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GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength : 9/10

vs
industry
vs
history
Cash to Debt No Debt
PBYI's Cash to Debt is ranked higher than
82% of the 1430 Companies
in the Global Biotechnology industry.

( Industry Median: 54.60 vs. PBYI: No Debt )
PBYI' s 10-Year Cash to Debt Range
Min: No Debt   Max: No Debt
Current: No Debt

Interest Coverage No Debt
PBYI's Interest Coverage is ranked higher than
57% of the 650 Companies
in the Global Biotechnology industry.

( Industry Median: 10000.00 vs. PBYI: No Debt )
PBYI' s 10-Year Interest Coverage Range
Min: 9999.99   Max: 9999.99
Current: No Debt

F-Score: 2
Z-Score: 92.04
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth : 3/10

vs
industry
vs
history
ROE (%) -100.19
PBYI's ROE (%) is ranked higher than
56% of the 1309 Companies
in the Global Biotechnology industry.

( Industry Median: -30.42 vs. PBYI: -100.19 )
PBYI' s 10-Year ROE (%) Range
Min: -141.23   Max: -37.64
Current: -100.19

-141.23
-37.64
ROA (%) -82.97
PBYI's ROA (%) is ranked higher than
54% of the 1438 Companies
in the Global Biotechnology industry.

( Industry Median: -25.96 vs. PBYI: -82.97 )
PBYI' s 10-Year ROA (%) Range
Min: -1700   Max: -36.94
Current: -82.97

-1700
-36.94
ROC (Joel Greenblatt) (%) -7519.03
PBYI's ROC (Joel Greenblatt) (%) is ranked higher than
53% of the 1397 Companies
in the Global Biotechnology industry.

( Industry Median: -335.68 vs. PBYI: -7519.03 )
PBYI' s 10-Year ROC (Joel Greenblatt) (%) Range
Min: -7408.23   Max: -2978.59
Current: -7519.03

-7408.23
-2978.59
EBITDA Growth (3Y)(%) 53.30
PBYI's EBITDA Growth (3Y)(%) is ranked higher than
97% of the 816 Companies
in the Global Biotechnology industry.

( Industry Median: -2.40 vs. PBYI: 53.30 )
PBYI' s 10-Year EBITDA Growth (3Y)(%) Range
Min: 0   Max: 598.6
Current: 53.3

0
598.6
EPS Growth (3Y)(%) 53.00
PBYI's EPS Growth (3Y)(%) is ranked higher than
96% of the 799 Companies
in the Global Biotechnology industry.

( Industry Median: -6.70 vs. PBYI: 53.00 )
PBYI' s 10-Year EPS Growth (3Y)(%) Range
Min: 0   Max: 883
Current: 53

0
883
» PBYI's 10-Y Financials

Financials


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow

» Details

Guru Trades

Q1 2014

PBYI Guru Trades in Q1 2014

Pioneer Investments 30,901 sh (New)
Jim Simons 12,600 sh (New)
Steven Cohen 78,938 sh (+1261.00%)
» More
Q2 2014

PBYI Guru Trades in Q2 2014

Steven Cohen 327,900 sh (unchged)
Pioneer Investments Sold Out
Jim Simons Sold Out
» More
Q3 2014

PBYI Guru Trades in Q3 2014

Jim Simons 30,200 sh (New)
RS Investment Management 92,188 sh (New)
Steven Cohen Sold Out
» More
Q4 2014

PBYI Guru Trades in Q4 2014

Jim Simons Sold Out
RS Investment Management Sold Out
» More
» Details

Insider Trades

Latest Guru Trades with PBYI

(List those with share number changes of more than 20%, or impact to portfolio more than 0.1%)

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Ratios

vs
industry
vs
history
P/B 58.50
PBYI's P/B is ranked lower than
64% of the 1590 Companies
in the Global Biotechnology industry.

( Industry Median: 6.80 vs. PBYI: 58.50 )
PBYI' s 10-Year P/B Range
Min: 0   Max: 62.4
Current: 58.5

0
62.4
EV-to-EBIT -52.67
PBYI's EV-to-EBIT is ranked higher than
81% of the 1590 Companies
in the Global Biotechnology industry.

