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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Randal W. Scott,PhDN/A1,185,1173.59%2012-07-10
Steven Shak,M.D.N/A326,3830.99%2016-02-15
Joffre B. Baker,PhDN/A132,8460.4%2012-02-15
Dr. Fred E. Cohen,M.D.,D.Phil.N/A64,5200.2%2016-04-01
Kimberly J. PopovitsN/A58,7960.18%2016-02-15
G. Bradley ColeCOO34,9700.11%2016-02-15
Mr. James J. VaughnChief Commercial Officer31,255less than 0.1%2016-02-15
Mr. Frederic PlaN/A25,618less than 0.1%2016-02-15
Mr. Dean L. SchornoN/A24,524less than 0.1%2014-06-10
Brook H. ByersN/A23,951less than 0.1%2010-12-09

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Vaughn James JChief Commercial Officer2016-02-09Sell324,076$280.1-7.2124,076 (Direct)
LIVINGSTON RANDALL SDirector2016-01-13Sell1,2506,149$32.1440.2-19.176,149 (Direct)
Cole G BradleyCOO2016-01-12Sell4,00027,428$31.69126.8-18.0227,428 (Direct)
Vaughn James JChief Commercial Officer2016-01-07Sell2,00024,076$33.6367.3-22.7524,076 (Direct)
Cole G BradleyCOO2015-12-08Sell4,00027,428$29.26117-11.2127,428 (Direct)
Leber LauraChief Communication Officer2015-12-07Sell4,20012,959$29.33123.2-11.4212,959 (Direct)
Vaughn James JChief Commercial Officer2015-12-07Sell2,00024,076$29.3358.7-11.4224,076 (Direct)
Cole G BradleyCOO2015-11-10Sell4,00030,326$26.03104.1-0.1930,326 (Direct)
Cole G BradleyCOO2015-09-09Sell9,66430,326$25.352452.4930,326 (Direct)
Cole G BradleyCOO2015-07-07Sell4,00030,326$27.53110.1-5.6330,326 (Direct)
Cole G BradleyCOO2015-06-09Sell4,00030,326$26.24105-0.9930,326 (Direct)
Cole G BradleyCOO2015-05-12Sell4,00029,658$27.54110.2-5.6629,658 (Direct)
Popovits Kimberly JPresident and CEO
(Click for the stocks that their CEOs have bought)
2015-04-13Sell3,000203,001$31.2893.8-16.94Link
Cole G BradleyCOO2015-04-07Sell4,00029,658$30.44121.8-14.6529,658 (Direct)
Popovits Kimberly JPresident and CEO2015-03-12Sell3,000204,101$31.9195.7-18.58Link
Cole G BradleyCOO2015-03-10Sell4,00029,658$31.84127.4-18.429,658 (Direct)
Popovits Kimberly JPresident and CEO2015-02-12Sell3,000204,601$29.8689.6-12.99Link
Cole G BradleyCOO2015-02-10Sell4,00021,645$31.37125.5-17.1821,645 (Direct)
LIVINGSTON RANDALL SDirector2015-02-02Sell1,0006,149$31.9331.9-18.636,149 (Direct)
Popovits Kimberly JPresident and CEO2015-01-12Sell3,000204,601$33.46100.4-22.36Link
Popovits Kimberly JPresident and CEO2014-12-11Sell3,000204,601$32.9999-21.25Link
Cole G BradleyCOO2014-12-08Sell4,33621,645$32.52141-20.1121,645 (Direct)
Popovits Kimberly JPresident and CEO2014-11-12Sell4,300205,201$34.82149.7-25.39Link
Cole G BradleyCOO2014-11-10Sell4,00022,891$35.35141.4-26.5122,891 (Direct)
LIVINGSTON RANDALL SDirector2014-11-03Sell3,0006,149$36.24108.7-28.316,149 (Direct)
Popovits Kimberly JPresident and CEO2014-10-13Sell3,000205,201$30.7892.3-15.59Link
Cole G BradleyCOO2014-10-08Sell4,00022,891$28.77115.1-9.722,891 (Direct)
Popovits Kimberly JPresident and CEO2014-09-11Sell3,000205,201$29.8289.5-12.88Link
Cole G BradleyCOO2014-09-08Sell4,70022,891$30.09141.4-13.6622,891 (Direct)
Shak StevenEVP of R&D2014-08-14Sell13,348312,298$27.36365.2-5.04312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-08-12Sell3,000205,201$26.0778.2-0.35Link
Popovits Kimberly JPresident and CEO2014-07-14Sell3,000205,201$26.5979.8-2.29Link
Cole G BradleyCOO2014-07-08Sell2,30022,891$27.0562.2-3.9622,891 (Direct)
Shak StevenEVP of R&D2014-07-01Sell7,000312,298$27189-3.78312,298 (Direct)
Shak StevenEVP of R&D2014-06-12Sell7,000312,298$26.73187.1-2.81312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-06-12Sell3,000271,289$26.178.3-0.46Link
Schorno Dean LCFO2014-06-10Sell4,00030,673$27.62110.5-5.9424,524 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2014-06-09Sell2,33722,891$27.2963.8-4.822,891 (Direct)
Popovits Kimberly JPresident and CEO2014-05-12Sell3,000270,579$26.5479.6-2.11Link
Schorno Dean LCFO2014-05-09Sell4,00029,963$25.09100.43.5523,814 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Shak StevenEVP of R&D2014-04-14Sell7,000311,588$26.25183.8-1.03311,588 (Direct)
Cole G BradleyCOO2014-04-08Sell3,00022,226$2781-3.7822,226 (Direct)
Shak StevenEVP of R&D2014-03-14Sell7,000311,588$28.36198.5-8.39311,588 (Direct)
Cole G BradleyCOO2014-03-10Sell3,00022,226$27.7683.3-6.4122,226 (Direct)
HIBBS KATHY LSVP & General Counsel2014-02-18Sell1,31215,787$27.8836.6-6.8115,787 (Direct)
Shak StevenEVP of R&D2014-02-14Sell7,000311,588$27.38191.7-5.11311,588 (Direct)
Cole G BradleyCOO2014-02-10Sell3,00024,789$2781-3.7824,789 (Direct)
Shak StevenEVP of R&D2014-01-15Sell7,000308,283$31.51220.6-17.55308,283 (Direct)
Popovits Kimberly JPresident and CEO2014-01-13Sell2,500261,190$3075-13.4Link
Cole G BradleyCOO2014-01-08Sell3,00018,369$28.1784.5-7.7718,369 (Direct)
Shak StevenEVP of R&D & CMO2013-12-17Sell14,000308,283$29.57414-12.14308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-12-12Sell2,5000$30.6876.7-15.32Link
Schorno Dean LCFO2013-12-09Sell3,00027,706$33.2599.8-21.8621,557 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-12-02Sell1,0006,149$34.9234.9-25.66,149 (Direct)
Popovits Kimberly JPresident and CEO2013-11-13Sell5,0000$34.58172.9-24.87Link
Schorno Dean LCFO2013-11-08Sell3,00027,585$33.36100.1-22.1221,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-11-06Sell2,86818,135$31.3890-17.2118,135 (Direct)
Shak StevenEVP of R&D & CMO2013-10-15Sell5,000308,283$29.67148.4-12.44308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-10-10Sell2,5000$3075-13.4Link
