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GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength : 8/10

vs
industry
vs
history
Cash to Debt No Debt
ZIOP's Cash to Debt is ranked higher than
80% of the 900 Companies
in the Global Biotechnology industry.

( Industry Median: 83.08 vs. ZIOP: No Debt )
ZIOP' s 10-Year Cash to Debt Range
Min: No Debt   Max: No Debt
Current: No Debt

Equity to Asset 0.66
ZIOP's Equity to Asset is ranked higher than
71% of the 742 Companies
in the Global Biotechnology industry.

( Industry Median: 0.68 vs. ZIOP: 0.66 )
ZIOP' s 10-Year Equity to Asset Range
Min: -4.5   Max: 0.69
Current: 0.66

-4.5
0.69
Interest Coverage No Debt
ZIOP's Interest Coverage is ranked higher than
85% of the 408 Companies
in the Global Biotechnology industry.

( Industry Median: 10000.00 vs. ZIOP: No Debt )
ZIOP' s 10-Year Interest Coverage Range
Min: 9999.99   Max: 9999.99
Current: No Debt

F-Score: 3
Z-Score: -0.42
M-Score: -2.52
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth : 3/10

vs
industry
vs
history
Operating margin (%) -7214.13
ZIOP's Operating margin (%) is ranked higher than
51% of the 790 Companies
in the Global Biotechnology industry.

( Industry Median: -71.36 vs. ZIOP: -7214.13 )
ZIOP' s 10-Year Operating margin (%) Range
Min: -12771.13   Max: -1333.33
Current: -7214.13

-12771.13
-1333.33
Net-margin (%) -7138.38
ZIOP's Net-margin (%) is ranked higher than
51% of the 790 Companies
in the Global Biotechnology industry.

( Industry Median: -59.60 vs. ZIOP: -7138.38 )
ZIOP' s 10-Year Net-margin (%) Range
Min: -12016.5   Max: -1333.33
Current: -7138.38

-12016.5
-1333.33
ROE (%) -115.64
ZIOP's ROE (%) is ranked higher than
54% of the 811 Companies
in the Global Biotechnology industry.

( Industry Median: -20.60 vs. ZIOP: -115.64 )
ZIOP' s 10-Year ROE (%) Range
Min: -374.4   Max: -27.22
Current: -115.64

-374.4
-27.22
ROA (%) -79.59
ZIOP's ROA (%) is ranked higher than
55% of the 889 Companies
in the Global Biotechnology industry.

( Industry Median: -17.36 vs. ZIOP: -79.59 )
ZIOP' s 10-Year ROA (%) Range
Min: -4000   Max: -15.38
Current: -79.59

-4000
-15.38
ROC (Joel Greenblatt) (%) -7205.12
ZIOP's ROC (Joel Greenblatt) (%) is ranked higher than
54% of the 861 Companies
in the Global Biotechnology industry.

( Industry Median: -243.56 vs. ZIOP: -7205.12 )
ZIOP' s 10-Year ROC (Joel Greenblatt) (%) Range
Min: -9701.98   Max: -2368.88
Current: -7205.12

-9701.98
-2368.88
EBITDA Growth (%) 7.60
ZIOP's EBITDA Growth (%) is ranked higher than
86% of the 598 Companies
in the Global Biotechnology industry.

( Industry Median: -10.50 vs. ZIOP: 7.60 )
ZIOP' s 10-Year EBITDA Growth (%) Range
Min: -30.4   Max: 88.9
Current: 7.6

-30.4
88.9
EPS Growth (%) -2.40
ZIOP's EPS Growth (%) is ranked higher than
82% of the 630 Companies
in the Global Biotechnology industry.

