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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Cole G BradleyCOO2017-06-13Sell5,00039,935$31.67158.354.9339,935 (Direct)
Popovits Kimberly JPresident and CEO
(Click for the stocks that their CEOs have bought)
2017-06-05Sell5,000307,567$32.32161.62.8279,057 (Direct)
199,387 (Held by the Popovits 2010 Trust)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
12,298 (Held by Morgan Stanley as Custodian for Benefit of Kimberly Popovits)
Shak StevenChief Scientific Officer2017-05-23Sell5,000331,103$29.414713.03331,103 (Direct)
Cohen Fred EDirector2017-05-19Sell8,25071,963$29.54243.7112.4965,895 (Direct)
6,068 (By the Jane K Cohen Trust)
Cohen Fred EDirector2017-05-18Sell16,50071,963$29.88493.0211.2165,895 (Direct)
6,068 (By the Jane K Cohen Trust)
Cohen Fred EDirector2017-05-16Sell8,25071,963$30.68253.118.3165,895 (Direct)
6,068 (By the Jane K Cohen Trust)
Popovits Kimberly JPresident and CEO2017-05-03Sell5,000306,846$31.77158.854.678,236 (Direct)
12,298 (Held by Morgan Stanley as Custodian for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
199,487 (Held by the Popovits 2010 Trust)
Shak StevenChief Scientific Officer2017-04-24Sell5,000331,103$31.46157.35.63331,103 (Direct)
Popovits Kimberly JPresident and CEO2017-04-03Sell5,000306,846$31.3156.56.1778,236 (Direct)
199,487 (Held by the Popovits 2010 Trust)
12,298 (Held by Morgan Stanley as Custodian for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
Shak StevenChief Scientific Officer2017-03-23Sell5,000331,103$31.26156.36.3331,103 (Direct)
Leber LauraChief Communication Officer2017-03-20Sell3,07214,627$31.8897.944.2314,627 (Direct)
Cole G BradleyCOO2017-03-08Sell5,71039,528$31.55180.155.3239,528 (Direct)
Popovits Kimberly JPresident and CEO2017-03-06Sell5,000308,210$31.09155.456.8878,236 (Direct)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
200,851 (Held by the Popovits 2010 Trust)
Shak StevenChief Scientific Officer2017-02-23Sell5,000331,103$29.36146.813.18331,103 (Direct)
Febbo Phillip G.Chief Medical Officer2017-02-16Sell2,49520,644$30.0975.0710.4420,644 (Direct)
Cole G BradleyCOO2017-02-15Sell5,00039,728$2914514.5939,728 (Direct)
Shak StevenChief Scientific Officer2017-01-23Sell5,000327,207$27.28136.421.81327,207 (Direct)
Cole G BradleyCOO2017-01-10Sell5,00035,882$29.22146.113.7235,882 (Direct)
Cole G BradleyCOO2016-12-06Sell5,00035,882$30.61153.058.5635,882 (Direct)
Popovits Kimberly JPresident and CEO2016-12-05Sell5,000289,594$30.02150.110.6959,620 (Direct)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
200,851 (Held by the Popovits 2010 Trust)
Leber LauraChief Communication Officer2016-11-21Sell7,06814,331$31.73224.274.7314,331 (Direct)
Shak StevenChief Scientific Officer2016-11-10Sell5,000327,207$31.71158.554.79327,207 (Direct)
Cole G BradleyCOO2016-11-08Sell5,00035,426$29.68148.411.9635,426 (Direct)
Popovits Kimberly JPresident and CEO2016-11-03Sell5,313289,594$28.88153.4415.0659,620 (Direct)
200,851 (Held by the Popovits 2010 Trust)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
Shak StevenChief Scientific Officer2016-10-11Sell5,000327,207$30.39151.959.35327,207 (Direct)
Cole G BradleyCOO2016-10-10Sell8,29035,426$30.59253.598.6335,426 (Direct)
Vaughn James JChief Commercial Officer2016-10-06Sell3,00026,079$29.6889.0411.9626,079 (Direct)
Shak StevenChief Scientific Officer2016-09-13Sell5,000327,207$26.83134.1523.85327,207 (Direct)
Cole G BradleyCOO2016-09-06Sell4,00035,426$27.41109.6421.2335,426 (Direct)
Shak StevenChief Scientific Officer2016-08-23Sell5,000327,207$27.24136.221.99327,207 (Direct)
BAKER FELIXDirector, 10% Owner2016-08-15Buy100,00011,841,478$27.02270222.98
318,623 (See footnote(,))
11,348,958 (See footnote(,,))
173,897 (See footnote(F1,))
Cole G BradleyCOO2016-08-11Sell5,00035,426$28.87144.3515.135,426 (Direct)
Vaughn James JChief Commercial Officer2016-08-08Sell3,00029,079$28.7486.2215.6229,079 (Direct)
Shak StevenChief Scientific Officer2016-07-19Sell5,000327,207$27.42137.121.19327,207 (Direct)
Cole G BradleyCOO2016-07-06Sell5,00035,426$26.64133.224.7435,426 (Direct)
Shak StevenChief Scientific Officer2016-06-21Sell5,000327,207$25.77128.8528.95327,207 (Direct)
Cole G BradleyCOO2016-06-09Sell5,00035,426$26.62133.124.8335,426 (Direct)
Vaughn James JChief Commercial Officer2016-06-06Sell1,99732,079$2855.9218.6832,079 (Direct)
Cole G BradleyCOO2016-05-16Sell5,00034,970$27.613820.434,970 (Direct)
Febbo Phillip G.Chief Medical Officer2016-05-10Sell6,32415,013$27.2172.0122.1715,013 (Direct)
Vaughn James JChief Commercial Officer2016-05-09Sell2,00031,255$285618.6831,255 (Direct)
Shak StevenChief Scientific Officer2016-05-04Sell10,000326,383$25.43254.330.67326,383 (Direct)
Vaughn James JChief Commercial Officer2016-02-09Sell324,076$280.0818.6824,076 (Direct)
LIVINGSTON RANDALL SDirector2016-01-13Sell1,2506,149$32.1440.183.396,149 (Direct)
Cole G BradleyCOO2016-01-12Sell4,00027,428$31.69126.764.8627,428 (Direct)
Vaughn James JChief Commercial Officer2016-01-07Sell2,00024,076$33.6367.26-1.1924,076 (Direct)
Cole G BradleyCOO2015-12-08Sell4,00027,428$29.26117.0413.5727,428 (Direct)
Leber LauraChief Communication Officer2015-12-07Sell4,20012,959$29.33123.1913.312,959 (Direct)
Vaughn James JChief Commercial Officer2015-12-07Sell2,00024,076$29.3358.6613.324,076 (Direct)
Cole G BradleyCOO2015-11-10Sell4,00030,326$26.03104.1227.6630,326 (Direct)
Cole G BradleyCOO2015-09-09Sell9,66430,326$25.35244.9831.0830,326 (Direct)
Cole G BradleyCOO2015-07-07Sell4,00030,326$27.53110.1220.730,326 (Direct)
Cole G BradleyCOO2015-06-09Sell4,00030,326$26.24104.9626.6430,326 (Direct)
Cole G BradleyCOO2015-05-12Sell4,00029,658$27.54110.1620.6629,658 (Direct)
Popovits Kimberly JPresident and CEO2015-04-13Sell3,000203,001$31.2893.846.23Link
Cole G BradleyCOO2015-04-07Sell4,00029,658$30.44121.769.1729,658 (Direct)
