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Also traded in: Germany

GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength : 4/10

vs
industry
vs
history
Cash to Debt No Debt
SYN's Cash to Debt is ranked higher than
94% of the 930 Companies
in the Global Biotechnology industry.

( Industry Median: 56.38 vs. SYN: No Debt )
Ranked among companies with meaningful Cash to Debt only.
SYN' s Cash to Debt Range Over the Past 10 Years
Min: 0.02  Med: 10000.00 Max: No Debt
Current: No Debt
Interest Coverage No Debt
SYN's Interest Coverage is ranked higher than
92% of the 364 Companies
in the Global Biotechnology industry.

( Industry Median: 9999.00 vs. SYN: No Debt )
Ranked among companies with meaningful Interest Coverage only.
SYN' s Interest Coverage Range Over the Past 10 Years
Min: 9999.99  Med: 10000.00 Max: 9999.99
Current: No Debt
F-Score: 3
Z-Score: -10.02
M-Score: -13.25
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth : 3/10

vs
industry
vs
history
ROE (%) -641.88
SYN's ROE (%) is ranked lower than
98% of the 851 Companies
in the Global Biotechnology industry.

( Industry Median: -32.29 vs. SYN: -641.88 )
Ranked among companies with meaningful ROE (%) only.
SYN' s ROE (%) Range Over the Past 10 Years
Min: -341.6  Med: -120.20 Max: -48.04
Current: -641.88
-341.6
-48.04
ROA (%) -173.37
SYN's ROA (%) is ranked lower than
93% of the 934 Companies
in the Global Biotechnology industry.

( Industry Median: -27.73 vs. SYN: -173.37 )
Ranked among companies with meaningful ROA (%) only.
SYN' s ROA (%) Range Over the Past 10 Years
Min: -174.99  Med: -79.33 Max: -41.8
Current: -173.37
-174.99
-41.8
ROC (Joel Greenblatt) (%) -13058.43
SYN's ROC (Joel Greenblatt) (%) is ranked lower than
90% of the 897 Companies
in the Global Biotechnology industry.

( Industry Median: -356.62 vs. SYN: -13058.43 )
Ranked among companies with meaningful ROC (Joel Greenblatt) (%) only.
SYN' s ROC (Joel Greenblatt) (%) Range Over the Past 10 Years
Min: -14661.9  Med: -915.08 Max: -176.91
Current: -13058.43
-14661.9
-176.91
EBITDA Growth (3Y)(%) 0.90
SYN's EBITDA Growth (3Y)(%) is ranked higher than
53% of the 498 Companies
in the Global Biotechnology industry.

( Industry Median: -2.10 vs. SYN: 0.90 )
Ranked among companies with meaningful EBITDA Growth (3Y)(%) only.
SYN' s EBITDA Growth (3Y)(%) Range Over the Past 10 Years
Min: 0  Med: 0.00 Max: 64.9
Current: 0.9
0
64.9
EPS Growth (3Y)(%) 2.90
SYN's EPS Growth (3Y)(%) is ranked higher than
59% of the 492 Companies
in the Global Biotechnology industry.

( Industry Median: -4.90 vs. SYN: 2.90 )
Ranked among companies with meaningful EPS Growth (3Y)(%) only.
SYN' s EPS Growth (3Y)(%) Range Over the Past 10 Years
Min: 0  Med: 0.00 Max: 52.6
Current: 2.9
0
52.6
» SYN's 10-Y Financials

Financials (Next Earnings Date: Est. 2016-08-10)


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow
Oprt. Cash Flow & Net Income

» Details

Guru Trades

Q4 2014

SYN Guru Trades in Q4 2014

Chuck Royce Sold Out
» More
Q3 2015

SYN Guru Trades in Q3 2015

Ken Fisher 10,500 sh (New)
» More
Q4 2015

SYN Guru Trades in Q4 2015

Ken Fisher 10,500 sh (unchged)
» More
Q1 2016

SYN Guru Trades in Q1 2016

Ken Fisher 10,500 sh (unchged)
» More
» Details

Insider Trades

Latest Guru Trades with SYN

(List those with share number changes of more than 20%, or impact to portfolio more than 0.1%)

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Business Description

Industry: Biotechnology » Biotechnology
Compare:NAS:RDHL, OTCPK:MDGEF, NAS:GLYC, OTCPK:RNUGF, NYSE:EVGN, NAS:AXSM, OTCPK:CTIX, NAS:CDXC, NAS:FBIO, OTCPK:RCAR, NAS:CDTX, NAS:IMDZ, AMEX:PIP, NAS:CARA, NAS:CDXS, NAS:KMDA, NAS:OVAS, NAS:EGLT, NAS:VCYT, NAS:MDWD » details
Traded in other countries:SFYB.Germany,
Synthetic Biologics Inc is a biotechnology company focused on the development of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and other diseases.

