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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Dr. Randal W. Scott,PhDN/A1,185,1173.54%2012-07-10
Steven Shak,M.D.Chief Scientific Officer327,2070.98%2016-11-10
Joffre B. Baker,PhDN/A132,8460.4%2012-02-15
Dr. Fred E. Cohen,M.D.,D.Phil.N/A65,2380.19%2016-10-01
Kimberly J. PopovitsPresident and CEO59,6200.18%2016-11-03
G. Bradley ColeCOO35,4260.11%2016-11-08
Mr. James J. VaughnChief Commercial Officer26,079less than 0.1%2016-10-06
Mr. Frederic PlaN/A25,618less than 0.1%2016-02-15
Mr. Dean L. SchornoN/A24,524less than 0.1%2014-06-10
Brook H. ByersN/A23,951less than 0.1%2010-12-09

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
Leber LauraChief Communication Officer2016-11-21Sell7,06814,331$31.73224.27-6.8114,331 (Direct)
Shak StevenChief Scientific Officer2016-11-10Sell5,000327,207$31.71158.55-6.75327,207 (Direct)
Cole G BradleyCOO2016-11-08Sell5,00035,426$29.68148.4-0.3735,426 (Direct)
Popovits Kimberly JPresident and CEO
(Click for the stocks that their CEOs have bought)
2016-11-03Sell5,313289,594$28.88153.442.3959,620 (Direct)
200,851 (Held by the Popovits 2010 Trust)
12,298 (Held by UBS for Benefit of Kimberly Popovits)
16,825 (Held in trust for the benefit of Ms. Popovits' son, of which Ms. Popovits is trustee.)
Shak StevenChief Scientific Officer2016-10-11Sell5,000327,207$30.39151.95-2.7327,207 (Direct)
Cole G BradleyCOO2016-10-10Sell8,29035,426$30.59253.59-3.3335,426 (Direct)
Vaughn James JChief Commercial Officer2016-10-06Sell3,00026,079$29.6889.04-0.3726,079 (Direct)
Shak StevenChief Scientific Officer2016-09-13Sell5,000327,207$26.83134.1510.21327,207 (Direct)
Cole G BradleyCOO2016-09-06Sell4,00035,426$27.41109.647.8835,426 (Direct)
Shak StevenChief Scientific Officer2016-08-23Sell5,000327,207$27.24136.28.55327,207 (Direct)
BAKER FELIXDirector, 10% Owner2016-08-15Buy100,00011,841,478$27.0227029.44
318,623 (See footnote(,))
11,348,958 (See footnote(,,))
173,897 (See footnote(F1,))
Cole G BradleyCOO2016-08-11Sell5,00035,426$28.87144.352.4235,426 (Direct)
Vaughn James JChief Commercial Officer2016-08-08Sell3,00029,079$28.7486.222.8929,079 (Direct)
Shak StevenChief Scientific Officer2016-07-19Sell5,000327,207$27.42137.17.84327,207 (Direct)
Cole G BradleyCOO2016-07-06Sell5,00035,426$26.64133.21135,426 (Direct)
Shak StevenChief Scientific Officer2016-06-21Sell5,000327,207$25.77128.8514.75327,207 (Direct)
Cole G BradleyCOO2016-06-09Sell5,00035,426$26.62133.111.0835,426 (Direct)
Vaughn James JChief Commercial Officer2016-06-06Sell1,99732,079$2855.925.6132,079 (Direct)
Cole G BradleyCOO2016-05-16Sell5,00034,970$27.61387.1434,970 (Direct)
Febbo Phillip G.Chief Medical Officer2016-05-10Sell6,32415,013$27.2172.018.7115,013 (Direct)
Vaughn James JChief Commercial Officer2016-05-09Sell2,00031,255$28565.6131,255 (Direct)
Shak StevenChief Scientific Officer2016-05-04Sell10,000326,383$25.43254.316.28326,383 (Direct)
Vaughn James JChief Commercial Officer2016-02-09Sell324,076$280.085.6124,076 (Direct)
LIVINGSTON RANDALL SDirector2016-01-13Sell1,2506,149$32.1440.18-86,149 (Direct)
Cole G BradleyCOO2016-01-12Sell4,00027,428$31.69126.76-6.6927,428 (Direct)
Vaughn James JChief Commercial Officer2016-01-07Sell2,00024,076$33.6367.26-12.0724,076 (Direct)
Cole G BradleyCOO2015-12-08Sell4,00027,428$29.26117.041.0627,428 (Direct)
Leber LauraChief Communication Officer2015-12-07Sell4,20012,959$29.33123.190.8212,959 (Direct)
Vaughn James JChief Commercial Officer2015-12-07Sell2,00024,076$29.3358.660.8224,076 (Direct)
Cole G BradleyCOO2015-11-10Sell4,00030,326$26.03104.1213.630,326 (Direct)
Cole G BradleyCOO2015-09-09Sell9,66430,326$25.35244.9816.6530,326 (Direct)
Cole G BradleyCOO2015-07-07Sell4,00030,326$27.53110.127.4130,326 (Direct)
Cole G BradleyCOO2015-06-09Sell4,00030,326$26.24104.9612.6930,326 (Direct)
Cole G BradleyCOO2015-05-12Sell4,00029,658$27.54110.167.3729,658 (Direct)
Popovits Kimberly JPresident and CEO2015-04-13Sell3,000203,001$31.2893.84-5.47Link
Cole G BradleyCOO2015-04-07Sell4,00029,658$30.44121.76-2.8629,658 (Direct)
Popovits Kimberly JPresident and CEO2015-03-12Sell3,000204,101$31.9195.73-7.33Link
Cole G BradleyCOO2015-03-10Sell4,00029,658$31.84127.36-7.1329,658 (Direct)
Popovits Kimberly JPresident and CEO2015-02-12Sell3,000204,601$29.8689.58-0.97Link
Cole G BradleyCOO2015-02-10Sell4,00021,645$31.37125.48-5.7421,645 (Direct)
LIVINGSTON RANDALL SDirector2015-02-02Sell1,0006,149$31.9331.93-7.396,149 (Direct)
Popovits Kimberly JPresident and CEO2015-01-12Sell3,000204,601$33.46100.38-11.63Link
Popovits Kimberly JPresident and CEO2014-12-11Sell3,000204,601$32.9998.97-10.37Link
Cole G BradleyCOO2014-12-08Sell4,33621,645$32.52141.01-9.0721,645 (Direct)
Popovits Kimberly JPresident and CEO2014-11-12Sell4,300205,201$34.82149.73-15.08Link
Cole G BradleyCOO2014-11-10Sell4,00022,891$35.35141.4-16.3522,891 (Direct)
LIVINGSTON RANDALL SDirector2014-11-03Sell3,0006,149$36.24108.72-18.416,149 (Direct)
Popovits Kimberly JPresident and CEO2014-10-13Sell3,000205,201$30.7892.34-3.93Link
Cole G BradleyCOO2014-10-08Sell4,00022,891$28.77115.082.7822,891 (Direct)
Popovits Kimberly JPresident and CEO2014-09-11Sell3,000205,201$29.8289.46-0.84Link
Cole G BradleyCOO2014-09-08Sell4,70022,891$30.09141.42-1.7322,891 (Direct)
Shak StevenEVP of R&D2014-08-14Sell13,348312,298$27.36365.28.08312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-08-12Sell3,000205,201$26.0778.2113.43Link