Cole G BradleyCOO2013-10-09Sell2,50018,135$29.9574.9-13.2618,135 (Direct)
Shak StevenEVP of R&D & CMO2013-09-18Sell5,000313,283$33.73168.7-22.98313,283 (Direct)
Popovits Kimberly JPresident and CEO2013-09-12Sell2,5000$34.3185.8-24.28Link
Cole G BradleyCOO2013-09-09Sell2,50018,135$32.5381.3-20.1418,135 (Direct)
Schorno Dean LCFO2013-09-06Sell4,00027,585$32.9131.6-21.0321,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-09-03Sell1,0006,149$31.4931.5-17.56,149 (Direct)
Shak StevenEVP of R&D & CMO2013-08-14Sell5,000318,283$32.98164.9-21.22318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-08-12Sell2,5000$33.0382.6-21.34Link
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-21.6321,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-21.6321,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-08-07Sell2,50019,135$33.6684.2-22.8219,135 (Direct)
Shak StevenEVP of R&D & CMO2013-07-23Sell5,000318,283$35.33176.7-26.46318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-07-12Sell5,0000$34.61173.1-24.93Link
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.2-23.1617,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.2-23.1617,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-07-08Sell2,50013,135$33.3383.3-22.0513,135 (Direct)
Shak StevenEVP of R&D & CMO2013-06-18Sell5,000323,283$33.52167.6-22.49323,283 (Direct)
Popovits Kimberly JPresident and CEO2013-06-12Sell5,0000$35.68178.4-27.19Link
Schorno Dean LCFO2013-06-10Sell4,00023,985$35.88143.5-27.5917,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER FELIXDirector, 10% Owner2013-06-05Buy381,43213,288,253$36.1613792.6-28.15
1,730,777 (See Footnote)
11,241,654 (See Footnotes(F7,F14,F15))
301,215 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-06-05Sell2,50013,135$36.4791.2-28.7613,135 (Direct)
BAKER FELIXDirector, 10% Owner2013-06-03Buy179,58312,906,821$36.716592.5-29.23
1,690,226 (See Footnote)
10,909,066 (See Footnotes(F7,F14,F15))
292,922 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-06-03Sell1,0006,149$36.436.4-28.636,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-29Buy121,26612,727,238$36.894473.5-29.57
1,671,081 (See Footnote)
10,752,532 (See Footnotes(F7,F14,F15))
289,018 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-05-24Buy79,41714,257,273$36.932932.9-29.65
1,651,301 (See Footnote)
10,646,920 (See Footnotes(F7,F17,F18))
286,384 (See Footnotes(F9,F17,F18))
1,658,061 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-22Sell1,0007,087$37.4837.5-30.687,087 (Direct)
Shak StevenEVP of R&D & CMO2013-05-21Sell5,000327,380$37.19186-30.14327,380 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-16Buy71,43912,526,555$36.452604-28.72
1,649,473 (See Footnote)
10,577,816 (See Footnotes(F7,F14,F15))
284,659 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-05-15Sell1,3376,149$35.8347.9-27.496,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-14Buy240,42614,093,759$34.348256.2-24.34
1,638,643 (See Footnote)
10,515,769 (See Footnotes(F7,F17,F18))
283,112 (See Footnotes(F9,F17,F18))
1,641,628 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-13Sell1,2507,087$34.4243-24.527,087 (Direct)
Popovits Kimberly JPresident and CEO2013-05-13Sell5,0000$34.7173.5-25.13Link
Schorno Dean LCFO2013-05-09Sell4,00023,241$36.02144.1-27.8717,092 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-05-08Sell2,50012,540$35.9990-27.8112,540 (Direct)
Popovits Kimberly JPresident and CEO2013-04-23Sell2,5000$3075-13.4Link
Cole G BradleyCOO2013-04-03Sell2,50012,540$27.7969.5-6.5112,540 (Direct)
Cole G BradleyCOO2013-03-06Sell2,50012,540$28.5771.4-9.0712,540 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-21Buy49,08512,211,834$27.781363.6-6.48
1,614,513 (See Footnote)
10,306,239 (See Footnotes(F7,F14,F15))
277,189 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
HIBBS KATHY LSVP & General Counsel2013-02-20Sell2,7167,087$28.1376.4-7.647,087 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-14Buy52,00012,162,749$28.481481-8.78
1,609,152 (See Footnote)
10,263,580 (See Footnotes(F7,F14,F15))
276,124 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
MYERS WOODROW A JRDirector2013-02-14Sell41,2502,891$28.41171.5-8.522,891 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-11Buy116,36012,110,749$28.153275.5-7.71
1,603,265 (See Footnote)
10,218,600 (See Footnotes(F7,F14,F15))
274,991 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-02-06Sell2,50014,085$28.0370.1-7.3114,085 (Direct)
LIVINGSTON RANDALL SDirector2013-01-28Sell2,0006,149$28.7757.5-9.76,149 (Direct)
Schorno Dean LCFO2013-01-09Sell2,62523,504$2873.5-7.2117,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-01-09Sell2,50014,085$27.8869.7-6.8114,085 (Direct)
Shak StevenEVP of R&D & CMO2012-12-18Sell5,000333,768$27.74138.7-6.34333,768 (Direct)
Popovits Kimberly JPresident and CEO2012-12-13Sell5,0000$27.79139-6.51Link
Schorno Dean LCFO2012-12-11Sell3,00023,504$2884-7.2117,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2012-11-26Sell2,0006,149$27.8455.7-6.686,149 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-21Buy229,30012,263,857$26.836152.1-3.17288 (Direct)
271,800 (See Footnote)
1,589,551 (See Footnotes(F5,F14,F15))
10,117,174 (See Footnotes(F7,F14,F15))
271,806 (See Footnotes(F9,F14,F15))
13,238 (See Footnote(F9,F14,F15))
COLELLA SAMUEL DDirector2012-11-20Sell30,61636,437$26.89823.3-3.3836,437 (Direct)
0 (Versant Venture Capital I, L.P.)
