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Also traded in: Germany, Mexico, Switzerland, UK

GuruFocus Financial Strength Rank measures how strong a company’s financial situation is. It is based on these factors

1. The debt burden that the company has as measured by its Interest coverage (current year).
2. Debt to revenue ratio. The lower, the better
3. Altman Z-score.

A company ranks high with financial strength is likely to withstand any business slowdowns and recessions.

Financial Strength : 6/10

vs
industry
vs
history
Cash to Debt 1.38
VRTX's Cash to Debt is ranked lower than
77% of the 963 Companies
in the Global Biotechnology industry.

( Industry Median: 83.29 vs. VRTX: 1.38 )
Ranked among companies with meaningful Cash to Debt only.
VRTX' s Cash to Debt Range Over the Past 10 Years
Min: 0.92  Med: 2.11 Max: 26.61
Current: 1.38
0.92
26.61
Equity to Asset 0.39
VRTX's Equity to Asset is ranked lower than
77% of the 711 Companies
in the Global Biotechnology industry.

( Industry Median: 0.67 vs. VRTX: 0.39 )
Ranked among companies with meaningful Equity to Asset only.
VRTX' s Equity to Asset Range Over the Past 10 Years
Min: -0.02  Med: 0.46 Max: 0.95
Current: 0.39
-0.02
0.95
F-Score: 5
Z-Score: 6.11
M-Score: -2.35
WACC vs ROIC
15.28%
-9.09%
WACC
ROIC
GuruFocus Profitability Rank ranks how profitable a company is and how likely the company’s business will stay that way. It is based on these factors:

1. Operating Margin
2. Trend of the Operating Margin (5-year average). The company with an uptrend profit margin has a higher rank.
••3. Consistency of the profitability
4. Piotroski F-Score
5. Predictability Rank•

The maximum rank is 10. A rank of 7 or higher means a higher profitability and may stay that way. A rank of 3 or lower indicates that the company has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength Rank. But if a company is consistently profitable, its financial strength will be stronger.

Profitability & Growth : 5/10

vs
industry
vs
history
Operating margin (%) -5.02
VRTX's Operating margin (%) is ranked higher than
69% of the 745 Companies
in the Global Biotechnology industry.

( Industry Median: -81.51 vs. VRTX: -5.02 )
Ranked among companies with meaningful Operating margin (%) only.
VRTX' s Operating margin (%) Range Over the Past 10 Years
Min: -602.63  Med: -112.58 Max: 8.07
Current: -5.02
-602.63
8.07
Net-margin (%) -13.17
VRTX's Net-margin (%) is ranked higher than
66% of the 745 Companies
in the Global Biotechnology industry.

( Industry Median: -76.71 vs. VRTX: -13.17 )
Ranked among companies with meaningful Net-margin (%) only.
VRTX' s Net-margin (%) Range Over the Past 10 Years
Min: -630.27  Med: -111.44 Max: 2.1
Current: -13.17
-630.27
2.1
ROE (%) -22.68
VRTX's ROE (%) is ranked higher than
59% of the 875 Companies
in the Global Biotechnology industry.

( Industry Median: -32.93 vs. VRTX: -22.68 )
Ranked among companies with meaningful ROE (%) only.
VRTX' s ROE (%) Range Over the Past 10 Years
Min: -180.27  Med: -58.14 Max: 4.58
Current: -22.68
-180.27
4.58
ROA (%) -8.69
VRTX's ROA (%) is ranked higher than
69% of the 967 Companies
in the Global Biotechnology industry.

( Industry Median: -29.03 vs. VRTX: -8.69 )
Ranked among companies with meaningful ROA (%) only.
VRTX' s ROA (%) Range Over the Past 10 Years
Min: -58.14  Med: -29.94 Max: 1.51
Current: -8.69
-58.14
1.51
ROC (Joel Greenblatt) (%) -12.01
VRTX's ROC (Joel Greenblatt) (%) is ranked higher than
74% of the 927 Companies
in the Global Biotechnology industry.

( Industry Median: -368.19 vs. VRTX: -12.01 )
Ranked among companies with meaningful ROC (Joel Greenblatt) (%) only.
VRTX' s ROC (Joel Greenblatt) (%) Range Over the Past 10 Years
Min: -1092.55  Med: -251.29 Max: 110.77
Current: -12.01
-1092.55
110.77
Revenue Growth (3Y)(%) -15.50
VRTX's Revenue Growth (3Y)(%) is ranked lower than
70% of the 484 Companies
in the Global Biotechnology industry.

