| RETA | | Reata Pharmaceuticals Inc | Biotechnology | 4,281.92 | 574,907 | 117,528.24 | New Holding | 0.25 | +0.25% | 1.73 | -35.94% | -36.97% |
| ASND | | Ascendis Pharma A/S | Biotechnology | 5,374.88 | 603,093 | 83,902.30 | New Holding | 0.18 | +0.18% | 1.26 | -18.33% | -19.49% |
| SRPT | | Sarepta Therapeutics Inc | Biotechnology | 7,281.46 | 463,410 | 59,798.43 | New Holding | 0.13 | +0.13% | 0.60 | -27.86% | -27.45% |
| BSP:GNDI3 | | Notre Dame Intermedica Participacoes SA | Healthcare Plans | 22,536.43 | 1,550,250 | 26,376.54 | New Holding | 0.06 | +0.06% | 0.26 | -47.77% | -44.14% |
| QGEN | | Qiagen NV | Medical Diagnostics & Research | 9,176.75 | 6,100,700 | 207,871.99 | +196.68% | 0.45 | +0.30% | 2.68 | +18.58% | +19.14% |
| CNC | | Centene Corp | Healthcare Plans | 32,039.87 | 8,635,100 | 542,888.74 | +88.75% | 1.16 | +0.55% | 1.47 | -10.73% | -13.15% |
| NVST | | Envista Holdings Corp | Medical Devices & Instruments | 2,061.91 | 1,869,611 | 55,415.27 | +86.96% | 0.12 | +0.06% | 1.18 | -57.40% | -56.21% |
| BLUE | | bluebird bio Inc | Biotechnology | 2,329.01 | 4,604,667 | 404,059.53 | +63.54% | 0.87 | +0.34% | 8.28 | -51.83% | -52.27% |
| ARGX | | argenx SE | Biotechnology | 5,652.99 | 1,418,173 | 228,101.28 | +57.40% | 0.49 | +0.18% | 3.31 | -16.69% | -17.70% |
| TSE:4568 | | Daiichi Sankyo Co Ltd | Drug Manufacturers | 4,385,549.43 | 7,002,630 | 462,483.63 | +52.98% | 0.99 | +0.34% | 1.08 | -5.87% | -5.87% |
| TSE:4503 | | Astellas Pharma Inc | Drug Manufacturers | 2,998,938.80 | 27,040,300 | 461,577.58 | +44.44% | 0.99 | +0.30% | 1.45 | -12.73% | -12.73% |
| MOH | | Molina Healthcare Inc | Healthcare Plans | 8,039.63 | 1,063,057 | 144,246.20 | +39.36% | 0.31 | +0.09% | 1.75 | -0.31% | -2.62% |
| TFX | | Teleflex Inc | Medical Devices & Instruments | 13,650.15 | 269,500 | 101,450.58 | +35.70% | 0.22 | +0.06% | 0.58 | -21.33% | -21.71% |
| AGIO | | Agios Pharmaceuticals Inc | Biotechnology | 2,568.57 | 6,435,516 | 307,295.89 | +24.28% | 0.66 | +0.13% | 9.39 | -20.72% | -21.49% |
| LSE:NMC | | NMC Health PLC | Healthcare Providers & Services | 1,958.48 | 3,025,119 | 70,877.13 | +17.49% | 0.15 | +0.02% | 1.45 | -46.38% | -46.89% |
| BIIB | | Biogen Inc | Drug Manufacturers | 52,307.98 | 3,151,603 | 935,175.16 | +15.93% | 2 | +0.27% | 1.81 | +3.32% | +1.27% |
| ELAN | | Elanco Animal Health Inc | Drug Manufacturers | 8,046.37 | 15,241,486 | 448,861.76 | +14.49% | 0.96 | +0.12% | 3.82 | -30.62% | -31.44% |
| TSE:4543 | | Terumo Corp | Medical Devices & Instruments | 2,639,009.87 | 4,077,000 | 144,628.82 | +13.29% | 0.31 | +0.04% | 0.55 | -8.21% | -8.21% |
| XAMS:PHIA | | Royal Philips NV | Medical Diagnostics & Research | 32,106.24 | 8,817,651 | 431,041.43 | +12.19% | 0.92 | +0.10% | 0.99 | -17.67% | -17.20% |
| LSE:SN. | | Smith & Nephew PLC | Medical Devices & Instruments | 11,922.22 | 13,277,551 | 320,000.86 | +7.97% | 0.69 | +0.05% | 1.52 | -25.19% | -24.60% |
