Sell4,042584,060$45.2182.747.57556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-07-06Sell7,618584,060$40.56308.9964.45556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-06-06Sell22,083584,060$43.59962.653.02556,115 (Direct)
27,945 (by Trust)
Cline Darren SEVP, Commercial2016-06-02Sell3,36642,747$42.07141.6158.5542,747 (Direct)
SIEGALL CLAY BPresident and CEO2016-05-27Sell48,660584,060$40.411966.3565.06556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-05-24Sell8,400584,060$40.09336.7666.38556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-05-17Sell7,618584,060$35.16267.8589.7556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-04-25Sell800584,060$403266.75556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-04-05Sell7,618584,060$36.12275.1684.66556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-03-22Sell15,236584,060$35.52541.1887.78556,115 (Direct)
27,945 (by Trust)
BAKER FELIXDirector, 10% Owner2016-03-17Buy124,06547,873,417$31.853951.47109.42107,504 (Direct)
4,486,246 (See footnotes(F4,F5,F8,F9))
38,783,387 (See footnotes(F5,F6,F8,F9))
4,496,280 (See Footnotes(F4,F5,F8,F9))
BAKER FELIXDirector, 10% Owner2016-03-16Buy1,349,23747,668,558$32.143310.51107.79107,504 (Direct)
4,484,096 (See footnotes(F4,F5,F14,F15))
38,671,506 (See footnotes(F5,F6,F14,F15))
4,405,452 (See Footnotes(F4,F5,F14,F15))
BAKER FELIXDirector, 10% Owner2016-03-11Buy694,66646,212,264$32.4622548.86105.48107,504 (Direct)
4,351,589 (See footnotes(F4,F5,F14,F15))
37,454,776 (See footnotes(F5,F6,F14,F15))
4,298,395 (See Footnotes(F4,F5,F14,F15))
BAKER FELIXDirector, 10% Owner2016-03-08Buy502,523127,365,973$22.6611387.17194.35107,504 (Direct)
4,255,959 (See footnotes(F4,F17))
36,682,540 (See footnotes(F5,F17))
4,249,772 (See Footnotes(F4,F17))
4,265,959 (See footnotes(F9,F12,F13,F17))
36,692,540 (See footnotes(F10,F12,F14,F17))
4,281,431 (See footnotes(F13,F17))
36,830,268 (See footnotes(F14,F17))
BAKER FELIXDirector, 10% Owner2016-03-02Buy675,92244,876,220$31.7721474.04109.95107,504 (Direct)
4,221,368 (See footnotes(F4,F9))
36,367,808 (See footnotes(F5,F9))
4,179,540 (See Footnotes(F4,F9))
BAKER FELIXDirector, 10% Owner2016-02-26Buy314,50844,148,952$29.559293.71125.72107,504 (Direct)
4,154,719 (See footnotes(F4,F9))
35,758,535 (See footnotes(F5,F9))
4,128,194 (See Footnotes(F4,F9))
BAKER FELIXDirector, 10% Owner2016-02-22Buy1,001,47143,804,485$29.6329673.59125.11107,504 (Direct)
4,122,878 (See footnotes(F4,F7))
35,475,868 (See footnotes(F5,F7))
4,098,235 (See Footnotes(F4,F7))
BAKER FELIXDirector, 10% Owner2016-02-17Buy1,269,14776,210,189$30.4338620.14119.19107,504 (Direct)
3,916,805 (See footnotes(F4,F11))
33,588,605 (See footnotes(F5,F11))
4,023,889 (See Footnotes(F4,F11))
34,573,386 (See Footnotes(F5,F11))
Orwin John ADirector2016-02-12Buy2,00010,700$28.3356.66135.4410,700 (Direct)
HIMES VAUGHN BEVP, Proc Svcs & Tech Ops2015-12-15Sell40,50076,212$39.941617.576776,212 (Direct)
SIEGALL CLAY BPresident and CEO2015-12-03Sell3,720584,060$39.99148.7666.79556,115 (Direct)
27,945 (by Trust)
BAKER FELIXDirector, 10% Owner2015-11-20Buy329,35837,435,632$43.9414471.9951.8107,504 (Direct)
3,899,276 (See footnote)
33,428,852 (See Footnote)
SIEGALL CLAY BPresident and CEO2015-11-17Sell87,473584,060$45.43971.2746.92556,115 (Direct)
27,945 (by Trust)
Cline Darren SSVP, Commercial2015-11-11Sell5,76937,713$45.68263.5346.0237,713 (Direct)
BAKER FELIXDirector, 10% Owner2015-11-10Buy934,6244,006,780$42.9540142.155.3107,504 (Direct)
3,899,276 (See footnote)
DOBMEIER ERICCOO2015-11-06Sell17,45280,888$42.5741.7156.9480,888 (Direct)
GRYSKA DAVID WDirector2015-11-05Sell10,00023,950$43.57435.753.0923,950 (Direct)
SIEGALL CLAY BPresident and CEO2015-11-04Sell3,718671,533$43.14160.3954.61643,588 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2015-10-05Sell3,718639,268$41.3153.5561.5611,323 (Direct)
27,945 (by Trust)
BAKER FELIXDirector, 10% Owner2015-09-15Buy5,159,4844,006,780$42.56219587.6456.72107,504 (Direct)
3,899,276 (See footnote)
SIEGALL CLAY BPresident and CEO2015-09-03Sell3,718639,268$40.12149.1766.25611,323 (Direct)
27,945 (by Trust)
DOBMEIER ERICCOO2015-08-20Sell8,54898,340$42.02359.1958.7398,340 (Direct)
Cline Darren SSVP, Commercial2015-08-20Sell2,23143,482$42.0293.7558.7343,482 (Direct)
SIEGALL CLAY BPresident and CEO2015-08-20Sell31,754639,268$42.021334.358.73611,323 (Direct)
27,945 (by Trust)
DOBMEIER ERICCOO2015-08-20Sell8,54898,340$42.02359.1958.7398,340 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2015-08-20Sell4,46282,724$42.02187.4958.7382,724 (Direct)
Cline Darren SSVP, Commercial2015-08-20Sell2,23143,482$42.0293.7558.7343,482 (Direct)
SIMPSON TODD ECFO2015-08-20Sell5,825179,874$42.02244.7758.73179,874 (Direct)
HIMES VAUGHN BEVP, Proc Svcs & Tech Ops2015-08-20Sell5,99776,212$42.02251.9958.7376,212 (Direct)
SIEGALL CLAY BPresident and CEO2015-08-05Sell3,718657,022$46.91174.4142.19557,022 (Direct)
100,000 (by Trust)