( Industry Median: 4.50 vs. VRTX: -15.50 )
Ranked among companies with meaningful Revenue Growth (3Y)(%) only.
VRTX' s Revenue Growth (3Y)(%) Range Over the Past 10 Years
Min: -32.5  Med: 8.1 Max: 129.4
Current: -15.5
-32.5
129.4
» VRTX's 10-Y Financials

Financials


Revenue & Net Income
Cash & Debt
Oprt. Cash Flow & Free Cash Flow
Oprt. Cash Flow & Net Income

» Details

Guru Trades

Q4 2015

VRTX Guru Trades in Q4 2015

Jim Simons 61,317 sh (New)
Paul Tudor Jones 6,286 sh (New)
Joel Greenblatt 11,793 sh (New)
John Paulson 46,400 sh (New)
Pioneer Investments 767,325 sh (+14.39%)
Ken Fisher 5,543 sh (+12.48%)
Andreas Halvorsen 1,421,673 sh (+5.74%)
Vanguard Health Care Fund 9,827,411 sh (+4.34%)
Louis Moore Bacon 50,000 sh (unchged)
Spiros Segalas 657,494 sh (unchged)
Steven Cohen Sold Out
Kyle Bass Sold Out
» More
Q1 2016

VRTX Guru Trades in Q1 2016

David Carlson 230,000 sh (New)
Steven Cohen 838,700 sh (New)
Leucadia National 3,300 sh (New)
Samuel Isaly 162,000 sh (New)
Jim Simons 112,617 sh (+83.66%)
John Paulson 61,500 sh (+32.54%)
Vanguard Health Care Fund 12,668,241 sh (+28.91%)
Pioneer Investments 876,770 sh (+14.26%)
Andreas Halvorsen Sold Out
Paul Tudor Jones Sold Out
Ken Fisher 5,155 sh (-7.00%)
Joel Greenblatt 5,046 sh (-57.21%)
» More
Q2 2016

VRTX Guru Trades in Q2 2016

Manning & Napier Advisors, Inc 126,990 sh (New)
George Soros 6,300 sh (New)
Joel Greenblatt 108,656 sh (+2053.31%)
Pioneer Investments 1,111,794 sh (+26.81%)
David Carlson 270,000 sh (+17.39%)
Vanguard Health Care Fund 12,914,741 sh (+1.95%)
Samuel Isaly 528,100 sh (+225.99%)
John Paulson Sold Out
Steven Cohen Sold Out
Leucadia National Sold Out
Ken Fisher 5,112 sh (-0.83%)
Jim Simons 60,517 sh (-46.26%)
» More
Q3 2016

VRTX Guru Trades in Q3 2016

John Burbank 2,830 sh (New)
Jeremy Grantham 50,300 sh (New)
Manning & Napier Advisors, Inc 142,540 sh (+12.25%)
Pioneer Investments 1,231,092 sh (+10.73%)
Ken Fisher 5,168 sh (+1.10%)
Vanguard Health Care Fund 12,914,741 sh (unchged)
David Carlson 270,000 sh (unchged)
Jeremy Grantham 100,000 sh (unchged)
Jim Simons Sold Out
George Soros Sold Out
Joel Greenblatt 66,716 sh (-38.60%)
Samuel Isaly 269,807 sh (-48.91%)
» More
» Details

Insider Trades

Latest Guru Trades with VRTX

(List those with share number changes of more than 20%, or impact to portfolio more than 0.1%)

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Business Description

Industry: Biotechnology » Biotechnology
Compare:NAS:INCY, OTCPK:ALIOY, NAS:ALXN, NAS:BMRN, OTCPK:GIKLY, NAS:MDVN, OTCPK:UCBJY, OTCPK:GMXAY, OTCPK:NVZMF, NAS:SGEN, OTCPK:CSLLY, NAS:ALKS, NAS:TSRO, NAS:JAZZ, NAS:UTHR, NAS:IONS, NAS:EXEL, NAS:ALNY, NAS:TECH, NYSE:XON » details
Traded in other countries:VX1.Germany, VRTX.Mexico, VRTX.Switzerland, 0QZU.UK,
Vertex Pharmaceuticals Inc is engaged in the business of discovering, developing, manufacturing and commercializing small molecule drugs for patients with serious diseases in specialty markets.

