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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
LEFKOFF KYLEDirector2017-09-29Sell38,86557,720$12.31478.43-7.8812,720 (Direct)
45,000 (See footnote))
VAN LUNSEN GIL JDirector2017-09-29Sell39,92815,332$12.36493.51-8.2515,332 (Direct)
LEFKOFF KYLEDirector2017-03-31Sell45,00051,585$8.92401.427.136,585 (Direct)
45,000 (See footnote(F2,))
BAUM CHARLES MDirector2017-03-28Sell25,0005,000$9.27231.7522.335,000 (Direct)
Redmile Group, LLC10% Owner2016-09-28Sell2,492,57816,658,072$6.3615852.878.3
16,658,072 (See Footnote(F2,))
Redmile Group, LLC10% Owner2016-09-15Sell400,00019,150,650$3.51400224
19,150,650 (See footnote(F5,))
Redmile Group, LLC10% Owner2016-09-15Buy400,00019,150,650$3.511404223.08
19,150,650 (See footnote(F5,))
Redmile Group, LLC10% Owner2016-01-20Buy300,00019,150,650$3.19957255.49
19,150,650 (See footnote)
Redmile Group, LLC10% Owner2016-01-12Buy75,00018,850,650$3.6270215
18,850,650 (See Footnote)
Redmile Group, LLC10% Owner2016-01-11Buy925,00018,775,650$3.673394.75208.99
18,775,650 (See footnote)
Redmile Group, LLC10% Owner2015-10-01Buy600,14017,850,650$4.582748.64147.6
17,850,650 (See footnote)
Redmile Group, LLC10% Owner2015-10-01Buy782,59218,033,102$4.583584.27147.6
18,033,102 (See footnote)
Redmile Group, LLC10% Owner2015-08-26Buy49,90017,250,510$5.48273.45106.93
17,250,510 (See footnote)
Redmile Group, LLC10% Owner2015-08-25Buy790,00017,200,610$5.384250.2110.78
17,200,610 (See Footnote)
Redmile Group, LLC10% Owner2015-08-12Buy532,50032,616,220$5.883131.192.86
16,205,610 (See footnote)
16,410,610 (See Footnote)
Redmile Group, LLC10% Owner2015-08-10Buy1,048,99315,878,110$5.86084.1695.52
15,878,110 (See footnote)
BAUM CHARLES MDirector2015-05-08Sell25,0000$7.38184.553.66Link
LEFKOFF KYLEDirector2015-03-03Sell70,00048,585$856041.753,585 (Direct)
45,000 (See footnote)
Robbins Andrews RSVP, Commercial Operations2015-03-02Sell21,5760$8.2517837.45Link
Squarer RonCEO
(Click for the stocks that their CEOs have bought)
2015-03-02Sell40,00012,927$8.2533037.4512,927 (Direct)
MOORE JOHN RVP, General Counsel2013-11-29Sell11,66620$5.7967.5595.8520 (Direct)
MOORE JOHN RVP, General Counsel2013-11-13Sell20011,686$5.791.1695.8511,686 (Direct)
Ratcliffe LiamDirector2013-09-27Sell1,125,7280$66754.3789
0 (See footnote)
Ratcliffe LiamDirector2013-09-16Sell1,673,1721,125,728$6.0810172.8986.51
1,125,728 (See footnote)
Ratcliffe LiamDirector2013-09-06Sell577,2862,798,900$5.793342.4995.85
2,798,900 (See footnote)
MOORE JOHN RVP, General Counsel2013-08-02Sell75,38411,886$7.02529.261.5411,886 (Direct)
MOORE JOHN RVP, General Counsel2013-07-23Sell5,00016,645$6.532.574.4616,645 (Direct)
MOORE JOHN RVP, General Counsel2012-10-08Sell28,54711,886$5.69162.4399.311,886 (Direct)
0 (Held by spouse)
CARRUTHERS MICHAELCFO2012-02-10Sell1,54594,570$2.654.09327.9294,570 (Direct)
CARRUTHERS MICHAELCFO2012-01-12Sell1,99496,115$2.064.11450.4996,115 (Direct)
CARRUTHERS MICHAELCFO2011-12-12Sell1,74396,295$2.354.1382.5596,295 (Direct)
BVF PARTNERS L P/IL10% Owner2011-12-05Buy183,8535,938,900$2.11387.93437.44
4,893,000 (See Explanation of Responses)
1,045,900 (See Explanation of Respones)
CARRUTHERS MICHAELCFO2011-11-11Sell1,65698,038$2.474.09359.1198,038 (Direct)
CARRUTHERS MICHAELCFO2011-10-12Sell1,97799,694$2.084.11445.1999,694 (Direct)
