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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Popovits Kimberly JPresident and CEO
(Click for the stocks that their CEOs have bought)
2017-09-14Sell5,000307,567$31155-0.0641,132 (Direct)
12,298 (Held by Morgan Stanley as Custodian for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
237,312 (Held by the Popovits 2010 Trust)
Cole G BradleyCOO2017-09-12Sell5,00039,935$31.86159.3-2.7639,935 (Direct)
Popovits Kimberly JPresident and CEO2017-08-14Sell5,000307,567$30.22151.12.5179,057 (Direct)
12,298 (Held by Morgan Stanley as Custodian for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
199,387 (Held by the Popovits 2010 Trust)
Cole G BradleyCOO2017-08-08Sell5,00039,935$30.57152.851.3439,935 (Direct)
Vaughn James JChief Commercial Officer2017-08-08Sell8,00029,785$30.59244.721.2729,785 (Direct)
Febbo Phillip G.Chief Medical Officer2017-07-19Sell3,17417,800$33.57106.55-7.7217,800 (Direct)
Cole G BradleyCOO2017-07-11Sell5,00039,935$32.53162.65-4.7639,935 (Direct)
Popovits Kimberly JPresident and CEO2017-07-05Sell5,000307,567$32.59162.95-4.9479,057 (Direct)
12,298 (Held by Morgan Stanley as Custodian for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
199,387 (Held by the Popovits 2010 Trust)
Shak StevenChief Scientific Officer2017-06-23Sell5,000331,924$33.27166.35-6.88331,924 (Direct)
Cole G BradleyCOO2017-06-13Sell5,00039,935$31.67158.35-2.1839,935 (Direct)
Popovits Kimberly JPresident and CEO2017-06-05Sell5,000307,567$32.32161.6-4.1579,057 (Direct)
199,387 (Held by the Popovits 2010 Trust)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
12,298 (Held by Morgan Stanley as Custodian for Benefit of Kimberly Popovits)
Shak StevenChief Scientific Officer2017-05-23Sell5,000331,103$29.41475.37331,103 (Direct)
Cohen Fred EDirector2017-05-19Sell8,25071,963$29.54243.714.8765,895 (Direct)
6,068 (By the Jane K Cohen Trust)
Cohen Fred EDirector2017-05-18Sell16,50071,963$29.88493.023.6865,895 (Direct)
6,068 (By the Jane K Cohen Trust)
Cohen Fred EDirector2017-05-16Sell8,25071,963$30.68253.110.9865,895 (Direct)
6,068 (By the Jane K Cohen Trust)
Popovits Kimberly JPresident and CEO2017-05-03Sell5,000306,846$31.77158.85-2.4978,236 (Direct)
12,298 (Held by Morgan Stanley as Custodian for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
199,487 (Held by the Popovits 2010 Trust)
Shak StevenChief Scientific Officer2017-04-24Sell5,000331,103$31.46157.3-1.53331,103 (Direct)
Popovits Kimberly JPresident and CEO2017-04-03Sell5,000306,846$31.3156.5-1.0278,236 (Direct)
199,487 (Held by the Popovits 2010 Trust)
12,298 (Held by Morgan Stanley as Custodian for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
Shak StevenChief Scientific Officer2017-03-23Sell5,000331,103$31.26156.3-0.9331,103 (Direct)
Leber LauraChief Communication Officer2017-03-20Sell3,07214,627$31.8897.94-2.8214,627 (Direct)
Cole G BradleyCOO2017-03-08Sell5,71039,528$31.55180.15-1.8139,528 (Direct)
Popovits Kimberly JPresident and CEO2017-03-06Sell5,000308,210$31.09155.45-0.3578,236 (Direct)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
200,851 (Held by the Popovits 2010 Trust)
Shak StevenChief Scientific Officer2017-02-23Sell5,000331,103$29.36146.85.52331,103 (Direct)
Febbo Phillip G.Chief Medical Officer2017-02-16Sell2,49520,644$30.0975.072.9620,644 (Direct)
Cole G BradleyCOO2017-02-15Sell5,00039,728$291456.8339,728 (Direct)
Shak StevenChief Scientific Officer2017-01-23Sell5,000327,207$27.28136.413.56327,207 (Direct)
Cole G BradleyCOO2017-01-10Sell5,00035,882$29.22146.16.0235,882 (Direct)
Cole G BradleyCOO2016-12-06Sell5,00035,882$30.61153.051.2135,882 (Direct)
Popovits Kimberly JPresident and CEO2016-12-05Sell5,000289,594$30.02150.13.259,620 (Direct)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
200,851 (Held by the Popovits 2010 Trust)
Leber LauraChief Communication Officer2016-11-21Sell7,06814,331$31.73224.27-2.3614,331 (Direct)
Shak StevenChief Scientific Officer2016-11-10Sell5,000327,207$31.71158.55-2.3327,207 (Direct)
Cole G BradleyCOO2016-11-08Sell5,00035,426$29.68148.44.3835,426 (Direct)
Popovits Kimberly JPresident and CEO2016-11-03Sell5,313289,594$28.88153.447.2759,620 (Direct)
200,851 (Held by the Popovits 2010 Trust)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
Shak StevenChief Scientific Officer2016-10-11Sell5,000327,207$30.39151.951.94327,207 (Direct)
Cole G BradleyCOO2016-10-10Sell8,29035,426$30.59253.591.2735,426 (Direct)
Vaughn James JChief Commercial Officer2016-10-06Sell3,00026,079$29.6889.044.3826,079 (Direct)
Shak StevenChief Scientific Officer2016-09-13Sell5,000327,207$26.83134.1515.47327,207 (Direct)
Cole G BradleyCOO2016-09-06Sell4,00035,426$27.41109.6413.0235,426 (Direct)
Shak StevenChief Scientific Officer2016-08-23Sell5,000327,207$27.24136.213.73327,207 (Direct)
BAKER FELIXDirector, 10% Owner2016-08-15Buy100,00011,841,478$27.02270214.66
318,623 (See footnote(,))
11,348,958 (See footnote(,,))
173,897 (See footnote(F1,))
Cole G BradleyCOO2016-08-11Sell5,00035,426$28.87144.357.3135,426 (Direct)
Vaughn James JChief Commercial Officer2016-08-08Sell3,00029,079$28.7486.227.7929,079 (Direct)
Shak StevenChief Scientific Officer2016-07-19Sell5,000327,207$27.42137.112.98327,207 (Direct)
Cole G BradleyCOO2016-07-06Sell5,00035,426$26.64133.216.2935,426 (Direct)
Shak StevenChief Scientific Officer2016-06-21Sell5,000327,207$25.77128.8520.22327,207 (Direct)
