Switch to:

Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Samuel F. Colin, M.D.N/A500,0000.48%2014-05-01
Mr. Seth H.Z. FischerN/A486,0800.46%2016-09-26
Mr. Svai SanfordN/A128,3590.12%2015-08-03
Neil Gesundheit,M.D.N/A127,6530.12%2005-01-14
Leland F. WilsonN/A119,9250.11%2013-01-25
Mr. Santosh T VargheseChief Medical Officer, 10% Owner88,256less than 0.1%2016-10-01
Dr. Ernest Mario,PhDN/A81,125less than 0.1%2013-05-29
Mark B. LoganN/A74,125less than 0.1%2013-01-25
Terry M. NidaN/A65,727less than 0.1%2006-12-01
Mr. John L. SlebirN/A59,893less than 0.1%2015-07-01

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Varghese Santosh TChief Medical Officer, 10% Owner2016-10-01Sell71088,256$1.140.8122.8188,256 (Direct)
Varghese Santosh TChief Medical Officer2016-08-02Sell12,55988,966$1.0713.4430.8488,966 (Direct)
Varghese Santosh TVP, Medical & Reg Affairs2016-07-01Sell366101,525$1.210.4415.7101,525 (Direct)
Varghese Santosh TChief Medical Officer2016-04-07Sell329101,891$1.650.54-15.15101,891 (Direct)
NORTH TIDE CAPITAL, LLC10% Owner2016-04-01Buy2,16013,587,460$1.43.020
13,587,460 (See Footnote(,,))
NORTH TIDE CAPITAL, LLC10% Owner2016-03-31Buy383,30013,585,300$1.29494.468.53
13,585,300 (See Footnote(,,))
NORTH TIDE CAPITAL, LLC10% Owner2016-03-28Buy202,00013,202,000$1.12226.2425
13,202,000 (See Footnote(F1,))
NORTH TIDE CAPITAL, LLC10% Owner2016-03-16Buy500,00013,000,000$1.2160515.7
13,000,000 (See Footnotes(F1,F2))
Varghese Santosh TChief Medical Officer2016-01-13Sell1,553102,220$0.951.4847.37102,220 (Direct)
Slebir John LSVP, Business Development & GC2015-07-01Sell9,93359,893$2.221.85-36.3659,893 (Direct)
Varghese Santosh TVP, Medical & Reg Affairs2015-07-01Sell8,51435,373$2.218.73-36.3635,373 (Direct)
Varghese Santosh TVP, Medical & Reg Affairs2015-07-01Sell7,89941,234$2.3218.33-39.6641,234 (Direct)
Slebir John LSVP, Business Development & GC2015-07-01Sell9,21563,584$2.3221.38-39.6663,584 (Direct)
Day WesleyVP, Clinical Development2015-07-01Sell7,88149,118$2.3218.28-39.6649,118 (Direct)
Day WesleyVP, Clinical Development2015-01-29Sell47256,999$2.781.31-49.6456,999 (Direct)
Slebir John LSVP, Business Development & GC2015-01-29Sell63072,799$2.781.75-49.6472,799 (Direct)
MARSH GUY PVP, US Operations & GM2015-01-29Sell23831,487$2.780.66-49.6431,487 (Direct)
Sanford Svai SCFO & Chief Accounting Officer
(Click for the stocks that their CFOs have bought)
2015-01-29Sell47265,559$2.781.31-49.6465,559 (Direct)
MARSH GUY PVP, US Operations & GM2015-01-29Sell63330,854$3.041.92-53.9530,854 (Direct)
NORTH TIDE CAPITAL, LLC10% Owner2015-01-08Buy500,00037,039,570$3.121560-55.13
12,382,470 (See Footnotes(F1,F3))
12,500,000 (See Footnotes(F1,F2))
12,157,100 (See Footnote2(F1,F3))
NORTH TIDE CAPITAL, LLC10% Owner2015-01-06Buy476,80012,000,000$3.041449.47-53.95
12,000,000 (See Footnote)
NORTH TIDE CAPITAL, LLC10% Owner2015-01-02Buy523,20011,523,200$2.91517.28-51.72
11,523,200 (See Footnote)
Slebir John LSVP, Business Development & GC2015-01-01Sell2,97344,555$3.049.04-53.9544,555 (Direct)
Day WesleyVP, Clinical Development2015-01-01Sell2,54946,569$3.047.75-53.9546,569 (Direct)
Fischer Seth H.Z.CEO
(Click for the stocks that their CEOs have bought)
2014-03-11Buy3,0803,080$6.0718.7-76.943,080 (Direct)
DENNER ALEXANDER JDirector2013-11-11Buy566,8442,573,943$8.594869.19-83.7