SIEGALL CLAY BPresident and CEO2015-07-06Sell3,718657,022$46.94174.5242.1557,022 (Direct)
100,000 (by Trust)
SIEGALL CLAY BPresident and CEO2015-06-03Sell3,718657,022$45.72169.9945.89557,022 (Direct)
100,000 (by Trust)
BAKER FELIXDirector, 10% Owner2015-05-21Buy950,8864,006,780$42.4940403.1556.98107,504 (Direct)
3,899,276 (See footnote)
SIEGALL CLAY BPresident and CEO2015-05-08Sell52,052657,022$40.652115.9164.08557,022 (Direct)
100,000 (by Trust)
DOBMEIER ERICCOO2015-05-08Sell17,07482,777$40.38689.4565.1882,777 (Direct)
BAKER FELIXDirector, 10% Owner2015-05-07Buy1,032,6643,993,080$35.5636721.5387.57107,504 (Direct)
3,885,576 (See footnote)
Cline Darren SSVP, Commercial2015-03-13Sell7,50033,135$38.65289.8872.5733,135 (Direct)
HIMES VAUGHN BEVP, Proc Svcs & Tech Ops2015-03-12Sell20,00067,209$36.6573381.9967,209 (Direct)
BAKER FELIXDirector, 10% Owner2015-03-10Buy285,0363,993,080$34.669879.3592.44107,504 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2015-03-04Buy448,8413,993,080$34.8415637.6291.45107,504 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2015-02-25Buy281,1153,993,080$33.929535.4296.64107,504 (Direct)
3,885,576 (See footnote)
SIEGALL CLAY BPresident and CEO2015-01-06Sell16,804659,710$31.8534.37109.75559,710 (Direct)
100,000 (by Trust)
BAKER FELIXDirector, 10% Owner2014-12-16Buy2,883,3783,993,080$31.8691864.42109.35107,504 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2014-12-10Buy1,247,8963,993,080$33.8242203.8497.22107,504 (Direct)
3,885,576 (See footnote)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2014-11-12Sell10,00067,209$37.52375.277.7767,209 (Direct)
BAKER FELIXDirector, 10% Owner2014-11-10Buy1,653,925493,205$34.5657159.659376,997 (Direct)
416,208 (See footnote)
SIEGALL CLAY BPresident and CEO2014-09-04Sell5,600659,710$42.54238.2256.79559,710 (Direct)
100,000 (by Trust)
DOBMEIER ERICCOO2014-08-25Sell4,81891,432$43.55209.8253.1691,432 (Direct)
SIMPSON TODD ECFO2014-08-24Sell3,696168,699$43.55160.9653.16168,699 (Direct)
SIEGALL CLAY BPresident and CEO2014-08-24Sell25,507659,710$43.551110.8353.16559,710 (Direct)
100,000 (by Trust)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2014-08-24Sell3,31067,209$43.55144.1553.1667,209 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2014-08-24Sell2,77266,481$43.55120.7253.1666,481 (Direct)
BOERNER CHRISTOPHER S.Executive Vice President, Comm2014-08-24Sell1,24872,358$43.5554.3553.1672,358 (Direct)
SIEGALL CLAY BPresident and CEO2014-08-12Sell11,200625,217$40.38452.2665.18525,217 (Direct)
100,000 (by Trust)
BAKER FELIXDirector, 10% Owner2014-06-13Buy216,5953,962,573$39.928646.4767.0876,997 (Direct)
3,885,576 (See footnote)
SIEGALL CLAY BPresident and CEO2014-06-10Sell11,200625,217$40.14449.5766.17525,217 (Direct)
100,000 (by Trust)
BAKER FELIXDirector, 10% Owner2014-06-09Buy546,2523,962,573$38.1620844.9874.7976,997 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2014-06-04Buy281,9633,962,573$34.869829.2391.3476,997 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2014-05-16Buy189,611467,941$34.076460.0595.7776,997 (Direct)
390,944 (See footnote)
BAKER FELIXDirector, 10% Owner2014-05-09Buy488,3823,949,073$33.9616585.4596.4176,997 (Direct)
3,872,076 (See footnote)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2014-05-09Sell10,00055,519$3535090.5755,519 (Direct)
SIEGALL CLAY BPresident and CEO2014-04-03Sell5,600955,696$43.34242.753.9955,696 (Direct)
SIEGALL CLAY BPresident and CEO2014-03-05Sell9,318955,696$52.89492.8326.11955,696 (Direct)
BOERNER CHRISTOPHER S.SVP, Commercial2014-02-21Sell1,45246,075$54.9879.8321.3246,075 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2014-02-20Sell1,24148,670$53.2566.0825.2648,670 (Direct)
HIMES VAUGHN BEVP, Tech, Ops. & Proc. Sci.2014-02-19Sell5,08844,219$52.01264.6328.2444,219 (Direct)
SIEGALL CLAY BPresident and CEO2014-02-18Sell100,000955,696$51.97519728.34955,696 (Direct)
DOBMEIER ERICCOO2014-01-21Sell56,01077,833$47.92268439.1977,833 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2014-01-16Sell1,20149,911$45.7554.9545.7949,911 (Direct)
SIEGALL CLAY BPresident and CEO2014-01-02Sell1,8581,043,554$39.2772.9669.851,043,554 (Direct)
BAKER FELIXDirector, 10% Owner2013-12-16Buy407,0783,949,073$39.6616144.7168.1876,997 (Direct)
3,872,076 (See footnote)
BAKER FELIXDirector, 10% Owner2013-12-05Buy1,005,9013,949,073$43.1943444.8654.4376,997 (Direct)
3,872,076 (See footnote)
SIEGALL CLAY BPresident and CEO2013-12-02Sell2,0001,024,558$41.2582.561.71,024,558 (Direct)
SIEGALL CLAY BPresident and CEO2013-11-01Sell2,0001,024,558$38.6377.2672.661,024,558 (Direct)
SIEGALL CLAY BPresident and CEO2013-10-01Sell2,0001,024,558$43.8787.7452.041,024,558 (Direct)
DOBMEIER ERICCOO2013-09-10Sell42,000133,843$46.41948.843.75133,843 (Direct)
DOBMEIER ERICCOO2013-09-05Sell75,000135,843$42.64319856.43135,843 (Direct)
SIEGALL CLAY BPresident and CEO2013-09-03Sell102,000977,211$43.94477.851.94977,211 (Direct)