Popovits Kimberly JPresident and CEO2014-07-14Sell3,000205,201$26.5979.7711.21Link
Cole G BradleyCOO2014-07-08Sell2,30022,891$27.0562.229.3222,891 (Direct)
Shak StevenEVP of R&D2014-07-01Sell7,000312,298$271899.52312,298 (Direct)
Shak StevenEVP of R&D2014-06-12Sell7,000312,298$26.73187.1110.62312,298 (Direct)
Popovits Kimberly JPresident and CEO2014-06-12Sell3,000271,289$26.178.313.3Link
Schorno Dean LCFO2014-06-10Sell4,00030,673$27.62110.487.0624,524 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2014-06-09Sell2,33722,891$27.2963.788.3522,891 (Direct)
Popovits Kimberly JPresident and CEO2014-05-12Sell3,000270,579$26.5479.6211.42Link
Schorno Dean LCFO2014-05-09Sell4,00029,963$25.09100.3617.8623,814 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Shak StevenEVP of R&D2014-04-14Sell7,000311,588$26.25183.7512.65311,588 (Direct)
Cole G BradleyCOO2014-04-08Sell3,00022,226$27819.5222,226 (Direct)
Shak StevenEVP of R&D2014-03-14Sell7,000311,588$28.36198.524.27311,588 (Direct)
Cole G BradleyCOO2014-03-10Sell3,00022,226$27.7683.286.5222,226 (Direct)
HIBBS KATHY LSVP & General Counsel2014-02-18Sell1,31215,787$27.8836.586.0615,787 (Direct)
Shak StevenEVP of R&D2014-02-14Sell7,000311,588$27.38191.668311,588 (Direct)
Cole G BradleyCOO2014-02-10Sell3,00024,789$27819.5224,789 (Direct)
Shak StevenEVP of R&D2014-01-15Sell7,000308,283$31.51220.57-6.16308,283 (Direct)
Popovits Kimberly JPresident and CEO2014-01-13Sell2,500261,190$3075-1.43Link
Cole G BradleyCOO2014-01-08Sell3,00018,369$28.1784.514.9718,369 (Direct)
Shak StevenEVP of R&D & CMO2013-12-17Sell14,000308,283$29.57413.980308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-12-12Sell2,5000$30.6876.7-3.62Link
Schorno Dean LCFO2013-12-09Sell3,00027,706$33.2599.75-11.0721,557 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-12-02Sell1,0006,149$34.9234.92-15.326,149 (Direct)
Popovits Kimberly JPresident and CEO2013-11-13Sell5,0000$34.58172.9-14.49Link
Schorno Dean LCFO2013-11-08Sell3,00027,585$33.36100.08-11.3621,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-11-06Sell2,86818,135$31.3890-5.7718,135 (Direct)
Shak StevenEVP of R&D & CMO2013-10-15Sell5,000308,283$29.67148.35-0.34308,283 (Direct)
Popovits Kimberly JPresident and CEO2013-10-10Sell2,5000$3075-1.43Link
Cole G BradleyCOO2013-10-09Sell2,50018,135$29.9574.88-1.2718,135 (Direct)
Shak StevenEVP of R&D & CMO2013-09-18Sell5,000313,283$33.73168.65-12.33313,283 (Direct)
Popovits Kimberly JPresident and CEO2013-09-12Sell2,5000$34.3185.78-13.82Link
Cole G BradleyCOO2013-09-09Sell2,50018,135$32.5381.33-9.118,135 (Direct)
Schorno Dean LCFO2013-09-06Sell4,00027,585$32.9131.6-10.1221,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2013-09-03Sell1,0006,149$31.4931.49-6.16,149 (Direct)
Shak StevenEVP of R&D & CMO2013-08-14Sell5,000318,283$32.98164.9-10.34318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-08-12Sell2,5000$33.0382.58-10.48Link
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-10.821,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-08-09Sell4,00027,585$33.15132.6-10.821,436 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-08-07Sell2,50019,135$33.6684.15-12.1519,135 (Direct)
Shak StevenEVP of R&D & CMO2013-07-23Sell5,000318,283$35.33176.65-16.3318,283 (Direct)
Popovits Kimberly JPresident and CEO2013-07-12Sell5,0000$34.61173.05-14.56Link
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.24-12.5417,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2013-07-09Sell4,00023,985$33.81135.24-12.5417,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-07-08Sell2,50013,135$33.3383.33-11.2813,135 (Direct)
Shak StevenEVP of R&D & CMO2013-06-18Sell5,000323,283$33.52167.6-11.78323,283 (Direct)
Popovits Kimberly JPresident and CEO2013-06-12Sell5,0000$35.68178.4-17.12Link
Schorno Dean LCFO2013-06-10Sell4,00023,985$35.88143.52-17.5917,836 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
BAKER FELIXDirector, 10% Owner2013-06-05Buy381,43213,288,253$36.1613792.58-18.22
1,730,777 (See Footnote)
11,241,654 (See Footnotes(F7,F14,F15))
301,215 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-06-05Sell2,50013,135$36.4791.18-18.9213,135 (Direct)
BAKER FELIXDirector, 10% Owner2013-06-03Buy179,58312,906,821$36.716592.49-19.45
1,690,226 (See Footnote)
10,909,066 (See Footnotes(F7,F14,F15))
292,922 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-06-03Sell1,0006,149$36.436.4-18.766,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-29Buy121,26612,727,238$36.894473.5-19.84
1,671,081 (See Footnote)
10,752,532 (See Footnotes(F7,F14,F15))
289,018 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
BAKER FELIXDirector, 10% Owner2013-05-24Buy79,41714,257,273$36.932932.87-19.93
1,651,301 (See Footnote)
10,646,920 (See Footnotes(F7,F17,F18))
286,384 (See Footnotes(F9,F17,F18))
1,658,061 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
HIBBS KATHY LSVP & General Counsel2013-05-22Sell1,0007,087$37.4837.48-21.17,087 (Direct)
Shak StevenEVP of R&D & CMO2013-05-21Sell5,000327,380$37.19185.95-20.49327,380 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-16Buy71,43912,526,555$36.452603.95-18.88
1,649,473 (See Footnote)
10,577,816 (See Footnotes(F7,F14,F15))
284,659 (See Footnotes(F9,F14,F15))
14,607 (See Footnote(F9,F14,F15))
LIVINGSTON RANDALL SDirector2013-05-15Sell1,3376,149$35.8347.9-17.476,149 (Direct)
BAKER FELIXDirector, 10% Owner2013-05-14Buy240,42614,093,759$34.348256.23-13.89