Vertex Pharmaceuticals Inc was incorporated in 1989. The Company is engaged in the business of discovering, developing, manufacturing and commercializing small molecule drugs for patients with serious diseases in specialty markets. It is focused on developing and commercializing therapies for the treatment of cystic fibrosis and advancing its research and early-stage development programs. The Company has marketed KALYDECO (ivacaftor) since it was approved in 2012 for the treatment of certain patients with CF and is seeking approval to market lumacaftor in combination with ivacaftor in order to increase the number of patients with CF who would be eligible for treatment with the Company's drugs. It is engaged in a number of other research and early-stage development programs, including programs in the areas of oncology and neurology. The Company's three products are INCIVE (telaprevir), which is approved for the treatment of patients with genotype 1 hepatitis C virus, or HCV, infection; and KALYDECO (ivacaftor), which is approved in the United States for the treatment of patients six years of age and older with cystic fibrosis, or CF, who genetic mutation in their cystic fibrosis transmembrane conductance regulator, or CFTR, gene, which is referred to as the G551D mutation. INCIVEK is approved in the United States and Canada for the treatment of adults with genotype 1 hepatitis C virus, or HCV, infection and ORKAMBI. The Company began marketing ORKAMBI (lumacaftor in combination with ivacaftor) in the United States in 2015. In November 2015, the European Commission approved ORKAMBI, and the Company is seeking country-by-country reimbursement for ORKAMBI in Europe. As the Company markets and sells its approved products and advances its drug candidates through clinical development toward commercialization, it continues to build and maintain its supply chain and quality assurance resources. It faces competition based on the safety and efficacy of its products and drug candidates, the timing and scope of regulatory approvals, the availability and cost of supply, marketing and sales capabilities, reimbursement coverage, price, patent protection and other factors. Its registered trademarks include Vertex, KALYDECO and INCIVEK. The research, development, testing, manufacture, quality control, approval, labeling, packaging, storage, safety monitoring, record keeping, promotion, advertising, distribution and marketing of its products and drug candidates are subject to extensive regulation by United States and foreign governmental authorities.

Ratios

vs
industry
vs
history
Forward P/E 29.50
VRTX's Forward P/E is ranked lower than
76% of the 76 Companies
in the Global Biotechnology industry.

( Industry Median: 19.92 vs. VRTX: 29.50 )
Ranked among companies with meaningful Forward P/E only.
N/A
P/B 18.32
VRTX's P/B is ranked lower than
94% of the 1227 Companies
in the Global Biotechnology industry.

( Industry Median: 3.57 vs. VRTX: 18.32 )
Ranked among companies with meaningful P/B only.
VRTX' s P/B Range Over the Past 10 Years
Min: 5.78  Med: 13.58 Max: 37.6
Current: 18.32
5.78
37.6
P/S 11.10
VRTX's P/S is ranked lower than
51% of the 978 Companies
in the Global Biotechnology industry.

( Industry Median: 12.03 vs. VRTX: 11.10 )
Ranked among companies with meaningful P/S only.
VRTX' s P/S Range Over the Past 10 Years
Min: 4.38  Med: 19.39 Max: 77.75
Current: 11.1
4.38
77.75
POCF 152.84
VRTX's POCF is ranked lower than
93% of the 238 Companies
in the Global Biotechnology industry.

( Industry Median: 20.45 vs. VRTX: 152.84 )
Ranked among companies with meaningful POCF only.
VRTX' s POCF Range Over the Past 10 Years
Min: 11.43  Med: 46.58 Max: 236.03
Current: 152.84
11.43
236.03
Current Ratio 2.08
VRTX's Current Ratio is ranked lower than
74% of the 946 Companies
in the Global Biotechnology industry.

( Industry Median: 4.23 vs. VRTX: 2.08 )
Ranked among companies with meaningful Current Ratio only.
VRTX' s Current Ratio Range Over the Past 10 Years
Min: 1.73  Med: 4.27 Max: 30.95
Current: 2.08
1.73
30.95
Quick Ratio 1.98
VRTX's Quick Ratio is ranked lower than
71% of the 946 Companies
in the Global Biotechnology industry.

( Industry Median: 3.98 vs. VRTX: 1.98 )
Ranked among companies with meaningful Quick Ratio only.
VRTX' s Quick Ratio Range Over the Past 10 Years
Min: 1.62  Med: 4.27 Max: 30.95
Current: 1.98
1.62
30.95
Days Inventory 105.38
VRTX's Days Inventory is ranked higher than
59% of the 448 Companies
in the Global Biotechnology industry.

( Industry Median: 129.09 vs. VRTX: 105.38 )
Ranked among companies with meaningful Days Inventory only.
VRTX' s Days Inventory Range Over the Past 10 Years
Min: 62.49  Med: 129.06 Max: 254.87
Current: 105.38
62.49
254.87
Days Sales Outstanding 40.03
VRTX's Days Sales Outstanding is ranked higher than
69% of the 595 Companies
in the Global Biotechnology industry.