Popovits Kimberly JPresident and CEO2015-03-12Sell3,000204,101$31.9195.734.14Link
Cole G BradleyCOO2015-03-10Sell4,00029,658$31.84127.364.3729,658 (Direct)
Popovits Kimberly JPresident and CEO2015-02-12Sell3,000204,601$29.8689.5811.29Link
Cole G BradleyCOO2015-02-10Sell4,00021,645$31.37125.485.9321,645 (Direct)
LIVINGSTON RANDALL SDirector2015-02-02Sell1,0006,149$31.9331.934.076,149 (Direct)
Popovits Kimberly JPresident and CEO2015-01-12Sell3,000204,601$33.46100.38-0.69Link
Popovits Kimberly JPresident and CEO2014-12-11Sell3,000204,601$32.9998.970.73Link
Cole G BradleyCOO2014-12-08Sell4,33621,645$32.52141.012.1821,645 (Direct)
Popovits Kimberly JPresident and CEO2014-11-12Sell4,300205,201$34.82149.73-4.57Link
Cole G BradleyCOO2014-11-10Sell4,00022,891$35.35141.4-622,891 (Direct)
LIVINGSTON RANDALL SDirector2014-11-03Sell3,0006,149$36.24108.72-8.316,149 (Direct)
Popovits Kimberly JPresident and CEO2014-10-13Sell3,000205,201$30.7892.347.96Link
Cole G BradleyCOO2014-10-08Sell4,00022,891$28.77115.0815.522,891 (Direct)
Popovits Kimberly JPresident and CEO2014-09-11Sell3,000205,201$29.8289.4611.44Link
Cole G BradleyCOO2014-09-08Sell4,70022,891$30.09141.4210.4422,891 (Direct)
Shak StevenEVP of R&D2014-08-14Sell13,348312,298$27.36365.221.45312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-08-12Sell3,000205,201$26.0778.2127.46Link
Popovits Kimberly JPresident and CEO2014-07-14Sell3,000205,201$26.5979.7724.97Link
Cole G BradleyCOO2014-07-08Sell2,30022,891$27.0562.2222.8522,891 (Direct)
Shak StevenEVP of R&D2014-07-01Sell7,000312,298$2718923.07312,298 (Direct)
Shak StevenEVP of R&D2014-06-12Sell7,000312,298$26.73187.1124.32312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-06-12Sell3,000271,289$26.178.327.32Link
Schorno Dean LCFO2014-06-10Sell4,00030,673$27.62110.4820.3124,524 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2014-06-09Sell2,33722,891$27.2963.7821.7722,891 (Direct)
Popovits Kimberly JPresident and CEO2014-05-12Sell3,000270,579$26.5479.6225.21Link
Schorno Dean LCFO2014-05-09Sell4,00029,963$25.09100.3632.4423,814 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Shak StevenEVP of R&D2014-04-14Sell7,000311,588$26.25183.7526.59311,588 (Direct)
Cole G BradleyCOO2014-04-08Sell3,00022,226$278123.0722,226 (Direct)
Shak StevenEVP of R&D2014-03-14Sell7,000311,588$28.36198.5217.17311,588 (Direct)
Cole G BradleyCOO2014-03-10Sell3,00022,226$27.7683.2819.722,226 (Direct)
HIBBS KATHY LSVP & General Counsel2014-02-18Sell1,31215,787$27.8836.5819.1915,787 (Direct)
Shak StevenEVP of R&D2014-02-14Sell7,000311,588$27.38191.6621.37311,588 (Direct)
Cole G BradleyCOO2014-02-10Sell3,00024,789$278123.0724,789 (Direct)
Shak StevenEVP of R&D2014-01-15Sell7,000308,283$31.51220.575.46308,283 (Direct)
Popovits Kimberly JPresident and CEO2014-01-13Sell2,500261,190$307510.77Link
Cole G BradleyCOO2014-01-08Sell3,00018,369$28.1784.5117.9618,369 (Direct)
Shak StevenEVP of R&D & CMO2013-12-17Sell14,000308,283$29.57413.9812.38308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-12-12Sell2,5000$30.6876.78.31Link
Schorno Dean LCFO2013-12-09Sell3,00027,706$33.2599.75-0.0621,557 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-12-02Sell1,0006,149$34.9234.92-4.846,149 (Direct)
Popovits Kimberly JPresident and CEO2013-11-13Sell5,0000$34.58172.9-3.9Link
Schorno Dean LCFO2013-11-08Sell3,00027,585$33.36100.08-0.3921,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-11-06Sell2,86818,135$31.38905.918,135 (Direct)
Shak StevenEVP of R&D & CMO2013-10-15Sell5,000308,283$29.67148.3512308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-10-10Sell2,5000$307510.77Link
Cole G BradleyCOO2013-10-09Sell2,50018,135$29.9574.8810.9518,135 (Direct)
Shak StevenEVP of R&D & CMO2013-09-18Sell5,000313,283$33.73168.65-1.48313,283 (Direct)
Popovits Kimberly JPresident and CEO2013-09-12Sell2,5000$34.3185.78-3.15Link
Cole G BradleyCOO2013-09-09Sell2,50018,135$32.5381.332.1518,135 (Direct)
Schorno Dean LCFO2013-09-06Sell4,00027,585$32.9131.6121,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-09-03Sell1,0006,149$31.4931.495.536,149 (Direct)
Shak StevenEVP of R&D & CMO2013-08-14Sell5,000318,283$32.98164.90.76318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-08-12Sell2,5000$33.0382.580.61Link
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.60.2421,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.60.2421,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-08-07Sell2,50019,135$33.6684.15-1.2819,135 (Direct)
Shak StevenEVP of R&D & CMO2013-07-23Sell5,000318,283$35.33176.65-5.94318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-07-12Sell5,0000$34.61173.05-3.99Link
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.24-1.7217,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.24-1.7217,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-07-08Sell2,50013,135$33.3383.33-0.313,135 (Direct)
Shak StevenEVP of R&D & CMO2013-06-18Sell5,000323,283$33.52167.6-0.87323,283 (Direct)
Popovits Kimberly JPresident and CEO2013-06-12Sell5,0000$35.68178.4-6.87Link
Schorno Dean LCFO2013-06-10Sell4,00023,985$35.88143.52-7.3917,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-06-05Sell2,50013,135$36.4791.18-8.8813,135 (Direct)
BAKER FELIXDirector, 10% Owner2013-06-05Buy381,43213,288,253$36.1613792.58-8.1
1,730,777 (See Footnote)
11,241,654 (See Footnotes(F7,F14,F15))
301,215 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-06-03Buy179,58312,906,821$36.716592.49-9.48
1,690,226 (See Footnote)
10,909,066 (See Footnotes(F7,F14,F15))
292,922 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-06-03Sell1,0006,149$36.436.4-8.716,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-29Buy121,26612,727,238$36.894473.5-9.92
1,671,081 (See Footnote)
10,752,532 (See Footnotes(F7,F14,F15))
289,018 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-05-24Buy79,41714,257,273$36.932932.87-10.02
