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Also traded in: Germany, Israel, Mexico

GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength : 7/10

vs
industry
vs
history
Cash-to-Debt 1.61
OPK's Cash-to-Debt is ranked lower than
58% of the 799 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 3.09 vs. OPK: 1.61 )
Ranked among companies with meaningful Cash-to-Debt only.
OPK' s Cash-to-Debt Range Over the Past 10 Years
Min: 0.48  Med: 20.9 Max: No Debt
Current: 1.61
Equity-to-Asset 0.76
OPK's Equity-to-Asset is ranked higher than
71% of the 734 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 0.64 vs. OPK: 0.76 )
Ranked among companies with meaningful Equity-to-Asset only.
OPK' s Equity-to-Asset Range Over the Past 10 Years
Min: 0.02  Med: 0.66 Max: 0.96
Current: 0.76
0.02
0.96
Piotroski F-Score: 6
Altman Z-Score: 3.95
Beneish M-Score: -1.76
WACC vs ROIC
16.38%
-0.86%
WACC
ROIC
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth : 6/10

vs
industry
vs
history
Operating Margin % -6.00
OPK's Operating Margin % is ranked lower than
77% of the 744 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 8.42 vs. OPK: -6.00 )
Ranked among companies with meaningful Operating Margin % only.
OPK' s Operating Margin % Range Over the Past 10 Years
Min: -31624.44  Med: -82.69 Max: -6
Current: -6
-31624.44
-6
Net Margin % -2.05
OPK's Net Margin % is ranked lower than
74% of the 745 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 6.16 vs. OPK: -2.05 )
Ranked among companies with meaningful Net Margin % only.
OPK' s Net Margin % Range Over the Past 10 Years
Min: -31688.9  Med: -92.47 Max: -2.05
Current: -2.05
-31688.9
-2.05
ROE % -1.23
OPK's ROE % is ranked lower than
71% of the 768 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 6.86 vs. OPK: -1.23 )
Ranked among companies with meaningful ROE % only.
OPK' s ROE % Range Over the Past 10 Years
Min: -3196.93  Med: -20.87 Max: -1.23
Current: -1.23
-3196.93
-1.23
ROA % -0.90
OPK's ROA % is ranked lower than
69% of the 799 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 3.49 vs. OPK: -0.90 )
Ranked among companies with meaningful ROA % only.
OPK' s ROA % Range Over the Past 10 Years
Min: -1352.71  Med: -13.26 Max: -0.83
Current: -0.9
-1352.71
-0.83
ROC (Joel Greenblatt) % -35.32
OPK's ROC (Joel Greenblatt) % is ranked lower than
78% of the 785 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 13.40 vs. OPK: -35.32 )
Ranked among companies with meaningful ROC (Joel Greenblatt) % only.
OPK' s ROC (Joel Greenblatt) % Range Over the Past 10 Years
Min: -130662.93  Med: -258.52 Max: -35.32
Current: -35.32
-130662.93
-35.32
3-Year Revenue Growth Rate 101.30
OPK's 3-Year Revenue Growth Rate is ranked higher than
98% of the 607 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 5.70 vs. OPK: 101.30 )
Ranked among companies with meaningful 3-Year Revenue Growth Rate only.
OPK' s 3-Year Revenue Growth Rate Range Over the Past 10 Years
Min: 0  Med: 26 Max: 152
Current: 101.3
0
152
3-Year EPS without NRI Growth Rate -46.30
OPK's 3-Year EPS without NRI Growth Rate is ranked lower than
95% of the 551 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 7.00 vs. OPK: -46.30 )
Ranked among companies with meaningful 3-Year EPS without NRI Growth Rate only.
OPK' s 3-Year EPS without NRI Growth Rate Range Over the Past 10 Years
Min: -69.4  Med: -9.3 Max: 152.4
Current: -46.3
-69.4
152.4
GuruFocus has detected 1 Warning Sign with OPKO Health Inc $OPK.
More than 500,000 people have already joined GuruFocus to track the stocks they follow and exchange investment ideas.
» OPK's 10-Y Financials

Financials (Next Earnings Date: 2017-05-28 Est.)


Revenue & Net Income
Cash & Debt
Operating Cash Flow & Free Cash Flow
Operating Cash Flow & Net Income

» Details

Guru Trades

Q2 2016

OPK Guru Trades in Q2 2016

Paul Tudor Jones 27,173 sh (New)
Joel Greenblatt 267,485 sh (+786.33%)
Ken Fisher 37,826 sh (-0.11%)
Murray Stahl 66,333 sh (-1.30%)
Mario Gabelli 97,050 sh (-3.70%)
» More
Q3 2016

OPK Guru Trades in Q3 2016

Jim Simons 1,412,757 sh (New)
George Soros 59,837 sh (New)
John Burbank 12,234 sh (New)
Joel Greenblatt 535,214 sh (+100.09%)
Paul Tudor Jones 36,248 sh (+33.40%)
Ken Fisher 38,229 sh (+1.07%)
Mario Gabelli 97,050 sh (unchged)
Murray Stahl 60,179 sh (-9.28%)
» More
Q4 2016

OPK Guru Trades in Q4 2016

Ken Fisher 39,229 sh (+2.62%)
Jim Simons Sold Out
John Burbank Sold Out
George Soros Sold Out
Paul Tudor Jones Sold Out
Mario Gabelli 94,550 sh (-2.58%)
Murray Stahl 58,149 sh (-3.37%)
Joel Greenblatt 167,109 sh (-68.78%)
» More
Q1 2017

OPK Guru Trades in Q1 2017

Ken Fisher 38,979 sh (-0.64%)
» More
» Details

Insider Trades

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Business Description

Industry: Drug Manufacturers » Drug Manufacturers - Specialty & Generic    NAICS: 325412    SIC: 2834
Compare:OTCPK:STDAF, NAS:AKRX, OTCPK:GEDSF, NYSE:PTHN, NYSE:TARO, NYSE:MNK, NYSE:CTLT, NAS:MDCO, NYSE:VRX, OTCPK:IZQVF, OTCPK:HYPMY, OTCPK:HKMPF, NAS:ENDP, NAS:HZNP, NAS:IRWD, OTCPK:MDABY, OTCPK:SWPIF, NAS:PCRX, NYSE:RDY, NAS:RDUS » details
Traded in other countries:XCY.Germany, OPK.Israel, OPK.Mexico,
Headquarter Location:USA
OPKO Health Inc is a diversified healthcare company. The Company's operating business segments are diagnostics and pharmaceutical.