2,573,943 (See footnotes(F4,F5))
MORRIS TIMOTHY EVP, Finance and CFO2013-09-05Sell10,6540$11.95127.32-88.28Link
ASTRUE MICHAEL JDirector2013-09-04Buy10,00010,000$11.96119.6-88.2910,000 (Direct)
BIRO JON CSEE REMARKS2013-06-27Buy2,0004,000$12.8525.7-89.114,000 (Direct)
MARIO ERNESTDirector2013-05-29Buy15,00081,125$14.68220.2-90.4681,125 (Direct)
MARIO ERNESTDirector2012-08-20Buy5,00045,000$20.75103.75-93.2545,000 (Direct)
CASAMENTO CHARLES JDirector2012-08-20Sell8,00066,000$20.63165.04-93.2166,000 (Direct)
LOGAN MARK BDirector2012-08-14Sell49,81653,000$23.131152.24-93.9553,000 (Direct)
SHORTLIFFE LINDA M DAIRIKIDirector2012-08-14Sell18,0005,000$22.72408.96-93.845,000 (Direct)
LOGAN MARK BDirector2012-08-13Sell18,18453,000$21.81396.59-93.5853,000 (Direct)
SHORTLIFFE LINDA M DAIRIKIDirector2012-08-13Sell45,0005,000$21.72977.4-93.555,000 (Direct)
MARIO ERNESTDirector2012-08-10Buy20,00040,000$21.74434.8-93.5640,000 (Direct)
Slebir John LVP, General Counsel2012-07-18Sell10,0004,126$30.36303.6-95.394,126 (Direct)
TAM PETER YPresident2012-07-18Sell25,00037,629$30.95773.75-95.4837,629 (Direct)
Day WesleyVP, Clinical Research2012-07-18Sell16,8000$30.36510.05-95.39Link
MORRIS TIMOTHY EVP, Finance and CFO2012-07-18Sell25,0000$30.36759-95.39Link
WILSON LELAND FCEO2012-07-18Sell100,000119,112$30.363036-95.39119,112 (Direct)
MARSH GUY PVP, Operations and General Mgr2012-07-18Sell36,1912,074$30.361098.76-95.392,074 (Direct)
MILLER MICHAEL PATRICKChief Commercial Officer2012-07-18Sell25,0007,943$30.36759-95.397,943 (Direct)
MILLER MICHAEL PATRICKChief Commercial Officer2012-06-27Sell25,0007,943$28.08702-95.017,943 (Direct)
WILSON LELAND FCEO2012-06-27Sell50,000119,112$281400-95119,112 (Direct)
TAM PETER YPresident2012-06-19Sell20,00037,629$27.25545-94.8637,629 (Direct)
TAM PETER YPresident2012-06-18Sell20,00037,629$26.45529-94.7137,629 (Direct)
TAM PETER YPresident2012-06-14Sell60,00037,629$25.251515-94.4637,629 (Direct)
TAM PETER YPresident2012-06-14Sell236,25097,629$25.285972.4-94.4697,629 (Direct)
MILLER MICHAEL PATRICKChief Commercial Officer2012-06-12Sell25,0007,943$25625-94.47,943 (Direct)
WILSON LELAND FCEO2012-06-11Sell50,000119,112$25.181259-94.44119,112 (Direct)
LOGAN MARK BDirector2012-03-16Sell14,00048,000$20.32284.48-93.1148,000 (Direct)
MARSH GUY PVP, Operations & General Mgr.2012-03-15Sell6,6051,106$20.31134.15-93.111,106 (Direct)
CASAMENTO CHARLES JDirector2012-03-12Sell37,00061,000$20.14745.18-93.0561,000 (Direct)
Perry LeeVP & Chief Accounting Officer2012-03-09Sell87,6230$20.961836.58-93.32Link
SHORTLIFFE LINDA M DAIRIKIDirector2012-03-08Sell52,0000$21.51118-93.49Link
MORRIS TIMOTHY ESVP, Finance and CFO2012-02-27Sell329,3580$21.267002.15-93.41Link
WILSON LELAND FCEO2012-02-27Sell50,000118,271$251250-94.4118,271 (Direct)
MARSH GUY PVP, Operations and General Mgr2012-02-27Sell47,0787,711$22.931079.5-93.897,711 (Direct)
WILSON LELAND FCEO2012-02-23Sell150,000118,271$20.693103.5-93.23118,271 (Direct)
MARSH GUY PVP, Operations & General Mgr.2012-02-23Sell86,7777,711$20.71796.28-93.247,711 (Direct)
Day WesleyVP, Clinical Development2012-02-23Sell79,95816,800$20.691654.33-93.2316,800 (Direct)
Perry LeeVP & Chief Accounting Officer2012-02-23Sell171,8320$20.693555.2-93.23Link
TAM PETER YPresident2012-01-11Sell27,01496,221$12324.17-88.3396,221 (Direct)