1,638,643 (See Footnote)
10,515,769 (See Footnotes(F7,F17,F18))
283,112 (See Footnotes(F9,F17,F18))
1,641,628 (See Footnotes(F5,F17,F18))
14,607 (See Footnote(F9,F17,F18))
Popovits Kimberly JPresident and CEO2013-05-13Sell5,0000$34.7173.5-14.78Link
HIBBS KATHY LSVP & General Counsel2013-05-13Sell1,2507,087$34.4243.03-14.097,087 (Direct)
Schorno Dean LCFO2013-05-09Sell4,00023,241$36.02144.08-17.9117,092 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2013-05-08Sell2,50012,540$35.9989.98-17.8412,540 (Direct)
Popovits Kimberly JPresident and CEO2013-04-23Sell2,5000$3075-1.43Link
Cole G BradleyCOO2013-04-03Sell2,50012,540$27.7969.486.4112,540 (Direct)
Cole G BradleyCOO2013-03-06Sell2,50012,540$28.5771.433.512,540 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-21Buy49,08512,211,834$27.781363.586.44
1,614,513 (See Footnote)
10,306,239 (See Footnotes(F7,F14,F15))
277,189 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
HIBBS KATHY LSVP & General Counsel2013-02-20Sell2,7167,087$28.1376.45.127,087 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-14Buy52,00012,162,749$28.481480.963.83
1,609,152 (See Footnote)
10,263,580 (See Footnotes(F7,F14,F15))
276,124 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
MYERS WOODROW A JRDirector2013-02-14Sell41,2502,891$28.41171.54.122,891 (Direct)
BAKER FELIXDirector, 10% Owner2013-02-11Buy116,36012,110,749$28.153275.535.04
1,603,265 (See Footnote)
10,218,600 (See Footnotes(F7,F14,F15))
274,991 (See Footnotes(F9,F14,F15))
13,893 (See Footnote(F9,F14,F15))
Cole G BradleyCOO2013-02-06Sell2,50014,085$28.0370.085.4914,085 (Direct)
LIVINGSTON RANDALL SDirector2013-01-28Sell2,0006,149$28.7757.542.786,149 (Direct)
Cole G BradleyCOO2013-01-09Sell2,50014,085$27.8869.76.0614,085 (Direct)
Schorno Dean LCFO2013-01-09Sell2,62523,504$2873.55.6117,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Shak StevenEVP of R&D & CMO2012-12-18Sell5,000333,768$27.74138.76.6333,768 (Direct)
Popovits Kimberly JPresident and CEO2012-12-13Sell5,0000$27.79138.956.41Link
Schorno Dean LCFO2012-12-11Sell3,00023,504$28845.6117,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
LIVINGSTON RANDALL SDirector2012-11-26Sell2,0006,149$27.8455.686.216,149 (Direct)
BAKER FELIXDirector, 10% Owner2012-11-21Buy229,30012,263,857$26.836152.1210.21288 (Direct)
271,800 (See Footnote)
1,589,551 (See Footnotes(F5,F14,F15))
10,117,174 (See Footnotes(F7,F14,F15))
271,806 (See Footnotes(F9,F14,F15))
13,238 (See Footnote(F9,F14,F15))
COLELLA SAMUEL DDirector2012-11-20Sell30,61636,437$26.89823.269.9736,437 (Direct)
0 (Versant Venture Capital I, L.P.)
0 (Versant Side Fund I, L.P.)
0 (Versant Affiliates Fund I-A, L.P.)
0 (Versant Affiliates Fund I-B, L.P.)
Shak StevenEVP of R&D & CMO2012-11-20Sell5,000338,768$26.94134.79.76338,768 (Direct)
Popovits Kimberly JPresident and CEO2012-11-14Sell5,0000$27.24136.28.55Link
BAKER FELIXDirector, 10% Owner2012-11-14Buy103,16713,526$27.322818.528.24288 (Direct)
13,238 (See Footnote)
BAKER FELIXDirector, 10% Owner2012-11-13Buy823,77213,526$27.8122909.16.33288 (Direct)
13,238 (See Footnote)
Schorno Dean LCFO2012-11-12Sell3,00023,504$28845.6117,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-11-08Sell2,50014,085$28.6271.553.3214,085 (Direct)
Popovits Kimberly JPresident and CEO2012-10-16Sell10,0000$33.08330.8-10.61Link
Shak StevenEVP of R&D & CMO2012-10-16Sell5,000343,768$35.25176.25-16.11343,768 (Direct)
Schorno Dean LCFO2012-10-12Sell3,00023,504$33.79101.37-12.4917,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
HIBBS KATHY LSVP & General Counsel2012-10-11Sell1,25011,367$33.7842.23-12.4611,367 (Direct)
Cole G BradleyCOO2012-10-09Sell2,50014,085$34.887-15.0314,085 (Direct)
Shak StevenEVP of R&D & CMO2012-09-18Sell5,000348,768$33.76168.8-12.41348,768 (Direct)
Popovits Kimberly JPresident and CEO2012-09-13Sell5,0000$31.69158.45-6.69Link
Cole G BradleyCOO2012-09-06Sell2,50014,085$35.0187.53-15.5414,085 (Direct)
MYERS WOODROW A JRDirector2012-08-21Sell16,5002,236$35.2580.8-15.992,236 (Direct)
Shak StevenEVP of R&D & CMO2012-08-20Sell5,000353,768$34.99174.95-15.49353,768 (Direct)
Popovits Kimberly JPresident and CEO2012-08-13Sell10,0000$34.72347.2-14.83Link
Cole G BradleyCOO2012-08-08Sell2,50014,085$30.4976.23-3.0214,085 (Direct)
LIVINGSTON RANDALL SDirector2012-07-26Sell2,0006,149$35.971.8-17.636,149 (Direct)
Shak StevenChief Medical Officer2012-07-24Sell5,000358,768$34.24171.2-13.64358,768 (Direct)
Popovits Kimberly JPresident and CEO2012-07-13Sell7,1000$34.76246.8-14.93Link
Scott Randal WCEO, InVitae Corporation*2012-07-11Sell30,0000$35.391061.7-16.45Link
Cole G BradleyCOO2012-07-05Sell2,50014,085$35.9589.88-17.7514,085 (Direct)
Shak StevenChief Medical Officer2012-06-25Sell5,000363,768$33.25166.25-11.07363,768 (Direct)
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-11.36Link
Popovits Kimberly JPresident and CEO2012-06-13Sell5,0000$33.36166.8-11.36Link
Scott Randal WCEO, InVitae Corporation*2012-06-12Sell30,0000$33.541006.2-11.84Link
Cole G BradleyCOO2012-06-06Sell2,50013,507$33.9784.93-12.9513,507 (Direct)
Shak StevenChief Medical Officer2012-05-24Sell5,000367,849$33.8169-12.51367,849 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-22Buy167,4061,488,539$32.265400.52-8.34
1,488,539 (See Footnote)
COLELLA SAMUEL DDirector2012-05-18Sell26,294664,113$33.03868.49-10.4826,891 (Direct)
582,174 (Versant Venture Capital I, L.P.)