Opko Health is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Opko's diagnostics business includes a core genetic testing operation. It has a development and commercial supply pharmaceutical company, as well as a global supply-chain operation and holding company in Ireland. Opko also owns a specialty active pharmaceutical ingredients manufacturer in Israel. The company's bio-reference testing business consists of routine testing and esoteric testing. Routine tests measure various health parameters, such as the functions of the heart, kidney, liver, thyroid, and other organs.

Top Ranked Articles about OPKO Health Inc

Weekly CEO Buys Highlights Insiders invest in Wells Fargo, OPKO, Texas Capital, PacWest and Guess?
According to GuruFocus’ Insider Data, these are the largest CEO buys during the past week. The overall trend of purchases is illustrated in the chart below: Read more...
Insiders Roundup: NuStar Energy, Opko Health, Alphabet Largest insider buys and sales of the week
The GuruFocus All-in-One Screener can be used to find insider trades from the past week. Under the Insiders tab, change the settings for All Insider Buying to “$200,000+,” the duration to “April 2017” and All Insider Sales to “$5,000,000+.” Read more...
Weekly CEO Buys Highlights Insiders purchase shares of G-III Apparel, OPKO and Washington Prime
According to GuruFocus’ Insider Data, these are the largest CEO buys during the past week. The overall trend of purchases is illustrated in the chart below: Read more...
ChromaDex Appoints Steven D. Rubin, J.D., to its Board of Directors

IRVINE, Calif., March 28, 2017 (GLOBE NEWSWIRE) -- ChromaDex Corp. (NASDAQ:CDXC), an innovator of proprietary health, wellness and nutritional ingredients that creates science-based solutions for dietary supplement, food and beverage, skin care, sports nutrition, and pharmaceutical products, announced today that Steven D. Rubin, J.D. has joined the Company’s board of directors. Mr. Rubin, age 56, has served as OPKO Health, Inc.’s (NASDAQ:OPK) Executive Vice President – Administration since May 2007 and as a director of since February 2007. Mr. Rubin is a member of The Frost Group, LLC, a private investment firm. He has extensive experience as a practicing lawyer, and as general counsel and board member to multiple public companies. Mr. Rubin currently serves on the board of directors for the following companies: VBI Vaccines Inc., a commercial-stage biopharmaceutical company developing a next generation of vaccines; Cognit, Inc., a data and analytics company providing cloud-based mission-critical information and performance marketing solutions; Kidville, Inc., an operator of large, upscale facilities, catering to newborns through five-year-old children and their families and offers a wide range of developmental classes for newborns to five-year-olds; Non-Invasive Monitoring Systems, Inc., a medical device company; BioCardia, Inc., a clinical-stage regenerative medicine company developing novel therapeutics for cardiovascular diseases; Cocrystal Pharma, Inc., a biotechnology company developing new treatments for viral diseases; Sevion Therapeutics, Inc., a clinical stage company which discovers and develops next-generation biologics for the treatment of cancer and immunological diseases; Castle Brands, Inc., a developer and marketer of premium brand spirits; and, Neovasc, Inc., a company developing and marketing medical specialty vascular devices. Mr. Rubin previously served as the Senior Vice President, General Counsel and Secretary of IVAX from August 2001 until September 2006. Mr. Rubin previously served as a director of the following companies: Dreams, Inc. ( MKT:DRJ), a vertically integrated sports licensing and products company; Safestitch Medical, Inc. prior to its merger with TransEnterix, Inc.; and, PROLOR Biotech, Inc., prior to its acquisition by the Company in August 2013. About ChromaDex:
ChromaDex leverages its complementary business units to discover, acquire, develop and commercialize patented and proprietary ingredient technologies that address the dietary supplement, food, beverage, skin care and pharmaceutical markets. In addition to our ingredient technologies unit, we also have business units focused on natural product fine chemicals (known as "phytochemicals"), chemistry and analytical testing services, and product regulatory and safety consulting. As a result of our relationships with leading universities and research institutions, we are able to discover and license early stage, IP-backed ingredient technologies. We then utilize our in-house chemistry, regulatory and safety consulting business units to develop commercially viable ingredients. Our ingredient portfolio is backed with clinical and scientific research, as well as extensive IP protection. Our portfolio of patented ingredient technologies includes NIAGEN® nicotinamide riboside; pTeroPure® pterostilbene; PURENERGY®, a caffeine-pTeroPure® co-crystal; IMMULINA™, a spirulina extract; and AnthOrigin™, anthocyanins derived from a domestically-produced, water-extracted purple corn. To learn more about ChromaDex, please visit www.ChromaDex.com. Forward-Looking Statements: This release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities and Exchange Act of 1934, as amended, including statements related to the composition and experience of ChromaDex’s board of directors. Statements that are not a description of historical facts constitute forward-looking statements and may often, but not always, be identified by the use of such words as "expects", "anticipates", "intends", "estimates", "plans", "potential", "possible", "probable", "believes", "seeks", "may", "will", "should", "could" or the negative of such terms or other similar expressions. More detailed information about ChromaDex and the risk factors that may affect the realization of forward-looking statements is set forth in ChromaDex's Annual Report on Form 10-K for the fiscal year ended December 31, 2016, ChromaDex's Quarterly Reports on Form 10-Q and other filings submitted by ChromaDex to the SEC, copies of which may be obtained from the SEC's website at www.sec.gov. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and actual results may differ materially from those suggested by these forward-looking statements. All forward-looking statements are qualified in their entirety by this cautionary statement and ChromaDex undertakes no obligation to revise or update this release to reflect events or circumstances after the date hereof.
ChromaDex Investor Relations Contact:
Andrew Johnson, Director of Investor Relations
949-419-0288
[email protected]

ChromaDex Public Relations Contact:
Breah Ostendorf, Director of Marketing
949-537-4103
[email protected]

Read more...
OPKO Receives FDA Orphan Drug Status for its New Oligonucleotide to Treat Genetic Neurological Disorder

