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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Robert L. PriddyN/A324,3720.27%2007-10-01
Dr. Harry F. Hixson, JrN/A233,7940.2%2015-02-10
Dr. Ronald M. Lindsay, PhDN/A209,8040.18%2016-02-10
Dr. Dirk Van Den Boom, PhDPresident & CEO175,6180.15%2016-06-10
Dr. Harry Stylli,PhDN/A142,5110.12%2009-03-13
Dr. Kenneth F. Buechler, PhDN/A120,0380.1%2016-01-04
Paul W. HawranN/A115,8880.1%2009-03-13
Mr. David PendarvisN/A112,969less than 0.1%2016-01-04
Ms. Carolyn D. BeaverSVP & CFO107,567less than 0.1%2016-06-10
Dr. Ernst-Gunter Afting,PhD,M.D.N/A97,499less than 0.1%2008-12-16

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
BEAVER CAROLYNSVP & CFO
(Click for the stocks that their CFOs have bought)
2016-06-10Buy30,000157,567$1.133-21.82107,567 (Direct)
50,000 (by Spouse)
BEAVER CAROLYNSVP & CFO
(Click for the stocks that their CFOs have bought)
2016-06-09Buy10,000124,067$1.111-21.82104,067 (Direct)
20,000 (by Spouse)
LINTON JEFFREY DSr VP, GC & Secretary2016-06-09Buy5,00042,853$1.15.5-21.8242,853 (Direct)
VAN DEN BOOM DIRKPresident & CEO
(Click for the stocks that their CEOs have bought)
2016-06-08Buy40,000173,044$1.0943.6-21.1173,044 (Direct)
GROSU DANIEL S MDSVP & CMO2016-05-11Buy30,00051,424$1.1133.3-22.5251,424 (Direct)
VAN DEN BOOM DIRKPresident & CEO2016-05-06Buy30,000133,044$1.1333.9-23.89133,044 (Direct)
LINTON JEFFREY DSr VP, GC & Secretary2016-05-06Buy10,00037,853$1.1511.5-25.2237,853 (Direct)
BEAVER CAROLYNSVP & CFO2016-05-06Buy30,000114,067$1.1434.2-24.5694,067 (Direct)
20,000 (By spouse)
Camber Capital Management LLC10% Owner2016-01-04Buy665,43551,429,565$1.621078-46.91
16,854,565 (See Footnotes(F1,F2))
17,250,000 (See Footnotes(F1,F3))
17,325,000 (See Footnotes(F1,F4,F5))
Camber Capital Management LLC10% Owner2015-12-16Buy468,00049,918,695$1.3608.4-33.85
16,619,565 (See Footnotes(F1,F2))
16,639,565 (See Footnotes(F1,F3))
16,659,565 (See Footnotes(F1,F4,F5))
Camber Capital Management LLC10% Owner2015-12-15Buy468,00049,918,695$1.3608.4-33.85
16,619,565 (See Footnotes(F1,F2))
16,639,565 (See Footnotes(F1,F3,F4))
16,659,565 (See Footnotes(F1,F4,F5))
Camber Capital Management LLC10% Owner2015-12-10Buy791,56547,404,565$1.31029.03-33.85
15,275,000 (See Footnotes(F1,F2))
15,938,000 (See Footnotes(F1,F3))
16,191,565 (See Footnotes(F1,F4,F5))
Camber Capital Management LLC10% Owner2015-10-08Buy1,650,090118,556,342$1.963234.18-56.12
14,250,000 (See Footnotes(F1,F2))
14,489,892 (See Footnotes(F1,F3))
14,511,644 (See Footnotes(F1,F4))
14,675,044 (See Footnotes(F1,F5))
14,837,762 (See Footnotes(F1,F6))
15,000,000 (See Footnotes(F1,F7))
15,392,000 (See Footnotes(F1,F8))
15,400,000 (See Footnotes(F1,F9,F10))
WELCH WILLIAM JCEO2015-03-10Buy10,00052,627$3.6536.5-76.4452,627 (Direct)
BEAVER CAROLYNCFO2015-03-09Buy10,00048,543$3.636-76.1138,543 (Direct)
10,000 (by Spouse)
LINTON JEFFREY DSr VP & General Counsel2015-03-06Buy10,00010,000$3.6436.4-76.3710,000 (Direct)
LAI GOLDMAN MYLADirector2012-11-29Buy4,0004,000$4.5918.36-81.264,000 (Direct)