CARRUTHERS MICHAELCFO2011-09-12Sell2,03476,978$2.024.11461.3976,978 (Direct)
CARUTHERS MARVIN HDirector2011-08-16Sell2,300446,934$2.144.92429.91177,763 (Direct)
269,040 (Held by GRAT)
131 (Held in Family LLC; disclaimed by Reporting Person)
CARRUTHERS MICHAELCFO2011-08-12Sell1,81079,012$2.264.09401.7779,012 (Direct)
LEFKOFF KYLEDirector2011-08-11Buy5,00049,585$2.2211.1410.8110,000 (Direct)
15,000 (In 401k Profit Sharing Plan)
24,585 (Held as custodian for UTMA for benefit of minor children)
CARRUTHERS MICHAELCFO2011-07-12Sell1,63880,822$2.54.1353.680,822 (Direct)
CONWAY ROBERTCEO2011-06-17Buy25,000656,196$2.1754.25422.58576,196 (Direct)
80,000 (Held by spouse as custodian for UTMA for benefit of minor children)
CARRUTHERS MICHAELCFO2011-06-10Sell1,72082,460$2.384.09376.4782,460 (Direct)
CONWAY ROBERTCEO2011-05-13Buy20,000631,196$2.8657.2296.5551,196 (Direct)
80,000 (Held by spouse as custodian for UTMA for benefit of minor children)
CARRUTHERS MICHAELCFO2011-05-12Sell1,48484,180$2.754.08312.3684,180 (Direct)
CARRUTHERS MICHAELCFO2011-04-12Sell1,3400$3.044.07273.03Link
MOORE JOHN RVP, General Counsel2011-04-05Sell3560$3.31.17243.64Link
CARRUTHERS MICHAELCFO2011-03-11Sell1,3100$3.114.07264.63Link
CARRUTHERS MICHAELCFO2011-02-11Sell1,4030$2.914.08289.69Link
CARRUTHERS MICHAELCFO2011-01-12Sell1,27289,717$3.24.07254.38Link
MOORE JOHN RVP, General Counsel2011-01-11Sell2,959356$3.39.76243.64Link
MOORE JOHN RVP, General Counsel2011-01-06Sell24,0393,315$3.2578.13248.92Link
CARRUTHERS MICHAELCFO2010-12-10Sell1,25689,650$3.244.07250Link
LEFKOFF KYLEDirector2010-11-18Sell10,00044,585$3.2732.7246.79Link
CARRUTHERS MICHAELCFO2010-11-12Sell1,22090,906$3.334.06240.54Link
CARRUTHERS MICHAELCFO2010-10-12Sell1,22592,126$3.324.07241.57Link
MOORE JOHN RVP, General Counsel2010-10-05Sell20,06727,354$3.2966.02244.68Link
CARRUTHERS MICHAELCFO2010-09-14Sell1,41570,353$2.884.08293.75Link
CARRUTHERS MICHAELCFO2010-08-23Sell1771,768$2.790.05306.45Link
MOORE JOHN RVP, General Counsel2010-08-03Sell6,31921,317$3.2520.54248.92Link
CARRUTHERS MICHAELCFO2010-07-23Sell1,30971,785$3.114.07264.63Link
CARRUTHERS MICHAELCFO2010-06-23Sell1,20873,094$3.374.07236.5Link
CARUTHERS MARVIN HDirector2010-06-08Sell1,650449,234$3.125.15263.46Link
CARRUTHERS MICHAELCFO2010-05-21Sell1,18374,302$3.444.07229.65Link
LEFKOFF KYLEDirector2010-05-07Buy4,00054,585$3.7114.84205.66Link
CARRUTHERS MICHAELCFO2010-04-23Sell1,07475,485$3.784.06200Link
CARRUTHERS MICHAELCFO2010-03-23Sell1,66176,559$2.464.09360.98Link
CARRUTHERS MICHAELCFO2010-02-23Sell1,70778,220$2.44.1372.5Link
CARRUTHERS MICHAELCFO2010-02-05Sell6,28679,927$2.4415.34364.75Link
CARRUTHERS MICHAELCFO2010-01-22Sell1,64486,213$2.494.09355.42Link
CARRUTHERS MICHAELCFO2010-01-06Sell5,68186,706$2.6915.28321.56Link
CARRUTHERS MICHAELCFO2009-12-23Sell1,53394,432$2.664.08326.32Link
CARRUTHERS MICHAELCFO2009-11-23Sell2,04593,920$2.014.11464.18Link
CARRUTHERS MICHAELCFO2009-10-23Sell2,04995,965$2.014.12464.18Link
CARRUTHERS MICHAELCFO2009-09-25Sell1,31579,308$2.773.64309.39Link
CARRUTHERS MICHAELCFO2009-08-24Sell88280,623$4.173.68171.94Link
CARRUTHERS MICHAELCFO2009-07-30Sell92580,738$3.953.65187.09Link
CARRUTHERS MICHAELCFO2009-06-22Sell1,17081,663$3.063.58270.59
CARRUTHERS MICHAELCFO2009-05-26Sell1,17082,833$3.133.66262.3
