PRIMECAP Management Buys BioNTech SE, LivaNova PLC, Raymond James Financial Inc, Sells Insulet Corp, Alkermes PLC, Linde PLC

• New Purchases: BNTX, CALA, FGEN, BIDU, ARE, CYBR, RPD,
• Added Positions: BIIB, BMRN, V, LIVN, RJF, INTC, NOK, ORCL, EPZM, MA, RYTM, BMY, ETFC, ACM, PLT, TXT, PINS, CRWD, MO, NBL, C, COG, ERIC, NKTR, LASR, ALTR, FSCT, BJ, ADSK, NTNX, BGNE, WVE, GKOS, CCJ, QSR, MTLS, ANET, PANW, CPRI, FTI, FOLD, CMCSA, TDG, MATX, SLB, GD, MCD, NWL,
• Reduced Positions: GOOG, GOOGL, PODD, ADBE, SGEN, MSFT, ALKS, LIN, CRM, JPM, EBAY, OLED, CME, NVDA, WAT, BA, QCOM, SPLK, SPPI, DE, MU, S, ABT, MDT, RCL, SNE, AMZN, J, PNR, CHGG, XNCR, ASML, AXP, VIAC, TRMB, BOOT, PYPL, GLW, FARO, HPQ, MFGP, ARLO, ALB, CRNC, MBII, LB, ALC, HLT, TW, REZI, TWOU, RUBI, BE, HUBS, AXGT, PS, MYOK, MREO, NGVT, SWN, JBL, IMAX, NOV, NUAN, GIL, PBH, RMBS, BB, ETM, ASNA, STZ, ANGI, DXC, AAXN, TER, CVGW, ARNA, ALGT, SCOR, PRO, VMW, ABUS, SREV,
• Sold Out: SPR, PVTL, CMA, ADVM, ZM,

For the details of PRIMECAP Management's stock buys and sells, go to https://www.gurufocus.com/guru/primecap+management/current-portfolio/portfolio

1. Eli Lilly and Co (LLY) - 43,124,718 shares, 4.11% of the total portfolio. Shares added by 0.68%
2. Adobe Inc (ADBE) - 15,161,190 shares, 3.63% of the total portfolio. Shares reduced by 4.89%
3. Microsoft Corp (MSFT) - 30,982,043 shares, 3.54% of the total portfolio. Shares reduced by 3.71%
4. Biogen Inc (BIIB) - 15,189,481 shares, 3.27% of the total portfolio. Shares added by 6.52%
5. Amgen Inc (AMGN) - 18,297,015 shares, 3.20% of the total portfolio. Shares added by 0.53%

PRIMECAP Management initiated holding in BioNTech SE. The purchase prices were between $12.75 and $36.91, with an estimated average price of $22.59. The stock is now traded at around $31.07. The impact to a portfolio due to this purchase was 0.05%. The holding were 2,128,182 shares as of .

PRIMECAP Management initiated holding in Calithera Biosciences Inc. The purchase prices were between $2.52 and $6.17, with an estimated average price of $3.83. The stock is now traded at around $6.81. The impact to a portfolio due to this purchase was 0.04%. The holding were 9,488,000 shares as of .

PRIMECAP Management initiated holding in FibroGen Inc. The purchase prices were between $34.58 and $48.06, with an estimated average price of $40.98. The stock is now traded at around $44.88. The impact to a portfolio due to this purchase was 0.03%. The holding were 1,043,374 shares as of .

PRIMECAP Management initiated holding in Baidu Inc. The purchase prices were between $99.53 and $128.83, with an estimated average price of $114.18. The stock is now traded at around $135.20. The impact to a portfolio due to this purchase was 0.01%. The holding were 153,605 shares as of .

PRIMECAP Management initiated holding in CyberArk Software Ltd. The purchase prices were between $96.94 and $126.35, with an estimated average price of $112.62. The stock is now traded at around $117.74. The impact to a portfolio due to this purchase was less than 0.01%. The holding were 28,300 shares as of .

PRIMECAP Management initiated holding in Alexandria Real Estate Equities Inc. The purchase prices were between $151.9 and $162.52, with an estimated average price of $157.81. The stock is now traded at around $174.70. The impact to a portfolio due to this purchase was less than 0.01%. The holding were 26,500 shares as of .

PRIMECAP Management added to a holding in Raymond James Financial Inc by 36.15%. The purchase prices were between $76.44 and $91.32, with an estimated average price of $86.81. The stock is now traded at around $99.05. The impact to a portfolio due to this purchase was 0.05%. The holding were 3,135,150 shares as of .

PRIMECAP Management added to a holding in LivaNova PLC by 180.84%. The purchase prices were between $68.92 and $85.27, with an estimated average price of $76.02. The stock is now traded at around $70.56. The impact to a portfolio due to this purchase was 0.05%. The holding were 1,440,600 shares as of .

PRIMECAP Management added to a holding in Nokia Oyj by 72.03%. The purchase prices were between $3.35 and $5.23, with an estimated average price of $3.91. The stock is now traded at around $4.32. The impact to a portfolio due to this purchase was 0.04%. The holding were 35,918,600 shares as of .

PRIMECAP Management added to a holding in Mastercard Inc by 256.65%. The purchase prices were between $260.85 and $300.74, with an estimated average price of $282.5. The stock is now traded at around $339.62. The impact to a portfolio due to this purchase was 0.04%. The holding were 290,574 shares as of .

PRIMECAP Management added to a holding in Rhythm Pharmaceuticals Inc by 747.73%. The purchase prices were between $19.53 and $25.5, with an estimated average price of $22.27. The stock is now traded at around $17.77. The impact to a portfolio due to this purchase was 0.03%. The holding were 2,093,691 shares as of .

PRIMECAP Management added to a holding in Pinterest Inc by 165.10%. The purchase prices were between $17.45 and $27.37, with an estimated average price of $21.44. The stock is now traded at around $23.69. The impact to a portfolio due to this purchase was 0.01%. The holding were 1,690,800 shares as of .

PRIMECAP Management sold out a holding in Spirit AeroSystems Holdings Inc. The sale prices were between $72.88 and $92.04, with an estimated average price of $82.43.

PRIMECAP Management sold out a holding in Pivotal Software Inc. The sale prices were between $14.89 and $15.05, with an estimated average price of $14.98.

PRIMECAP Management sold out a holding in Comerica Inc. The sale prices were between $62.33 and $72.76, with an estimated average price of $68.8.

PRIMECAP Management sold out a holding in Zoom Video Communications Inc. The sale prices were between $62 and $76.99, with an estimated average price of $68.76.

PRIMECAP Management sold out a holding in Adverum Biotechnologies Inc. The sale prices were between $5.12 and $12.22, with an estimated average price of $8.95.