Gritstone bio Inc at Goldman Sachs Catalyst Clinic (Virtual) Transcript
I really appreciate the time. And maybe before we kick off and drill down into the GRANITE platform, which should be the focus of most of the conversation, I'd love for you to give kind of a brief overview of the overall business and pipeline that you have over at Gritstone.
Great. Well, first of all, thanks for inviting us to join you today, Corinne. We appreciate it. So Gritstone is now at a very interesting stage in its evolution. We're about eight years old, and we have the GRANITE program, which is personalized cancer vaccine in metastatic colorectal cancer, which is a potentially game-changing opportunity because we've seen immunotherapy, of course, be wildly effective in a variety of solid tumors, but really mostly limited to the so-called hot or inflamed tumor types, PD-L1, high melanoma, MSI tumors, subsets of lung cancer, gastroesophageal, and so on.
What we haven't seen yet is success penetrating into the colder tumor
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