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Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Shak StevenChief Scientific Officer2017-03-23Sell5,000331,103$31.26156.31.38331,103 (Direct)
Leber LauraChief Communication Officer2017-03-20Sell3,07214,627$31.8897.94-0.614,627 (Direct)
Cole G BradleyCOO2017-03-08Sell5,71039,528$31.55180.150.4439,528 (Direct)
Popovits Kimberly JPresident and CEO
(Click for the stocks that their CEOs have bought)
2017-03-06Sell5,000308,210$31.09155.451.9378,236 (Direct)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
200,851 (Held by the Popovits 2010 Trust)
Shak StevenChief Scientific Officer2017-02-23Sell5,000331,103$29.36146.87.94331,103 (Direct)
Febbo Phillip G.Chief Medical Officer2017-02-16Sell2,49520,644$30.0975.075.3220,644 (Direct)
Cole G BradleyCOO2017-02-15Sell5,00039,728$291459.2839,728 (Direct)
Shak StevenChief Scientific Officer2017-01-23Sell5,000327,207$27.28136.416.17327,207 (Direct)
Cole G BradleyCOO2017-01-10Sell5,00035,882$29.22146.18.4535,882 (Direct)
Cole G BradleyCOO2016-12-06Sell5,00035,882$30.61153.053.5335,882 (Direct)
Popovits Kimberly JPresident and CEO2016-12-05Sell5,000289,594$30.02150.15.5659,620 (Direct)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
200,851 (Held by the Popovits 2010 Trust)
Leber LauraChief Communication Officer2016-11-21Sell7,06814,331$31.73224.27-0.1314,331 (Direct)
Shak StevenChief Scientific Officer2016-11-10Sell5,000327,207$31.71158.55-0.06327,207 (Direct)
Cole G BradleyCOO2016-11-08Sell5,00035,426$29.68148.46.7735,426 (Direct)
Popovits Kimberly JPresident and CEO2016-11-03Sell5,313289,594$28.88153.449.7359,620 (Direct)
200,851 (Held by the Popovits 2010 Trust)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
Shak StevenChief Scientific Officer2016-10-11Sell5,000327,207$30.39151.954.28327,207 (Direct)
Cole G BradleyCOO2016-10-10Sell8,29035,426$30.59253.593.635,426 (Direct)
Vaughn James JChief Commercial Officer2016-10-06Sell3,00026,079$29.6889.046.7726,079 (Direct)
Shak StevenChief Scientific Officer2016-09-13Sell5,000327,207$26.83134.1518.11327,207 (Direct)
Cole G BradleyCOO2016-09-06Sell4,00035,426$27.41109.6415.6135,426 (Direct)
Shak StevenChief Scientific Officer2016-08-23Sell5,000327,207$27.24136.216.34327,207 (Direct)
BAKER FELIXDirector, 10% Owner2016-08-15Buy100,00011,841,478$27.02270217.28
318,623 (See footnote(,))
11,348,958 (See footnote(,,))
173,897 (See footnote(F1,))
Cole G BradleyCOO2016-08-11Sell5,00035,426$28.87144.359.7735,426 (Direct)
Vaughn James JChief Commercial Officer2016-08-08Sell3,00029,079$28.7486.2210.2629,079 (Direct)
Shak StevenChief Scientific Officer2016-07-19Sell5,000327,207$27.42137.115.57327,207 (Direct)
Cole G BradleyCOO2016-07-06Sell5,00035,426$26.64133.218.9635,426 (Direct)
Shak StevenChief Scientific Officer2016-06-21Sell5,000327,207$25.77128.8522.97327,207 (Direct)
Cole G BradleyCOO2016-06-09Sell5,00035,426$26.62133.119.0535,426 (Direct)
Vaughn James JChief Commercial Officer2016-06-06Sell1,99732,079$2855.9213.1832,079 (Direct)
Cole G BradleyCOO2016-05-16Sell5,00034,970$27.613814.8234,970 (Direct)
Febbo Phillip G.Chief Medical Officer2016-05-10Sell6,32415,013$27.2172.0116.5115,013 (Direct)
Vaughn James JChief Commercial Officer2016-05-09Sell2,00031,255$285613.1831,255 (Direct)
Shak StevenChief Scientific Officer2016-05-04Sell10,000326,383$25.43254.324.62326,383 (Direct)
Vaughn James JChief Commercial Officer2016-02-09Sell324,076$280.0813.1824,076 (Direct)
LIVINGSTON RANDALL SDirector2016-01-13Sell1,2506,149$32.1440.18-1.46,149 (Direct)
Cole G BradleyCOO2016-01-12Sell4,00027,428$31.69126.76027,428 (Direct)
Vaughn James JChief Commercial Officer2016-01-07Sell2,00024,076$33.6367.26-5.7724,076 (Direct)
Cole G BradleyCOO2015-12-08Sell4,00027,428$29.26117.048.327,428 (Direct)
Leber LauraChief Communication Officer2015-12-07Sell4,20012,959$29.33123.198.0512,959 (Direct)
Vaughn James JChief Commercial Officer2015-12-07Sell2,00024,076$29.3358.668.0524,076 (Direct)
Cole G BradleyCOO2015-11-10Sell4,00030,326$26.03104.1221.7430,326 (Direct)
Cole G BradleyCOO2015-09-09Sell9,66430,326$25.35244.9825.0130,326 (Direct)
Cole G BradleyCOO2015-07-07Sell4,00030,326$27.53110.1215.1130,326 (Direct)
Cole G BradleyCOO2015-06-09Sell4,00030,326$26.24104.9620.7730,326 (Direct)
Cole G BradleyCOO2015-05-12Sell4,00029,658$27.54110.1615.0729,658 (Direct)
Popovits Kimberly JPresident and CEO2015-04-13Sell3,000203,001$31.2893.841.31Link
Cole G BradleyCOO2015-04-07Sell4,00029,658$30.44121.764.1129,658 (Direct)
Popovits Kimberly JPresident and CEO2015-03-12Sell3,000204,101$31.9195.73-0.69Link
Cole G BradleyCOO2015-03-10Sell4,00029,658$31.84127.36-0.4729,658 (Direct)
Popovits Kimberly JPresident and CEO2015-02-12Sell3,000204,601$29.8689.586.13Link
Cole G BradleyCOO2015-02-10Sell4,00021,645$31.37125.481.0221,645 (Direct)
LIVINGSTON RANDALL SDirector2015-02-02Sell1,0006,149$31.9331.93-0.756,149 (Direct)
Popovits Kimberly JPresident and CEO2015-01-12Sell3,000204,601$33.46100.38-5.29Link
Popovits Kimberly JPresident and CEO2014-12-11Sell3,000204,601$32.9998.97-3.94Link
Cole G BradleyCOO2014-12-08Sell4,33621,645$32.52141.01-2.5521,645 (Direct)
Popovits Kimberly JPresident and CEO2014-11-12Sell4,300205,201$34.82149.73-8.99Link
Cole G BradleyCOO2014-11-10Sell4,00022,891$35.35141.4-10.3522,891 (Direct)
LIVINGSTON RANDALL SDirector2014-11-03Sell3,0006,149$36.24108.72-12.566,149 (Direct)