( Industry Median: -12.60 vs. ZIOP: -2.40 )
ZIOP' s 10-Year EPS Growth (%) Range
Min: -38.5   Max: 86.1
Current: -2.4

-38.5
86.1
» ZIOP's 10-Y Financials

Financials


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow

» Details

Guru Trades

Q2 2013

ZIOP Guru Trades in Q2 2013

Chuck Royce 660,000 sh (New)
Steven Cohen 888,000 sh (+18.4%)
Jean-Marie Eveillard Sold Out
Kyle Bass Sold Out
Paul Tudor Jones 25,100 sh (-60.22%)
» More
Q3 2013

ZIOP Guru Trades in Q3 2013

Steven Cohen Sold Out
Chuck Royce 576,000 sh (-12.73%)
Paul Tudor Jones 18,200 sh (-27.49%)
» More
Q4 2013

ZIOP Guru Trades in Q4 2013

Paul Tudor Jones 27,211 sh (+49.51%)
Chuck Royce 366,000 sh (-36.46%)
» More
Q1 2014

ZIOP Guru Trades in Q1 2014

Jim Simons 83,774 sh (New)
Steven Cohen 23,200 sh (New)
Chuck Royce 331,000 sh (-9.56%)
Paul Tudor Jones 19,849 sh (-27.06%)
» More
» Details

Insider Trades

Latest Guru Trades with ZIOP

GuruDate Trades Impact to Portfolio Price Range * (?) Current Price Change from Average Current Shares
Jean-Marie Eveillard 2013-06-30 Sold Out $1.52 - $2.621 $ 3.2475%0
Jean-Marie Eveillard 2013-03-31 New Buy$1.72 - $5.71 $ 3.24-27%200000
Premium More recent guru trades are included for Premium Members only!!
» Interactive Charts

Peter Lynch Chart ( What is Peter Lynch Charts )

Ratios

vs
industry
vs
history
P/B 8.10
ZIOP's P/B is ranked higher than
66% of the 956 Companies
in the Global Biotechnology industry.

( Industry Median: 5.51 vs. ZIOP: 8.10 )
ZIOP' s 10-Year P/B Range
Min: 2.5   Max: 121.3
Current: 8.1

2.5
121.3
P/S 377.30
ZIOP's P/S is ranked higher than
51% of the 956 Companies
in the Global Biotechnology industry.

( Industry Median: 19.16 vs. ZIOP: 377.30 )
ZIOP' s 10-Year P/S Range
Min: 0   Max: 622
Current: 377.3

0
622
EV-to-EBIT -6.08
ZIOP's EV-to-EBIT is ranked higher than
63% of the 956 Companies
in the Global Biotechnology industry.

( Industry Median: 9999.00 vs. ZIOP: -6.08 )
ZIOP' s 10-Year EV-to-EBIT Range
Min: 6.5   Max: 9.4
Current: -6.08

6.5
9.4
Current Ratio 8.43
ZIOP's Current Ratio is ranked higher than
87% of the 892 Companies
in the Global Biotechnology industry.

( Industry Median: 4.02 vs. ZIOP: 8.43 )
ZIOP' s 10-Year Current Ratio Range
Min: 0.1   Max: 32.08
Current: 8.43

0.1
32.08
Quick Ratio 8.43
ZIOP's Quick Ratio is ranked higher than
87% of the 892 Companies
in the Global Biotechnology industry.

( Industry Median: 3.74 vs. ZIOP: 8.43 )
ZIOP' s 10-Year Quick Ratio Range
Min: 0.1   Max: 32.08
Current: 8.43

0.1
32.08

Valuation & Return

vs
industry
vs
history
Price/Net Cash 8.30
ZIOP's Price/Net Cash is ranked higher than
86% of the 956 Companies
in the Global Biotechnology industry.

( Industry Median: 65.19 vs. ZIOP: 8.30 )
ZIOP' s 10-Year Price/Net Cash Range
Min: 2.04   Max: 40.75
Current: 8.3

2.04
40.75
Price/Net Current Asset Value 8.30
ZIOP's Price/Net Current Asset Value is ranked higher than
84% of the 956 Companies
in the Global Biotechnology industry.

