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GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength : 5/10

vs
industry
vs
history
Cash to Debt 5.96
FOLD's Cash to Debt is ranked higher than
66% of the 1239 Companies
in the Global Biotechnology industry.

( Industry Median: 60.65 vs. FOLD: 5.96 )
FOLD' s 10-Year Cash to Debt Range
Min: 4.97   Max: No Debt
Current: 5.96

Equity to Asset 0.35
FOLD's Equity to Asset is ranked higher than
56% of the 922 Companies
in the Global Biotechnology industry.

( Industry Median: 0.67 vs. FOLD: 0.35 )
FOLD' s 10-Year Equity to Asset Range
Min: 0.28   Max: 0.84
Current: 0.35

0.28
0.84
F-Score: 2
Z-Score: -1.65
M-Score: 47.78
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth : 1/10

vs
industry
vs
history
Operating margin (%) -4037.02
FOLD's Operating margin (%) is ranked higher than
53% of the 1013 Companies
in the Global Biotechnology industry.

( Industry Median: -78.59 vs. FOLD: -4037.02 )
FOLD' s 10-Year Operating margin (%) Range
Min: -17680.72   Max: -11.42
Current: -4037.02

-17680.72
-11.42
Net-margin (%) -3872.29
FOLD's Net-margin (%) is ranked higher than
53% of the 1013 Companies
in the Global Biotechnology industry.

( Industry Median: -70.38 vs. FOLD: -3872.29 )
FOLD' s 10-Year Net-margin (%) Range
Min: -16427.82   Max: -10.2
Current: -3872.29

-16427.82
-10.2
ROE (%) -163.86
FOLD's ROE (%) is ranked higher than
54% of the 1134 Companies
in the Global Biotechnology industry.

( Industry Median: -34.93 vs. FOLD: -163.86 )
FOLD' s 10-Year ROE (%) Range
Min: -319.35   Max: -9.19
Current: -163.86

-319.35
-9.19
ROA (%) -54.25
FOLD's ROA (%) is ranked higher than
62% of the 1239 Companies
in the Global Biotechnology industry.

( Industry Median: -28.51 vs. FOLD: -54.25 )
FOLD' s 10-Year ROA (%) Range
Min: -3515.77   Max: -6.13
Current: -54.25

-3515.77
-6.13
ROC (Joel Greenblatt) (%) -1662.31
FOLD's ROC (Joel Greenblatt) (%) is ranked higher than
64% of the 1212 Companies
in the Global Biotechnology industry.

( Industry Median: -442.83 vs. FOLD: -1662.31 )
FOLD' s 10-Year ROC (Joel Greenblatt) (%) Range
Min: -2018.52   Max: -157.76
Current: -1662.31

-2018.52
-157.76
Revenue Growth (%) -30.70
FOLD's Revenue Growth (%) is ranked higher than
64% of the 717 Companies
in the Global Biotechnology industry.

( Industry Median: -1.90 vs. FOLD: -30.70 )
FOLD' s 10-Year Revenue Growth (%) Range
Min: 0   Max: -2.6
Current: -30.7

EBITDA Growth (%) -14.80
FOLD's EBITDA Growth (%) is ranked higher than
69% of the 707 Companies
in the Global Biotechnology industry.

( Industry Median: -4.60 vs. FOLD: -14.80 )
FOLD' s 10-Year EBITDA Growth (%) Range
Min: 0   Max: 82.8
Current: -14.8

0
82.8
EPS Growth (%) -16.30
FOLD's EPS Growth (%) is ranked higher than
70% of the 723 Companies
in the Global Biotechnology industry.

( Industry Median: -7.40 vs. FOLD: -16.30 )
FOLD' s 10-Year EPS Growth (%) Range
Min: -85.2   Max: 59.5
Current: -16.3

-85.2
59.5
» FOLD's 10-Y Financials

Financials


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow

» Details

Guru Trades

Q4 2013

FOLD Guru Trades in Q4 2013

Jim Simons 399,401 sh (+31.99%)
RS Investment Management 2,797,339 sh (+0.1%)
Chuck Royce 355,700 sh (-31.03%)
» More
Q1 2014

FOLD Guru Trades in Q1 2014

Charles Brandes 48,100 sh (New)
RS Investment Management 2,816,739 sh (+0.69%)
Chuck Royce 313,700 sh (-11.81%)
Jim Simons 121,000 sh (-69.7%)
» More
Q2 2014

FOLD Guru Trades in Q2 2014

George Soros 70,500 sh (New)
Jim Simons Sold Out
Charles Brandes Sold Out
RS Investment Management Sold Out
Chuck Royce 283,700 sh (-9.56%)
» More
Q3 2014

FOLD Guru Trades in Q3 2014

Charles Brandes 36,700 sh (New)
Jim Simons 130,400 sh (New)
RS Investment Management 1,248,215 sh (New)
Paul Tudor Jones 78,079 sh (New)
Steven Cohen 195,900 sh (New)
Chuck Royce Sold Out
George Soros Sold Out
» More
» Details

Insider Trades

Latest Guru Trades with FOLD

(List those with share number changes of more than 20%, or impact to portfolio more than 0.1%)

GuruDate Trades Impact to Portfolio Price Range * (?) Current Price Change from Average Current Shares
George Soros 2014-09-30 Sold Out $3.6 - $7.47 $ 6.9732%0
Charles Brandes 2014-09-30 New Buy$3.6 - $7.47 $ 6.9732%36700
George Soros 2014-06-30 New Buy$1.82 - $3.03 $ 6.97199%70500
Charles Brandes 2014-06-30 Sold Out $1.82 - $3.03 $ 6.97199%0
Charles Brandes 2014-03-31 New Buy$2.04 - $3.08 $ 6.97179%48100
Premium More recent guru trades are included for Premium Members only!!
Premium More recent guru trades are included for USA Subscribe Members only!!
» Interactive Charts

Peter Lynch Chart ( What is Peter Lynch Charts )

Ratios

vs
industry
vs
history
P/B 12.67
FOLD's P/B is ranked higher than
63% of the 1323 Companies
in the Global Biotechnology industry.

