First Manhattan Co Buys IAC/InterActiveCorp, Enanta Pharmaceuticals Inc, Regenxbio Inc, Sells Amgen Inc, Vipshop Holdings, Humana Inc

• New Purchases: IMCR, FCOB, GE, BKCC, IMUX, MRSN, NEXI, ADTN, AAP, AU, AJG, ASH, BMI, SAN, CRH, CPE, CX, DY, E, EXP, FFIV, FLS, FC, GENC, GVA, HMC, LRCX, LNN, MTZ, MSB, NAT, OCC, PTC, TPC, AVNT, RFIL, RSG, R, SCCO, STLD, STRL, SSYS, TROW, TEX, X, MNTX, WPP, HEES, IDT, HQH, MYD, MNP, VG, NECB, PRIM, SQM, ACM, ORN, AMTX, TAK, IRDM, MYRG, LAC, CULL, PRLB, ICLR, NVEE, VOYA, XLRN, SMLR, PLXP, AGTC, TWOU, ARES, SUM, HRI, ROKU, AQUA, SBT, GH, ESTC, PAE, ATCX, CVET, PD, ALTG, TXG, OCFT, REAX, MEG, OSH, U, PLTR, FSR, AI, UPST, BOAC, TSP, PATH, IMPL, REVH, CMLT, CHPT, CHPT, PTRA, CXM, BASE, BLFY, HOOD, USCB, MTTR, AMBP, IRNT, WRBY, AOR, BCI, DFAS, DFIV, DFUS, FXL, FXO, IEZ, IPO, IWO, IYR, KBWD, SHY, SPTS, SRLN, VIS, VLUE, VOOG, VTIP,
• Added Positions: IAC, AMZN, ENTA, UNH, GDDY, VMEO, LOW, KKR, FB, NEE, BABA, CMCSA, MAR, PYPL, RGNX, WH, IVV, AZO, RTX, PM, ABBV, COTY, FTV, EOLS, AMT, C, CCI, HURC, NKE, ORLY, UNP, DIS, TRS, GRBK, HHC, IQV, HLT, LOV, GTES, AMAL, JOAN, IVE, IVW, IWD, IWF, VGT, VOO, CB, ASML, AEM, IEP, ADI, AMAT, BBY, BHC, BA, HLX, CAT, CLX, COLM, CVGI, CPRT, DD, DUK, EOG, ETN, EME, ESGR, EXAS, FICO, FISV, F, GIS, GIL, GS, HIG, KIM, KGC, LAMR, LYG, LMT, MRO, MCK, NCR, NFLX, NOC, NWPX, NUE, VWTR, PH, PAYX, PEG, RRC, REGN, RIO, SBAC, CRM, SONY, SO, SKT, TEVA, TAC, WAT, WSO, SPB, MGYR, LEN.B, RDS.B, MCR, SPE, EOI, ETV, HBI, TAST, LULU, BEP, DGEAF, QIPT, BCML, MNSB, OCSL, NVGS, CCXI, TSLA, PHYS, APO, BCOV, CG, NRZ, TWTR, NEP, OEC, LNTH, LC, QSR, NVTA, UNIT, SHOP, TRU, TDOC, LITE, Z, DSKE, PDSB, TEAM, EDIT, NTLA, CRSP, FND, ESQ, APRN, CLXT, KALA, BHF, SE, SPOT, DOCU, PTON, OYST, MSGE, HYMC, GSAH.U, NNOX, SNOW, MSP, SCPS, POSH, HIMS, BMBL, CPNG, ACVA, COIN, ACES, BND, DGRO, EFA, EFV, EZU, GLD, IFRA, IJH, IJR, IJS, IWB, IWM, IXN, LQD, PAVE, QQQ, QUAL, RWO, SCHE, SCHF, SCZ, SPDW, TIP, VAW, VB, VBK, VBR, VCR, VCSH, VEA, VEU, VFH, VOE, VONE, VONV, VOOV, VOX, VTV, VUG, VWO, VXUS, XLB, XLE, XLF, XLI, XLK, XLP, XLRE, XLV, XLY,