Popovits Kimberly JPresident and CEO2014-10-13Sell3,000205,201$30.7892.342.96Link
Cole G BradleyCOO2014-10-08Sell4,00022,891$28.77115.0810.1522,891 (Direct)
Popovits Kimberly JPresident and CEO2014-09-11Sell3,000205,201$29.8289.466.27Link
Cole G BradleyCOO2014-09-08Sell4,70022,891$30.09141.425.3222,891 (Direct)
Shak StevenEVP of R&D2014-08-14Sell13,348312,298$27.36365.215.83312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-08-12Sell3,000205,201$26.0778.2121.56Link
Popovits Kimberly JPresident and CEO2014-07-14Sell3,000205,201$26.5979.7719.18Link
Cole G BradleyCOO2014-07-08Sell2,30022,891$27.0562.2217.1522,891 (Direct)
Shak StevenEVP of R&D2014-07-01Sell7,000312,298$2718917.37312,298 (Direct)
Shak StevenEVP of R&D2014-06-12Sell7,000312,298$26.73187.1118.56312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-06-12Sell3,000271,289$26.178.321.42Link
Schorno Dean LCFO2014-06-10Sell4,00030,673$27.62110.4814.7424,524 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2014-06-09Sell2,33722,891$27.2963.7816.1222,891 (Direct)
Popovits Kimberly JPresident and CEO2014-05-12Sell3,000270,579$26.5479.6219.4Link
Schorno Dean LCFO2014-05-09Sell4,00029,963$25.09100.3626.3123,814 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Shak StevenEVP of R&D2014-04-14Sell7,000311,588$26.25183.7520.72311,588 (Direct)
Cole G BradleyCOO2014-04-08Sell3,00022,226$278117.3722,226 (Direct)
Shak StevenEVP of R&D2014-03-14Sell7,000311,588$28.36198.5211.74311,588 (Direct)
Cole G BradleyCOO2014-03-10Sell3,00022,226$27.7683.2814.1622,226 (Direct)
HIBBS KATHY LSVP & General Counsel2014-02-18Sell1,31215,787$27.8836.5813.6715,787 (Direct)
Shak StevenEVP of R&D2014-02-14Sell7,000311,588$27.38191.6615.74311,588 (Direct)
Cole G BradleyCOO2014-02-10Sell3,00024,789$278117.3724,789 (Direct)
Shak StevenEVP of R&D2014-01-15Sell7,000308,283$31.51220.570.57308,283 (Direct)
Popovits Kimberly JPresident and CEO2014-01-13Sell2,500261,190$30755.63Link
Cole G BradleyCOO2014-01-08Sell3,00018,369$28.1784.5112.518,369 (Direct)
Shak StevenEVP of R&D & CMO2013-12-17Sell14,000308,283$29.57413.987.17308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-12-12Sell2,5000$30.6876.73.29Link
Schorno Dean LCFO2013-12-09Sell3,00027,706$33.2599.75-4.6921,557 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-12-02Sell1,0006,149$34.9234.92-9.256,149 (Direct)
Popovits Kimberly JPresident and CEO2013-11-13Sell5,0000$34.58172.9-8.36Link
Schorno Dean LCFO2013-11-08Sell3,00027,585$33.36100.08-5.0121,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-11-06Sell2,86818,135$31.38900.9918,135 (Direct)
Shak StevenEVP of R&D & CMO2013-10-15Sell5,000308,283$29.67148.356.81308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-10-10Sell2,5000$30755.63Link
Cole G BradleyCOO2013-10-09Sell2,50018,135$29.9574.885.8118,135 (Direct)
Shak StevenEVP of R&D & CMO2013-09-18Sell5,000313,283$33.73168.65-6.05313,283 (Direct)
Popovits Kimberly JPresident and CEO2013-09-12Sell2,5000$34.3185.78-7.64Link
Cole G BradleyCOO2013-09-09Sell2,50018,135$32.5381.33-2.5818,135 (Direct)
Schorno Dean LCFO2013-09-06Sell4,00027,585$32.9131.6-3.6821,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-09-03Sell1,0006,149$31.4931.490.646,149 (Direct)
Shak StevenEVP of R&D & CMO2013-08-14Sell5,000318,283$32.98164.9-3.91318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-08-12Sell2,5000$33.0382.58-4.06Link
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-4.421,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-4.421,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-08-07Sell2,50019,135$33.6684.15-5.8519,135 (Direct)
Shak StevenEVP of R&D & CMO2013-07-23Sell5,000318,283$35.33176.65-10.3318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-07-12Sell5,0000$34.61173.05-8.44Link
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.24-6.2717,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.24-6.2717,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-07-08Sell2,50013,135$33.3383.33-4.9213,135 (Direct)
Shak StevenEVP of R&D & CMO2013-06-18Sell5,000323,283$33.52167.6-5.46323,283 (Direct)
Popovits Kimberly JPresident and CEO2013-06-12Sell5,0000$35.68178.4-11.18Link
Schorno Dean LCFO2013-06-10Sell4,00023,985$35.88143.52-11.6817,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-06-05Sell2,50013,135$36.4791.18-13.1113,135 (Direct)
BAKER FELIXDirector, 10% Owner2013-06-05Buy381,43213,288,253$36.1613792.58-12.36
1,730,777 (See Footnote)
11,241,654 (See Footnotes(F7,F14,F15))
301,215 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-06-03Buy179,58312,906,821$36.716592.49-13.67
1,690,226 (See Footnote)
10,909,066 (See Footnotes(F7,F14,F15))
292,922 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-06-03Sell1,0006,149$36.436.4-12.946,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-29Buy121,26612,727,238$36.894473.5-14.1
1,671,081 (See Footnote)
10,752,532 (See Footnotes(F7,F14,F15))
289,018 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-05-24Buy79,41714,257,273$36.932932.87-14.19
1,651,301 (See Footnote)
10,646,920 (See Footnotes(F7,F17,F18))
286,384 (See Footnotes(F9,F17,F18))
1,658,061 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-22Sell1,0007,087$37.4837.48-15.457,087 (Direct)
Shak StevenEVP of R&D & CMO2013-05-21Sell5,000327,380$37.19185.95-14.79327,380 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-16Buy71,43912,526,555$36.452603.95-13.06
1,649,473 (See Footnote)
