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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
SIEGALL CLAY BPresident and CEO
(Click for the stocks that their CEOs have bought)
2017-05-05Sell14,462636,435$61.74892.887.99636,435 (Direct)
SIEGALL CLAY BPresident and CEO2017-04-05Sell14,465636,435$62.99911.155.84636,435 (Direct)
HIMES VAUGHN BChief Technical Officer2017-03-31Sell10,000151,283$62.75627.56.25151,283 (Direct)
SIEGALL CLAY BPresident and CEO2017-03-06Sell14,465636,435$68.04984.2-2.01636,435 (Direct)
SIEGALL CLAY BPresident and CEO2017-02-06Sell14,465636,435$61.54890.188.34636,435 (Direct)
SIEGALL CLAY BPresident and CEO2017-01-06Sell14,465638,835$57.89837.3815.17638,835 (Direct)
Cline Darren SEVP, Commercial2016-12-13Sell10,00058,504$63.38633.85.1958,504 (Direct)
DOBMEIER ERICCOO2016-12-08Sell12,50087,767$65.928241.1487,767 (Direct)
HIMES VAUGHN BChief Technical Officer2016-12-07Sell30,000135,379$65.321959.62.07135,379 (Direct)
SIEGALL CLAY BPresident and CEO2016-12-06Sell14,465638,835$66.17957.150.76638,835 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2016-11-09Sell7,751109,837$66.75517.38-0.12109,837 (Direct)
BAKER FELIXDirector, 10% Owner2016-11-08Buy382,50040,992,596$59.3622705.212.31107,504 (Direct)
40,885,092 (See footnote(,,,))
SIEGALL CLAY BPresident and CEO2016-11-07Sell14,465638,835$58.43845.1914.1638,835 (Direct)
LIPPMAN MARC EDirector2016-11-07Sell1,000131,350$57.7557.7515.45131,350 (Direct)
BAKER FELIXDirector, 10% Owner2016-11-03Buy198,43345,482,921$56.4311197.5718.15107,504 (Direct)
4,835,170 (See footnote(,,,))
40,540,247 (See Footnote(,,,))
BAKER FELIXDirector, 10% Owner2016-11-03Buy1,030,62945,194,447$56.1357849.2118.78107,504 (Direct)
4,725,543 (See footnote(,,,))
40,361,400 (See Footnote(,,,))
DRACHMAN JONATHAN GCMO & EVP, R & D2016-11-01Sell3,418109,837$51.74176.8528.86109,837 (Direct)
SIEGALL CLAY BPresident and CEO2016-10-06Sell14,465638,835$54.41787.0422.53638,835 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2016-09-22Sell2,249113,255$56.75127.6317.48113,255 (Direct)
DOBMEIER ERICCOO2016-09-14Sell22,91887,767$54.041238.4923.3787,767 (Direct)
BAKER FELIXDirector, 10% Owner2016-09-13Buy447,31144,233,991$50.7122683.1431.47107,504 (Direct)
4,693,991 (See footnote(,,,))
39,432,496 (See Footnote(,,,))
SIEGALL CLAY BPresident and CEO2016-09-08Sell31,269638,835$50.081565.9533.13638,835 (Direct)
0 (by Trust)
BAKER FELIXDirector, 10% Owner2016-09-08Buy414,01643,696,884$48.4320050.7937.66107,504 (Direct)
4,559,012 (See footnote(,,,))
39,030,368 (See Footnote(,,,))
SIEGALL CLAY BPresident and CEO2016-09-06Sell11,653644,983$45.4529.0546.85617,038 (Direct)
27,945 (by Trust)
Cline Darren SEVP, Commercial2016-09-06Sell5,39751,576$46.01248.3244.951,576 (Direct)
DOBMEIER ERICCOO2016-08-23Sell12,58958,767$48604.2738.958,767 (Direct)
Cline Darren SEVP, Commercial2016-08-22Sell1,77440,973$46.5982.6543.140,973 (Direct)
DOBMEIER ERICCOO2016-08-22Sell5,41167,525$46.59252.143.167,525 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2016-08-22Sell3,99184,255$46.59185.9443.184,255 (Direct)
HIMES VAUGHN BEVP, Proc Svcs & Tech Ops2016-08-22Sell3,991108,779$46.59185.9443.1108,779 (Direct)
SIEGALL CLAY BPresident and CEO2016-08-22Sell23,381560,679$46.591089.3243.1532,734 (Direct)
27,945 (by Trust)
SIMPSON TODD ECFO2016-08-22Sell3,991191,445$46.59185.9443.1191,445 (Direct)
SIEGALL CLAY BPresident and CEO2016-08-08Sell11,660584,060$47.19550.2441.28556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-07-27Sell4,042584,060$45.2182.747.5556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-07-06Sell7,618584,060$40.56308.9964.37556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-06-06Sell22,083584,060$43.59962.652.95556,115 (Direct)
27,945 (by Trust)
Cline Darren SEVP, Commercial2016-06-02Sell3,36642,747$42.07141.6158.4742,747 (Direct)
SIEGALL CLAY BPresident and CEO2016-05-27Sell48,660584,060$40.411966.3564.98556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-05-24Sell8,400584,060$40.09336.7666.3556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-05-17Sell7,618584,060$35.16267.8589.62556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-04-25Sell800584,060$403266.68556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-04-05Sell7,618584,060$36.12275.1684.58556,115 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2016-03-22Sell15,236584,060$35.52541.1887.7556,115 (Direct)
27,945 (by Trust)
BAKER FELIXDirector, 10% Owner2016-03-17Buy124,06547,873,417$31.853951.47109.32107,504 (Direct)
4,486,246 (See footnotes(F4,F5,F8,F9))
38,783,387 (See footnotes(F5,F6,F8,F9))
4,496,280 (See Footnotes(F4,F5,F8,F9))
BAKER FELIXDirector, 10% Owner2016-03-16Buy1,349,23747,668,558$32.143310.51107.69107,504 (Direct)
4,484,096 (See footnotes(F4,F5,F14,F15))
38,671,506 (See footnotes(F5,F6,F14,F15))
4,405,452 (See Footnotes(F4,F5,F14,F15))
BAKER FELIXDirector, 10% Owner2016-03-11Buy694,66646,212,264$32.4622548.86105.39107,504 (Direct)
4,351,589 (See footnotes(F4,F5,F14,F15))
37,454,776 (See footnotes(F5,F6,F14,F15))
4,298,395 (See Footnotes(F4,F5,F14,F15))
BAKER FELIXDirector, 10% Owner2016-03-08Buy502,523127,365,973$22.6611387.17194.22107,504 (Direct)
4,255,959 (See footnotes(F4,F17))
36,682,540 (See footnotes(F5,F17))
4,249,772 (See Footnotes(F4,F17))
4,265,959 (See footnotes(F9,F12,F13,F17))