GRYSKA DAVID WDirector2013-09-03Sell10,00022,000$42.48424.857.0222,000 (Direct)
SIMPSON TODD ECFO2013-08-27Sell37,763155,395$41.451565.2860.92155,395 (Direct)
SIEGALL CLAY BPresident and CEO2013-08-19Sell7,6531,124,558$40.91313.0863.041,124,558 (Direct)
SIMPSON TODD ECFO2013-08-19Sell3,328125,029$40.91136.1563.04125,029 (Direct)
DOBMEIER ERICCOO2013-08-19Sell3,328127,620$40.91136.1563.04127,620 (Direct)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2013-08-19Sell1,73646,307$40.9171.0263.0446,307 (Direct)
BOERNER CHRISTOPHER S.SVP, Commercial2013-08-19Sell22647,527$40.919.2563.0447,527 (Direct)
SIEGALL CLAY BPresident and CEO2013-08-01Sell2,0001,077,211$40.0380.0666.631,077,211 (Direct)
SIMPSON TODD ECFO2013-07-12Sell92,527113,957$37.453465.1478.1113,957 (Direct)
SIEGALL CLAY BPresident and CEO2013-07-01Sell2,0001,077,211$32.5965.18104.661,077,211 (Direct)
AKKARAJU SRINIVASDirector2013-06-14Sell5,00013,905$32.75163.75103.6613,905 (Direct)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2013-06-13Sell10,00033,643$32.11321.1107.7233,643 (Direct)
SIEGALL CLAY BPresident and CEO2013-06-03Sell2,0001,077,211$33.8867.7696.871,077,211 (Direct)
AKKARAJU SRINIVASDirector2013-05-10Sell17,50010,405$37.17650.4879.4510,405 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-09Buy488,3823,949,073$33.9616585.4596.4176,997 (Direct)
3,872,076 (See footnote)
SIEGALL CLAY BPresident and CEO2013-05-01Sell2,0001,077,211$36.5873.1682.341,077,211 (Direct)
SIEGALL CLAY BPresident and CEO2013-04-01Sell2,0001,077,211$35.5371.0687.731,077,211 (Direct)
BOERNER CHRISTOPHER S.SVP, Commercial2013-03-15Sell8,50033,753$33.61285.6998.4533,753 (Direct)
DOBMEIER ERICCOO2013-03-11Sell60,000112,948$31.161869.6114.06112,948 (Direct)
SIMPSON TODD ECFO2013-03-07Sell49,718113,957$30.751528.83116.91113,957 (Direct)
DOBMEIER ERICCOO2013-03-06Sell100,000122,948$29.682968124.73122,948 (Direct)
SIEGALL CLAY BPresident and CEO2013-03-05Sell95,7501,077,211$28.712748.98132.321,077,211 (Direct)
GRYSKA DAVID WDirector2013-02-25Sell10,00018,500$27.17271.7145.4918,500 (Direct)
SIEGALL CLAY BPresident and CEO2013-02-01Sell2,0001,170,961$29.6159.22125.261,170,961 (Direct)
Reynolds Thomas CChief Medical Officer2013-01-28Sell7,29057,601$30.09219.36121.6757,601 (Direct)
Reynolds Thomas CChief Medical Officer2013-01-15Sell125,07957,601$283502.21138.2157,601 (Direct)
SIEGALL CLAY BPresident and CEO2013-01-04Sell8,2491,170,961$24.13199.05176.421,170,961 (Direct)
DOBMEIER ERICCOO2013-01-04Sell50,983122,846$24.951272.03167.33122,846 (Direct)
DOBMEIER ERICCOO2012-12-17Sell50,000113,829$23.71185181.43113,829 (Direct)
Reynolds Thomas CChief Medical Officer2012-12-10Sell66,58857,601$25.771715.97158.8357,601 (Direct)
Reynolds Thomas CChief Medical Officer2012-12-05Sell40,00057,601$25.591023.6160.6557,601 (Direct)
SIEGALL CLAY BPresident and CEO2012-12-03Sell8,2501,170,961$25.19207.82164.791,170,961 (Direct)
Reynolds Thomas CChief Medical Officer2012-12-03Sell40,00057,601$25.411016.4162.557,601 (Direct)
Reynolds Thomas CChief Medical Officer2012-11-26Sell30,00057,601$25.34760.2163.2257,601 (Direct)
Reynolds Thomas CChief Medical Officer2012-11-20Sell20,00057,601$24.95499167.3357,601 (Direct)
DOBMEIER ERICCOO2012-11-13Sell27,327101,411$23.59644.64182.75101,411 (Direct)
SIEGALL CLAY BPresident and CEO2012-11-01Sell8,2501,170,961$25.51210.46161.471,170,961 (Direct)
DOBMEIER ERICCOO2012-10-15Sell25,00069,352$25.01625.25166.6969,352 (Direct)
SIEGALL CLAY BPresident and CEO2012-10-01Sell8,2501,170,961$26.59219.37150.851,170,961 (Direct)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2012-09-10Sell10,00033,643$28.79287.9131.6833,643 (Direct)
SIMPSON TODD ECFO2012-09-06Sell95,00070,762$28.52707.5134.0470,762 (Direct)
Reynolds Thomas CChief Medical Officer2012-09-06Sell48,54057,601$29.751444.07124.257,601 (Direct)
SIEGALL CLAY BPresident and CEO2012-09-04Sell8,2501,170,961$26.54218.96151.321,170,961 (Direct)
SIMPSON TODD ECFO2012-08-27Sell45,00070,762$26.971213.65147.3170,762 (Direct)
SIMPSON TODD ECFO2012-08-16Sell40,00050,762$25.971038.8156.8350,762 (Direct)
DOBMEIER ERICCOO2012-08-13Sell25,00043,352$24.01600.25177.843,352 (Direct)
SIEGALL CLAY BPresident and CEO2012-08-02Sell8,2501,096,711$26214.5156.541,096,711 (Direct)
SIEGALL CLAY BPresident & CEO2012-07-02Sell8,2501,096,711$25.36209.22163.011,096,711 (Direct)
DOBMEIER ERICCOO2012-06-18Sell25,00068,073$25.36634163.0168,073 (Direct)
SIMPSON TODD ECFO2012-06-14Sell95,00050,762$24.52327.5172.2450,762 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-06-12Sell10,00017,643$24240177.9217,643 (Direct)
SIMPSON TODD ECFO2012-06-08Sell35,00050,762$22.97803.95190.3850,762 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-06-07Sell13,56617,643$22.5305.24196.4417,643 (Direct)
GRYSKA DAVID WDirector2012-06-05Sell8,00011,500$19.75158237.7211,500 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-05-18Sell65,00017,643$21.541400.1209.6617,643 (Direct)