FAZIO JOHN ADirector2012-11-26Buy2,00026,019$4.458.9-80.6726,019 (Direct)
SLACIK CHARLES PDirector2012-08-08Buy5,00010,000$3.2416.2-73.4610,000 (Direct)
FAZIO JOHN ADirector2012-08-07Buy2,00024,019$3.336.66-74.1724,019 (Direct)
BEAVER CAROLYNVP and Chief Accounting Office2012-08-03Buy10,00010,000$3.1331.3-72.52
10,000 (by Spouse)
MAIER PAUL VCFO2012-08-01Buy10,00063,111$2.8628.6-69.9353,111 (Direct)
10,000 (by Trust)
LINDSAY RONALD MExec VP, R&D2012-08-01Buy100,000167,243$2.99299-71.24167,243 (Direct)
HIXSON HARRY F JRCEO2012-08-01Buy50,000150,161$2.92146-70.55100,161 (Direct)
50,000 (by Trust)
FAZIO JOHN ADirector2012-06-06Buy80022,019$3.652.92-76.4422,019 (Direct)
FAZIO JOHN ADirector2012-05-18Buy1,00021,219$4.354.35-80.2321,219 (Direct)
FAZIO JOHN ADirector2012-05-17Buy1,00020,219$4.974.97-82.720,219 (Direct)
BOMBARD ALLANChief Medical Officer2011-12-12Buy7,00026,892$3.9327.51-78.1226,892 (Direct)
FAZIO JOHN ADirector2011-12-06Buy1,50019,219$46-78.519,219 (Direct)
FAZIO JOHN ADirector2011-11-21Buy1,50017,719$46-78.517,719 (Direct)
MYRES LARRYVP, Operations2011-07-15Sell1,0004,257$7.597.59-88.674,257 (Direct)
MYRES LARRYVP, Operations2011-06-15Sell1,0005,257$7.497.49-88.525,257 (Direct)
MYRES LARRYVP, Operations2011-05-16Sell1,0066,257$8.138.18-89.426,257 (Direct)
NEUMANN CLARKEVP & General Counsel2011-05-09Sell6,11119,945$848.89-89.2517,945 (Direct)
2,000 (by Spouse)
NEUMANN CLARKEVP & General Counsel2011-05-02Sell5000$7.073.54-87.84Link
MYRES LARRYVP, Operations2011-04-15Sell1,0060$7.077.11-87.84Link
NEUMANN CLARKEVP & General Counsel2011-04-07Sell5,0000$735-87.71Link
NEUMANN CLARKEVP & General Counsel2011-04-01Sell1,0000$6.386.38-86.52Link
FAZIO JOHN ADirector2011-03-17Buy1,0000$5.845.84-85.27Link
MYRES LARRYVP, Operations2011-03-15Sell1,0000$5.645.64-84.75Link
BUECHLER KENNETH FDirector2011-03-10Buy17,8500$5.5999.78-84.62Link
LINDSAY RONALD MExec VP, R&D2011-03-10Buy20,0000$5.54110.8-84.48Link
NEUMANN CLARKEVP & General Counsel2011-03-01Sell1,0000$6.126.12-85.95Link
MYRES LARRYVP, Operations2011-02-15Sell1,0000$6.736.73-87.22Link
NEUMANN CLARKEVP & General Counsel2011-02-01Sell1,00022,445$6.926.92-87.5720,445 (Direct)
2,000 (by Spouse)
MYRES LARRYVP, Operations2011-01-18Sell1,00010,269$7.447.44-88.44Link
NEUMANN CLARKEVP & General Counsel2011-01-03Sell1,00023,445$8.068.06-89.33Link
FAZIO JOHN ADirector2010-08-25Buy1,0009,253$5.55.5-84.36Link
BOMBARD ALLANChief Medical Officer2010-08-13Buy4,34513,638$5.7424.94-85.02Link
FAZIO JOHN ADirector2010-08-10Buy1,0008,253$5.85.8-85.17Link
Ridgeback Capital Investments10% Owner2009-04-30Sell4,561,1716,019,291$4.3419795.48-80.18
OWINGS STEVEVP Ops, Prenatal Diagnostics2009-03-24Sell22,5980$16.19365.86-94.69
HAWRAN PAUL WCFO2009-03-13Buy2,000115,888$13.4626.92-93.61
Stylli HarryPresident and CEO2009-03-13Buy2,000142,511$13.4326.86-93.6
FAZIO JOHN ADirector2009-03-06Buy5007,253$12.756.38-93.25
HAWRAN PAUL WCFO2009-03-04Buy5,000113,888$13.4567.25-93.61
Stylli HarryPresident and CEO, Director2009-02-13Buy10,000140,511$16.5165-94.79
