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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Duliege Anne-MarieChief Medical Officer2017-01-03Sell5,0005,000$2.4112.0517.845,000 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2016-08-30Sell5,30353,031$421.21-29
53,031 (By Family Trust)
PAYAN DONALD GEVP, Pres. Discovery&Research2015-06-10Sell41,66658,334$3.68153.33-22.8358,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2015-04-01Sell10,00058,334$3.7537.5-24.2758,334 (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$2.222.2227.93575 (Direct)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2014-12-18Sell1,000575$2.222.2227.93575 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-09-03Sell20,00068,334$2.5651.210.9468,334 (Direct)
PAYAN DONALD GEVP, Pres. Discovery&Research2014-02-24Sell20,00088,334$3.7174.2-23.4588,334 (Direct)
BVF PARTNERS L P/IL10% Owner2013-11-19Sell484,6226,962,123$2.641279.47.58
6,962,123 (See Explanation of Responses)
BVF PARTNERS L P/IL10% Owner2013-06-07Buy32,7006,962,123$3.47113.47-18.16
6,962,123 (See Explanation of Responses)
VANCE DOLLYEVP Corp. Affairs, G.C., Sect.2012-09-13Sell4,1511,103$10.4343.29-72.771,103 (Direct)
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-09-12Sell23,3020$10.67248.63-73.38Link
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-09-10Sell51,6980$10.54544.9-73.06Link
Maynard Ryan DEVP & CFO
(Click for the stocks that their CFOs have bought)
2012-08-07Sell1,7000$10.6118.04-73.23Link
PAYAN DONALD GEVP, Pres. Discovery&Research2012-06-19Sell10,000108,334$8.787-67.36108,334 (Direct)
Flynn James E2011-05-26Buy650,0006,742,289$85200-64.525,000 (Direct)
470,425 (Through Deerfield Special Situations Fund, L.P.)
762,700 (Through Deerfield Special Situations Fund International Limited)
2,279,997 (Through Deerfield Partners, L.P.)
3,204,167 (Through Deerfield International Limited)
Flynn James E2010-11-03Sell7,7116,092,289$7.5558.22-62.38Link
Goodwin Bradford SDirector2007-08-09Buy10,00010,000$9.9399.3-71.4
Grossbard Elliott BSr. VP Medical Development2007-05-29Buy2,0002,000$9.6819.36-70.66
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2005-12-07Buy1,0009,000$8.128.12-65.02Link
DELEAGE JEANDirector2005-07-27Sell171,99711,604$20.333496.7-86.03Link
DELEAGE JEANDirector2005-07-25Sell6,40017,707$20.37130.37-86.06Link
DELEAGE JEANDirector2005-07-21Sell58617,934$20.7512.16-86.31Link
DELEAGE JEANDirector2005-07-20Sell148,04317,955$20.753071.89-86.31Link
VANCE DOLLYVP Intel. Prop.& Gen.Counsel2005-05-10Sell15,0004,385$19.71295.65-85.59Link
VANCE DOLLYVP Intel. Prop.& Gen.Counsel2005-03-30Buy1,0004,385$15.9915.99-82.24Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2005-02-08Buy5008,000$18.789.39-84.88Link
FRAZIER ALAN DDirector2005-01-25Sell2,33210,905$19.144.54-85.13Link
HENNER DENNISDirector2005-01-05Sell17,2530$23.26401.3-87.79Link
HENNER DENNISDirector2004-11-23Sell868,05517,253$23.4920390.61-87.91Link
SIMON NICHOLAS J IIIDirector2004-11-23Sell868,0550$23.4920390.61-87.91Link
DELEAGE JEANDirector2004-11-05Sell126,05023,207$26.113291.17-89.12Link
DELEAGE JEANDirector2004-10-21Sell177,60027,680$25.054448.88-88.66Link
DELEAGE JEANDirector2004-10-19Sell46,35033,981$26.291218.54-89.2Link
DELEAGE JEANDirector2004-09-30Sell25,6250$24.79635.24-88.54Link
SIMON NICHOLAS J IIIDirector2004-09-17Sell14,9560$32.33483.53-91.22Link
WELCH JAMES HCFO, VP & Secretary
(Click for the stocks that their CFOs have bought)
2004-09-02Sell10,0003,757$20.23202.3-85.96Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-09-01Sell85,0271,687,072$20.751764.31-86.31Link
HENNER DENNISDirector, 10% Owner2004-09-01Sell85,0271,688,641$20.751764.31-86.31Link
EVNIN LUKE10% Owner2004-09-01Sell85,8531,687,072$20.741780.59-86.31Link
MPM BIOVENTURES III QP LP10% Owner2004-09-01Sell85,8531,687,072$20.741780.59-86.31Link