1,651,301 (See Footnote)
10,646,920 (See Footnotes(F7,F17,F18))
286,384 (See Footnotes(F9,F17,F18))
1,658,061 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-22Sell1,0007,087$37.4837.48-11.347,087 (Direct)
Shak StevenEVP of R&D & CMO2013-05-21Sell5,000327,380$37.19185.95-10.65327,380 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-16Buy71,43912,526,555$36.452603.95-8.83
1,649,473 (See Footnote)
10,577,816 (See Footnotes(F7,F14,F15))
284,659 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-05-15Sell1,3376,149$35.8347.9-7.266,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-14Buy240,42614,093,759$34.348256.23-3.23
1,638,643 (See Footnote)
10,515,769 (See Footnotes(F7,F17,F18))
283,112 (See Footnotes(F9,F17,F18))
1,641,628 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-13Sell1,2507,087$34.4243.03-3.467,087 (Direct)
Popovits Kimberly JPresident and CEO2013-05-13Sell5,0000$34.7173.5-4.24Link
Schorno Dean LCFO2013-05-09Sell4,00023,241$36.02144.08-7.7517,092 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-05-08Sell2,50012,540$35.9989.98-7.6712,540 (Direct)
Popovits Kimberly JPresident and CEO2013-04-23Sell2,5000$307510.77Link
Cole G BradleyCOO2013-04-03Sell2,50012,540$27.7969.4819.5812,540 (Direct)
Cole G BradleyCOO2013-03-06Sell2,50012,540$28.5771.4316.3112,540 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-21Buy49,08512,211,834$27.781363.5819.62
1,614,513 (See Footnote)
10,306,239 (See Footnotes(F7,F14,F15))
277,189 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
HIBBS KATHY LSVP & General Counsel2013-02-20Sell2,7167,087$28.1376.418.137,087 (Direct)
MYERS WOODROW A JRDirector2013-02-14Sell41,2502,891$28.41171.517.012,891 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-14Buy52,00012,162,749$28.481480.9616.68
1,609,152 (See Footnote)
10,263,580 (See Footnotes(F7,F14,F15))
276,124 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-02-11Buy116,36012,110,749$28.153275.5318.05
1,603,265 (See Footnote)
10,218,600 (See Footnotes(F7,F14,F15))
274,991 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-02-06Sell2,50014,085$28.0370.0818.5514,085 (Direct)
LIVINGSTON RANDALL SDirector2013-01-28Sell2,0006,149$28.7757.5415.56,149 (Direct)
Schorno Dean LCFO2013-01-09Sell2,62523,504$2873.518.6817,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-01-09Sell2,50014,085$27.8869.719.1914,085 (Direct)
Shak StevenEVP of R&D & CMO2012-12-18Sell5,000333,768$27.74138.719.79333,768 (Direct)
Popovits Kimberly JPresident and CEO2012-12-13Sell5,0000$27.79138.9519.58Link
Schorno Dean LCFO2012-12-11Sell3,00023,504$288418.6817,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2012-11-26Sell2,0006,149$27.8455.6819.366,149 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-21Buy229,30012,263,857$26.836152.1223.85288 (Direct)
271,800 (See Footnote)
1,589,551 (See Footnotes(F5,F14,F15))
10,117,174 (See Footnotes(F7,F14,F15))
271,806 (See Footnotes(F9,F14,F15))
13,238 (See Footnote(F9,F14,F15))
Shak StevenEVP of R&D & CMO2012-11-20Sell5,000338,768$26.94134.723.35338,768 (Direct)
COLELLA SAMUEL DDirector2012-11-20Sell30,61636,437$26.89823.2623.5836,437 (Direct)
0 (Versant Venture Capital I, L.P.)
0 (Versant Side Fund I, L.P.)
0 (Versant Affiliates Fund I-A, L.P.)
0 (Versant Affiliates Fund I-B, L.P.)
BAKER FELIXDirector, 10% Owner2012-11-14Buy103,16713,526$27.322818.5221.63288 (Direct)
13,238 (See Footnote)
Popovits Kimberly JPresident and CEO2012-11-14Sell5,0000$27.24136.221.99Link
BAKER FELIXDirector, 10% Owner2012-11-13Buy823,77213,526$27.8122909.119.49288 (Direct)
13,238 (See Footnote)
Schorno Dean LCFO2012-11-12Sell3,00023,504$288418.6817,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-11-08Sell2,50014,085$28.6271.5516.1114,085 (Direct)
Popovits Kimberly JPresident and CEO2012-10-16Sell10,0000$33.08330.80.45Link
Shak StevenEVP of R&D & CMO2012-10-16Sell5,000343,768$35.25176.25-5.73343,768 (Direct)
Schorno Dean LCFO2012-10-12Sell3,00023,504$33.79101.37-1.6617,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
HIBBS KATHY LSVP & General Counsel2012-10-11Sell1,25011,367$33.7842.23-1.6311,367 (Direct)
Cole G BradleyCOO2012-10-09Sell2,50014,085$34.887-4.5114,085 (Direct)
Shak StevenEVP of R&D & CMO2012-09-18Sell5,000348,768$33.76168.8-1.57348,768 (Direct)
Popovits Kimberly JPresident and CEO2012-09-13Sell5,0000$31.69158.454.86Link
Cole G BradleyCOO2012-09-06Sell2,50014,085$35.0187.53-5.0814,085 (Direct)
MYERS WOODROW A JRDirector2012-08-21Sell16,5002,236$35.2580.8-5.62,236 (Direct)
Shak StevenEVP of R&D & CMO2012-08-20Sell5,000353,768$34.99174.95-5.03353,768 (Direct)
Popovits Kimberly JPresident and CEO2012-08-13Sell10,0000$34.72347.2-4.29Link
Cole G BradleyCOO2012-08-08Sell2,50014,085$30.4976.238.9914,085 (Direct)
LIVINGSTON RANDALL SDirector2012-07-26Sell2,0006,149$35.971.8-7.446,149 (Direct)
Shak StevenChief Medical Officer2012-07-24Sell5,000358,768$34.24171.2-2.95358,768 (Direct)
Popovits Kimberly JPresident and CEO2012-07-13Sell7,1000$34.76246.8-4.4Link
Scott Randal WCEO, InVitae Corporation*2012-07-11Sell30,0000$35.391061.7-6.1Link
Cole G BradleyCOO2012-07-05Sell2,50014,085$35.9589.88-7.5714,085 (Direct)
Shak StevenChief Medical Officer2012-06-25Sell5,000363,768$33.25166.25-0.06363,768 (Direct)
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-0.39Link
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-0.39Link
Scott Randal WCEO, InVitae Corporation*2012-06-12Sell30,0000$33.541006.2-0.92Link
Cole G BradleyCOO2012-06-06Sell2,50013,507$33.9784.93-2.1813,507 (Direct)
Shak StevenChief Medical Officer2012-05-24Sell5,000367,849$33.8169-1.69367,849 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-22Buy167,4061,488,539$32.265400.523.01
1,488,539 (See Footnote)
COLELLA SAMUEL DDirector2012-05-18Sell26,294664,113$33.03868.490.6126,891 (Direct)
582,174 (Versant Venture Capital I, L.P.)