11,210 (Versant Side Fund I, L.P.)
13,222 (Colella Family Partners, L.P.)
10,414 (Versant Affiliates Fund I-A, L.P.)
20,202 (Versant Affiliates Fund I-B, L.P.)
Popovits Kimberly JPresident and CEO2012-05-16Sell10,0000$34.23342.3-13.61Link
BAKER JULIANDirector, 10% Owner2012-05-16Buy376,0591,488,539$33.8812740.88-12.72
1,488,539 (See Footnote)
Schorno Dean LCFO2012-05-15Sell1,00023,504$33.6933.69-12.2317,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation*2012-05-11Sell30,0000$30.22906.6-2.15Link
BAKER JULIANDirector, 10% Owner2012-05-11Buy114,8881,488,539$29.963442.04-1.3
1,488,539 (See Footnote)
Cole G BradleyCOO2012-05-09Sell2,50013,507$28.8772.182.4213,507 (Direct)
BAKER JULIANDirector, 10% Owner2012-05-08Buy195,70113,238$28.455567.693.94
13,238 (See Footnote)
LIVINGSTON RANDALL SDirector2012-04-26Sell2,0006,149$28.2156.424.826,149 (Direct)
Shak StevenChief Medical Officer2012-04-24Sell5,000372,849$27.93139.655.87372,849 (Direct)
Popovits Kimberly JPresident and CEO2012-04-23Sell5,0000$27.79138.956.41Link
Schorno Dean LCFO2012-04-16Sell1,00024,504$27.9827.985.6818,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation*2012-04-11Sell20,0000$28.59571.83.43Link
Cole G BradleyCOO2012-04-04Sell2,50013,507$30.2875.7-2.3413,507 (Direct)
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.35-1.66Link
Popovits Kimberly JPresident and CEO2012-03-22Sell5,0000$30.07150.35-1.66Link
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.4-1.7377,849 (Direct)
Shak StevenChief Medical Officer2012-03-22Sell5,000377,849$30.08150.4-1.7377,849 (Direct)
Schorno Dean LCFO2012-03-15Sell1,00025,504$31.0831.08-4.8619,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WCEO, InVitae Corporation2012-03-13Sell30,0000$31.05931.5-4.77Link
Cole G BradleyCOO2012-03-08Sell2,50013,507$29.9474.85-1.2413,507 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-08Buy4,5081,484,977$30.11135.74-1.79
1,484,977 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-08Buy1,099227,840$30.1133.09-1.79
227,840 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-08Buy41,5848,255,421$30.111252.09-1.79
8,255,421 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-03-05Buy261,7618,213,837$29.817803.1-0.81
8,213,837 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-03-05Buy6,923226,741$29.81206.37-0.81
226,741 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-03-05Buy31,3321,480,469$29.81934.01-0.81
1,480,469 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-29Buy6,476219,818$29.06188.191.75
219,818 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-29Buy245,0317,952,076$29.067120.61.75
7,952,076 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-29Buy29,7561,449,137$29.06864.711.75
1,449,137 (Through Partnership)
Popovits Kimberly JPresident and CEO2012-02-24Sell10,0000$28.52853.75Link
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-23Buy114,5187,707,045$28.063213.385.38
7,707,045 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-23Buy3,022213,342$28.0684.85.38
213,342 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-23Buy13,3321,419,381$28.06374.15.38
1,419,381 (Through Partnership)
Shak StevenChief Medical Officer2012-02-23Sell5,000382,849$28.14140.75.08382,849 (Direct)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-16Buy33,1851,406,049$29.34973.650.78
1,406,049 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-16Buy7,213210,320$29.37211.850.68
210,320 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-16Buy272,9097,592,527$29.378015.340.68
7,592,527 (Through Partnership)
Schorno Dean LCFO2012-02-15Sell75526,749$28.7621.712.8220,600 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Schorno Dean LCFO2012-02-15Sell1,00026,504$28.7628.762.8220,355 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.612.95Link
Scott Randal WExecutive Chairman2012-02-10Sell20,0000$26.18523.612.95Link
Baker Brothers Life Sciences CDirector, 10% Owner2012-02-10Buy417,9157,319,618$26.3611016.2412.18
7,319,618 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2012-02-10Buy11,043203,107$26.36291.0912.18
203,107 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2012-02-10Buy66,5831,372,864$26.361755.1312.18
1,372,864 (Through Partnership)
Cole G BradleyCOO2012-02-08Sell2,50014,450$26.4766.1811.7114,450 (Direct)
LIVINGSTON RANDALL SDirector2012-01-26Sell2,0006,149$27.5155.027.496,149 (Direct)
Popovits Kimberly JPresident and CEO2012-01-25Sell5,0000$26.42132.111.92Link
Popovits Kimberly JPresident and CEO2012-01-24Sell5,0000$26.62133.111.08Link
Shak StevenChief Medical Officer2012-01-24Sell5,000382,778$26.74133.710.58382,778 (Direct)
Schorno Dean LCFO2012-01-17Sell1,00024,049$28285.6117,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Cole G BradleyCOO2012-01-12Sell2,5007,750$27.5468.857.377,750 (Direct)
Scott Randal WExecutive Chairman2012-01-11Sell20,0000$27.46549.27.68Link
Shak StevenChief Medical Officer2011-12-22Sell5,000387,778$26.03130.1513.6387,778 (Direct)
Scott Randal WExecutive Chairman2011-12-13Sell20,0000$27.29545.88.35Link
Cole G BradleyCOO2011-12-06Sell2,5007,750$28.5971.483.437,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-12-05Buy3,152192,064$28.1288.635.16
192,064 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-12-05Buy45,9771,306,281$27.661271.726.91
1,306,281 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-12-05Buy117,7516,901,703$28.123311.165.16
6,901,703 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-23Buy5,5311,260,304$25.91143.3114.13
1,260,304 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-23Buy5,750188,912$25.94149.1613.99
188,912 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-23Buy193,7396,783,952$25.915019.7814.13
6,783,952 (Through Partnership)
