Lilly and Incyte Announce Top-Line Results from Phase 3 Study (BREEZE-AD4) of Oral Selective JAK Inhibitor Baricitinib in Combination with Topical Corticosteroids in Patients with Moderate to Severe Atopic Dermatitis Not Controlled with Cyclosporine

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Jan 27, 2020
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- Study met primary endpoint of at least 75% improvement of skin inflammation

- Safety profile was consistent with the known safety findings of baricitinib in atopic dermatitis (AD)

- Study was conducted outside of the U.S. and is the first and only report of a JAK inhibitor in patients who failed, were intolerant, or contraindicated to cyclosporine

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