Reynolds Thomas CChief Medical Officer2012-05-15Sell94931,073$19.7518.74237.7231,073 (Direct)
Reynolds Thomas CChief Medical Officer2012-04-25Sell40,00031,073$19.75790237.7231,073 (Direct)
DOBMEIER ERICCOO2012-04-25Sell25,00068,073$19.95498.75234.3468,073 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-04-20Sell38,28117,643$19.51746.86241.8817,643 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-04-17Sell44,21917,643$18.88834.85253.2817,643 (Direct)
Reynolds Thomas CChief Medical Officer2012-03-22Sell40,00031,073$19.78791.2237.2131,073 (Direct)
Reynolds Thomas CChief Medical Officer2012-03-19Sell40,00031,073$19.75790237.7231,073 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-03-13Sell69,62617,643$18.591294.35258.817,643 (Direct)
DOBMEIER ERICCOO2012-02-28Sell46,00072,073$18.52851.92260.1572,073 (Direct)
DOBMEIER ERICCOO2012-02-28Sell4,00068,073$18.5374.12259.9668,073 (Direct)
Reynolds Thomas CChief Medical Officer2012-01-27Sell40,00030,169$19.75790237.7230,169 (Direct)
SIEGALL CLAY BPresident and CEO2012-01-03Sell15,0001,130,055$16.73250.95298.681,045,055 (Direct)
85,000 (by Trust)
GRYSKA DAVID WDirector2011-12-09Sell10,00015,000$18.09180.9268.7115,000 (Direct)
SIEGALL CLAY BPresident and CEO2011-12-01Sell15,0001,130,055$15.97239.55317.661,045,055 (Direct)
85,000 (by Trust)
SIEGALL CLAY BPresident and CEO2011-11-01Sell15,0001,130,055$21.89328.35204.711,045,055 (Direct)
85,000 (by Trust)
DOBMEIER ERICCOO2011-10-27Sell20,91859,327$21.95459.15203.8759,327 (Direct)
DOBMEIER ERICCOO2011-10-20Sell20,46159,327$20.58421.09224.159,327 (Direct)
SIMPSON TODD ECFO2011-10-07Sell24,35049,242$21.97534.97203.649,242 (Direct)
SIEGALL CLAY BPresident and CEO2011-10-04Sell15,0001,130,055$20.15302.25231.021,045,055 (Direct)
85,000 (by Trust)
SIEGALL CLAY BPresident and CEO2011-09-21Sell30,0001,130,055$20.12603.6231.511,045,055 (Direct)
85,000 (by Trust)
14159 capital (GP), LLCDirector, 10% Owner2011-09-06Buy1,773323,148$17.0830.28290.52
323,148 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-09-06Buy129,18714,776,080$17.082206.51290.52
14,776,080 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-08-25Buy1,165,43514,646,893$15.3817924.39333.68
14,646,893 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-08-25Buy17,926321,375$15.38275.7333.68
321,375 (Through Partnership)
Reynolds Thomas CChief Medical Officer2011-08-01Sell1,5391,488$17.3726.732841,488 (Direct)
SIEGALL CLAY BPresident and CEO2011-07-01Sell15,0001,035,667$20.66309.9222.85950,667 (Direct)
85,000 (by Trust)
BERGER FRANKLIN MDirector2011-06-22Buy7,000163,720$20.04140.28232.83163,720 (Direct)
SIEGALL CLAY BPresident and CEO2011-06-20Sell9,0001,035,667$20.01180.09233.33950,667 (Direct)
85,000 (by Trust)
DOBMEIER ERICCOO2011-06-20Sell13,3858,817$20267.7233.58,817 (Direct)
SIEGALL CLAY BPresident and CEO2011-06-09Sell1,0001,035,667$2020233.5950,667 (Direct)
85,000 (by Trust)
DOBMEIER ERICChief Business Officer2011-06-09Sell3,60022,202$2072233.522,202 (Direct)
SIMPSON TODD ECFO2011-06-07Sell10,7509,359$19.96214.57234.179,359 (Direct)
ROSENBERG MORRISEVP, Process Sciences2011-06-07Sell2,5030$19.6749.23239.1Link
ROSENBERG MORRISEVP, Process Sciences2011-05-27Sell17,4970$19.5341.19242.05Link
Reynolds Thomas CChief Medical Officer2011-05-19Sell19,9983,027$18.71374.16256.493,027 (Direct)
ROSENBERG MORRISEVP, Process Sciences2011-05-19Sell20,0000$18.8376254.79Link
SIMPSON TODD ECFO2011-05-18Sell21,2509,359$18.64396.1257.839,359 (Direct)
ROSENBERG MORRISEVP, Process Sciences2011-05-13Sell20,0000$17.8356274.72Link
Reynolds Thomas CChief Medical Officer2011-05-13Sell20,0003,027$17.8356274.723,027 (Direct)
DOBMEIER ERICChief Business Officer2011-05-13Sell42,71525,802$18768.87270.5625,802 (Direct)
SIEGALL CLAY BPresident and CEO2011-05-09Sell50,0001,030,667$17.35867.5284.44945,667 (Direct)
85,000 (by Trust)
SIMPSON TODD ECFO2011-05-09Sell20,0009,359$17.74354.8275.999,359 (Direct)
SIEGALL CLAY BPresident and CEO2011-05-02Sell50,0000$17.43871.5282.67Link
ROSENBERG MORRISEVP, Process Sciences2011-05-02Sell25,0000$17.15428.75288.92Link
SIMPSON TODD ECFO2011-04-29Sell15,0000$16.94254.1293.74Link
Reynolds Thomas CChief Medical Officer2011-04-29Sell11,9150$16.95201.96293.51Link
SIEGALL CLAY BPresident and CEO2011-04-14Sell50,0000$15.27763.5336.8Link
SIEGALL CLAY BPresident and CEO2011-04-07Sell50,0000$16.06803315.32Link
DOBMEIER ERICChief Business Officer2011-04-05Sell40,0000$16640316.88Link
SIEGALL CLAY BPresident and CEO2011-03-17Sell200,0000$14.092818373.39Link
14159 capital (GP), LLCDirector, 10% Owner2011-02-02Buy48,1970$15.5747.05330.32Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-02-02Buy1,751,80313,470,692$15.527152.95330.32
13,470,692 (Through Partnership)
ROSENBERG MORRISEVP, Process Sciences2010-12-15Sell25,0000$16.22405.5311.22Link
ROSENBERG MORRISEVP, Process Sciences2010-12-02Sell25,0000$15.81395.25321.88Link