0 (Versant Side Fund I, L.P.)
0 (Versant Affiliates Fund I-A, L.P.)
0 (Versant Affiliates Fund I-B, L.P.)
Shak StevenEVP of R&D & CMO2012-11-20Sell5,000338,768$26.94134.7-3.56338,768 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-14Buy103,16713,526$27.322818.5-4.9288 (Direct)
13,238 (See Footnote)
Popovits Kimberly JPresident and CEO2012-11-14Sell5,0000$27.24136.2-4.63Link
BAKER FELIXDirector, 10% Owner2012-11-13Buy823,77213,526$27.8122909.1-6.58288 (Direct)
13,238 (See Footnote)
Schorno Dean LCFO2012-11-12Sell3,00023,504$2884-7.2117,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-11-08Sell2,50014,085$28.6271.6-9.2214,085 (Direct)
Popovits Kimberly JPresident and CEO2012-10-16Sell10,0000$33.08330.8-21.46Link
Shak StevenEVP of R&D & CMO2012-10-16Sell5,000343,768$35.25176.3-26.3343,768 (Direct)
Schorno Dean LCFO2012-10-12Sell3,00023,504$33.79101.4-23.1117,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
HIBBS KATHY LSVP & General Counsel2012-10-11Sell1,25011,367$33.7842.2-23.0911,367 (Direct)
Cole G BradleyCOO2012-10-09Sell2,50014,085$34.887-25.3414,085 (Direct)
Shak StevenEVP of R&D & CMO2012-09-18Sell5,000348,768$33.76168.8-23.05348,768 (Direct)
Popovits Kimberly JPresident and CEO2012-09-13Sell5,0000$31.69158.5-18.02Link
Cole G BradleyCOO2012-09-06Sell2,50014,085$35.0187.5-25.7914,085 (Direct)
MYERS WOODROW A JRDirector2012-08-21Sell16,5002,236$35.2580.8-26.192,236 (Direct)
Shak StevenEVP of R&D & CMO2012-08-20Sell5,000353,768$34.99175-25.75353,768 (Direct)
Popovits Kimberly JPresident and CEO2012-08-13Sell10,0000$34.72347.2-25.17Link
Cole G BradleyCOO2012-08-08Sell2,50014,085$30.4976.2-14.7914,085 (Direct)
LIVINGSTON RANDALL SDirector2012-07-26Sell2,0006,149$35.971.8-27.636,149 (Direct)
Shak StevenChief Medical Officer2012-07-24Sell5,000358,768$34.24171.2-24.12358,768 (Direct)
Popovits Kimberly JPresident and CEO2012-07-13Sell7,1000$34.76246.8-25.26Link
Scott Randal WCEO, InVitae Corporation*2012-07-11Sell30,0000$35.391061.7-26.59Link
Cole G BradleyCOO2012-07-05Sell2,50014,085$35.9589.9-27.7314,085 (Direct)
Shak StevenChief Medical Officer2012-06-25Sell5,000363,768$33.25166.3-21.86363,768 (Direct)
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-22.12Link
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-22.12Link
Scott Randal WCEO, InVitae Corporation*2012-06-12Sell30,0000$33.541006.2-22.54Link
Cole G BradleyCOO2012-06-06Sell2,50013,507$33.9784.9-23.5213,507 (Direct)
Shak StevenChief Medical Officer2012-05-24Sell5,000367,849$33.8169-23.14367,849 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-22Buy167,4061,488,539$32.265400.5-19.47
1,488,539 (See Footnote)
COLELLA SAMUEL DDirector2012-05-18Sell26,294664,113$33.03868.5-21.3426,891 (Direct)
582,174 (Versant Venture Capital I, L.P.)
11,210 (Versant Side Fund I, L.P.)
13,222 (Colella Family Partners, L.P.)
10,414 (Versant Affiliates Fund I-A, L.P.)
20,202 (Versant Affiliates Fund I-B, L.P.)