11,210 (Versant Side Fund I, L.P.)
13,222 (Colella Family Partners, L.P.)
10,414 (Versant Affiliates Fund I-A, L.P.)
20,202 (Versant Affiliates Fund I-B, L.P.)
BAKER JULIANDirector, 10% Owner2012-05-16Buy376,0591,488,539$33.8812740.88-1.92
1,488,539 (See Footnote)
Popovits Kimberly JPresident and CEO2012-05-16Sell10,0000$34.23342.3-2.92Link
Schorno Dean LCFO2012-05-15Sell1,00023,504$33.6933.69-1.3717,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER JULIANDirector, 10% Owner2012-05-11Buy114,8881,488,539$29.963442.0410.91
1,488,539 (See Footnote)
Scott Randal WCEO, InVitae Corporation*2012-05-11Sell30,0000$30.22906.69.96Link
Cole G BradleyCOO2012-05-09Sell2,50013,507$28.8772.1815.113,507 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-08Buy195,70113,238$28.455567.6916.8
13,238 (See Footnote)
LIVINGSTON RANDALL SDirector2012-04-26Sell2,0006,149$28.2156.4217.86,149 (Direct)
Shak StevenChief Medical Officer2012-04-24Sell5,000372,849$27.93139.6518.98372,849 (Direct)
Popovits Kimberly JPresident and CEO2012-04-23Sell5,0000$27.79138.9519.58Link
Schorno Dean LCFO2012-04-16Sell1,00024,504$27.9827.9818.7618,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation*2012-04-11Sell20,0000$28.59571.816.23Link
Cole G BradleyCOO2012-04-04Sell2,50013,507$30.2875.79.7413,507 (Direct)
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.410.47377,849 (Direct)
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.3510.51Link
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.3510.51Link
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.410.47377,849 (Direct)
Schorno Dean LCFO2012-03-15Sell1,00025,504$31.0831.086.9219,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation2012-03-13Sell30,0000$31.05931.57.02Link
Cole G BradleyCOO2012-03-08Sell2,50013,507$29.9474.8510.9913,507 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-08Buy4,5081,484,977$30.11135.7410.36
1,484,977 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-08Buy1,099227,840$30.1133.0910.36
227,840 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-08Buy41,5848,255,421$30.111252.0910.36
8,255,421 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-05Buy261,7618,213,837$29.817803.111.47
8,213,837 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-05Buy6,923226,741$29.81206.3711.47
226,741 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-05Buy31,3321,480,469$29.81934.0111.47
1,480,469 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-29Buy6,476219,818$29.06188.1914.35
219,818 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-29Buy245,0317,952,076$29.067120.614.35
7,952,076 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-29Buy29,7561,449,137$29.06864.7114.35
1,449,137 (Through Partnership)
Popovits Kimberly JPresident and CEO2012-02-24Sell10,0000$28.528516.6Link
Shak StevenChief Medical Officer2012-02-23Sell5,000382,849$28.14140.718.09382,849 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-23Buy114,5187,707,045$28.063213.3818.42
7,707,045 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-23Buy3,022213,342$28.0684.818.42
213,342 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-23Buy13,3321,419,381$28.06374.118.42
1,419,381 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-16Buy33,1851,406,049$29.34973.6513.26
1,406,049 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-16Buy7,213210,320$29.37211.8513.14
210,320 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-16Buy272,9097,592,527$29.378015.3413.14
7,592,527 (Through Partnership)
Schorno Dean LCFO2012-02-15Sell1,00026,504$28.7628.7615.5420,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2012-02-15Sell75526,749$28.7621.7115.5420,600 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.626.93Link
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-10Buy417,9157,319,618$26.3611016.2426.06
7,319,618 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-10Buy11,043203,107$26.36291.0926.06
203,107 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-10Buy66,5831,372,864$26.361755.1326.06
1,372,864 (Through Partnership)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.626.93Link
Cole G BradleyCOO2012-02-08Sell2,50014,450$26.4766.1825.5414,450 (Direct)
LIVINGSTON RANDALL SDirector2012-01-26Sell2,0006,149$27.5155.0220.796,149 (Direct)
Popovits Kimberly JPresident and CEO2012-01-25Sell5,0000$26.42132.125.78Link
Popovits Kimberly JPresident and CEO2012-01-24Sell5,0000$26.62133.124.83Link
Shak StevenChief Medical Officer2012-01-24Sell5,000382,778$26.74133.724.27382,778 (Direct)
Schorno Dean LCFO2012-01-17Sell1,00024,049$282818.6817,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-01-12Sell2,5007,750$27.5468.8520.667,750 (Direct)
Scott Randal WExecutive Chairman2012-01-11Sell20,0000$27.46549.221.01Link
Shak StevenChief Medical Officer2011-12-22Sell5,000387,778$26.03130.1527.66387,778 (Direct)
Scott Randal WExecutive Chairman2011-12-13Sell20,0000$27.29545.821.77Link
Cole G BradleyCOO2011-12-06Sell2,5007,750$28.5971.4816.237,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-12-05Buy3,152192,064$28.1288.6318.17
192,064 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-12-05Buy45,9771,306,281$27.661271.7220.14
1,306,281 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-12-05Buy117,7516,901,703$28.123311.1618.17
6,901,703 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-23Buy5,5311,260,304$25.91143.3128.25
1,260,304 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-23Buy5,750188,912$25.94149.1628.1
188,912 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-23Buy193,7396,783,952$25.915019.7828.25
6,783,952 (Through Partnership)