ROSENBERG MORRISEVP, Process Sciences2010-11-04Sell25,0000$14.7367.5353.74Link
Reynolds Thomas CChief Medical Officer2010-10-11Sell25,0005,719$16.95423.75293.51Link
Reynolds Thomas CChief Medical Officer2010-09-27Sell25,0005,719$14.95373.75346.15Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-06-08Buy599,06911,718,889$11.947152.88458.63Link
14159 capital (GP), LLCDirector, 10% Owner2010-06-08Buy16,536255,252$11.94197.44458.63Link
LIPPMAN MARC EDirector2010-06-04Buy20,000103,575$12.49249.8434.03Link
14159 capital (GP), LLCDirector, 10% Owner2010-05-25Buy150238,716$11.951.79458.16Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-05-25Buy5,41611,119,820$11.9564.72458.16Link
BERGER FRANKLIN MDirector2010-05-13Buy5,000138,720$13.3766.85398.88Link
LIPPMAN MARC EDirector2010-05-10Buy11,07583,575$11.92132.01459.56Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-05-04Buy561,70911,114,404$12.797184.26421.5Link
14159 capital (GP), LLCDirector, 10% Owner2010-05-04Buy15,506238,566$12.79198.32421.5Link
Reynolds Thomas CChief Medical Officer2010-05-03Sell25,0004,508$12.95323.75415.06Link
14159 capital (GP), LLCDirector, 10% Owner2010-04-30Buy51,581223,060$11.06570.49503.07Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-04-30Buy1,868,68610,552,695$11.0620667.67503.07Link
BERGER FRANKLIN MDirector2010-03-30Buy11,500116,720$12.05138.58453.53Link
BERGER FRANKLIN MDirector2010-03-12Buy13,000105,220$11.9154.7460.5Link
AKKARAJU SRINIVASDirector2009-08-18Buy4,90510,405$11.4756.26481.52Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-11Buy273,4044,626,213$10.752939.09520.47Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-11Buy798481,890$10.758.58520.47Link
Reynolds Thomas CChief Medical Officer2009-07-30Sell25,0003,713$12.47311.75434.88Link
DOBMEIER ERICChief Business Officer2009-07-30Sell60,00012,206$12.36741.6439.64Link
ROSENBERG MORRISEVP, Development2009-07-28Sell25,0000$11.81295.25464.78Link
AKKARAJU SRINIVASDirector2009-06-25Buy5,5005,500$9.2150.66624.21
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-05-20Buy378,0534,352,809$9.723674.68586.21
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-20Buy746,5718,684,009$9.727256.67586.21
14159 capital (GP), LLCDirector, 10% Owner2009-05-20Buy14,576171,479$9.72141.68586.21
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-20Buy3,710481,092$9.7236.06586.21
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-20Buy35,253400,898$9.72342.66586.21
DOBMEIER ERICChief Business Officer2008-09-26Sell24,4279,000$11.53281.64478.49
AKKARAJU SRINIVASDirector2008-09-22Sell18,601600,559$12.79237.91421.5
Reynolds Thomas CChief Medical Officer2008-09-22Sell12,3092,626$12.52154.11432.75
AKKARAJU SRINIVASDirector2008-09-19Sell37,011603,588$12.74471.52423.55
AKKARAJU SRINIVASDirector2008-09-19Sell87,696603,588$12.741117.25423.55
AKKARAJU SRINIVASDirector2008-09-18Sell20,839617,871$12.71264.86424.78
AKKARAJU SRINIVASDirector2008-09-18Sell49,378617,871$12.71627.59424.78
DOBMEIER ERICChief Business Officer2008-09-16Sell30,00033,427$12.25367.5444.49
ROSENBERG MORRISSr. VP, Development2008-08-04Sell50,0000$11.3565490.27
AKKARAJU SRINIVASDirector2008-07-29Sell95,688625,913$10.851038.21514.75
AKKARAJU SRINIVASDirector2008-07-28Sell21,232685,702$10.36219.96543.82
H&Q Holdings, Inc.10% Owner2008-07-28Sell21,50025,052$10.36222.74543.82
SIEGALL CLAY BPresident and CEO, Director2008-07-25Sell100,000953,168$10.781078518.74
H&Q Holdings, Inc.10% Owner2008-07-25Sell150,00025,186$10.811621.5517.02
JP MORGAN PARTNERS BHCA LP10% Owner2008-07-25Sell150,00025,186$10.811621.5517.02
AKKARAJU SRINIVASDirector2008-07-25Sell148,136701,432$10.811601.35517.02
JP MORGAN PARTNERS BHCA LP10% Owner2008-07-25Sell21,50025,052$10.36222.74543.82
AKKARAJU SRINIVASDirector2008-05-16Sell42,059811,175$10.39436.99541.96
AKKARAJU SRINIVASDirector2008-05-15Sell98,758842,334$10.141001.41557.79
JP MORGAN PARTNERS BHCA LP10% Owner2008-05-15Sell100,00026,383$10.141014557.79
H&Q Holdings, Inc.10% Owner2008-05-14Sell122,89327,004$10.11241.22560.4
JP MORGAN PARTNERS BHCA LP10% Owner2008-05-14Sell122,89327,004$10.11241.22560.4
AKKARAJU SRINIVASDirector2008-05-14Sell121,365915,496$10.11225.79560.4
H&Q Holdings, Inc.10% Owner2008-05-13Sell51,53627,768$10.06518.45563.02
JP MORGAN PARTNERS BHCA LP10% Owner2008-05-13Sell51,53627,768$10.06518.45563.02
AKKARAJU SRINIVASDirector2008-05-13Sell50,8961,005,407$10.06512.01563.02
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-03-18Buy41,6663,974,756$7.9329.16744.3
14159 capital (GP), LLCDirector, 10% Owner2008-03-18Buy3,918156,903$7.930.95744.3
Baker Brothers Life Sciences CDirector, 10% Owner2008-03-18Buy123,4937,937,438$7.9975.59744.3
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-03-17Buy189477,241$7.81.47755.13
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-03-14Buy65,0043,933,090$8.04522.63729.6
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-03-14Buy361477,052$8.072.91726.52
