Prothena (PRTA) Faces Setbacks After Birtamimab Trial Fails

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May 23, 2025
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Key Highlights for Prothena Investors:

  • Prothena's workforce and expenses are set for reductions after a failed phase 3 trial.
  • Analysts offer a diverse range of price targets with significant potential upside.
  • The stock's GF Value reflects potential notable gains based on historical performance.

Prothena Corp PLC (PRTA, Financial) is undergoing substantial restructuring following the unsuccessful phase 3 trial of its drug, birtamimab, targeting AL amyloidosis. With the trial's failure to achieve primary or secondary endpoints, the company is halting development and focusing on cost-cutting measures. This announcement triggered a sharp decline in Prothena shares, which plunged approximately 23% in after-hours trading.

Analyst Price Targets and Recommendations

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Prothena Corp PLC (PRTA, Financial) presents an intriguing opportunity for investors, given the one-year price targets from 8 analysts. The average target price is set at $49.00, with a high of $110.00 and a low of $18.00. This forecast suggests a remarkable potential upside of 644.68% from the current trading price of $6.58. Detailed projections and insights are available on the Prothena Corp PLC (PRTA) Forecast page.

The consensus from 10 brokerage firms rates Prothena Corp PLC as an "Outperform," with an average recommendation score of 2.0 on a scale where 1 represents a Strong Buy and 5 indicates a Sell.

Assessing Prothena's GF Value

According to GuruFocus estimates, the projected GF Value for Prothena Corp PLC in one year is $28.79. This valuation implies an impressively significant upside of 337.54% from the current stock price of $6.58. GuruFocus' GF Value metric considers historical trading multiples along with anticipated business growth and future performance estimates. For a comprehensive overview, visit the Prothena Corp PLC (PRTA, Financial) Summary page.

In conclusion, while Prothena faces challenges following the phase 3 trial setback, the substantial potential upside reflected in analysts' targets and the GF Value metric presents a compelling case for investors willing to consider the risks involved. As always, staying informed with the latest data and expert forecasts remains paramount.

Disclosures

I/We may personally own shares in some of the companies mentioned above. However, those positions are not material to either the company or to my/our portfolios.