Cole G BradleyCOO2016-06-09Sell5,00035,426$26.62133.116.3835,426 (Direct)
Vaughn James JChief Commercial Officer2016-06-06Sell1,99732,079$2855.9210.6432,079 (Direct)
Cole G BradleyCOO2016-05-16Sell5,00034,970$27.613812.2534,970 (Direct)
Febbo Phillip G.Chief Medical Officer2016-05-10Sell6,32415,013$27.2172.0113.915,013 (Direct)
Vaughn James JChief Commercial Officer2016-05-09Sell2,00031,255$285610.6431,255 (Direct)
Shak StevenChief Scientific Officer2016-05-04Sell10,000326,383$25.43254.321.82326,383 (Direct)
Vaughn James JChief Commercial Officer2016-02-09Sell324,076$280.0810.6424,076 (Direct)
LIVINGSTON RANDALL SDirector2016-01-13Sell1,2506,149$32.1440.18-3.616,149 (Direct)
Cole G BradleyCOO2016-01-12Sell4,00027,428$31.69126.76-2.2427,428 (Direct)
Vaughn James JChief Commercial Officer2016-01-07Sell2,00024,076$33.6367.26-7.8824,076 (Direct)
Cole G BradleyCOO2015-12-08Sell4,00027,428$29.26117.045.8827,428 (Direct)
Leber LauraChief Communication Officer2015-12-07Sell4,20012,959$29.33123.195.6312,959 (Direct)
Vaughn James JChief Commercial Officer2015-12-07Sell2,00024,076$29.3358.665.6324,076 (Direct)
Cole G BradleyCOO2015-11-10Sell4,00030,326$26.03104.1219.0230,326 (Direct)
Cole G BradleyCOO2015-09-09Sell9,66430,326$25.35244.9822.2130,326 (Direct)
Cole G BradleyCOO2015-07-07Sell4,00030,326$27.53110.1212.5330,326 (Direct)
Cole G BradleyCOO2015-06-09Sell4,00030,326$26.24104.9618.0630,326 (Direct)
Cole G BradleyCOO2015-05-12Sell4,00029,658$27.54110.1612.4929,658 (Direct)
Popovits Kimberly JPresident and CEO2015-04-13Sell3,000203,001$31.2893.84-0.96Link
Cole G BradleyCOO2015-04-07Sell4,00029,658$30.44121.761.7729,658 (Direct)
Popovits Kimberly JPresident and CEO2015-03-12Sell3,000204,101$31.9195.73-2.91Link
Cole G BradleyCOO2015-03-10Sell4,00029,658$31.84127.36-2.729,658 (Direct)
Popovits Kimberly JPresident and CEO2015-02-12Sell3,000204,601$29.8689.583.75Link
Cole G BradleyCOO2015-02-10Sell4,00021,645$31.37125.48-1.2421,645 (Direct)
LIVINGSTON RANDALL SDirector2015-02-02Sell1,0006,149$31.9331.93-2.986,149 (Direct)
Popovits Kimberly JPresident and CEO2015-01-12Sell3,000204,601$33.46100.38-7.41Link
Popovits Kimberly JPresident and CEO2014-12-11Sell3,000204,601$32.9998.97-6.09Link
Cole G BradleyCOO2014-12-08Sell4,33621,645$32.52141.01-4.7421,645 (Direct)
Popovits Kimberly JPresident and CEO2014-11-12Sell4,300205,201$34.82149.73-11.03Link
Cole G BradleyCOO2014-11-10Sell4,00022,891$35.35141.4-12.3622,891 (Direct)
LIVINGSTON RANDALL SDirector2014-11-03Sell3,0006,149$36.24108.72-14.516,149 (Direct)
Popovits Kimberly JPresident and CEO2014-10-13Sell3,000205,201$30.7892.340.65Link
Cole G BradleyCOO2014-10-08Sell4,00022,891$28.77115.087.6822,891 (Direct)
Popovits Kimberly JPresident and CEO2014-09-11Sell3,000205,201$29.8289.463.89Link
Cole G BradleyCOO2014-09-08Sell4,70022,891$30.09141.422.9622,891 (Direct)
Shak StevenEVP of R&D2014-08-14Sell13,348312,298$27.36365.213.23312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-08-12Sell3,000205,201$26.0778.2118.83Link
Popovits Kimberly JPresident and CEO2014-07-14Sell3,000205,201$26.5979.7716.51Link
Cole G BradleyCOO2014-07-08Sell2,30022,891$27.0562.2214.5322,891 (Direct)
Shak StevenEVP of R&D2014-07-01Sell7,000312,298$2718914.74312,298 (Direct)
Shak StevenEVP of R&D2014-06-12Sell7,000312,298$26.73187.1115.9312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-06-12Sell3,000271,289$26.178.318.7Link
Schorno Dean LCFO2014-06-10Sell4,00030,673$27.62110.4812.1724,524 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2014-06-09Sell2,33722,891$27.2963.7813.5222,891 (Direct)
Popovits Kimberly JPresident and CEO2014-05-12Sell3,000270,579$26.5479.6216.73Link
Schorno Dean LCFO2014-05-09Sell4,00029,963$25.09100.3623.4823,814 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Shak StevenEVP of R&D2014-04-14Sell7,000311,588$26.25183.7518.02311,588 (Direct)
Cole G BradleyCOO2014-04-08Sell3,00022,226$278114.7422,226 (Direct)
Shak StevenEVP of R&D2014-03-14Sell7,000311,588$28.36198.529.24311,588 (Direct)
Cole G BradleyCOO2014-03-10Sell3,00022,226$27.7683.2811.622,226 (Direct)
HIBBS KATHY LSVP & General Counsel2014-02-18Sell1,31215,787$27.8836.5811.1215,787 (Direct)
Shak StevenEVP of R&D2014-02-14Sell7,000311,588$27.38191.6613.15311,588 (Direct)
Cole G BradleyCOO2014-02-10Sell3,00024,789$278114.7424,789 (Direct)
Shak StevenEVP of R&D2014-01-15Sell7,000308,283$31.51220.57-1.68308,283 (Direct)
Popovits Kimberly JPresident and CEO2014-01-13Sell2,500261,190$30753.27Link
Cole G BradleyCOO2014-01-08Sell3,00018,369$28.1784.519.9818,369 (Direct)
Shak StevenEVP of R&D & CMO2013-12-17Sell14,000308,283$29.57413.984.77308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-12-12Sell2,5000$30.6876.70.98Link
Schorno Dean LCFO2013-12-09Sell3,00027,706$33.2599.75-6.8321,557 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-12-02Sell1,0006,149$34.9234.92-11.286,149 (Direct)
Popovits Kimberly JPresident and CEO2013-11-13Sell5,0000$34.58172.9-10.41Link
Schorno Dean LCFO2013-11-08Sell3,00027,585$33.36100.08-7.1321,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-11-06Sell2,86818,135$31.3890-1.2718,135 (Direct)
Shak StevenEVP of R&D & CMO2013-10-15Sell5,000308,283$29.67148.354.42308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-10-10Sell2,5000$30753.27Link
Cole G BradleyCOO2013-10-09Sell2,50018,135$29.9574.883.4418,135 (Direct)
Shak StevenEVP of R&D & CMO2013-09-18Sell5,000313,283$33.73168.65-8.15313,283 (Direct)