36,692,540 (See footnotes(F10,F12,F14,F17))
4,281,431 (See footnotes(F13,F17))
36,830,268 (See footnotes(F14,F17))
BAKER FELIXDirector, 10% Owner2016-03-02Buy675,92244,876,220$31.7721474.04109.85107,504 (Direct)
4,221,368 (See footnotes(F4,F9))
36,367,808 (See footnotes(F5,F9))
4,179,540 (See Footnotes(F4,F9))
BAKER FELIXDirector, 10% Owner2016-02-26Buy314,50844,148,952$29.559293.71125.62107,504 (Direct)
4,154,719 (See footnotes(F4,F9))
35,758,535 (See footnotes(F5,F9))
4,128,194 (See Footnotes(F4,F9))
BAKER FELIXDirector, 10% Owner2016-02-22Buy1,001,47143,804,485$29.6329673.59125.01107,504 (Direct)
4,122,878 (See footnotes(F4,F7))
35,475,868 (See footnotes(F5,F7))
4,098,235 (See Footnotes(F4,F7))
BAKER FELIXDirector, 10% Owner2016-02-17Buy1,269,14776,210,189$30.4338620.14119.09107,504 (Direct)
3,916,805 (See footnotes(F4,F11))
33,588,605 (See footnotes(F5,F11))
4,023,889 (See Footnotes(F4,F11))
34,573,386 (See Footnotes(F5,F11))
Orwin John ADirector2016-02-12Buy2,00010,700$28.3356.66135.3310,700 (Direct)
HIMES VAUGHN BEVP, Proc Svcs & Tech Ops2015-12-15Sell40,50076,212$39.941617.5766.9376,212 (Direct)
SIEGALL CLAY BPresident and CEO2015-12-03Sell3,720584,060$39.99148.7666.72556,115 (Direct)
27,945 (by Trust)
BAKER FELIXDirector, 10% Owner2015-11-20Buy329,35837,435,632$43.9414471.9951.73107,504 (Direct)
3,899,276 (See footnote)
33,428,852 (See Footnote)
SIEGALL CLAY BPresident and CEO2015-11-17Sell87,473584,060$45.43971.2746.85556,115 (Direct)
27,945 (by Trust)
Cline Darren SSVP, Commercial2015-11-11Sell5,76937,713$45.68263.5345.9537,713 (Direct)
BAKER FELIXDirector, 10% Owner2015-11-10Buy934,6244,006,780$42.9540142.155.23107,504 (Direct)
3,899,276 (See footnote)
DOBMEIER ERICCOO2015-11-06Sell17,45280,888$42.5741.7156.8780,888 (Direct)
GRYSKA DAVID WDirector2015-11-05Sell10,00023,950$43.57435.753.0223,950 (Direct)
SIEGALL CLAY BPresident and CEO2015-11-04Sell3,718671,533$43.14160.3954.54643,588 (Direct)
27,945 (by Trust)
SIEGALL CLAY BPresident and CEO2015-10-05Sell3,718639,268$41.3153.5561.43611,323 (Direct)
27,945 (by Trust)
BAKER FELIXDirector, 10% Owner2015-09-15Buy5,159,4844,006,780$42.56219587.6456.65107,504 (Direct)
3,899,276 (See footnote)
SIEGALL CLAY BPresident and CEO2015-09-03Sell3,718639,268$40.12149.1766.18611,323 (Direct)
27,945 (by Trust)
DOBMEIER ERICCOO2015-08-20Sell8,54898,340$42.02359.1958.6698,340 (Direct)
Cline Darren SSVP, Commercial2015-08-20Sell2,23143,482$42.0293.7558.6643,482 (Direct)
SIEGALL CLAY BPresident and CEO2015-08-20Sell31,754639,268$42.021334.358.66611,323 (Direct)
27,945 (by Trust)
DOBMEIER ERICCOO2015-08-20Sell8,54898,340$42.02359.1958.6698,340 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2015-08-20Sell4,46282,724$42.02187.4958.6682,724 (Direct)
Cline Darren SSVP, Commercial2015-08-20Sell2,23143,482$42.0293.7558.6643,482 (Direct)
SIMPSON TODD ECFO2015-08-20Sell5,825179,874$42.02244.7758.66179,874 (Direct)
HIMES VAUGHN BEVP, Proc Svcs & Tech Ops2015-08-20Sell5,99776,212$42.02251.9958.6676,212 (Direct)
SIEGALL CLAY BPresident and CEO2015-08-05Sell3,718657,022$46.91174.4142.12557,022 (Direct)
100,000 (by Trust)
SIEGALL CLAY BPresident and CEO2015-07-06Sell3,718657,022$46.94174.5242.03557,022 (Direct)
100,000 (by Trust)
SIEGALL CLAY BPresident and CEO2015-06-03Sell3,718657,022$45.72169.9945.82557,022 (Direct)
100,000 (by Trust)
BAKER FELIXDirector, 10% Owner2015-05-21Buy950,8864,006,780$42.4940403.1556.91107,504 (Direct)
3,899,276 (See footnote)
SIEGALL CLAY BPresident and CEO2015-05-08Sell52,052657,022$40.652115.9164.01557,022 (Direct)
100,000 (by Trust)
DOBMEIER ERICCOO2015-05-08Sell17,07482,777$40.38689.4565.1182,777 (Direct)
BAKER FELIXDirector, 10% Owner2015-05-07Buy1,032,6643,993,080$35.5636721.5387.49107,504 (Direct)
3,885,576 (See footnote)
Cline Darren SSVP, Commercial2015-03-13Sell7,50033,135$38.65289.8872.533,135 (Direct)
HIMES VAUGHN BEVP, Proc Svcs & Tech Ops2015-03-12Sell20,00067,209$36.6573381.9167,209 (Direct)
BAKER FELIXDirector, 10% Owner2015-03-10Buy285,0363,993,080$34.669879.3592.35107,504 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2015-03-04Buy448,8413,993,080$34.8415637.6291.36107,504 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2015-02-25Buy281,1153,993,080$33.929535.4296.55107,504 (Direct)
3,885,576 (See footnote)
SIEGALL CLAY BPresident and CEO2015-01-06Sell16,804659,710$31.8534.37109.65559,710 (Direct)
100,000 (by Trust)
BAKER FELIXDirector, 10% Owner2014-12-16Buy2,883,3783,993,080$31.8691864.42109.26107,504 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2014-12-10Buy1,247,8963,993,080$33.8242203.8497.13107,504 (Direct)
3,885,576 (See footnote)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2014-11-12Sell10,00067,209$37.52375.277.6967,209 (Direct)
BAKER FELIXDirector, 10% Owner2014-11-10Buy1,653,925493,205$34.5657159.6592.9176,997 (Direct)
416,208 (See footnote)
SIEGALL CLAY BPresident and CEO2014-09-04Sell5,600659,710$42.54238.2256.72559,710 (Direct)
100,000 (by Trust)
DOBMEIER ERICCOO2014-08-25Sell4,81891,432$43.55209.8253.0991,432 (Direct)
SIMPSON TODD ECFO2014-08-24Sell3,696168,699$43.55160.9653.09168,699 (Direct)
SIEGALL CLAY BPresident and CEO2014-08-24Sell25,507659,710$43.551110.8353.09559,710 (Direct)