• Reduced Positions: AMGN, VIPS, NSRGY, LYB, BAM, D, GILD, BKNG, IAA, LSXMK, AEE, DHR, MDLZ, RBGPF, BUD, SABR, GOOS, ACN, AON, BAX, COF, KO, JNJ, ORCL, ALSN, AXP, BMY, CNQ, CME, CL, DPZ, HON, HBAN, MTCH, IBM, NUAN, SCI, VZ, FWONA, ALLY, FWONK, BATRK, LSXMA, GDS, BAMR, T, ATVI, A, AKAM, ARLP, ALL, HES, UHAL, ACC, AEP, AFG, AIG, ANAT, AMSC, AMP, APH, ARCH, AZN, AXS, BCE, BOCH, BOH, BK, BDX, BHLB, LCTX, BIIB, BXP, BRKL, CBZ, VIAC, CVS, CDNS, CPT, CNI, KMX, CSL, CCL, LUMN, FIS, CVX, CHD, CTAS, CSCO, CTSH, SBS, ED, CWCO, COO, DEO, ECL, ENB, EPD, ERIC, EL, XOM, FMC, FLEX, FLR, FELE, GD, GPC, GSK, GGG, PEAK, HTBK, HPQ, IEX, IDXX, INTC, IP, IPG, ISBC, JCI, KLAC, KSU, K, LKQ, LVS, LEG, LEN, JEF, LBTYA, MTB, CLI, MMP, MAN, MFC, MLM, MKC, MRK, MET, MSEX, MS, MSI, VTRS, NVDA, NDAQ, NTIP, NWL, NSC, NTRS, OMC, OLP, GLT, PNM, PPG, PMBC, PRK, PKBK, PBCT, PFE, LIN, PG, PGR, PFS, QCOM, RPT, RAVN, O, RDS.A, POOL, SEIC, SFE, BFS, SEE, SPG, SON, LUV, SWX, STT, SPH, SBOW, NLOK, SNPS, TJX, TGT, TTE, TM, TRST, UGI, UCBI, URI, USM, VTR, VOD, WAB, WBA, WM, ANTM, EVRG, WNEB, WY, WTM, WMB, WSM, WEC, WEX, ZBRA, ZBH, EVV, POR, FRST, LBTYK, DAL, BX, MG, GPDNF, AVGO, CHTR, DDEJF, BAH, FRC, KMI, HII, MOS, MPC, XYL, ANGI, PSX, FRGI, NOW, FANG, ALEX, BURL, VEEV, ALDX, PAYC, CGC, AGFS, ACB, VBTX, AVNS, LBRDK, STOR, TLRY, TLRY, CC, LILA, LILAK, HPE, BATRA, BBU, CDEV, TWLO, VRS, ASIX, VST, LW, JNCE, KRP, FPH, SMHI, BKR, MFGP, APG, VYNE, NVT, UXIN, AQST, KLXE, DOW, PINS, BYND, CTVA, CARR, OTIS, BIPC, BEPC, SKLZ, ZIM, OGN, IEF, IEMG, ITOT, IUSV, JETS, MTUM, PFF, SCIF, SPSB, SPTM, SPY, VIG, VTWO, XLU,
• Sold Out: HUM, GRA, ASND, NWHM, ETSY, SITM, DT, WORK, CANG, EAF, CAAP, ICLK, DNLI, CVNA, AQMS, DFNS, QRVO, TRUE, ESI, PGEN, BPY, TMHC, QLYS, VAC, IUSG, SPYV, SPYG, SPEM, SMOG, SLYV, SGOL, SCHV, SCHA, PDBC, MOAT, KBWB, GLEO, IRBO, FTEC, FIW, DBO, KPLT, CMLTU, REVHU, MUDS, MUDS, LRMR, ST, VALE, DIN, EHC, WELL, GPK, BPYU, EIX, DIOD, DKS, CW, DXC, INTZ, CLF, CTXS, CRL, CERN, CVBF, BDSI, BOKF, AVA, ALXN, AEG, UBS, ASX, GNRC, MSGN, PEB, ARI, FTNT, VIACA, WST, WRI, UHS, HZNP, USPH, TTWO, SUI, SWKS, SBNY, RMD, RJF, NBIX, MPWR, MAS,

