Great Lakes Advisors, Llc Buys RenaissanceRe Holdings, Agios Pharmaceuticals Inc, Zillow Group Inc, Sells Alphabet Inc, MetLife Inc, Sysco Corp

• New Purchases: RNR, AGIO, Z, AEE, IPHI, CDLX, CUZ, WPX, CNNE, SGMO, REXR, BRKS, AMBA, FWONK, IRBT, VICR, AIN, ARNA, CYRX, TWOU, PAR, ARE, BLUE, ALB, ACLS, LLNW, STOR, HOG, HXL, WD, RLGY, REYN, OXY, ACA, EXAS, MAC, BERY, ADS, DPZ, OTRK, MAR, SWKS, TIF, SPR, PLAY, YUM, PRF, AVB, TFC, HCSG, SERV, COF, IPGP, BXP, CPT, IT, MAA, RPM, FOX, SCIU, CNS, JW.A, KRC, KIM, LII, MAS, NFG, BPOP, SHW, VRTX, WRB, TDG, WYND, TMUS, DNKN, HZNP, FOXF, WING, EFAV, SPYD, UBS, CDEVY, DSEEY, KGFHY, INFN, NWG, GEAHF, KGFHF, HKSHF, CDEVF, SNLAF, RYS1, AIBRF, SKLKY, SUTNY, CAIXY, ISSDY, SOUHY, SHTLF, ALPKF, BKRIY, AIBGY,
• Added Positions: MKSI, CMCSA, BLK, SLG, DIS, PNC, CRUS, NATI, IRM, OLLI, STZ, DLR, MCO, DRQ, BUD, PYPL, PM, AIV, MCD, NYCB, SPTM, PEG, IEFA, KSU, RL, ZBH, HP, NSC, ADBE, BRK.B, EFX, VNO, WWE, BURL, ADSK, CVX, XRAY, EW, TDY, DOCU, IEMG, IWF, PLD, VSAT, PNR, SRC, TTD, ASH, AVY, BRKR, CAT, CRL, CHE, CCI, FRT, JLL, MANH, SPGI, POWI, LIN, ROL, SBUX, FAF, COR, QTS, ALLE, VRNS, SITE, OKTA, ABMD, AXS, BYD, CHH, CCOI, CGNX, COHR, HIW, HRC, NVDA, NEOG, RDS.A, SYK, WTS, WST, AWI, PCRX, FIVE, MEDP, FND, IVV, IWM, SPEM, AOS, AMD, CRMT, AMT, BCPC, BXS, BF.B, FIS, CFR, FBC, DIN, IEX, LPSN, MKC, NFLX, NKE, ORLY, OXM, PCH, SSB, SSD, TROW, TXRH, USPH, RTX, URBN, PZN, BEAT, ADUS, AVGO, H, PDM, FN, BKU, KN, ZEN, XENT, NVRO, PGRE, GNL, FHB, LW, WHD, WH, VEA, AFL, ABC, ADP, BMY, CVCO, CME, CBSH, XOM, FFIN, FELE, GPN, LHX, IBM, ICE, PRA, SBAC, CRM, UMPQ, MTN, VRSN, VZ, WBA, RDS.B, BR, PODD, VRSK, XYL, NOW, RNG, VEEV, IJJ, IJS, SCHH, VB, VO, VTV, VUG, VWO, VXF, XLE,
• Reduced Positions: GOOG, MET, ABBV, BIIB, MDLZ, LRCX, SCZ, AMP, GL, PG, MRK, BKNG, SPSC, DFS, COUP, ENS, ZION, NDSN, TXN, WM, EXPE, VMI, BMRN, BDN, INTC, ORCL, UNP, AMED, NEE, SGEN, UNH, WMT, PINC, APD, PRGS, O, TJX, FIBK, VNQI, MMM, AXP, BA, CVS, LMT, MCK, STE, TRIP, EFA, AMZN, HAIN, IBKC, BAC, LMNX, PCAR, TOL, CVNA, CB, AYI, C, CMI, PEP, IRTC, AAPL, BWA, KO, GE, HAS, JPM, MSFT, PRU, SLB, EEM, IWD, SPY, BDX, BSX, CMS, CL, DHR, KMB, MSM, PPG, PDCO, PAYX, PRAA, TGT, TMO, WAB, WLTW, SPB, CHTR, PSX, VNQ, AON, OZK, CSX, ATGE, DCI, DD, ETN, ECL, LLY, PEAK, HMN, ISBC, JNJ, JEF, NEU, UNF, UPS, V, FTNT, DG, SSNC, TRUP, LBRDK, DESP, FTDR, IWR, SPDW, XLK, T, ABT, ALL, ALNY, MO, AMGN, AVT, BAX, BCO, CDNS, CNC, CI, CR, DECK, DE, DXCM, EME, FISV, GD, GIS, GOOGL, WELL, HUM, ITW, INTU, JKHY, JCI, MAT, MDT, MTD, MOH, MPWR, NOV, NJR, JWN, ES, PSB, PFE, RSG, RMD, RGLD, SO, TRV, TER, TTEK, VFC, ANTM, WCC, EBAY, DEI, TEL, LULU, AWK, KAR, ST, PRI, FBHS, PRLB, BFAM, IQV, WMS, LBRDA, DVY, IJH, IYH, RWR, XLY,
• Sold Out: SYY, PBCT, G, PNW, PB, ENTG, PENN, ENR, APLE, CMPR, NTCT, MD, FNB, CMP, LGIH, UBSI, DORM, CMD, WAFD, ONB, CIM, DCPH, HE, HCC, UMBF, AIMC, PLT, ARI, UNVR, CATY, TRMK, DUK, TRGP, AME, YELP, MLM, SXI, RE, ARR, TSLA, LOGM, LYV, EFC, DBI, QCOM, KLAC, SSTK, MRVL, REG, GRMN, KEX, LH, VER, APTV, AEP, LVS, CWEN, MTUM, EEMV, OTIS, AAP, BK, CPB, CSFL, FE, TSCO, FLO, GATX, PNFP, PII, RTN, SIRI,