Baker / Tisch Capital (GP), LLDirector, 10% Owner2008-03-14Buy819365,645$8.046.58729.6
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-03-14Buy361477,052$8.072.91726.52
Baker Brothers Life Sciences CDirector, 10% Owner2008-03-14Buy173,4077,813,945$8.041394.19729.6
14159 capital (GP), LLCDirector, 10% Owner2008-03-14Buy5,503152,985$8.0444.24729.6
Baker / Tisch Capital (GP), LLDirector, 10% Owner2008-02-11Buy1,158364,826$9.0310.46638.65
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-02-11Buy177476,588$9.031.6638.65
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-02-11Buy34,6533,868,086$9.01312.22640.29
Baker Brothers Life Sciences CDirector, 10% Owner2008-02-11Buy153,5387,640,538$9.011383.38640.29
14159 capital (GP), LLCDirector, 10% Owner2008-02-11Buy4,883147,482$9.0144640.29
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-01-23Buy5,006476,173$945.05641.11
Baker / Tisch Capital (GP), LLDirector, 10% Owner2008-01-23Buy43,170363,668$8.99388.1641.94
Baker Brothers Life Sciences CDirector, 10% Owner2008-01-23Buy2,094,2787,487,000$8.9918827.56641.94
14159 capital (GP), LLCDirector, 10% Owner2008-01-23Buy67,001142,599$8.99602.34641.94
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-01-22Buy578,9163,833,433$8.995204.45641.94
BERGER FRANKLIN MDirector2008-01-22Buy52872,220$9.124.82631.36
JP MORGAN PARTNERS BHCA LP10% Owner2007-12-10Sell21,22428,088$12.63268.06428.11
AKKARAJU SRINIVASDirector2007-12-10Sell20,9601,043,112$12.63264.72428.11
SIMPSON TODD ECFO2007-09-26Sell32,2500$11.91384.1460.03
ROSENBERG MORRISSr. VP, Development2007-09-26Sell15,0000$11.93178.95459.09
DOBMEIER ERICChief Business Officer2007-09-20Sell1,9003,798$11.922.61460.5
DOBMEIER ERICChief Business Officer2007-09-20Sell19,1003,798$11.8225.38465.25
DOBMEIER ERICChief Business Officer2007-09-20Sell16,5003,798$11.65192.23472.53
DOBMEIER ERICChief Business Officer2007-09-20Sell18,1003,798$11.61210.14474.5
DOBMEIER ERICChief Business Officer2007-09-19Sell44,4003,798$11.54512.38477.99
LIPPMAN MARC EDirector2007-09-17Buy2,00010,000$10.6221.24528.06
SIEGALL CLAY BPresident and CEO2007-08-22Sell74,0001,053,168$11.09820.66501.44
SIEGALL CLAY BPresident and CEO2007-08-21Sell65,7001,127,168$10.99722.04506.92
SIEGALL CLAY BPresident and CEO2007-08-21Sell110,3001,079,168$11.141228.74498.74
TrailSmith Pamela AChief Scientific Officer2007-05-17Sell59,8916,940$10.23612.68552
ROSENBERG MORRISSr. VP, Development2007-05-17Sell25,0000$10.32258546.32
ROSENBERG MORRISSr. VP, Development2007-04-27Sell25,0000$9.54238.5599.16
Baker Bros. Capital (GP), LLCDirector2007-02-14Sell149,9304,957$8.761313.39661.42
Baker Biotech Capital (GP), LLDirector2007-02-14Sell999,7821,153,217$8.768758.09661.42
14159 capital (GP), LLCDirector2007-02-14Sell19,56175,598$8.76171.35661.42
Baker Brothers Life Sciences CDirector2007-02-14Sell1,599,7923,474,819$8.7614014.18661.42
Baker / Tisch Capital (GP), LLDirector2007-02-14Sell102,9353,998$8.76901.71661.42
14159 capital (GP), LLCDirector2007-02-14Sell19,56175,598$8.72170.57664.91
Baker Biotech Capital (GP), LLDirector2007-02-14Sell999,7821,153,217$8.728718.1664.91
Baker Bros. Capital (GP), LLCDirector2007-02-14Sell149,9304,957$8.721307.39664.91
Baker Brothers Life Sciences CDirector2007-02-14Sell1,599,7923,474,819$8.7213950.19664.91
AKKARAJU SRINIVASDirector2007-02-09Sell2,015,0000$8.5717268.55678.3
DOBMEIER ERICSr. VP, Corporate Development2007-02-09Sell50,0001,798$8.94447646.09
14159 capital (GP), LLCDirector, 10% Owner2006-08-14Buy85095,159$4.053.441546.91Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-14Buy37,0704,149,611$4.05150.131546.91Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-08-14Buy12,0801,535,999$4.0548.921546.91Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-11Buy110,2194,112,541$4.03444.181555.09Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-08-11Buy35,9171,523,919$4.03144.751555.09Link
14159 capital (GP), LLCDirector, 10% Owner2006-08-11Buy2,52994,309$4.0310.191555.09Link
14159 capital (GP), LLCDirector, 10% Owner2006-08-09Buy4,65291,239$4.0518.841546.91Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-09Buy202,7613,978,746$4.05821.181546.91Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-08-09Buy66,0731,480,319$4.05267.61546.91Link
14159 capital (GP), LLCDirector, 10% Owner2006-08-07Buy1,49286,587$4.036.011555.09Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-07Buy65,0203,775,985$4.03262.031555.09Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-02Buy23,5763,734,541$3.787.231702.7Link
14159 capital (GP), LLCDirector, 10% Owner2006-08-02Buy54185,636$3.721702.7Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-08-02Buy7,6831,400,741$3.728.431702.7Link
