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GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength : 5/10

vs
industry
vs
history
Cash to Debt 1.29
PLX's Cash to Debt is ranked higher than
58% of the 896 Companies
in the Global Biotechnology industry.

( Industry Median: 171.30 vs. PLX: 1.29 )
PLX' s 10-Year Cash to Debt Range
Min: 1.29   Max: No Debt
Current: 1.29

Equity to Asset -0.24
PLX's Equity to Asset is ranked lower than
53% of the 759 Companies
in the Global Biotechnology industry.

( Industry Median: 0.67 vs. PLX: -0.24 )
PLX' s 10-Year Equity to Asset Range
Min: -0.5   Max: 0.88
Current: -0.24

-0.5
0.88
F-Score: 1
Z-Score: -0.81
M-Score: -0.26
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth : 4/10

vs
industry
vs
history
Operating margin (%) -235.53
PLX's Operating margin (%) is ranked higher than
62% of the 785 Companies
in the Global Biotechnology industry.

( Industry Median: -66.98 vs. PLX: -235.53 )
PLX' s 10-Year Operating margin (%) Range
Min: -8239.43   Max: -14.61
Current: -235.53

-8239.43
-14.61
Net-margin (%) -241.38
PLX's Net-margin (%) is ranked higher than
61% of the 785 Companies
in the Global Biotechnology industry.

( Industry Median: -56.37 vs. PLX: -241.38 )
PLX' s 10-Year Net-margin (%) Range
Min: -8103.09   Max: -14.27
Current: -241.38

-8103.09
-14.27
ROA (%) -24.52
PLX's ROA (%) is ranked higher than
69% of the 894 Companies
in the Global Biotechnology industry.

( Industry Median: -18.90 vs. PLX: -24.52 )
PLX' s 10-Year ROA (%) Range
Min: -427.74   Max: 1.8
Current: -24.52

-427.74
1.8
ROC (Joel Greenblatt) (%) -197.77
PLX's ROC (Joel Greenblatt) (%) is ranked higher than
71% of the 872 Companies
in the Global Biotechnology industry.

( Industry Median: -196.35 vs. PLX: -197.77 )
PLX' s 10-Year ROC (Joel Greenblatt) (%) Range
Min: -758.19   Max: -0.68
Current: -197.77

-758.19
-0.68
Revenue Growth (%) 14.50
PLX's Revenue Growth (%) is ranked higher than
87% of the 589 Companies
in the Global Biotechnology industry.

( Industry Median: -1.30 vs. PLX: 14.50 )
PLX' s 10-Year Revenue Growth (%) Range
Min: 0   Max: 236.2
Current: 14.5

0
236.2
EBITDA Growth (%) -7.60
PLX's EBITDA Growth (%) is ranked higher than
76% of the 597 Companies
in the Global Biotechnology industry.

( Industry Median: -10.30 vs. PLX: -7.60 )
PLX' s 10-Year EBITDA Growth (%) Range
Min: -53.6   Max: 84.2
Current: -7.6

-53.6
84.2
EPS Growth (%) -5.90
PLX's EPS Growth (%) is ranked higher than
79% of the 617 Companies
in the Global Biotechnology industry.

( Industry Median: -12.80 vs. PLX: -5.90 )
PLX' s 10-Year EPS Growth (%) Range
Min: -49.7   Max: 54.6
Current: -5.9

-49.7
54.6
» PLX's 10-Y Financials

Financials


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow

» Details

Guru Trades

Q1 2013

PLX Guru Trades in Q1 2013

Manning & Napier Advisors, Inc 1,433,010 sh (+4.14%)
Jean-Marie Eveillard 500,000 sh (-23.08%)
» More
Q2 2013

PLX Guru Trades in Q2 2013

Jean-Marie Eveillard 500,000 sh (unchged)
Manning & Napier Advisors, Inc 159,710 sh (-88.85%)
» More
Q3 2013

PLX Guru Trades in Q3 2013

Jean-Marie Eveillard 500,000 sh (unchged)
Manning & Napier Advisors, Inc Sold Out
» More
Q4 2013

