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Top Direct Holders

HolderPositionShares% of Shares
Outstanding
Report Date
Stephen A. Hill,B.M.President and CEO195,0000.58%2014-10-17
Alan A. MussoSVP, CFO & Treasurer57,7990.17%2014-10-17
Steven M. TolerN/A46,0000.14%2014-10-17
Mr. Patrick C. RockN/A45,0000.13%2014-10-17
Mauri K. HodgesVP, Fin. & Admin., CFO, Treas.41,2590.12%2014-12-11
Jones Elaine VN/A27,500less than 0.1%2007-11-29
Dr. Merouane Bencherif,M.D.SVP, Preclinical Research15,938less than 0.1%2012-05-18
Desouza Errol BN/A15,333less than 0.1%2014-12-11
Mr. John P. RichardDirector15,333less than 0.1%2014-12-11
Mr. Mark B. SkaletskyDirector11,332less than 0.1%2010-11-16

Insider Charts

Insider Transactions

Insider Position Date Buy/Sell Shares Shares Owned Following This (Direct & Indirect) Trade Price ($) Cost ($1000) Price Change
Since Trade (%)
Share Ownership Details
BARRETT M JAMES10% Owner2013-12-05Sell16,0004,563,512$5.3785.9-54.38
0 (See Note 3)
4,563,512 (See Note 4)
BARRIS PETER J10% Owner2013-12-05Sell1,0004,563,512$5.135.1-52.24
0 (See Note 2)
4,563,512 (See Note 3)
SANDELL SCOTT D10% Owner2013-12-05Sell1,0004,563,512$5.135.1-52.24
0 (See Note 2)
4,563,512 (See Note 3)
SANDELL SCOTT D10% Owner2013-11-21Sell5,3334,564,512$5.1627.5-52.52
1,000 (See Note 2)
4,563,512 (See Note 3)
BARRIS PETER J10% Owner2013-11-21Sell5,3334,564,512$5.1627.5-52.52
1,000 (See Note 2)
4,563,512 (See Note 3)
BARRETT M JAMES10% Owner2013-11-21Sell5,3334,564,512$5.1627.5-52.52
1,000 (See Note 2)
4,563,512 (See Note 3)
BROWN JULIA RDirector2013-05-10Buy6,0006,000$5.0930.5-51.87
6,000 (By Julia R. Brown Trust)
HILL STEPHEN APresident and CEO
(Click for the stocks that their CEOs have bought)
2013-03-11Buy20,00020,000$4.4388.6-44.720,000 (Direct)
HILL STEPHEN APresident and CEO2013-03-11Buy20,00020,000$4.4388.6-44.720,000 (Direct)
BVF PARTNERS L P/IL10% Owner2012-11-16Buy1,290,212349,482$4.065238.3-39.66
349,482 (See Explanation of Responses)
BVF PARTNERS L P/IL10% Owner2012-11-16Buy595,000349,482$42380-38.75
349,482 (See Explanation of Responses)
BVF PARTNERS L P/IL10% Owner2012-11-08Buy72,4291,052,258$4.03291.9-39.21
1,052,258 (See Explanation of Responses)
BVF PARTNERS L P/IL10% Owner2012-11-02Buy139,7001,026,058$4.05565.8-39.51
1,026,058 (See Explanation of Responses)
Richard John PDirector2012-06-08Buy7,50012,833$4.1631.2-41.115,333 (Direct)
7,500 (By trust)
Richard John PDirector2011-07-01Sell2,5005,333$21.0252.6-88.345,333 (Direct)
Musso Alan ASVP, CFO & Treasurer2011-06-07Sell30,8752,799$21.8673.1-88.762,799 (Direct)
BROWN JULIA RDirector2011-05-13Sell9,1000$23.38212.8-89.52Link
BURRILL STEVENDirector2011-05-12Sell52,0000$23.941244.9-89.77
0 (By Burrill & Company LLC)
0 (By Burrill Biotechnology Capital Fund L.P.)
BURRILL STEVENDirector2011-05-11Sell52,0000$23.941244.9-89.77
0 (By Burrill & Company LLC)
0 (By Burrill Biotechnology Capital Fund L.P.)
Richard John PDirector2011-04-01Sell2,5000$26.666.5-90.79Link

Only the transactions in Open Market or Private Sale at the market prices are included. Other transactions such as Conversion of derivative security or Exercise of Options are not included. Insiders are only limited to Officers and/or Directors of the company.

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