100,000 (by Trust)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2014-08-24Sell3,31067,209$43.55144.1553.0967,209 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2014-08-24Sell2,77266,481$43.55120.7253.0966,481 (Direct)
BOERNER CHRISTOPHER S.Executive Vice President, Comm2014-08-24Sell1,24872,358$43.5554.3553.0972,358 (Direct)
SIEGALL CLAY BPresident and CEO2014-08-12Sell11,200625,217$40.38452.2665.11525,217 (Direct)
100,000 (by Trust)
BAKER FELIXDirector, 10% Owner2014-06-13Buy216,5953,962,573$39.928646.4767.0176,997 (Direct)
3,885,576 (See footnote)
SIEGALL CLAY BPresident and CEO2014-06-10Sell11,200625,217$40.14449.5766.09525,217 (Direct)
100,000 (by Trust)
BAKER FELIXDirector, 10% Owner2014-06-09Buy546,2523,962,573$38.1620844.9874.7176,997 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2014-06-04Buy281,9633,962,573$34.869829.2391.2576,997 (Direct)
3,885,576 (See footnote)
BAKER FELIXDirector, 10% Owner2014-05-16Buy189,611467,941$34.076460.0595.6976,997 (Direct)
390,944 (See footnote)
BAKER FELIXDirector, 10% Owner2014-05-09Buy488,3823,949,073$33.9616585.4596.3276,997 (Direct)
3,872,076 (See footnote)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2014-05-09Sell10,00055,519$3535090.4955,519 (Direct)
SIEGALL CLAY BPresident and CEO2014-04-03Sell5,600955,696$43.34242.753.83955,696 (Direct)
SIEGALL CLAY BPresident and CEO2014-03-05Sell9,318955,696$52.89492.8326.05955,696 (Direct)
BOERNER CHRISTOPHER S.SVP, Commercial2014-02-21Sell1,45246,075$54.9879.8321.2646,075 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2014-02-20Sell1,24148,670$53.2566.0825.248,670 (Direct)
HIMES VAUGHN BEVP, Tech, Ops. & Proc. Sci.2014-02-19Sell5,08844,219$52.01264.6328.1944,219 (Direct)
SIEGALL CLAY BPresident and CEO2014-02-18Sell100,000955,696$51.97519728.29955,696 (Direct)
DOBMEIER ERICCOO2014-01-21Sell56,01077,833$47.92268439.1377,833 (Direct)
DRACHMAN JONATHAN GCMO & EVP, R & D2014-01-16Sell1,20149,911$45.7554.9545.7349,911 (Direct)
SIEGALL CLAY BPresident and CEO2014-01-02Sell1,8581,043,554$39.2772.9669.771,043,554 (Direct)
BAKER FELIXDirector, 10% Owner2013-12-16Buy407,0783,949,073$39.6616144.7168.176,997 (Direct)
3,872,076 (See footnote)
BAKER FELIXDirector, 10% Owner2013-12-05Buy1,005,9013,949,073$43.1943444.8654.3676,997 (Direct)
3,872,076 (See footnote)
SIEGALL CLAY BPresident and CEO2013-12-02Sell2,0001,024,558$41.2582.561.621,024,558 (Direct)
SIEGALL CLAY BPresident and CEO2013-11-01Sell2,0001,024,558$38.6377.2672.591,024,558 (Direct)
SIEGALL CLAY BPresident and CEO2013-10-01Sell2,0001,024,558$43.8787.7451.971,024,558 (Direct)
DOBMEIER ERICCOO2013-09-10Sell42,000133,843$46.41948.843.69133,843 (Direct)
DOBMEIER ERICCOO2013-09-05Sell75,000135,843$42.64319856.36135,843 (Direct)
SIEGALL CLAY BPresident and CEO2013-09-03Sell102,000977,211$43.94477.851.87977,211 (Direct)
GRYSKA DAVID WDirector2013-09-03Sell10,00022,000$42.48424.856.9422,000 (Direct)
SIMPSON TODD ECFO2013-08-27Sell37,763155,395$41.451565.2860.84155,395 (Direct)
SIEGALL CLAY BPresident and CEO2013-08-19Sell7,6531,124,558$40.91313.0862.971,124,558 (Direct)
SIMPSON TODD ECFO2013-08-19Sell3,328125,029$40.91136.1562.97125,029 (Direct)
DOBMEIER ERICCOO2013-08-19Sell3,328127,620$40.91136.1562.97127,620 (Direct)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2013-08-19Sell1,73646,307$40.9171.0262.9746,307 (Direct)
BOERNER CHRISTOPHER S.SVP, Commercial2013-08-19Sell22647,527$40.919.2562.9747,527 (Direct)
SIEGALL CLAY BPresident and CEO2013-08-01Sell2,0001,077,211$40.0380.0666.551,077,211 (Direct)
SIMPSON TODD ECFO2013-07-12Sell92,527113,957$37.453465.1478.02113,957 (Direct)
SIEGALL CLAY BPresident and CEO2013-07-01Sell2,0001,077,211$32.5965.18104.571,077,211 (Direct)
AKKARAJU SRINIVASDirector2013-06-14Sell5,00013,905$32.75163.75103.5713,905 (Direct)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2013-06-13Sell10,00033,643$32.11321.1107.6333,643 (Direct)
SIEGALL CLAY BPresident and CEO2013-06-03Sell2,0001,077,211$33.8867.7696.781,077,211 (Direct)
AKKARAJU SRINIVASDirector2013-05-10Sell17,50010,405$37.17650.4879.3710,405 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-09Buy488,3823,949,073$33.9616585.4596.3276,997 (Direct)
3,872,076 (See footnote)
SIEGALL CLAY BPresident and CEO2013-05-01Sell2,0001,077,211$36.5873.1682.261,077,211 (Direct)
SIEGALL CLAY BPresident and CEO2013-04-01Sell2,0001,077,211$35.5371.0687.641,077,211 (Direct)
BOERNER CHRISTOPHER S.SVP, Commercial2013-03-15Sell8,50033,753$33.61285.6998.3633,753 (Direct)
DOBMEIER ERICCOO2013-03-11Sell60,000112,948$31.161869.6113.96112,948 (Direct)
SIMPSON TODD ECFO2013-03-07Sell49,718113,957$30.751528.83116.81113,957 (Direct)
DOBMEIER ERICCOO2013-03-06Sell100,000122,948$29.682968124.63122,948 (Direct)
SIEGALL CLAY BPresident and CEO2013-03-05Sell95,7501,077,211$28.712748.98132.221,077,211 (Direct)
GRYSKA DAVID WDirector2013-02-25Sell10,00018,500$27.17271.7145.3818,500 (Direct)
SIEGALL CLAY BPresident and CEO2013-02-01Sell2,0001,170,961$29.6159.22125.161,170,961 (Direct)
Reynolds Thomas CChief Medical Officer2013-01-28Sell7,29057,601$30.09219.36121.5757,601 (Direct)
Reynolds Thomas CChief Medical Officer2013-01-15Sell125,07957,601$283502.21138.1157,601 (Direct)
SIEGALL CLAY BPresident and CEO2013-01-04Sell8,2491,170,961$24.13199.05176.31,170,961 (Direct)
DOBMEIER ERICCOO2013-01-04Sell50,983122,846$24.951272.03167.21122,846 (Direct)
DOBMEIER ERICCOO2012-12-17Sell50,000113,829$23.71185181.31113,829 (Direct)