TAM PETER YPresident2012-01-10Sell12,386123,235$12148.63-88.33123,235 (Direct)
Perry LeeVP & Chief Accounting Officer2012-01-09Sell39,7000$11.75466.48-88.09Link
Day WesleyVP, Clinical Development2012-01-09Sell30,00016,800$11.5345-87.8316,800 (Direct)
Day WesleyVP, Clinical Development2011-11-11Sell23,44216,800$9.87231.37-85.8216,800 (Direct)
Day WesleyVP, Clinical Development2010-12-17Sell70,60016,800$9.54673.52-85.32Link
LOGAN MARK BDirector2010-12-17Sell38,00048,000$9.34354.92-85.01Link
Day WesleyVP, Clinical Development2010-12-17Sell66,60020,800$9.54635.36-85.32Link
TAM PETER YPresident2010-12-16Sell10,000126,775$9.2892.8-84.91Link
SHORTLIFFE LINDA M DAIRIKIDirector2010-12-15Sell8,0000$9.3174.48-84.96Link
WILSON LELAND FCEO2010-12-15Sell62,000115,966$9.16567.92-84.72Link
MORRIS TIMOTHY ESVP, Finance & CFO2010-06-14Sell26,2500$12.16319.2-88.49Link
WILSON LELAND FCEO2010-05-18Sell50,00076,772$13650-89.23Link
SHORTLIFFE LINDA M DAIRIKIDirector2010-03-11Sell8,0000$9.2674.08-84.88Link
MARSH GUY PVP, Operations & General Mgr.2009-09-30Sell2,6303,701$10.8428.51-87.08Link
MARSH GUY PVP, Operations & General Mgr.2009-09-25Sell2,0843,701$10.5121.9-86.68Link
MARSH GUY PVP, Operations & General Mgr.2009-09-11Sell34,5823,701$12.05416.71-88.38Link
MARSH GUY PVP, Operations & General Mgr.2009-09-10Sell70,0003,701$11.46802.2-87.78Link
WILSON LELAND FPresident & CEO2009-09-09Sell200,000103,609$11.232246-87.53Link
Perry LeeVP & Chief Accounting Officer2009-09-09Sell12,0000$12.1145.2-88.43Link
MARSH GUY PVP, Operations & General Mgr.2009-08-31Sell2,6303,701$6.2716.49-77.67Link
MARSH GUY PVP, Operations & General Mgr2009-08-24Sell5213,701$6.783.53-79.35Link
MARSH GUY PVP, Operations & General Mgr.2009-07-31Sell54,8313,701$7.53412.88-81.41Link
MARSH GUY PVP, Operations & General Mgr.2009-07-27Sell3003,701$7.52.25-81.33Link
MARSH GUY PVP, Operations & General Mgr.2009-07-23Sell5213,701$6.973.63-79.91
MARSH GUY PVP, Operations & General Mgr.2009-07-23Sell5213,701$6.973.63-79.91
MARSH GUY PVP, Operations & General Mgr.2009-07-23Sell5213,701$6.973.63-79.91Link
WILSON LELAND FPresident & CEO2009-07-22Sell50,000303,609$7350-80
WILSON LELAND FPresident & CEO2009-07-22Sell50,000303,609$7350-80
WILSON LELAND FPresident & CEO2009-07-22Sell50,000303,609$7350-80Link
MARSH GUY PVP, Operations & General Mgr.2009-06-30Sell2,6313,701$615.79-76.67
MARSH GUY PVP, Operations & General Mgr.2009-06-30Sell2,6313,701$615.79-76.67
MARSH GUY PVP, Operations & General Mgr.2009-06-26Sell11,8673,701$671.2-76.67
MARSH GUY PVP, Operations & General Mgr.2009-06-15Sell39,1583,701$6.02235.73-76.74
WILSON LELAND FPresident & CEO2009-06-12Sell50,000353,609$6.1305-77.05
SHORTLIFFE LINDA M DAIRIKIDirector2008-12-15Sell32,0000$5.92189.44-76.35
WILSON LELAND FPresident & CEO, Director2008-12-12Sell30,000402,032$6.42192.6-78.19
PLACE VIRGIL AChief Scientific Officer, Director2008-09-11Sell5,950434,049$953.55-84.44
WILSON LELAND FPresident & CEO, Director2008-09-02Sell50,000280,773$8.55427.5-83.63
MARSH GUY PVP, Operations & General Mgr.2008-08-12Sell188,1383,701$8.481595.41-83.49
WILSON LELAND FPresident & CEO, Director2008-05-23Sell85,585290,617$6.5556.3-78.46
Day WesleyVP, Clinical Research2008-05-14Buy3,29716,843$4.1713.75-66.43
TAM PETER YSenior VP, Product &2008-05-14Buy3,72772,994$4.1715.54-66.43