Popovits Kimberly JPresident and CEO2013-09-12Sell2,5000$34.3185.78-9.71Link
Cole G BradleyCOO2013-09-09Sell2,50018,135$32.5381.33-4.7618,135 (Direct)
Schorno Dean LCFO2013-09-06Sell4,00027,585$32.9131.6-5.8421,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-09-03Sell1,0006,149$31.4931.49-1.626,149 (Direct)
Shak StevenEVP of R&D & CMO2013-08-14Sell5,000318,283$32.98164.9-6.06318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-08-12Sell2,5000$33.0382.58-6.21Link
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-6.5521,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-6.5521,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-08-07Sell2,50019,135$33.6684.15-7.9619,135 (Direct)
Shak StevenEVP of R&D & CMO2013-07-23Sell5,000318,283$35.33176.65-12.31318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-07-12Sell5,0000$34.61173.05-10.49Link
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.24-8.3717,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.24-8.3717,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-07-08Sell2,50013,135$33.3383.33-7.0513,135 (Direct)
Shak StevenEVP of R&D & CMO2013-06-18Sell5,000323,283$33.52167.6-7.58323,283 (Direct)
Popovits Kimberly JPresident and CEO2013-06-12Sell5,0000$35.68178.4-13.17Link
Schorno Dean LCFO2013-06-10Sell4,00023,985$35.88143.52-13.6617,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-06-05Sell2,50013,135$36.4791.18-15.0513,135 (Direct)
BAKER FELIXDirector, 10% Owner2013-06-05Buy381,43213,288,253$36.1613792.58-14.33
1,730,777 (See Footnote)
11,241,654 (See Footnotes(F7,F14,F15))
301,215 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-06-03Buy179,58312,906,821$36.716592.49-15.61
1,690,226 (See Footnote)
10,909,066 (See Footnotes(F7,F14,F15))
292,922 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-06-03Sell1,0006,149$36.436.4-14.896,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-29Buy121,26612,727,238$36.894473.5-16.02
1,671,081 (See Footnote)
10,752,532 (See Footnotes(F7,F14,F15))
289,018 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-05-24Buy79,41714,257,273$36.932932.87-16.11
1,651,301 (See Footnote)
10,646,920 (See Footnotes(F7,F17,F18))
286,384 (See Footnotes(F9,F17,F18))
1,658,061 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-22Sell1,0007,087$37.4837.48-17.347,087 (Direct)
Shak StevenEVP of R&D & CMO2013-05-21Sell5,000327,380$37.19185.95-16.7327,380 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-16Buy71,43912,526,555$36.452603.95-15.01
1,649,473 (See Footnote)
10,577,816 (See Footnotes(F7,F14,F15))
284,659 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-05-15Sell1,3376,149$35.8347.9-13.546,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-14Buy240,42614,093,759$34.348256.23-9.78
1,638,643 (See Footnote)
10,515,769 (See Footnotes(F7,F17,F18))
283,112 (See Footnotes(F9,F17,F18))
1,641,628 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-13Sell1,2507,087$34.4243.03-9.997,087 (Direct)
Popovits Kimberly JPresident and CEO2013-05-13Sell5,0000$34.7173.5-10.72Link
Schorno Dean LCFO2013-05-09Sell4,00023,241$36.02144.08-13.9917,092 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-05-08Sell2,50012,540$35.9989.98-13.9212,540 (Direct)
Popovits Kimberly JPresident and CEO2013-04-23Sell2,5000$30753.27Link
Cole G BradleyCOO2013-04-03Sell2,50012,540$27.7969.4811.4812,540 (Direct)
Cole G BradleyCOO2013-03-06Sell2,50012,540$28.5771.438.4412,540 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-21Buy49,08512,211,834$27.781363.5811.52
1,614,513 (See Footnote)
10,306,239 (See Footnotes(F7,F14,F15))
277,189 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
HIBBS KATHY LSVP & General Counsel2013-02-20Sell2,7167,087$28.1376.410.137,087 (Direct)
MYERS WOODROW A JRDirector2013-02-14Sell41,2502,891$28.41171.59.082,891 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-14Buy52,00012,162,749$28.481480.968.78
1,609,152 (See Footnote)
10,263,580 (See Footnotes(F7,F14,F15))
276,124 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-02-11Buy116,36012,110,749$28.153275.5310.05
1,603,265 (See Footnote)
10,218,600 (See Footnotes(F7,F14,F15))
274,991 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-02-06Sell2,50014,085$28.0370.0810.5214,085 (Direct)
LIVINGSTON RANDALL SDirector2013-01-28Sell2,0006,149$28.7757.547.686,149 (Direct)
Schorno Dean LCFO2013-01-09Sell2,62523,504$2873.510.6417,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-01-09Sell2,50014,085$27.8869.711.1214,085 (Direct)
Shak StevenEVP of R&D & CMO2012-12-18Sell5,000333,768$27.74138.711.68333,768 (Direct)
Popovits Kimberly JPresident and CEO2012-12-13Sell5,0000$27.79138.9511.48Link
Schorno Dean LCFO2012-12-11Sell3,00023,504$288410.6417,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2012-11-26Sell2,0006,149$27.8455.6811.286,149 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-21Buy229,30012,263,857$26.836152.1215.47288 (Direct)
271,800 (See Footnote)
1,589,551 (See Footnotes(F5,F14,F15))
10,117,174 (See Footnotes(F7,F14,F15))
271,806 (See Footnotes(F9,F14,F15))
13,238 (See Footnote(F9,F14,F15))
Shak StevenEVP of R&D & CMO2012-11-20Sell5,000338,768$26.94134.715338,768 (Direct)
COLELLA SAMUEL DDirector2012-11-20Sell30,61636,437$26.89823.2615.2136,437 (Direct)
0 (Versant Venture Capital I, L.P.)
0 (Versant Side Fund I, L.P.)
0 (Versant Affiliates Fund I-A, L.P.)
0 (Versant Affiliates Fund I-B, L.P.)