Reynolds Thomas CChief Medical Officer2012-12-10Sell66,58857,601$25.771715.97158.7157,601 (Direct)
Reynolds Thomas CChief Medical Officer2012-12-05Sell40,00057,601$25.591023.6160.5357,601 (Direct)
SIEGALL CLAY BPresident and CEO2012-12-03Sell8,2501,170,961$25.19207.82164.671,170,961 (Direct)
Reynolds Thomas CChief Medical Officer2012-12-03Sell40,00057,601$25.411016.4162.3857,601 (Direct)
Reynolds Thomas CChief Medical Officer2012-11-26Sell30,00057,601$25.34760.2163.157,601 (Direct)
Reynolds Thomas CChief Medical Officer2012-11-20Sell20,00057,601$24.95499167.2157,601 (Direct)
DOBMEIER ERICCOO2012-11-13Sell27,327101,411$23.59644.64182.62101,411 (Direct)
SIEGALL CLAY BPresident and CEO2012-11-01Sell8,2501,170,961$25.51210.46161.351,170,961 (Direct)
DOBMEIER ERICCOO2012-10-15Sell25,00069,352$25.01625.25166.5769,352 (Direct)
SIEGALL CLAY BPresident and CEO2012-10-01Sell8,2501,170,961$26.59219.37150.731,170,961 (Direct)
HIMES VAUGHN BEVP, Tech. Ops. & Proc. Sci.2012-09-10Sell10,00033,643$28.79287.9131.5733,643 (Direct)
SIMPSON TODD ECFO2012-09-06Sell95,00070,762$28.52707.5133.9370,762 (Direct)
Reynolds Thomas CChief Medical Officer2012-09-06Sell48,54057,601$29.751444.07124.157,601 (Direct)
SIEGALL CLAY BPresident and CEO2012-09-04Sell8,2501,170,961$26.54218.96151.211,170,961 (Direct)
SIMPSON TODD ECFO2012-08-27Sell45,00070,762$26.971213.65147.270,762 (Direct)
SIMPSON TODD ECFO2012-08-16Sell40,00050,762$25.971038.8156.7250,762 (Direct)
DOBMEIER ERICCOO2012-08-13Sell25,00043,352$24.01600.25177.6843,352 (Direct)
SIEGALL CLAY BPresident and CEO2012-08-02Sell8,2501,096,711$26214.5156.421,096,711 (Direct)
SIEGALL CLAY BPresident & CEO2012-07-02Sell8,2501,096,711$25.36209.22162.891,096,711 (Direct)
DOBMEIER ERICCOO2012-06-18Sell25,00068,073$25.36634162.8968,073 (Direct)
SIMPSON TODD ECFO2012-06-14Sell95,00050,762$24.52327.5172.1250,762 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-06-12Sell10,00017,643$24240177.7917,643 (Direct)
SIMPSON TODD ECFO2012-06-08Sell35,00050,762$22.97803.95190.2550,762 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-06-07Sell13,56617,643$22.5305.24196.3117,643 (Direct)
GRYSKA DAVID WDirector2012-06-05Sell8,00011,500$19.75158237.5711,500 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-05-18Sell65,00017,643$21.541400.1209.5217,643 (Direct)
Reynolds Thomas CChief Medical Officer2012-05-15Sell94931,073$19.7518.74237.5731,073 (Direct)
Reynolds Thomas CChief Medical Officer2012-04-25Sell40,00031,073$19.75790237.5731,073 (Direct)
DOBMEIER ERICCOO2012-04-25Sell25,00068,073$19.95498.75234.1968,073 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-04-20Sell38,28117,643$19.51746.86241.7217,643 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-04-17Sell44,21917,643$18.88834.85253.1317,643 (Direct)
Reynolds Thomas CChief Medical Officer2012-03-22Sell40,00031,073$19.78791.2237.0631,073 (Direct)
Reynolds Thomas CChief Medical Officer2012-03-19Sell40,00031,073$19.75790237.5731,073 (Direct)
ROSENBERG MORRISEVP, Process Sciences2012-03-13Sell69,62617,643$18.591294.35258.6317,643 (Direct)
DOBMEIER ERICCOO2012-02-28Sell46,00072,073$18.52851.92259.9972,073 (Direct)
DOBMEIER ERICCOO2012-02-28Sell4,00068,073$18.5374.12259.7968,073 (Direct)
Reynolds Thomas CChief Medical Officer2012-01-27Sell40,00030,169$19.75790237.5730,169 (Direct)
SIEGALL CLAY BPresident and CEO2012-01-03Sell15,0001,130,055$16.73250.95298.511,045,055 (Direct)
85,000 (by Trust)
GRYSKA DAVID WDirector2011-12-09Sell10,00015,000$18.09180.9268.5515,000 (Direct)
SIEGALL CLAY BPresident and CEO2011-12-01Sell15,0001,130,055$15.97239.55317.471,045,055 (Direct)
85,000 (by Trust)
SIEGALL CLAY BPresident and CEO2011-11-01Sell15,0001,130,055$21.89328.35204.571,045,055 (Direct)
85,000 (by Trust)
DOBMEIER ERICCOO2011-10-27Sell20,91859,327$21.95459.15203.7459,327 (Direct)
DOBMEIER ERICCOO2011-10-20Sell20,46159,327$20.58421.09223.9659,327 (Direct)
SIMPSON TODD ECFO2011-10-07Sell24,35049,242$21.97534.97203.4649,242 (Direct)
SIEGALL CLAY BPresident and CEO2011-10-04Sell15,0001,130,055$20.15302.25230.871,045,055 (Direct)
85,000 (by Trust)
SIEGALL CLAY BPresident and CEO2011-09-21Sell30,0001,130,055$20.12603.6231.361,045,055 (Direct)
85,000 (by Trust)
14159 capital (GP), LLCDirector, 10% Owner2011-09-06Buy1,773323,148$17.0830.28290.34
323,148 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-09-06Buy129,18714,776,080$17.082206.51290.34
14,776,080 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-08-25Buy1,165,43514,646,893$15.3817924.39333.49
14,646,893 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-08-25Buy17,926321,375$15.38275.7333.49
321,375 (Through Partnership)
Reynolds Thomas CChief Medical Officer2011-08-01Sell1,5391,488$17.3726.73283.821,488 (Direct)
SIEGALL CLAY BPresident and CEO2011-07-01Sell15,0001,035,667$20.66309.9222.7950,667 (Direct)
85,000 (by Trust)
BERGER FRANKLIN MDirector2011-06-22Buy7,000163,720$20.04140.28232.68163,720 (Direct)
SIEGALL CLAY BPresident and CEO2011-06-20Sell9,0001,035,667$20.01180.09233.18950,667 (Direct)
85,000 (by Trust)
DOBMEIER ERICCOO2011-06-20Sell13,3858,817$20267.7233.358,817 (Direct)
SIEGALL CLAY BPresident and CEO2011-06-09Sell1,0001,035,667$2020233.35950,667 (Direct)
85,000 (by Trust)
DOBMEIER ERICChief Business Officer2011-06-09Sell3,60022,202$2072233.3522,202 (Direct)