BAKER JULIANDirector, 10% Owner2012-05-16Buy376,0591,488,539$33.8812740.9-23.32
1,488,539 (See Footnote)
Popovits Kimberly JPresident and CEO2012-05-16Sell10,0000$34.23342.3-24.1Link
Schorno Dean LCFO2012-05-15Sell1,00023,504$33.6933.7-22.8917,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER JULIANDirector, 10% Owner2012-05-11Buy114,8881,488,539$29.963442-13.28
1,488,539 (See Footnote)
Scott Randal WCEO, InVitae Corporation*2012-05-11Sell30,0000$30.22906.6-14.03Link
Cole G BradleyCOO2012-05-09Sell2,50013,507$28.8772.2-10.0113,507 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-08Buy195,70113,238$28.455567.7-8.68
13,238 (See Footnote)
LIVINGSTON RANDALL SDirector2012-04-26Sell2,0006,149$28.2156.4-7.96,149 (Direct)
Shak StevenChief Medical Officer2012-04-24Sell5,000372,849$27.93139.7-6.98372,849 (Direct)
Popovits Kimberly JPresident and CEO2012-04-23Sell5,0000$27.79139-6.51Link
Schorno Dean LCFO2012-04-16Sell1,00024,504$27.9828-7.1518,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation*2012-04-11Sell20,0000$28.59571.8-9.13Link
Cole G BradleyCOO2012-04-04Sell2,50013,507$30.2875.7-14.213,507 (Direct)
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.4-13.63377,849 (Direct)
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.4-13.6Link
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.4-13.6Link
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.4-13.63377,849 (Direct)
Schorno Dean LCFO2012-03-15Sell1,00025,504$31.0831.1-16.4119,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation2012-03-13Sell30,0000$31.05931.5-16.33Link
Cole G BradleyCOO2012-03-08Sell2,50013,507$29.9474.9-13.2313,507 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-08Buy4,5081,484,977$30.11135.7-13.72
1,484,977 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-08Buy1,099227,840$30.1133.1-13.72
227,840 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-08Buy41,5848,255,421$30.111252.1-13.72
8,255,421 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-05Buy261,7618,213,837$29.817803.1-12.85
8,213,837 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-05Buy6,923226,741$29.81206.4-12.85
226,741 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-05Buy31,3321,480,469$29.81934-12.85
1,480,469 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-29Buy6,476219,818$29.06188.2-10.6
219,818 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-29Buy245,0317,952,076$29.067120.6-10.6
7,952,076 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-29Buy29,7561,449,137$29.06864.7-10.6
1,449,137 (Through Partnership)
Popovits Kimberly JPresident and CEO2012-02-24Sell10,0000$28.5285-8.84Link
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-23Buy114,5187,707,045$28.063213.4-7.41
7,707,045 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-23Buy3,022213,342$28.0684.8-7.41
213,342 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-23Buy13,3321,419,381$28.06374.1-7.41
1,419,381 (Through Partnership)
Shak StevenChief Medical Officer2012-02-23Sell5,000382,849$28.14140.7-7.68382,849 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-16Buy33,1851,406,049$29.34973.6-11.45
1,406,049 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-16Buy7,213210,320$29.37211.8-11.54
210,320 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-16Buy272,9097,592,527$29.378015.3-11.54
7,592,527 (Through Partnership)
Schorno Dean LCFO2012-02-15Sell75526,749$28.7621.7-9.6720,600 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2012-02-15Sell1,00026,504$28.7628.8-9.6720,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-10Buy417,9157,319,618$26.3611016.2-1.44
7,319,618 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-10Buy11,043203,107$26.36291.1-1.44
203,107 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-10Buy66,5831,372,864$26.361755.1-1.44
1,372,864 (Through Partnership)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.6-0.76Link
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.6-0.76Link
Cole G BradleyCOO2012-02-08Sell2,50014,450$26.4766.2-1.8514,450 (Direct)
LIVINGSTON RANDALL SDirector2012-01-26Sell2,0006,149$27.5155-5.566,149 (Direct)
Popovits Kimberly JPresident and CEO2012-01-25Sell5,0000$26.42132.1-1.67Link
Popovits Kimberly JPresident and CEO2012-01-24Sell5,0000$26.62133.1-2.4Link
Shak StevenChief Medical Officer2012-01-24Sell5,000382,778$26.74133.7-2.84382,778 (Direct)
Schorno Dean LCFO2012-01-17Sell1,00024,049$2828-7.2117,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-01-12Sell2,5007,750$27.5468.9-5.667,750 (Direct)
Scott Randal WExecutive Chairman2012-01-11Sell20,0000$27.46549.2-5.39Link
Shak StevenChief Medical Officer2011-12-22Sell5,000387,778$26.03130.2-0.19387,778 (Direct)
Scott Randal WExecutive Chairman2011-12-13Sell20,0000$27.29545.8-4.8Link
Cole G BradleyCOO2011-12-06Sell2,5007,750$28.5971.5-9.137,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-12-05Buy3,152192,064$28.1288.6-7.61
192,064 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-12-05Buy45,9771,306,281$27.661271.7-6.07
1,306,281 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-12-05Buy117,7516,901,703$28.123311.2-7.61
6,901,703 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-23Buy5,5311,260,304$25.91143.30.27
1,260,304 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-23Buy5,750188,912$25.94149.20.15
188,912 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-23Buy193,7396,783,952$25.915019.80.27
6,783,952 (Through Partnership)
Shak StevenChief Medical Officer2011-11-22Sell5,000392,778$26.07130.4-0.35392,778 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-16Buy64,5976,590,213$27.711790-6.24
