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Karyopharm Therapeutics (Karyopharm Therapeutics) Cyclically Adjusted PB Ratio : 0.37 (As of Apr. 29, 2024)


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What is Karyopharm Therapeutics Cyclically Adjusted PB Ratio?

As of today (2024-04-29), Karyopharm Therapeutics's current share price is $1.06. Karyopharm Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2023 was $2.88. Karyopharm Therapeutics's Cyclically Adjusted PB Ratio for today is 0.37.

The historical rank and industry rank for Karyopharm Therapeutics's Cyclically Adjusted PB Ratio or its related term are showing as below:

KPTI' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.23   Med: 1.07   Max: 4.7
Current: 0.37

During the past years, Karyopharm Therapeutics's highest Cyclically Adjusted PB Ratio was 4.70. The lowest was 0.23. And the median was 1.07.

KPTI's Cyclically Adjusted PB Ratio is ranked better than
78.32% of 641 companies
in the Biotechnology industry
Industry Median: 1.74 vs KPTI: 0.37

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Karyopharm Therapeutics's adjusted book value per share data for the three months ended in Dec. 2023 was $-1.185. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $2.88 for the trailing ten years ended in Dec. 2023.

Shiller PE for Stocks: The True Measure of Stock Valuation


Karyopharm Therapeutics Cyclically Adjusted PB Ratio Historical Data

The historical data trend for Karyopharm Therapeutics's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

* Premium members only.

Karyopharm Therapeutics Cyclically Adjusted PB Ratio Chart

Karyopharm Therapeutics Annual Data
Trend Dec14 Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only - - 2.10 1.09 0.30

Karyopharm Therapeutics Quarterly Data
Mar19 Jun19 Sep19 Dec19 Mar20 Jun20 Sep20 Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.09 1.26 0.59 0.43 0.30

Competitive Comparison of Karyopharm Therapeutics's Cyclically Adjusted PB Ratio

For the Biotechnology subindustry, Karyopharm Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Karyopharm Therapeutics's Cyclically Adjusted PB Ratio Distribution in the Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Karyopharm Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Karyopharm Therapeutics's Cyclically Adjusted PB Ratio falls into.



Karyopharm Therapeutics Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Karyopharm Therapeutics's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=1.06/2.88
=0.37

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Karyopharm Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2023 is calculated as:

For example, Karyopharm Therapeutics's adjusted Book Value per Share data for the three months ended in Dec. 2023 was:

Adj_Book=Book Value per Share/CPI of Dec. 2023 (Change)*Current CPI (Dec. 2023)
=-1.185/129.4194*129.4194
=-1.185

Current CPI (Dec. 2023) = 129.4194.

Karyopharm Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201403 4.865 99.695 6.316
201406 4.431 100.560 5.703
201409 6.985 100.428 9.001
201412 6.324 99.070 8.261
201503 7.721 99.621 10.030
201506 6.927 100.684 8.904
201509 6.177 100.392 7.963
201512 5.531 99.792 7.173
201603 4.928 100.470 6.348
201606 4.267 101.688 5.431
201609 4.202 101.861 5.339
201612 3.873 101.863 4.921
201703 3.302 102.862 4.155
201706 3.538 103.349 4.430
201709 2.994 104.136 3.721
201712 2.614 104.011 3.253
201803 1.923 105.290 2.364
201806 3.528 106.317 4.295
201809 2.820 106.507 3.427
201812 3.011 105.998 3.676
201903 1.993 107.251 2.405
201906 1.353 108.070 1.620
201909 0.955 108.329 1.141
201912 0.761 108.420 0.908
202003 2.273 108.902 2.701
202006 1.769 108.767 2.105
202009 1.139 109.815 1.342
202012 0.684 109.897 0.806
202103 -0.528 111.754 -0.611
202106 -1.104 114.631 -1.246
202109 -1.669 115.734 -1.866
202112 -1.052 117.630 -1.157
202203 -1.046 121.301 -1.116
202206 -1.458 125.017 -1.509
202209 -1.731 125.227 -1.789
202212 -0.147 125.222 -0.152
202303 -0.396 127.348 -0.402
202306 -0.623 128.729 -0.626
202309 -0.877 129.860 -0.874
202312 -1.185 129.419 -1.185

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.


Karyopharm Therapeutics  (NAS:KPTI) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Karyopharm Therapeutics Cyclically Adjusted PB Ratio Related Terms

Thank you for viewing the detailed overview of Karyopharm Therapeutics's Cyclically Adjusted PB Ratio provided by GuruFocus.com. Please click on the following links to see related term pages.


Karyopharm Therapeutics (Karyopharm Therapeutics) Business Description

Traded in Other Exchanges
Address
85 Wells Avenue, 2nd Floor, Newton, MA, USA, 02459
Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company pioneering novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma.
Executives
Richard A. Paulson director, officer: President and CEO 85 WELLS AVENUE, NEWTON MA 02459
Garen G Bohlin director C/O PRAECIS PHARMACEUTICALS INC, 830 WINTER STREET, WALTHAM MA 02451
Michael Mason officer: EVP, CFO, Treasurer 300 3RD STREET, CAMBRIDGE MA 02142
Michael Mano officer: SVP, General Counsel&Secretary 85 WELLS AVENUE, SUITE 210, NEWTON MA 02459
Sohanya Roshan Cheng officer: SVP Sales & Commercial Ops C/O KARYOPHARM THERAPEUTICS INC., 85 WELLS AVENUE, NEWTON MA 02459
Zhen Su director 85 WELLS AVENUE, SUITE 210, NEWTON MA 02459
Stuart Poulton officer: EVP, Chief Development Officer 85 WELLS AVENUE, NEWTON MA 02459
Reshma Rangwala officer: EVP & Chief Medical Officer RIVER OAKS TOWER, 3730 KIRBY DRIVE, SUITE 1200, HOUSTON TX 77098
Stephen Mitchener officer: SVP, Chief Business Officer C/O AXCELLA HEALTH INC., 840 MEMORIAL DRIVE, CAMBRIDGE MA 02139
Deepika Pakianathan director 160 BOVET ROAD, SUITE 408, C/O DELPHI VENTURES, SAN MATEO CA 94402
Ran Frenkel officer: EVP, WW Development Operations C/O KARYOPHARM THERAPEUTICS INC., 85 WELLS AVENUE, 2ND FLOOR, NEWTON MA 02459
Jatin Shah officer: EVP, Chief Medical Officer C/O KARYOPHARM THERAPEUTICS, INC., 85 WELLS AVENUE, NEWTON MA 02459
Sharon Shacham officer: C.S.O & Pres. of Res & Develop C/O KARYOPHARM THERAPEUTICS INC., 85 WELLS AVENUE, SECOND FLOOR, NEWTON MA 02459
Michael Kauffman director, officer: President, C.E.O., C.M.O. C/O KARYOPHARM THERAPEUTICS INC., 85 WELLS AVENUE, SECOND FLOOR, NEWTON MA 02459
Peter Honig director 3344 N. TORREY PINES COURT, SUITE 200, LA JOLLA CA 92037