BAKER FELIXDirector, 10% Owner2012-11-14Buy103,16713,526$27.322818.5213.4288 (Direct)
13,238 (See Footnote)
Popovits Kimberly JPresident and CEO2012-11-14Sell5,0000$27.24136.213.73Link
BAKER FELIXDirector, 10% Owner2012-11-13Buy823,77213,526$27.8122909.111.4288 (Direct)
13,238 (See Footnote)
Schorno Dean LCFO2012-11-12Sell3,00023,504$288410.6417,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-11-08Sell2,50014,085$28.6271.558.2514,085 (Direct)
Popovits Kimberly JPresident and CEO2012-10-16Sell10,0000$33.08330.8-6.35Link
Shak StevenEVP of R&D & CMO2012-10-16Sell5,000343,768$35.25176.25-12.11343,768 (Direct)
Schorno Dean LCFO2012-10-12Sell3,00023,504$33.79101.37-8.3217,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
HIBBS KATHY LSVP & General Counsel2012-10-11Sell1,25011,367$33.7842.23-8.2911,367 (Direct)
Cole G BradleyCOO2012-10-09Sell2,50014,085$34.887-10.9814,085 (Direct)
Shak StevenEVP of R&D & CMO2012-09-18Sell5,000348,768$33.76168.8-8.23348,768 (Direct)
Popovits Kimberly JPresident and CEO2012-09-13Sell5,0000$31.69158.45-2.24Link
Cole G BradleyCOO2012-09-06Sell2,50014,085$35.0187.53-11.5114,085 (Direct)
MYERS WOODROW A JRDirector2012-08-21Sell16,5002,236$35.2580.8-11.992,236 (Direct)
Shak StevenEVP of R&D & CMO2012-08-20Sell5,000353,768$34.99174.95-11.46353,768 (Direct)
Popovits Kimberly JPresident and CEO2012-08-13Sell10,0000$34.72347.2-10.77Link
Cole G BradleyCOO2012-08-08Sell2,50014,085$30.4976.231.6114,085 (Direct)
LIVINGSTON RANDALL SDirector2012-07-26Sell2,0006,149$35.971.8-13.76,149 (Direct)
Shak StevenChief Medical Officer2012-07-24Sell5,000358,768$34.24171.2-9.52358,768 (Direct)
Popovits Kimberly JPresident and CEO2012-07-13Sell7,1000$34.76246.8-10.87Link
Scott Randal WCEO, InVitae Corporation*2012-07-11Sell30,0000$35.391061.7-12.46Link
Cole G BradleyCOO2012-07-05Sell2,50014,085$35.9589.88-13.8214,085 (Direct)
Shak StevenChief Medical Officer2012-06-25Sell5,000363,768$33.25166.25-6.83363,768 (Direct)
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-7.13Link
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-7.13Link
Scott Randal WCEO, InVitae Corporation*2012-06-12Sell30,0000$33.541006.2-7.63Link
Cole G BradleyCOO2012-06-06Sell2,50013,507$33.9784.93-8.813,507 (Direct)
Shak StevenChief Medical Officer2012-05-24Sell5,000367,849$33.8169-8.34367,849 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-22Buy167,4061,488,539$32.265400.52-3.97
1,488,539 (See Footnote)
COLELLA SAMUEL DDirector2012-05-18Sell26,294664,113$33.03868.49-6.2126,891 (Direct)
582,174 (Versant Venture Capital I, L.P.)
11,210 (Versant Side Fund I, L.P.)
13,222 (Colella Family Partners, L.P.)
10,414 (Versant Affiliates Fund I-A, L.P.)
20,202 (Versant Affiliates Fund I-B, L.P.)
BAKER JULIANDirector, 10% Owner2012-05-16Buy376,0591,488,539$33.8812740.88-8.56
1,488,539 (See Footnote)
Popovits Kimberly JPresident and CEO2012-05-16Sell10,0000$34.23342.3-9.49Link
Schorno Dean LCFO2012-05-15Sell1,00023,504$33.6933.69-8.0417,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER JULIANDirector, 10% Owner2012-05-11Buy114,8881,488,539$29.963442.043.4
1,488,539 (See Footnote)
Scott Randal WCEO, InVitae Corporation*2012-05-11Sell30,0000$30.22906.62.51Link
Cole G BradleyCOO2012-05-09Sell2,50013,507$28.8772.187.3113,507 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-08Buy195,70113,238$28.455567.698.89
13,238 (See Footnote)
LIVINGSTON RANDALL SDirector2012-04-26Sell2,0006,149$28.2156.429.826,149 (Direct)
Shak StevenChief Medical Officer2012-04-24Sell5,000372,849$27.93139.6510.92372,849 (Direct)
Popovits Kimberly JPresident and CEO2012-04-23Sell5,0000$27.79138.9511.48Link
Schorno Dean LCFO2012-04-16Sell1,00024,504$27.9827.9810.7218,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation*2012-04-11Sell20,0000$28.59571.88.36Link
Cole G BradleyCOO2012-04-04Sell2,50013,507$30.2875.72.3113,507 (Direct)
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.42.99377,849 (Direct)
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.353.03Link
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.353.03Link
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.42.99377,849 (Direct)
Schorno Dean LCFO2012-03-15Sell1,00025,504$31.0831.08-0.3219,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation2012-03-13Sell30,0000$31.05931.5-0.23Link
Cole G BradleyCOO2012-03-08Sell2,50013,507$29.9474.853.4713,507 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-08Buy4,5081,484,977$30.11135.742.89
1,484,977 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-08Buy1,099227,840$30.1133.092.89
227,840 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-08Buy41,5848,255,421$30.111252.092.89
8,255,421 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-05Buy261,7618,213,837$29.817803.13.92
8,213,837 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-05Buy6,923226,741$29.81206.373.92
226,741 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-05Buy31,3321,480,469$29.81934.013.92
1,480,469 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-29Buy6,476219,818$29.06188.196.61
219,818 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-29Buy245,0317,952,076$29.067120.66.61
7,952,076 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-29Buy29,7561,449,137$29.06864.716.61
1,449,137 (Through Partnership)
Popovits Kimberly JPresident and CEO2012-02-24Sell10,0000$28.52858.7Link
Shak StevenChief Medical Officer2012-02-23Sell5,000382,849$28.14140.710.09382,849 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-23Buy114,5187,707,045$28.063213.3810.41
7,707,045 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-23Buy3,022213,342$28.0684.810.41
213,342 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-23Buy13,3321,419,381$28.06374.110.41
1,419,381 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-16Buy33,1851,406,049$29.34973.655.59
1,406,049 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-16Buy7,213210,320$29.37211.855.48
210,320 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-16Buy272,9097,592,527$29.378015.345.48
7,592,527 (Through Partnership)
Schorno Dean LCFO2012-02-15Sell1,00026,504$28.7628.767.7220,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2012-02-15Sell75526,749$28.7621.717.7220,600 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.618.33Link