Shak StevenChief Medical Officer2011-11-22Sell5,000392,778$26.07130.3513.43392,778 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-16Buy64,5976,590,213$27.711789.986.71
6,590,213 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-16Buy2,550183,162$27.7170.666.71
183,162 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-16Buy4581,254,773$27.3512.538.12
1,254,773 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-14Buy10,106180,612$27.23275.198.59
180,612 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-14Buy249,3756,525,616$27.236790.488.59
6,525,616 (Through Partnership)
Scott Randal WExecutive Chairman2011-11-11Sell20,0000$27.24544.88.55Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-09Buy5421,254,315$26.7914.5210.38
1,254,315 (Through Partnership)
Cole G BradleyCOO2011-11-08Sell2,5007,750$26.666.511.177,750 (Direct)
Baker Brothers Life Sciences CDirector, 10% Owner2011-11-07Buy209,5126,276,241$25.945434.7413.99
6,276,241 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-11-07Buy8,847170,506$25.94229.4913.99
170,506 (Through Partnership)
Baker Biotech Capital (GP), LLDirector, 10% Owner2011-11-03Buy1201,253,773$24.482.9420.79
1,253,773 (Through Partnership)
LIVINGSTON RANDALL SDirector2011-10-27Sell2,0006,149$22.0844.1633.926,149 (Direct)
Shak StevenChief Medical Officer2011-10-24Sell5,000392,778$21.76108.835.89392,778 (Direct)
Scott Randal WExecutive Chairman2011-10-11Sell20,0000$22.83456.629.52Link
Cole G BradleyCOO2011-10-06Sell5,0007,750$22.31111.5532.547,750 (Direct)
Scott Randal WExecutive Chairman2011-09-13Sell20,0000$20.81416.242.1Link
Cole G BradleyCOO2011-09-06Sell2,5007,750$22.0855.233.927,750 (Direct)
Shak StevenChief Medical Officer2011-08-24Sell5,000392,778$23.02115.128.45392,778 (Direct)
Scott Randal WExecutive Chairman2011-08-11Sell20,0000$24.44488.820.99Link
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.1517.067,750 (Direct)
Cole G BradleyCOO2011-08-08Sell2,5007,750$25.2663.1517.067,750 (Direct)
LIVINGSTON RANDALL SDirector2011-07-27Sell2,0006,149$26.4552.911.86,149 (Direct)
Shak StevenChief Medical Officer2011-07-25Sell5,000392,778$27.61138.057.1392,778 (Direct)
Scott Randal WExecutive Chairman2011-07-12Sell20,0001,503,444$27.36547.28.081,491,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Cole G BradleyCOO2011-07-06Sell5,0007,750$27.74138.76.67,750 (Direct)
Shak StevenChief Medical Officer2011-06-23Sell5,000392,778$27.12135.69.03392,778 (Direct)
Schorno Dean LCFO2011-06-15Sell1,00025,049$25.9125.9114.1318,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-06-13Sell20,0001,523,444$25.69513.815.11,511,146 (Direct)
12,298 (By Morgan Stanley DW Inc. as Custodian for Randal W. Scott, IRA)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-09Buy119194,415$26.193.1212.91
194,415 (Through Partnership)
14159 capital (GP), LLCDirector, 10% Owner2011-06-09Buy4,388161,659$26.19114.9212.91
161,659 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-09Buy203,6526,059,449$26.25335.6812.86
6,059,449 (Through Partnership)
Cole G BradleyCOO2011-06-06Sell2,5007,750$26.1865.4512.957,750 (Direct)
14159 capital (GP), LLCDirector, 10% Owner2011-06-01Buy4,631157,271$27.34126.618.16
157,271 (Through Partnership)
Baker Bros. Capital (GP), LLCDirector, 10% Owner2011-06-01Buy112194,296$27.353.068.12
194,296 (Through Partnership)
Baker Brothers Life Sciences CDirector, 10% Owner2011-06-01Buy181,6935,855,797$27.354969.38.12
5,855,797 (Through Partnership)
Shak StevenChief Medical Officer2011-05-25Sell5,000392,778$25.55127.7515.73392,778 (Direct)
Schorno Dean LCFO2011-05-12Sell1,00026,049$26.4826.4811.6719,900 (Direct)
6,149 (By Charles Schwab & Co. as Custodian for Dean L. Schorno, IRA)
Scott Randal WExecutive Chairman2011-05-11Sell20,0000$26.66533.210.92Link
Cole G BradleyCOO2011-05-09Sell2,5007,750$25.9364.8314.047,750 (Direct)
LIVINGSTON RANDALL SDirector2011-04-27Sell2,0000$26.0452.0813.56Link
Shak StevenChief Medical Officer2011-04-25Sell5,0000$25.38126.916.51Link
Popovits Kimberly JPresident and CEO2011-04-15Sell8,0000$25.49203.9216.01Link
Schorno Dean LCFO2011-04-14Sell1,0000$25.3225.3216.79Link
Scott Randal WExecutive Chairman2011-04-12Sell20,0000$25.96519.213.91Link
Cole G BradleyCOO2011-04-06Sell5,0000$26.91134.559.88Link
Shak StevenChief Medical Officer2011-03-24Sell5,0000$24.45122.2520.94Link
Schorno Dean LCFO2011-03-15Sell1,0000$23.7923.7924.3Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.3221.74Link
Popovits Kimberly JPresident and CEO2011-03-15Sell8,0000$24.29194.3221.74Link
Scott Randal WExecutive Chairman2011-03-11Sell20,0000$25.62512.415.42Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-10Buy70,8560$26.031844.3813.6Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-08Buy9,6480$25.06241.7818Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-08Buy349,5660$25.068760.1218Link
Cole G BradleyCOO2011-03-08Sell2,5000$25.2363.0817.2Link
COLELLA SAMUEL DDirector2011-03-03Sell34,3200$25.45873.4416.19Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-03-02Buy160,3370$25.694119.0615.1Link
14159 capital (GP), LLCDirector, 10% Owner2011-03-02Buy4,4260$25.69113.715.1Link
Baker Brothers Life Sciences CDirector, 10% Owner2011-02-25Buy158,3550$23.393703.9226.42Link
14159 capital (GP), LLCDirector, 10% Owner2011-02-25Buy4,3700$23.39102.2126.42Link
Shak StevenChief Medical Officer2011-02-24Sell5,0000$23.27116.3527.07Link
Schorno Dean LCFO2011-02-15Sell1,0000$22.5122.5131.36Link
Popovits Kimberly JPresident and CEO2011-02-15Sell8,0000$22.51180.0831.36Link
Scott Randal WExecutive Chairman2011-02-11Sell20,0000$22.244433.2Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,0000$21.15169.239.81Link
Popovits Kimberly JPresident and CEO2011-01-18Sell8,000309,424$21.15169.239.81Link
Schorno Dean LCFO2011-01-13Sell1,27626,149$21.0626.8740.41Link