10,577,816 (See Footnotes(F7,F14,F15))
284,659 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-05-15Sell1,3376,149$35.8347.9-11.556,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-14Buy240,42614,093,759$34.348256.23-7.72
1,638,643 (See Footnote)
10,515,769 (See Footnotes(F7,F17,F18))
283,112 (See Footnotes(F9,F17,F18))
1,641,628 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-13Sell1,2507,087$34.4243.03-7.937,087 (Direct)
Popovits Kimberly JPresident and CEO2013-05-13Sell5,0000$34.7173.5-8.67Link
Schorno Dean LCFO2013-05-09Sell4,00023,241$36.02144.08-12.0217,092 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-05-08Sell2,50012,540$35.9989.98-11.9512,540 (Direct)
Popovits Kimberly JPresident and CEO2013-04-23Sell2,5000$30755.63Link
Cole G BradleyCOO2013-04-03Sell2,50012,540$27.7969.4814.0312,540 (Direct)
Cole G BradleyCOO2013-03-06Sell2,50012,540$28.5771.4310.9212,540 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-21Buy49,08512,211,834$27.781363.5814.07
1,614,513 (See Footnote)
10,306,239 (See Footnotes(F7,F14,F15))
277,189 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
HIBBS KATHY LSVP & General Counsel2013-02-20Sell2,7167,087$28.1376.412.667,087 (Direct)
MYERS WOODROW A JRDirector2013-02-14Sell41,2502,891$28.41171.511.582,891 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-14Buy52,00012,162,749$28.481480.9611.27
1,609,152 (See Footnote)
10,263,580 (See Footnotes(F7,F14,F15))
276,124 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-02-11Buy116,36012,110,749$28.153275.5312.58
1,603,265 (See Footnote)
10,218,600 (See Footnotes(F7,F14,F15))
274,991 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-02-06Sell2,50014,085$28.0370.0813.0614,085 (Direct)
LIVINGSTON RANDALL SDirector2013-01-28Sell2,0006,149$28.7757.5410.156,149 (Direct)
Schorno Dean LCFO2013-01-09Sell2,62523,504$2873.513.1817,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-01-09Sell2,50014,085$27.8869.713.6714,085 (Direct)
Shak StevenEVP of R&D & CMO2012-12-18Sell5,000333,768$27.74138.714.24333,768 (Direct)
Popovits Kimberly JPresident and CEO2012-12-13Sell5,0000$27.79138.9514.03Link
Schorno Dean LCFO2012-12-11Sell3,00023,504$288413.1817,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2012-11-26Sell2,0006,149$27.8455.6813.836,149 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-21Buy229,30012,263,857$26.836152.1218.11288 (Direct)
271,800 (See Footnote)
1,589,551 (See Footnotes(F5,F14,F15))
10,117,174 (See Footnotes(F7,F14,F15))
271,806 (See Footnotes(F9,F14,F15))
13,238 (See Footnote(F9,F14,F15))
Shak StevenEVP of R&D & CMO2012-11-20Sell5,000338,768$26.94134.717.63338,768 (Direct)
COLELLA SAMUEL DDirector2012-11-20Sell30,61636,437$26.89823.2617.8536,437 (Direct)
0 (Versant Venture Capital I, L.P.)
0 (Versant Side Fund I, L.P.)
0 (Versant Affiliates Fund I-A, L.P.)
0 (Versant Affiliates Fund I-B, L.P.)
BAKER FELIXDirector, 10% Owner2012-11-14Buy103,16713,526$27.322818.5216288 (Direct)
13,238 (See Footnote)
Popovits Kimberly JPresident and CEO2012-11-14Sell5,0000$27.24136.216.34Link
BAKER FELIXDirector, 10% Owner2012-11-13Buy823,77213,526$27.8122909.113.95288 (Direct)
13,238 (See Footnote)
Schorno Dean LCFO2012-11-12Sell3,00023,504$288413.1817,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-11-08Sell2,50014,085$28.6271.5510.7314,085 (Direct)
Popovits Kimberly JPresident and CEO2012-10-16Sell10,0000$33.08330.8-4.2Link
Shak StevenEVP of R&D & CMO2012-10-16Sell5,000343,768$35.25176.25-10.1343,768 (Direct)
Schorno Dean LCFO2012-10-12Sell3,00023,504$33.79101.37-6.2117,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
HIBBS KATHY LSVP & General Counsel2012-10-11Sell1,25011,367$33.7842.23-6.1911,367 (Direct)
Cole G BradleyCOO2012-10-09Sell2,50014,085$34.887-8.9414,085 (Direct)
Shak StevenEVP of R&D & CMO2012-09-18Sell5,000348,768$33.76168.8-6.13348,768 (Direct)
Popovits Kimberly JPresident and CEO2012-09-13Sell5,0000$31.69158.450Link
Cole G BradleyCOO2012-09-06Sell2,50014,085$35.0187.53-9.4814,085 (Direct)
MYERS WOODROW A JRDirector2012-08-21Sell16,5002,236$35.2580.8-9.972,236 (Direct)
Shak StevenEVP of R&D & CMO2012-08-20Sell5,000353,768$34.99174.95-9.43353,768 (Direct)
Popovits Kimberly JPresident and CEO2012-08-13Sell10,0000$34.72347.2-8.73Link
Cole G BradleyCOO2012-08-08Sell2,50014,085$30.4976.233.9414,085 (Direct)
LIVINGSTON RANDALL SDirector2012-07-26Sell2,0006,149$35.971.8-11.736,149 (Direct)
Shak StevenChief Medical Officer2012-07-24Sell5,000358,768$34.24171.2-7.45358,768 (Direct)
Popovits Kimberly JPresident and CEO2012-07-13Sell7,1000$34.76246.8-8.83Link
Scott Randal WCEO, InVitae Corporation*2012-07-11Sell30,0000$35.391061.7-10.45Link
Cole G BradleyCOO2012-07-05Sell2,50014,085$35.9589.88-11.8514,085 (Direct)
Shak StevenChief Medical Officer2012-06-25Sell5,000363,768$33.25166.25-4.69363,768 (Direct)
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-5.01Link
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-5.01Link
Scott Randal WCEO, InVitae Corporation*2012-06-12Sell30,0000$33.541006.2-5.52Link
Cole G BradleyCOO2012-06-06Sell2,50013,507$33.9784.93-6.7113,507 (Direct)
Shak StevenChief Medical Officer2012-05-24Sell5,000367,849$33.8169-6.24367,849 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-22Buy167,4061,488,539$32.265400.52-1.77
1,488,539 (See Footnote)
COLELLA SAMUEL DDirector2012-05-18Sell26,294664,113$33.03868.49-4.0626,891 (Direct)
582,174 (Versant Venture Capital I, L.P.)