MIAMI, March 22, 2017 (GLOBE NEWSWIRE) -- OPKO Pharmaceuticals LLC, a subsidiary of OPKO Health, Inc. (NASDAQ:OPK) announces that the Company has received orphan drug designation from the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development for OPKO’s oligonucleotide-based AntagoNAT (CUR-1916) for the treatment of Dravet Syndrome.  Currently, there is no approved treatment for Dravet Syndrome in the U.S.  On March 7, 2017, OPKO Health received orphan drug designation for CUR-1916 for the treatment of Dravet Syndrome from the European Commission.
Orphan drug designation provides certain marketing exclusivity, tax credits for research and a waiver of the New Drug Application user fee.  AntagoNAT, anti-Natural Antisense Transcripts, is an OPKO platform technology in which single strand oligonucleotide molecules are designed to interfere with regulatory gene expression in order to enhance production of endogenous functional proteins.  The AntagoNAT technology, part of CURNA Pharmaceuticals, acquired by OPKO in 2011, was further developed in OPKO’s Miami research laboratories under the direction of Jane Hsiao, Ph.D., OPKO’s Vice Chairman and Chief Technical Officer. OPKO has studied over 250 genes and confirmed involvement of natural antisense transcripts (NAT) in their regulatory pathways. Of those, 89 genes were demonstrated to be subject to significant upregulation of mRNA in in vitro screening, and seven AntagoNAT oligonucleotides have been validated in vivo to date. OPKO plans to initiate a clinical trial of CUR-1916 for treatment of Dravet Syndrome this year. Oligonucleotides are synthetic chemical compounds consisting of mixtures of modified DNAs and RNAs. Only five oligonucleotide compounds are approved by FDA for various indications and others have been reported to be in late phase clinical development. The majority of the compounds work by down regulating, or depressing transcription (anti-sense) or by correcting gene defects. CUR-1916 works by upregulating a defective gene to increase the production of functional protein. About FDA Orphan Drug Designation Under the Orphan Drug Act (ODA) the FDA grants Orphan Drug status to drugs, vaccines, and diagnostic agents intended to treat a disease affecting less than 200,000 American citizens. Under the ODA, orphan drug sponsors qualify for seven-year FDA administered market Orphan Drug Exclusivity, tax credits of up to 50% of R&D costs, R&D grants, waived FDA fees, protocol assistance and may get clinical trial tax incentives. What is Dravet Syndrome? Dravet Syndrome, also called severe myoclonic epilepsy of infancy (SMEI), is a severe form of epilepsy that affects children and adults. It is caused by defects in the SCN1A genes (voltage gated sodium channel) required for the proper function of brain cells. In Dravet Syndrome, seizures begin in the first year of life, and are most often associated with elevated body temperature (febrile convulsions). Later, other types of seizures occur, including status epilepticus (seizures lasting at least 5 minutes and requiring emergency medical care). From age 2, the child’s development begins to decline or reverse, and results in impaired mental and motor skills, leading to long term disability. Dravet Syndrome also qualifies as a Rare Pediatric Disease under Section 529 of Food, Drug, and Cosmetic Act (the FD&C Act). Dravet Syndrome is debilitating and the death rate is reported to be 10-15%. About OPKO Health OPKO Health is a diversified healthcare company that seeks to establish industry leading positions in large, rapidly growing markets. Our diagnostics business includes BioReference Laboratories, the nation’s third largest clinical laboratory with a core genetic testing business and a 400 person sales and marketing team to drive growth and leverage new products, including the 4Kscore® prostate cancer test and the Claros® 1 in office immunoassay platform. Our pharmaceutical business features RAYALDEE, an FDA approved treatment for SHPT in stage 3-4 CKD patients with vitamin D insufficiency (launched in November 2016), VARUBI™ for chemotherapy induced nausea and vomiting (oral formulation launched by partner TESARO and IV formulation pending FDA approval), TT401, a once or twice weekly oxyntomodulin for type 2 diabetes and obesity, in  phase 2 clinical trials, among  the new class of GLP-1 glucagon receptor dual agonists, and TT701, a selective  androgen receptor modulator  for benign prostatic hyperplasia  (phase 2). Our biologics business includes hGH-CTP, a once weekly human growth hormone in phase 3 and partnered with Pfizer; and a long-acting Factor VIIa drug for hemophilia in phase 2a.   More information available at www.opko.com Cautionary Statement Regarding Forward-Looking Statements This press release contains "forward-looking statements," as that term is defined under the Private Securities Litigation Reform Act of 1995 (PSLRA), which statements may be identified by words such as "expects," "plans," "projects," "will," "may," "anticipates," "believes," "should," "intends," "estimates," and other words of similar meaning, including statements regarding expectations about CUR-1916 and its effectiveness in treating Dravet syndrome, whether the drug will receive orphan designation in the U.S., whether we will commence clinical trials for CUR-1916 this year or at all,  whether the data from any of our trials will support approval, validation and/or reimbursement for our products,  as well as other non-historical statements about our expectations, beliefs or intentions regarding our business, technologies and products, financial condition, strategies or prospects. Many factors could cause our actual activities or results to differ materially from the activities and results anticipated in forward-looking statements. These factors include those described in our Annual Reports on Form 10-K filed and to be filed with the Securities and Exchange Commission and in our other filings with the Securities and Exchange Commission, as well as the risks inherent in funding, developing and obtaining regulatory approvals of new, commercially-viable and competitive products and treatments. The forward-looking statements contained in this press release speak only as of the date the statements were made, and we do not undertake any obligation to update forward-looking statements. We intend that all forward-looking statements be subject to the safe-harbor provisions of the PSLRA. Company
OPKO Health, Inc.
David Malina, 305-575-4100

Investor Relations
or
Media
Rooney Partners
Terry Rooney, 212-223-0689
[email protected]
or
Marion Janic, 212-223-4017
[email protected]
or
Investors
LHA
Anne Marie Fields, 212-838-3777
[email protected]
or
Bruce Voss, 310-691-7100
[email protected] 