RODRIGUEZ RAUL REVP, COO2004-08-31Sell11,00023,607$20.85229.35-86.38Link
HENNER DENNISDirector, 10% Owner2004-08-20Sell32,4991,773,668$21.83709.45-86.99Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-20Sell33,4211,772,099$21.83729.58-86.99Link
EVNIN LUKE10% Owner2004-08-20Sell32,4991,772,925$21.83709.45-86.99Link
MPM BIOVENTURES III QP LP10% Owner2004-08-20Sell32,4991,772,925$21.83709.45-86.99Link
EVNIN LUKE10% Owner2004-08-18Sell18,9991,805,424$22.26422.92-87.24Link
HENNER DENNISDirector, 10% Owner2004-08-18Sell18,9991,806,167$22.26422.92-87.24Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-18Sell18,9991,805,520$22.26422.92-87.24Link
MPM BIOVENTURES III QP LP10% Owner2004-08-18Sell18,9991,805,424$22.26422.92-87.24Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-08-13Sell10,0001,824,519$22.3223-87.26Link
EVNIN LUKE10% Owner2004-08-13Sell10,0001,824,423$22.3223-87.26Link
MPM BIOVENTURES III QP LP10% Owner2004-08-13Sell10,0001,824,423$22.3223-87.26Link
HENNER DENNISDirector, 10% Owner2004-08-13Sell10,0001,825,166$22.3223-87.26Link
STEINMETZ MICHAEL10% Owner2004-08-02Sell1,9681,833,597$18.6836.76-84.8Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2004-07-16Buy2,5007,500$11.4628.65-75.22Link
EVNIN LUKE10% Owner2004-07-02Sell7,8471,833,597$14.88116.76-80.91Link
GALAKATOS NICHOLAS10% Owner2004-07-02Sell1,6521,833,597$15.3325.33-81.47Link
GADICKE ANSBERT10% Owner2004-07-02Sell2,4631,833,597$14.5935.94-80.53Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-28Sell2,8771,834,519$15.8345.54-82.06Link
HENNER DENNISDirector, 10% Owner2004-06-28Sell2,8771,835,166$15.8345.54-82.06Link
MPM BIOVENTURES III QP LP10% Owner2004-06-28Sell2,8771,849,800$15.8345.54-82.06Link
EVNIN LUKE10% Owner2004-06-28Sell2,8771,849,800$15.8345.54-82.06Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-81.86Link
MPM BIOVENTURES III QP LP10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-81.86Link
HENNER DENNISDirector, 10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-81.86Link
EVNIN LUKE10% Owner2004-06-25Sell124,3073,336,463$15.661946.65-81.86Link
MPM BIOVENTURES III QP LP10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-81.69Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-81.69Link
HENNER DENNISDirector, 10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-81.69Link
EVNIN LUKE10% Owner2004-06-23Sell30,1933,460,770$15.51468.29-81.69Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-02Sell2,0303,490,963$1836.54-84.22Link
MPM BIOVENTURES III QP LP10% Owner2004-06-02Sell2,0303,490,963$1836.54-84.22Link
HENNER DENNISDirector, 10% Owner2004-06-02Sell2,0303,490,963$1836.54-84.22Link
EVNIN LUKE10% Owner2004-06-02Sell2,0303,490,963$1836.54-84.22Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-84.19Link
MPM BIOVENTURES III QP LP10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-84.19Link
HENNER DENNISDirector, 10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-84.19Link
EVNIN LUKE10% Owner2004-06-01Sell13,9503,492,993$17.96250.54-84.19Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-84.08Link
MPM BIOVENTURES III QP LP10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-84.08Link
HENNER DENNISDirector, 10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-84.08Link
EVNIN LUKE10% Owner2004-05-27Sell26,0153,506,943$17.84464.11-84.08Link
EVNIN LUKE10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-83.63Link
HENNER DENNISDirector, 10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-83.63Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-83.63Link
MPM BIOVENTURES III QP LP10% Owner2004-05-24Sell3,3003,532,958$17.3557.26-83.63Link
COOPER ROBIN D GSr. V.P. Pharmaceutical Scs.2004-05-21Buy5,0005,000$16.6783.35-82.96Link