( Industry Median: 5.76 vs. FOLD: 12.67 )
FOLD' s 10-Year P/B Range
Min: 0.64   Max: 14.38
Current: 12.67

0.64
14.38
EV-to-EBIT -7.71
FOLD's EV-to-EBIT is ranked higher than
83% of the 1323 Companies
in the Global Biotechnology industry.

( Industry Median: 9999.00 vs. FOLD: -7.71 )
FOLD' s 10-Year EV-to-EBIT Range
Min: -6.9   Max: 3.9
Current: -7.71

-6.9
3.9
Current Ratio 6.31
FOLD's Current Ratio is ranked higher than
79% of the 1228 Companies
in the Global Biotechnology industry.

( Industry Median: 4.73 vs. FOLD: 6.31 )
FOLD' s 10-Year Current Ratio Range
Min: 3.46   Max: 18.26
Current: 6.31

3.46
18.26
Quick Ratio 6.31
FOLD's Quick Ratio is ranked higher than
80% of the 1228 Companies
in the Global Biotechnology industry.

( Industry Median: 4.53 vs. FOLD: 6.31 )
FOLD' s 10-Year Quick Ratio Range
Min: 3.46   Max: 18.26
Current: 6.31

3.46
18.26

Valuation & Return

vs
industry
vs
history
Price/Net Cash 174.25
FOLD's Price/Net Cash is ranked higher than
72% of the 1323 Companies
in the Global Biotechnology industry.

( Industry Median: 64.50 vs. FOLD: 174.25 )
FOLD' s 10-Year Price/Net Cash Range
Min: 1.06   Max: 152.25
Current: 174.25

1.06
152.25
Price/Net Current Asset Value 174.25
FOLD's Price/Net Current Asset Value is ranked higher than
70% of the 1323 Companies
in the Global Biotechnology industry.

( Industry Median: 34.97 vs. FOLD: 174.25 )
FOLD' s 10-Year Price/Net Current Asset Value Range
Min: 1.06   Max: 235
Current: 174.25

1.06
235
Price/Tangible Book 63.36
FOLD's Price/Tangible Book is ranked higher than
62% of the 1323 Companies
in the Global Biotechnology industry.

( Industry Median: 9.12 vs. FOLD: 63.36 )
FOLD' s 10-Year Price/Tangible Book Range
Min: 0.96   Max: 55.36
Current: 63.36

0.96
55.36
Earnings Yield (Greenblatt) -13.00
FOLD's Earnings Yield (Greenblatt) is ranked higher than
64% of the 1174 Companies
in the Global Biotechnology industry.

( Industry Median: -6.40 vs. FOLD: -13.00 )
FOLD' s 10-Year Earnings Yield (Greenblatt) Range
Min: 25.7   Max: 5589.6
Current: -13

25.7
5589.6
Forward Rate of Return (Yacktman) -11.31
FOLD's Forward Rate of Return (Yacktman) is ranked higher than
72% of the 832 Companies
in the Global Biotechnology industry.

( Industry Median: -6.41 vs. FOLD: -11.31 )
FOLD' s 10-Year Forward Rate of Return (Yacktman) Range
Min: -1148.1   Max: -13.5
Current: -11.31

-1148.1
-13.5

Business Description

Industry: Biotechnology » Biotechnology
Compare:NVO, AMGN, GILD, BIIB, CELG » details
Traded in other countries:AM6.Germany
Amicus Therapeutics Inc incorporated under the laws of the State of Delaware on February 4, 2002. The Company is a Biopharmaceutical Company focused on the discovery, development and commercialization of next-generation medicines for a range of rare and orphan diseases, with a focus on improved therapies for lysosomal storage disorders (LSDs). IT is focused on developing pharmacological chaperones as monotherapy agents (to be used without ERT) and its Chaperone-Advanced Replacement Therapy, or CHART platform of pharmacological chaperones in combination with ERT. Chaperone-Advanced Replacement Therapy, or CHART, platform has been used to develop our next-generation ERTs by co-formulating therapeutic enzymes with our proprietary pharmacological chaperones. It is also developing migalastat HCl as a monotherapy in two Phase 3 global registration studies ("Study 011" and "Study 012") for Fabry patients with genetic mutations that were amenable to this pharmacological chaperone in a cell-based assay. Study 011 is a 24-month study consisting of a 6-month double-blind, placebo-controlled treatment period (Stage 1); a 6-month open-label follow-up period (Stage 2); and a 12-month open-label extension phase. The Company currently operates in one business segment focusing on the development and commercialization of small molecule, orally administered therapies to treat a range of human genetic diseases. Its major competitors include pharmaceutical and biotechnology companies in the U.S. and abroad that have approved therapies or therapies in development for lysosomal storage disorders within our core programs. The Company owns certain trademarks in the U.S. and/or abroad, including A AMICUS THERAPEUTICS & design, AMICUS THERAPEUTICS and CHART.
» More Articles for FOLD

Headlines

Articles On GuruFocus.com
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) Nov 09 2010 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) Aug 06 2010 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) May 07 2010 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) Nov 04 2009 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) Aug 06 2009 
AMICUS THERAPEUTICS, INC. Reports Operating Results (10-Q) May 08 2009 
iwillbeback note on FOLD Sep 03 2008 

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