Read more...
OPKO Health's GeneDx to have Significant Presence at ACMG 2017

Launching New Genetic Tests in Multiple Indications
Multiple Poster and Platform Presentations Highlight GeneDx’ Broad Offerings in a Variety of Genetic Specialties MIAMI, March 14, 2017 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ:OPK)   announces that GeneDx, a subsidiary of OPKO Health, will have a prominent presence at  the American College of Medical Genetics and Genomics (ACMG) Annual Meeting taking place from March 21-24, 2017 in Phoenix, Arizona. GeneDx has been selected to present research data in 14 poster presentations and four platform presentations. The platform presentations will cover the utilization of exome sequencing in the context of abnormal ultrasound findings, ataxia-related neurologic disorders, immunological conditions, and for testing the contribution of genetic mosaicism to Mendelian disorders. The platform presentations can be accessed here.  The poster presentations will cover a variety of topics including hereditary cancers, epilepsy, autism/intellectual disability, and whole exome sequencing and can be accessed here. GeneDx also announces the launch of several new tests to expand testing flexibility for multiple indications.  GeneDx will be offering new or expanded tests for ataxia-related disorders, autism and intellectual disability, neuropathy and epilepsy. GeneDx has sequenced more than 55,000 clinical exomes to date.  To further expand this clinical genomics program, whole genome sequencing will be offered to clinicians and research programs to help patients who may benefit from this test. These exome sequencing options will soon be launched and are intended for healthy individuals or couples who would like to have these tests because of family history concerns, fertility or pregnancy related outcomes, or the desire to know more about their genetic health. These tests will require an order by a qualified healthcare provider with appropriate genetic counseling. “We are thrilled to have such an outstanding presence at the annual ACMG conference this year as it provides us an opportunity to showcase our growing genetic testing offering to an audience of key genetics and genomics specialists. Having 18 abstracts accepted by ACMG reflects our ongoing mission of commitment to research and collaboration,” said Ben Solomon, MD, FACMG, Managing Director of GeneDx. “We also welcome the opportunity to speak directly to the genetics community about the expansion of our truly unmatched testing menu.” If attending ACMG, visit GeneDx at booth #401 to learn more. About the American College of Medical Genetics and Genomics
Founded in 1991, the American College of Medical Genetics and Genomics advances the practice of medical genetics and genomics by providing education, resources and a voice for more than 1600 biochemical, clinical, cytogenetic, medical and molecular geneticists, genetic counselors and other healthcare professionals committed to the practice of medical genetics. ACMG’s activities include the development of laboratory and practice standards and guidelines, advocating for quality genetic services in healthcare and in public health, and promoting the development of methods to diagnose, treat and prevent genetic disease. Genetics In Medicine, published monthly, is the official ACMG peer-reviewed journal. ACMG’s website (www.acmg.net) offers a variety of resources including Policy Statements, Practice Guidelines, Educational Resources, and a Find a Geneticist tool. About GeneDx
GeneDx is a world leader in genomics with an acknowledged expertise in rare and ultra-rare genetic disorders, as well as one of the broadest menus of sequencing services available among commercial laboratories. GeneDx provides testing to patients and their families in more than 55 countries.  GeneDx is a business unit of BioReference Laboratories, a wholly owned subsidiary of OPKO Health, Inc.  To learn more, please visit www.genedx.com.   For GeneDx’s complete list of testing options, please visit www.genedx.com or email [email protected]. Follow on Twitter @GeneDx and become a fan on Facebook @GeneDxLab to get real-time updates. About OPKO Health
OPKO Health is a diversified healthcare company that seeks to establish industry leading positions in large, rapidly growing markets. Our diagnostics business includes BioReference Laboratories, the nation’s third largest clinical laboratory with a core genetic testing business and a 400 person sales and marketing team to drive growth and leverage new products, including the 4Kscore® prostate cancer test and the Claros® 1 in office immunoassay platform. Our pharmaceutical business features RAYALDEE, an FDA approved treatment for SHPT in stage 3-4 CKD patients with vitamin D insufficiency (launched in November 2016), VARUBI™ for chemotherapy induced nausea and vomiting (oral formulation launched by partner TESARO and IV formulation pending FDA approval), TT401, a once or twice weekly oxyntomodulin for type 2 diabetes and obesity, in  phase 2 clinical trials, among  the new class of GLP-1 glucagon receptor dual agonists, and TT701, a selective  androgen receptor modulator  for benign prostatic hyperplasia  (phase 2). Our biologics business includes hGH-CTP, a once weekly human growth hormone in phase 3 and partnered with Pfizer; and a long-acting Factor VIIa drug for hemophilia in phase 2a.   More information available at www.opko.com. SAFE HARBOR STATEMENT
This press release contains "forward-looking statements," as that term is defined under the Private Securities Litigation Reform Act of 1995 (PSLRA), which statements may be identified by words such as "expects," "plans," "projects," "will," "may," "anticipates," "believes," "should," "intends," "estimates," and other words of similar meaning, including statements regarding our new test offerings and our ability to expand our clinical genomics programs and leverage advanced genomic technologies, as well as other non-historical statements about our expectations, beliefs or intentions regarding our business, technologies and products, financial condition, strategies or prospects. Many factors could cause our actual activities or results to differ materially from the activities and results anticipated in forward-looking statements. These factors include those described in our filings with the Securities and Exchange Commission, as well as the risks inherent in funding, developing and obtaining regulatory approvals of new, commercially-viable and competitive products and treatments. In addition, forward-looking statements may also be adversely affected by general market factors, competitive product development, product availability, federal and state regulations and legislation, the regulatory process for new products and indications, manufacturing issues that may arise, patent positions and litigation, among other factors. The forward-looking statements contained in this press release speak only as of the date the statements were made, and we do not undertake any obligation to update forward-looking statements. We intend that all forward-looking statements be subject to the safe-harbor provisions of the PSLRA. Contacts: OPKO Health, Inc.
David Malina, 305-575-4137
[email protected] GeneDx
Harpreet Somal
201-937-9496
[email protected] Media
Rooney Partners
Terry Rooney, 212-223-0689
[email protected]
or
Marion Janic, 212-223-4017
[email protected] Investors
LHA
Anne Marie Fields, 212-838-3777
[email protected]
or
Bruce Voss, 310-691-7100
[email protected]


Read more...
OPKO Health to Participate in the Barclays Global Healthcare Conference