FRAZIER ALAN DDirector2004-05-20Sell2,333949,280$17.6141.08-83.87Link
HENNER DENNISDirector, 10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-83.54Link
EVNIN LUKE10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-83.54Link
MPM BIOVENTURES III QP LP10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-83.54Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-05-20Sell139,3133,536,258$17.252403.15-83.54Link
DELEAGE JEANDirector, 10% Owner2004-05-07Sell3,10044,573$21.566.65-86.79Link
ALTA PARTNERS II INC10% Owner2004-05-07Sell3,10044,573$21.566.65-86.79Link
ALTA PARTNERS II INC10% Owner2004-05-03Sell95,20044,573$21.312028.71-86.67Link
DELEAGE JEANDirector, 10% Owner2004-05-03Sell95,20044,573$21.312028.71-86.67Link
DELEAGE JEANDirector, 10% Owner2004-04-30Sell8,40044,573$21.25178.5-86.64Link
ALTA PARTNERS II INC10% Owner2004-04-30Sell8,40044,573$21.25178.5-86.64Link
DELEAGE JEANDirector, 10% Owner2004-04-29Sell42,80044,573$21.25909.5-86.64Link
ALTA PARTNERS II INC10% Owner2004-04-29Sell42,80055,006$21.25909.5-86.64Link
DELEAGE JEANDirector, 10% Owner2004-04-27Sell8,90044,573$21.26189.21-86.64Link
ALTA PARTNERS II INC10% Owner2004-04-27Sell8,90055,962$21.26189.21-86.64Link
DELEAGE JEANDirector, 10% Owner2004-04-23Sell13,10044,573$21.32279.29-86.68Link
ALTA PARTNERS II INC10% Owner2004-04-23Sell13,10044,573$21.32279.29-86.68Link
ALTA PARTNERS II INC10% Owner2004-04-22Sell8,80056,454$21.26187.09-86.64Link
DELEAGE JEANDirector, 10% Owner2004-04-22Sell8,80056,454$21.26187.09-86.64Link
EVNIN LUKE10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-86.29Link
MPM BIOVENTURES III QP LP10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-86.29Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-86.29Link
HENNER DENNISDirector, 10% Owner2004-04-21Sell158,6983,675,571$20.713286.64-86.29Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-85.75Link
EVNIN LUKE10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-85.75Link
MPM BIOVENTURES III QP LP10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-85.75Link
HENNER DENNISDirector, 10% Owner2004-04-12Sell316,3023,834,269$19.936303.9-85.75Link
DELEAGE JEANDirector, 10% Owner2004-04-07Sell60,30044,573$211266.3-86.48Link
ALTA PARTNERS II INC10% Owner2004-04-07Sell60,30044,573$211266.3-86.48Link
DELEAGE JEANDirector, 10% Owner2004-04-06Sell10,90057,997$21.21231.19-86.61Link
ALTA PARTNERS II INC10% Owner2004-04-06Sell10,90044,573$21.21231.19-86.61Link
FRAZIER ALAN DDirector2004-04-05Sell2,5241,409,965$22.7657.45-87.52Link
ALTA PARTNERS II INC10% Owner2004-03-24Sell7,48744,573$20149.74-85.8Link
DELEAGE JEANDirector, 10% Owner2004-03-24Sell7,48744,573$20149.74-85.8Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-03-19Sell17,3344,150,571$20346.68-85.8Link
HENNER DENNISDirector, 10% Owner2004-03-19Sell17,3344,150,571$20346.68-85.8Link
MPM BIOVENTURES III QP LP10% Owner2004-03-19Sell17,3344,150,571$20346.68-85.8Link
EVNIN LUKE10% Owner2004-02-19Sell17,3344,150,571$20346.68-85.8Link
FRAZIER HEALTHCARE IV LP10% Owner2004-02-19Sell78,4361,223,647$18.81474.6-84.89Link
FRAZIER ALAN DDirector, 10% Owner2004-02-19Sell78,4361,706,726$18.81474.6-84.89Link
SIMON NICHOLAS J IIIDirector, 10% Owner2004-02-19Sell172,3734,167,905$203447.46-85.8Link
HENNER DENNISDirector, 10% Owner2004-02-19Sell172,3734,167,905$203447.46-85.8Link
MPM BIOVENTURES III QP LP10% Owner2004-02-19Sell172,3734,350,516$203447.46-85.8Link
MPM BIOEQUITIES MASTER FUND LP10% Owner2004-02-19Sell172,3734,350,516$203447.46-85.8Link
ALTA PARTNERS II INC10% Owner2004-02-19Sell111,69644,573$202233.92-85.8Link
DELEAGE JEANDirector, 10% Owner2004-02-19Sell111,69644,573$202233.92-85.8Link
DELEAGE JEANDirector, 10% Owner2004-02-19Sell111,69644,573$202233.92-85.8Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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