For the details of FIRST MANHATTAN CO's stock buys and sells, go to https://www.gurufocus.com/guru/first+manhattan+co/current-portfolio/portfolio

1. Berkshire Hathaway Inc (BRK.A) - 18,704 shares, 28.35% of the total portfolio. Shares reduced by 0.55%
2. Microsoft Corp (MSFT) - 5,125,099 shares, 5.32% of the total portfolio. Shares reduced by 0.34%
3. Apple Inc (AAPL) - 10,016,970 shares, 5.22% of the total portfolio. Shares added by 0.15%
4. Brookfield Asset Management Inc (BAM) - 17,008,181 shares, 3.35% of the total portfolio. Shares reduced by 2.54%
5. Alphabet Inc (GOOG) - 264,069 shares, 2.59% of the total portfolio. Shares added by 0.56%

First Manhattan Co initiated holding in Immunocore Holdings PLC. The purchase prices were between $27.98 and $40, with an estimated average price of $33.84. The stock is now traded at around $37.900000. The impact to a portfolio due to this purchase was 0.03%. The holding were 197,999 shares as of 2021-09-30.

First Manhattan Co initiated holding in 1st Colonial Bancorp Inc. The purchase prices were between $9.13 and $10, with an estimated average price of $9.58. The stock is now traded at around $9.700000. The impact to a portfolio due to this purchase was 0.02%. The holding were 452,591 shares as of 2021-09-30.

First Manhattan Co initiated holding in Mersana Therapeutics Inc. The purchase prices were between $8.56 and $14.47, with an estimated average price of $11.75. The stock is now traded at around $8.880000. The impact to a portfolio due to this purchase was 0.01%. The holding were 218,070 shares as of 2021-09-30.

First Manhattan Co initiated holding in Immunic Inc. The purchase prices were between $8.05 and $13.29, with an estimated average price of $9.9. The stock is now traded at around $9.250000. The impact to a portfolio due to this purchase was 0.01%. The holding were 250,000 shares as of 2021-09-30.

First Manhattan Co initiated holding in BlackRock Capital Investment Corp. The purchase prices were between $3.81 and $4.24, with an estimated average price of $4.01. The stock is now traded at around $4.320000. The impact to a portfolio due to this purchase was 0.01%. The holding were 440,411 shares as of 2021-09-30.

First Manhattan Co initiated holding in NexImmune Inc. The purchase prices were between $10.32 and $16.9, with an estimated average price of $13.45. The stock is now traded at around $10.840000. The impact to a portfolio due to this purchase was 0.01%. The holding were 147,159 shares as of 2021-09-30.

First Manhattan Co added to a holding in IAC/InterActiveCorp by 23.07%. The purchase prices were between $124.28 and $153.83, with an estimated average price of $134.57. The stock is now traded at around $137.170000. The impact to a portfolio due to this purchase was 0.33%. The holding were 3,691,090 shares as of 2021-09-30.

First Manhattan Co added to a holding in Enanta Pharmaceuticals Inc by 2820.89%. The purchase prices were between $41.02 and $58.65, with an estimated average price of $49.48. The stock is now traded at around $91.960000. The impact to a portfolio due to this purchase was 0.19%. The holding were 969,736 shares as of 2021-09-30.

First Manhattan Co added to a holding in Regenxbio Inc by 44.39%. The purchase prices were between $29.09 and $45.68, with an estimated average price of $36.02. The stock is now traded at around $31.840000. The impact to a portfolio due to this purchase was 0.03%. The holding were 568,268 shares as of 2021-09-30.

First Manhattan Co added to a holding in iShares Core S&P 500 ETF by 690.61%. The purchase prices were between $425.18 and $453.54, with an estimated average price of $441.59. The stock is now traded at around $471.150000. The impact to a portfolio due to this purchase was 0.03%. The holding were 16,334 shares as of 2021-09-30.

First Manhattan Co added to a holding in Wyndham Hotels & Resorts Inc by 295.17%. The purchase prices were between $66.49 and $79.04, with an estimated average price of $71.78. The stock is now traded at around $85.620000. The impact to a portfolio due to this purchase was 0.03%. The holding were 148,326 shares as of 2021-09-30.

First Manhattan Co added to a holding in Evolus Inc by 46.78%. The purchase prices were between $7.36 and $13.67, with an estimated average price of $10.37. The stock is now traded at around $7.010000. The impact to a portfolio due to this purchase was 0.02%. The holding were 2,029,907 shares as of 2021-09-30.

First Manhattan Co sold out a holding in Humana Inc. The sale prices were between $389.15 and $471.22, with an estimated average price of $424.73.

First Manhattan Co sold out a holding in W R Grace & Co. The sale prices were between $69.29 and $69.99, with an estimated average price of $69.57.

First Manhattan Co sold out a holding in Ascendis Pharma A/S. The sale prices were between $112.67 and $176.92, with an estimated average price of $137.27.

First Manhattan Co sold out a holding in . The sale prices were between $4.7 and $8.99, with an estimated average price of $7.8.

First Manhattan Co sold out a holding in Mudrick Capital Acquisition Corporation II. The sale prices were between $9.83 and $12.39, with an estimated average price of $10.52.

First Manhattan Co sold out a holding in . The sale prices were between $18.26 and $19.11, with an estimated average price of $18.8.