Scott Randal WExecutive Chairman2011-01-11Sell20,0001,642,410$21.73434.636.08Link
Cole G BradleyCOO2011-01-06Sell5,0001,000$22.13110.6533.62Link
Popovits Kimberly JPresident and CEO2010-12-16Sell8,000310,624$22.71181.6830.21Link
Scott Randal WExecutive Chairman2010-12-13Sell20,0001,696,410$22.46449.231.66Link
Cole G BradleyCOO & CFO2010-12-13Sell2,5001,000$22.6456.630.61Link
Popovits Kimberly JPresident and CEO2010-11-16Sell8,000310,624$17.514068.97Link
Cole G BradleyCOO & CFO2010-11-11Sell2,5001,000$18.0445.163.91Link
Scott Randal WExecutive Chairman2010-11-11Sell20,0001,666,410$18.27365.461.85Link
Scott Randal WExecutive Chairman2010-10-12Sell20,0001,686,410$13.95279111.97Link
Popovits Kimberly JPresident and CEO2010-09-15Sell7,734310,624$15.1116.7895.83Link
Scott Randal WExecutive Chairman2010-09-13Sell20,0001,706,410$14.87297.498.86Link
Cole G BradleyCOO & CFO2010-09-13Sell2,5001,000$15.0137.5397Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-09Buy145134,196$14.812.1599.66Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-09Buy5,2614,934,990$14.8177.9299.66Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-09-02Buy65,4664,929,729$14.46946.64104.5Link
14159 capital (GP), LLCDirector, 10% Owner2010-09-02Buy1,807134,051$14.4626.13104.5Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-30Buy3,415132,244$14.3749.07105.78Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-30Buy123,7114,864,263$14.371777.73105.78Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-23Buy150,4694,740,552$14.522184.81103.65Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-23Buy4,153128,829$14.5260.3103.65Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-18Buy530124,676$14.997.9497.26Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-18Buy19,1874,590,083$14.99287.6197.26Link
Popovits Kimberly JPresident and CEO2010-08-17Sell8,000288,116$15.07120.5696.22Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-13Buy2,924124,146$14.8543.4299.12Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-13Buy105,9104,570,896$14.851572.7699.12Link
Cole G BradleyCOO & CFO2010-08-12Sell2,5001,000$1537.597.13Link
Scott Randal WExecutive Chairman2010-08-11Sell20,0001,726,410$14.71294.2101.02Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-08-10Buy164,2424,464,986$14.612399.58102.4Link
14159 capital (GP), LLCDirector, 10% Owner2010-08-10Buy4,533121,222$14.6166.23102.4Link
Baker JoffreChief Scientific Officer2010-08-09Sell4,629163,088$14.7568.28100.47Link
Scott Randal WExecutive Chairman2010-07-13Sell20,0001,746,410$12.81256.2130.84Link
Baker JoffreChief Scientific Officer2010-07-07Sell4,629167,717$13.0560.41126.59Link
Scott Randal WExecutive Chairman2010-06-11Sell20,0001,766,410$14.15283108.98Link
Baker JoffreChief Scientific Officer2010-06-10Sell4,629172,346$14.0565.04110.46Link
Popovits Kimberly JPresident and CEO2010-05-17Sell8,000310,624$15.78126.2487.39Link
Cole G BradleyCOO & CFO2010-05-12Sell2,5001,000$15.8739.6886.33Link
Scott Randal WExecutive Chairman2010-05-11Sell20,0001,776,410$15.61312.289.43Link
Baker JoffreChief Scientific Officer2010-05-10Sell4,629176,975$15.5171.890.65Link
Scott Randal WExecutive Chairman2010-04-13Sell20,0001,796,410$16.87337.475.28Link
Cole G BradleyCOO & CFO2010-04-12Sell5,0001,000$16.984.574.97Link
Baker JoffreChief Scientific Officer2010-04-12Sell4,629181,604$16.8878.1475.18Link
Popovits Kimberly JPresident and CEO2010-03-16Sell20,000288,116$19.4538952.03Link
Scott Randal WExecutive Chairman2010-03-11Sell20,0001,800,646$19.338653.21Link
Cole G BradleyCOO & CFO2010-03-11Sell2,5001,000$19.3948.4852.5Link
COLELLA SAMUEL DDirector2010-03-10Sell106,70085,050$19.452075.3252.03Link
Baker JoffreChief Scientific Officer2010-03-08Sell4,629150,120$19.8391.7949.12Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-19Buy3,645116,689$17.0562.1573.43Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-19Buy132,0704,300,744$17.052251.7973.43Link
Scott Randal WExecutive Chairman2010-02-11Sell20,0001,830,646$17.23344.671.62Link
Cole G BradleyCOO & CFO2010-02-11Sell2,5001,000$17.5143.7868.87Link
14159 capital (GP), LLCDirector, 10% Owner2010-02-10Buy9,437113,044$17.01160.5273.84Link
Baker Brothers Life Sciences CDirector, 10% Owner2010-02-10Buy341,8544,168,674$17.015814.9473.84Link
Baker JoffreChief Scientific Officer2010-02-09Sell4,629145,491$17.1479.3472.52Link
Cole G BradleyCOO & CFO2010-01-12Sell5,0001,000$17.2586.2571.42Link
Baker JoffreChief Scientific Officer2010-01-11Sell4,629150,120$17.4780.8769.26Link
Shak StevenChief Medical Officer2009-12-21Sell5,000388,278$20.12100.646.97Link
Popovits Kimberly JPresident and CEO2009-12-15Sell5,000313,506$20.39101.9545.02Link
Cole G BradleyCOO & CFO2009-12-14Sell2,0001,000$20.4240.8444.81Link
Scott Randal WExecutive Chairman2009-12-11Sell12,0001,880,646$20.24242.8846.1Link
Baker JoffreChief Scientific Officer2009-12-08Sell4,629154,749$20.2693.7845.95Link
Popovits Kimberly JPresident and CEO2009-11-17Sell20,000318,506$19.21384.253.93Link
Cole G BradleyCOO & CFO2009-11-12Sell6653,000$20.0413.3347.55Link
Scott Randal WExecutive Chairman2009-11-11Sell12,0001,892,646$19.99239.8847.92Link
Baker JoffreChief Scientific Officer2009-11-10Sell4,629159,378$2092.5847.85Link
Shak StevenChief Medical Officer2009-10-20Sell5,000393,278$20.65103.2543.2Link
Popovits Kimberly JPresident and CEO2009-10-15Sell5,000338,506$20.42102.144.81Link
Scott Randal WExecutive Chairman2009-10-13Sell12,0001,904,646$20.66247.9243.13Link
Baker JoffreChief Scientific Officer2009-10-07Sell4,629164,007$21.179839.68Link
Shak StevenChief Medical Officer2009-09-22Sell5,000398,278$21.13105.6539.94Link
Popovits Kimberly JPresident and CEO2009-09-15Sell5,000343,506$20.73103.6542.64Link
Scott Randal WExecutive Chairman2009-09-11Sell12,0001,916,646$20.67248.0443.06Link