Synthetic Biologics Inc was incorporated in 1986 as Sheffield Pharmaceuticals, Inc. The Company is a biotechnology company focused on the development of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and other diseases. Its developing an oral treatment to reduce the impact of methane producing organisms on constipation-predominant irritable bowel syndrome or C-IBS, an oral biologic to protect the gastrointestinal or GI microflora from the effects of intravenous or IV antibiotics for the prevention of Clostridium difficile or C. diff infection, a series of monoclonal antibodies or mAbs for the treatment of Pertussis and Acinetobacter infections, and a biologic targeted at the prevention and treatment of a root cause of a subset of IBS. In addition, it has two legacy programs. Its developing an oral estriol drug for the treatment of relapsing-remitting multiple sclerosis or MS and cognitive dysfunction in MS. It also partnered the development of a treatment for fibromyalgia. Trimesta or oral estriol is being developed as an oral once-daily treatment for relapsing-remitting MS in women. Trimesta is also being developed for the treatment of cognitive dysfunction in female MS patients. This 12-month randomized, double-blind, placebo-controlled Phase II clinical trial is being conducted at UCLA. There are nine FDA-approved therapies for the treatment of relapsing-remitting MS: Betaseron, Rebif, Avonex, Copaxone, Tysabri, Gilenya, Extavia, Aubagio and Tecfidera. Effirma or flupirtine is being developed for the treatment of fibromyalgia by Meda AB. Current FDA-approved therapies for the treatment of C-IBS include AMITIZA or lubiprostone and LINZESS or linaclotide. The Company utilizes contract manufacturing firms to produce its investigational products Trimesta and SYN-004 in accordance with current good manufacturing processes or cGMP guidelines outlined by the FDA. It competes with Actelion Pharmaceuticals, Bayer Health Care, Biogen Idec, Eli Lilly & Co., Genzyme, GlaxoSmithKline Pharmaceuticals, Merck & Co., Pfizer, Novartis, Teva Pharmaceuticals and United Therapeutics, among others. The Company is subject to various government FDA, FTC, CPSC and USDA regulations.

Ratios

vs
industry
vs
history
P/B 24.67
SYN's P/B is ranked lower than
95% of the 1024 Companies
in the Global Biotechnology industry.

( Industry Median: 3.30 vs. SYN: 24.67 )
Ranked among companies with meaningful P/B only.
SYN' s P/B Range Over the Past 10 Years
Min: 1.67  Med: 5.92 Max: 25.81
Current: 24.67
1.67
25.81
Current Ratio 1.27
SYN's Current Ratio is ranked lower than
86% of the 903 Companies
in the Global Biotechnology industry.

( Industry Median: 4.55 vs. SYN: 1.27 )
Ranked among companies with meaningful Current Ratio only.
SYN' s Current Ratio Range Over the Past 10 Years
Min: 0.03  Med: 5.67 Max: 58.44
Current: 1.27
0.03
58.44
Quick Ratio 1.27
SYN's Quick Ratio is ranked lower than
82% of the 903 Companies
in the Global Biotechnology industry.

( Industry Median: 4.25 vs. SYN: 1.27 )
Ranked among companies with meaningful Quick Ratio only.
SYN' s Quick Ratio Range Over the Past 10 Years
Min: 0.03  Med: 5.76 Max: 58.44
Current: 1.27
0.03
58.44

Valuation & Return

vs
industry
vs
history
Price/Net Current Asset Value 28.33
SYN's Price/Net Current Asset Value is ranked lower than
89% of the 829 Companies
in the Global Biotechnology industry.