11,210 (Versant Side Fund I, L.P.)
13,222 (Colella Family Partners, L.P.)
10,414 (Versant Affiliates Fund I-A, L.P.)
20,202 (Versant Affiliates Fund I-B, L.P.)
BAKER JULIANDirector, 10% Owner2012-05-16Buy376,0591,488,539$33.8812740.88-6.46
1,488,539 (See Footnote)
Popovits Kimberly JPresident and CEO2012-05-16Sell10,0000$34.23342.3-7.42Link
Schorno Dean LCFO2012-05-15Sell1,00023,504$33.6933.69-5.9417,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER JULIANDirector, 10% Owner2012-05-11Buy114,8881,488,539$29.963442.045.77
1,488,539 (See Footnote)
Scott Randal WCEO, InVitae Corporation*2012-05-11Sell30,0000$30.22906.64.86Link
Cole G BradleyCOO2012-05-09Sell2,50013,507$28.8772.189.7713,507 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-08Buy195,70113,238$28.455567.6911.39
13,238 (See Footnote)
LIVINGSTON RANDALL SDirector2012-04-26Sell2,0006,149$28.2156.4212.346,149 (Direct)
Shak StevenChief Medical Officer2012-04-24Sell5,000372,849$27.93139.6513.46372,849 (Direct)
Popovits Kimberly JPresident and CEO2012-04-23Sell5,0000$27.79138.9514.03Link
Schorno Dean LCFO2012-04-16Sell1,00024,504$27.9827.9813.2618,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation*2012-04-11Sell20,0000$28.59571.810.84Link
Cole G BradleyCOO2012-04-04Sell2,50013,507$30.2875.74.6613,507 (Direct)
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.45.35377,849 (Direct)
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.355.39Link
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.355.39Link
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.45.35377,849 (Direct)
Schorno Dean LCFO2012-03-15Sell1,00025,504$31.0831.081.9619,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation2012-03-13Sell30,0000$31.05931.52.06Link
Cole G BradleyCOO2012-03-08Sell2,50013,507$29.9474.855.8513,507 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-08Buy4,5081,484,977$30.11135.745.25
1,484,977 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-08Buy1,099227,840$30.1133.095.25
227,840 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-08Buy41,5848,255,421$30.111252.095.25
8,255,421 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-05Buy261,7618,213,837$29.817803.16.31
8,213,837 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-05Buy6,923226,741$29.81206.376.31
226,741 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-05Buy31,3321,480,469$29.81934.016.31
1,480,469 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-29Buy6,476219,818$29.06188.199.05
219,818 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-29Buy245,0317,952,076$29.067120.69.05
7,952,076 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-29Buy29,7561,449,137$29.06864.719.05
1,449,137 (Through Partnership)
Popovits Kimberly JPresident and CEO2012-02-24Sell10,0000$28.528511.19Link
Shak StevenChief Medical Officer2012-02-23Sell5,000382,849$28.14140.712.62382,849 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-23Buy114,5187,707,045$28.063213.3812.94
7,707,045 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-23Buy3,022213,342$28.0684.812.94
213,342 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-23Buy13,3321,419,381$28.06374.112.94
1,419,381 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-16Buy33,1851,406,049$29.34973.658.01
1,406,049 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-16Buy7,213210,320$29.37211.857.9
210,320 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-16Buy272,9097,592,527$29.378015.347.9
7,592,527 (Through Partnership)
Schorno Dean LCFO2012-02-15Sell1,00026,504$28.7628.7610.1920,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2012-02-15Sell75526,749$28.7621.7110.1920,600 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.621.05Link
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-10Buy417,9157,319,618$26.3611016.2420.22
7,319,618 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-10Buy11,043203,107$26.36291.0920.22
203,107 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-10Buy66,5831,372,864$26.361755.1320.22
1,372,864 (Through Partnership)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.621.05Link
Cole G BradleyCOO2012-02-08Sell2,50014,450$26.4766.1819.7214,450 (Direct)
LIVINGSTON RANDALL SDirector2012-01-26Sell2,0006,149$27.5155.0215.196,149 (Direct)
Popovits Kimberly JPresident and CEO2012-01-25Sell5,0000$26.42132.119.95Link
Popovits Kimberly JPresident and CEO2012-01-24Sell5,0000$26.62133.119.05Link
Shak StevenChief Medical Officer2012-01-24Sell5,000382,778$26.74133.718.51382,778 (Direct)
Schorno Dean LCFO2012-01-17Sell1,00024,049$282813.1817,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-01-12Sell2,5007,750$27.5468.8515.077,750 (Direct)
Scott Randal WExecutive Chairman2012-01-11Sell20,0000$27.46549.215.4Link
Shak StevenChief Medical Officer2011-12-22Sell5,000387,778$26.03130.1521.74387,778 (Direct)
Scott Randal WExecutive Chairman2011-12-13Sell20,0000$27.29545.816.12Link
Cole G BradleyCOO2011-12-06Sell2,5007,750$28.5971.4810.847,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-12-05Buy3,152192,064$28.1288.6312.7
192,064 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-12-05Buy45,9771,306,281$27.661271.7214.57
1,306,281 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-12-05Buy117,7516,901,703$28.123311.1612.7
6,901,703 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-23Buy5,5311,260,304$25.91143.3122.31
1,260,304 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-23Buy5,750188,912$25.94149.1622.17
188,912 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-23Buy193,7396,783,952$25.915019.7822.31
6,783,952 (Through Partnership)
Shak StevenChief Medical Officer2011-11-22Sell5,000392,778$26.07130.3521.56392,778 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-16Buy64,5976,590,213$27.711789.9814.36