PLX Guru Trades in Q4 2013

Jean-Marie Eveillard 700,000 sh (+40%)
» More
» Details

Insider Trades

Latest Guru Trades with PLX

GuruDate Trades Impact to Portfolio Price Range * (?) Current Price Change from Average Current Shares
Jean-Marie Eveillard 2013-12-31 Add 40%$3.72 - $4.52 $ 4.15-1%700000
Jean-Marie Eveillard 2013-03-31 Reduce -23.08%$5.03 - $6.15 $ 4.15-25%500000
Jean-Marie Eveillard 2012-06-30 New Buy0.01%$5.57 - $7.27 $ 4.15-36%650000
Premium More recent guru trades are included for Premium Members only!!
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Peter Lynch Chart ( What is Peter Lynch Charts )

Ratios

vs
industry
vs
history
P/S 33.30
PLX's P/S is ranked lower than
74% of the 771 Companies
in the Global Biotechnology industry.

( Industry Median: 10.27 vs. PLX: 33.30 )
PLX' s 10-Year P/S Range
Min: 11.07   Max: 748
Current: 33.3

11.07
748
EV-to-EBIT 50.00
PLX's EV-to-EBIT is ranked lower than
71% of the 468 Companies
in the Global Biotechnology industry.

( Industry Median: 20.00 vs. PLX: 50.00 )
PLX' s 10-Year EV-to-EBIT Range
Min: 44.9   Max: 58
Current: 50

44.9
58

Valuation & Return

vs
industry
vs
history
Price/Median PS Value 0.80
PLX's Price/Median PS Value is ranked higher than
78% of the 725 Companies
in the Global Biotechnology industry.

( Industry Median: 1.10 vs. PLX: 0.80 )
PLX' s 10-Year Price/Median PS Value Range
Min: 0.01   Max: 3.42
Current: 0.8

0.01
3.42
Forward Rate of Return (Yacktman) -19.84
PLX's Forward Rate of Return (Yacktman) is ranked higher than
70% of the 669 Companies
in the Global Biotechnology industry.

( Industry Median: -9.87 vs. PLX: -19.84 )
PLX' s 10-Year Forward Rate of Return (Yacktman) Range
Min: -24.8   Max: 38.3
Current: -19.84

-24.8
38.3

Business Description

Industry: Biotechnology » Biotechnology
Compare:NVO, AMGN, GILD, BIIB, CELG » details
Traded in other countries:PBD.Germany
Protalix BioTherapeutics, Inc. was originally formed as an Embassy Acquisition Corp., a Florida corporation, in November 2005 and changed its name to Orthodontix, Inc., in April, 1992. On December 31, 2006, it acquired, through a merger with its wholly-owned subsidiary, Protalix Acquisition Co. Ltd., all of the outstanding shares of Protalix Ltd., in exchange for shares of its common stock. As a result, Protalix Ltd. is now its wholly-owned subsidiary. In connection with the merger, it completed a one-for-ten reverse stock split and on February 26, 2007, it changed its name to Protalix BioTherapeutics, Inc. The Company and its wholly-owned subsidiary, Protalix Ltd. operate as biopharmaceutical companies focused on the development and commercialization of recombinant therapeutic proteins based on the Company's proprietary ProCellEx protein expression system or ProCellEx. The Company's product development candidate is prGCD for the treatment of Gaucher disease, which the Company is developing using its ProCellEx protein expression system. Using its ProCellEx system, it is developing a pipeline of proprietary and biosimilar or 'generic' versions of recombinant therapeutic proteins based on its plant cell-based expression technology that target large, established pharmaceutical markets and that rely upon known biological mechanisms of action. The Company's initial commercial focus has been on complex therapeutic proteins, including proteins for the treatment of genetic disorders, such as Gaucher disease and Fabry disease. The biotechnology and pharmaceutical industries are characterized by rapidly evolving technology and significant competition. Competition from numerous existing companies and others entering the fields in which it operates is intense and expected to increase. ProCellEx(tm) is its trademark. The testing, manufacture, distribution, advertising and marketing of drug products are subject to extensive regulation by federal, state and local governmental authorities in the United States, including the FDA, and by similar authorities in other countries.

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