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GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength : 5/10

vs
industry
vs
history
Cash to Debt No Debt
THLD's Cash to Debt is ranked higher than
94% of the 860 Companies
in the Global Biotechnology industry.

( Industry Median: 61.94 vs. THLD: No Debt )
Ranked among companies with meaningful Cash to Debt only.
THLD' s 10-Year Cash to Debt Range
Min: 17.14  Med: 10000.00 Max: No Debt
Current: No Debt
Equity to Asset -0.36
THLD's Equity to Asset is ranked lower than
95% of the 617 Companies
in the Global Biotechnology industry.

( Industry Median: 0.68 vs. THLD: -0.36 )
Ranked among companies with meaningful Equity to Asset only.
THLD' s 10-Year Equity to Asset Range
Min: -0.86  Med: 0.20 Max: 0.88
Current: -0.36
-0.86
0.88
Interest Coverage No Debt
THLD's Interest Coverage is ranked higher than
88% of the 381 Companies
in the Global Biotechnology industry.

( Industry Median: 10000.00 vs. THLD: No Debt )
Ranked among companies with meaningful Interest Coverage only.
THLD' s 10-Year Interest Coverage Range
Min: 725.64  Med: 10000.00 Max: 9999.99
Current: No Debt
725.64
9999.99
F-Score: 3
Z-Score: -6.12
M-Score: -2.51
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth : 3/10

vs
industry
vs
history
Operating margin (%) -229.18
THLD's Operating margin (%) is ranked lower than
62% of the 677 Companies
in the Global Biotechnology industry.

( Industry Median: -71.14 vs. THLD: -229.18 )
Ranked among companies with meaningful Operating margin (%) only.
THLD' s 10-Year Operating margin (%) Range
Min: -48445.16  Med: -1776.88 Max: -208.28
Current: -229.18
-48445.16
-208.28
Net-margin (%) -225.30
THLD's Net-margin (%) is ranked lower than
64% of the 677 Companies
in the Global Biotechnology industry.

( Industry Median: -67.10 vs. THLD: -225.30 )
Ranked among companies with meaningful Net-margin (%) only.
THLD' s 10-Year Net-margin (%) Range
Min: -41375.81  Med: -1702.83 Max: -146.61
Current: -225.3
-41375.81
-146.61
ROA (%) -42.40
THLD's ROA (%) is ranked lower than
64% of the 866 Companies
in the Global Biotechnology industry.

( Industry Median: -27.09 vs. THLD: -42.40 )
Ranked among companies with meaningful ROA (%) only.
THLD' s 10-Year ROA (%) Range
Min: -132.78  Med: -65.37 Max: -25.02
Current: -42.4
-132.78
-25.02
ROC (Joel Greenblatt) (%) -6001.42
THLD's ROC (Joel Greenblatt) (%) is ranked lower than
81% of the 838 Companies
in the Global Biotechnology industry.

( Industry Median: -390.34 vs. THLD: -6001.42 )
Ranked among companies with meaningful ROC (Joel Greenblatt) (%) only.
THLD' s 10-Year ROC (Joel Greenblatt) (%) Range
Min: -8350.75  Med: -2871.74 Max: 2566.56
Current: -6001.42
-8350.75
2566.56
EBITDA Growth (3Y)(%) -9.80
THLD's EBITDA Growth (3Y)(%) is ranked lower than
57% of the 429 Companies
in the Global Biotechnology industry.

( Industry Median: -4.70 vs. THLD: -9.80 )
Ranked among companies with meaningful EBITDA Growth (3Y)(%) only.
THLD' s 10-Year EBITDA Growth (3Y)(%) Range
Min: -73.4  Med: -42.60 Max: -9.8
Current: -9.8
-73.4
-9.8
EPS Growth (3Y)(%) -13.70
THLD's EPS Growth (3Y)(%) is ranked lower than
59% of the 418 Companies
in the Global Biotechnology industry.