( Industry Median: 63.02 vs. VRTX: 40.03 )
Ranked among companies with meaningful Days Sales Outstanding only.
VRTX' s Days Sales Outstanding Range Over the Past 10 Years
Min: 25.75  Med: 47.58 Max: 106.15
Current: 40.03
25.75
106.15
Days Payable 87.10
VRTX's Days Payable is ranked higher than
63% of the 412 Companies
in the Global Biotechnology industry.

( Industry Median: 57.68 vs. VRTX: 87.10 )
Ranked among companies with meaningful Days Payable only.
VRTX' s Days Payable Range Over the Past 10 Years
Min: 87.1  Med: 443.5 Max: 1204.41
Current: 87.1
87.1
1204.41

Buy Back

vs
industry
vs
history
3-Year Average Share Buyback Ratio -4.30
VRTX's 3-Year Average Share Buyback Ratio is ranked higher than
74% of the 554 Companies
in the Global Biotechnology industry.

( Industry Median: -11.20 vs. VRTX: -4.30 )
Ranked among companies with meaningful 3-Year Average Share Buyback Ratio only.
VRTX' s 3-Year Average Share Buyback Ratio Range Over the Past 10 Years
Min: -18.1  Med: -11.6 Max: -2.5
Current: -4.3
-18.1
-2.5

Valuation & Return

vs
industry
vs
history
Price/Tangible Book 27.26
VRTX's Price/Tangible Book is ranked lower than
95% of the 1150 Companies
in the Global Biotechnology industry.

( Industry Median: 4.46 vs. VRTX: 27.26 )
Ranked among companies with meaningful Price/Tangible Book only.
VRTX' s Price/Tangible Book Range Over the Past 10 Years
Min: 2.13  Med: 12.51 Max: 120.7
Current: 27.26
2.13
120.7
Price/Median PS Value 0.57
VRTX's Price/Median PS Value is ranked higher than
74% of the 868 Companies
in the Global Biotechnology industry.

( Industry Median: 0.98 vs. VRTX: 0.57 )
Ranked among companies with meaningful Price/Median PS Value only.
VRTX' s Price/Median PS Value Range Over the Past 10 Years
Min: 0.26  Med: 0.99 Max: 3.77
Current: 0.57
0.26
3.77
Earnings Yield (Greenblatt) (%) -0.42
VRTX's Earnings Yield (Greenblatt) (%) is ranked higher than
74% of the 1242 Companies
in the Global Biotechnology industry.

( Industry Median: -8.00 vs. VRTX: -0.42 )
Ranked among companies with meaningful Earnings Yield (Greenblatt) (%) only.
VRTX' s Earnings Yield (Greenblatt) (%) Range Over the Past 10 Years
Min: -0.42  Med: 2.8 Max: 5.4
Current: -0.42
-0.42
5.4

More Statistics

Revenue (TTM) (Mil) $1,661
EPS (TTM) $ -0.90
Beta1.80
Short Percentage of Float3.23%
52-Week Range $73.31 - 132.81
Shares Outstanding (Mil)248.03

Analyst Estimate

Dec16 Dec17 Dec18 Dec19
Revenue (Mil $) 1,688 2,331 2,843 3,573
EPS ($) 0.70 2.42 4.05 6.21
EPS w/o NRI ($) 0.70 2.42 4.05 6.21
EPS Growth Rate
(3Y to 5Y Estimate)
N/A
Dividends Per Share ($)
» More Articles for VRTX

Headlines

Articles On GuruFocus.com
Testing of Treatment for Cystic Fibrosis Patients Begins Nov 29 2016 
Edward Owens Top 2nd Quarter Investments Aug 03 2016 
Vanguard Health Care Fund Ups Stake in High-Conviction Stocks May 10 2016 
Vanguard Boosts Stake in Incyte in 1st Quarter May 02 2016 
Kyle Bass Sells Stakes in 11 Health Care Companies Mar 01 2016 
Lee Ainslie Adds 90 New Stocks to His Portfolio Within the First Quarter May 20 2015 
Analysts Confident That Vertex Pharmaceuticals' CF Drug Will Receive FDA Approval May 13 2015 
Fate Of Cystic Fibrosis Drug By Vertex Is Now Dependent On FDA Approval May 13 2015 
J.P. Morgan Chimes In With Ratings On BioTech Stocks Jan 06 2015 
William Blair’s Top BioPharmaceutical Stock Picks for Q1 2015 Dec 23 2014 

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