SIMPSON TODD ECFO2011-06-07Sell10,7509,359$19.96214.57234.029,359 (Direct)
ROSENBERG MORRISEVP, Process Sciences2011-06-07Sell2,5030$19.6749.23238.94Link
ROSENBERG MORRISEVP, Process Sciences2011-05-27Sell17,4970$19.5341.19241.9Link
Reynolds Thomas CChief Medical Officer2011-05-19Sell19,9983,027$18.71374.16256.333,027 (Direct)
ROSENBERG MORRISEVP, Process Sciences2011-05-19Sell20,0000$18.8376254.63Link
SIMPSON TODD ECFO2011-05-18Sell21,2509,359$18.64396.1257.679,359 (Direct)
ROSENBERG MORRISEVP, Process Sciences2011-05-13Sell20,0000$17.8356274.55Link
Reynolds Thomas CChief Medical Officer2011-05-13Sell20,0003,027$17.8356274.553,027 (Direct)
DOBMEIER ERICChief Business Officer2011-05-13Sell42,71525,802$18768.87270.3925,802 (Direct)
SIEGALL CLAY BPresident and CEO2011-05-09Sell50,0001,030,667$17.35867.5284.27945,667 (Direct)
85,000 (by Trust)
SIMPSON TODD ECFO2011-05-09Sell20,0009,359$17.74354.8275.829,359 (Direct)
SIEGALL CLAY BPresident and CEO2011-05-02Sell50,0000$17.43871.5282.5Link
ROSENBERG MORRISEVP, Process Sciences2011-05-02Sell25,0000$17.15428.75288.75Link
SIMPSON TODD ECFO2011-04-29Sell15,0000$16.94254.1293.57Link
Reynolds Thomas CChief Medical Officer2011-04-29Sell11,9150$16.95201.96293.33Link
SIEGALL CLAY BPresident and CEO2011-04-14Sell50,0000$15.27763.5336.61Link
SIEGALL CLAY BPresident and CEO2011-04-07Sell50,0000$16.06803315.13Link
DOBMEIER ERICChief Business Officer2011-04-05Sell40,0000$16640316.69Link
SIEGALL CLAY BPresident and CEO2011-03-17Sell200,0000$14.092818373.17Link
14159 capital (GP), LLCDirector, 10% Owner2011-02-02Buy48,1970$15.5747.05330.13Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-02-02Buy1,751,80313,470,692$15.527152.95330.13
13,470,692 (Through Partnership)
ROSENBERG MORRISEVP, Process Sciences2010-12-15Sell25,0000$16.22405.5311.04Link
ROSENBERG MORRISEVP, Process Sciences2010-12-02Sell25,0000$15.81395.25321.7Link
ROSENBERG MORRISEVP, Process Sciences2010-11-04Sell25,0000$14.7367.5353.54Link
Reynolds Thomas CChief Medical Officer2010-10-11Sell25,0005,719$16.95423.75293.33Link
Reynolds Thomas CChief Medical Officer2010-09-27Sell25,0005,719$14.95373.75345.95Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-06-08Buy599,06911,718,889$11.947152.88458.38Link
14159 capital (GP), LLCDirector, 10% Owner2010-06-08Buy16,536255,252$11.94197.44458.38Link
LIPPMAN MARC EDirector2010-06-04Buy20,000103,575$12.49249.8433.79Link
14159 capital (GP), LLCDirector, 10% Owner2010-05-25Buy150238,716$11.951.79457.91Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-05-25Buy5,41611,119,820$11.9564.72457.91Link
BERGER FRANKLIN MDirector2010-05-13Buy5,000138,720$13.3766.85398.65Link
LIPPMAN MARC EDirector2010-05-10Buy11,07583,575$11.92132.01459.31Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-05-04Buy561,70911,114,404$12.797184.26421.27Link
14159 capital (GP), LLCDirector, 10% Owner2010-05-04Buy15,506238,566$12.79198.32421.27Link
Reynolds Thomas CChief Medical Officer2010-05-03Sell25,0004,508$12.95323.75414.83Link
14159 capital (GP), LLCDirector, 10% Owner2010-04-30Buy51,581223,060$11.06570.49502.8Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-04-30Buy1,868,68610,552,695$11.0620667.67502.8Link
BERGER FRANKLIN MDirector2010-03-30Buy11,500116,720$12.05138.58453.28Link
BERGER FRANKLIN MDirector2010-03-12Buy13,000105,220$11.9154.7460.25Link
AKKARAJU SRINIVASDirector2009-08-18Buy4,90510,405$11.4756.26481.26Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-11Buy273,4044,626,213$10.752939.09520.19Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-11Buy798481,890$10.758.58520.19Link
Reynolds Thomas CChief Medical Officer2009-07-30Sell25,0003,713$12.47311.75434.64Link
DOBMEIER ERICChief Business Officer2009-07-30Sell60,00012,206$12.36741.6439.4Link
ROSENBERG MORRISEVP, Development2009-07-28Sell25,0000$11.81295.25464.52Link
AKKARAJU SRINIVASDirector2009-06-25Buy5,5005,500$9.2150.66623.89
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-05-20Buy378,0534,352,809$9.723674.68585.91
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-20Buy746,5718,684,009$9.727256.67585.91
14159 capital (GP), LLCDirector, 10% Owner2009-05-20Buy14,576171,479$9.72141.68585.91
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-20Buy3,710481,092$9.7236.06585.91
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-20Buy35,253400,898$9.72342.66585.91
DOBMEIER ERICChief Business Officer2008-09-26Sell24,4279,000$11.53281.64478.23
AKKARAJU SRINIVASDirector2008-09-22Sell18,601600,559$12.79237.91421.27
Reynolds Thomas CChief Medical Officer2008-09-22Sell12,3092,626$12.52154.11432.51
AKKARAJU SRINIVASDirector2008-09-19Sell37,011603,588$12.74471.52423.31
AKKARAJU SRINIVASDirector2008-09-19Sell87,696603,588$12.741117.25423.31
AKKARAJU SRINIVASDirector2008-09-18Sell20,839617,871$12.71264.86424.55
AKKARAJU SRINIVASDirector2008-09-18Sell49,378617,871$12.71627.59424.55
DOBMEIER ERICChief Business Officer2008-09-16Sell30,00033,427$12.25367.5444.24
ROSENBERG MORRISSr. VP, Development2008-08-04Sell50,0000$11.3565490
AKKARAJU SRINIVASDirector2008-07-29Sell95,688625,913$10.851038.21514.47
AKKARAJU SRINIVASDirector2008-07-28Sell21,232685,702$10.36219.96543.53
H&Q Holdings, Inc.10% Owner2008-07-28Sell21,50025,052$10.36222.74543.53
SIEGALL CLAY BPresident and CEO, Director2008-07-25Sell100,000953,168$10.781078518.46
