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GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength : 5/10

vs
industry
vs
history
Cash to Debt 9.67
FOLD's Cash to Debt is ranked lower than
57% of the 964 Companies
in the Global Biotechnology industry.

( Industry Median: 46.43 vs. FOLD: 9.67 )
Ranked among companies with meaningful Cash to Debt only.
FOLD' s Cash to Debt Range Over the Past 10 Years
Min: 3.28  Med: 48.48 Max: No Debt
Current: 9.67
Equity to Asset 0.37
FOLD's Equity to Asset is ranked lower than
80% of the 715 Companies
in the Global Biotechnology industry.

( Industry Median: 0.67 vs. FOLD: 0.37 )
Ranked among companies with meaningful Equity to Asset only.
FOLD' s Equity to Asset Range Over the Past 10 Years
Min: 0.28  Med: 0.49 Max: 0.84
Current: 0.37
0.28
0.84
F-Score: 4
Z-Score: -0.72
M-Score: 5.67
WACC vs ROIC
15.24%
-100.29%
WACC
ROIC
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth : 4/10

vs
industry
vs
history
Operating margin (%) -8362.62
FOLD's Operating margin (%) is ranked lower than
92% of the 749 Companies
in the Global Biotechnology industry.

( Industry Median: -78.20 vs. FOLD: -8362.62 )
Ranked among companies with meaningful Operating margin (%) only.
FOLD' s Operating margin (%) Range Over the Past 10 Years
Min: -17680.72  Med: -1430.62 Max: -11.42
Current: -8362.62
-17680.72
-11.42
Net-margin (%) -8664.36
FOLD's Net-margin (%) is ranked lower than
92% of the 749 Companies
in the Global Biotechnology industry.

( Industry Median: -75.28 vs. FOLD: -8664.36 )
Ranked among companies with meaningful Net-margin (%) only.
FOLD' s Net-margin (%) Range Over the Past 10 Years
Min: -16427.82  Med: -1286.28 Max: -10.2
Current: -8664.36
-16427.82
-10.2
ROE (%) -53.92
FOLD's ROE (%) is ranked lower than
63% of the 878 Companies
in the Global Biotechnology industry.

( Industry Median: -33.45 vs. FOLD: -53.92 )
Ranked among companies with meaningful ROE (%) only.
FOLD' s ROE (%) Range Over the Past 10 Years
Min: -322.07  Med: -82.09 Max: -9.19
Current: -53.92
-322.07
-9.19
ROA (%) -20.07
FOLD's ROA (%) is ranked higher than
58% of the 971 Companies
in the Global Biotechnology industry.

( Industry Median: -29.51 vs. FOLD: -20.07 )
Ranked among companies with meaningful ROA (%) only.
FOLD' s ROA (%) Range Over the Past 10 Years
Min: -104.95  Med: -44.78 Max: -6.13
Current: -20.07
-104.95
-6.13
ROC (Joel Greenblatt) (%) -2327.27
FOLD's ROC (Joel Greenblatt) (%) is ranked lower than
72% of the 931 Companies
in the Global Biotechnology industry.

( Industry Median: -372.06 vs. FOLD: -2327.27 )
Ranked among companies with meaningful ROC (Joel Greenblatt) (%) only.
FOLD' s ROC (Joel Greenblatt) (%) Range Over the Past 10 Years
Min: -2904.44  Med: -1385.29 Max: -134.99
Current: -2327.27
-2904.44
-134.99
Revenue Growth (3Y)(%) -100.00
FOLD's Revenue Growth (3Y)(%) is ranked lower than
97% of the 482 Companies
in the Global Biotechnology industry.

( Industry Median: 4.50 vs. FOLD: -100.00 )
Ranked among companies with meaningful Revenue Growth (3Y)(%) only.
FOLD' s Revenue Growth (3Y)(%) Range Over the Past 10 Years
Min: 0  Med: -70.4 Max: -2.3
Current: -100
EBITDA Growth (3Y)(%) 2.00
FOLD's EBITDA Growth (3Y)(%) is ranked higher than
51% of the 521 Companies
in the Global Biotechnology industry.

( Industry Median: 1.50 vs. FOLD: 2.00 )
Ranked among companies with meaningful EBITDA Growth (3Y)(%) only.
FOLD' s EBITDA Growth (3Y)(%) Range Over the Past 10 Years
Min: -85.6  Med: -13.5 Max: 81.7
Current: 2
-85.6
81.7
EPS Growth (3Y)(%) 3.90
FOLD's EPS Growth (3Y)(%) is ranked higher than
60% of the 511 Companies
in the Global Biotechnology industry.