Shak StevenChief Medical Officer2011-11-22Sell5,000392,778$26.07130.3527.46392,778 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-16Buy64,5976,590,213$27.711789.9819.92
6,590,213 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-16Buy2,550183,162$27.7170.6619.92
183,162 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-16Buy4581,254,773$27.3512.5321.5
1,254,773 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-14Buy10,106180,612$27.23275.1922.03
180,612 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-14Buy249,3756,525,616$27.236790.4822.03
6,525,616 (Through Partnership)
Scott Randal WExecutive Chairman2011-11-11Sell20,0000$27.24544.821.99Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-09Buy5421,254,315$26.7914.5224.04
1,254,315 (Through Partnership)
Cole G BradleyCOO2011-11-08Sell2,5007,750$26.666.524.927,750 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-07Buy209,5126,276,241$25.945434.7428.1
6,276,241 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-07Buy8,847170,506$25.94229.4928.1
170,506 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-03Buy1201,253,773$24.482.9435.74
1,253,773 (Through Partnership)
LIVINGSTON RANDALL SDirector2011-10-27Sell2,0006,149$22.0844.1650.56,149 (Direct)
Shak StevenChief Medical Officer2011-10-24Sell5,000392,778$21.76108.852.71392,778 (Direct)
Scott Randal WExecutive Chairman2011-10-11Sell20,0000$22.83456.645.55Link
Cole G BradleyCOO2011-10-06Sell5,0007,750$22.31111.5548.957,750 (Direct)
Scott Randal WExecutive Chairman2011-09-13Sell20,0000$20.81416.259.68Link
Cole G BradleyCOO2011-09-06Sell2,5007,750$22.0855.250.57,750 (Direct)
Shak StevenChief Medical Officer2011-08-24Sell5,000392,778$23.02115.144.35392,778 (Direct)
Scott Randal WExecutive Chairman2011-08-11Sell20,0000$24.44488.835.97Link
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.1531.557,750 (Direct)
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.1531.557,750 (Direct)
LIVINGSTON RANDALL SDirector2011-07-27Sell2,0006,149$26.4552.925.636,149 (Direct)
Shak StevenChief Medical Officer2011-07-25Sell5,000392,778$27.61138.0520.35392,778 (Direct)
Scott Randal WExecutive Chairman2011-07-12Sell20,0001,503,444$27.36547.221.451,491,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Cole G BradleyCOO2011-07-06Sell5,0007,750$27.74138.719.797,750 (Direct)
Shak StevenChief Medical Officer2011-06-23Sell5,000392,778$27.12135.622.53392,778 (Direct)
Schorno Dean LCFO2011-06-15Sell1,00025,049$25.9125.9128.2518,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-06-13Sell20,0001,523,444$25.69513.829.351,511,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-09Buy119194,415$26.193.1226.88
194,415 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-06-09Buy4,388161,659$26.19114.9226.88
161,659 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-09Buy203,6526,059,449$26.25335.6826.83
6,059,449 (Through Partnership)
Cole G BradleyCOO2011-06-06Sell2,5007,750$26.1865.4526.937,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-06-01Buy4,631157,271$27.34126.6121.54
157,271 (Through Partnership)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-01Buy112194,296$27.353.0621.5
194,296 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-01Buy181,6935,855,797$27.354969.321.5
5,855,797 (Through Partnership)
Shak StevenChief Medical Officer2011-05-25Sell5,000392,778$25.55127.7530.06392,778 (Direct)
Schorno Dean LCFO2011-05-12Sell1,00026,049$26.4826.4825.4919,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-05-11Sell20,0000$26.66533.224.64Link
Cole G BradleyCOO2011-05-09Sell2,5007,750$25.9364.8328.157,750 (Direct)
LIVINGSTON RANDALL SDirector2011-04-27Sell2,0000$26.0452.0827.61Link
Shak StevenChief Medical Officer2011-04-25Sell5,0000$25.38126.930.93Link
Popovits Kimberly JPresident and CEO2011-04-15Sell8,0000$25.49203.9230.36Link
Schorno Dean LCFO2011-04-14Sell1,0000$25.3225.3231.24Link
Scott Randal WExecutive Chairman2011-04-12Sell20,0000$25.96519.228Link
Cole G BradleyCOO2011-04-06Sell5,0000$26.91134.5523.49Link
Shak StevenChief Medical Officer2011-03-24Sell5,0000$24.45122.2535.91Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.3236.81Link
Schorno Dean LCFO2011-03-15Sell1,0000$23.7923.7939.68Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.3236.81Link
Scott Randal WExecutive Chairman2011-03-11Sell20,0000$25.62512.429.7Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-10Buy70,8560$26.031844.3827.66Link
Cole G BradleyCOO2011-03-08Sell2,5000$25.2363.0831.71Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-08Buy9,6480$25.06241.7832.6Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-08Buy349,5660$25.068760.1232.6Link
COLELLA SAMUEL DDirector2011-03-03Sell34,3200$25.45873.4430.57Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-02Buy160,3370$25.694119.0629.35Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-02Buy4,4260$25.69113.729.35Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-02-25Buy158,3550$23.393703.9242.07Link
14159 capital (GP), LLCDirector, 10% Owner2011-02-25Buy4,3700$23.39102.2142.07Link
Shak StevenChief Medical Officer2011-02-24Sell5,0000$23.27116.3542.8Link
Schorno Dean LCFO2011-02-15Sell1,0000$22.5122.5147.62Link
Popovits Kimberly JPresident and CEO2011-02-15Sell8,0000$22.51180.0847.62Link
Scott Randal WExecutive Chairman2011-02-11Sell20,0000$22.244449.68Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,0000$21.15169.257.12Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,000309,424$21.15169.257.12Link
Schorno Dean LCFO2011-01-13Sell1,27626,149$21.0626.8757.79Link
Scott Randal WExecutive Chairman2011-01-11Sell20,0001,642,410$21.73434.652.92Link
Cole G BradleyCOO2011-01-06Sell5,0001,000$22.13110.6550.16Link
Popovits Kimberly JPresident and CEO2010-12-16Sell8,000310,624$22.71181.6846.32Link