6,590,213 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-16Buy2,550183,162$27.7170.6614.36
183,162 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-16Buy4581,254,773$27.3512.5315.87
1,254,773 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-14Buy10,106180,612$27.23275.1916.38
180,612 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-14Buy249,3756,525,616$27.236790.4816.38
6,525,616 (Through Partnership)
Scott Randal WExecutive Chairman2011-11-11Sell20,0000$27.24544.816.34Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-09Buy5421,254,315$26.7914.5218.29
1,254,315 (Through Partnership)
Cole G BradleyCOO2011-11-08Sell2,5007,750$26.666.519.147,750 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-07Buy209,5126,276,241$25.945434.7422.17
6,276,241 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-07Buy8,847170,506$25.94229.4922.17
170,506 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-03Buy1201,253,773$24.482.9429.45
1,253,773 (Through Partnership)
LIVINGSTON RANDALL SDirector2011-10-27Sell2,0006,149$22.0844.1643.526,149 (Direct)
Shak StevenChief Medical Officer2011-10-24Sell5,000392,778$21.76108.845.63392,778 (Direct)
Scott Randal WExecutive Chairman2011-10-11Sell20,0000$22.83456.638.81Link
Cole G BradleyCOO2011-10-06Sell5,0007,750$22.31111.5542.047,750 (Direct)
Scott Randal WExecutive Chairman2011-09-13Sell20,0000$20.81416.252.28Link
Cole G BradleyCOO2011-09-06Sell2,5007,750$22.0855.243.527,750 (Direct)
Shak StevenChief Medical Officer2011-08-24Sell5,000392,778$23.02115.137.66392,778 (Direct)
Scott Randal WExecutive Chairman2011-08-11Sell20,0000$24.44488.829.66Link
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.1525.467,750 (Direct)
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.1525.467,750 (Direct)
LIVINGSTON RANDALL SDirector2011-07-27Sell2,0006,149$26.4552.919.816,149 (Direct)
Shak StevenChief Medical Officer2011-07-25Sell5,000392,778$27.61138.0514.78392,778 (Direct)
Scott Randal WExecutive Chairman2011-07-12Sell20,0001,503,444$27.36547.215.831,491,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Cole G BradleyCOO2011-07-06Sell5,0007,750$27.74138.714.247,750 (Direct)
Shak StevenChief Medical Officer2011-06-23Sell5,000392,778$27.12135.616.85392,778 (Direct)
Schorno Dean LCFO2011-06-15Sell1,00025,049$25.9125.9122.3118,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-06-13Sell20,0001,523,444$25.69513.823.361,511,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-09Buy119194,415$26.193.1221
194,415 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-06-09Buy4,388161,659$26.19114.9221
161,659 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-09Buy203,6526,059,449$26.25335.6820.95
6,059,449 (Through Partnership)
Cole G BradleyCOO2011-06-06Sell2,5007,750$26.1865.4521.057,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-06-01Buy4,631157,271$27.34126.6115.91
157,271 (Through Partnership)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-01Buy112194,296$27.353.0615.87
194,296 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-01Buy181,6935,855,797$27.354969.315.87
5,855,797 (Through Partnership)
Shak StevenChief Medical Officer2011-05-25Sell5,000392,778$25.55127.7524.03392,778 (Direct)
Schorno Dean LCFO2011-05-12Sell1,00026,049$26.4826.4819.6819,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-05-11Sell20,0000$26.66533.218.87Link
Cole G BradleyCOO2011-05-09Sell2,5007,750$25.9364.8322.217,750 (Direct)
LIVINGSTON RANDALL SDirector2011-04-27Sell2,0000$26.0452.0821.7Link
Shak StevenChief Medical Officer2011-04-25Sell5,0000$25.38126.924.86Link
Popovits Kimberly JPresident and CEO2011-04-15Sell8,0000$25.49203.9224.32Link
Schorno Dean LCFO2011-04-14Sell1,0000$25.3225.3225.16Link
Scott Randal WExecutive Chairman2011-04-12Sell20,0000$25.96519.222.07Link
Cole G BradleyCOO2011-04-06Sell5,0000$26.91134.5517.76Link
Shak StevenChief Medical Officer2011-03-24Sell5,0000$24.45122.2529.61Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.3230.47Link
Schorno Dean LCFO2011-03-15Sell1,0000$23.7923.7933.21Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.3230.47Link
Scott Randal WExecutive Chairman2011-03-11Sell20,0000$25.62512.423.69Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-10Buy70,8560$26.031844.3821.74Link
Cole G BradleyCOO2011-03-08Sell2,5000$25.2363.0825.6Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-08Buy9,6480$25.06241.7826.46Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-08Buy349,5660$25.068760.1226.46Link
COLELLA SAMUEL DDirector2011-03-03Sell34,3200$25.45873.4424.52Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-02Buy160,3370$25.694119.0623.36Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-02Buy4,4260$25.69113.723.36Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-02-25Buy158,3550$23.393703.9235.49Link
14159 capital (GP), LLCDirector, 10% Owner2011-02-25Buy4,3700$23.39102.2135.49Link
Shak StevenChief Medical Officer2011-02-24Sell5,0000$23.27116.3536.18Link
Schorno Dean LCFO2011-02-15Sell1,0000$22.5122.5140.78Link
Popovits Kimberly JPresident and CEO2011-02-15Sell8,0000$22.51180.0840.78Link
Scott Randal WExecutive Chairman2011-02-11Sell20,0000$22.244442.75Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,0000$21.15169.249.83Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,000309,424$21.15169.249.83Link
Schorno Dean LCFO2011-01-13Sell1,27626,149$21.0626.8750.47Link
Scott Randal WExecutive Chairman2011-01-11Sell20,0001,642,410$21.73434.645.84Link
Cole G BradleyCOO2011-01-06Sell5,0001,000$22.13110.6543.2Link
Popovits Kimberly JPresident and CEO2010-12-16Sell8,000310,624$22.71181.6839.54Link