For the details of GREAT LAKES ADVISORS, LLC's stock buys and sells, go to https://www.gurufocus.com/guru/great+lakes+advisors%2C+llc/current-portfolio/portfolio

1. Microsoft Corp (MSFT) - 375,963 shares, 2.07% of the total portfolio. Shares reduced by 1.6%
2. Comcast Corp (CMCSA) - 1,610,502 shares, 1.70% of the total portfolio. Shares added by 29.25%
3. Oracle Corp (ORCL) - 1,094,725 shares, 1.64% of the total portfolio. Shares reduced by 5.31%
4. UnitedHealth Group Inc (UNH) - 200,139 shares, 1.60% of the total portfolio. Shares reduced by 5.25%
5. Berkshire Hathaway Inc (BRK.B) - 292,075 shares, 1.41% of the total portfolio. Shares added by 4.52%

Great Lakes Advisors, Llc initiated holding in RenaissanceRe Holdings Ltd. The purchase prices were between $140.92 and $195.48, with an estimated average price of $164.02. The stock is now traded at around $184.53. The impact to a portfolio due to this purchase was 1.07%. The holding were 230,736 shares as of .

Great Lakes Advisors, Llc initiated holding in Agios Pharmaceuticals Inc. The purchase prices were between $34.45 and $53.48, with an estimated average price of $46.14. The stock is now traded at around $43.40. The impact to a portfolio due to this purchase was 0.47%. The holding were 323,963 shares as of .

Great Lakes Advisors, Llc initiated holding in Zillow Group Inc. The purchase prices were between $30.13 and $63.11, with an estimated average price of $49.4. The stock is now traded at around $71.42. The impact to a portfolio due to this purchase was 0.45%. The holding were 288,259 shares as of .

Great Lakes Advisors, Llc initiated holding in Ameren Corp. The purchase prices were between $67.73 and $79, with an estimated average price of $72.54. The stock is now traded at around $81.06. The impact to a portfolio due to this purchase was 0.44%. The holding were 231,136 shares as of .

Great Lakes Advisors, Llc initiated holding in Inphi Corp. The purchase prices were between $77.68 and $125.67, with an estimated average price of $104.78. The stock is now traded at around $128.50. The impact to a portfolio due to this purchase was 0.38%. The holding were 120,001 shares as of .

Great Lakes Advisors, Llc initiated holding in Cardlytics Inc. The purchase prices were between $29.72 and $81.28, with an estimated average price of $57.39. The stock is now traded at around $67.96. The impact to a portfolio due to this purchase was 0.37%. The holding were 197,392 shares as of .

Great Lakes Advisors, Llc added to a holding in MKS Instruments Inc by 1061.19%. The purchase prices were between $74.98 and $114.61, with an estimated average price of $99.02. The stock is now traded at around $125.76. The impact to a portfolio due to this purchase was 0.41%. The holding were 147,576 shares as of .

Great Lakes Advisors, Llc added to a holding in Comcast Corp by 29.25%. The purchase prices were between $32.42 and $43.12, with an estimated average price of $38.04. The stock is now traded at around $42.87. The impact to a portfolio due to this purchase was 0.38%. The holding were 1,610,502 shares as of .

Great Lakes Advisors, Llc added to a holding in BlackRock Inc by 136.52%. The purchase prices were between $409.54 and $558.06, with an estimated average price of $503.56. The stock is now traded at around $582.23. The impact to a portfolio due to this purchase was 0.33%. The holding were 38,642 shares as of .

Great Lakes Advisors, Llc added to a holding in SL Green Realty Corp by 5003.56%. The purchase prices were between $36.83 and $63.12, with an estimated average price of $47.29. The stock is now traded at around $47.32. The impact to a portfolio due to this purchase was 0.32%. The holding were 246,400 shares as of .

Great Lakes Advisors, Llc added to a holding in The Walt Disney Co by 55.34%. The purchase prices were between $93.88 and $127.28, with an estimated average price of $110.22. The stock is now traded at around $130.82. The impact to a portfolio due to this purchase was 0.25%. The holding were 230,916 shares as of .

Great Lakes Advisors, Llc added to a holding in PNC Financial Services Group Inc by 23.92%. The purchase prices were between $85.19 and $131.13, with an estimated average price of $105.21. The stock is now traded at around $107.03. The impact to a portfolio due to this purchase was 0.23%. The holding were 419,653 shares as of .

Great Lakes Advisors, Llc sold out a holding in Sysco Corp. The sale prices were between $39.5 and $64.11, with an estimated average price of $52.41.

Great Lakes Advisors, Llc sold out a holding in People's United Financial Inc. The sale prices were between $9.51 and $13.79, with an estimated average price of $11.62.

Great Lakes Advisors, Llc sold out a holding in Genpact Ltd. The sale prices were between $26.2 and $38.27, with an estimated average price of $33.67.

Great Lakes Advisors, Llc sold out a holding in Pinnacle West Capital Corp. The sale prices were between $68.19 and $82.23, with an estimated average price of $75.58.

Great Lakes Advisors, Llc sold out a holding in Prosperity Bancshares Inc. The sale prices were between $44.83 and $71.43, with an estimated average price of $57.55.

Great Lakes Advisors, Llc sold out a holding in Entegris Inc. The sale prices were between $41.41 and $64.51, with an estimated average price of $55.34.