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GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength

vs
industry
vs
history
Cash to Debt 113.978
CCXI's Cash to Debt is ranked lower than
51% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: 10000.00 vs. CCXI: 113.978 )
CCXI' s 10-Year Cash to Debt Range
Min: 7.51   Max: 125.84
Current: 113.98

7.51
125.84
Equity to Asset 0.902
CCXI's Equity to Asset is ranked higher than
92% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: 0.54 vs. CCXI: 0.902 )
CCXI' s 10-Year Equity to Asset Range
Min: 0.75   Max: 0.9
Current: 0.9

0.75
0.9
Z-Score: 33.99
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth

vs
industry
vs
history
Operating margin (%) -731.30
CCXI's Operating margin (%) is ranked lower than
73% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: -52.55 vs. CCXI: -731.30 )
CCXI' s 10-Year Operating margin (%) Range
Min: -731.3   Max: 31.6
Current: -731.3

-731.3
31.6
Net-margin (%) -736.1
CCXI's Net-margin (%) is ranked lower than
74% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: -55.70 vs. CCXI: -736.1 )
CCXI' s 10-Year Net-margin (%) Range
Min: -736.1   Max: 31.4
Current: -736.1

-736.1
31.4
ROE (%) -36.2
CCXI's ROE (%) is ranked higher than
51% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: -16.60 vs. CCXI: -36.2 )
CCXI' s 10-Year ROE (%) Range
Min: -36.2   Max: 20.2
Current: -36.2

-36.2
20.2
ROA (%) -32.6
CCXI's ROA (%) is ranked lower than
57% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: -14.40 vs. CCXI: -32.6 )
CCXI' s 10-Year ROA (%) Range
Min: -32.6   Max: 15.1
Current: -32.6

-32.6
15.1
» CCXI's 10-Y Financials

Financials


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow

» Details

Guru Trades

CCXI Guru Trades in

CCXI Guru Trades in

CCXI Guru Trades in

Q1 2013

CCXI Guru Trades in Q1 2013

Tom Russo 162 sh (New)
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» Details

Insider Trades

Latest Guru Trades with CCXI



No Insider Trades Found!

Ratios

vs
industry
vs
history
P/B 4.53
CCXI's P/B is ranked higher than
57% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: 3.80 vs. CCXI: 4.53 )
CCXI' s 10-Year P/B Range
Min: 2.46   Max: 4.96
Current: 4.53

2.46
4.96
P/S 80.06
CCXI's P/S is ranked lower than
58% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: 6.90 vs. CCXI: 80.06 )
CCXI' s 10-Year P/S Range
Min: 68.59   Max: 576.33
Current: 80.06

68.59
576.33
EV-to-EBIT -12.34
CCXI's EV-to-EBIT is ranked higher than
72% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: 14.61 vs. CCXI: -12.34 )
CCXI' s 10-Year EV-to-EBIT Range
Min: 46.6   Max: 97
Current: -12.34

46.6
97

Valuation & Return

vs
industry
vs
history
Price/Net Cash 5.6
CCXI's Price/Net Cash is ranked higher than
65% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: 8.80 vs. CCXI: 5.6 )
CCXI' s 10-Year Price/Net Cash Range
Min: 4.3   Max: 4.3
Current: 5.6

Price/Net Current Asset Value 141.3
CCXI's Price/Net Current Asset Value is ranked lower than
61% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: 32.60 vs. CCXI: 141.3 )
CCXI' s 10-Year Price/Net Current Asset Value Range
Min: 109.4   Max: 109.4
Current: 141.3

Price/Tangible Book 4.5
CCXI's Price/Tangible Book is ranked lower than
93% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: 4.70 vs. CCXI: 4.5 )
CCXI' s 10-Year Price/Tangible Book Range
Min: 3.5   Max: 3.5
Current: 4.5

Price/Median PS Value 0.8
CCXI's Price/Median PS Value is ranked lower than
93% of the 349 Companies
in the Global Biotechnology industry.

( Industry Median: 0.90 vs. CCXI: 0.8 )
CCXI' s 10-Year Price/Median PS Value Range
Min: 0.6   Max: 0.6
Current: 0.8

Business Description

Chemocentryx, Inc. is incorporated in the state of Delaware. The company commenced operations in 1997. It is a biopharmaceutical company focused on discovering, developing and commercializing orally-administered therapeutics to treat autoimmune diseases, inflammatory disorders and cancer. The company's approach has been to target the chemokine system, a network of molecules including chemokine ligands and their associated receptors, as well as related chemo-attractant receptors, all of which are known to drive inflammation. It currently has five drug candidates in clinical development, and expects to advance one additional drug candidate into clinical development in 2012. Two of these drug candidates are wholly owned and are being developed independently by the company while four are subject to its collaboration agreement with Glaxo Group Limited, or GSK, an affiliate of GlaxoSmithKline. Under this agreement, GSK has exercised its option to obtain an exclusive license to further develop and commercialize Traficet-EN, is currently evaluating its option to CCX354, and will have similar option rights to CCX168 and CCX832 if the company establishs clinical proof-of-concept. All of its drug candidates have been internally discovered and include: Traficet-EN (CCX282 or GSK'786) — Its advanced drug candidate, currently in three pivotal Phase III clinical trials being conducted by its partner GSK for the treatment of patients with moderate-to-severe Crohn's disease; CCX140 —an independent drug candidate successfully completed a Phase II clinical trial in type 2 diabetics and is currently in two Phase II clinical trials in patients with diabetic nephropathy, a form of kidney disease; CCX354 — Successfully completed a Phase II proof-of-concept clinical trial for the treatment of rheumatoid arthritis, or RA, and the company expects GSK's option decision by the end of 2011; CCX168 — Currently in a Phase II proof-of-concept clinical trial for the treatment of anti-neutrophil cytoplasmic antibody, or ANCA-associated vasculitis, or AAV, and is subject to GSK's option; CCX832 — Recently completed a Phase I clinical trial. Subject to further discussion with GSK, expected to enter a Phase II proof-of-concept clinical trial for the treatment of skin inflammation, and is subject to GSK's option; and CCX662 — its independent drug candidate for the treatment of glioblastoma multiforme, or GBM, is expected to enter a Phase I clinical trial in the second half of 2012. The company's strategies includes the following: collaborate with its partner GSK in the Phase III clinical development and commercialization of Traficet-EN; Forward integrate into a commercial biopharmaceutical company by driving the development and commercialization of it independent drug candidate, CCX140; Expanding its clinical stage portfolio of internally discovered, independent drug candidates; Commercializing drug candidates in specialty markets in North America and par
Company Website
SEC Reports
Industry: Biotechnology
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Traded in other countries:2CX.Germany
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