Baker JoffreChief Scientific Officer2009-09-04Sell4,629168,636$20.1293.1446.97Link
Shak StevenChief Medical Officer2009-08-25Sell5,000403,278$20.77103.8542.37Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-17Buy1,839103,607$19.9836.7448Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-17Buy66,6303,826,820$19.981331.2748Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-17Buy34194,184$19.980.6848Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-17Buy11,6571,253,653$19.98232.9148Link
Popovits Kimberly JPresident and CEO2009-08-17Sell5,000348,506$19.5397.6551.41Link
Cole G BradleyCOO & CFO2009-08-13Sell5,0003,000$2010047.85Link
Baker Biotech Capital (GP), LLDirector, 10% Owner2009-08-12Buy15,8771,241,996$19.49309.4451.72Link
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-08-12Buy45194,150$19.50.8851.64Link
Baker Brothers Life Sciences CDirector, 10% Owner2009-08-12Buy90,7543,760,190$19.491768.851.72Link
14159 capital (GP), LLCDirector, 10% Owner2009-08-12Buy2,508101,768$19.4948.8851.72Link
Scott Randal WExecutive Chairman2009-08-11Sell12,0001,928,646$19.42233.0452.27Link
Baker JoffreChief Scientific Officer2009-08-10Sell4,629173,265$19.4890.1751.8Link
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.1184.7
Baker JoffreChief Scientific Officer2009-07-08Sell4,629177,894$16.0174.1184.7
Scott Randal WExecutive Chairman2009-06-11Sell6,0001,940,646$18.27109.6261.85
Baker JoffreChief Scientific Officer2009-06-08Sell4,629182,523$17.6981.8967.16
Shak StevenChief Medical Officer2009-05-26Sell5,000408,278$199555.63
14159 capital (GP), LLCDirector, 10% Owner2009-05-21Buy1,10899,260$17.9719.9164.55
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-21Buy39,7783,669,436$17.97714.8164.55
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-21Buy25194,105$17.970.4564.55
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-21Buy90194,161$17.971.6264.55
Popovits Kimberly JPresident and CEO2009-05-15Sell5,000353,506$20.12100.646.97
Scott Randal WExecutive Chairman2009-05-12Sell12,0001,946,646$19.46233.5251.95
Baker Bros. Capital (GP), LLCDirector, 10% Owner2009-05-11Buy88194,080$19.551.7251.25
Baker Brothers Life Sciences CDirector, 10% Owner2009-05-11Buy137,4663,629,658$19.552687.4651.25
14159 capital (GP), LLCDirector, 10% Owner2009-05-11Buy3,82798,152$19.5574.8251.25
Baker / Tisch Capital (GP), LLDirector, 10% Owner2009-05-11Buy312194,071$19.556.151.25
Baker JoffreChief Scientific Officer2009-05-08Sell4,629187,152$19.7291.2849.95
Scott Randal WExecutive Chairman2009-04-14Sell12,0001,958,646$25.47305.6416.1
Baker JoffreChief Scientific Officer2009-04-01Sell4,629191,781$25.27116.9717.02
Scott Randal WExecutive Chairman2009-03-11Sell12,0001,970,646$19.4232.852.42
Baker JoffreChief Scientific Officer2009-03-03Sell4,629196,410$19.1388.5554.57
Cole G BradleyCOO & CFO2009-02-17Sell5,0003,000$21.52107.637.41
Baker JoffreChief Scientific Officer2009-02-12Sell4,62922,226$20.695.3643.54
Baker JoffreChief Scientific Officer2009-02-12Sell4,629201,039$20.695.3643.54
Scott Randal WExecutive Chairman, Director2009-02-11Sell12,0001,982,646$20.85250.241.82
Baker JoffreChief Scientific Officer2009-01-12Sell4,62926,855$19.4189.8552.34
Shak StevenChief Medical Officer2008-12-22Sell100413,278$20.172.0246.6
Baker JoffreChief Scientific Officer2008-12-10Sell4,62931,484$19.2589.1153.61
Baker JoffreChief Scientific Officer2008-12-10Sell4,629205,668$19.2589.1153.61
Scott Randal WCEO, Director2008-12-09Sell12,0001,955,298$18.4220.860.71
Baker JoffreChief Scientific Officer2008-11-12Sell4,62936,113$19.8791.9848.82
Baker JoffreChief Scientific Officer2008-11-12Sell4,629210,297$19.8791.9848.82
Scott Randal WCEO, Director2008-11-11Sell12,0001,967,298$20.05240.647.48
Cole G BradleyEVP & CFO2008-11-10Sell10,0004,000$20.17201.746.6
Scott Randal WCEO, Director2008-10-14Sell12,0001,979,298$20.36244.3245.24
Baker JoffreChief Scientific Officer2008-10-01Sell9,25840,742$22.51208.431.36
Shak StevenChief Medical Officer2008-09-24Sell5,000413,378$22.67113.3530.44
Scott Randal WCEO, Director2008-09-16Sell12,0001,991,298$21.79261.4835.7
Shak StevenChief Medical Officer2008-08-26Sell5,000418,378$22.93114.6528.96
Baker JoffreChief Scientific Officer2008-08-26Sell4,629214,926$22.69105.0330.32
Cole G BradleyEVP & CFO2008-08-18Sell9,2984,000$23.67220.0824.93
Popovits Kimberly JPresident and COO2008-08-15Sell25,000358,506$24.2460621.99
Scott Randal WCEO, Director2008-08-12Sell12,0002,003,298$23.76285.1224.45
Scott Randal WCEO, Director2008-07-15Sell12,0002,015,298$2125240.81
Baker JoffreChief Scientific Officer2008-07-01Sell4,629219,555$19.2689.1553.53
Shak StevenChief Medical Officer2008-06-24Sell100423,378$20247.85
Scott Randal WCEO, Director2008-06-10Sell12,0002,027,298$19.92239.0448.44
Baker Brothers Life Sciences CDirector, 10% Owner2008-06-09Buy320,9833,492,192$19.916390.7748.52
Baker Biotech Capital (GP), LLDirector, 10% Owner2008-06-09Buy76,0151,226,119$19.911513.4648.52
14159 capital (GP), LLCDirector, 10% Owner2008-06-09Buy10,29994,325$19.91205.0548.52
Baker JoffreChief Scientific Officer2008-06-02Sell4,629228,813$17.9983.2864.37
Scott Randal WCEO, Director2008-05-13Sell12,0002,039,298$18.7522557.71
Baker JoffreChief Scientific Officer2008-05-08Sell4,629233,442$19.2789.253.45
Scott Randal WCEO, Director2008-04-15Sell12,0002,051,298$17.22206.6471.72
Scott Randal WCEO, Director2008-03-11Sell12,0002,063,298$18.84226.0856.95
Baker JoffreChief Scientific Officer2008-03-05Sell4,629242,700$20.4894.844.38
Shak StevenChief Medical Officer2008-02-26Sell5,000423,478$20.23101.1546.17
Cole G BradleyEVP & CFO2008-02-19Sell9,0008,298$22.58203.2230.96
Scott Randal WCEO, Director2008-02-12Sell12,0002,075,298$23.01276.1228.51
Baker JoffreChief Scientific Officer2008-02-11Sell4,629247,329$22.94106.1928.9
Scott Randal WCEO, Director2008-01-15Sell12,0002,087,298$25.54306.4815.78