MIAMI, March 14, 2017 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ:OPK) today announces that senior management will participate at the Barclays Global Healthcare Conference taking place March 14-16, 2017 at Loew’s Miami Beach Hotel.  Company management will deliver a corporate overview on Wednesday, March 15, 2017 at 3:20 p.m. ET. 
The Company’s presentation will be webcast live on the OPKO Investor Relations page of the corporate website at www.opko.com. To access the live webcast please log onto the OPKO website approximately fifteen minutes before the presentation to register and download any necessary audio software. The audio presentation will be available at this link for a limited time after the live presentation. About OPKO Health
OPKO Health is a diversified healthcare company that seeks to establish industry-leading positions in large, rapidly growing markets. Our diagnostics business includes BioReference Laboratories, the nation’s third-largest clinical laboratory with a core genetic testing business and a 400-person sales and marketing team to drive growth and leverage new products, including the 4Kscore® prostate cancer test and the Claros® 1 in-office immunoassay platform. Our pharmaceutical business features RAYALDEE, an FDA-approved treatment for SHPT in stage 3-4 CKD patients with vitamin D insufficiency (launched in November 2016), VARUBI™ for chemotherapy-induced nausea and vomiting (oral formulation launched by partner TESARO and IV formulation pending FDA approval), TT401, a once or twice weekly oxyntomodulin for type 2 diabetes and obesity which is a clinically advanced drug candidate among the new class of GLP-1 glucagon receptor dual agonists (phase 2), and TT701, an androgen receptor modulator for androgen deficiency indications (phase 2). Our biologics business includes hGH-CTP, a once weekly human growth hormone injection (in Phase 3 and partnered with Pfizer), and a long-acting Factor VIIa drug for hemophilia (in phase 2a).  We also have production and distribution assets worldwide, multiple strategic investments and an active business development strategy. More information available at www.opko.com. Contacts: OPKO Health, Inc.
David Malina, 305-575-4137
[email protected]  Media
Rooney Partners
Terry Rooney, 212-223-0689
[email protected] 
or
Marion Janic, 212-223-4017
[email protected]  Investors
LHA
Anne Marie Fields, 212-838-3777
[email protected] 
or
Bruce Voss, 310-691-7100
[email protected]   



Read more...
OPKO Receives EU Orphan Drug Status for its New Oligonucleotide to Treat Genetic Neurological Disorder 

MIAMI, March 08, 2017 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ:OPK) through its subsidiaries, Eirgen Pharma Limited, Ireland and OPKO Pharmaceuticals LLC, has received notification from the European Commission designating OPKO’s oligonucleotide-based AntagoNAT (CUR-1916) an orphan medicinal product under Regulation (EC) No 141/2000 for the treatment of Dravet Syndrome.  An Orphan Drug Application is under review by the U.S. FDA. There is currently no approved treatment for Dravet Syndrome in the U.S.
AntagoNAT, anti-Natural Antisense Transcripts, is an OPKO platform technology in which single strand oligonucleotide molecules are designed to interfere with regulatory gene expression in order to enhance production of endogenous functional proteins.  The AntagoNAT technology was part of CURNA Pharmaceuticals, acquired by OPKO in 2011, and then further developed in OPKO’s Miami research laboratories under the direction of Dr. Jane Hsiao, Ph.D., OPKO’s Vice Chairman and Chief Technical Officer. OPKO has studied over 250 genes and confirmed involvement of natural antisense transcripts (NAT) in their regulatory pathways. Of those, 89 genes were demonstrated to be subject to significant upregulation of mRNA in in vitro screening, and 7 AntagoNAT oligonucleotides have been validated in vivo to date. OPKO plans to initiate a clinical trial of CUR-1916 for treatment of Dravet Syndrome this year. It is worth noting that several oligonucleotide compounds have been reported to be in late phase clinical development and one has been approved by the FDA in 2016. They work by down regulating transcription (antisense) or by correcting gene defects. About EMA Orphan Designation The European Medicines Agency (EMA) grants Orphan Designation to medicines intended to treat, prevent or diagnose life threatening and debilitating diseases, with a prevalence no greater than five in 10,000 in the EU, and for which no satisfactory method of treatment, prevention or diagnosis exists, and the proposed medicine offers significant medical benefit to those with the condition. Following Orphan Designation, sponsors can access a number of incentives including market exclusivity for a ten-year period following approval, protocol assistance, and potential fee reductions. On November 24, 2016, OPKO requested Scientific Advice for the clinical development strategy of CUR-1916, and Committee for the Medicinal Products for Human Use (CHMP) has since met with OPKO and provided its advice for the CUR-1916 clinical development program. This is an important milestone for initiating a clinical trial of CUR-1916 designed to assess drug safety and significant medical benefits to patients with Dravet Syndrome. What is Dravet Syndrome? Dravet Syndrome, also called severe myoclonic epilepsy of infancy (SMEI), is a severe form of epilepsy that affects children and adults. It is caused by defects in the SCN1A genes (voltage gated sodium channel) required for the proper function of brain cells. In Dravet Syndrome, seizures begin in the first year of life, and are most often associated with elevated body temperature (febrile convulsions). Later, other types of seizures occur, including status epilepticus (seizures lasting at least 5 minutes and requiring emergency medical care). From age 2, the child’s development begins to decline or reverse, and results in impaired mental and motor skills, leading to long term disability. Dravet Syndrome is debilitating and the death rate is reported to be 10-15%. About OPKO Health, Inc.   OPKO Health is a diversified healthcare company that seeks to establish industry-leading positions in large, rapidly growing markets. Our diagnostics business includes Bio-Reference Laboratories, the nation's third-largest clinical laboratory with a core genetic testing business and a 400-person sales and marketing team to drive growth and leverage new products, including the 4Kscore® prostate cancer test and the Claros® 1 in-office immunoassay platform. Our pharmaceutical business features RAYALDEE, an FDA-approved treatment for SHPT in stage 3-4 CKD patients with vitamin D insufficiency (launched in November 2016), VARUBI™ for chemotherapy-induced nausea and vomiting (oral formulation launched by partner TESARO and IV formulation pending FDA approval), TT401, a once or twice weekly oxyntomodulin for type 2 diabetes and obesity which is a clinically advanced drug candidate among the new class of GLP-1 glucagon receptor dual agonists (phase 2), and TT701, an androgen receptor modulator for androgen deficiency indications (phase 2). Our biologics business includes hGH-CTP, a once weekly human growth hormone injection (in phase 3 and partnered with Pfizer), and a long-acting Factor VIIa drug for hemophilia (in phase 2a). We also have production and distribution assets worldwide, multiple strategic investments and an active business development strategy. More information available at www.opko.com. Cautionary Statement Regarding Forward-Looking Statements This press release contains "forward-looking statements," as that term is defined under the Private Securities Litigation Reform Act of 1995 (PSLRA), which statements may be identified by words such as "expects," "plans," "projects," "will," "may," "anticipates," "believes," "should," "intends," "estimates," and other words of similar meaning, including statements regarding expectations about CUR-1916 and its effectiveness in treating Dravet syndrome, whether the drug will receive orphan designation in the U.S., whether we will commence clinical trials for CUR-1916 this year or at all,  whether the data from any of our trials will support approval, validation and/or reimbursement for our products,  as well as other non-historical statements about our expectations, beliefs or intentions regarding our business, technologies and products, financial condition, strategies or prospects. Many factors could cause our actual activities or results to differ materially from the activities and results anticipated in forward-looking statements. These factors include those described in our Annual Reports on Form 10-K filed and to be filed with the Securities and Exchange Commission and in our other filings with the Securities and Exchange Commission, as well as the risks inherent in funding, developing and obtaining regulatory approvals of new, commercially-viable and competitive products and treatments. The forward-looking statements contained in this press release speak only as of the date the statements were made, and we do not undertake any obligation to update forward-looking statements. We intend that all forward-looking statements be subject to the safe-harbor provisions of the PSLRA. Company
OPKO Health, Inc.
Tara Mackay, 305-575-4100
Investor Relations
or
Media
Rooney Partners
Terry Rooney, 212-223-0689
[email protected]
or
Marion Janic, 212-223-4017
[email protected] or
Investors
LHA
Anne Marie Fields, 212-838-3777
[email protected]
or
Bruce Voss, 310-691-7100
[email protected]