Scott Randal WExecutive Chairman2010-12-13Sell20,0001,696,410$22.46449.241.1Link
Cole G BradleyCOO & CFO2010-12-13Sell2,5001,000$22.6456.639.97Link
Popovits Kimberly JPresident and CEO2010-11-16Sell8,000310,624$17.514081.09Link
Cole G BradleyCOO & CFO2010-11-11Sell2,5001,000$18.0445.175.67Link
Scott Randal WExecutive Chairman2010-11-11Sell20,0001,666,410$18.27365.473.45Link
Scott Randal WExecutive Chairman2010-10-12Sell20,0001,686,410$13.95279127.17Link
Popovits Kimberly JPresident and CEO2010-09-15Sell7,734310,624$15.1116.78109.87Link
Scott Randal WExecutive Chairman2010-09-13Sell20,0001,706,410$14.87297.4113.11Link
Cole G BradleyCOO & CFO2010-09-13Sell2,5001,000$15.0137.53111.13Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-09Buy145134,196$14.812.15113.98Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-09Buy5,2614,934,990$14.8177.92113.98Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-02Buy65,4664,929,729$14.46946.64119.16Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-02Buy1,807134,051$14.4626.13119.16Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-30Buy3,415132,244$14.3749.07120.53Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-30Buy123,7114,864,263$14.371777.73120.53Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-23Buy150,4694,740,552$14.522184.81118.25Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-23Buy4,153128,829$14.5260.3118.25Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-18Buy530124,676$14.997.94111.41Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-18Buy19,1874,590,083$14.99287.61111.41Link
Popovits Kimberly JPresident and CEO2010-08-17Sell8,000288,116$15.07120.56110.29Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-13Buy2,924124,146$14.8543.42113.4Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-13Buy105,9104,570,896$14.851572.76113.4Link
Cole G BradleyCOO & CFO2010-08-12Sell2,5001,000$1537.5111.27Link
Scott Randal WExecutive Chairman2010-08-11Sell20,0001,726,410$14.71294.2115.43Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-10Buy164,2424,464,986$14.612399.58116.91Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-10Buy4,533121,222$14.6166.23116.91Link
Baker JoffreChief Scientific Officer2010-08-09Sell4,629163,088$14.7568.28114.85Link
Scott Randal WExecutive Chairman2010-07-13Sell20,0001,746,410$12.81256.2147.38Link
Baker JoffreChief Scientific Officer2010-07-07Sell4,629167,717$13.0560.41142.84Link
Scott Randal WExecutive Chairman2010-06-11Sell20,0001,766,410$14.15283123.96Link
Baker JoffreChief Scientific Officer2010-06-10Sell4,629172,346$14.0565.04125.55Link
Popovits Kimberly JPresident and CEO2010-05-17Sell8,000310,624$15.78126.24100.82Link
Cole G BradleyCOO & CFO2010-05-12Sell2,5001,000$15.8739.6899.68Link
Scott Randal WExecutive Chairman2010-05-11Sell20,0001,776,410$15.61312.2103.01Link
Baker JoffreChief Scientific Officer2010-05-10Sell4,629176,975$15.5171.8104.32Link
Scott Randal WExecutive Chairman2010-04-13Sell20,0001,796,410$16.87337.487.85Link
Cole G BradleyCOO & CFO2010-04-12Sell5,0001,000$16.984.587.51Link
Baker JoffreChief Scientific Officer2010-04-12Sell4,629181,604$16.8878.1487.74Link
Popovits Kimberly JPresident and CEO2010-03-16Sell20,000288,116$19.4538962.93Link
Scott Randal WExecutive Chairman2010-03-11Sell20,0001,800,646$19.338664.2Link
Cole G BradleyCOO & CFO2010-03-11Sell2,5001,000$19.3948.4863.43Link
COLELLA SAMUEL DDirector2010-03-10Sell106,70085,050$19.452075.3262.93Link
Baker JoffreChief Scientific Officer2010-03-08Sell4,629150,120$19.8391.7959.81Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-19Buy3,645116,689$17.0562.1585.87Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-19Buy132,0704,300,744$17.052251.7985.87Link
Scott Randal WExecutive Chairman2010-02-11Sell20,0001,830,646$17.23344.683.92Link
Cole G BradleyCOO & CFO2010-02-11Sell2,5001,000$17.5143.7880.98Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-10Buy9,437113,044$17.01160.5286.3Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-10Buy341,8544,168,674$17.015814.9486.3Link
Baker JoffreChief Scientific Officer2010-02-09Sell4,629145,491$17.1479.3484.89Link
Cole G BradleyCOO & CFO2010-01-12Sell5,0001,000$17.2586.2583.71Link
Baker JoffreChief Scientific Officer2010-01-11Sell4,629150,120$17.4780.8781.4Link
Shak StevenChief Medical Officer2009-12-21Sell5,000388,278$20.12100.657.5Link
Popovits Kimberly JPresident and CEO2009-12-15Sell5,000313,506$20.39101.9555.42Link
Cole G BradleyCOO & CFO2009-12-14Sell2,0001,000$20.4240.8455.19Link
Scott Randal WExecutive Chairman2009-12-11Sell12,0001,880,646$20.24242.8856.57Link
Baker JoffreChief Scientific Officer2009-12-08Sell4,629154,749$20.2693.7856.42Link
Popovits Kimberly JPresident and CEO2009-11-17Sell20,000318,506$19.21384.264.97Link
Cole G BradleyCOO & CFO2009-11-12Sell6653,000$20.0413.3358.13Link
Scott Randal WExecutive Chairman2009-11-11Sell12,0001,892,646$19.99239.8858.53Link
Baker JoffreChief Scientific Officer2009-11-10Sell4,629159,378$2092.5858.45Link
Shak StevenChief Medical Officer2009-10-20Sell5,000393,278$20.65103.2553.46Link
Popovits Kimberly JPresident and CEO2009-10-15Sell5,000338,506$20.42102.155.19Link
Scott Randal WExecutive Chairman2009-10-13Sell12,0001,904,646$20.66247.9253.39Link
Baker JoffreChief Scientific Officer2009-10-07Sell4,629164,007$21.179849.69Link
Shak StevenChief Medical Officer2009-09-22Sell5,000398,278$21.13105.6549.98Link
Popovits Kimberly JPresident and CEO2009-09-15Sell5,000343,506$20.73103.6552.87Link
Scott Randal WExecutive Chairman2009-09-11Sell12,0001,916,646$20.67248.0453.31Link
Baker JoffreChief Scientific Officer2009-09-04Sell4,629168,636$20.1293.1457.5Link