LEFKOFF KYLEDirector2008-11-13Buy3,0006,000$3.289.84245.73
LEFKOFF KYLEDirector2008-03-10Buy3,0003,000$5.3916.17110.39
WILLIAMS DOUGLAS EDirector2008-03-06Buy2,5002,500$6.1615.484.09
ZABRISKIE JOHN LDirector2008-03-05Buy30,00030,000$6.37191.178.02
CARRUTHERS MICHAELCFO2007-09-19Sell10,00040,812$13130-12.77
VAN LUNSEN GIL JDirector2007-08-09Sell12,0005,260$11.47137.64-1.13
KOCH KEVINPresident & CSO2007-02-05Sell20,000555,354$14.05281-19.29
KOCH KEVINPresident & CSO2007-01-19Sell26,900575,354$14376.6-19
MOORE JOHN RVP, General Counsel2006-11-20Sell27,2630$13.04355.51-13.04
CONWAY ROBERTCEO2006-11-15Sell50,000243,241$12.5625-9.28
CARRUTHERS MICHAELCFO2006-11-13Sell14,87030,449$11.98178.14-5.34
LEFKOFF KYLEDirector2006-11-09Sell51,0001,000$11.7596.7-3.08
CARRUTHERS MICHAELCFO2006-11-08Sell10,00045,319$10.85108.54.52
CONWAY ROBERTCEO2006-11-03Sell100,000193,241$10.01100113.29
CARRUTHERS MICHAELCFO2006-10-27Sell5,00055,319$9.9549.7513.97
CARRUTHERS MICHAELCFO2006-03-07Sell5,00060,449$9.4947.4519.49Link
LEFKOFF KYLEDirector2006-02-21Sell11,00089,135$9.0299.2225.72Link
KOCH KEVINPresident & CSO2006-02-17Sell20,000744,540$9.38187.620.9Link
MOORE JOHN RVP, General Counsel2006-02-17Sell4,4562,252$9.3841.820.9Link
CARRUTHERS MICHAELCFO2006-02-17Sell10,00065,449$8.7487.429.75Link
CARRUTHERS MICHAELCFO2006-02-13Sell8,90975,449$8.1672.738.97Link
CARRUTHERS MICHAELCHIEF FINANCIAL OFFICER2005-06-17Sell5,00084,243$6.1530.7584.39Link
CARRUTHERS MICHAELCHIEF FINANCIAL OFFICER2005-03-31Sell5,00084,072$6.9234.663.87Link
VAN LUNSEN GIL JDirector2005-03-24Buy1,3153,260$7.479.8251.81Link
PISCOPIO TONYVice President, Chemistry2004-04-29Sell5,000553,527$11.4757.35-1.13Link
PISCOPIO TONYVice President, Chemistry2004-04-28Sell5,000558,527$10.9554.753.56Link
PISCOPIO TONYVP/Dir of Chemistry2004-04-27Sell29,500563,527$6.7197.6569.25Link
PISCOPIO TONYVP Chem,Dir Proc. Chem2004-04-23Sell10,000593,027$9.0990.924.75Link
PISCOPIO TONYVice President, Chemistry2004-04-21Sell5,000603,027$9.1545.7523.93Link
PISCOPIO TONYVice President, Chemistry2004-04-20Sell5,000608,027$94526Link
PISCOPIO TONYVice President, Chemistry2004-04-19Sell5,000613,027$8.6443.231.25Link
PISCOPIO TONYVice President, Chemistry2004-04-16Sell5,000618,027$8.5842.932.17Link
PISCOPIO TONYVice President, Chemistry2004-04-15Sell5,000623,027$8.6843.430.65Link
PISCOPIO TONYVice President, Chemistry2004-04-14Sell5,000628,027$8.3441.735.97Link
PISCOPIO TONYVice President, Chemistry2004-04-13Sell5,000633,027$8.7543.7529.6Link
PISCOPIO TONYVice President, Chemistry2004-04-12Sell5,000638,027$8.4642.334.04Link
PISCOPIO TONYVice President, Chemistry2004-04-08Sell5,000643,027$94526Link
PISCOPIO TONYVice President, Chemistry2004-04-07Sell5,000648,027$9.145.524.62Link
PISCOPIO TONYVice President, Chemistry2004-04-06Sell5,000653,027$9.3546.7521.28Link
PISCOPIO TONYVice President, Chemistry2004-04-05Sell5,000658,027$8.8644.327.99Link
PISCOPIO TONYVP of Chemistry2004-04-02Sell10,000663,027$8.9689.626.56Link
CARRUTHERS MICHAELCHIEF FINANCIAL OFFICER2004-02-26Sell14,00088,973$7.51105.1451Link
VAN LUNSEN GIL JDirector2003-11-10Buy5801,945$52.9126.8Link
BVF PARTNERS L P/IL2003-11-05Sell3,865,0350$519325.18126.8Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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