Read more...
OPKO Subsidiary GenPath Women’s Health Announces the Availability of ClariTest™

Non-invasive prenatal test that harnesses the power of massively parallel sequencing to screen for fetal chromosomal abnormalities

MIAMI, March 07, 2017 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ:OPK) announces that GenPath Women’s Health, a business unit of OPKO Health subsidiary BioReference Laboratories, will offer ClariTest™, a non-invasive prenatal test (NIPT) initially to be performed at Illumina, Inc. (NASDAQ:ILMN) on the Verifi™ platform.  This platform utilizes massively parallel sequencing technology to screen for trisomies 13, 18, 21 and sex chromosome abnormalities, with the option to screen for 5 microdeletions including 22q11.2 (DiGeorge syndrome).  ClariTest™ can be performed as early as 10 weeks of gestational age, can be performed in twin and egg donor pregnancies, has excellent sensitivity and specificity, and has the lowest failure rate in the industry.
Illumina’s most recent clinical evidence study of Verifi™ was comprised of more than 85,000 clinical samples and demonstrated observed sensitivity and specificity of trisomy 21 at greater than 99%.  Trisomy 18 and trisomy 13 had observed sensitivity at greater than 97% and specificity at greater than 99%. With the industry’s lowest failure rate at 0.1%, Illumina’s Verifi™ service can reduce maternal anxiety by requiring fewer redraws and reliably providing fetal genetic information to a greater number of patients and providers. GenPath Women’s Health will ultimately develop and validate its own laboratory-developed test for NIPT using Illumina’s sequencing technology. Adoption of Illumina’s Verifi™ test allows GenPath to continue to serve the NIPT market using the immense power of whole genome sequencing while developing its own NIPT offering. “We believe the best way to improve patient care is to unlock the power of whole genome sequencing. We are pleased to partner with BioReference and GenPath Women’s Health to expand the use of Illumina technology for women’s health.  The partnership further extends Illumina’s strategy to enable a broader number of customers to offer NIPT on our sequencing technology,” said Jeff Hawkins, Vice President and General Manager of Reproductive Genetic Health at Illumina. “NIPT testing has become an incredibly valuable addition to prenatal care and we are pleased to offer what we believe to be the most technically advanced NIPT test available on the market.  ClariTest is a safe option to help pregnant women and their physicians screen patients who are at an increased risk of a fetal chromosome abnormality,” said Gregory S. Henderson, M.D., Ph.D., President of BioReference Laboratories. “Patient care is foremost at BioReference and ClariTest provides highly accurate results at an early gestational age.  ClariTest is based on the latest advances in technology, offering superior detection rates compared to conventional screening methods for fetal chromosome abnormalities and can significantly reduce the need for invasive testing, which is associated with an increased risk for adverse pregnancy outcomes, including pregnancy loss.” ClariTest is available from GenPath Women’s Health. As a convenience to patients and physicians alike, the laboratory provides easy-to-read results reports available within 5-7 days after testing, access to an industry-leading team of genetic counselors, contracts with most national insurance carriers, direct-to-patient pricing as part of the Community Health Advocacy Program, the ability to interface with most EMR/EHRs, a comprehensive network of patient service centers and other ancillary support services. About OPKO Health, Inc.: 
OPKO Health is a diversified healthcare company that seeks to establish industry-leading positions in large, rapidly growing markets. Our diagnostics business includes BioReference Laboratories, the nation's third-largest clinical laboratory with a core genetic testing business and a 400-person sales and marketing team to drive growth and leverage new products, including the 4Kscore® prostate cancer test and the Claros® 1 in-office immunoassay platform. Our pharmaceutical business features RAYALDEE, an FDA-approved treatment for SHPT in stage 3-4 CKD patients with vitamin D insufficiency (launched in November 2016), VARUBI™ for chemotherapy-induced nausea and vomiting (oral formulation launched by partner TESARO and IV formulation pending FDA approval), TT401, a once- or twice-weekly oxyntomodulin for type 2 diabetes and obesity which is a clinically advanced drug candidate among the new class of GLP-1 glucagon receptor dual agonists (phase 2), and TT701, an androgen receptor modulator for androgen deficiency indications (phase 2).  Our biologics business includes hGH-CTP, a once-weekly human growth hormone injection (in phase 3 and partnered with Pfizer) and a long-acting Factor VIIa drug for hemophilia (in phase 2a). We also have production and distribution assets worldwide, multiple strategic investments and an active business development strategy. More information is available at www.opko.com. About GenPath Women’s Health:
GenPath Women’s Health and its parent company BioReference Laboratories Inc. are members of the OPKO Health, Inc. (NASDAQ:OPK) group of companies. GenPath Women’s Health is a full-service laboratory offering a complete menu of tests for the OB-GYN and women’s health providers. Since its inception in 2005, GenPath Women’s Health has risen to become one of the premier specialty labs in the country, including the development of an innovative technology platform for sexually transmitted and other vaginal infections, pan-ethnic carrier testing and maternal risk assessment and prenatal diagnosis. GenPath has grown and evolved to become the One Lab for every phase of a patient’s life, offering solutions to all women’s health testing and service needs. In 2015, GenPath launched an industry-leading line of hereditary cancer testing. More information is available at http://www.genpathdiagnostics.com/womens-health/.   This press release contains "forward-looking statements," as that term is defined under the Private Securities Litigation Reform Act of 1995 (PSLRA), which statements may be identified by words such as "expects," "plans," "projects," "will," "may," "anticipates," "believes," "should," "intends," "estimates," and other words of similar meaning, including statements regarding expected benefits of the ClariTest and the performance of the test, whether it will reliably provide fetal genetic information, whether it offers superior detection rates and will significantly reduce the need for invasive testing,  as well as other non-historical statements about our expectations, beliefs or intentions regarding our business, technologies and products, financial condition, strategies or prospects. Many factors could cause our actual activities or results to differ materially from the activities and results anticipated in forward-looking statements. These factors include those described in our filings with the Securities and Exchange Commission, as well as the risks inherent in funding, developing and obtaining regulatory approvals of new, commercially-viable and competitive products and treatments. In addition, forward-looking statements may also be adversely affected by general market factors, competitive product development, product availability, federal and state regulations and legislation, the regulatory process for new products and indications, manufacturing issues that may arise, patent positions and litigation, among other factors. The forward-looking statements contained in this press release speak only as of the date the statements were made, and we do not undertake any obligation to update forward-looking statements. We intend that all forward-looking statements be subject to the safe-harbor provisions of the PSLRA. Contacts: OPKO Health, Inc.
David Malina, 305-575-4137 GenPath Women’s Health
Kesha Walker, 201-791-2600 x8651 Media
Rooney Partners
Terry Rooney, 212-223-0689
[email protected]
or
Marion Janic, 212-223-4017
[email protected]  Investors
LHA
Anne Marie Fields, 212-838-3777
[email protected]  