Shak StevenChief Medical Officer2009-08-25Sell5,000403,278$20.77103.8552.58Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-17Buy1,839103,607$19.9836.7458.61Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-17Buy66,6303,826,820$19.981331.2758.61Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-17Buy34194,184$19.980.6858.61Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-17Buy11,6571,253,653$19.98232.9158.61Link
Popovits Kimberly JPresident and CEO2009-08-17Sell5,000348,506$19.5397.6562.26Link
Cole G BradleyCOO & CFO2009-08-13Sell5,0003,000$2010058.45Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-12Buy15,8771,241,996$19.49309.4462.6Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-12Buy45194,150$19.50.8862.51Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-12Buy90,7543,760,190$19.491768.862.6Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-12Buy2,508101,768$19.4948.8862.6Link
Scott Randal WExecutive Chairman2009-08-11Sell12,0001,928,646$19.42233.0463.18Link
Baker JoffreChief Scientific Officer2009-08-10Sell4,629173,265$19.4890.1762.68Link
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.1197.94
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.1197.94
Scott Randal WExecutive Chairman2009-06-11Sell6,0001,940,646$18.27109.6273.45
Baker JoffreChief Scientific Officer2009-06-08Sell4,629182,523$17.6981.8979.14
Shak StevenChief Medical Officer2009-05-26Sell5,000408,278$199566.79
14159 capital (GP), LLCDirector, 10% Owner2009-05-21Buy1,10899,260$17.9719.9176.35
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-21Buy90194,161$17.971.6276.35
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-21Buy39,7783,669,436$17.97714.8176.35
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-21Buy25194,105$17.970.4576.35
Popovits Kimberly JPresident and CEO2009-05-15Sell5,000353,506$20.12100.657.5
Scott Randal WExecutive Chairman2009-05-12Sell12,0001,946,646$19.46233.5262.85
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-11Buy88194,080$19.551.7262.1
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-11Buy312194,071$19.556.162.1
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-11Buy137,4663,629,658$19.552687.4662.1
14159 capital (GP), LLCDirector, 10% Owner2009-05-11Buy3,82798,152$19.5574.8262.1
Baker JoffreChief Scientific Officer2009-05-08Sell4,629187,152$19.7291.2860.7
Scott Randal WExecutive Chairman2009-04-14Sell12,0001,958,646$25.47305.6424.42
Baker JoffreChief Scientific Officer2009-04-01Sell4,629191,781$25.27116.9725.41
Scott Randal WExecutive Chairman2009-03-11Sell12,0001,970,646$19.4232.863.35
Baker JoffreChief Scientific Officer2009-03-03Sell4,629196,410$19.1388.5565.66
Cole G BradleyCOO & CFO2009-02-17Sell5,0003,000$21.52107.647.26
Baker JoffreChief Scientific Officer2009-02-12Sell4,629201,039$20.695.3653.83
Baker JoffreChief Scientific Officer2009-02-12Sell4,62922,226$20.695.3653.83
Scott Randal WExecutive Chairman, Director2009-02-11Sell12,0001,982,646$20.85250.251.99
Baker JoffreChief Scientific Officer2009-01-12Sell4,62926,855$19.4189.8563.27
Shak StevenChief Medical Officer2008-12-22Sell100413,278$20.172.0257.11
Baker JoffreChief Scientific Officer2008-12-10Sell4,629205,668$19.2589.1164.62
Baker JoffreChief Scientific Officer2008-12-10Sell4,62931,484$19.2589.1164.62
Scott Randal WCEO, Director2008-12-09Sell12,0001,955,298$18.4220.872.23
Baker JoffreChief Scientific Officer2008-11-12Sell4,629210,297$19.8791.9859.49
Baker JoffreChief Scientific Officer2008-11-12Sell4,62936,113$19.8791.9859.49
Scott Randal WCEO, Director2008-11-11Sell12,0001,967,298$20.05240.658.05
Cole G BradleyEVP & CFO2008-11-10Sell10,0004,000$20.17201.757.11
Scott Randal WCEO, Director2008-10-14Sell12,0001,979,298$20.36244.3255.65
Baker JoffreChief Scientific Officer2008-10-01Sell9,25840,742$22.51208.440.78
Shak StevenChief Medical Officer2008-09-24Sell5,000413,378$22.67113.3539.79
Scott Randal WCEO, Director2008-09-16Sell12,0001,991,298$21.79261.4845.43
Shak StevenChief Medical Officer2008-08-26Sell5,000418,378$22.93114.6538.2
Baker JoffreChief Scientific Officer2008-08-26Sell4,629214,926$22.69105.0339.67
Cole G BradleyEVP & CFO2008-08-18Sell9,2984,000$23.67220.0833.88
Popovits Kimberly JPresident and COO2008-08-15Sell25,000358,506$24.2460630.73
Scott Randal WCEO, Director2008-08-12Sell12,0002,003,298$23.76285.1233.38
Scott Randal WCEO, Director2008-07-15Sell12,0002,015,298$2125250.9
Baker JoffreChief Scientific Officer2008-07-01Sell4,629219,555$19.2689.1564.54
Shak StevenChief Medical Officer2008-06-24Sell100423,378$20258.45
Scott Randal WCEO, Director2008-06-10Sell12,0002,027,298$19.92239.0459.09
Baker Brothers Life Sciences CDirector, 10% Owner2008-06-09Buy320,9833,492,192$19.916390.7759.17
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-06-09Buy76,0151,226,119$19.911513.4659.17
14159 capital (GP), LLCDirector, 10% Owner2008-06-09Buy10,29994,325$19.91205.0559.17
Baker JoffreChief Scientific Officer2008-06-02Sell4,629228,813$17.9983.2876.15
Scott Randal WCEO, Director2008-05-13Sell12,0002,039,298$18.7522569.01
Baker JoffreChief Scientific Officer2008-05-08Sell4,629233,442$19.2789.264.45
Scott Randal WCEO, Director2008-04-15Sell12,0002,051,298$17.22206.6484.03
Scott Randal WCEO, Director2008-03-11Sell12,0002,063,298$18.84226.0868.21
Baker JoffreChief Scientific Officer2008-03-05Sell4,629242,700$20.4894.854.74
Shak StevenChief Medical Officer2008-02-26Sell5,000423,478$20.23101.1556.65
Cole G BradleyEVP & CFO2008-02-19Sell9,0008,298$22.58203.2240.35
Scott Randal WCEO, Director2008-02-12Sell12,0002,075,298$23.01276.1237.72
Baker JoffreChief Scientific Officer2008-02-11Sell4,629247,329$22.94106.1938.14
Scott Randal WCEO, Director2008-01-15Sell12,0002,087,298$25.54306.4824.08
Baker JoffreChief Scientific Officer2008-01-02Sell4,629251,958$22.66104.8939.85