Scott Randal WExecutive Chairman2010-12-13Sell20,0001,696,410$22.46449.247.95Link
Cole G BradleyCOO & CFO2010-12-13Sell2,5001,000$22.6456.646.78Link
Popovits Kimberly JPresident and CEO2010-11-16Sell8,000310,624$17.514089.89Link
Cole G BradleyCOO & CFO2010-11-11Sell2,5001,000$18.0445.184.2Link
Scott Randal WExecutive Chairman2010-11-11Sell20,0001,666,410$18.27365.481.88Link
Scott Randal WExecutive Chairman2010-10-12Sell20,0001,686,410$13.95279138.21Link
Popovits Kimberly JPresident and CEO2010-09-15Sell7,734310,624$15.1116.78120.07Link
Scott Randal WExecutive Chairman2010-09-13Sell20,0001,706,410$14.87297.4123.47Link
Cole G BradleyCOO & CFO2010-09-13Sell2,5001,000$15.0137.53121.39Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-09Buy145134,196$14.812.15124.38Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-09Buy5,2614,934,990$14.8177.92124.38Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-02Buy65,4664,929,729$14.46946.64129.81Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-02Buy1,807134,051$14.4626.13129.81Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-30Buy3,415132,244$14.3749.07131.25Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-30Buy123,7114,864,263$14.371777.73131.25Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-23Buy150,4694,740,552$14.522184.81128.86Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-23Buy4,153128,829$14.5260.3128.86Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-18Buy530124,676$14.997.94121.68Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-18Buy19,1874,590,083$14.99287.61121.68Link
Popovits Kimberly JPresident and CEO2010-08-17Sell8,000288,116$15.07120.56120.5Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-13Buy2,924124,146$14.8543.42123.77Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-13Buy105,9104,570,896$14.851572.76123.77Link
Cole G BradleyCOO & CFO2010-08-12Sell2,5001,000$1537.5121.53Link
Scott Randal WExecutive Chairman2010-08-11Sell20,0001,726,410$14.71294.2125.9Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-10Buy164,2424,464,986$14.612399.58127.45Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-10Buy4,533121,222$14.6166.23127.45Link
Baker JoffreChief Scientific Officer2010-08-09Sell4,629163,088$14.7568.28125.29Link
Scott Randal WExecutive Chairman2010-07-13Sell20,0001,746,410$12.81256.2159.41Link
Baker JoffreChief Scientific Officer2010-07-07Sell4,629167,717$13.0560.41154.64Link
Scott Randal WExecutive Chairman2010-06-11Sell20,0001,766,410$14.15283134.84Link
Baker JoffreChief Scientific Officer2010-06-10Sell4,629172,346$14.0565.04136.51Link
Popovits Kimberly JPresident and CEO2010-05-17Sell8,000310,624$15.78126.24110.58Link
Cole G BradleyCOO & CFO2010-05-12Sell2,5001,000$15.8739.68109.39Link
Scott Randal WExecutive Chairman2010-05-11Sell20,0001,776,410$15.61312.2112.88Link
Baker JoffreChief Scientific Officer2010-05-10Sell4,629176,975$15.5171.8114.25Link
Scott Randal WExecutive Chairman2010-04-13Sell20,0001,796,410$16.87337.496.98Link
Cole G BradleyCOO & CFO2010-04-12Sell5,0001,000$16.984.596.63Link
Baker JoffreChief Scientific Officer2010-04-12Sell4,629181,604$16.8878.1496.86Link
Popovits Kimberly JPresident and CEO2010-03-16Sell20,000288,116$19.4538970.85Link
Scott Randal WExecutive Chairman2010-03-11Sell20,0001,800,646$19.338672.18Link
Cole G BradleyCOO & CFO2010-03-11Sell2,5001,000$19.3948.4871.38Link
COLELLA SAMUEL DDirector2010-03-10Sell106,70085,050$19.452075.3270.85Link
Baker JoffreChief Scientific Officer2010-03-08Sell4,629150,120$19.8391.7967.57Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-19Buy3,645116,689$17.0562.1594.9Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-19Buy132,0704,300,744$17.052251.7994.9Link
Scott Randal WExecutive Chairman2010-02-11Sell20,0001,830,646$17.23344.692.86Link
Cole G BradleyCOO & CFO2010-02-11Sell2,5001,000$17.5143.7889.78Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-10Buy9,437113,044$17.01160.5295.36Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-10Buy341,8544,168,674$17.015814.9495.36Link
Baker JoffreChief Scientific Officer2010-02-09Sell4,629145,491$17.1479.3493.87Link
Cole G BradleyCOO & CFO2010-01-12Sell5,0001,000$17.2586.2592.64Link
Baker JoffreChief Scientific Officer2010-01-11Sell4,629150,120$17.4780.8790.21Link
Shak StevenChief Medical Officer2009-12-21Sell5,000388,278$20.12100.665.16Link
Popovits Kimberly JPresident and CEO2009-12-15Sell5,000313,506$20.39101.9562.97Link
Cole G BradleyCOO & CFO2009-12-14Sell2,0001,000$20.4240.8462.73Link
Scott Randal WExecutive Chairman2009-12-11Sell12,0001,880,646$20.24242.8864.18Link
Baker JoffreChief Scientific Officer2009-12-08Sell4,629154,749$20.2693.7864.02Link
Popovits Kimberly JPresident and CEO2009-11-17Sell20,000318,506$19.21384.272.98Link
Cole G BradleyCOO & CFO2009-11-12Sell6653,000$20.0413.3365.82Link
Scott Randal WExecutive Chairman2009-11-11Sell12,0001,892,646$19.99239.8866.23Link
Baker JoffreChief Scientific Officer2009-11-10Sell4,629159,378$2092.5866.15Link
Shak StevenChief Medical Officer2009-10-20Sell5,000393,278$20.65103.2560.92Link
Popovits Kimberly JPresident and CEO2009-10-15Sell5,000338,506$20.42102.162.73Link
Scott Randal WExecutive Chairman2009-10-13Sell12,0001,904,646$20.66247.9260.84Link
Baker JoffreChief Scientific Officer2009-10-07Sell4,629164,007$21.179856.97Link
Shak StevenChief Medical Officer2009-09-22Sell5,000398,278$21.13105.6557.26Link
Popovits Kimberly JPresident and CEO2009-09-15Sell5,000343,506$20.73103.6560.3Link
Scott Randal WExecutive Chairman2009-09-11Sell12,0001,916,646$20.67248.0460.76Link
Baker JoffreChief Scientific Officer2009-09-04Sell4,629168,636$20.1293.1465.16Link