( Industry Median: 4.80 vs. SYN: 28.33 )
Ranked among companies with meaningful Price/Net Current Asset Value only.
SYN' s Price/Net Current Asset Value Range Over the Past 10 Years
Min: 0.72  Med: 8.33 Max: 39.33
Current: 28.33
0.72
39.33
Price/Tangible Book 24.29
SYN's Price/Tangible Book is ranked lower than
92% of the 957 Companies
in the Global Biotechnology industry.

( Industry Median: 4.02 vs. SYN: 24.29 )
Ranked among companies with meaningful Price/Tangible Book only.
SYN' s Price/Tangible Book Range Over the Past 10 Years
Min: 0.55  Med: 7.90 Max: 34.2
Current: 24.29
0.55
34.2
Earnings Yield (Greenblatt) (%) -31.38
SYN's Earnings Yield (Greenblatt) (%) is ranked lower than
77% of the 1104 Companies
in the Global Biotechnology industry.

( Industry Median: -9.68 vs. SYN: -31.38 )
Ranked among companies with meaningful Earnings Yield (Greenblatt) (%) only.
SYN' s Earnings Yield (Greenblatt) (%) Range Over the Past 10 Years
Min: -59  Med: 0.00 Max: 0
Current: -31.38
-59
0

More Statistics

EPS (TTM) $ -0.55
Beta1.91
Short Percentage of Float15.01%
52-Week Range $0.93 - 3.55
Shares Outstanding (Mil)90.83

Analyst Estimate


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Dec16 Dec17 Dec18
Revenue (Mil $)
EPS ($) -0.58 -0.70 -0.88
EPS w/o NRI ($) -0.58 -0.70 -0.88
EPS Growth Rate
(3Y to 5Y Estimate)
N/A
Dividends Per Share ($)
» More Articles for SYN

Headlines

Articles On GuruFocus.com
Synodon Inc. – A Breakthrough Technology For Pipeline Safety Jan 28 2013 

More From Other Websites
Synthetic Biologics Announces Granting of European and U.S. Composition of Matter Patents for... Jul 12 2016
Synthetic Biologics Announces Granting of European and U.S. Composition of Matter Patents for... Jul 12 2016
Synthetic Biologics Receives USAN Approval for Generic Name Ribaxamase for Phase 2 Drug Candidate... Jul 07 2016
Synthetic Biologics Receives USAN Approval for Generic Name Ribaxamase for Phase 2 Drug Candidate... Jul 07 2016
Synthetic Biologics to Present at the 2nd Annual Cantor Fitzgerald Healthcare Conference Jul 06 2016
Synthetic Biologics to Present at the 2nd Annual Cantor Fitzgerald Healthcare Conference Jul 06 2016
Basic Materials: Recent Commodity Rallies Leave Few Opportunities Jun 30 2016
SYNTHETIC BIOLOGICS, INC. Files SEC form 8-K, Regulation FD Disclosure, Financial Statements and... Jun 27 2016
Synthetic Biologics, Inc. :SYN-US: Earnings Analysis: Q1, 2016 By the Numbers : June 6, 2016 Jun 06 2016
Premarket Research Report Covering the Biotech Industry Jun 06 2016
Synthetic Biologics Announces Detailed Data from Two SYN-010 Phase 2 Clinical Trials for the... May 23 2016
Synthetic Biologics Announces Detailed Data from Two SYN-010 Phase 2 Clinical Trials for the... May 23 2016
SYNTHETIC BIOLOGICS, INC. Files SEC form 8-K, Regulation FD Disclosure, Financial Statements and... May 23 2016
Synthetic Biologics to Host Post-DDW 2016® Conference Call to Recap SYN-010 Phase 2 Clinical Trial... May 17 2016
Synthetic Biologics to Host Post-DDW 2016® Conference Call to Recap SYN-010 Phase 2 Clinical Trial... May 17 2016
Synthetic Biologics Announces Positive Topline Results from Second Phase 2a Clinical Trial of... May 16 2016
Synthetic Biologics Announces Positive Topline Results from Second Phase 2a Clinical Trial of... May 16 2016
SYNTHETIC BIOLOGICS, INC. Financials May 13 2016
Isaac J. Bright, MD, Joins Synthetic Biologics as Vice President, Corporate Development May 11 2016
Isaac J. Bright, MD, Joins Synthetic Biologics as Vice President, Corporate Development May 11 2016

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