( Industry Median: -4.20 vs. FOLD: 3.90 )
Ranked among companies with meaningful EPS Growth (3Y)(%) only.
FOLD' s EPS Growth (3Y)(%) Range Over the Past 10 Years
Min: -85.2  Med: -14.2 Max: 54.5
Current: 3.9
-85.2
54.5
» FOLD's 10-Y Financials

Financials (Next Earnings Date: 2017-02-24)


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow
Oprt. Cash Flow & Net Income

» Details

Guru Trades

Q4 2015

FOLD Guru Trades in Q4 2015

RS Investment Management 3,488,863 sh (+21.97%)
Louis Moore Bacon 125,000 sh (unchged)
Paul Tudor Jones Sold Out
Chuck Royce 105,300 sh (-68.47%)
» More
Q1 2016

FOLD Guru Trades in Q1 2016

Paul Tudor Jones 16,950 sh (New)
RS Investment Management 3,527,703 sh (+1.11%)
Chuck Royce Sold Out
Louis Moore Bacon Sold Out
» More
Q2 2016

FOLD Guru Trades in Q2 2016

Paul Tudor Jones 72,981 sh (+330.57%)
RS Investment Management 3,429,187 sh (-2.79%)
» More
Q3 2016

FOLD Guru Trades in Q3 2016

Jim Simons 196,400 sh (New)
Paul Tudor Jones Sold Out
» More
» Details

Insider Trades

Latest Guru Trades with FOLD

(List those with share number changes of more than 20%, or impact to portfolio more than 0.1%)

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Business Description

Industry: Biotechnology » Biotechnology
Compare:NAS:ALDR, NAS:CHRS, NYSE:EBS, OTCPK:MPSYY, NAS:DERM, OTCPK:SXMDF, NAS:ARRY, NAS:AMAG, NAS:RGEN, NAS:OPHT, NAS:INVA, NYSE:AXON, NAS:XNCR, NAS:XLRN, OTCPK:GENSF, NAS:CLVS, NAS:PTLA, OTCPK:PFSCF, NAS:BGNE, NAS:AAAP » details
Traded in other countries:AM6.Germany,
Amicus Therapeutics Inc is a biopharmaceutical company. It is engaged in the discovery, development and commercialization of next-generation medicines for orphan diseases.

Amicus Therapeutics Inc incorporated under the laws of the State of Delaware on February 4, 2002. The Company is a Biopharmaceutical Company focused on the discovery, development and commercialization of next-generation medicines for a range of rare and orphan diseases, with a focus on improved therapies for lysosomal storage disorders (LSDs). IT is focused on developing pharmacological chaperones as monotherapy agents (to be used without ERT) and its Chaperone- Advanced Replacement Therapy, or CHART platform of pharmacological chaperones in combination with ERT. Chaperone- Advanced Replacement Therapy, or CHART, platform has been used to develop our next-generation ERTs by co-formulating therapeutic enzymes with our proprietary pharmacological chaperones. It is also developing migalastat HCl as a monotherapy in two Phase 3 global registration studies ("Study 011" and "Study 012") for Fabry patients with genetic mutations that were amenable to this pharmacological chaperone in a cell-based assay. Study 011 is a 24-month study consisting of a 6-month double-blind, placebo-controlled treatment period (Stage 1); a 6-month open-label follow-up period (Stage 2); and a 12-month open-label extension phase. The Company currently operates in one business segment focusing on the development and commercialization of small molecule, orally administered therapies to treat a range of human genetic diseases. Its competitors include pharmaceutical and biotechnology companies in the U.S. and abroad that have approved therapies or therapies in development for lysosomal storage disorders within core programs. The Company owns certain trademarks in the U.S. and/or abroad, including A AMICUS THERAPEUTICS & design, AMICUS THERAPEUTICS and CHART.

Ratios

vs
industry
vs
history
P/B 2.50
FOLD's P/B is ranked higher than
65% of the 861 Companies
in the Global Biotechnology industry.

( Industry Median: 3.50 vs. FOLD: 2.50 )
Ranked among companies with meaningful P/B only.
FOLD' s P/B Range Over the Past 10 Years
Min: 0.87  Med: 3.26 Max: 14.52
Current: 2.5
0.87
14.52
P/S 390.70
FOLD's P/S is ranked lower than
93% of the 695 Companies
in the Global Biotechnology industry.