6,590,213 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-16Buy2,550183,162$27.7170.7-6.24
183,162 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-16Buy4581,254,773$27.3512.5-5.01
1,254,773 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-14Buy10,106180,612$27.23275.2-4.59
180,612 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-14Buy249,3756,525,616$27.236790.5-4.59
6,525,616 (Through Partnership)
Scott Randal WExecutive Chairman2011-11-11Sell20,0000$27.24544.8-4.63Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-09Buy5421,254,315$26.7914.5-3.02
1,254,315 (Through Partnership)
Cole G BradleyCOO2011-11-08Sell2,5007,750$26.666.5-2.337,750 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-07Buy209,5126,276,241$25.945434.70.15
6,276,241 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-07Buy8,847170,506$25.94229.50.15
170,506 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-03Buy1201,253,773$24.482.96.13
1,253,773 (Through Partnership)
LIVINGSTON RANDALL SDirector2011-10-27Sell2,0006,149$22.0844.217.666,149 (Direct)
Shak StevenChief Medical Officer2011-10-24Sell5,000392,778$21.76108.819.39392,778 (Direct)
Scott Randal WExecutive Chairman2011-10-11Sell20,0000$22.83456.613.8Link
Cole G BradleyCOO2011-10-06Sell5,0007,750$22.31111.616.457,750 (Direct)
Scott Randal WExecutive Chairman2011-09-13Sell20,0000$20.81416.224.84Link
Cole G BradleyCOO2011-09-06Sell2,5007,750$22.0855.217.667,750 (Direct)
Shak StevenChief Medical Officer2011-08-24Sell5,000392,778$23.02115.112.86392,778 (Direct)
Scott Randal WExecutive Chairman2011-08-11Sell20,0000$24.44488.86.3Link
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.22.857,750 (Direct)
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.22.857,750 (Direct)
LIVINGSTON RANDALL SDirector2011-07-27Sell2,0006,149$26.4552.9-1.786,149 (Direct)
Shak StevenChief Medical Officer2011-07-25Sell5,000392,778$27.61138.1-5.9392,778 (Direct)
Scott Randal WExecutive Chairman2011-07-12Sell20,0001,503,444$27.36547.2-5.041,491,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Cole G BradleyCOO2011-07-06Sell5,0007,750$27.74138.7-6.347,750 (Direct)
Shak StevenChief Medical Officer2011-06-23Sell5,000392,778$27.12135.6-4.2392,778 (Direct)
Schorno Dean LCFO2011-06-15Sell1,00025,049$25.9125.90.2718,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-06-13Sell20,0001,523,444$25.69513.81.131,511,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-09Buy119194,415$26.193.1-0.8
194,415 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-06-09Buy4,388161,659$26.19114.9-0.8
161,659 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-09Buy203,6526,059,449$26.25335.7-0.84
6,059,449 (Through Partnership)
Cole G BradleyCOO2011-06-06Sell2,5007,750$26.1865.5-0.767,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-06-01Buy4,631157,271$27.34126.6-4.97
157,271 (Through Partnership)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-01Buy112194,296$27.353.1-5.01
194,296 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-01Buy181,6935,855,797$27.354969.3-5.01
5,855,797 (Through Partnership)
Shak StevenChief Medical Officer2011-05-25Sell5,000392,778$25.55127.81.68392,778 (Direct)
Schorno Dean LCFO2011-05-12Sell1,00026,049$26.4826.5-1.8919,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-05-11Sell20,0000$26.66533.2-2.55Link
Cole G BradleyCOO2011-05-09Sell2,5007,750$25.9364.80.197,750 (Direct)
LIVINGSTON RANDALL SDirector2011-04-27Sell2,0000$26.0452.1-0.23Link
Shak StevenChief Medical Officer2011-04-25Sell5,0000$25.38126.92.36Link
Popovits Kimberly JPresident and CEO2011-04-15Sell8,0000$25.49203.91.92Link
Schorno Dean LCFO2011-04-14Sell1,0000$25.3225.32.61Link
Scott Randal WExecutive Chairman2011-04-12Sell20,0000$25.96519.20.08Link
Cole G BradleyCOO2011-04-06Sell5,0000$26.91134.6-3.46Link
Shak StevenChief Medical Officer2011-03-24Sell5,0000$24.45122.36.26Link
Schorno Dean LCFO2011-03-15Sell1,0000$23.7923.89.21Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.36.96Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.36.96Link
Scott Randal WExecutive Chairman2011-03-11Sell20,0000$25.62512.41.41Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-10Buy70,8560$26.031844.4-0.19Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-08Buy9,6480$25.06241.83.67Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-08Buy349,5660$25.068760.13.67Link
Cole G BradleyCOO2011-03-08Sell2,5000$25.2363.12.97Link
COLELLA SAMUEL DDirector2011-03-03Sell34,3200$25.45873.42.08Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-02Buy160,3370$25.694119.11.13Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-02Buy4,4260$25.69113.71.13Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-02-25Buy158,3550$23.393703.911.07Link
14159 capital (GP), LLCDirector, 10% Owner2011-02-25Buy4,3700$23.39102.211.07Link
Shak StevenChief Medical Officer2011-02-24Sell5,0000$23.27116.411.65Link
Schorno Dean LCFO2011-02-15Sell1,0000$22.5122.515.42Link
Popovits Kimberly JPresident and CEO2011-02-15Sell8,0000$22.51180.115.42Link
Scott Randal WExecutive Chairman2011-02-11Sell20,0000$22.244417.03Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,000309,424$21.15169.222.84Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,0000$21.15169.222.84Link
Schorno Dean LCFO2011-01-13Sell1,27626,149$21.0626.923.36Link
Scott Randal WExecutive Chairman2011-01-11Sell20,0001,642,410$21.73434.619.56Link
Cole G BradleyCOO2011-01-06Sell5,0001,000$22.13110.717.4Link
Popovits Kimberly JPresident and CEO2010-12-16Sell8,000310,624$22.71181.714.4Link
Scott Randal WExecutive Chairman2010-12-13Sell20,0001,696,410$22.46449.215.67Link