( Industry Median: -6.80 vs. THLD: -13.70 )
Ranked among companies with meaningful EPS Growth (3Y)(%) only.
THLD' s 10-Year EPS Growth (3Y)(%) Range
Min: -85.5  Med: -45.25 Max: 2.7
Current: -13.7
-85.5
2.7
» THLD's 10-Y Financials

Financials


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow

» Details

Guru Trades

Q3 2014

THLD Guru Trades in Q3 2014

First Eagle Investment 1,091,700 sh (+36.46%)
Jim Simons 40,700 sh (-89.90%)
» More
Q4 2014

THLD Guru Trades in Q4 2014

Jim Simons 177,615 sh (+336.40%)
First Eagle Investment 1,377,448 sh (+26.17%)
» More
Q1 2015

THLD Guru Trades in Q1 2015

Jim Simons 346,308 sh (+94.98%)
First Eagle Investment 1,405,768 sh (+2.06%)
» More
Q2 2015

THLD Guru Trades in Q2 2015

Jim Simons 422,103 sh (+21.89%)
First Eagle Investment 1,270,768 sh (-9.60%)
» More
» Details

Insider Trades

Latest Guru Trades with THLD

(List those with share number changes of more than 20%, or impact to portfolio more than 0.1%)

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Ratios

vs
industry
vs
history
P/S 18.49
THLD's P/S is ranked lower than
64% of the 604 Companies
in the Global Biotechnology industry.

( Industry Median: 10.47 vs. THLD: 18.49 )
Ranked among companies with meaningful P/S only.
THLD' s 10-Year P/S Range
Min: 1.77  Med: 38.82 Max: 1242
Current: 18.49
1.77
1242
Current Ratio 2.83
THLD's Current Ratio is ranked lower than
63% of the 837 Companies
in the Global Biotechnology industry.

( Industry Median: 4.14 vs. THLD: 2.83 )
Ranked among companies with meaningful Current Ratio only.
THLD' s 10-Year Current Ratio Range
Min: 1.48  Med: 5.10 Max: 13.48
Current: 2.83
1.48
13.48
Quick Ratio 2.83
THLD's Quick Ratio is ranked lower than
60% of the 837 Companies
in the Global Biotechnology industry.

( Industry Median: 4.00 vs. THLD: 2.83 )
Ranked among companies with meaningful Quick Ratio only.
THLD' s 10-Year Quick Ratio Range
Min: 1.48  Med: 5.10 Max: 13.48
Current: 2.83
1.48
13.48
Days Sales Outstanding 90.42
THLD's Days Sales Outstanding is ranked lower than
67% of the 570 Companies
in the Global Biotechnology industry.

( Industry Median: 62.77 vs. THLD: 90.42 )
Ranked among companies with meaningful Days Sales Outstanding only.
THLD' s 10-Year Days Sales Outstanding Range
Min: 179.7  Med: 528.56 Max: 972.69
Current: 90.42
179.7
972.69

Valuation & Return

vs
industry
vs
history
Price/Median PS Value 0.46
THLD's Price/Median PS Value is ranked higher than
84% of the 542 Companies
in the Global Biotechnology industry.

( Industry Median: 1.07 vs. THLD: 0.46 )
Ranked among companies with meaningful Price/Median PS Value only.
THLD' s 10-Year Price/Median PS Value Range
Min: 0.08  Med: 0.64 Max: 30.11
Current: 0.46
0.08
30.11
Earnings Yield (Greenblatt) (%) -14.92
THLD's Earnings Yield (Greenblatt) (%) is ranked lower than
68% of the 823 Companies
in the Global Biotechnology industry.

( Industry Median: -6.10 vs. THLD: -14.92 )
Ranked among companies with meaningful Earnings Yield (Greenblatt) (%) only.
THLD' s 10-Year Earnings Yield (Greenblatt) (%) Range
Min: -14.92  Med: 297.90 Max: 14657.5
Current: -14.92
-14.92
14657.5

Analyst Estimate

Dec15 Dec16 Dec17
Revenue(Mil) 15 20 41
EPS($) -0.53 -0.51 -0.08
EPS without NRI($) -0.53 -0.51 -0.08