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-10Buy417,9157,319,618$26.3611016.2417.53
7,319,618 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-10Buy11,043203,107$26.36291.0917.53
203,107 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-10Buy66,5831,372,864$26.361755.1317.53
1,372,864 (Through Partnership)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.618.33Link
Cole G BradleyCOO2012-02-08Sell2,50014,450$26.4766.1817.0414,450 (Direct)
LIVINGSTON RANDALL SDirector2012-01-26Sell2,0006,149$27.5155.0212.616,149 (Direct)
Popovits Kimberly JPresident and CEO2012-01-25Sell5,0000$26.42132.117.26Link
Popovits Kimberly JPresident and CEO2012-01-24Sell5,0000$26.62133.116.38Link
Shak StevenChief Medical Officer2012-01-24Sell5,000382,778$26.74133.715.86382,778 (Direct)
Schorno Dean LCFO2012-01-17Sell1,00024,049$282810.6417,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-01-12Sell2,5007,750$27.5468.8512.497,750 (Direct)
Scott Randal WExecutive Chairman2012-01-11Sell20,0000$27.46549.212.82Link
Shak StevenChief Medical Officer2011-12-22Sell5,000387,778$26.03130.1519.02387,778 (Direct)
Scott Randal WExecutive Chairman2011-12-13Sell20,0000$27.29545.813.52Link
Cole G BradleyCOO2011-12-06Sell2,5007,750$28.5971.488.367,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-12-05Buy3,152192,064$28.1288.6310.17
192,064 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-12-05Buy45,9771,306,281$27.661271.7212
1,306,281 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-12-05Buy117,7516,901,703$28.123311.1610.17
6,901,703 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-23Buy5,5311,260,304$25.91143.3119.57
1,260,304 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-23Buy5,750188,912$25.94149.1619.43
188,912 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-23Buy193,7396,783,952$25.915019.7819.57
6,783,952 (Through Partnership)
Shak StevenChief Medical Officer2011-11-22Sell5,000392,778$26.07130.3518.83392,778 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-16Buy64,5976,590,213$27.711789.9811.8
6,590,213 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-16Buy2,550183,162$27.7170.6611.8
183,162 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-16Buy4581,254,773$27.3512.5313.27
1,254,773 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-14Buy10,106180,612$27.23275.1913.77
180,612 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-14Buy249,3756,525,616$27.236790.4813.77
6,525,616 (Through Partnership)
Scott Randal WExecutive Chairman2011-11-11Sell20,0000$27.24544.813.73Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-09Buy5421,254,315$26.7914.5215.64
1,254,315 (Through Partnership)
Cole G BradleyCOO2011-11-08Sell2,5007,750$26.666.516.477,750 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-07Buy209,5126,276,241$25.945434.7419.43
6,276,241 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-07Buy8,847170,506$25.94229.4919.43
170,506 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-03Buy1201,253,773$24.482.9426.55
1,253,773 (Through Partnership)
LIVINGSTON RANDALL SDirector2011-10-27Sell2,0006,149$22.0844.1640.316,149 (Direct)
Shak StevenChief Medical Officer2011-10-24Sell5,000392,778$21.76108.842.37392,778 (Direct)
Scott Randal WExecutive Chairman2011-10-11Sell20,0000$22.83456.635.7Link
Cole G BradleyCOO2011-10-06Sell5,0007,750$22.31111.5538.867,750 (Direct)
Scott Randal WExecutive Chairman2011-09-13Sell20,0000$20.81416.248.87Link
Cole G BradleyCOO2011-09-06Sell2,5007,750$22.0855.240.317,750 (Direct)
Shak StevenChief Medical Officer2011-08-24Sell5,000392,778$23.02115.134.58392,778 (Direct)
Scott Randal WExecutive Chairman2011-08-11Sell20,0000$24.44488.826.76Link
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.1522.647,750 (Direct)
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.1522.647,750 (Direct)
LIVINGSTON RANDALL SDirector2011-07-27Sell2,0006,149$26.4552.917.136,149 (Direct)
Shak StevenChief Medical Officer2011-07-25Sell5,000392,778$27.61138.0512.21392,778 (Direct)
Scott Randal WExecutive Chairman2011-07-12Sell20,0001,503,444$27.36547.213.231,491,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Cole G BradleyCOO2011-07-06Sell5,0007,750$27.74138.711.687,750 (Direct)
Shak StevenChief Medical Officer2011-06-23Sell5,000392,778$27.12135.614.23392,778 (Direct)
Schorno Dean LCFO2011-06-15Sell1,00025,049$25.9125.9119.5718,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-06-13Sell20,0001,523,444$25.69513.820.591,511,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-09Buy119194,415$26.193.1218.29
194,415 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-06-09Buy4,388161,659$26.19114.9218.29
161,659 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-09Buy203,6526,059,449$26.25335.6818.24
6,059,449 (Through Partnership)
Cole G BradleyCOO2011-06-06Sell2,5007,750$26.1865.4518.337,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-06-01Buy4,631157,271$27.34126.6113.31
157,271 (Through Partnership)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-01Buy112194,296$27.353.0613.27
194,296 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-01Buy181,6935,855,797$27.354969.313.27
5,855,797 (Through Partnership)
Shak StevenChief Medical Officer2011-05-25Sell5,000392,778$25.55127.7521.25392,778 (Direct)
Schorno Dean LCFO2011-05-12Sell1,00026,049$26.4826.4816.9919,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-05-11Sell20,0000$26.66533.216.2Link
Cole G BradleyCOO2011-05-09Sell2,5007,750$25.9364.8319.487,750 (Direct)
LIVINGSTON RANDALL SDirector2011-04-27Sell2,0000$26.0452.0818.97Link
Shak StevenChief Medical Officer2011-04-25Sell5,0000$25.38126.922.06Link
Popovits Kimberly JPresident and CEO2011-04-15Sell8,0000$25.49203.9221.54Link
Schorno Dean LCFO2011-04-14Sell1,0000$25.3225.3222.35Link
Scott Randal WExecutive Chairman2011-04-12Sell20,0000$25.96519.219.34Link
Cole G BradleyCOO2011-04-06Sell5,0000$26.91134.5515.12Link
Shak StevenChief Medical Officer2011-03-24Sell5,0000$24.45122.2526.71Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.3227.54Link
Schorno Dean LCFO2011-03-15Sell1,0000$23.7923.7930.22Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.3227.54Link