H&Q Holdings, Inc.10% Owner2008-07-25Sell150,00025,186$10.811621.5516.74
JP MORGAN PARTNERS BHCA LP10% Owner2008-07-25Sell150,00025,186$10.811621.5516.74
AKKARAJU SRINIVASDirector2008-07-25Sell148,136701,432$10.811601.35516.74
JP MORGAN PARTNERS BHCA LP10% Owner2008-07-25Sell21,50025,052$10.36222.74543.53
AKKARAJU SRINIVASDirector2008-05-16Sell42,059811,175$10.39436.99541.67
AKKARAJU SRINIVASDirector2008-05-15Sell98,758842,334$10.141001.41557.5
JP MORGAN PARTNERS BHCA LP10% Owner2008-05-15Sell100,00026,383$10.141014557.5
H&Q Holdings, Inc.10% Owner2008-05-14Sell122,89327,004$10.11241.22560.1
JP MORGAN PARTNERS BHCA LP10% Owner2008-05-14Sell122,89327,004$10.11241.22560.1
AKKARAJU SRINIVASDirector2008-05-14Sell121,365915,496$10.11225.79560.1
H&Q Holdings, Inc.10% Owner2008-05-13Sell51,53627,768$10.06518.45562.72
JP MORGAN PARTNERS BHCA LP10% Owner2008-05-13Sell51,53627,768$10.06518.45562.72
AKKARAJU SRINIVASDirector2008-05-13Sell50,8961,005,407$10.06512.01562.72
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-03-18Buy41,6663,974,756$7.9329.16743.92
14159 capital (GP), LLCDirector, 10% Owner2008-03-18Buy3,918156,903$7.930.95743.92
Baker Brothers Life Sciences CDirector, 10% Owner2008-03-18Buy123,4937,937,438$7.9975.59743.92
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-03-17Buy189477,241$7.81.47754.74
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-03-14Buy65,0043,933,090$8.04522.63729.23
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-03-14Buy361477,052$8.072.91726.15
Baker / Tisch Capital (GP), LLDirector, 10% Owner2008-03-14Buy819365,645$8.046.58729.23
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-03-14Buy361477,052$8.072.91726.15
Baker Brothers Life Sciences CDirector, 10% Owner2008-03-14Buy173,4077,813,945$8.041394.19729.23
14159 capital (GP), LLCDirector, 10% Owner2008-03-14Buy5,503152,985$8.0444.24729.23
Baker / Tisch Capital (GP), LLDirector, 10% Owner2008-02-11Buy1,158364,826$9.0310.46638.32
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-02-11Buy177476,588$9.031.6638.32
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-02-11Buy34,6533,868,086$9.01312.22639.96
Baker Brothers Life Sciences CDirector, 10% Owner2008-02-11Buy153,5387,640,538$9.011383.38639.96
14159 capital (GP), LLCDirector, 10% Owner2008-02-11Buy4,883147,482$9.0144639.96
Baker Bros. Capital (GP), LLCDirector, 10% Owner2008-01-23Buy5,006476,173$945.05640.78
Baker / Tisch Capital (GP), LLDirector, 10% Owner2008-01-23Buy43,170363,668$8.99388.1641.6
Baker Brothers Life Sciences CDirector, 10% Owner2008-01-23Buy2,094,2787,487,000$8.9918827.56641.6
14159 capital (GP), LLCDirector, 10% Owner2008-01-23Buy67,001142,599$8.99602.34641.6
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-01-22Buy578,9163,833,433$8.995204.45641.6
BERGER FRANKLIN MDirector2008-01-22Buy52872,220$9.124.82631.03
JP MORGAN PARTNERS BHCA LP10% Owner2007-12-10Sell21,22428,088$12.63268.06427.87
AKKARAJU SRINIVASDirector2007-12-10Sell20,9601,043,112$12.63264.72427.87
SIMPSON TODD ECFO2007-09-26Sell32,2500$11.91384.1459.78
ROSENBERG MORRISSr. VP, Development2007-09-26Sell15,0000$11.93178.95458.84
DOBMEIER ERICChief Business Officer2007-09-20Sell1,9003,798$11.922.61460.25
DOBMEIER ERICChief Business Officer2007-09-20Sell19,1003,798$11.8225.38465
DOBMEIER ERICChief Business Officer2007-09-20Sell16,5003,798$11.65192.23472.27
DOBMEIER ERICChief Business Officer2007-09-20Sell18,1003,798$11.61210.14474.25
DOBMEIER ERICChief Business Officer2007-09-19Sell44,4003,798$11.54512.38477.73
LIPPMAN MARC EDirector2007-09-17Buy2,00010,000$10.6221.24527.78
SIEGALL CLAY BPresident and CEO2007-08-22Sell74,0001,053,168$11.09820.66501.17
SIEGALL CLAY BPresident and CEO2007-08-21Sell65,7001,127,168$10.99722.04506.64
SIEGALL CLAY BPresident and CEO2007-08-21Sell110,3001,079,168$11.141228.74498.47
TrailSmith Pamela AChief Scientific Officer2007-05-17Sell59,8916,940$10.23612.68551.71
ROSENBERG MORRISSr. VP, Development2007-05-17Sell25,0000$10.32258546.03
ROSENBERG MORRISSr. VP, Development2007-04-27Sell25,0000$9.54238.5598.85
Baker Bros. Capital (GP), LLCDirector2007-02-14Sell149,9304,957$8.761313.39661.07
Baker Biotech Capital (GP), LLDirector2007-02-14Sell999,7821,153,217$8.768758.09661.07
14159 capital (GP), LLCDirector2007-02-14Sell19,56175,598$8.76171.35661.07
Baker Brothers Life Sciences CDirector2007-02-14Sell1,599,7923,474,819$8.7614014.18661.07
Baker / Tisch Capital (GP), LLDirector2007-02-14Sell102,9353,998$8.76901.71661.07
14159 capital (GP), LLCDirector2007-02-14Sell19,56175,598$8.72170.57664.56
Baker Biotech Capital (GP), LLDirector2007-02-14Sell999,7821,153,217$8.728718.1664.56
Baker Bros. Capital (GP), LLCDirector2007-02-14Sell149,9304,957$8.721307.39664.56
Baker Brothers Life Sciences CDirector2007-02-14Sell1,599,7923,474,819$8.7213950.19664.56
AKKARAJU SRINIVASDirector2007-02-09Sell2,015,0000$8.5717268.55677.95
DOBMEIER ERICSr. VP, Corporate Development2007-02-09Sell50,0001,798$8.94447645.75
14159 capital (GP), LLCDirector, 10% Owner2006-08-14Buy85095,159$4.053.441546.17Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-14Buy37,0704,149,611$4.05150.131546.17Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-08-14Buy12,0801,535,999$4.0548.921546.17Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-11Buy110,2194,112,541$4.03444.181554.34Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-08-11Buy35,9171,523,919$4.03144.751554.34Link