Read more...
OPKO Health Appoints Dr. Akhtar Ashfaq as Renal Division Senior Vice President, Clinical Research and Development

MIAMI, March 03, 2017 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ:OPK) announced the appointment of Akhtar Ashfaq, MD, FACP, FASN to the position of Senior Vice President, Clinical Research and Development of OPKO Health’s Renal Division, effective immediately.  In this role, Dr. Ashfaq will support the ongoing adoption of RAYALDEE® (calcifediol) extended-release capsules by healthcare professionals who care for patients with stage 3 or 4 chronic kidney disease (CKD). He will lead the further development of RAYALDEE for the treatment of secondary hyperparathyroidism (SHPT) in adults with stage 5 CKD and vitamin D insufficiency who require regular hemodialysis.  He also will lead the development of ALPHAREN® (fermagate) tablets for the treatment of hyperphosphatemia in adults with stage 5 CKD.
Dr. Ashfaq was previously with AstraZeneca, where he served as Executive Director and Head of the CKD Program within Global Medical Affairs.  Prior to Astra Zeneca, Dr. Ashfaq was with Amgen where he served as Medical Director and North American Medical Lead for Epogen and Aranesp.  He is an academic nephrologist by training and has more than 15 years of clinical experience.  “We are proud to have Dr. Ashfaq join our growing team that is focused on developing and commercializing new products for CKD patients,” stated Phillip Frost, MD, Chairman and Chief Executive Officer of OPKO Health.  “Dr. Ashfaq will play a major role in expanding our renal product offerings which are designed to improve the treatment of SHPT and hyperphosphatemia in CKD patients.” About OPKO Health, Inc.
OPKO Health is a diversified healthcare company that seeks to establish industry-leading positions in large, rapidly growing markets. Our diagnostics business includes Bio-Reference Laboratories, the nation's third-largest clinical laboratory with a core genetic testing business and a 400-person sales and marketing team to drive growth and leverage new products, including the 4Kscore® prostate cancer test and the Claros® 1 in-office immunoassay platform. Our pharmaceutical business features RAYALDEE, an FDA-approved treatment for SHPT in stage 3-4 CKD patients with vitamin D insufficiency (launched in November 2016), VARUBI™ for chemotherapy-induced nausea and vomiting (oral formulation launched by partner TESARO and IV formulation pending FDA approval), TT401, a once or twice weekly oxyntomodulin for type 2 diabetes and obesity which is a clinically advanced drug candidate among the new class of GLP-1 glucagon receptor dual agonists (phase 2), and TT701, an androgen receptor modulator for androgen deficiency indications (phase 2).  Our biologics business includes hGH-CTP, a once-weekly human growth hormone injection (in phase 3 and partnered with Pfizer) and a long-acting Factor VIIa drug for hemophilia (in phase 2a). We also have production and distribution assets worldwide, multiple strategic investments and an active business development strategy. More information is available at www.opko.com. SAFE HARBOR STATEMENT
This press release contains "forward-looking statements," as that term is defined under the Private Securities Litigation Reform Act of 1995 (PSLRA), which statements may be identified by words such as "expects," "plans," "projects," "will," "may," "anticipates," "believes," "should," "intends," "estimates," and other words of similar meaning, including statements regarding our product development efforts and our ability to expand our renal product offerings, as well as other non-historical statements about our expectations, beliefs or intentions regarding our business, technologies and products, financial condition, strategies or prospects. Many factors could cause our actual activities or results to differ materially from the activities and results anticipated in forward-looking statements. These factors include those described in our filings with the Securities and Exchange Commission, as well as the risks inherent in funding, developing and obtaining regulatory approvals of new, commercially-viable and competitive products and treatments. In addition, forward-looking statements may also be adversely affected by general market factors, competitive product development, product availability, federal and state regulations and legislation, the regulatory process for new products and indications, manufacturing issues that may arise, patent positions and litigation, among other factors. The forward-looking statements contained in this press release speak only as of the date the statements were made, and we do not undertake any obligation to update forward-looking statements. We intend that all forward-looking statements be subject to the safe-harbor provisions of the PSLRA. Contacts: OPKO Health, Inc. David Malina, 305-575-4137
Investor Relations or Media Rooney Partners Terry Rooney, 212-223-0689
[email protected] or Marion Janic, 212-223-4017
[email protected] or Investors LHA Anne Marie Fields, 212-838-3777
[email protected] or Bruce Voss, 310-691-7100
[email protected]


Read more...