Scott Randal WExecutive Chairman2011-03-11Sell20,0000$25.62512.420.92Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-10Buy70,8560$26.031844.3819.02Link
Cole G BradleyCOO2011-03-08Sell2,5000$25.2363.0822.79Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-08Buy9,6480$25.06241.7823.62Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-08Buy349,5660$25.068760.1223.62Link
COLELLA SAMUEL DDirector2011-03-03Sell34,3200$25.45873.4421.73Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-02Buy160,3370$25.694119.0620.59Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-02Buy4,4260$25.69113.720.59Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-02-25Buy158,3550$23.393703.9232.45Link
14159 capital (GP), LLCDirector, 10% Owner2011-02-25Buy4,3700$23.39102.2132.45Link
Shak StevenChief Medical Officer2011-02-24Sell5,0000$23.27116.3533.13Link
Schorno Dean LCFO2011-02-15Sell1,0000$22.5122.5137.63Link
Popovits Kimberly JPresident and CEO2011-02-15Sell8,0000$22.51180.0837.63Link
Scott Randal WExecutive Chairman2011-02-11Sell20,0000$22.244439.55Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,0000$21.15169.246.48Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,000309,424$21.15169.246.48Link
Schorno Dean LCFO2011-01-13Sell1,27626,149$21.0626.8747.1Link
Scott Randal WExecutive Chairman2011-01-11Sell20,0001,642,410$21.73434.642.57Link
Cole G BradleyCOO2011-01-06Sell5,0001,000$22.13110.6539.99Link
Popovits Kimberly JPresident and CEO2010-12-16Sell8,000310,624$22.71181.6836.42Link
Scott Randal WExecutive Chairman2010-12-13Sell20,0001,696,410$22.46449.237.93Link
Cole G BradleyCOO & CFO2010-12-13Sell2,5001,000$22.6456.636.84Link
Popovits Kimberly JPresident and CEO2010-11-16Sell8,000310,624$17.514077.03Link
Cole G BradleyCOO & CFO2010-11-11Sell2,5001,000$18.0445.171.73Link
Scott Randal WExecutive Chairman2010-11-11Sell20,0001,666,410$18.27365.469.57Link
Scott Randal WExecutive Chairman2010-10-12Sell20,0001,686,410$13.95279122.08Link
Popovits Kimberly JPresident and CEO2010-09-15Sell7,734310,624$15.1116.78105.17Link
Scott Randal WExecutive Chairman2010-09-13Sell20,0001,706,410$14.87297.4108.34Link
Cole G BradleyCOO & CFO2010-09-13Sell2,5001,000$15.0137.53106.4Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-09Buy145134,196$14.812.15109.18Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-09Buy5,2614,934,990$14.8177.92109.18Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-02Buy65,4664,929,729$14.46946.64114.25Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-02Buy1,807134,051$14.4626.13114.25Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-30Buy3,415132,244$14.3749.07115.59Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-30Buy123,7114,864,263$14.371777.73115.59Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-23Buy150,4694,740,552$14.522184.81113.36Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-23Buy4,153128,829$14.5260.3113.36Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-18Buy530124,676$14.997.94106.67Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-18Buy19,1874,590,083$14.99287.61106.67Link
Popovits Kimberly JPresident and CEO2010-08-17Sell8,000288,116$15.07120.56105.57Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-13Buy2,924124,146$14.8543.42108.62Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-13Buy105,9104,570,896$14.851572.76108.62Link
Cole G BradleyCOO & CFO2010-08-12Sell2,5001,000$1537.5106.53Link
Scott Randal WExecutive Chairman2010-08-11Sell20,0001,726,410$14.71294.2110.61Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-10Buy164,2424,464,986$14.612399.58112.05Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-10Buy4,533121,222$14.6166.23112.05Link
Baker JoffreChief Scientific Officer2010-08-09Sell4,629163,088$14.7568.28110.03Link
Scott Randal WExecutive Chairman2010-07-13Sell20,0001,746,410$12.81256.2141.84Link
Baker JoffreChief Scientific Officer2010-07-07Sell4,629167,717$13.0560.41137.39Link
Scott Randal WExecutive Chairman2010-06-11Sell20,0001,766,410$14.15283118.94Link
Baker JoffreChief Scientific Officer2010-06-10Sell4,629172,346$14.0565.04120.5Link
Popovits Kimberly JPresident and CEO2010-05-17Sell8,000310,624$15.78126.2496.32Link
Cole G BradleyCOO & CFO2010-05-12Sell2,5001,000$15.8739.6895.21Link
Scott Randal WExecutive Chairman2010-05-11Sell20,0001,776,410$15.61312.298.46Link
Baker JoffreChief Scientific Officer2010-05-10Sell4,629176,975$15.5171.899.74Link
Scott Randal WExecutive Chairman2010-04-13Sell20,0001,796,410$16.87337.483.64Link
Cole G BradleyCOO & CFO2010-04-12Sell5,0001,000$16.984.583.31Link
Baker JoffreChief Scientific Officer2010-04-12Sell4,629181,604$16.8878.1483.53Link
Popovits Kimberly JPresident and CEO2010-03-16Sell20,000288,116$19.4538959.28Link
Scott Randal WExecutive Chairman2010-03-11Sell20,0001,800,646$19.338660.52Link
Cole G BradleyCOO & CFO2010-03-11Sell2,5001,000$19.3948.4859.77Link
COLELLA SAMUEL DDirector2010-03-10Sell106,70085,050$19.452075.3259.28Link
Baker JoffreChief Scientific Officer2010-03-08Sell4,629150,120$19.8391.7956.23Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-19Buy3,645116,689$17.0562.1581.7Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-19Buy132,0704,300,744$17.052251.7981.7Link
Scott Randal WExecutive Chairman2010-02-11Sell20,0001,830,646$17.23344.679.8Link
Cole G BradleyCOO & CFO2010-02-11Sell2,5001,000$17.5143.7876.93Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-10Buy9,437113,044$17.01160.5282.13Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-10Buy341,8544,168,674$17.015814.9482.13Link
Baker JoffreChief Scientific Officer2010-02-09Sell4,629145,491$17.1479.3480.75Link
Cole G BradleyCOO & CFO2010-01-12Sell5,0001,000$17.2586.2579.59Link
Baker JoffreChief Scientific Officer2010-01-11Sell4,629150,120$17.4780.8777.33Link
Shak StevenChief Medical Officer2009-12-21Sell5,000388,278$20.12100.653.98Link
Popovits Kimberly JPresident and CEO2009-12-15Sell5,000313,506$20.39101.9551.94Link
Cole G BradleyCOO & CFO2009-12-14Sell2,0001,000$20.4240.8451.71Link
Scott Randal WExecutive Chairman2009-12-11Sell12,0001,880,646$20.24242.8853.06Link
Baker JoffreChief Scientific Officer2009-12-08Sell4,629154,749$20.2693.7852.91Link