WILSON LELAND FPresident & CEO, Director2008-05-14Buy1,295376,202$4.175.4-66.43
WILSON LELAND FPresident and CEO, Director2008-04-07Sell14,415374,907$6.593.7-78.46
WILSON LELAND FPresident & CEO, Director2008-01-16Sell65,721394,601$5.99393.67-76.63
WILSON LELAND FPresident & CEO, Director2008-01-14Sell7,500460,322$645-76.67
WILSON LELAND FPresident and CEO, Director2007-11-28Sell44,228466,002$5.3234.41-73.58
WILSON LELAND FPresident and CEO, Director2007-11-28Sell95,375414,855$5.32507.4-73.68
WILSON LELAND FPresident & CEO, Director2007-11-28Sell94,375420,134$5.32502.08-73.68
Day WesleyVP, Clinical Research2007-11-14Buy3,10413,546$4.2313.13-66.9
TAM PETER YSenior VP, Product &2007-11-14Buy1,49569,267$4.236.32-66.9
WILSON LELAND FPresident & CEO, Director2007-11-14Buy1,216462,197$4.235.14-66.9
WILSON LELAND FPresident & CEO, Director2007-10-22Sell4,279456,702$5.523.53-74.55
PLACE VIRGIL AChief Scientific Officer2007-09-07Sell7,781422,514$5.139.68-72.55
PLACE VIRGIL AChief Scientific Officer2007-09-06Sell25,000430,295$5.15128.75-72.82
PLACE VIRGIL AChief Scientific Officer2007-09-05Sell10,000440,295$5.2152.1-73.13
PLACE VIRGIL AChief Scientific Officer2007-09-04Sell20,000450,295$5.3106-73.58
PLACE VIRGIL AChairman & CSO2007-08-30Sell10,000470,295$5.2952.9-73.53
PLACE VIRGIL AChairman & CSO2007-08-29Sell15,000480,295$5.1677.4-72.87
PLACE VIRGIL AChairman & CSO2007-08-27Sell20,000510,295$5.11102.2-72.6
WILSON LELAND FPresident & CEO2007-08-09Sell15,000460,981$5.5382.95-74.68
WILSON LELAND FPresident & CEO2007-08-01Sell7,500475,981$5.6242.15-75.09
WILSON LELAND FPresident & CEO2007-04-30Sell200,000481,820$5.581116-74.91
NIDA TERRYVP, Worldwide Marketing/2006-12-01Sell30,00065,727$4120-65
WILSON LELAND FDirector2006-11-30Sell44,999681,820$4.09184.05-65.77
Day WesleyVP, Clinical Research2006-03-02Buy4,0004,000$3.413.6-58.82Link
TAM PETER YSenior VP, Product &2005-10-31Buy3,30055,803$2.317.62-39.39Link
DIETRICH JOHN WVice President, R & D2005-10-31Buy1,38016,374$2.313.19-39.39Link
NIDA TERRYVP, Worldwide Marketing/2005-10-31Sell46,87555,981$3140.63-53.33Link
DIETRICH JOHN WVice President, R & D2005-04-29Buy1,27014,994$2.32.92-39.13Link
NIDA TERRYVP, Worldwide Marketing/2005-04-29Buy2,74252,787$2.36.31-39.13Link
TAM PETER YSenior VP, Commerical &2005-04-29Buy5,43152,503$2.312.49-39.13Link
TAM PETER YSenior VP, Commerical &2004-10-29Buy2,88747,072$3.5910.36-61Link
NIDA TERRYVP, Worldwide Marketing/2004-10-29Buy1,71550,045$3.596.16-61Link
NICKEL JAMES RVice President, Clinical2004-10-29Buy2,9624,962$3.5910.63-61Link
DIETRICH JOHN WVice President, R & D2004-10-29Buy1,10013,724$3.593.95-61Link
TAM PETER YVP, Business Planning2004-04-30Buy2,84344,185$3.239.18-56.66Link
STRAUSS LARRY JVice President, Finance & CFO2004-04-30Buy774774$3.232.5-56.66Link
DIETRICH JOHN WVice President, R & D2004-04-30Buy1,45812,624$3.234.71-56.66Link
DIETRICH JOHN WVice President, R & D2004-02-23Sell1,45011,166$5.427.86-74.17Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

To find out why GuruFocus thinks data on insider trade are interesting, please read:
Also See GuruFocus Insider Trade Screener:

Get WordPress Plugins for easy affiliate links on Stock Tickers and Guru Names | Earn affiliate commissions by embedding GuruFocus Charts
GuruFocus Affiliate Program: Earn up to $400 per referral. ( Learn More)
FEEDBACK