Baker JoffreChief Scientific Officer2007-12-03Sell4,6290$23.1106.9337.19
Popovits Kimberly JPresident and COO2007-11-27Sell6,655383,506$22146.4144.05
Scott Randal WCEO, Director2007-11-09Sell12,0002,111,299$23.07276.8437.36
Baker JoffreChief Scientific Officer2007-11-08Sell4,629265,845$23.21107.4436.54
Scott Randal WCEO2007-10-09Sell12,0002,123,299$20.16241.9257.19
Baker JoffreChief Scientific Officer2007-10-01Sell4,629270,474$19.8491.8459.73
Scott Randal WCEO, Director2007-09-11Sell12,0002,135,299$19.7236.460.86
Scott Randal WCEO2007-09-11Sell12,0002,135,299$19.69236.2860.94
Baker JoffreChief Scientific Officer2007-09-10Sell4,629275,103$19.5790.5961.93
Goldberg Michael DDirector2007-08-23Buy5,3505,350$18.76100.3768.92
Scott Randal WCEO2007-08-15Sell12,0002,147,299$19.91238.9259.17
Baker JoffreChief Scientific Officer2007-08-08Sell4,629279,732$19.4489.9963.01
Scott Randal WCEO2007-07-18Sell12,0002,159,299$21.18254.1649.62
Baker JoffreChief Scientific Officer2007-07-02Sell4,629284,361$19.018866.7
Scott Randal WCEO2007-06-19Sell12,0002,171,299$19.16229.9265.4
Baker JoffreChief Scientific Officer2007-06-01Sell4,629288,990$17.5681.2980.47
Baker Bros. Capital (GP), LLCDirector2007-05-30Buy545193,992$16.328.8994.18
Baker Biotech Capital (GP), LLDirector2007-05-30Buy81,1811,150,104$16.321324.8794.18
Baker Brothers Life Sciences CDirector2007-05-30Buy214,0993,171,209$16.323494.194.18
14159 capital (GP), LLCDirector2007-05-30Buy6,80784,026$16.32111.0994.18
14159 capital (GP), LLCDirector2007-05-24Buy16,26177,219$16.59269.7791.02
Baker Brothers Life Sciences CDirector2007-05-24Buy511,5532,957,110$16.598486.6691.02
Baker Biotech Capital (GP), LLDirector2007-05-24Buy193,9661,068,923$16.593217.991.02
Baker Bros. Capital (GP), LLCDirector2007-05-24Buy1,303193,447$16.5921.6291.02
14159 capital (GP), LLCDirector2007-05-21Buy22,49160,958$15.5348.61104.45
14159 capital (GP), LLCDirector2007-05-21Buy160,958$15.50.02104.45
Baker Brothers Life Sciences CDirector2007-05-21Buy707,4582,445,557$15.510965.6104.45
Baker Biotech Capital (GP), LLDirector2007-05-21Buy268,248874,957$15.54157.84104.45
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.95104.45
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.95104.45
Scott Randal WCEO2007-05-08Sell12,0002,183,299$16.62199.4490.67
Baker JoffreChief Scientific Officer2007-05-08Sell4,629293,619$16.3175.594.3
Scott Randal WCEO2007-04-10Sell12,0002,195,299$17.27207.2483.5
Baker JoffreChief Scientific Officer2007-04-02Sell4,629298,248$17.1679.4384.67
Baker / Tisch Capital (GP), LLDirector2007-03-09Buy3,181193,759$18.2858.1573.36
Baker Bros. Capital (GP), LLCDirector2007-03-09Buy376190,341$18.286.8773.36
Baker Biotech Capital (GP), LLDirector2007-03-09Buy62,325606,709$18.281139.373.36
Baker Brothers Life Sciences CDirector2007-03-09Buy168,5601,738,099$18.283081.2873.36
14159 capital (GP), LLCDirector2007-03-09Buy5,37538,467$18.2898.2673.36
Scott Randal WCEO2007-03-06Sell12,0002,207,299$18.35220.272.7
Baker Bros. Capital (GP), LLCDirector2007-03-02Buy119189,965$18.092.1575.18
14159 capital (GP), LLCDirector2007-03-02Buy1,70733,092$18.0930.8875.18
Baker / Tisch Capital (GP), LLDirector2007-03-02Buy1,072190,578$18.119.475.08
Baker Biotech Capital (GP), LLDirector2007-03-02Buy19,795544,384$18.09358.0975.18
Baker Brothers Life Sciences CDirector2007-03-02Buy53,5331,569,539$18.09968.4175.18
Baker JoffreChief Scientific Officer2007-03-01Sell4,629302,877$18.1884.1674.31
MYERS WOODROW A JRDirector2007-02-21Buy2,00012,000$19.6339.2661.44
Baker Brothers Life Sciences CDirector2007-02-16Buy25,4121,516,006$18.54471.1470.93
Baker Biotech Capital (GP), LLDirector2007-02-16Buy9,396524,589$18.54174.270.93
Baker / Tisch Capital (GP), LLDirector2007-02-16Buy525189,506$18.549.7370.93
14159 capital (GP), LLCDirector2007-02-16Buy81131,385$18.5415.0470.93
Baker Bros. Capital (GP), LLCDirector2007-02-16Buy56189,846$18.541.0470.93
Baker Bros. Capital (GP), LLCDirector2007-02-14Buy579189,790$18.2510.5773.64
Baker / Tisch Capital (GP), LLDirector2007-02-14Buy5,346188,981$18.2597.5673.64
Baker Biotech Capital (GP), LLDirector2007-02-14Buy95,783515,193$18.251748.0473.64
14159 capital (GP), LLCDirector2007-02-14Buy8,25630,574$18.25150.6773.64
Baker Brothers Life Sciences CDirector2007-02-14Buy259,0441,490,594$18.254727.5573.64
Scott Randal WCEO2007-02-13Sell12,0002,219,299$18.12217.4474.89
Baker JoffreChief Scientific Officer2007-02-08Sell4,629307,506$18.9787.8167.05
Baker / Tisch Capital (GP), LLDirector2006-12-06Buy642183,635$21.5813.8546.85
Baker Brothers Life Sciences CDirector2006-12-06Buy34,1731,231,550$21.58737.4546.85
14159 capital (GP), LLCDirector2006-12-06Buy1,12022,318$21.5824.1746.85
Baker Biotech Capital (GP), LLDirector2006-12-06Buy12,237419,410$21.58264.0746.85
MYERS WOODROW A JRDirector2006-12-05Buy10,00010,000$21.97219.744.24
Baker / Tisch Capital (GP), LLDirector2006-12-05Buy9,096182,993$20.6187.3853.83
Baker Biotech Capital (GP), LLDirector2006-12-05Buy173,441407,173$20.63572.8853.83
14159 capital (GP), LLCDirector2006-12-05Buy15,88021,198$20.6327.1353.83
Baker Brothers Life Sciences CDirector2006-12-05Buy484,3331,197,377$20.69977.2653.83
14159 capital (GP), LLCDirector2006-09-08Buy5,3185,318$14.0574.72125.55Link
Baker Biotech Capital (GP), LLDirector2006-09-08Buy75,246233,732$14.051057.21125.55Link
Baker Brothers Life Sciences CDirector2006-09-08Buy237,236713,044$14.053333.17125.55Link
Baker Biotech Capital III (GP)10% Owner2005-10-04Buy136,316252,529$121635.79164.08Link
Baker Biotech Capital II (GP),10% Owner2005-10-04Buy38,684181,478$12464.21164.08Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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