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GuruFocus Financial Strength Rank measures how strong a companyย’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength

vs
industry
vs
history
Cash to Debt 3.742
ACRX's Cash to Debt is ranked lower than
59% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 6.36 vs. ACRX: 3.742 )
ACRX' s 10-Year Cash to Debt Range
Min: 1.88   Max: 3.74
Current: 3.74

1.88
3.74
Equity to Asset 0.525
ACRX's Equity to Asset is ranked lower than
91% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 0.52 vs. ACRX: 0.525 )
ACRX' s 10-Year Equity to Asset Range
Min: 0.43   Max: 0.53
Current: 0.53

0.43
0.53
Z-Score: 1.54
GuruFocus Profitability Rank ranks how profitable a company is and how likely the companyย’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
ย•ย•3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rankย•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth

vs
industry
vs
history
Operating margin (%) -1241.10
ACRX's Operating margin (%) is ranked lower than
91% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 8.70 vs. ACRX: -1241.10 )
ACRX' s 10-Year Operating margin (%) Range
Min: -1805.2   Max: -1241.1
Current: -1241.1

-1805.2
-1241.1
Net-margin (%) -1393.6
ACRX's Net-margin (%) is ranked lower than
92% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 6.20 vs. ACRX: -1393.6 )
ACRX' s 10-Year Net-margin (%) Range
Min: -1875.1   Max: -1393.6
Current: -1393.6

-1875.1
-1393.6
ROE (%) -98.6
ACRX's ROE (%) is ranked lower than
90% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 7.20 vs. ACRX: -98.6 )
ACRX' s 10-Year ROE (%) Range
Min: -115.1   Max: -98.6
Current: -98.6

-115.1
-98.6
ROA (%) -51.7
ACRX's ROA (%) is ranked lower than
91% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 4.00 vs. ACRX: -51.7 )
ACRX' s 10-Year ROA (%) Range
Min: -51.7   Max: -49.2
Current: -51.7

-51.7
-49.2
ยป ACRX's 10-Y Financials

Financials


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow

» Details

Guru Trades

ACRX Guru Trades in

ACRX Guru Trades in

Q4 2012

ACRX Guru Trades in Q4 2012

Louis Moore Bacon 150,000 sh (New)
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Q1 2013

ACRX Guru Trades in Q1 2013

Louis Moore Bacon Sold Out
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» Details

Insider Trades

Latest Guru Trades with ACRX



No Insider Trades Found!

Ratios

vs
industry
vs
history
P/B 7.31
ACRX's P/B is ranked lower than
83% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 3.00 vs. ACRX: 7.31 )
ACRX' s 10-Year P/B Range
Min: 2.61   Max: 9.19
Current: 7.31

2.61
9.19
P/S 51.38
ACRX's P/S is ranked lower than
95% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 2.32 vs. ACRX: 51.38 )
ACRX' s 10-Year P/S Range
Min: 31.27   Max: 60.86
Current: 51.38

31.27
60.86
EV-to-EBIT -6.93
ACRX's EV-to-EBIT is ranked higher than
98% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 21.70 vs. ACRX: -6.93 )
ACRX' s 10-Year EV-to-EBIT Range
Min: 4.2   Max: 9.4
Current: -6.93

4.2
9.4

Valuation & Return

vs
industry
vs
history
Price/Net Cash 8.7
ACRX's Price/Net Cash is ranked lower than
54% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 9.70 vs. ACRX: 8.7 )
ACRX' s 10-Year Price/Net Cash Range
Min: 2.7   Max: 3.3
Current: 8.7

2.7
3.3
Price/Net Current Asset Value 186.5
ACRX's Price/Net Current Asset Value is ranked lower than
61% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 10.20 vs. ACRX: 186.5 )
ACRX' s 10-Year Price/Net Current Asset Value Range
Min: 48   Max: 71
Current: 186.5

48
71
Price/Tangible Book 7.4
ACRX's Price/Tangible Book is ranked lower than
61% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 3.40 vs. ACRX: 7.4 )
ACRX' s 10-Year Price/Tangible Book Range
Min: 1.9   Max: 2.8
Current: 7.4

1.9
2.8
Price/Median PS Value 2.4
ACRX's Price/Median PS Value is ranked lower than
57% of the 375 Companies
in the Global Drug Manufacturers - Major industry.

( Industry Median: 0.70 vs. ACRX: 2.4 )
ACRX' s 10-Year Price/Median PS Value Range
Min: 0.9   Max: 0.9
Current: 2.4

Business Description

AcelRx Pharmaceuticals, Inc. was originally incorporated as SuRx, Inc. in Delaware on July 13, 2005. The company subsequently changed its name to AcelRx Pharmaceuticals, Inc. on August 13, 2006. The company is a development stage specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute and breakthrough pain. The company was founded to solve the problems associated with post-operative intravenous patient-controlled analgesia, or IV PCA. Although used, IV PCA has been shown to cause harm to patients following surgery because of the side effects of morphine, the invasive IV route of delivery and the inherent potential for programming and delivery errors associated with the complexity of infusion pumps. In March 2012, it initiated the first of three Phase 3 clinical trials for its lead product candidate, the Sufentanil NanoTab PCA System, or ARX-01 System, or ARX-01. The remaining two Phase 3 studies are expected to start by the third quarter of 2012. The three planned Phase 3 clinical trials include two double-blind, placebo-controlled efficacy and safety trials and one active comparator study. It has completed Phase 2 clinical development for two additional product candidates, the Sufentanil NanoTab BTP Management System, or ARX-02, for the treatment of cancer breakthrough pain, or BTP, and the Sufentanil/Triazolam NanoTab, or ARX-03, designed to provide mild sedation, anxiety reduction and pain relief for patients undergoing painful procedures in a physician's office. In addition, in May 2011, the company announced that the US Army Medical Research and Material Command, or USAMRMC, awarded it a $5.6 million grant to support the development of a new product candidate, the Sufentanil Single-Dose NanoTab for the treatment of moderate-to-severe acute pain, or ARX-04. Under the terms of the grant, the USAMRMC will reimburse it for development, manufacturing and clinical expenses necessary to prepare for and complete the planned Phase 2 dose-finding trial in a study of moderate-to-severe acute pain, and to prepare to enter Phase 3 development. Its strategy is to develop and commercialize a portfolio of sufentanil NanoTab-based products in specialty markets. The company has designed and is developing product candidates that have clearly defined clinical development programs, target commercial market opportunities and require modest commercial organizations in the United States. It competitors include pharmaceutical and biotechnology companies, specialty pharmaceutical and generic drug companies, and medical technology companies.
Company Website
SEC Reports
Industry: Drug Manufacturers - Major
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Traded in other countries:R5X.Germany

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