Popovits Kimberly JPresident and CEO2009-11-17Sell20,000318,506$19.21384.261.27Link
Cole G BradleyCOO & CFO2009-11-12Sell6653,000$20.0413.3354.59Link
Scott Randal WExecutive Chairman2009-11-11Sell12,0001,892,646$19.99239.8854.98Link
Baker JoffreChief Scientific Officer2009-11-10Sell4,629159,378$2092.5854.9Link
Shak StevenChief Medical Officer2009-10-20Sell5,000393,278$20.65103.2550.02Link
Popovits Kimberly JPresident and CEO2009-10-15Sell5,000338,506$20.42102.151.71Link
Scott Randal WExecutive Chairman2009-10-13Sell12,0001,904,646$20.66247.9249.95Link
Baker JoffreChief Scientific Officer2009-10-07Sell4,629164,007$21.179846.34Link
Shak StevenChief Medical Officer2009-09-22Sell5,000398,278$21.13105.6546.62Link
Popovits Kimberly JPresident and CEO2009-09-15Sell5,000343,506$20.73103.6549.45Link
Scott Randal WExecutive Chairman2009-09-11Sell12,0001,916,646$20.67248.0449.88Link
Baker JoffreChief Scientific Officer2009-09-04Sell4,629168,636$20.1293.1453.98Link
Shak StevenChief Medical Officer2009-08-25Sell5,000403,278$20.77103.8549.16Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-17Buy1,839103,607$19.9836.7455.06Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-17Buy66,6303,826,820$19.981331.2755.06Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-17Buy34194,184$19.980.6855.06Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-17Buy11,6571,253,653$19.98232.9155.06Link
Popovits Kimberly JPresident and CEO2009-08-17Sell5,000348,506$19.5397.6558.63Link
Cole G BradleyCOO & CFO2009-08-13Sell5,0003,000$2010054.9Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-12Buy15,8771,241,996$19.49309.4458.95Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-12Buy45194,150$19.50.8858.87Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-12Buy90,7543,760,190$19.491768.858.95Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-12Buy2,508101,768$19.4948.8858.95Link
Scott Randal WExecutive Chairman2009-08-11Sell12,0001,928,646$19.42233.0459.53Link
Baker JoffreChief Scientific Officer2009-08-10Sell4,629173,265$19.4890.1759.03Link
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.1193.5
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.1193.5
Scott Randal WExecutive Chairman2009-06-11Sell6,0001,940,646$18.27109.6269.57
Baker JoffreChief Scientific Officer2009-06-08Sell4,629182,523$17.6981.8975.13
Shak StevenChief Medical Officer2009-05-26Sell5,000408,278$199563.05
14159 capital (GP), LLCDirector, 10% Owner2009-05-21Buy1,10899,260$17.9719.9172.4
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-21Buy90194,161$17.971.6272.4
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-21Buy39,7783,669,436$17.97714.8172.4
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-21Buy25194,105$17.970.4572.4
Popovits Kimberly JPresident and CEO2009-05-15Sell5,000353,506$20.12100.653.98
Scott Randal WExecutive Chairman2009-05-12Sell12,0001,946,646$19.46233.5259.2
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-11Buy88194,080$19.551.7258.47
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-11Buy312194,071$19.556.158.47
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-11Buy137,4663,629,658$19.552687.4658.47
14159 capital (GP), LLCDirector, 10% Owner2009-05-11Buy3,82798,152$19.5574.8258.47
Baker JoffreChief Scientific Officer2009-05-08Sell4,629187,152$19.7291.2857.1
Scott Randal WExecutive Chairman2009-04-14Sell12,0001,958,646$25.47305.6421.63
Baker JoffreChief Scientific Officer2009-04-01Sell4,629191,781$25.27116.9722.6
Scott Randal WExecutive Chairman2009-03-11Sell12,0001,970,646$19.4232.859.69
Baker JoffreChief Scientific Officer2009-03-03Sell4,629196,410$19.1388.5561.94
Cole G BradleyCOO & CFO2009-02-17Sell5,0003,000$21.52107.643.96
Baker JoffreChief Scientific Officer2009-02-12Sell4,629201,039$20.695.3650.39
Baker JoffreChief Scientific Officer2009-02-12Sell4,62922,226$20.695.3650.39
Scott Randal WExecutive Chairman, Director2009-02-11Sell12,0001,982,646$20.85250.248.59
Baker JoffreChief Scientific Officer2009-01-12Sell4,62926,855$19.4189.8559.61
Shak StevenChief Medical Officer2008-12-22Sell100413,278$20.172.0253.59
Baker JoffreChief Scientific Officer2008-12-10Sell4,629205,668$19.2589.1160.94
Baker JoffreChief Scientific Officer2008-12-10Sell4,62931,484$19.2589.1160.94
Scott Randal WCEO, Director2008-12-09Sell12,0001,955,298$18.4220.868.37
Baker JoffreChief Scientific Officer2008-11-12Sell4,629210,297$19.8791.9855.91
Baker JoffreChief Scientific Officer2008-11-12Sell4,62936,113$19.8791.9855.91
Scott Randal WCEO, Director2008-11-11Sell12,0001,967,298$20.05240.654.51
Cole G BradleyEVP & CFO2008-11-10Sell10,0004,000$20.17201.753.59
Scott Randal WCEO, Director2008-10-14Sell12,0001,979,298$20.36244.3252.16
Baker JoffreChief Scientific Officer2008-10-01Sell9,25840,742$22.51208.437.63
Shak StevenChief Medical Officer2008-09-24Sell5,000413,378$22.67113.3536.66
Scott Randal WCEO, Director2008-09-16Sell12,0001,991,298$21.79261.4842.18
Shak StevenChief Medical Officer2008-08-26Sell5,000418,378$22.93114.6535.11
Baker JoffreChief Scientific Officer2008-08-26Sell4,629214,926$22.69105.0336.54
Cole G BradleyEVP & CFO2008-08-18Sell9,2984,000$23.67220.0830.88
Popovits Kimberly JPresident and COO2008-08-15Sell25,000358,506$24.2460627.81
Scott Randal WCEO, Director2008-08-12Sell12,0002,003,298$23.76285.1230.39
Scott Randal WCEO, Director2008-07-15Sell12,0002,015,298$2125247.52
Baker JoffreChief Scientific Officer2008-07-01Sell4,629219,555$19.2689.1560.85
Shak StevenChief Medical Officer2008-06-24Sell100423,378$20254.9
Scott Randal WCEO, Director2008-06-10Sell12,0002,027,298$19.92239.0455.52
Baker Brothers Life Sciences CDirector, 10% Owner2008-06-09Buy320,9833,492,192$19.916390.7755.6
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-06-09Buy76,0151,226,119$19.911513.4655.6
14159 capital (GP), LLCDirector, 10% Owner2008-06-09Buy10,29994,325$19.91205.0555.6
Baker JoffreChief Scientific Officer2008-06-02Sell4,629228,813$17.9983.2872.21
Scott Randal WCEO, Director2008-05-13Sell12,0002,039,298$18.7522565.23
Baker JoffreChief Scientific Officer2008-05-08Sell4,629233,442$19.2789.260.77
Scott Randal WCEO, Director2008-04-15Sell12,0002,051,298$17.22206.6479.91
Scott Randal WCEO, Director2008-03-11Sell12,0002,063,298$18.84226.0864.44