( Industry Median: 0.00 vs. PBYI: -52.67 )
PBYI' s 10-Year EV-to-EBIT Range
Min: 0   Max: 0
Current: -52.67

Current Ratio 3.36
PBYI's Current Ratio is ranked higher than
68% of the 1394 Companies
in the Global Biotechnology industry.

( Industry Median: 4.44 vs. PBYI: 3.36 )
PBYI' s 10-Year Current Ratio Range
Min: 1   Max: 91.42
Current: 3.36

1
91.42
Quick Ratio 3.36
PBYI's Quick Ratio is ranked higher than
70% of the 1394 Companies
in the Global Biotechnology industry.

( Industry Median: 4.25 vs. PBYI: 3.36 )
PBYI' s 10-Year Quick Ratio Range
Min: 1   Max: 91.42
Current: 3.36

1
91.42

Valuation & Return

vs
industry
vs
history
Price/Net Cash 72.80
PBYI's Price/Net Cash is ranked higher than
56% of the 1590 Companies
in the Global Biotechnology industry.

( Industry Median: 105.00 vs. PBYI: 72.80 )
PBYI' s 10-Year Price/Net Cash Range
Min: 4.69   Max: 60.47
Current: 72.8

4.69
60.47
Price/Net Current Asset Value 71.90
PBYI's Price/Net Current Asset Value is ranked higher than
53% of the 1590 Companies
in the Global Biotechnology industry.

( Industry Median: 41.60 vs. PBYI: 71.90 )
PBYI' s 10-Year Price/Net Current Asset Value Range
Min: 4.26   Max: 55.83
Current: 71.9

4.26
55.83
Price/Tangible Book 58.70
PBYI's Price/Tangible Book is ranked lower than
63% of the 1590 Companies
in the Global Biotechnology industry.

( Industry Median: 9.90 vs. PBYI: 58.70 )
PBYI' s 10-Year Price/Tangible Book Range
Min: 4.18   Max: 50.76
Current: 58.7

4.18
50.76
Earnings Yield (Greenblatt) -1.90
PBYI's Earnings Yield (Greenblatt) is ranked higher than
79% of the 1388 Companies
in the Global Biotechnology industry.

( Industry Median: -5.90 vs. PBYI: -1.90 )
PBYI' s 10-Year Earnings Yield (Greenblatt) Range
Min: -2.3   Max: 0
Current: -1.9

-2.3
0

Business Description

Industry: Biotechnology » Biotechnology
Compare: » details
Traded in other countries:0PB.Germany,
Puma Biotechnology Inc was incorporated in Delaware on April 27, 2007. The Company is a biopharmaceutical company. It is engaged in the acquisition, development and commercialization of products to enhance cancer care It is engaged in-licensing drug candidates that are undergoing or have already completed initial clinical testing for the treatment of cancer and then seek to further develop those drug candidates for commercial use. The Company currently licenses the rights to three drug candidates: PB272 (neratinib (oral)), which are being developed for the treatment of breast cancer patients, non-small cell lung cancer and patients with HER2 mutation-positive solid tumors; PB272 (neratinib (intravenous)), which are being developed for the treatment of cancer patients; and PB357, which it believes can serve as a backup compound to PB272, and which are being evaluated for further development. The Company focused on developing neratinib for the treatment of patients with human epidermal growth factor receptor type 2, or HER2-positive, breast cancer, HER2 mutated non-small cell lung cancer, HER2-negative breast cancer that has a HER2 mutation and other solid tumors that have an activating mutation in HER2. Therapeutic strategies, such as the use of Herceptin (trastuzumab), Perjeta (pertuzumab), and Kadcyla (T-DM1), produced by Genentech, and Tykerb (lapatinib), produced by GlaxoSmithKline, given either alone or in combination with chemotherapy, have been developed to improve the treatment of this cancer by binding to the HER2 protein. The Company licenses the exclusive rights to its current drug candidates from Pfizer Inc., or Pfizer, which had previously been responsible for the clinical trials regarding neratinib. The Company's competitors include Genentech, GlaxoSmithKline, Roche, Boehringer Ingelheim, Takeda, Array Biopharma and Ambit Biosciences.
» More Articles for PBYI

Headlines

Articles On GuruFocus.com
Hall of Fame/ Hall of Shame: The Best and Worst Recommendations of 2014 Jan 09 2015 


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