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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
LEFKOFF KYLEDirector2017-03-31Sell45,00051,585$8.92401.4-7.296,585 (Direct)
45,000 (See footnote(F2,))
BAUM CHARLES MDirector2017-03-28Sell25,0005,000$9.27231.75-10.795,000 (Direct)
Redmile Group, LLC10% Owner2016-09-28Sell2,492,57816,658,072$6.3615852.830.03
16,658,072 (See Footnote(F2,))
Redmile Group, LLC10% Owner2016-09-15Sell400,00019,150,650$3.51400136.29
19,150,650 (See footnote(F5,))
Redmile Group, LLC10% Owner2016-09-15Buy400,00019,150,650$3.511404135.61
19,150,650 (See footnote(F5,))
Redmile Group, LLC10% Owner2016-01-20Buy300,00019,150,650$3.19957159.25
19,150,650 (See footnote)
Redmile Group, LLC10% Owner2016-01-12Buy75,00018,850,650$3.6270129.72
18,850,650 (See Footnote)
Redmile Group, LLC10% Owner2016-01-11Buy925,00018,775,650$3.673394.75125.34
18,775,650 (See footnote)
Redmile Group, LLC10% Owner2015-10-01Buy600,14017,850,650$4.582748.6480.57
17,850,650 (See footnote)
Redmile Group, LLC10% Owner2015-10-01Buy782,59218,033,102$4.583584.2780.57
18,033,102 (See footnote)
Redmile Group, LLC10% Owner2015-08-26Buy49,90017,250,510$5.48273.4550.91
17,250,510 (See footnote)
Redmile Group, LLC10% Owner2015-08-25Buy790,00017,200,610$5.384250.253.72
17,200,610 (See Footnote)
Redmile Group, LLC10% Owner2015-08-12Buy532,50032,616,220$5.883131.140.65
16,205,610 (See footnote)
16,410,610 (See Footnote)
Redmile Group, LLC10% Owner2015-08-10Buy1,048,99315,878,110$5.86084.1642.59
15,878,110 (See footnote)
BAUM CHARLES MDirector2015-05-08Sell25,0000$7.38184.512.06Link
LEFKOFF KYLEDirector2015-03-03Sell70,00048,585$85603.383,585 (Direct)
45,000 (See footnote)
Robbins Andrews RSVP, Commercial Operations2015-03-02Sell21,5760$8.251780.24Link
Squarer RonCEO
(Click for the stocks that their CEOs have bought)
2015-03-02Sell40,00012,927$8.253300.2412,927 (Direct)
MOORE JOHN RVP, General Counsel2013-11-29Sell11,66620$5.7967.5542.8320 (Direct)
MOORE JOHN RVP, General Counsel2013-11-13Sell20011,686$5.791.1642.8311,686 (Direct)
Ratcliffe LiamDirector2013-09-27Sell1,125,7280$66754.3737.83
0 (See footnote)
Ratcliffe LiamDirector2013-09-16Sell1,673,1721,125,728$6.0810172.8936.02
1,125,728 (See footnote)
Ratcliffe LiamDirector2013-09-06Sell577,2862,798,900$5.793342.4942.83
2,798,900 (See footnote)
MOORE JOHN RVP, General Counsel2013-08-02Sell75,38411,886$7.02529.217.8111,886 (Direct)
MOORE JOHN RVP, General Counsel2013-07-23Sell5,00016,645$6.532.527.2316,645 (Direct)
MOORE JOHN RVP, General Counsel2012-10-08Sell28,54711,886$5.69162.4345.3411,886 (Direct)
0 (Held by spouse)
CARRUTHERS MICHAELCFO2012-02-10Sell1,54594,570$2.654.09212.0894,570 (Direct)
CARRUTHERS MICHAELCFO2012-01-12Sell1,99496,115$2.064.11301.4696,115 (Direct)
CARRUTHERS MICHAELCFO2011-12-12Sell1,74396,295$2.354.1251.9196,295 (Direct)
BVF PARTNERS L P/IL10% Owner2011-12-05Buy183,8535,938,900$2.11387.93291.94
4,893,000 (See Explanation of Responses)
1,045,900 (See Explanation of Respones)
CARRUTHERS MICHAELCFO2011-11-11Sell1,65698,038$2.474.09234.8298,038 (Direct)
CARRUTHERS MICHAELCFO2011-10-12Sell1,97799,694$2.084.11297.699,694 (Direct)
CARRUTHERS MICHAELCFO2011-09-12Sell2,03476,978$2.024.11309.4176,978 (Direct)