14159 capital (GP), LLCDirector, 10% Owner2006-08-11Buy2,52994,309$4.0310.191554.34Link
14159 capital (GP), LLCDirector, 10% Owner2006-08-09Buy4,65291,239$4.0518.841546.17Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-09Buy202,7613,978,746$4.05821.181546.17Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-08-09Buy66,0731,480,319$4.05267.61546.17Link
14159 capital (GP), LLCDirector, 10% Owner2006-08-07Buy1,49286,587$4.036.011554.34Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-07Buy65,0203,775,985$4.03262.031554.34Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-08-02Buy23,5763,734,541$3.787.231701.89Link
14159 capital (GP), LLCDirector, 10% Owner2006-08-02Buy54185,636$3.721701.89Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-08-02Buy7,6831,400,741$3.728.431701.89Link
14159 capital (GP), LLCDirector, 10% Owner2006-06-29Buy8,43585,095$4.0333.991554.34Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-06-29Buy392,8333,710,965$4.031583.121554.34Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-06-29Buy129,9821,393,058$4.03523.831554.34Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-06-26Buy50,5351,263,076$4.02203.151558.46Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-06-26Buy152,9413,318,132$4.02614.821558.46Link
14159 capital (GP), LLCDirector, 10% Owner2006-06-26Buy3,29776,660$4.0213.251558.46Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-06-21Buy115,7053,165,191$4.02465.131558.46Link
14159 capital (GP), LLCDirector, 10% Owner2006-06-21Buy2,49473,363$4.0210.031558.46Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-06-21Buy38,2321,212,541$4.02153.691558.46Link
14159 capital (GP), LLCDirector, 10% Owner2006-06-13Buy33,07870,869$4132.311566.75Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-06-13Buy507,0211,174,309$42028.081566.75Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-06-13Buy1,534,4433,049,486$46137.771566.75Link
Baker Brothers Life Sciences CDirector, 10% Owner2006-05-24Buy832,1351,515,043$5.254368.711169.9Link
14159 capital (GP), LLCDirector, 10% Owner2006-05-24Buy18,23037,791$5.2595.711169.9Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2006-05-24Buy278,650667,288$5.251462.911169.9Link
SIEGALL CLAY BPresident and CEO2005-09-13Sell73,0001,086,500$5.97435.811016.75Link
SIEGALL CLAY BPresident and CEO2005-09-09Sell24,0001,159,500$5.99143.761013.02Link
SIEGALL CLAY BPresident and CEO2005-08-02Sell103,0001,183,500$5.96613.881018.62Link
CARROLL TIMCFO2005-05-05Sell86,50062,861$5432.51233.4Link
Baker / Tisch Capital (GP), LLDirector, 10% Owner2005-05-04Buy67826,933$4.793.251291.86Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-05-04Buy94849,807$4.794.541291.86Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-05-04Buy1,22245,090$4.795.851291.86Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-05-04Buy6,305234,861$4.7930.21291.86Link
Baker Biotech Capital II (GP),Director, 10% Owner2005-05-04Buy6,627353,150$4.7931.741291.86Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2005-05-04Buy7,241388,638$4.7934.681291.86Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2005-05-04Buy1,44876,887$4.796.941291.86Link
14159 capital (GP), LLCDirector, 10% Owner2005-05-04Buy53119,561$4.792.541291.86Link
14159 capital (GP), LLCDirector, 10% Owner2005-04-29Buy6,39319,030$425.571566.75Link
Baker / Tisch Capital (GP), LLDirector, 10% Owner2005-04-29Buy8,41026,255$433.641566.75Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2005-04-29Buy89,394381,397$4357.581566.75Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-04-29Buy14,73443,868$458.941566.75Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2005-04-29Buy17,76675,439$471.061566.75Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-04-29Buy11,54248,859$446.171566.75Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-04-29Buy76,759228,556$4307.041566.75Link
Baker Biotech Capital II (GP),Director, 10% Owner2005-04-29Buy81,750346,523$43271566.75Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2005-03-30Buy12,040292,003$4.9659.721244.15Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2005-03-30Buy10,816264,773$4.9653.651244.15Link
BAKER TISCH CAPITAL GP LLCDirector, 10% Owner2005-03-30Buy1,13417,845$4.965.621244.15Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2005-03-30Buy2,34457,673$4.9611.631244.15Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-03-30Buy1,50637,317$4.967.471244.15Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-03-30Buy9,617151,797$4.9647.71244.15Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-03-30Buy1,84329,134$4.969.141244.15Link
14159 Capital (GP, LLCDirector, 10% Owner2005-03-30Buy80012,637$4.963.971244.15Link
BAKER TISCH CAPITAL GP LLCDirector, 10% Owner2005-03-29Buy96816,711$4.884.721266.19Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2005-03-29Buy2,00155,329$4.889.761266.19Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-03-29Buy1,28535,811$4.886.271266.19Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2005-03-29Buy9,229253,957$4.8845.041266.19Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2005-03-29Buy10,273279,963$4.8850.131266.19Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-03-29Buy8,205142,180$4.8840.041266.19Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-03-29Buy1,57327,291$4.887.681266.19Link