Cole G BradleyCOO & CFO2010-12-13Sell2,5001,000$22.6456.614.75Link
Popovits Kimberly JPresident and CEO2010-11-16Sell8,000310,624$17.514048.46Link
Cole G BradleyCOO & CFO2010-11-11Sell2,5001,000$18.0445.144.01Link
Scott Randal WExecutive Chairman2010-11-11Sell20,0001,666,410$18.27365.442.2Link
Scott Randal WExecutive Chairman2010-10-12Sell20,0001,686,410$13.9527986.24Link
Popovits Kimberly JPresident and CEO2010-09-15Sell7,734310,624$15.1116.872.05Link
Scott Randal WExecutive Chairman2010-09-13Sell20,0001,706,410$14.87297.474.71Link
Cole G BradleyCOO & CFO2010-09-13Sell2,5001,000$15.0137.573.08Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-09Buy145134,196$14.812.175.42Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-09Buy5,2614,934,990$14.8177.975.42Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-02Buy65,4664,929,729$14.46946.679.67Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-02Buy1,807134,051$14.4626.179.67Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-30Buy3,415132,244$14.3749.180.79Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-30Buy123,7114,864,263$14.371777.780.79Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-23Buy150,4694,740,552$14.522184.878.93Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-23Buy4,153128,829$14.5260.378.93Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-18Buy530124,676$14.997.973.32Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-18Buy19,1874,590,083$14.99287.673.32Link
Popovits Kimberly JPresident and CEO2010-08-17Sell8,000288,116$15.07120.672.4Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-13Buy2,924124,146$14.8543.474.95Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-13Buy105,9104,570,896$14.851572.874.95Link
Cole G BradleyCOO & CFO2010-08-12Sell2,5001,000$1537.573.2Link
Scott Randal WExecutive Chairman2010-08-11Sell20,0001,726,410$14.71294.276.61Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-10Buy164,2424,464,986$14.612399.677.82Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-10Buy4,533121,222$14.6166.277.82Link
Baker JoffreChief Scientific Officer2010-08-09Sell4,629163,088$14.7568.376.14Link
Scott Randal WExecutive Chairman2010-07-13Sell20,0001,746,410$12.81256.2102.81Link
Baker JoffreChief Scientific Officer2010-07-07Sell4,629167,717$13.0560.499.08Link
Scott Randal WExecutive Chairman2010-06-11Sell20,0001,766,410$14.1528383.6Link
Baker JoffreChief Scientific Officer2010-06-10Sell4,629172,346$14.056584.91Link
Popovits Kimberly JPresident and CEO2010-05-17Sell8,000310,624$15.78126.264.64Link
Cole G BradleyCOO & CFO2010-05-12Sell2,5001,000$15.8739.763.71Link
Scott Randal WExecutive Chairman2010-05-11Sell20,0001,776,410$15.61312.266.43Link
Baker JoffreChief Scientific Officer2010-05-10Sell4,629176,975$15.5171.867.5Link
Scott Randal WExecutive Chairman2010-04-13Sell20,0001,796,410$16.87337.454Link
Cole G BradleyCOO & CFO2010-04-12Sell5,0001,000$16.984.553.73Link
Baker JoffreChief Scientific Officer2010-04-12Sell4,629181,604$16.8878.153.91Link
Popovits Kimberly JPresident and CEO2010-03-16Sell20,000288,116$19.4538933.57Link
Scott Randal WExecutive Chairman2010-03-11Sell20,0001,800,646$19.338634.61Link
Cole G BradleyCOO & CFO2010-03-11Sell2,5001,000$19.3948.533.99Link
COLELLA SAMUEL DDirector2010-03-10Sell106,70085,050$19.452075.333.57Link
Baker JoffreChief Scientific Officer2010-03-08Sell4,629150,120$19.8391.831.01Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-19Buy3,645116,689$17.0562.152.38Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-19Buy132,0704,300,744$17.052251.852.38Link
Scott Randal WExecutive Chairman2010-02-11Sell20,0001,830,646$17.23344.650.78Link
Cole G BradleyCOO & CFO2010-02-11Sell2,5001,000$17.5143.848.37Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-10Buy9,437113,044$17.01160.552.73Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-10Buy341,8544,168,674$17.015814.952.73Link
Baker JoffreChief Scientific Officer2010-02-09Sell4,629145,491$17.1479.351.58Link
Cole G BradleyCOO & CFO2010-01-12Sell5,0001,000$17.2586.350.61Link
Baker JoffreChief Scientific Officer2010-01-11Sell4,629150,120$17.4780.948.71Link
Shak StevenChief Medical Officer2009-12-21Sell5,000388,278$20.12100.629.13Link
Popovits Kimberly JPresident and CEO2009-12-15Sell5,000313,506$20.3910227.42Link
Cole G BradleyCOO & CFO2009-12-14Sell2,0001,000$20.4240.827.23Link
Scott Randal WExecutive Chairman2009-12-11Sell12,0001,880,646$20.24242.928.36Link
Baker JoffreChief Scientific Officer2009-12-08Sell4,629154,749$20.2693.828.23Link
Popovits Kimberly JPresident and CEO2009-11-17Sell20,000318,506$19.21384.235.24Link
Cole G BradleyCOO & CFO2009-11-12Sell6653,000$20.0413.329.64Link
Scott Randal WExecutive Chairman2009-11-11Sell12,0001,892,646$19.99239.929.96Link
Baker JoffreChief Scientific Officer2009-11-10Sell4,629159,378$2092.629.9Link
Shak StevenChief Medical Officer2009-10-20Sell5,000393,278$20.65103.325.81Link
Popovits Kimberly JPresident and CEO2009-10-15Sell5,000338,506$20.42102.127.23Link
Scott Randal WExecutive Chairman2009-10-13Sell12,0001,904,646$20.66247.925.75Link
Baker JoffreChief Scientific Officer2009-10-07Sell4,629164,007$21.179822.72Link
Shak StevenChief Medical Officer2009-09-22Sell5,000398,278$21.13105.722.95Link
Popovits Kimberly JPresident and CEO2009-09-15Sell5,000343,506$20.73103.725.33Link
Scott Randal WExecutive Chairman2009-09-11Sell12,0001,916,646$20.6724825.69Link
Baker JoffreChief Scientific Officer2009-09-04Sell4,629168,636$20.1293.129.13Link