14159 capital (GP), LLCDirector, 10% Owner2006-06-29Buy8,43585,095$4.0333.991555.09Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-06-29Buy392,8333,710,965$4.031583.121555.09Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-06-29Buy129,9821,393,058$4.03523.831555.09Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-06-26Buy50,5351,263,076$4.02203.151559.2Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-06-26Buy152,9413,318,132$4.02614.821559.2Link
14159 capital (GP), LLCDirector, 10% Owner2006-06-26Buy3,29776,660$4.0213.251559.2Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-06-21Buy115,7053,165,191$4.02465.131559.2Link
14159 capital (GP), LLCDirector, 10% Owner2006-06-21Buy2,49473,363$4.0210.031559.2Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-06-21Buy38,2321,212,541$4.02153.691559.2Link
14159 capital (GP), LLCDirector, 10% Owner2006-06-13Buy33,07870,869$4132.311567.5Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-06-13Buy507,0211,174,309$42028.081567.5Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-06-13Buy1,534,4433,049,486$46137.771567.5Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-05-24Buy832,1351,515,043$5.254368.711170.48Link
14159 capital (GP), LLCDirector, 10% Owner2006-05-24Buy18,23037,791$5.2595.711170.48Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-05-24Buy278,650667,288$5.251462.911170.48Link
SIEGALL CLAY BPresident and CEO2005-09-13Sell73,0001,086,500$5.97435.811017.25Link
SIEGALL CLAY BPresident and CEO2005-09-09Sell24,0001,159,500$5.99143.761013.52Link
SIEGALL CLAY BPresident and CEO2005-08-02Sell103,0001,183,500$5.96613.881019.13Link
CARROLL TIMCFO2005-05-05Sell86,50062,861$5432.51234Link
Baker / Tisch Capital (GP), LLDirector, 10% Owner2005-05-04Buy67826,933$4.793.251292.48Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-05-04Buy94849,807$4.794.541292.48Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-05-04Buy1,22245,090$4.795.851292.48Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-05-04Buy6,305234,861$4.7930.21292.48Link
Baker Biotech Capital II (GP),Director, 10% Owner2005-05-04Buy6,627353,150$4.7931.741292.48Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2005-05-04Buy7,241388,638$4.7934.681292.48Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2005-05-04Buy1,44876,887$4.796.941292.48Link
14159 capital (GP), LLCDirector, 10% Owner2005-05-04Buy53119,561$4.792.541292.48Link
14159 capital (GP), LLCDirector, 10% Owner2005-04-29Buy6,39319,030$425.571567.5Link
Baker / Tisch Capital (GP), LLDirector, 10% Owner2005-04-29Buy8,41026,255$433.641567.5Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2005-04-29Buy89,394381,397$4357.581567.5Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-04-29Buy14,73443,868$458.941567.5Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2005-04-29Buy17,76675,439$471.061567.5Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-04-29Buy11,54248,859$446.171567.5Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-04-29Buy76,759228,556$4307.041567.5Link
Baker Biotech Capital II (GP),Director, 10% Owner2005-04-29Buy81,750346,523$43271567.5Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2005-03-30Buy12,040292,003$4.9659.721244.76Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2005-03-30Buy10,816264,773$4.9653.651244.76Link
BAKER TISCH CAPITAL GP LLCDirector, 10% Owner2005-03-30Buy1,13417,845$4.965.621244.76Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2005-03-30Buy2,34457,673$4.9611.631244.76Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-03-30Buy1,50637,317$4.967.471244.76Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-03-30Buy9,617151,797$4.9647.71244.76Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-03-30Buy1,84329,134$4.969.141244.76Link
14159 Capital (GP, LLCDirector, 10% Owner2005-03-30Buy80012,637$4.963.971244.76Link
BAKER TISCH CAPITAL GP LLCDirector, 10% Owner2005-03-29Buy96816,711$4.884.721266.8Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2005-03-29Buy2,00155,329$4.889.761266.8Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-03-29Buy1,28535,811$4.886.271266.8Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2005-03-29Buy9,229253,957$4.8845.041266.8Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2005-03-29Buy10,273279,963$4.8850.131266.8Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-03-29Buy8,205142,180$4.8840.041266.8Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-03-29Buy1,57327,291$4.887.681266.8Link
14159 Capital (GP, LLCDirector, 10% Owner2005-03-29Buy68211,837$4.883.331266.8Link
BAKER TISCH CAPITAL GP LLCDirector, 10% Owner2005-03-23Buy15,74315,743$4.9978.561236.67Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2005-03-23Buy150,679244,728$4.99751.891236.67Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2005-03-23Buy167,773269,690$4.99837.191236.67Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2005-03-23Buy32,67053,328$4.99163.021236.67Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-03-23Buy20,98434,526$4.99104.711236.67Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-03-23Buy63,376133,975$4.96314.341244.76Link