14159 Capital (GP, LLCDirector, 10% Owner2005-03-29Buy68211,837$4.883.331266.19Link
BAKER TISCH CAPITAL GP LLCDirector, 10% Owner2005-03-23Buy15,74315,743$4.9978.561236.07Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2005-03-23Buy150,679244,728$4.99751.891236.07Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2005-03-23Buy167,773269,690$4.99837.191236.07Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2005-03-23Buy32,67053,328$4.99163.021236.07Link
Baker Biotech Capital II (Z) (Director, 10% Owner2005-03-23Buy20,98434,526$4.99104.711236.07Link
Baker Biotech Capital III (GP)Director, 10% Owner2005-03-23Buy63,376133,975$4.96314.341244.15Link
14159 Capital (GP, LLCDirector, 10% Owner2005-03-23Buy5,25111,155$4.9626.041244.15Link
Baker Biotech Capital III (Z) Director, 10% Owner2005-03-23Buy12,16625,718$4.9660.341244.15Link
POWELL MICHAELDirector2004-12-16Sell56,500685,892$7395.5852.43Link
POWELL MICHAELDirector2004-12-07Sell22,450742,392$7.03157.82848.36Link
POWELL MICHAELDirector2004-12-06Sell135,000764,842$7.06953.1844.33Link
POWELL MICHAELDirector2004-12-01Sell32,500899,842$6.94225.55860.66Link
POWELL MICHAELDirector2004-11-16Sell54,000932,342$6.9372.6866.23Link
POWELL MICHAELDirector2004-11-15Sell146,000986,342$6.77988.42884.79Link
POWELL MICHAELDirector2004-09-29Sell50,0001,131,354$6.67333.5899.55Link
POWELL MICHAELDirector2004-09-24Sell10,0001,181,354$6.9269.2863.44Link
POWELL MICHAELDirector2004-09-23Sell94,4881,191,354$6.83645.35876.13Link
POWELL MICHAELDirector2004-09-17Sell55,5001,285,842$6.71372.41893.59Link
POWELL MICHAELDirector2004-09-02Sell26,0001,341,342$6.61171.86908.62Link
POWELL MICHAELDirector2004-08-27Sell35,0001,367,342$6.81238.35879Link
POWELL MICHAELDirector2004-08-24Sell121,0001,402,342$6.81824.01879Link
POWELL MICHAELDirector2004-08-19Sell44,0001,523,342$6.75297887.7Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2004-08-12Buy32,72392,120$5.55181.611101.26Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2004-08-12Buy45,745188,823$5.49251.141114.39Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2004-08-12Buy17,65029,619$5.495.311134.63Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2004-08-06Buy21,88962,682$5.53121.051105.61Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2004-08-06Buy4,21311,969$5.5323.31105.61Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2004-08-06Buy20,73459,397$5.53114.661105.61Link
BAKER BIOTECH CAPITAL GP LLCDirector, 10% Owner2004-08-04Buy38,66338,663$5.72221.151065.56Link
BAKER BIOTECH CAPITAL II GP LLDirector, 10% Owner2004-08-04Buy40,79340,793$5.72233.341065.56Link
BAKER BROS CAPITAL GP LLCDirector, 10% Owner2004-08-04Buy7,7567,756$5.7244.361065.56Link
POWELL MICHAELDirector2004-06-29Sell28,5001,567,342$7.03200.36848.36Link
CARROLL TIMCFO2004-06-28Sell60,000152,361$7.04422.4847.02Link
POWELL MICHAELDirector2004-06-25Sell121,5001,595,842$7.08860.22841.67Link
POWELL MICHAELDirector2004-06-22Sell80,0001,717,342$7.12569.6836.38Link
CARROLL TIMCFO2004-05-10Sell8,600212,361$8.2270.69711.07Link
DOBMEIER ERICV. P., Corporate Affairs2004-05-05Sell15,000300$8.59128.85676.14Link
POWELL MICHAELDirector2004-03-09Sell65,0001,797,342$10.42677.3539.83Link
POWELL MICHAELDirector2003-12-30Sell7,0001,862,342$8.962.3649.1Link
POWELL MICHAELDirector2003-12-23Sell87,2501,869,342$7.22629.95823.41Link
POWELL MICHAELDirector2003-12-09Sell56,0001,956,592$7.02393.12849.72Link
CARROLL TIMCFO2003-12-05Sell80,000220,961$6.63530.4905.58Link
POWELL MICHAELDirector2003-12-04Sell11,7032,012,592$6.5676.77916.31Link
POWELL MICHAELDirector2003-12-02Sell153,0002,024,295$6.33968.49953.24Link
SIEGALL CLAY BPresident and CEO2003-12-02Sell50,0001,291,500$6.47323.5930.45Link
FELL H PERRYChairman2003-12-02Sell50,0001,294,000$6.47323.5930.45Link
SIEGALL CLAY BPresident and CEO2003-11-26Sell4,5001,341,500$6.4428.98935.25Link
FELL H PERRYChairman2003-11-26Sell4,5001,344,000$6.4428.98935.25Link
POWELL MICHAELDirector2003-11-26Sell108,5002,177,295$6.27680.3963.32Link
SIEGALL CLAY BPresident and CEO2003-11-24Sell56,5001,346,000$6.52368.38922.55Link
FELL H PERRYChairman2003-11-24Sell56,5001,348,500$6.52368.38922.55Link
HELLSTROM KARL ERIKDirector2003-11-19Sell66,500700,000$6.69444.89896.56Link
POWELL MICHAELDirector2003-11-18Sell414,4782,285,795$62486.871011.17Link
HELLSTROM KARL ERIKDirector2003-11-18Sell133,500766,500$6.48865.08928.86Link
SIEGALL CLAY BPresident and CEO2003-09-15Sell10,0001,402,500$5.9591030Link
FELL H PERRYChairman2003-09-15Sell10,0001,405,000$5.9591030Link
SIEGALL CLAY BPresident and CEO2003-09-11Sell47,5001,412,500$6.05287.381001.98Link
FELL H PERRYChairman2003-09-11Sell47,5001,415,000$6.05287.381001.98Link
SIEGALL CLAY BPresident and CEO2003-09-08Sell31,5001,460,000$6.18194.67978.8Link
FELL H PERRYChairman2003-09-08Sell31,5001,462,500$6.18194.67978.8Link
SENTER PETERVice President, Chemistry2003-08-21Sell19,60068,148$5.27103.291165.09Link
SING AMYSr. Director Medical Affairs2003-08-18Sell20,00052,107$5.09101.81209.82Link
LIPPMAN MARC EDirector2003-08-14Buy15,00052,500$4.8873.21266.19Link
SING AMYSr. Director Medical Affairs2003-08-04Sell5,00072,107$4.723.51318.51Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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