Shak StevenChief Medical Officer2009-08-25Sell5,000403,278$20.77103.8559.99Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-17Buy1,839103,607$19.9836.7466.32Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-17Buy66,6303,826,820$19.981331.2766.32Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-17Buy34194,184$19.980.6866.32Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-17Buy11,6571,253,653$19.98232.9166.32Link
Popovits Kimberly JPresident and CEO2009-08-17Sell5,000348,506$19.5397.6570.15Link
Cole G BradleyCOO & CFO2009-08-13Sell5,0003,000$2010066.15Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-12Buy15,8771,241,996$19.49309.4470.5Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-12Buy45194,150$19.50.8870.41Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-12Buy90,7543,760,190$19.491768.870.5Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-12Buy2,508101,768$19.4948.8870.5Link
Scott Randal WExecutive Chairman2009-08-11Sell12,0001,928,646$19.42233.0471.11Link
Baker JoffreChief Scientific Officer2009-08-10Sell4,629173,265$19.4890.1770.59Link
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.11107.56
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.11107.56
Scott Randal WExecutive Chairman2009-06-11Sell6,0001,940,646$18.27109.6281.88
Baker JoffreChief Scientific Officer2009-06-08Sell4,629182,523$17.6981.8987.85
Shak StevenChief Medical Officer2009-05-26Sell5,000408,278$199574.89
14159 capital (GP), LLCDirector, 10% Owner2009-05-21Buy1,10899,260$17.9719.9184.92
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-21Buy90194,161$17.971.6284.92
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-21Buy39,7783,669,436$17.97714.8184.92
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-21Buy25194,105$17.970.4584.92
Popovits Kimberly JPresident and CEO2009-05-15Sell5,000353,506$20.12100.665.16
Scott Randal WExecutive Chairman2009-05-12Sell12,0001,946,646$19.46233.5270.76
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-11Buy88194,080$19.551.7269.97
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-11Buy312194,071$19.556.169.97
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-11Buy137,4663,629,658$19.552687.4669.97
14159 capital (GP), LLCDirector, 10% Owner2009-05-11Buy3,82798,152$19.5574.8269.97
Baker JoffreChief Scientific Officer2009-05-08Sell4,629187,152$19.7291.2868.51
Scott Randal WExecutive Chairman2009-04-14Sell12,0001,958,646$25.47305.6430.47
Baker JoffreChief Scientific Officer2009-04-01Sell4,629191,781$25.27116.9731.5
Scott Randal WExecutive Chairman2009-03-11Sell12,0001,970,646$19.4232.871.29
Baker JoffreChief Scientific Officer2009-03-03Sell4,629196,410$19.1388.5573.71
Cole G BradleyCOO & CFO2009-02-17Sell5,0003,000$21.52107.654.41
Baker JoffreChief Scientific Officer2009-02-12Sell4,629201,039$20.695.3661.31
Baker JoffreChief Scientific Officer2009-02-12Sell4,62922,226$20.695.3661.31
Scott Randal WExecutive Chairman, Director2009-02-11Sell12,0001,982,646$20.85250.259.38
Baker JoffreChief Scientific Officer2009-01-12Sell4,62926,855$19.4189.8571.2
Shak StevenChief Medical Officer2008-12-22Sell100413,278$20.172.0264.75
Baker JoffreChief Scientific Officer2008-12-10Sell4,629205,668$19.2589.1172.62
Baker JoffreChief Scientific Officer2008-12-10Sell4,62931,484$19.2589.1172.62
Scott Randal WCEO, Director2008-12-09Sell12,0001,955,298$18.4220.880.6
Baker JoffreChief Scientific Officer2008-11-12Sell4,629210,297$19.8791.9867.24
Baker JoffreChief Scientific Officer2008-11-12Sell4,62936,113$19.8791.9867.24
Scott Randal WCEO, Director2008-11-11Sell12,0001,967,298$20.05240.665.74
Cole G BradleyEVP & CFO2008-11-10Sell10,0004,000$20.17201.764.75
Scott Randal WCEO, Director2008-10-14Sell12,0001,979,298$20.36244.3263.21
Baker JoffreChief Scientific Officer2008-10-01Sell9,25840,742$22.51208.447.62
Shak StevenChief Medical Officer2008-09-24Sell5,000413,378$22.67113.3546.58
Scott Randal WCEO, Director2008-09-16Sell12,0001,991,298$21.79261.4852.5
Shak StevenChief Medical Officer2008-08-26Sell5,000418,378$22.93114.6544.92
Baker JoffreChief Scientific Officer2008-08-26Sell4,629214,926$22.69105.0346.45
Cole G BradleyEVP & CFO2008-08-18Sell9,2984,000$23.67220.0840.39
Popovits Kimberly JPresident and COO2008-08-15Sell25,000358,506$24.2460637.09
Scott Randal WCEO, Director2008-08-12Sell12,0002,003,298$23.76285.1239.86
Scott Randal WCEO, Director2008-07-15Sell12,0002,015,298$2125258.24
Baker JoffreChief Scientific Officer2008-07-01Sell4,629219,555$19.2689.1572.53
Shak StevenChief Medical Officer2008-06-24Sell100423,378$20266.15
Scott Randal WCEO, Director2008-06-10Sell12,0002,027,298$19.92239.0466.82
Baker Brothers Life Sciences CDirector, 10% Owner2008-06-09Buy320,9833,492,192$19.916390.7766.9
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-06-09Buy76,0151,226,119$19.911513.4666.9
14159 capital (GP), LLCDirector, 10% Owner2008-06-09Buy10,29994,325$19.91205.0566.9
Baker JoffreChief Scientific Officer2008-06-02Sell4,629228,813$17.9983.2884.71
Scott Randal WCEO, Director2008-05-13Sell12,0002,039,298$18.7522577.23
Baker JoffreChief Scientific Officer2008-05-08Sell4,629233,442$19.2789.272.44
Scott Randal WCEO, Director2008-04-15Sell12,0002,051,298$17.22206.6492.97
Scott Randal WCEO, Director2008-03-11Sell12,0002,063,298$18.84226.0876.38
Baker JoffreChief Scientific Officer2008-03-05Sell4,629242,700$20.4894.862.26
Shak StevenChief Medical Officer2008-02-26Sell5,000423,478$20.23101.1564.26
Cole G BradleyEVP & CFO2008-02-19Sell9,0008,298$22.58203.2247.17
Scott Randal WCEO, Director2008-02-12Sell12,0002,075,298$23.01276.1244.42
Baker JoffreChief Scientific Officer2008-02-11Sell4,629247,329$22.94106.1944.86
Scott Randal WCEO, Director2008-01-15Sell12,0002,087,298$25.54306.4830.11
Baker JoffreChief Scientific Officer2008-01-02Sell4,629251,958$22.66104.8946.65