CARUTHERS MARVIN HDirector2011-08-16Sell2,300446,934$2.144.92286.45177,763 (Direct)
269,040 (Held by GRAT)
131 (Held in Family LLC; disclaimed by Reporting Person)
CARRUTHERS MICHAELCFO2011-08-12Sell1,81079,012$2.264.09265.9379,012 (Direct)
LEFKOFF KYLEDirector2011-08-11Buy5,00049,585$2.2211.1272.5210,000 (Direct)
15,000 (In 401k Profit Sharing Plan)
24,585 (Held as custodian for UTMA for benefit of minor children)
CARRUTHERS MICHAELCFO2011-07-12Sell1,63880,822$2.54.1230.880,822 (Direct)
CONWAY ROBERTCEO2011-06-17Buy25,000656,196$2.1754.25281.11576,196 (Direct)
80,000 (Held by spouse as custodian for UTMA for benefit of minor children)
CARRUTHERS MICHAELCFO2011-06-10Sell1,72082,460$2.384.09247.4882,460 (Direct)
CONWAY ROBERTCEO2011-05-13Buy20,000631,196$2.8657.2189.16551,196 (Direct)
80,000 (Held by spouse as custodian for UTMA for benefit of minor children)
CARRUTHERS MICHAELCFO2011-05-12Sell1,48484,180$2.754.08200.7384,180 (Direct)
CARRUTHERS MICHAELCFO2011-04-12Sell1,3400$3.044.07172.04Link
MOORE JOHN RVP, General Counsel2011-04-05Sell3560$3.31.17150.61Link
CARRUTHERS MICHAELCFO2011-03-11Sell1,3100$3.114.07165.92Link
CARRUTHERS MICHAELCFO2011-02-11Sell1,4030$2.914.08184.19Link
CARRUTHERS MICHAELCFO2011-01-12Sell1,27289,717$3.24.07158.44Link
MOORE JOHN RVP, General Counsel2011-01-11Sell2,959356$3.39.76150.61Link
MOORE JOHN RVP, General Counsel2011-01-06Sell24,0393,315$3.2578.13154.46Link
CARRUTHERS MICHAELCFO2010-12-10Sell1,25689,650$3.244.07155.25Link
LEFKOFF KYLEDirector2010-11-18Sell10,00044,585$3.2732.7152.91Link
CARRUTHERS MICHAELCFO2010-11-12Sell1,22090,906$3.334.06148.35Link
CARRUTHERS MICHAELCFO2010-10-12Sell1,22592,126$3.324.07149.1Link
MOORE JOHN RVP, General Counsel2010-10-05Sell20,06727,354$3.2966.02151.37Link
CARRUTHERS MICHAELCFO2010-09-14Sell1,41570,353$2.884.08187.15Link
CARRUTHERS MICHAELCFO2010-08-23Sell1771,768$2.790.05196.42Link
MOORE JOHN RVP, General Counsel2010-08-03Sell6,31921,317$3.2520.54154.46Link
CARRUTHERS MICHAELCFO2010-07-23Sell1,30971,785$3.114.07165.92Link
CARRUTHERS MICHAELCFO2010-06-23Sell1,20873,094$3.374.07145.4Link
CARUTHERS MARVIN HDirector2010-06-08Sell1,650449,234$3.125.15165.06Link
CARRUTHERS MICHAELCFO2010-05-21Sell1,18374,302$3.444.07140.41Link
LEFKOFF KYLEDirector2010-05-07Buy4,00054,585$3.7114.84122.91Link
CARRUTHERS MICHAELCFO2010-04-23Sell1,07475,485$3.784.06118.78Link
CARRUTHERS MICHAELCFO2010-03-23Sell1,66176,559$2.464.09236.18Link
CARRUTHERS MICHAELCFO2010-02-23Sell1,70778,220$2.44.1244.58Link
CARRUTHERS MICHAELCFO2010-02-05Sell6,28679,927$2.4415.34238.93Link
CARRUTHERS MICHAELCFO2010-01-22Sell1,64486,213$2.494.09232.13Link
CARRUTHERS MICHAELCFO2010-01-06Sell5,68186,706$2.6915.28207.43Link
CARRUTHERS MICHAELCFO2009-12-23Sell1,53394,432$2.664.08210.9Link
CARRUTHERS MICHAELCFO2009-11-23Sell2,04593,920$2.014.11311.44Link
CARRUTHERS MICHAELCFO2009-10-23Sell2,04995,965$2.014.12311.44Link
CARRUTHERS MICHAELCFO2009-09-25Sell1,31579,308$2.773.64198.56Link
CARRUTHERS MICHAELCFO2009-08-24Sell88280,623$4.173.6898.32Link
CARRUTHERS MICHAELCFO2009-07-30Sell92580,738$3.953.65109.37Link
CARRUTHERS MICHAELCFO2009-06-22Sell1,17081,663$3.063.58170.26
CARRUTHERS MICHAELCFO2009-05-26Sell1,17082,833$3.133.66164.22
LEFKOFF KYLEDirector2008-11-13Buy3,0006,000$3.289.84152.13