Shak StevenChief Medical Officer2009-08-25Sell5,000403,278$20.77103.925.08Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-17Buy1,839103,607$19.9836.730.03Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-17Buy66,6303,826,820$19.981331.330.03Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-17Buy34194,184$19.980.730.03Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-17Buy11,6571,253,653$19.98232.930.03Link
Popovits Kimberly JPresident and CEO2009-08-17Sell5,000348,506$19.5397.733.03Link
Cole G BradleyCOO & CFO2009-08-13Sell5,0003,000$2010029.9Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-12Buy15,8771,241,996$19.49309.433.3Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-12Buy45194,150$19.50.933.23Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-12Buy90,7543,760,190$19.491768.833.3Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-12Buy2,508101,768$19.4948.933.3Link
Scott Randal WExecutive Chairman2009-08-11Sell12,0001,928,646$19.4223333.78Link
Baker JoffreChief Scientific Officer2009-08-10Sell4,629173,265$19.4890.233.37Link
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.162.27
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.162.27
Scott Randal WExecutive Chairman2009-06-11Sell6,0001,940,646$18.27109.642.2
Baker JoffreChief Scientific Officer2009-06-08Sell4,629182,523$17.6981.946.86
Shak StevenChief Medical Officer2009-05-26Sell5,000408,278$199536.74
14159 capital (GP), LLCDirector, 10% Owner2009-05-21Buy1,10899,260$17.9719.944.57
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-21Buy90194,161$17.971.644.57
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-21Buy39,7783,669,436$17.97714.844.57
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-21Buy25194,105$17.970.444.57
Popovits Kimberly JPresident and CEO2009-05-15Sell5,000353,506$20.12100.629.13
Scott Randal WExecutive Chairman2009-05-12Sell12,0001,946,646$19.46233.533.5
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-11Buy88194,080$19.551.732.89
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-11Buy312194,071$19.556.132.89
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-11Buy137,4663,629,658$19.552687.532.89
14159 capital (GP), LLCDirector, 10% Owner2009-05-11Buy3,82798,152$19.5574.832.89
Baker JoffreChief Scientific Officer2009-05-08Sell4,629187,152$19.7291.331.74
Scott Randal WExecutive Chairman2009-04-14Sell12,0001,958,646$25.47305.62
Baker JoffreChief Scientific Officer2009-04-01Sell4,629191,781$25.271172.81
Scott Randal WExecutive Chairman2009-03-11Sell12,0001,970,646$19.4232.833.92
Baker JoffreChief Scientific Officer2009-03-03Sell4,629196,410$19.1388.635.81
Cole G BradleyCOO & CFO2009-02-17Sell5,0003,000$21.52107.620.72
Baker JoffreChief Scientific Officer2009-02-12Sell4,62922,226$20.695.426.12
Baker JoffreChief Scientific Officer2009-02-12Sell4,629201,039$20.695.426.12
Scott Randal WExecutive Chairman, Director2009-02-11Sell12,0001,982,646$20.85250.224.6
Baker JoffreChief Scientific Officer2009-01-12Sell4,62926,855$19.4189.833.85
Shak StevenChief Medical Officer2008-12-22Sell100413,278$20.17228.81
Baker JoffreChief Scientific Officer2008-12-10Sell4,62931,484$19.2589.134.96
Baker JoffreChief Scientific Officer2008-12-10Sell4,629205,668$19.2589.134.96
Scott Randal WCEO, Director2008-12-09Sell12,0001,955,298$18.4220.841.2
Baker JoffreChief Scientific Officer2008-11-12Sell4,62936,113$19.879230.75
Baker JoffreChief Scientific Officer2008-11-12Sell4,629210,297$19.879230.75
Scott Randal WCEO, Director2008-11-11Sell12,0001,967,298$20.05240.629.58
Cole G BradleyEVP & CFO2008-11-10Sell10,0004,000$20.17201.728.81
Scott Randal WCEO, Director2008-10-14Sell12,0001,979,298$20.36244.327.6
Baker JoffreChief Scientific Officer2008-10-01Sell9,25840,742$22.51208.415.42
Shak StevenChief Medical Officer2008-09-24Sell5,000413,378$22.67113.414.6
Scott Randal WCEO, Director2008-09-16Sell12,0001,991,298$21.79261.519.23
Shak StevenChief Medical Officer2008-08-26Sell5,000418,378$22.93114.713.3
Baker JoffreChief Scientific Officer2008-08-26Sell4,629214,926$22.6910514.5
Cole G BradleyEVP & CFO2008-08-18Sell9,2984,000$23.67220.19.76
Popovits Kimberly JPresident and COO2008-08-15Sell25,000358,506$24.246067.18
Scott Randal WCEO, Director2008-08-12Sell12,0002,003,298$23.76285.19.34
Scott Randal WCEO, Director2008-07-15Sell12,0002,015,298$2125223.71
Baker JoffreChief Scientific Officer2008-07-01Sell4,629219,555$19.2689.234.89
Shak StevenChief Medical Officer2008-06-24Sell100423,378$20229.9
Scott Randal WCEO, Director2008-06-10Sell12,0002,027,298$19.9223930.42
Baker Brothers Life Sciences CDirector, 10% Owner2008-06-09Buy320,9833,492,192$19.916390.830.49
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-06-09Buy76,0151,226,119$19.911513.530.49
14159 capital (GP), LLCDirector, 10% Owner2008-06-09Buy10,29994,325$19.91205.130.49
Baker JoffreChief Scientific Officer2008-06-02Sell4,629228,813$17.9983.344.41
Scott Randal WCEO, Director2008-05-13Sell12,0002,039,298$18.7522538.56
Baker JoffreChief Scientific Officer2008-05-08Sell4,629233,442$19.2789.234.82
Scott Randal WCEO, Director2008-04-15Sell12,0002,051,298$17.22206.650.87
Scott Randal WCEO, Director2008-03-11Sell12,0002,063,298$18.84226.137.9
Baker JoffreChief Scientific Officer2008-03-05Sell4,629242,700$20.4894.826.86
Shak StevenChief Medical Officer2008-02-26Sell5,000423,478$20.23101.228.42
Cole G BradleyEVP & CFO2008-02-19Sell9,0008,298$22.58203.215.06
Scott Randal WCEO, Director2008-02-12Sell12,0002,075,298$23.01276.112.91
Baker JoffreChief Scientific Officer2008-02-11Sell4,629247,329$22.94106.213.25
Scott Randal WCEO, Director2008-01-15Sell12,0002,087,298$25.54306.51.72
Baker JoffreChief Scientific Officer2008-01-02Sell4,629251,958$22.66104.914.65
Baker JoffreChief Scientific Officer2007-12-03Sell4,6290$23.1106.912.47