14159 Capital (GP, LLCDirector, 10% Owner2005-03-23Buy5,25111,155$4.9626.041244.76Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-03-23Buy12,16625,718$4.9660.341244.76Link
POWELL MICHAELDirector2004-12-16Sell56,500685,892$7395.5852.86Link
POWELL MICHAELDirector2004-12-07Sell22,450742,392$7.03157.82848.79Link
POWELL MICHAELDirector2004-12-06Sell135,000764,842$7.06953.1844.76Link
POWELL MICHAELDirector2004-12-01Sell32,500899,842$6.94225.55861.1Link
POWELL MICHAELDirector2004-11-16Sell54,000932,342$6.9372.6866.67Link
POWELL MICHAELDirector2004-11-15Sell146,000986,342$6.77988.42885.23Link
POWELL MICHAELDirector2004-09-29Sell50,0001,131,354$6.67333.5900Link
POWELL MICHAELDirector2004-09-24Sell10,0001,181,354$6.9269.2863.87Link
POWELL MICHAELDirector2004-09-23Sell94,4881,191,354$6.83645.35876.57Link
POWELL MICHAELDirector2004-09-17Sell55,5001,285,842$6.71372.41894.04Link
POWELL MICHAELDirector2004-09-02Sell26,0001,341,342$6.61171.86909.08Link
POWELL MICHAELDirector2004-08-27Sell35,0001,367,342$6.81238.35879.44Link
POWELL MICHAELDirector2004-08-24Sell121,0001,402,342$6.81824.01879.44Link
POWELL MICHAELDirector2004-08-19Sell44,0001,523,342$6.75297888.15Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2004-08-12Buy32,72392,120$5.55181.611101.8Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2004-08-12Buy45,745188,823$5.49251.141114.94Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2004-08-12Buy17,65029,619$5.495.311135.19Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2004-08-06Buy21,88962,682$5.53121.051106.15Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2004-08-06Buy4,21311,969$5.5323.31106.15Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2004-08-06Buy20,73459,397$5.53114.661106.15Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2004-08-04Buy38,66338,663$5.72221.151066.08Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2004-08-04Buy40,79340,793$5.72233.341066.08Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2004-08-04Buy7,7567,756$5.7244.361066.08Link
POWELL MICHAELDirector2004-06-29Sell28,5001,567,342$7.03200.36848.79Link
CARROLL TIMCFO2004-06-28Sell60,000152,361$7.04422.4847.44Link
POWELL MICHAELDirector2004-06-25Sell121,5001,595,842$7.08860.22842.09Link
POWELL MICHAELDirector2004-06-22Sell80,0001,717,342$7.12569.6836.8Link
CARROLL TIMCFO2004-05-10Sell8,600212,361$8.2270.69711.44Link
DOBMEIER ERICV. P., Corporate Affairs2004-05-05Sell15,000300$8.59128.85676.48Link
POWELL MICHAELDirector2004-03-09Sell65,0001,797,342$10.42677.3540.12Link
POWELL MICHAELDirector2003-12-30Sell7,0001,862,342$8.962.3649.44Link
POWELL MICHAELDirector2003-12-23Sell87,2501,869,342$7.22629.95823.82Link
POWELL MICHAELDirector2003-12-09Sell56,0001,956,592$7.02393.12850.14Link
CARROLL TIMCFO2003-12-05Sell80,000220,961$6.63530.4906.03Link
POWELL MICHAELDirector2003-12-04Sell11,7032,012,592$6.5676.77916.77Link
POWELL MICHAELDirector2003-12-02Sell153,0002,024,295$6.33968.49953.71Link
SIEGALL CLAY BPresident and CEO2003-12-02Sell50,0001,291,500$6.47323.5930.91Link
FELL H PERRYChairman2003-12-02Sell50,0001,294,000$6.47323.5930.91Link
SIEGALL CLAY BPresident and CEO2003-11-26Sell4,5001,341,500$6.4428.98935.71Link
FELL H PERRYChairman2003-11-26Sell4,5001,344,000$6.4428.98935.71Link
POWELL MICHAELDirector2003-11-26Sell108,5002,177,295$6.27680.3963.8Link
SIEGALL CLAY BPresident and CEO2003-11-24Sell56,5001,346,000$6.52368.38923.01Link
FELL H PERRYChairman2003-11-24Sell56,5001,348,500$6.52368.38923.01Link
HELLSTROM KARL ERIKDirector2003-11-19Sell66,500700,000$6.69444.89897.01Link
POWELL MICHAELDirector2003-11-18Sell414,4782,285,795$62486.871011.67Link
HELLSTROM KARL ERIKDirector2003-11-18Sell133,500766,500$6.48865.08929.32Link
SIEGALL CLAY BPresident and CEO2003-09-15Sell10,0001,402,500$5.9591030.51Link
FELL H PERRYChairman2003-09-15Sell10,0001,405,000$5.9591030.51Link
SIEGALL CLAY BPresident and CEO2003-09-11Sell47,5001,412,500$6.05287.381002.48Link
FELL H PERRYChairman2003-09-11Sell47,5001,415,000$6.05287.381002.48Link
SIEGALL CLAY BPresident and CEO2003-09-08Sell31,5001,460,000$6.18194.67979.29Link
FELL H PERRYChairman2003-09-08Sell31,5001,462,500$6.18194.67979.29Link
SENTER PETERVice President, Chemistry2003-08-21Sell19,60068,148$5.27103.291165.65Link
SING AMYSr. Director Medical Affairs2003-08-18Sell20,00052,107$5.09101.81210.41Link
LIPPMAN MARC EDirector2003-08-14Buy15,00052,500$4.8873.21266.8Link
SING AMYSr. Director Medical Affairs2003-08-04Sell5,00072,107$4.723.51319.15Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

To find out why GuruFocus thinks data on insider trade are interesting, please read:
Also See GuruFocus Insider Trade Screener:

Get WordPress Plugins for easy affiliate links on Stock Tickers and Guru Names | Earn affiliate commissions by embedding GuruFocus Charts
GuruFocus Affiliate Program: Earn up to $400 per referral. ( Learn More)
FEEDBACK