Baker JoffreChief Scientific Officer2008-01-02Sell4,629251,958$22.66104.8930.49
Baker JoffreChief Scientific Officer2007-12-03Sell4,6290$23.1106.9328.01
Popovits Kimberly JPresident and COO2007-11-27Sell6,655383,506$22146.4134.41
Scott Randal WCEO, Director2007-11-09Sell12,0002,111,299$23.07276.8428.18
Baker JoffreChief Scientific Officer2007-11-08Sell4,629265,845$23.21107.4427.4
Scott Randal WCEO2007-10-09Sell12,0002,123,299$20.16241.9246.68
Baker JoffreChief Scientific Officer2007-10-01Sell4,629270,474$19.8491.8449.04
Scott Randal WCEO2007-09-11Sell12,0002,135,299$19.69236.2850.18
Scott Randal WCEO, Director2007-09-11Sell12,0002,135,299$19.7236.450.1
Baker JoffreChief Scientific Officer2007-09-10Sell4,629275,103$19.5790.5951.1
Goldberg Michael DDirector2007-08-23Buy5,3505,350$18.76100.3757.62
Scott Randal WCEO2007-08-15Sell12,0002,147,299$19.91238.9248.52
Baker JoffreChief Scientific Officer2007-08-08Sell4,629279,732$19.4489.9952.11
Scott Randal WCEO2007-07-18Sell12,0002,159,299$21.18254.1639.61
Baker JoffreChief Scientific Officer2007-07-02Sell4,629284,361$19.018855.55
Scott Randal WCEO2007-06-19Sell12,0002,171,299$19.16229.9254.33
Baker JoffreChief Scientific Officer2007-06-01Sell4,629288,990$17.5681.2968.39
Baker Bros. Capital (GP), LLCDirector2007-05-30Buy545193,992$16.328.8981.19
Baker Biotech Capital (GP), LLDirector2007-05-30Buy81,1811,150,104$16.321324.8781.19
Baker Brothers Life Sciences CDirector2007-05-30Buy214,0993,171,209$16.323494.181.19
14159 capital (GP), LLCDirector2007-05-30Buy6,80784,026$16.32111.0981.19
14159 capital (GP), LLCDirector2007-05-24Buy16,26177,219$16.59269.7778.24
Baker Brothers Life Sciences CDirector2007-05-24Buy511,5532,957,110$16.598486.6678.24
Baker Biotech Capital (GP), LLDirector2007-05-24Buy193,9661,068,923$16.593217.978.24
Baker Bros. Capital (GP), LLCDirector2007-05-24Buy1,303193,447$16.5921.6278.24
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.9590.77
14159 capital (GP), LLCDirector2007-05-21Buy22,49160,958$15.5348.6190.77
14159 capital (GP), LLCDirector2007-05-21Buy160,958$15.50.0290.77
Baker Brothers Life Sciences CDirector2007-05-21Buy707,4582,445,557$15.510965.690.77
Baker Biotech Capital (GP), LLDirector2007-05-21Buy268,248874,957$15.54157.8490.77
Baker Bros. Capital (GP), LLCDirector2007-05-21Buy1,803192,144$15.527.9590.77
Scott Randal WCEO2007-05-08Sell12,0002,183,299$16.62199.4477.92
Baker JoffreChief Scientific Officer2007-05-08Sell4,629293,619$16.3175.581.3
Scott Randal WCEO2007-04-10Sell12,0002,195,299$17.27207.2471.22
Baker JoffreChief Scientific Officer2007-04-02Sell4,629298,248$17.1679.4372.32
Baker Bros. Capital (GP), LLCDirector2007-03-09Buy376190,341$18.286.8761.76
Baker Biotech Capital (GP), LLDirector2007-03-09Buy62,325606,709$18.281139.361.76
Baker Brothers Life Sciences CDirector2007-03-09Buy168,5601,738,099$18.283081.2861.76
14159 capital (GP), LLCDirector2007-03-09Buy5,37538,467$18.2898.2661.76
Baker / Tisch Capital (GP), LLDirector2007-03-09Buy3,181193,759$18.2858.1561.76
Scott Randal WCEO2007-03-06Sell12,0002,207,299$18.35220.261.14
Baker Bros. Capital (GP), LLCDirector2007-03-02Buy119189,965$18.092.1563.46
14159 capital (GP), LLCDirector2007-03-02Buy1,70733,092$18.0930.8863.46
Baker Biotech Capital (GP), LLDirector2007-03-02Buy19,795544,384$18.09358.0963.46
Baker Brothers Life Sciences CDirector2007-03-02Buy53,5331,569,539$18.09968.4163.46
Baker / Tisch Capital (GP), LLDirector2007-03-02Buy1,072190,578$18.119.463.37
Baker JoffreChief Scientific Officer2007-03-01Sell4,629302,877$18.1884.1662.65
MYERS WOODROW A JRDirector2007-02-21Buy2,00012,000$19.6339.2650.64
Baker Brothers Life Sciences CDirector2007-02-16Buy25,4121,516,006$18.54471.1459.49
Baker Biotech Capital (GP), LLDirector2007-02-16Buy9,396524,589$18.54174.259.49
14159 capital (GP), LLCDirector2007-02-16Buy81131,385$18.5415.0459.49
Baker Bros. Capital (GP), LLCDirector2007-02-16Buy56189,846$18.541.0459.49
Baker / Tisch Capital (GP), LLDirector2007-02-16Buy525189,506$18.549.7359.49
Baker Bros. Capital (GP), LLCDirector2007-02-14Buy579189,790$18.2510.5762.03
Baker Biotech Capital (GP), LLDirector2007-02-14Buy95,783515,193$18.251748.0462.03
14159 capital (GP), LLCDirector2007-02-14Buy8,25630,574$18.25150.6762.03
Baker Brothers Life Sciences CDirector2007-02-14Buy259,0441,490,594$18.254727.5562.03
Baker / Tisch Capital (GP), LLDirector2007-02-14Buy5,346188,981$18.2597.5662.03
Scott Randal WCEO2007-02-13Sell12,0002,219,299$18.12217.4463.19
Baker JoffreChief Scientific Officer2007-02-08Sell4,629307,506$18.9787.8155.88
Baker Brothers Life Sciences CDirector2006-12-06Buy34,1731,231,550$21.58737.4537.03
14159 capital (GP), LLCDirector2006-12-06Buy1,12022,318$21.5824.1737.03
Baker Biotech Capital (GP), LLDirector2006-12-06Buy12,237419,410$21.58264.0737.03
Baker / Tisch Capital (GP), LLDirector2006-12-06Buy642183,635$21.5813.8537.03
MYERS WOODROW A JRDirector2006-12-05Buy10,00010,000$21.97219.734.59
Baker Biotech Capital (GP), LLDirector2006-12-05Buy173,441407,173$20.63572.8843.54
14159 capital (GP), LLCDirector2006-12-05Buy15,88021,198$20.6327.1343.54
Baker Brothers Life Sciences CDirector2006-12-05Buy484,3331,197,377$20.69977.2643.54
Baker / Tisch Capital (GP), LLDirector2006-12-05Buy9,096182,993$20.6187.3843.54
14159 capital (GP), LLCDirector2006-09-08Buy5,3185,318$14.0574.72110.46Link
Baker Biotech Capital (GP), LLDirector2006-09-08Buy75,246233,732$14.051057.21110.46Link
Baker Brothers Life Sciences CDirector2006-09-08Buy237,236713,044$14.053333.17110.46Link
Baker Biotech Capital III (GP)10% Owner2005-10-04Buy136,316252,529$121635.79146.42Link
Baker Biotech Capital II (GP),10% Owner2005-10-04Buy38,684181,478$12464.21146.42Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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