Popovits Kimberly JPresident and COO2007-11-27Sell6,655383,506$22146.418.09
Scott Randal WCEO, Director2007-11-09Sell12,0002,111,299$23.07276.812.61
Baker JoffreChief Scientific Officer2007-11-08Sell4,629265,845$23.21107.411.93
Scott Randal WCEO2007-10-09Sell12,0002,123,299$20.16241.928.87
Baker JoffreChief Scientific Officer2007-10-01Sell4,629270,474$19.8491.830.95
Scott Randal WCEO2007-09-11Sell12,0002,135,299$19.69236.331.95
Scott Randal WCEO, Director2007-09-11Sell12,0002,135,299$19.7236.431.88
Baker JoffreChief Scientific Officer2007-09-10Sell4,629275,103$19.5790.632.75
Goldberg Michael DDirector2007-08-23Buy5,3505,350$18.76100.438.49
Scott Randal WCEO2007-08-15Sell12,0002,147,299$19.91238.930.49
Baker JoffreChief Scientific Officer2007-08-08Sell4,629279,732$19.449033.64
Scott Randal WCEO2007-07-18Sell12,0002,159,299$21.18254.222.66
Baker JoffreChief Scientific Officer2007-07-02Sell4,629284,361$19.018836.66
Scott Randal WCEO2007-06-19Sell12,0002,171,299$19.16229.935.59
Baker JoffreChief Scientific Officer2007-06-01Sell4,629288,990$17.5681.347.95
Baker Bros. Capital (GP), LLCDirector2007-05-30Buy545193,992$16.328.959.19
Baker Biotech Capital (GP), LLDirector2007-05-30Buy81,1811,150,104$16.321324.959.19
Baker Brothers Life Sciences CDirector2007-05-30Buy214,0993,171,209$16.323494.159.19
14159 capital (GP), LLCDirector2007-05-30Buy6,80784,026$16.32111.159.19
14159 capital (GP), LLCDirector2007-05-24Buy16,26177,219$16.59269.856.6
Baker Brothers Life Sciences CDirector2007-05-24Buy511,5532,957,110$16.598486.756.6
Baker Biotech Capital (GP), LLDirector2007-05-24Buy193,9661,068,923$16.593217.956.6
Baker Bros. Capital (GP), LLCDirector2007-05-24Buy1,303193,447$16.5921.656.6
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.967.61
14159 capital (GP), LLCDirector2007-05-21Buy22,49160,958$15.5348.667.61
14159 capital (GP), LLCDirector2007-05-21Buy160,958$15.5067.61
Baker Brothers Life Sciences CDirector2007-05-21Buy707,4582,445,557$15.510965.667.61
Baker Biotech Capital (GP), LLDirector2007-05-21Buy268,248874,957$15.54157.867.61
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.967.61
Scott Randal WCEO2007-05-08Sell12,0002,183,299$16.62199.456.32
Baker JoffreChief Scientific Officer2007-05-08Sell4,629293,619$16.3175.559.29
Scott Randal WCEO2007-04-10Sell12,0002,195,299$17.27207.250.43
Baker JoffreChief Scientific Officer2007-04-02Sell4,629298,248$17.1679.451.4
Baker / Tisch Capital (GP), LLDirector2007-03-09Buy3,181193,759$18.2858.142.12
Baker Bros. Capital (GP), LLCDirector2007-03-09Buy376190,341$18.286.942.12
Baker Biotech Capital (GP), LLDirector2007-03-09Buy62,325606,709$18.281139.342.12
Baker Brothers Life Sciences CDirector2007-03-09Buy168,5601,738,099$18.283081.342.12
14159 capital (GP), LLCDirector2007-03-09Buy5,37538,467$18.2898.342.12
Scott Randal WCEO2007-03-06Sell12,0002,207,299$18.35220.241.58
Baker Bros. Capital (GP), LLCDirector2007-03-02Buy119189,965$18.092.243.62
14159 capital (GP), LLCDirector2007-03-02Buy1,70733,092$18.0930.943.62
Baker / Tisch Capital (GP), LLDirector2007-03-02Buy1,072190,578$18.119.443.54
Baker Biotech Capital (GP), LLDirector2007-03-02Buy19,795544,384$18.09358.143.62
Baker Brothers Life Sciences CDirector2007-03-02Buy53,5331,569,539$18.09968.443.62
Baker JoffreChief Scientific Officer2007-03-01Sell4,629302,877$18.1884.242.9
MYERS WOODROW A JRDirector2007-02-21Buy2,00012,000$19.6339.332.35
Baker Brothers Life Sciences CDirector2007-02-16Buy25,4121,516,006$18.54471.140.13
Baker Biotech Capital (GP), LLDirector2007-02-16Buy9,396524,589$18.54174.240.13
Baker / Tisch Capital (GP), LLDirector2007-02-16Buy525189,506$18.549.740.13
14159 capital (GP), LLCDirector2007-02-16Buy81131,385$18.541540.13
Baker Bros. Capital (GP), LLCDirector2007-02-16Buy56189,846$18.54140.13
Baker Bros. Capital (GP), LLCDirector2007-02-14Buy579189,790$18.2510.642.36
Baker / Tisch Capital (GP), LLDirector2007-02-14Buy5,346188,981$18.2597.642.36
Baker Biotech Capital (GP), LLDirector2007-02-14Buy95,783515,193$18.25174842.36
14159 capital (GP), LLCDirector2007-02-14Buy8,25630,574$18.25150.742.36
Baker Brothers Life Sciences CDirector2007-02-14Buy259,0441,490,594$18.254727.642.36
Scott Randal WCEO2007-02-13Sell12,0002,219,299$18.12217.443.38
Baker JoffreChief Scientific Officer2007-02-08Sell4,629307,506$18.9787.836.95
Baker / Tisch Capital (GP), LLDirector2006-12-06Buy642183,635$21.5813.920.39
Baker Brothers Life Sciences CDirector2006-12-06Buy34,1731,231,550$21.58737.520.39
14159 capital (GP), LLCDirector2006-12-06Buy1,12022,318$21.5824.220.39
Baker Biotech Capital (GP), LLDirector2006-12-06Buy12,237419,410$21.58264.120.39
MYERS WOODROW A JRDirector2006-12-05Buy10,00010,000$21.97219.718.25
Baker / Tisch Capital (GP), LLDirector2006-12-05Buy9,096182,993$20.6187.426.12
Baker Biotech Capital (GP), LLDirector2006-12-05Buy173,441407,173$20.63572.926.12
14159 capital (GP), LLCDirector2006-12-05Buy15,88021,198$20.6327.126.12
Baker Brothers Life Sciences CDirector2006-12-05Buy484,3331,197,377$20.69977.326.12
14159 capital (GP), LLCDirector2006-09-08Buy5,3185,318$14.0574.784.91Link
Baker Biotech Capital (GP), LLDirector2006-09-08Buy75,246233,732$14.051057.284.91Link
Baker Brothers Life Sciences CDirector2006-09-08Buy237,236713,044$14.053333.284.91Link
Baker Biotech Capital III (GP)10% Owner2005-10-04Buy136,316252,529$121635.8116.5Link
Baker Biotech Capital II (GP),10% Owner2005-10-04Buy38,684181,478$12464.2116.5Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column) and "Shares Owned Following This (Direct & Indirect)" transactions (sixth column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported.

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