Ratios

vs
industry
vs
history
PB Ratio 2.07
OPK's PB Ratio is ranked higher than
64% of the 770 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 3.03 vs. OPK: 2.07 )
Ranked among companies with meaningful PB Ratio only.
OPK' s PB Ratio Range Over the Past 10 Years
Min: 1.99  Med: 8.64 Max: 800
Current: 2.07
1.99
800
PS Ratio 3.51
OPK's PS Ratio is ranked lower than
56% of the 721 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 2.90 vs. OPK: 3.51 )
Ranked among companies with meaningful PS Ratio only.
OPK' s PS Ratio Range Over the Past 10 Years
Min: 3.36  Med: 31.62 Max: 158.13
Current: 3.51
3.36
158.13
Price-to-Free-Cash-Flow 555.00
OPK's Price-to-Free-Cash-Flow is ranked lower than
98% of the 226 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 23.83 vs. OPK: 555.00 )
Ranked among companies with meaningful Price-to-Free-Cash-Flow only.
OPK' s Price-to-Free-Cash-Flow Range Over the Past 10 Years
Min: 22.54  Med: 40 Max: 850.71
Current: 555
22.54
850.71
Price-to-Operating-Cash-Flow 136.32
OPK's Price-to-Operating-Cash-Flow is ranked lower than
95% of the 288 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 17.62 vs. OPK: 136.32 )
Ranked among companies with meaningful Price-to-Operating-Cash-Flow only.
OPK' s Price-to-Operating-Cash-Flow Range Over the Past 10 Years
Min: 20.71  Med: 38.9 Max: 208.95
Current: 136.32
20.71
208.95
EV-to-EBIT -64.64
OPK's EV-to-EBIT is ranked lower than
99.99% of the 776 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 20.99 vs. OPK: -64.64 )
Ranked among companies with meaningful EV-to-EBIT only.
OPK' s EV-to-EBIT Range Over the Past 10 Years
Min: -130.8  Med: -34.1 Max: 203.7
Current: -64.64
-130.8
203.7
EV-to-EBITDA 140.29
OPK's EV-to-EBITDA is ranked lower than
97% of the 797 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 15.26 vs. OPK: 140.29 )
Ranked among companies with meaningful EV-to-EBITDA only.
OPK' s EV-to-EBITDA Range Over the Past 10 Years
Min: -146.6  Med: -34.2 Max: 539.9
Current: 140.29
-146.6
539.9
Current Ratio 1.84
OPK's Current Ratio is ranked lower than
63% of the 700 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 2.55 vs. OPK: 1.84 )
Ranked among companies with meaningful Current Ratio only.
OPK' s Current Ratio Range Over the Past 10 Years
Min: 1.22  Med: 3.44 Max: 42.13
Current: 1.84
1.22
42.13
Quick Ratio 1.66
OPK's Quick Ratio is ranked lower than
55% of the 699 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 1.85 vs. OPK: 1.66 )
Ranked among companies with meaningful Quick Ratio only.
OPK' s Quick Ratio Range Over the Past 10 Years
Min: 1.08  Med: 3.44 Max: 42.13
Current: 1.66
1.08
42.13
Days Inventory 25.39
OPK's Days Inventory is ranked higher than
93% of the 689 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 117.29 vs. OPK: 25.39 )
Ranked among companies with meaningful Days Inventory only.
OPK' s Days Inventory Range Over the Past 10 Years
Min: 25.39  Med: 191.87 Max: 500.07
Current: 25.39
25.39
500.07
Days Sales Outstanding 65.82
OPK's Days Sales Outstanding is ranked higher than
58% of the 636 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 75.05 vs. OPK: 65.82 )
Ranked among companies with meaningful Days Sales Outstanding only.
OPK' s Days Sales Outstanding Range Over the Past 10 Years
Min: 38.86  Med: 153.78 Max: 727.85
Current: 65.82
38.86
727.85
Days Payable 31.85
OPK's Days Payable is ranked lower than
84% of the 586 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 70.53 vs. OPK: 31.85 )
Ranked among companies with meaningful Days Payable only.
OPK' s Days Payable Range Over the Past 10 Years
Min: 31.85  Med: 108.04 Max: 1499.3
Current: 31.85
31.85
1499.3

Buy Back

vs
industry
vs
history
3-Year Average Share Buyback Ratio -10.60
OPK's 3-Year Average Share Buyback Ratio is ranked lower than
70% of the 442 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: -4.30 vs. OPK: -10.60 )
Ranked among companies with meaningful 3-Year Average Share Buyback Ratio only.
OPK' s 3-Year Average Share Buyback Ratio Range Over the Past 10 Years
Min: -146.3  Med: -14.4 Max: 0.4
Current: -10.6
-146.3
0.4

Valuation & Return

vs
industry
vs
history
Price-to-Intrinsic-Value-Projected-FCF 2.75
OPK's Price-to-Intrinsic-Value-Projected-FCF is ranked lower than
52% of the 288 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 2.56 vs. OPK: 2.75 )
Ranked among companies with meaningful Price-to-Intrinsic-Value-Projected-FCF only.
OPK' s Price-to-Intrinsic-Value-Projected-FCF Range Over the Past 10 Years
Min: 2.75  Med: 7.61 Max: 62.44
Current: 2.75
2.75
62.44
Price-to-Median-PS-Value 0.11
OPK's Price-to-Median-PS-Value is ranked higher than
98% of the 645 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 1.13 vs. OPK: 0.11 )
Ranked among companies with meaningful Price-to-Median-PS-Value only.
OPK' s Price-to-Median-PS-Value Range Over the Past 10 Years
Min: 0.11  Med: 1.25 Max: 30
Current: 0.11
0.11
30
Earnings Yield (Greenblatt) % -1.55
OPK's Earnings Yield (Greenblatt) % is ranked lower than
73% of the 1046 Companies
in the Global Drug Manufacturers - Specialty & Generic industry.

( Industry Median: 3.36 vs. OPK: -1.55 )
Ranked among companies with meaningful Earnings Yield (Greenblatt) % only.
OPK' s Earnings Yield (Greenblatt) % Range Over the Past 10 Years
Min: -1.55  Med: 0.5 Max: 0.5
Current: -1.55
-1.55
0.5

More Statistics

Revenue (TTM) (Mil) $1,222
EPS (TTM) $ -0.06
Beta2.42
Short Percentage of Float13.43%
52-Week Range $7.11 - 12.15
Shares Outstanding (Mil)558.22

Analyst Estimate

Dec17 Dec18 Dec19
Revenue (Mil $) 612 795 1,114
EPS ($) -0.20 0.02 0.35
EPS without NRI ($) -0.20 0.02 0.35
EPS Growth Rate
(Future 3Y To 5Y Estimate)
12.00%
Dividends per Share ($)
» More Articles for OPK

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OPKO Receives FDA Orphan Drug Status for its New Oligonucleotide to Treat Genetic Neurological Disor Mar 22 2017 
OPKO Health's GeneDx to have Significant Presence at ACMG 2017 Mar 14 2017 
OPKO Health to Participate in the Barclays Global Healthcare Conference Mar 14 2017 
OPKO Receives EU Orphan Drug Status for its New Oligonucleotide to Treat Genetic Neurological Disord Mar 08 2017 
OPKO Subsidiary GenPath Women’s Health Announces the Availability of ClariTest™ Mar 07 2017 

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