( Industry Median: 44.88 vs. ZIOP: 8.30 )
ZIOP' s 10-Year Price/Net Current Asset Value Range
Min: 2.04   Max: 40.75
Current: 8.3

2.04
40.75
Price/Tangible Book 7.90
ZIOP's Price/Tangible Book is ranked higher than
73% of the 956 Companies
in the Global Biotechnology industry.

( Industry Median: 8.78 vs. ZIOP: 7.90 )
ZIOP' s 10-Year Price/Tangible Book Range
Min: 1.81   Max: 98.5
Current: 7.9

1.81
98.5
Forward Rate of Return (Yacktman) -5.28
ZIOP's Forward Rate of Return (Yacktman) is ranked higher than
79% of the 738 Companies
in the Global Biotechnology industry.

( Industry Median: -10.54 vs. ZIOP: -5.28 )
ZIOP' s 10-Year Forward Rate of Return (Yacktman) Range
Min: 48.5   Max: 212.2
Current: -5.28

48.5
212.2

Business Description

Industry: Biotechnology » Biotechnology
Compare:NVO, AMGN, GILD, BIIB, CELG » details
Traded in other countries:WEK.Germany
ZIOPHARM Oncology, Inc. is a Delaware Corporation originally incorporated in Colorado in September 1998 under the name Net Escapes, Inc. and later changed its name to "EasyWeb, Inc." in February 1999. Following reincorporation in Delaware in May 2005 under the same name, we completed a "reverse" acquisition of privately held ZIOPHARM, Inc., a Delaware corporation on September 13, 2005. It is a biopharmaceutical company engaged in the development and commercialization of small molecule and synthetic biology approaches to new cancer therapies. Palifosfamide (Zymafos or ZIO-201) is a novel DNA cross-linker that in preclinical study has been shown to bypass resistance mediated by aldehyde dehydrogenase (ALDH), in addition to conferring a favorable toxicity profile compared to other in-class agents. Palifosfamide, administered intravenously, is currently in a randomized, double-blinded, placebo-controlled Phase 3 trial for the treatment of metastatic soft tissue sarcoma in the front-line setting. The Company is also currently completing a Phase 1 study of palifosfamide in combination with standard of care for addressing small cell lung cancer; an investigational new drug application has been accepted for the oral form of palifosfamide. DNA-based therapeutics (synthetic biology), in partnership with Intrexon Corporation, include two clinical-stage product candidates, both of which are DNA IL-12 using the RheoSwitch Therapeutic System to be turned on/off by an oral activator ligand and are currently in Phase 1. Additionally, multiple INDs are expected in the next 12-24 months resulting from preclinical and discovery work underway to advance multiple antibody, immunotoxin, and protein decoy candidates, systemic delivery and a next generation RheoSwitch Therapeutic System. Indibulin (Zybulin or ZIO-301) is a novel, oral tubulin binding agent that is expected to have several potential benefits including oral dosing, application in multi-drug resistant tumors, no neuropathy and a quite tolerable toxicity profile. It is currently being studied in Phase 1/2 in metastatic breast cancer. Darinaparsin (Zinapar or ZIO-101) is a novel mitochondrial- and hedgehog-targeted agent (organic arsenic) currently in a solid tumor Phase 1 study with oral administration and has been developed intravenously for the treatment of relapsed peripheral T-cell lymphoma. ZIOPHARM's operations are located in Boston, MA, Germantown, MD and New York City.
» More Articles for ZIOP

Headlines

Articles On GuruFocus.com
Hayman Advisors Update - Second Quarter Sells and Company Results Aug 26 2013 
Bass’ New Buy – ZIOPHARM Oncology Inc. May 16 2013 
The Far-Off Four, 52-week Lows Held by Gurus May 11 2013 
comment on ZIOP Mar 15 2013 
cooldecency99 note on ZIOP May 01 2010 
ZIOPHARM Reports Second Quarter Financial Results and Updates Clinical Programs Aug 14 2009 


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