Baker JoffreChief Scientific Officer2007-12-03Sell4,6290$23.1106.9343.85
Popovits Kimberly JPresident and COO2007-11-27Sell6,655383,506$22146.4151.05
Scott Randal WCEO, Director2007-11-09Sell12,0002,111,299$23.07276.8444.04
Baker JoffreChief Scientific Officer2007-11-08Sell4,629265,845$23.21107.4443.17
Scott Randal WCEO2007-10-09Sell12,0002,123,299$20.16241.9264.83
Baker JoffreChief Scientific Officer2007-10-01Sell4,629270,474$19.8491.8467.49
Scott Randal WCEO, Director2007-09-11Sell12,0002,135,299$19.7236.468.68
Scott Randal WCEO2007-09-11Sell12,0002,135,299$19.69236.2868.77
Baker JoffreChief Scientific Officer2007-09-10Sell4,629275,103$19.5790.5969.8
Goldberg Michael DDirector2007-08-23Buy5,3505,350$18.76100.3777.13
Scott Randal WCEO2007-08-15Sell12,0002,147,299$19.91238.9266.9
Baker JoffreChief Scientific Officer2007-08-08Sell4,629279,732$19.4489.9970.94
Scott Randal WCEO2007-07-18Sell12,0002,159,299$21.18254.1656.89
Baker JoffreChief Scientific Officer2007-07-02Sell4,629284,361$19.018874.8
Scott Randal WCEO2007-06-19Sell12,0002,171,299$19.16229.9273.43
Baker JoffreChief Scientific Officer2007-06-01Sell4,629288,990$17.5681.2989.24
Baker Bros. Capital (GP), LLCDirector2007-05-30Buy545193,992$16.328.89103.62
Baker Biotech Capital (GP), LLDirector2007-05-30Buy81,1811,150,104$16.321324.87103.62
Baker Brothers Life Sciences CDirector2007-05-30Buy214,0993,171,209$16.323494.1103.62
14159 capital (GP), LLCDirector2007-05-30Buy6,80784,026$16.32111.09103.62
14159 capital (GP), LLCDirector2007-05-24Buy16,26177,219$16.59269.77100.3
Baker Brothers Life Sciences CDirector2007-05-24Buy511,5532,957,110$16.598486.66100.3
Baker Biotech Capital (GP), LLDirector2007-05-24Buy193,9661,068,923$16.593217.9100.3
Baker Bros. Capital (GP), LLCDirector2007-05-24Buy1,303193,447$16.5921.62100.3
14159 capital (GP), LLCDirector2007-05-21Buy22,49160,958$15.5348.61114.39
14159 capital (GP), LLCDirector2007-05-21Buy160,958$15.50.02114.39
Baker Brothers Life Sciences CDirector2007-05-21Buy707,4582,445,557$15.510965.6114.39
Baker Biotech Capital (GP), LLDirector2007-05-21Buy268,248874,957$15.54157.84114.39
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.95114.39
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.95114.39
Scott Randal WCEO2007-05-08Sell12,0002,183,299$16.62199.4499.94
Baker JoffreChief Scientific Officer2007-05-08Sell4,629293,619$16.3175.5103.74
Scott Randal WCEO2007-04-10Sell12,0002,195,299$17.27207.2492.41
Baker JoffreChief Scientific Officer2007-04-02Sell4,629298,248$17.1679.4393.65
Baker / Tisch Capital (GP), LLDirector2007-03-09Buy3,181193,759$18.2858.1581.78
Baker Bros. Capital (GP), LLCDirector2007-03-09Buy376190,341$18.286.8781.78
Baker Biotech Capital (GP), LLDirector2007-03-09Buy62,325606,709$18.281139.381.78
Baker Brothers Life Sciences CDirector2007-03-09Buy168,5601,738,099$18.283081.2881.78
14159 capital (GP), LLCDirector2007-03-09Buy5,37538,467$18.2898.2681.78
Scott Randal WCEO2007-03-06Sell12,0002,207,299$18.35220.281.09
Baker Bros. Capital (GP), LLCDirector2007-03-02Buy119189,965$18.092.1583.69
14159 capital (GP), LLCDirector2007-03-02Buy1,70733,092$18.0930.8883.69
Baker / Tisch Capital (GP), LLDirector2007-03-02Buy1,072190,578$18.119.483.59
Baker Biotech Capital (GP), LLDirector2007-03-02Buy19,795544,384$18.09358.0983.69
Baker Brothers Life Sciences CDirector2007-03-02Buy53,5331,569,539$18.09968.4183.69
Baker JoffreChief Scientific Officer2007-03-01Sell4,629302,877$18.1884.1682.78
MYERS WOODROW A JRDirector2007-02-21Buy2,00012,000$19.6339.2669.28
Baker Brothers Life Sciences CDirector2007-02-16Buy25,4121,516,006$18.54471.1479.23
Baker Biotech Capital (GP), LLDirector2007-02-16Buy9,396524,589$18.54174.279.23
Baker / Tisch Capital (GP), LLDirector2007-02-16Buy525189,506$18.549.7379.23
14159 capital (GP), LLCDirector2007-02-16Buy81131,385$18.5415.0479.23
Baker Bros. Capital (GP), LLCDirector2007-02-16Buy56189,846$18.541.0479.23
Baker Bros. Capital (GP), LLCDirector2007-02-14Buy579189,790$18.2510.5782.08
Baker / Tisch Capital (GP), LLDirector2007-02-14Buy5,346188,981$18.2597.5682.08
Baker Biotech Capital (GP), LLDirector2007-02-14Buy95,783515,193$18.251748.0482.08
14159 capital (GP), LLCDirector2007-02-14Buy8,25630,574$18.25150.6782.08
Baker Brothers Life Sciences CDirector2007-02-14Buy259,0441,490,594$18.254727.5582.08
Scott Randal WCEO2007-02-13Sell12,0002,219,299$18.12217.4483.39
Baker JoffreChief Scientific Officer2007-02-08Sell4,629307,506$18.9787.8175.17
Baker / Tisch Capital (GP), LLDirector2006-12-06Buy642183,635$21.5813.8553.99
Baker Brothers Life Sciences CDirector2006-12-06Buy34,1731,231,550$21.58737.4553.99
14159 capital (GP), LLCDirector2006-12-06Buy1,12022,318$21.5824.1753.99
Baker Biotech Capital (GP), LLDirector2006-12-06Buy12,237419,410$21.58264.0753.99
MYERS WOODROW A JRDirector2006-12-05Buy10,00010,000$21.97219.751.25
Baker / Tisch Capital (GP), LLDirector2006-12-05Buy9,096182,993$20.6187.3861.31
Baker Biotech Capital (GP), LLDirector2006-12-05Buy173,441407,173$20.63572.8861.31
14159 capital (GP), LLCDirector2006-12-05Buy15,88021,198$20.6327.1361.31
Baker Brothers Life Sciences CDirector2006-12-05Buy484,3331,197,377$20.69977.2661.31
14159 capital (GP), LLCDirector2006-09-08Buy5,3185,318$14.0574.72136.51Link
Baker Biotech Capital (GP), LLDirector2006-09-08Buy75,246233,732$14.051057.21136.51Link
Baker Brothers Life Sciences CDirector2006-09-08Buy237,236713,044$14.053333.17136.51Link
Baker Biotech Capital III (GP)10% Owner2005-10-04Buy136,316252,529$121635.79176.92Link
Baker Biotech Capital II (GP),10% Owner2005-10-04Buy38,684181,478$12464.21176.92Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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