FAZIO JOHN ADirector2009-02-13Buy5006,753$16.958.48-94.93
Schmidt KarstenVP, Business Development2008-12-24Sell5,00021,665$19.8899.4-95.67
AFTING ERNST-GUNTERDirector2008-12-09Sell6,30037,499$16.52104.08-94.79
Ridgeback Capital Investments10% Owner2008-09-10Buy325,00010,580,462$19.476327.75-95.58
Stylli HarryPresident and CEO, Director2008-08-11Buy10,000129,342$18.92189.2-95.45
Ridgeback Capital Investments10% Owner2008-08-08Buy210,00010,255,462$18.993987.9-95.47
Ridgeback Capital Investments10% Owner2008-08-07Buy245,00010,045,462$19.974892.65-95.69
Ridgeback Capital Investments10% Owner2008-08-06Buy136,5999,800,462$19.982729.25-95.7
Ridgeback Capital Investments10% Owner2008-08-05Buy100,0009,663,863$20.412041-95.79
Ridgeback Capital Investments10% Owner2008-08-04Buy250,0009,563,863$20.915227.5-95.89
Ridgeback Capital Investments10% Owner2008-07-31Buy100,0009,313,863$20.952095-95.89
Ridgeback Capital Investments10% Owner2008-07-29Buy313,8639,213,863$21.556763.75-96.01
Ridgeback Capital Investments10% Owner2008-07-17Buy1,400,0008,900,000$21.0129414-95.91
Ridgeback Capital Investments10% Owner2008-07-01Buy380,0007,500,000$15.966064.8-94.61
Ridgeback Capital Investments10% Owner2008-06-30Buy395,0007,120,000$15.966304.2-94.61
Ridgeback Capital Investments10% Owner2008-06-27Buy350,0006,725,000$15.265341-94.36
Ridgeback Capital Investments10% Owner2008-06-26Buy480,0006,375,000$15.237310.4-94.35
RA CAPITAL MANAGEMENT, LLC10% Owner2008-06-25Buy19,2695,872,966$16.14311-94.67
RA CAPITAL MANAGEMENT, LLC10% Owner2008-06-25Buy341,5675,853,697$15.55294.29-94.45
RA CAPITAL MANAGEMENT, LLC10% Owner2008-06-25Buy33,4175,512,130$15.01501.59-94.27
RA CAPITAL MANAGEMENT, LLC10% Owner2008-06-25Buy25,7485,478,714$14.47372.57-94.06
LEHMAN BROTHERS HOLDINGS INC10% Owner2008-06-11Sell1,750,0004,545,532$12.0921157.5-92.89
RA CAPITAL MANAGEMENT, LLC10% Owner2008-06-10Buy183,6005,452,966$12.182236.25-92.94
RA CAPITAL MANAGEMENT, LLC10% Owner2008-06-09Buy208,1195,056,415$12.922688.9-93.34
RA CAPITAL MANAGEMENT, LLC10% Owner2008-06-09Buy59,8304,848,296$12.6753.86-93.17
RA CAPITAL MANAGEMENT, LLC10% Owner2008-06-09Buy126,7004,788,466$12.091531.8-92.89
RA CAPITAL MANAGEMENT, LLC10% Owner2008-06-09Buy15,4004,661,766$12184.8-92.83
Stylli HarryPresident and CEO2006-08-11Buy31,94654,700$1.8458.78-53.26Link
AFTING ERNST-GUNTERDirector2006-08-09Buy14,73334,999$1.7625.93-51.14Link
Stylli HarryPresident and CEO2006-08-08Buy21,75422,754$1.7437.85-50.57Link
CANTOR CHARLES RChief Scientific Officer2004-09-08Buy13,332135,725$2.7636.8-68.84Link
MACDONALD RICHARDEVP, Bioinformatics and IT2003-07-30Sell1,0402,988$9.69.98-91.04Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

"Shares" change (fifth column), "Shares Owned Following This (Direct & Indirect)" transactions (sixth column), and "Trade Price ($)" (seventh column) are split adjusted. The "Share Ownership Details" (last column) displayed data is as of reported (also split adjusted).

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