( Industry Median: 10.41 vs. FOLD: 390.70 )
Ranked among companies with meaningful P/S only.
FOLD' s P/S Range Over the Past 10 Years
Min: 0.84  Med: 24.46 Max: 4540
Current: 390.7
0.84
4540
Current Ratio 2.59
FOLD's Current Ratio is ranked lower than
67% of the 957 Companies
in the Global Biotechnology industry.

( Industry Median: 4.22 vs. FOLD: 2.59 )
Ranked among companies with meaningful Current Ratio only.
FOLD' s Current Ratio Range Over the Past 10 Years
Min: 2.59  Med: 7.48 Max: 21.6
Current: 2.59
2.59
21.6
Quick Ratio 2.55
FOLD's Quick Ratio is ranked lower than
64% of the 957 Companies
in the Global Biotechnology industry.

( Industry Median: 3.94 vs. FOLD: 2.55 )
Ranked among companies with meaningful Quick Ratio only.
FOLD' s Quick Ratio Range Over the Past 10 Years
Min: 2.55  Med: 7.48 Max: 21.6
Current: 2.55
2.55
21.6
Days Inventory 731.06
FOLD's Days Inventory is ranked lower than
98% of the 448 Companies
in the Global Biotechnology industry.

( Industry Median: 128.70 vs. FOLD: 731.06 )
Ranked among companies with meaningful Days Inventory only.
FOLD' s Days Inventory Range Over the Past 10 Years
Min: 0  Med: 0 Max: 731.06
Current: 731.06
0
731.06
Days Sales Outstanding 148.27
FOLD's Days Sales Outstanding is ranked lower than
84% of the 601 Companies
in the Global Biotechnology industry.

( Industry Median: 61.72 vs. FOLD: 148.27 )
Ranked among companies with meaningful Days Sales Outstanding only.
FOLD' s Days Sales Outstanding Range Over the Past 10 Years
Min: 63.94  Med: 85.88 Max: 1088.97
Current: 148.27
63.94
1088.97

Buy Back

vs
industry
vs
history
3-Year Average Share Buyback Ratio -36.10
FOLD's 3-Year Average Share Buyback Ratio is ranked lower than
80% of the 555 Companies
in the Global Biotechnology industry.

( Industry Median: -11.30 vs. FOLD: -36.10 )
Ranked among companies with meaningful 3-Year Average Share Buyback Ratio only.
FOLD' s 3-Year Average Share Buyback Ratio Range Over the Past 10 Years
Min: -317.5  Med: -36.1 Max: -15.3
Current: -36.1
-317.5
-15.3

Valuation & Return

vs
industry
vs
history
Price/Median PS Value 15.84
FOLD's Price/Median PS Value is ranked lower than
98% of the 589 Companies
in the Global Biotechnology industry.

( Industry Median: 0.93 vs. FOLD: 15.84 )
Ranked among companies with meaningful Price/Median PS Value only.
FOLD' s Price/Median PS Value Range Over the Past 10 Years
Min: 0.04  Med: 0.69 Max: 141.5
Current: 15.84
0.04
141.5
Earnings Yield (Greenblatt) (%) -28.02
FOLD's Earnings Yield (Greenblatt) (%) is ranked lower than
77% of the 942 Companies
in the Global Biotechnology industry.

( Industry Median: -8.50 vs. FOLD: -28.02 )
Ranked among companies with meaningful Earnings Yield (Greenblatt) (%) only.
FOLD' s Earnings Yield (Greenblatt) (%) Range Over the Past 10 Years
Min: -28.4  Med: 98.9 Max: 913.7
Current: -28.02
-28.4
913.7

More Statistics

Revenue (TTM) (Mil) $2.13
EPS (TTM) $ -1.43
Beta1.76
Short Percentage of Float30.91%
52-Week Range $4.98 - 10.54
Shares Outstanding (Mil)142.33

Analyst Estimate

Dec16
Revenue (Mil $)
EPS ($) -0.76
EPS w/o NRI ($) -0.76
EPS Growth Rate
(3Y to 5Y Estimate)
N/A
Dividends Per Share ($)
» More Articles for FOLD

Headlines

Articles On GuruFocus.com
Weekly CEO Sells Highlight: Globus Medical Inc, Diplomat Pharmacy Inc, Zendesk Inc, and Amicus Thera Mar 28 2015 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) Nov 09 2010 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) Aug 06 2010 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) May 07 2010 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) Nov 04 2009 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) Aug 06 2009 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) May 08 2009 

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