Baker JoffreChief Scientific Officer2008-03-05Sell4,629242,700$20.4894.851.27
Shak StevenChief Medical Officer2008-02-26Sell5,000423,478$20.23101.1553.14
Cole G BradleyEVP & CFO2008-02-19Sell9,0008,298$22.58203.2237.2
Scott Randal WCEO, Director2008-02-12Sell12,0002,075,298$23.01276.1234.64
Baker JoffreChief Scientific Officer2008-02-11Sell4,629247,329$22.94106.1935.05
Scott Randal WCEO, Director2008-01-15Sell12,0002,087,298$25.54306.4821.3
Baker JoffreChief Scientific Officer2008-01-02Sell4,629251,958$22.66104.8936.72
Baker JoffreChief Scientific Officer2007-12-03Sell4,6290$23.1106.9334.11
Popovits Kimberly JPresident and COO2007-11-27Sell6,655383,506$22146.4140.82
Scott Randal WCEO, Director2007-11-09Sell12,0002,111,299$23.07276.8434.29
Baker JoffreChief Scientific Officer2007-11-08Sell4,629265,845$23.21107.4433.48
Scott Randal WCEO2007-10-09Sell12,0002,123,299$20.16241.9253.67
Baker JoffreChief Scientific Officer2007-10-01Sell4,629270,474$19.8491.8456.15
Scott Randal WCEO, Director2007-09-11Sell12,0002,135,299$19.7236.457.26
Scott Randal WCEO2007-09-11Sell12,0002,135,299$19.69236.2857.34
Baker JoffreChief Scientific Officer2007-09-10Sell4,629275,103$19.5790.5958.3
Goldberg Michael DDirector2007-08-23Buy5,3505,350$18.76100.3765.14
Scott Randal WCEO2007-08-15Sell12,0002,147,299$19.91238.9255.6
Baker JoffreChief Scientific Officer2007-08-08Sell4,629279,732$19.4489.9959.36
Scott Randal WCEO2007-07-18Sell12,0002,159,299$21.18254.1646.27
Baker JoffreChief Scientific Officer2007-07-02Sell4,629284,361$19.018862.97
Scott Randal WCEO2007-06-19Sell12,0002,171,299$19.16229.9261.69
Baker JoffreChief Scientific Officer2007-06-01Sell4,629288,990$17.5681.2976.42
Baker Bros. Capital (GP), LLCDirector2007-05-30Buy545193,992$16.328.8989.83
Baker Biotech Capital (GP), LLDirector2007-05-30Buy81,1811,150,104$16.321324.8789.83
Baker Brothers Life Sciences CDirector2007-05-30Buy214,0993,171,209$16.323494.189.83
14159 capital (GP), LLCDirector2007-05-30Buy6,80784,026$16.32111.0989.83
14159 capital (GP), LLCDirector2007-05-24Buy16,26177,219$16.59269.7786.74
Baker Brothers Life Sciences CDirector2007-05-24Buy511,5532,957,110$16.598486.6686.74
Baker Biotech Capital (GP), LLDirector2007-05-24Buy193,9661,068,923$16.593217.986.74
Baker Bros. Capital (GP), LLCDirector2007-05-24Buy1,303193,447$16.5921.6286.74
14159 capital (GP), LLCDirector2007-05-21Buy22,49160,958$15.5348.6199.87
14159 capital (GP), LLCDirector2007-05-21Buy160,958$15.50.0299.87
Baker Brothers Life Sciences CDirector2007-05-21Buy707,4582,445,557$15.510965.699.87
Baker Biotech Capital (GP), LLDirector2007-05-21Buy268,248874,957$15.54157.8499.87
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.9599.87
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.9599.87
Scott Randal WCEO2007-05-08Sell12,0002,183,299$16.62199.4486.4
Baker JoffreChief Scientific Officer2007-05-08Sell4,629293,619$16.3175.589.94
Scott Randal WCEO2007-04-10Sell12,0002,195,299$17.27207.2479.39
Baker JoffreChief Scientific Officer2007-04-02Sell4,629298,248$17.1679.4380.54
Baker / Tisch Capital (GP), LLDirector2007-03-09Buy3,181193,759$18.2858.1569.47
Baker Bros. Capital (GP), LLCDirector2007-03-09Buy376190,341$18.286.8769.47
Baker Biotech Capital (GP), LLDirector2007-03-09Buy62,325606,709$18.281139.369.47
Baker Brothers Life Sciences CDirector2007-03-09Buy168,5601,738,099$18.283081.2869.47
14159 capital (GP), LLCDirector2007-03-09Buy5,37538,467$18.2898.2669.47
Scott Randal WCEO2007-03-06Sell12,0002,207,299$18.35220.268.83
Baker Bros. Capital (GP), LLCDirector2007-03-02Buy119189,965$18.092.1571.25
14159 capital (GP), LLCDirector2007-03-02Buy1,70733,092$18.0930.8871.25
Baker / Tisch Capital (GP), LLDirector2007-03-02Buy1,072190,578$18.119.471.16
Baker Biotech Capital (GP), LLDirector2007-03-02Buy19,795544,384$18.09358.0971.25
Baker Brothers Life Sciences CDirector2007-03-02Buy53,5331,569,539$18.09968.4171.25
Baker JoffreChief Scientific Officer2007-03-01Sell4,629302,877$18.1884.1670.41
MYERS WOODROW A JRDirector2007-02-21Buy2,00012,000$19.6339.2657.82
Baker Brothers Life Sciences CDirector2007-02-16Buy25,4121,516,006$18.54471.1467.1
Baker Biotech Capital (GP), LLDirector2007-02-16Buy9,396524,589$18.54174.267.1
Baker / Tisch Capital (GP), LLDirector2007-02-16Buy525189,506$18.549.7367.1
14159 capital (GP), LLCDirector2007-02-16Buy81131,385$18.5415.0467.1
Baker Bros. Capital (GP), LLCDirector2007-02-16Buy56189,846$18.541.0467.1
Baker Bros. Capital (GP), LLCDirector2007-02-14Buy579189,790$18.2510.5769.75
Baker / Tisch Capital (GP), LLDirector2007-02-14Buy5,346188,981$18.2597.5669.75
Baker Biotech Capital (GP), LLDirector2007-02-14Buy95,783515,193$18.251748.0469.75
14159 capital (GP), LLCDirector2007-02-14Buy8,25630,574$18.25150.6769.75
Baker Brothers Life Sciences CDirector2007-02-14Buy259,0441,490,594$18.254727.5569.75
Scott Randal WCEO2007-02-13Sell12,0002,219,299$18.12217.4470.97
Baker JoffreChief Scientific Officer2007-02-08Sell4,629307,506$18.9787.8163.31
Baker / Tisch Capital (GP), LLDirector2006-12-06Buy642183,635$21.5813.8543.56
Baker Brothers Life Sciences CDirector2006-12-06Buy34,1731,231,550$21.58737.4543.56
14159 capital (GP), LLCDirector2006-12-06Buy1,12022,318$21.5824.1743.56
Baker Biotech Capital (GP), LLDirector2006-12-06Buy12,237419,410$21.58264.0743.56
MYERS WOODROW A JRDirector2006-12-05Buy10,00010,000$21.97219.741.01
Baker / Tisch Capital (GP), LLDirector2006-12-05Buy9,096182,993$20.6187.3850.39
Baker Biotech Capital (GP), LLDirector2006-12-05Buy173,441407,173$20.63572.8850.39
14159 capital (GP), LLCDirector2006-12-05Buy15,88021,198$20.6327.1350.39
Baker Brothers Life Sciences CDirector2006-12-05Buy484,3331,197,377$20.69977.2650.39
14159 capital (GP), LLCDirector2006-09-08Buy5,3185,318$14.0574.72120.5Link
Baker Biotech Capital (GP), LLDirector2006-09-08Buy75,246233,732$14.051057.21120.5Link
Baker Brothers Life Sciences CDirector2006-09-08Buy237,236713,044$14.053333.17120.5Link
Baker Biotech Capital III (GP)10% Owner2005-10-04Buy136,316252,529$121635.79158.17Link
Baker Biotech Capital II (GP),10% Owner2005-10-04Buy38,684181,478$12464.21158.17Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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