Business Description

Industry: Biotechnology » Biotechnology
Compare:NVO, AMGN, GILD, BIIB, CELG » details
Traded in other countries:NZW1.Germany,
Threshold Pharmaceuticals Inc is a Delaware corporation incorporated on October 17, 2001. It's a biotechnology company focused on the discovery and development of drugs targeting the microenvironment of solid tumors as novel treatments for patients living with cancer. The microenvironment of these tissues is characterized by hypoxia or lack of oxygen. Its hypoxia activated prodrug ("HAP") product candidates, including TH-302, are designed to specifically target the hypoxic microenvironment of tumors by selective activation of the prodrug to release a potent cytotoxin. Its focus is on product candidates for the treatment of patients with cancer. Its clinical development efforts are currently engaged in TH-302, for which it entered a license and co-development agreement with Merck KGaA for development and commercialization. TH-302 is a novel drug candidate that is activated under severe hypoxic conditions and was designed to specifically target the severe hypoxic regions that are believed to be present in all solid tumors and hematologic malignancies. The production of TH-302 employs small molecule organic chemistry procedures that are standard for the pharmaceutical industry. It currently relies on contract manufacturers for the manufacture of active pharmaceutical ingredient ("API"), and final drug product of TH-302. Under its license and co-development agreement with Merck KGaA, the Company is dependent on Merck for clinical and commercial supply of TH-302, except for clinical trials for United States approval of TH-302 for soft tissue sarcoma and for any other clinical trials for which it is responsible. For these latter cases, it can obtain clinical supply directly from existing or new suppliers. It currently uses contract manufacturers to manufacture TH-302 API and TH-302 drug product. The commercial sale for pancreatic cancer, TH-302 would compete with Gemzar, marketed by Eli Lilly and Company; Tarceva, marketed by Genentech and Astellas Oncology; Abraxane marketed by Celgene; and FOLFIRINOX. The manufacturing and marketing of its potential products and its ongoing research and development activities are subject to extensive regulation by the FDA and comparable regulatory agencies in state and local jurisdictions and in foreign countries.
» More Articles for THLD

Headlines

Articles On GuruFocus.com
Threshold Pharmaceuticals Initiates Phase 2 Clinical Trial of Tarloxotinib Bromide* (TH-4000) in Pat Aug 27 2015 
Threshold Pharmaceuticals and ATOMIC Initiate First Phase 2 Clinical Trial of Tarloxotinib Bromide* Aug 11 2015 
Threshold Pharmaceuticals Announces Presentation and Webcast at the Cantor Fitzgerald Healthcare Con Jul 01 2015 
Tuesday Pre-Market Insights: THLD, PLL, AOL, CALL May 12 2015 
Encouraging Initial Data From Ongoing Phase 1/2 Trial of TH-302 Plus Bortezomib (Velcade(R)) Plus De Dec 06 2014 
Threshold Pharmaceuticals Announces Presentations and Webcasts at Upcoming Investor Meetings in Dece Nov 25 2014 
Threshold Pharmaceuticals Announces Phase 1/2 Interim Data Signaling Activity of TH-302 Plus Bevaciz Nov 17 2014 
Threshold Pharmaceuticals Receives FDA Fast Track Designation for TH-302 for the Treatment of Previo Nov 11 2014 
Threshold Pharmaceuticals Announces Presentation and Webcast at the Stifel 2014 Healthcare Conferenc Nov 10 2014 
Threshold Pharmaceuticals Announces New Phase 1/2 Data on TH-302 in Multiple Myeloma to Be Presented Nov 06 2014 

More From Other Websites
Threshold Pharmaceuticals Initiates Phase 2 Clinical Trial of Tarloxotinib Bromide* (TH-4000) in... Aug 27 2015
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Threshold Pharmaceuticals, Inc. Earnings Q2, 2015 Aug 26 2015
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10-Q for Threshold Pharmaceuticals, Inc. Aug 01 2015
THLD: Update on 2Q15 Financials Jul 31 2015
Threshold Pharmaceuticals posts 2Q loss Jul 30 2015
Threshold Pharmaceuticals posts 2Q loss Jul 30 2015
Threshold Pharmaceuticals Reports Second Quarter 2015 Financial and Operational Results Jul 30 2015
THRESHOLD PHARMACEUTICALS INC Files SEC form 8-K, Results of Operations and Financial Condition,... Jul 30 2015
Threshold Pharmaceuticals Reports Second Quarter 2015 Financial and Operational Results Jul 30 2015
Cantor Still Expects Threshold Pharma To More Than Triple, Says 2016 Will Be 'Data Rich' Year Jul 02 2015
Threshold Pharmaceuticals Announces Presentation and Webcast at the Cantor Fitzgerald Healthcare... Jul 01 2015
THRESHOLD PHARMACEUTICALS INC Files SEC form 8-K, Change in Directors or Principal Officers Jun 10 2015
THRESHOLD PHARMACEUTICALS INC Files SEC form 8-K, Submission of Matters to a Vote of Security... Jun 01 2015

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