LEFKOFF KYLEDirector2008-03-10Buy3,0003,000$5.3916.1753.43
WILLIAMS DOUGLAS EDirector2008-03-06Buy2,5002,500$6.1615.434.25
ZABRISKIE JOHN LDirector2008-03-05Buy30,00030,000$6.37191.129.83
CARRUTHERS MICHAELCFO2007-09-19Sell10,00040,812$13130-36.38
VAN LUNSEN GIL JDirector2007-08-09Sell12,0005,260$11.47137.64-27.9
KOCH KEVINPresident & CSO2007-02-05Sell20,000555,354$14.05281-41.14
KOCH KEVINPresident & CSO2007-01-19Sell26,900575,354$14376.6-40.93
MOORE JOHN RVP, General Counsel2006-11-20Sell27,2630$13.04355.51-36.58
CONWAY ROBERTCEO2006-11-15Sell50,000243,241$12.5625-33.84
CARRUTHERS MICHAELCFO2006-11-13Sell14,87030,449$11.98178.14-30.97
LEFKOFF KYLEDirector2006-11-09Sell51,0001,000$11.7596.7-29.32
CARRUTHERS MICHAELCFO2006-11-08Sell10,00045,319$10.85108.5-23.78
CONWAY ROBERTCEO2006-11-03Sell100,000193,241$10.011001-17.38
CARRUTHERS MICHAELCFO2006-10-27Sell5,00055,319$9.9549.75-16.88
CARRUTHERS MICHAELCFO2006-03-07Sell5,00060,449$9.4947.45-12.86Link
LEFKOFF KYLEDirector2006-02-21Sell11,00089,135$9.0299.22-8.31Link
KOCH KEVINPresident & CSO2006-02-17Sell20,000744,540$9.38187.6-11.83Link
MOORE JOHN RVP, General Counsel2006-02-17Sell4,4562,252$9.3841.8-11.83Link
CARRUTHERS MICHAELCFO2006-02-17Sell10,00065,449$8.7487.4-5.38Link
CARRUTHERS MICHAELCFO2006-02-13Sell8,90975,449$8.1672.71.35Link
CARRUTHERS MICHAELCHIEF FINANCIAL OFFICER2005-06-17Sell5,00084,243$6.1530.7534.47Link
CARRUTHERS MICHAELCHIEF FINANCIAL OFFICER2005-03-31Sell5,00084,072$6.9234.619.51Link
VAN LUNSEN GIL JDirector2005-03-24Buy1,3153,260$7.479.8210.71Link
PISCOPIO TONYVice President, Chemistry2004-04-29Sell5,000553,527$11.4757.35-27.9Link
PISCOPIO TONYVice President, Chemistry2004-04-28Sell5,000558,527$10.9554.75-24.47Link
PISCOPIO TONYVP/Dir of Chemistry2004-04-27Sell29,500563,527$6.7197.6523.43Link
PISCOPIO TONYVP Chem,Dir Proc. Chem2004-04-23Sell10,000593,027$9.0990.9-9.02Link
PISCOPIO TONYVice President, Chemistry2004-04-21Sell5,000603,027$9.1545.75-9.62Link
PISCOPIO TONYVice President, Chemistry2004-04-20Sell5,000608,027$945-8.11Link
PISCOPIO TONYVice President, Chemistry2004-04-19Sell5,000613,027$8.6443.2-4.28Link
PISCOPIO TONYVice President, Chemistry2004-04-16Sell5,000618,027$8.5842.9-3.61Link
PISCOPIO TONYVice President, Chemistry2004-04-15Sell5,000623,027$8.6843.4-4.72Link
PISCOPIO TONYVice President, Chemistry2004-04-14Sell5,000628,027$8.3441.7-0.84Link
PISCOPIO TONYVice President, Chemistry2004-04-13Sell5,000633,027$8.7543.75-5.49Link
PISCOPIO TONYVice President, Chemistry2004-04-12Sell5,000638,027$8.4642.3-2.25Link
PISCOPIO TONYVice President, Chemistry2004-04-08Sell5,000643,027$945-8.11Link
PISCOPIO TONYVice President, Chemistry2004-04-07Sell5,000648,027$9.145.5-9.12Link
PISCOPIO TONYVice President, Chemistry2004-04-06Sell5,000653,027$9.3546.75-11.55Link
PISCOPIO TONYVice President, Chemistry2004-04-05Sell5,000658,027$8.8644.3-6.66Link
PISCOPIO TONYVP of Chemistry2004-04-02Sell10,000663,027$8.9689.6-7.7Link
CARRUTHERS MICHAELCHIEF FINANCIAL OFFICER2004-02-26Sell14,00088,973$7.51105.1410.12Link
VAN LUNSEN GIL JDirector2003-11-10Buy5801,945$52.965.4Link
BVF PARTNERS L P/IL2003-11-05Sell3,865,0350$519325.1865.4Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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